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Normative values of two-point discrimination for lower limb dermatomes in healthy young adults and its correlation with gender and body mass index 健康青壮年下肢皮节两点辨别力的正常值及其与性别、体重指数的相关性
Pub Date : 2023-01-01 DOI: 10.4103/amhs.amhs_65_23
Sanjiv Kumar, Ankita Shetty, Apoorva Nale, ChristinaMary George, Neha Yadav
Background and Aim: Two-point discrimination (TPD) is a useful test for assessing cutaneous sensation. Sensory testing devices for testing TPD values have shown to be valid and reliable in the measurement of the functional sensitivity of the hand and its relativity to touch perception. Evaluation of TPD in the lower extremities is debatable because of dearth of information available in the literature about normative values. The aim of this study is to identify the normative values of TPD of lower limb dermatomes in young, healthy individuals and analyze its relationship with body mass index (BMI) and gender. Materials and Methods: A total of 150 participants of the age group 18–25 undergoing graduation program were included in this study. They underwent TPD test for lower limb (L1 to S2) dermatomes, using a baseline esthesiometer. The Spearman’s ratio test was used to find the relationship between BMI and TPD values. The Mann–Whitney U-test was used to compare TPD values according to gender. Results: The normative value ranged from 1.46 ± 1.27 to 2.61 ± 1.45 in lower limb dermatomes. The minimum value noted was at the S1 dermatome (left) and the maximum at the L2 dermatome (left). In the sidewise analysis of TPD, the median values of both sides were approximately the same. There was a definite correlation (P < 0.05) between female gender and TPD; however, there was no significant correlation between BMI and TPD. Conclusion: This study suggested that women are more perceptive in appreciating TPD values than men. Moreover, TPD values do not vary according to BMI or right and left sides.
背景与目的:两点辨别(Two-point discrimination, TPD)是一种评价皮肤感觉的有效方法。用于测试TPD值的感官测试设备在测量手的功能灵敏度及其与触摸感知的相关性方面已被证明是有效和可靠的。由于文献中缺乏关于规范值的信息,下肢TPD的评估是有争议的。本研究旨在确定年轻健康个体下肢皮体TPD的正常值,并分析其与身体质量指数(BMI)和性别的关系。材料与方法:本研究共纳入150名年龄在18-25岁的应届毕业生。他们使用基线触觉计对下肢(L1至S2)皮节进行TPD测试。采用Spearman比值检验BMI与TPD值之间的关系。采用Mann-Whitney u检验比较不同性别的TPD值。结果:下肢皮节的正常值为1.46±1.27 ~ 2.61±1.45。最小值出现在S1皮节(左),最大值出现在L2皮节(左)。在TPD的横向分析中,两边的中位数大致相同。女性与TPD有一定的相关性(P < 0.05);然而,BMI与TPD之间无显著相关性。结论:本研究提示女性对TPD价值观的感知能力高于男性。此外,TPD值不受BMI或左右两侧的影响。
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引用次数: 0
Autoimmune hemolytic anemia complicating a non-severe SARS-COV2 pneumonia 自身免疫性溶血性贫血并发非严重急性呼吸系统综合征冠状病毒2型肺炎
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_199_22
Y. Motiaa, Youssef Dwassy
COVID-19 has been associated with a spectrum of hematological complications secondary to excessive activation of the immune system. In this article, we report the case of a 64-year-old patient who developed delayed autoimmune hemolytic anemia following a mild severe acute respiratory syndrome-coronavirus-2 infection. We will discuss its pathophysiological, clinical, and biological aspects as well as the clinical management of this complication.
新冠肺炎与一系列继发于免疫系统过度激活的血液系统并发症有关。在这篇文章中,我们报告了一例64岁的患者,他在轻度严重急性呼吸系统综合征冠状病毒2型感染后出现迟发性自身免疫性溶血性贫血。我们将讨论其病理生理、临床和生物学方面,以及这种并发症的临床处理。
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引用次数: 0
Assessment of quality and the utilization of the dental prosthesis and their impact on patient satisfaction 口腔修复体的质量和使用评估及其对患者满意度的影响
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_162_22
Mallika S. Shetty, Hasan Sarfaraz, K. Shenoy
Background and Aim: Assessing patient satisfaction with dental prosthesis is usually difficult if the prosthesis does not fulfill the treatment need of the patient, and in most cases, the professionals' assessment of the prosthesis differs from the patients' perception of quality and treatment outcome. Patient satisfaction is important for the proper utilization of the prosthesis which helps improve the patients' overall quality of life and that remains the professionals' ultimate goal. The aim of this study was to assess the quality and utilization of dental prostheses and their impact on patient satisfaction. Materials and Methods: A cross-sectional survey was conducted on 1312 participants aged 18 years and above using a house-to-house approach among the rural population of Mangalore taluk. The study involved the completion of a predesigned and structured pro forma based on the WHO oral health assessment form. Evaluation of the prosthesis, and its quality was done by the professional. Fisher's exact test and odds ratio were conducted to find the significance of variables. P < 0.05 was considered statistically significant. Results: It was found that the retention and chewing efficiency of the complete denture had a positive comparison that was statistically significant. The retention of the partial denture wearers had a positive correlation between the patient perception and the professional assessment. In fixed partial dentures candidates, there was a statistically significant comparison between their perception and professionals' assessment with regard to hygiene and periodontal health. Conclusion: Most of the completely edentulous patients residing in the rural population of Mangalore taluk are quite satisfied with their prosthesis, whereas the professional assessment revealed that the older denture lacked retention, occlusion, and hygiene.
背景和目的:如果修复体不能满足患者的治疗需求,评估患者对修复体的满意度通常很困难,而且在大多数情况下,专业人员对修复体进行的评估与患者对质量和治疗结果的感知不同。患者满意度对于假体的正确使用至关重要,这有助于提高患者的整体生活质量,也是专业人员的最终目标。本研究的目的是评估假牙的质量和使用情况及其对患者满意度的影响。材料和方法:采用挨家挨户的方法,在芒格洛尔-塔卢克的农村人口中对1312名18岁及以上的参与者进行了横断面调查。该研究涉及根据世界卫生组织口腔健康评估表完成预先设计和结构化的形式。由专业人员对假体及其质量进行评估。通过Fisher精确检验和比值比来寻找变量的显著性。P<0.05被认为具有统计学意义。结果:全口义齿的固位率和咀嚼效率有正相关,具有统计学意义。部分义齿佩戴者的固位与患者的认知和专业评估呈正相关。在固定局部义齿候选者中,他们的感知与专业人员对卫生和牙周健康的评估之间存在统计学上显著的比较。结论:居住在Mangalore taluk农村人口中的大多数完全无牙患者对他们的义齿非常满意,而专业评估显示,老年义齿缺乏固位、咬合和卫生。
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引用次数: 0
Comparing the sensitivity of palm print sign and prayer sign in prediction of difficult intubation in diabetic patients 掌印征与祈祷征预测糖尿病患者插管困难的敏感性比较
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_175_22
Harjot Singh, D. Dwivedi, U. Tandon, V. Bhatnagar, K. Jinjil, S. Tara
Background and Aim: Palm print and prayer signs are manifestations of “limited joint mobility” syndrome caused by long-standing Type I and Type II diabetes mellitus. This study aims at finding out, which of the two signs is more sensitive for the prediction of difficult intubation in type II diabetes mellitus patients. The secondary objective is to correlate the above two signs with the Cormack–Lehane View during direct laryngoscopy and also to determine whether the duration of Type II diabetes mellitus correlates with difficult intubation in isolation. Materials and Methods: A prospective observational study was carried out in a tertiary care hospital. One hundred and fifty patients suffering from Type II diabetes mellitus, undergoing elective general anesthesia with endotracheal intubation, were enrolled in the study. The correlation between Palm print and Prayer sign with Cormack and Lehane grades was studied using the Chi-square test, continuity correction, and Fisher's exact test. The diagnostic efficacy of intubation difficulty for both the signs was assessed by calculating sensitivity, specificity, positive predictive value, negative predictive value, and positive and negative likelihood ratio. Results: The palm print sign was found to be a better indicator of difficult intubation in type II diabetes mellitus patients (P < 0.01). The duration of Type II diabetes mellitus was found to be associated well with difficult intubation (P = 0.007). Conclusion: Palm print sign is the single most important test for predicting difficult intubation in Type II diabetes mellitus patients. Duration of Type II diabetes mellitus itself correlates well with difficult intubation.
背景与目的:掌纹和祈祷征是由长期的1型和2型糖尿病引起的“关节活动受限”综合征的表现。本研究旨在了解这两种体征中哪一种对预测II型糖尿病患者插管困难更为敏感。次要目的是将上述两种体征与直接喉镜检查时的Cormack-Lehane显像相关联,并确定II型糖尿病的持续时间是否与孤立插管困难相关。材料与方法:在某三级医院进行前瞻性观察性研究。150例II型糖尿病患者接受气管插管选择性全身麻醉。采用卡方检验、连续性校正和Fisher精确检验研究掌纹和祈祷符号与Cormack和Lehane等级的相关性。通过计算敏感性、特异性、阳性预测值、阴性预测值、阳性与阴性似然比,评价插管困难对两种体征的诊断效果。结果:掌纹征象是判断2型糖尿病患者插管困难的较好指标(P < 0.01)。2型糖尿病病程与插管困难相关(P = 0.007)。结论:掌纹标志是预测2型糖尿病患者插管困难的最重要指标。2型糖尿病病程本身与插管困难密切相关。
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引用次数: 0
Neurodevelopmental versus functional tics: The state of the art 神经发育与功能性抽搐:最新进展
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_246_22
A. Cavanna, G. Purpura, R. Nacinovich
Tic disorders of neurodevelopmental origin are the most common hyperkinetic disorder in childhood. In cases where both multiple motor tics and at least one vocal tic are present, with a chronic course, a diagnosis of Tourette syndrome can be confirmed. Functional movement disorders are a common type of functional neurological disorder, which has previously been referred to as hysteria and conversion, among other diagnostic labels. Functional tics have long been considered a rarer phenotype of functional movement disorder, compared to functional tremor or functional dystonia. However, during the COVID-19 pandemic, there have been multiple reports worldwide of an unexpected increase in the number of adolescents and young adults presenting with acute-onset functional tics. The differential diagnosis between neurodevelopmental and functional tics can be challenging, but a few demographic and clinical features have proven useful in assisting clinicians. Neurodevelopmental tics present with the gradual onset of simple motor and vocal tics in a rostrocaudal evolution, starting in early childhood, more commonly in boys. Conversely, functional tics often have an abrupt and explosive presentation of severe symptoms, with a later age of onset and a female gender predominance. Moreover, it has been reported that a proportion of patients with functional tics developed their symptoms after being exposed to social media content of influencers displaying similar manifestations. The etiology of the recent “pandemic within the pandemic” is likely to be multifactorial, with increased exposure to social media possibly playing a role alongside the psychosocial impact caused by the COVID-19 pandemic.
神经发育障碍是儿童期最常见的高动力障碍。如果同时存在多发性运动抽搐和至少一次发声抽搐,并伴有慢性病程,则可以确诊为抽动秽语综合征。功能性运动障碍是一种常见的功能性神经障碍,在其他诊断标签中,它以前被称为歇斯底里和转换。长期以来,与功能性震颤或功能性肌张力障碍相比,功能性抽搐被认为是一种罕见的功能性运动障碍表型。然而,在新冠肺炎大流行期间,世界各地有多份报告称,出现急性功能性抽搐的青少年和年轻人数量意外增加。神经发育性抽搐和功能性抽搐之间的鉴别诊断可能具有挑战性,但一些人口统计学和临床特征已被证明对帮助临床医生有用。神经发育性抽动症表现为从儿童早期开始,在喙部发育过程中逐渐出现简单的运动和发声抽动症,更常见于男孩。相反,功能性抽搐通常会突然出现严重症状,发病年龄较晚,女性占主导地位。此外,据报道,一定比例的功能性抽搐患者在接触到具有类似表现的影响者的社交媒体内容后出现症状。最近“大流行中的大流行”的病因可能是多因素的,增加对社交媒体的接触可能与新冠肺炎大流行造成的心理社会影响一起发挥作用。
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引用次数: 3
Role of aminoglycosides in management of ventilator-associated pneumonia caused by Klebsiella pneumoniae: A report from a tertiary care hospital in Jaipur 氨基糖苷类药物在治疗肺炎克雷伯菌引起的呼吸机相关性肺炎中的作用:斋浦尔一家三级护理医院的报告
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_202_22
Shaveta Kataria, E. Rajni, Priyanka Thandi, Mohit Kumar, Garima Kulhari
Background and Aim: Ventilator-associated pneumonia (VAP) is considered as a sub-category of healthcare-associated infections and is associated with high morbidity and mortality. Acinetobacter baumannii complex and Klebsiella pneumoniae (K. pneumoniae) are known to be the most important causes. During the last few decades, polymyxins have represented the most commonly used antimicrobial options against multidrug resistant K. pneumoniae. However, in some cases, aminoglycosides were also found to be effective. Materials and Methods: This retrospective observational study was conducted in a tertiary care hospital in Jaipur from June' 2020 to June' 2021. All endotracheal (ET) aspirate samples from the clinically suspected cases of VAP received in microbiology laboratory were processed using the standard procedures and relevant medical records were reviewed. VITEK 2 automated system was used for the bacterial identification and antimicrobial susceptibility testing. Results: Out of 705 ET aspirate samples received during the study period, 467 were found culture positive. Majority 304 (98.1%) were Gram-negative isolates, while only 6 (1.9%) were Gram-positive. 156;51.3% isolates belonged to A. baumannii complex, followed by K. pneumoniae (73;24.0%). Antimicrobial susceptibility profile of 73 K. pneumoniae isolates to aminoglycosides was noted. Out of 73 isolates, 42 were found to be resistant to both gentamicin and amikacin, 12 isolates were sensitive to both, while 19 isolates showed variable susceptibility. Conclusion: K. pneumoniae is an important causative agent of VAP. While polymyxins have an important role in the management of such cases, aminoglycosides need to be given a careful consideration. They can constitute an effective polymyxin sparing regimen, especially for carbapenem-resistant isolates.
背景和目的:呼吸机相关性肺炎(VAP)被认为是医疗保健相关感染的一个亚类别,具有高发病率和死亡率。已知鲍曼不动杆菌复合体和肺炎克雷伯菌(肺炎克雷伯菌)是最重要的病因。在过去的几十年里,多粘菌素代表了针对多重耐药肺炎克雷伯菌最常用的抗菌选择。然而,在某些情况下,氨基糖苷类也被发现是有效的。材料和方法:本回顾性观察性研究于2020年6月至2021年6月在斋浦尔的一家三级保健医院进行。对微生物实验室收到的临床疑似VAP病例的气管内(ET)抽吸标本按标准程序处理,并查阅相关病历。采用VITEK 2全自动系统进行细菌鉴定和药敏试验。结果:在研究期间收到的705份ET抽吸样本中,有467份培养阳性。革兰阴性菌株304株(98.1%)占多数,革兰阳性菌株6株(1.9%)。鲍曼不动杆菌复合体156株,占51.3%,其次是肺炎克雷伯菌(73株,占24.0%)。观察了73株肺炎克雷伯菌对氨基糖苷类药物的敏感性。在73株分离株中,42株对庆大霉素和阿米卡星均耐药,12株对两种药物均敏感,19株呈可变药敏。结论:肺炎克雷伯菌是VAP的重要病原体。虽然多粘菌素在此类病例的治疗中发挥着重要作用,但氨基糖苷类药物需要慎重考虑。它们可以构成有效的多粘菌素保留方案,特别是对碳青霉烯耐药的分离株。
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引用次数: 0
Academic leadership in the era of curricular and quality transition toward excellence: Frameworks that guide actions needed for facilitating and sustaining change 课程和质量向卓越转变时代的学术领导:促进和维持变革所需的指导行动的框架
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_272_22
T. Chacko
Leadership literature indicates that focus has shifted from “top-down hierarchical” to “leadership everywhere” approach within organizations and this also applies to academic leadership. The context in which the new eco-leadership discourse has emerged, is presented as it is important for academic leaders to be aware that they need to tailor their leadership style and approach to be ready for the 21st century challenges arising from “triple disruptions due to digital and technology revolution, environmental emergency, and rising societal iniquity.” The framework of “leading from within” that has emerged from research on leadership in higher education has been found to be relevant and resonates well with academic leaders in India and so is presented in greater detail. Understanding of different academic leadership frameworks has been used to generate guidelines for academic leaders to use for implementing the changes that they would be expected to make to improve quality and make faculty future-ready.
领导力文献表明,组织内部的重点已经从“自上而下的层级”转向“处处领导力”,这也适用于学术领导力。新的生态领导力话语出现的背景是,学术领袖必须意识到,他们需要调整自己的领导风格和方法,为21世纪的挑战做好准备,这些挑战是由“数字和技术革命、环境紧急情况和日益严重的社会不公造成的三重破坏”引起的。高等教育领导力研究中提出的“内部领导”框架被发现是相关的,并与印度的学术领袖产生了很好的共鸣,因此得到了更详细的介绍。对不同学术领导框架的理解已被用于为学术领导制定指导方针,以用于实施他们期望做出的改变,从而提高质量并为教师的未来做好准备。
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引用次数: 0
An observational study on behavioral problems among the children with epilepsy 癫痫患儿行为问题的观察研究
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_147_22
Banothu Sudhakar, Vura Jyothi, V. Sowmya, P. Kumar, Suneel Bhookya, K. Surender, T. Chandra
Background and Aim: Psychological and biochemical factors are responsible for the behavioral problems in children with epilepsy. A study was conducted to find the prevalence of behavioral problems in children with epilepsy and also to identify the relation among socioeconomic status, age of onset of seizure, and frequency of seizure attacks with the prevalence of behavioral problems. Materials and Methods: It was a prospective observational study conducted in the Department of Pediatrics, Kakatiya Medical College, Warangal. Convenient sampling was considered; the study was conducted for 2 years. Children aged 1–12 years, admitted with epilepsy to pediatric intensive care unit and pediatric wards, were included in this study. Those were having intellectual problems, cerebral palsy, developmental delay, and metabolic and neurodegenerative disorder were excluded from the study. Sociodemographic information was collected from the parents in a standard pro forma. Diagnostic and Statistical Manual of Mental Disorders-oriented scales for different ages were used for the assessment of behavior by translating into regional language. Chi-square test was used; P < 0.05 was considered statistically significant. Results: A total of 112 children were included; male: female ratio was 1.39; 41 (36.6%) children had behavioral problems; age-wise, there was significant difference; gender-wise, there was no significant difference. Attention-deficit/hyperactivity problems were identified to be the predominant. Statistically, there was no significant difference between behavioral problems either with mother education or with parent's socioeconomic status, respectively. When brain imaging was done, normal studies were revealed in 32% of children with behavior problem. Conclusion: Each and every child with epilepsy aged <5 years and frequency of seizure attack >1 time/year needs thorough screening for behavioral problems irrespective of gender and family characteristics.
背景与目的:癫痫患儿的行为问题与心理生化因素有关。本研究旨在了解癫痫患儿行为问题的发生率,以及社会经济地位、癫痫发作年龄、癫痫发作频率与行为问题发生率的关系。材料与方法:本研究是在瓦朗加尔Kakatiya医学院儿科进行的前瞻性观察性研究。考虑方便抽样;这项研究进行了2年。研究对象为1-12岁,因癫痫入住儿科重症监护病房和儿科病房的儿童。那些有智力问题、脑瘫、发育迟缓、代谢和神经退行性疾病的人被排除在研究之外。以标准形式从父母那里收集社会人口统计信息。使用不同年龄的精神障碍诊断与统计手册量表,通过翻译成地区语言进行行为评估。采用卡方检验;P < 0.05为差异有统计学意义。结果:共纳入112例儿童;男女比例为1.39;41例(36.6%)患儿存在行为问题;年龄方面,有显著差异;性别方面,没有显著差异。注意缺陷/多动问题被确定为主要问题。统计上,行为问题与母亲的教育程度和父母的社会经济地位没有显著差异。当进行脑成像时,32%的有行为问题的儿童的研究显示正常。结论:每一个1岁/年的癫痫患儿,不论性别和家庭特征,都需要进行彻底的行为问题筛查。
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引用次数: 0
A study to evaluate the impact of COVID-19 on the mental health of medical students 新冠肺炎疫情对医学生心理健康影响的研究
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_121_22
Shouvik Das, A. Chaudhuri, B. Ray
Background and Aim: The COVID-19 pandemic has imposed huge challenges on medical students and medical educators as they are the frontline workers in health-care management. The present study was conducted to evaluate and compare depression, anxiety, and stress levels and the Impact of Event Scale scores among different phases of undergraduate medical students. Materials and Methods: The present study was conducted online at Burdwan Medical College after taking institutional ethical clearance and informed consent from participants. The Depression, Anxiety, and Stress Scale-21 (DASS-21) scores and the Impact of Event Scale-Revised (IES-R) scores of all phases of MBBS students were evaluated during the first and second waves of the pandemic. Jamovi software was used for statistical analysis and ANOVA was used to compare different groups. Results: There was no significant difference in the DASS-21 scores among all five groups during the first wave, but significant differences were observed in IES-R scores. On post hoc analysis, significant differences were observed in the Intrusion, Avoidance, and Hyperarousal scores between 1st- and 5th-year, 2nd- and 5th-year, and 4th- and 5th-year students. During the second wave, significant differences in DASS-21 and IES-R parameters were observed between the different phases of MBBS students. There were significant positive correlations between IES-R scores and DASS-21 scores among 1st-year students and a significant negative correlation between IES-R scores and anxiety scores among 2nd-year students during the first evaluation. There were significant positive correlations between IES-R scores and DASS-21 scores among 1st-year students and a significant positive correlation between IES-R scores and stress scores among 5th-year students during the second evaluation. Conclusion: Senior batches of MBBS students were more mentally affected by the impact of the pandemic as evaluated by DASS-21 scores and IES-R scores. Levels of depression, stress, and anxiety were also increased during the second wave as compared to the first wave of the present pandemic.
背景与目的:新冠肺炎疫情给医学生和医学教育工作者带来了巨大挑战,因为他们是医疗管理的一线工作者。本研究旨在评估和比较医学本科生不同阶段的抑郁、焦虑和压力水平以及事件量表得分的影响。材料和方法:本研究在获得机构伦理许可和参与者知情同意后,在Burdwan医学院在线进行。在第一波和第二波疫情期间,对MBBS学生所有阶段的抑郁、焦虑和压力量表-21(DAS-21)评分和事件影响量表修订版(IES-R)评分进行了评估。Jamovi软件用于统计分析,ANOVA用于比较不同组。结果:在第一波期间,所有五组的DAS-21评分没有显著差异,但IES-R评分有显著差异。在事后分析中,观察到一年级和五年级、二年级和五年以及四年级和五岁学生的入侵、回避和过度觉醒得分存在显著差异。在第二波中,在MBBS学生的不同阶段,观察到DAS-21和IES-R参数存在显著差异。在第一次评估中,一年级学生的IES-R得分和DAS-21得分之间存在显著的正相关,二年级学生的IES-R得分和焦虑得分之间存在明显的负相关。在第二次评估中,一年级学生的IES-R分数和DAS-21分数之间存在显著的正相关,五年级学生的IES-R分数和压力分数之间存在明显的正相关。结论:根据DAS-21和IES-R评分评估,MBBS高年级学生受疫情影响更大。与当前疫情的第一波相比,第二波疫情期间的抑郁、压力和焦虑水平也有所上升。
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引用次数: 0
Spinal intramedullary tumors 脊髓髓内肿瘤
Pub Date : 2022-07-01 DOI: 10.4103/amhs.amhs_263_22
G. Menon, S. Srinivasan, R. Nair, Ajay Hegde, S. Nair
Intramedullary spinal cord tumors constitute an uncommon group of central nervous system neoplasms which pose considerable diagnostic and management challenges. Often low grade, these tumors have an insidious onset and slow progression, which makes early diagnosis a challenge. Advances in magnetic resonance imaging technology have greatly aided the diagnosis and preoperative planning of intramedullary tumors. Yet, radiological diagnosis can be difficult in the presence of several tumor mimics. The introduction and advancement of microsurgical techniques have made surgery the preferred treatment modality. Timing of intervention, however, is contentious. Eloquence of the surrounding tissue and the unforgiving nature of the spinal cord adds to the surgical challenge. Their treatment and prognosis is largely dependent on tumor histology and patient functionality. Well-demarcated tumors like ependymomas and hemangioblastomas can be resected completely with good outcome. Infiltrative tumors such as high-grade astrocytomas are best managed with biopsies or limited resections. Postoperative deficits can be crippling and the use of intraoperative neurophysiologic monitoring and other adjuncts is mandatory. Subtotal resection carry a high risk of recurrence and gross total resection carries a high risk of operative morbidity. With the availability of newer imaging modalities and intraoperative adjuncts, the earlier pessimistic conservative approach has been replaced by an aggressive surgical approach. This review provides an overview on the entire spectra of spinal intramedullary tumors with particular focus on management strategies.
髓内脊髓肿瘤是一种罕见的中枢神经系统肿瘤,对诊断和治疗提出了相当大的挑战。这些肿瘤通常级别较低,发病隐匿,进展缓慢,这使得早期诊断成为一项挑战。磁共振成像技术的进步极大地帮助了髓内肿瘤的诊断和术前规划。然而,在存在几个肿瘤模拟时,放射诊断可能是困难的。显微外科技术的引进和进步使手术成为首选的治疗方式。然而,干预的时机存在争议。周围组织的复杂性和脊髓的顽固性增加了手术的难度。其治疗和预后在很大程度上取决于肿瘤组织学和患者的功能。像室管膜瘤和血管母细胞瘤这样界限清晰的肿瘤可以完全切除,效果良好。浸润性肿瘤,如高级别星形细胞瘤,最好的治疗方法是活检或有限的切除。术后缺陷可能导致瘫痪,术中神经生理监测和其他辅助手段的使用是强制性的。次全切除有很高的复发风险,而总全切除有很高的手术并发症风险。随着新的成像方式和术中辅助手段的出现,早期悲观的保守入路已被积极的手术入路所取代。本文综述了脊髓髓内肿瘤的整个谱,并特别侧重于治疗策略。
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