{"title":"The Correlation Of Residual Subjective Cognitive And Depressive Symptoms with Social Functioning in Remitted Major Depressive Disorder Patients","authors":"Ender Kaya, Fatma Barlas","doi":"10.25000/acem.938137","DOIUrl":"https://doi.org/10.25000/acem.938137","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78717677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ö. Karaaslan, Murat Oğuz Özilhan, C. Çöteli, O. Maden
Aim: Prediabetes is known to be associated with increased cardiovascular diseases (CVD) risk and mortality. It has been reported that more than 70% of pre-diabetic patients develop Diabetes Mellitus (DM). In patients with acute myocardial infarction (AMI), diabetes increases a 2 to 4 fold risk of adverse cardiovascular events compared to non-diabetic patients. This morbidity-mortality relationship begins in the progression phase from normal glucose tolerance to diabetes. We evaluated the relationship between the presence of pre-diabetes by using hemoglobin A1c (HbA1c) values and CVD risk in patients presenting with newly diagnosed AMI. Methods: This study was a retrospective, single-centre and we examined consecutive patients who underwent coronary angiography with a diagnosis of AMI at our hospital between March 2019 and September 2020. A total of 332 patients with AMI were enrolled; patients were divided into two groups according to their HbA1c levels: non-diabetic group (HbA1c <5.7%) and pre-diabetic group (5.7% ≤HbA1c <6.05%). The primary composite endpoints were cardiovascular death, myocardial infarction or stroke. Results: Of the 332 patients, 204 (61%) patients had non-diabetic groups, and 128 (39%) patients were between the pre-diabetic groups. During the follow-up period, the primary composite endpoints amounted to 7.4% and 15.6% in the non-diabetes and prediabetes group (p=0.026). The incidences of cardiovascular death and myocardial infarction were significantly higher in the prediabetic group than the nondiabetic group (p= 0.021, p=0.004; respectively). Independent predictors for the primary composite endpoints following the multivariate analysis included SYNTAX score (odds ratio [OR]: 0.912; %95 confidence interval [CI]: 0.832-0.999, p: 0.047), left ventricular ejection fraction (OR: 0.812; %95 CI: 0.753-0.876, p< 0.001), systolic blood pressure (OR: 0.955; %95 CI: 0.927-0.985, p: 0.003) and valuable categorical HbA1c ( 5.7% ≤HbA1c<6. 5% ) (OR: 2.787; %95 CI: 1.091-7.120, p: 0.032). Conclusion: Prediabetes group has been shown to have a higher incidence of the primary composite endpoints than non-diabetes. SYNTAX score, left ventricular ejection fraction, systolic blood pressure, and HbA1c (categorical variable) were found as independent predictors for the primary composite endpoint. Preventive measures in the stage of pre-diabetes might help the prevention of developing CVD.
{"title":"Impact of prediabetes on cardiovascular disease risk in patients with acute myocardial infarctions","authors":"Ö. Karaaslan, Murat Oğuz Özilhan, C. Çöteli, O. Maden","doi":"10.25000/acem.881170","DOIUrl":"https://doi.org/10.25000/acem.881170","url":null,"abstract":"Aim: Prediabetes is known to be associated with increased cardiovascular diseases (CVD) risk and mortality. It has been reported that more than 70% of pre-diabetic patients develop Diabetes Mellitus (DM). In patients with acute myocardial infarction (AMI), diabetes increases a 2 to 4 fold risk of adverse cardiovascular events compared to non-diabetic patients. This morbidity-mortality relationship begins in the progression phase from normal glucose tolerance to diabetes. We evaluated the relationship between the presence of pre-diabetes by using hemoglobin A1c (HbA1c) values and CVD risk in patients presenting with newly diagnosed AMI. Methods: This study was a retrospective, single-centre and we examined consecutive patients who underwent coronary angiography with a diagnosis of AMI at our hospital between March 2019 and September 2020. A total of 332 patients with AMI were enrolled; patients were divided into two groups according to their HbA1c levels: non-diabetic group (HbA1c <5.7%) and pre-diabetic group (5.7% ≤HbA1c <6.05%). The primary composite endpoints were cardiovascular death, myocardial infarction or stroke. Results: Of the 332 patients, 204 (61%) patients had non-diabetic groups, and 128 (39%) patients were between the pre-diabetic groups. During the follow-up period, the primary composite endpoints amounted to 7.4% and 15.6% in the non-diabetes and prediabetes group (p=0.026). The incidences of cardiovascular death and myocardial infarction were significantly higher in the prediabetic group than the nondiabetic group (p= 0.021, p=0.004; respectively). Independent predictors for the primary composite endpoints following the multivariate analysis included SYNTAX score (odds ratio [OR]: 0.912; %95 confidence interval [CI]: 0.832-0.999, p: 0.047), left ventricular ejection fraction (OR: 0.812; %95 CI: 0.753-0.876, p< 0.001), systolic blood pressure (OR: 0.955; %95 CI: 0.927-0.985, p: 0.003) and valuable categorical HbA1c ( 5.7% ≤HbA1c<6. 5% ) (OR: 2.787; %95 CI: 1.091-7.120, p: 0.032). Conclusion: Prediabetes group has been shown to have a higher incidence of the primary composite endpoints than non-diabetes. SYNTAX score, left ventricular ejection fraction, systolic blood pressure, and HbA1c (categorical variable) were found as independent predictors for the primary composite endpoint. Preventive measures in the stage of pre-diabetes might help the prevention of developing CVD.","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76386729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazlı Batar, C. Pak, Rivayet Nükra Tüfekçi̇, Betül Koçak, Rümeysa Özçalkap, Pelin Pak, S. Arıca
{"title":"Evaluation of the nutritional status changes of resident physicians before and during the COVID-19 Pandemic","authors":"Nazlı Batar, C. Pak, Rivayet Nükra Tüfekçi̇, Betül Koçak, Rümeysa Özçalkap, Pelin Pak, S. Arıca","doi":"10.25000/acem.911218","DOIUrl":"https://doi.org/10.25000/acem.911218","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91156589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Myeloprotective and hematoprotective role of kefir on cyclophosphamide toxicity in rats","authors":"Gülay Gözüoğlu, S. Yildiz","doi":"10.25000/acem.903843","DOIUrl":"https://doi.org/10.25000/acem.903843","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"112 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78528972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retrospective Donor Hepatectomy Results in Living Donor Liver Transplant– A Single-Center Experience","authors":"Ramazan Dönmez, O. Andacoglu","doi":"10.25000/acem.929684","DOIUrl":"https://doi.org/10.25000/acem.929684","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89712437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Can Irisin Be Used in the Follow-up of Osteoporosis Treatment?","authors":"E. Demirel, K. Yildiz, K. Çadırcı","doi":"10.25000/acem.909548","DOIUrl":"https://doi.org/10.25000/acem.909548","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74704874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Peripheral Nerves In Patients Receiving Anti -Tnf- α Drug Therapy","authors":"B. Ekinci, H. Yaşar, Y. Arslan","doi":"10.25000/acem.870894","DOIUrl":"https://doi.org/10.25000/acem.870894","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88174213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The change in the frequency of community acquired acute respiratory tract infections in weight loss period after bariatric surgery: An observational case-crossover study. Are those who have had bariatric surgery at risk?","authors":"S. Coskun, C. Kirkil, G. Kırkıl","doi":"10.25000/acem.938844","DOIUrl":"https://doi.org/10.25000/acem.938844","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84362599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Koşmaz, A. Durhan, A. Şenlikçi, M. Süleyman, M. Bostanci, M. R. Pekcici, M. Şeneş, İlknur Alkan Kuşabbi̇, M. Gönültaş, S. Hücümenoğlu, A. M. Barlas, Y. M. Bağ, Can Ersak, Ender Ergüder
{"title":"Evaluation of the Protective Effect of Red Ginseng on Lipid Profile, Endothelial and Oxidative Damage after Splenectomy in Rats","authors":"K. Koşmaz, A. Durhan, A. Şenlikçi, M. Süleyman, M. Bostanci, M. R. Pekcici, M. Şeneş, İlknur Alkan Kuşabbi̇, M. Gönültaş, S. Hücümenoğlu, A. M. Barlas, Y. M. Bağ, Can Ersak, Ender Ergüder","doi":"10.25000/acem.952140","DOIUrl":"https://doi.org/10.25000/acem.952140","url":null,"abstract":"","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90718731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Aim: Proximal femoral nail (PFNA) and hemiarthroplasty are the two most frequently used methods in the surgical treatment of intertrochanteric femur fractures. The study aimed to determine the priority choice for surgical treatment in elderly patients (over 80 years old). Methods: Patients treated for intertrochanteric femur fractures between 2012 and 2017 were retrospectively analyzed. Patients aged 80 years and over who were treated with hemiarthroplasty or PFNA were included in the study. Length of the operation, need for postoperative intensive care, Harris Hip Score, postoperative complications, and mortality rates in the first year were compared. Results: A total of 120 patients with intertrochanteric femur fractures older than 80 years were evaluated. There were 43 patients (35.8) in the hemiarthroplasty group and 77 (64.2) in the PFNA group. No significant differences were found between the two groups in terms of mortality, need for postoperative intensive care, Harris Hip Score, and postoperative complications in the first year. While the median operation time was 45 minutes (IQR 40-50) in the PFNA group, it was 80 minutes (IQR 75-85) in the hemiarthroplasty group (p <0.001). The length of the operation was shorter in the PFNA group. Conclusion: In elderly patients, there were no significant differences between the surgical treatment modalities as hemiarthroplasty and PFNA in treating intertrochanteric fractures considering the postoperative outcomes and mortality rates within the first year. However, shorter operation time might be an advantage of PFNA.
{"title":"Comparison of proximal femoral nail and hemiarthroplasty outcomes in elderly (over 80 years old) patients with intertrochanteric fractures","authors":"A. Şişman, Ş. Şavk, S. Çepni","doi":"10.25000/ACEM.800692","DOIUrl":"https://doi.org/10.25000/ACEM.800692","url":null,"abstract":"Aim: Proximal femoral nail (PFNA) and hemiarthroplasty are the two most frequently used methods in the surgical treatment of intertrochanteric femur fractures. The study aimed to determine the priority choice for surgical treatment in elderly patients (over 80 years old). Methods: Patients treated for intertrochanteric femur fractures between 2012 and 2017 were retrospectively analyzed. Patients aged 80 years and over who were treated with hemiarthroplasty or PFNA were included in the study. Length of the operation, need for postoperative intensive care, Harris Hip Score, postoperative complications, and mortality rates in the first year were compared. Results: A total of 120 patients with intertrochanteric femur fractures older than 80 years were evaluated. There were 43 patients (35.8) in the hemiarthroplasty group and 77 (64.2) in the PFNA group. No significant differences were found between the two groups in terms of mortality, need for postoperative intensive care, Harris Hip Score, and postoperative complications in the first year. While the median operation time was 45 minutes (IQR 40-50) in the PFNA group, it was 80 minutes (IQR 75-85) in the hemiarthroplasty group (p <0.001). The length of the operation was shorter in the PFNA group. Conclusion: In elderly patients, there were no significant differences between the surgical treatment modalities as hemiarthroplasty and PFNA in treating intertrochanteric fractures considering the postoperative outcomes and mortality rates within the first year. However, shorter operation time might be an advantage of PFNA.","PeriodicalId":8220,"journal":{"name":"ARCHIVES OF CLINICAL AND EXPERIMENTAL MEDICINE","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78815718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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