Lip prints just like fingerprints follow unique patterns in every individual and are said to vary significantly even within the same family. Lip prints can be recognized from 6th week of intrauterine life and remain unchanged throughout their life. The objective of the present study was to evaluate personal identification through lip print patterns with additional reference to twins and members of the same family. Lips of 75 males, 75 females, and 30 twins were studied in various quadrants. In addition, the pattern in the middle 10 mm of the lower lip was also evaluated to note the pattern distribution and dominance of the type of pattern in different genders. Lip print patterns in five families across three generations (eight members each of the same family) were observed for the existence of inheritance of patterns from their ancestors. Among males and females, the most common pattern in the middle 10 mm of the lower lip is Type III (34.66%) and Type IV (32%), respectively. In the middle 10 mm of the lower lip, 33.33% of twins have similar lip patterns but with differences in its arrangements. The result showed different lip print patterns even in twins and among the members of the same family across three generations, with some similar patterns which suggesting hereditary influences in lip prints. In the present, we can see that lip prints are unique and permanent for every human being even among twins and individuals of the same family.
{"title":"A Study on Uniqueness of Lip Print Patterns: Sexual Dimorphism, Twins, and Across Three Generations","authors":"Qudusia Sultana, Vanessa Fernandes, A. Shetty","doi":"10.4103/amhs.amhs_68_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_68_23","url":null,"abstract":"\u0000 \u0000 \u0000 Lip prints just like fingerprints follow unique patterns in every individual and are said to vary significantly even within the same family. Lip prints can be recognized from 6th week of intrauterine life and remain unchanged throughout their life. The objective of the present study was to evaluate personal identification through lip print patterns with additional reference to twins and members of the same family.\u0000 \u0000 \u0000 \u0000 Lips of 75 males, 75 females, and 30 twins were studied in various quadrants. In addition, the pattern in the middle 10 mm of the lower lip was also evaluated to note the pattern distribution and dominance of the type of pattern in different genders. Lip print patterns in five families across three generations (eight members each of the same family) were observed for the existence of inheritance of patterns from their ancestors.\u0000 \u0000 \u0000 \u0000 Among males and females, the most common pattern in the middle 10 mm of the lower lip is Type III (34.66%) and Type IV (32%), respectively. In the middle 10 mm of the lower lip, 33.33% of twins have similar lip patterns but with differences in its arrangements. The result showed different lip print patterns even in twins and among the members of the same family across three generations, with some similar patterns which suggesting hereditary influences in lip prints.\u0000 \u0000 \u0000 \u0000 In the present, we can see that lip prints are unique and permanent for every human being even among twins and individuals of the same family.\u0000","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gallbladder (GB) neoplasms, although rare, are the most common group of malignant neoplasms of the biliary system and can be missed preoperatively as well as on gross examination. Detection of the type of GB neoplasm and reporting the depth of invasion are important for appropriate management. Histopathologic examination of all cholecystectomy specimens is a must, even if no malignancy is detected radiologically or grossly. We describe a series of eight incidentally detected GB neoplasms and discuss the morphological features, staging, and management along with clinical significance.
{"title":"Histopathological Features of Incidental Neoplasms of the Gallbladder: A Case Series with Review of Literature","authors":"Anish Chandran, Sudha Sharma, Rajni Kaushik, Shailendra Kaushik","doi":"10.4103/amhs.amhs_221_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_221_23","url":null,"abstract":"\u0000 Gallbladder (GB) neoplasms, although rare, are the most common group of malignant neoplasms of the biliary system and can be missed preoperatively as well as on gross examination. Detection of the type of GB neoplasm and reporting the depth of invasion are important for appropriate management. Histopathologic examination of all cholecystectomy specimens is a must, even if no malignancy is detected radiologically or grossly. We describe a series of eight incidentally detected GB neoplasms and discuss the morphological features, staging, and management along with clinical significance.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139789701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09DOI: 10.4103/amhs.amhs_208_23
Bhavna Rani, Saumya P Srivastava, Shafali Thakur
Chat Generative Pre-trained Transformer (ChatGPT), an artificial intelligence-powered chatbot, has received a lot of interest from the academic community since its inception. Health-care sector and higher education has significantly advanced with the use of AI technologies. With the advent of AI technologies, such as ChatGPT, the future of nursing education is poised for significant transformation. In this article, we will explore the potential impact of ChatGPT on nursing education, discussing its benefits, challenges, and implications.
{"title":"Nursing Education in the Age of Chat Generative Pre-Trained Transformer: Current Roles and Future Perspective","authors":"Bhavna Rani, Saumya P Srivastava, Shafali Thakur","doi":"10.4103/amhs.amhs_208_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_208_23","url":null,"abstract":"\u0000 Chat Generative Pre-trained Transformer (ChatGPT), an artificial intelligence-powered chatbot, has received a lot of interest from the academic community since its inception. Health-care sector and higher education has significantly advanced with the use of AI technologies. With the advent of AI technologies, such as ChatGPT, the future of nursing education is poised for significant transformation. In this article, we will explore the potential impact of ChatGPT on nursing education, discussing its benefits, challenges, and implications.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139848159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09DOI: 10.4103/amhs.amhs_158_23
Manoj Kumar Sharma, Sarika Chaudhary
Shin pain is common term used to describe pain and discomfort localized on medial side of the lower leg. A significant association has been discovered between shin pain with distance runners and proving the impact of the physical demands inherent in these physical activities. Contraction of the deep leg flexors during running leads to stress transfer to the tibial fascial attachment, i.e. deep crural fascia at the medial tibial crest which results in fascial dysfunction resulting in shin pain and discomfort. Herein, we report a case of medial tibial shin pain due to fascial dysfunction in a 26-year-old male athletic who was initially treated with physical therapy, and it was failed to ease the patient’s problems completely. Dry needling with fascial winding relieved his symptoms. Dry needling with fascial winding can be a viable therapeutic option for the treatment of nontraumatic medial tibial shin pain.
{"title":"Dry Needling with Fascial Winding in Nontraumatic Medial Tibial Shin Pain","authors":"Manoj Kumar Sharma, Sarika Chaudhary","doi":"10.4103/amhs.amhs_158_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_158_23","url":null,"abstract":"\u0000 Shin pain is common term used to describe pain and discomfort localized on medial side of the lower leg. A significant association has been discovered between shin pain with distance runners and proving the impact of the physical demands inherent in these physical activities. Contraction of the deep leg flexors during running leads to stress transfer to the tibial fascial attachment, i.e. deep crural fascia at the medial tibial crest which results in fascial dysfunction resulting in shin pain and discomfort. Herein, we report a case of medial tibial shin pain due to fascial dysfunction in a 26-year-old male athletic who was initially treated with physical therapy, and it was failed to ease the patient’s problems completely. Dry needling with fascial winding relieved his symptoms. Dry needling with fascial winding can be a viable therapeutic option for the treatment of nontraumatic medial tibial shin pain.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139848551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09DOI: 10.4103/amhs.amhs_208_23
Bhavna Rani, Saumya P Srivastava, Shafali Thakur
Chat Generative Pre-trained Transformer (ChatGPT), an artificial intelligence-powered chatbot, has received a lot of interest from the academic community since its inception. Health-care sector and higher education has significantly advanced with the use of AI technologies. With the advent of AI technologies, such as ChatGPT, the future of nursing education is poised for significant transformation. In this article, we will explore the potential impact of ChatGPT on nursing education, discussing its benefits, challenges, and implications.
{"title":"Nursing Education in the Age of Chat Generative Pre-Trained Transformer: Current Roles and Future Perspective","authors":"Bhavna Rani, Saumya P Srivastava, Shafali Thakur","doi":"10.4103/amhs.amhs_208_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_208_23","url":null,"abstract":"\u0000 Chat Generative Pre-trained Transformer (ChatGPT), an artificial intelligence-powered chatbot, has received a lot of interest from the academic community since its inception. Health-care sector and higher education has significantly advanced with the use of AI technologies. With the advent of AI technologies, such as ChatGPT, the future of nursing education is poised for significant transformation. In this article, we will explore the potential impact of ChatGPT on nursing education, discussing its benefits, challenges, and implications.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139788112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09DOI: 10.4103/amhs.amhs_231_23
S. Naik, T. Revathi
{"title":"Unfamiliar Expectant Father: Indian Obstetrician’s Achilles Heel!","authors":"S. Naik, T. Revathi","doi":"10.4103/amhs.amhs_231_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_231_23","url":null,"abstract":"","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139788295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09DOI: 10.4103/amhs.amhs_225_23
Partik Kaur, V. Pal, Vijay Niranjan, V. Mudgal
Brain-derived neurotrophic factor (BDNF) is a widely studied neurotrophin and is said to be involved in the regulation of many neuronal processes, including neurogenesis, neuronal differentiation, maturation, and survival. Over the years, research has shown a significant variation of serum BDNF levels in schizophrenia with no widespread agreement. Herein, we report on serum BDNF levels in drug-naive patients of schizophrenia in comparison to healthy controls (HC) and correlates of BDNF levels in patients of schizophrenia. The study sample consisted of 120 participants with 60 drug-naive patients of schizophrenia and 60 HC. The blood sample of the study subjects was collected and processed serum was analyzed using an enzyme-linked immunosorbent assay kit for BDNF levels. Clinical assessment of patients was done using the Positive and Negative Syndrome Scale (PANSS) and Montreal Cognitive Assessment. Serum BDNF levels were significantly lower in drug-naive patients of schizophrenia as compared to age and sex-matched HC (P – 0.024). The PANSS total score and positive subscale score were negatively correlated with serum BDNF levels which were statistically significant with P = 0.005 and P = 0.001, respectively. The index study found BDNF levels to be reduced in patients of schizophrenia and BDNF was found to correlate with severity of illness, especially positive symptoms. Thus, developing therapeutic strategies that can activate BDNF signaling may prove beneficial in improving the clinical outcome of schizophrenia.
{"title":"Study of Brain-derived Neurotrophic Factor in Drug-naive Patients with Schizophrenia","authors":"Partik Kaur, V. Pal, Vijay Niranjan, V. Mudgal","doi":"10.4103/amhs.amhs_225_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_225_23","url":null,"abstract":"\u0000 \u0000 \u0000 Brain-derived neurotrophic factor (BDNF) is a widely studied neurotrophin and is said to be involved in the regulation of many neuronal processes, including neurogenesis, neuronal differentiation, maturation, and survival. Over the years, research has shown a significant variation of serum BDNF levels in schizophrenia with no widespread agreement. Herein, we report on serum BDNF levels in drug-naive patients of schizophrenia in comparison to healthy controls (HC) and correlates of BDNF levels in patients of schizophrenia.\u0000 \u0000 \u0000 \u0000 The study sample consisted of 120 participants with 60 drug-naive patients of schizophrenia and 60 HC. The blood sample of the study subjects was collected and processed serum was analyzed using an enzyme-linked immunosorbent assay kit for BDNF levels. Clinical assessment of patients was done using the Positive and Negative Syndrome Scale (PANSS) and Montreal Cognitive Assessment.\u0000 \u0000 \u0000 \u0000 Serum BDNF levels were significantly lower in drug-naive patients of schizophrenia as compared to age and sex-matched HC (P – 0.024). The PANSS total score and positive subscale score were negatively correlated with serum BDNF levels which were statistically significant with P = 0.005 and P = 0.001, respectively.\u0000 \u0000 \u0000 \u0000 The index study found BDNF levels to be reduced in patients of schizophrenia and BDNF was found to correlate with severity of illness, especially positive symptoms. Thus, developing therapeutic strategies that can activate BDNF signaling may prove beneficial in improving the clinical outcome of schizophrenia.\u0000","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139788474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-05DOI: 10.4103/amhs.amhs_220_23
Rajesh Raja Satharla, H. Ahad
The study’s purpose is to improve the quality of care for both local residents and travelers in the Kurnool district by identifying and addressing gaps and barriers. The main objective of the research was to assess the knowledge, attitudes, and practical implementation of travel medicine among primary health-care physicians working in the Kurnool district. The research utilized a descriptive cross-sectional study design. A total of 397 primary care doctors in the Kurnool area participated. Data were collected through a self-administered questionnaire, which covered sociodemographic factors, travel medicine knowledge, attitudes, and practices. The study revealed that a significant portion (around 79.5%) of the participants reported providing travel health advice at some point. The primary source of information on travel medicine for most participants (66%) was the Ministry of Health’s travel guides. However, the study identified a knowledge gap, as 11.4% of individuals were unaware of the origin of typhoid infection. The most common health issues reported during posttrip consultations were diarrhea and respiratory infections. The study’s findings suggested that the general practitioners in the Kurnool district had insufficient knowledge, attitudes, and practices concerning travel medicine. This underscores the need for additional education and training in travel medicine to improve traveler health care and reduce the risk of preventable diseases.
{"title":"Exploring Travel Medicine Perspectives among Primary Care Physicians in Kurnool District: A Comprehensive Study of Knowledge, Attitudes, and Practices","authors":"Rajesh Raja Satharla, H. Ahad","doi":"10.4103/amhs.amhs_220_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_220_23","url":null,"abstract":"\u0000 \u0000 \u0000 The study’s purpose is to improve the quality of care for both local residents and travelers in the Kurnool district by identifying and addressing gaps and barriers. The main objective of the research was to assess the knowledge, attitudes, and practical implementation of travel medicine among primary health-care physicians working in the Kurnool district.\u0000 \u0000 \u0000 \u0000 The research utilized a descriptive cross-sectional study design. A total of 397 primary care doctors in the Kurnool area participated. Data were collected through a self-administered questionnaire, which covered sociodemographic factors, travel medicine knowledge, attitudes, and practices.\u0000 \u0000 \u0000 \u0000 The study revealed that a significant portion (around 79.5%) of the participants reported providing travel health advice at some point. The primary source of information on travel medicine for most participants (66%) was the Ministry of Health’s travel guides. However, the study identified a knowledge gap, as 11.4% of individuals were unaware of the origin of typhoid infection. The most common health issues reported during posttrip consultations were diarrhea and respiratory infections.\u0000 \u0000 \u0000 \u0000 The study’s findings suggested that the general practitioners in the Kurnool district had insufficient knowledge, attitudes, and practices concerning travel medicine. This underscores the need for additional education and training in travel medicine to improve traveler health care and reduce the risk of preventable diseases.\u0000","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-05DOI: 10.4103/amhs.amhs_262_23
Meesa Mehraj, D. Aden, Sabina Khan, N. Ahmad, S. Jetley
Yolk sac tumor (YST) is a germ cell tumor of gonads presenting in children and young adults. It is rare to find metastasis of the YST in effusion fluid. We report a case of a YST in a 17-year-old female diagnosed on cytological examination of ascitic fluid and confirmed histologically after resection as YST. This case not only highlights the rare possibility of metastasis of the YST in ascitic fluid cytology but also emphasizes the diagnostic dilemma it causes in diagnosing such cases in body fluids. Detailed clinical history including the age of the patient, along with serum alpha-fetoprotein (AFP) levels is essential to a make a preoperative diagnosis. Histopathology with AFP immunohistochemistry confirms the diagnosis of such lesions.
{"title":"Yolk Sac Tumor in Ascitic Fluid – Cytodiagnosis of a Rare Case","authors":"Meesa Mehraj, D. Aden, Sabina Khan, N. Ahmad, S. Jetley","doi":"10.4103/amhs.amhs_262_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_262_23","url":null,"abstract":"\u0000 Yolk sac tumor (YST) is a germ cell tumor of gonads presenting in children and young adults. It is rare to find metastasis of the YST in effusion fluid. We report a case of a YST in a 17-year-old female diagnosed on cytological examination of ascitic fluid and confirmed histologically after resection as YST. This case not only highlights the rare possibility of metastasis of the YST in ascitic fluid cytology but also emphasizes the diagnostic dilemma it causes in diagnosing such cases in body fluids. Detailed clinical history including the age of the patient, along with serum alpha-fetoprotein (AFP) levels is essential to a make a preoperative diagnosis. Histopathology with AFP immunohistochemistry confirms the diagnosis of such lesions.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Autoimmune hemolytic anemias (AIHAs) are hemolytic anemias characterized by the production of autoantibodies against surface antigens on red blood cells. Cold agglutinin disease (CAD) is a relatively rare subcategory of AIHA, affecting mainly the middle-aged with anemia often being the presenting symptom. We present a case of a middle-aged female who was admitted for severe anemia under evaluation. A discrepancy in blood grouping was noted when request for blood transfusion was received in a blood bank, owing to autoantibodies interfering in testing. Routine complete blood counts showed temperature-based variations. A detailed workup confirmed a diagnosis of CA type of AIHA. The case reiterates the importance of good interdepartmental coordination between clinicians, laboratory, and blood bank, which helped clinch the diagnosis of CAD through the correlation of clinical findings, blood counts, and immunological and biochemical parameters.
自身免疫性溶血性贫血（AIHA）是一种溶血性贫血，其特征是产生针对红细胞表面抗原的自身抗体。冷凝集素病（Cold agglutinin disease，CAD）是自身免疫性溶血性贫血（AIHA）中相对罕见的一个亚类，主要影响中年人，贫血通常是其主要症状。我们介绍了一例因严重贫血而入院接受评估的中年女性病例。由于自身抗体干扰了检测，她在血库申请输血时发现血型不符。常规全血细胞计数显示出温度变化。经过详细检查，确诊为 CA 型 AIHA。该病例重申了临床医生、实验室和血库之间良好的跨部门协调的重要性，通过临床结果、血细胞计数、免疫学和生化指标的相关性，有助于确诊 CAD。
{"title":"Cold Agglutinin Disease Unfurled in Laboratory and Blood Bank: A Little Poignant Observation Can Speak a Lot!","authors":"Archana Shetty, Gurudatta Murthy, Bharadwaj Golithadka","doi":"10.4103/amhs.amhs_204_23","DOIUrl":"https://doi.org/10.4103/amhs.amhs_204_23","url":null,"abstract":"\u0000 Autoimmune hemolytic anemias (AIHAs) are hemolytic anemias characterized by the production of autoantibodies against surface antigens on red blood cells. Cold agglutinin disease (CAD) is a relatively rare subcategory of AIHA, affecting mainly the middle-aged with anemia often being the presenting symptom. We present a case of a middle-aged female who was admitted for severe anemia under evaluation. A discrepancy in blood grouping was noted when request for blood transfusion was received in a blood bank, owing to autoantibodies interfering in testing. Routine complete blood counts showed temperature-based variations. A detailed workup confirmed a diagnosis of CA type of AIHA. The case reiterates the importance of good interdepartmental coordination between clinicians, laboratory, and blood bank, which helped clinch the diagnosis of CAD through the correlation of clinical findings, blood counts, and immunological and biochemical parameters.","PeriodicalId":8296,"journal":{"name":"Archives of Medicine and Health Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139629615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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