Pub Date : 2025-11-20DOI: 10.1016/j.arbres.2025.11.006
Alyson W Wong, Christopher J Ryerson
{"title":"Defining Progressive Pulmonary Fibrosis: Implications for Clinical Trials, Guidelines, and Patient Care.","authors":"Alyson W Wong, Christopher J Ryerson","doi":"10.1016/j.arbres.2025.11.006","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.006","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145660098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-20DOI: 10.1016/j.arbres.2025.11.005
Jacopo Cefalo, Francesco Varone, Fabrizio Luppi, Paolo Cameli, Stefania Cerri, Mariangela Valentina Puci, Alessia Martini, Giovanni Franco, Umberto Zanini, Tommaso Pianigiani, Athina Patsoura, Luca Richeldi, Elena Bargagli, Giovanni Sotgiu, Michele Mondoni
{"title":"Impact of Dosing on Functional and Clinical Outcomes of Patients With Progressive Pulmonary Fibrosis Treated With Nintedanib: Data From a Real-World, Multicentric, Italian Study.","authors":"Jacopo Cefalo, Francesco Varone, Fabrizio Luppi, Paolo Cameli, Stefania Cerri, Mariangela Valentina Puci, Alessia Martini, Giovanni Franco, Umberto Zanini, Tommaso Pianigiani, Athina Patsoura, Luca Richeldi, Elena Bargagli, Giovanni Sotgiu, Michele Mondoni","doi":"10.1016/j.arbres.2025.11.005","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.005","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145666843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.002
Winnifer Briceño, Juan Manuel Velasco, Ana Castillo, Ignacio Jara, Laura Lago, Edwin Yong, Gema Díaz, Gregory Piazza, Behnood Bikdeli, David Jiménez
Background: In patients with acute symptomatic pulmonary embolism (PE), embolic burden has an uncertain prognostic significance.
Methods: We performed a meta-analysis of studies including patients with PE to assess the prevalence and prognostic relevance of central PE (i.e., saddle or main pulmonary emboli) for short-term death and other adverse outcome events. A random-effects model was used to pool study results, and I2 testing was used to test for heterogeneity.
Results: Data from 28 studies (205,877 patients) were included in the analysis. Of the 26 studies with 205,410 participants that enrolled consecutive patients with PE, 7748 (3.8%) had central PE. Though there was no statistically significant difference between central and noncentral PE for odds of short-term all-cause mortality (odds ratio [OR] 1.19; 95% confidence interval [CI], 0.91-1.55), central PE had a significant association with short-term PE-related deterioration or death (OR, 2.47; 95% CI, 1.44-4.25). Results from 9 studies with 4325 PE patients that had available data showed that central PE had a significant association with the odds of short-term PE-related mortality (OR, 1.77; 95% CI, 1.22-2.55). Results were consistent for prospective (OR, 1.67; 95% CI, 1.21-2.32), and studies that only enrolled stable patients (OR, 1.42; 95% CI, 1.06-1.92).
Conclusions: Central PE was an uncommon finding in unselected patients diagnosed with PE. While central thrombus did not have an association with increased risk of all-cause mortality, it was significantly associated with an increased risk of PE-related deterioration and death short after diagnosis.
{"title":"Prevalence and Prognostic Relevance of Central Pulmonary Embolism: Systematic Review and Meta-Analysis.","authors":"Winnifer Briceño, Juan Manuel Velasco, Ana Castillo, Ignacio Jara, Laura Lago, Edwin Yong, Gema Díaz, Gregory Piazza, Behnood Bikdeli, David Jiménez","doi":"10.1016/j.arbres.2025.11.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.002","url":null,"abstract":"<p><strong>Background: </strong>In patients with acute symptomatic pulmonary embolism (PE), embolic burden has an uncertain prognostic significance.</p><p><strong>Methods: </strong>We performed a meta-analysis of studies including patients with PE to assess the prevalence and prognostic relevance of central PE (i.e., saddle or main pulmonary emboli) for short-term death and other adverse outcome events. A random-effects model was used to pool study results, and I<sup>2</sup> testing was used to test for heterogeneity.</p><p><strong>Results: </strong>Data from 28 studies (205,877 patients) were included in the analysis. Of the 26 studies with 205,410 participants that enrolled consecutive patients with PE, 7748 (3.8%) had central PE. Though there was no statistically significant difference between central and noncentral PE for odds of short-term all-cause mortality (odds ratio [OR] 1.19; 95% confidence interval [CI], 0.91-1.55), central PE had a significant association with short-term PE-related deterioration or death (OR, 2.47; 95% CI, 1.44-4.25). Results from 9 studies with 4325 PE patients that had available data showed that central PE had a significant association with the odds of short-term PE-related mortality (OR, 1.77; 95% CI, 1.22-2.55). Results were consistent for prospective (OR, 1.67; 95% CI, 1.21-2.32), and studies that only enrolled stable patients (OR, 1.42; 95% CI, 1.06-1.92).</p><p><strong>Conclusions: </strong>Central PE was an uncommon finding in unselected patients diagnosed with PE. While central thrombus did not have an association with increased risk of all-cause mortality, it was significantly associated with an increased risk of PE-related deterioration and death short after diagnosis.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145660050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.004
Javier Sayas Catalán, Maxime Patout
{"title":"Breathing on the Bench: Are We Over-simulating or Underestimating NIV Realities? A PRO/CON Debate.","authors":"Javier Sayas Catalán, Maxime Patout","doi":"10.1016/j.arbres.2025.11.004","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.004","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-14DOI: 10.1016/j.arbres.2025.11.003
Francisco Javier Álvarez-Gutiérrez, Francisco Casas-Maldonado, José Valverde-Molina
{"title":"News From the Severe Asthma Consensus 2025 Review.","authors":"Francisco Javier Álvarez-Gutiérrez, Francisco Casas-Maldonado, José Valverde-Molina","doi":"10.1016/j.arbres.2025.11.003","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.11.003","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-04DOI: 10.1016/j.arbres.2025.10.017
Aida Monge, Ane Martínez-De Las Fuentes, Javier Burgos, Cristina Pou, Joel-Suresh Lakhani, Annie Navarro, Rosa Abril Castañon, Eduardo J García-Urrestarazu, Alicia Sayés, Ana Belén Alcaide, Marta Erro, Beatriz Raboso Moreno, Anna Sánchez-Cucó, Sally Santisteve, Iván D Benítez, Anna Moncusí-Moix, Esther Gracia-Lavedan, Carlos Manzano, Arturo Morales, Ferrán Barbé, Guillermo Suarez-Cuartín, David de la Rosa-Carrillo, Juan P de-Torres, Jessica González
{"title":"Combining Airway Clearance Techniques and Inhaled Antibiotics in Chronic Bronchial Infection: Real-World Evidence of Exacerbation Reduction (INBREATHING Study).","authors":"Aida Monge, Ane Martínez-De Las Fuentes, Javier Burgos, Cristina Pou, Joel-Suresh Lakhani, Annie Navarro, Rosa Abril Castañon, Eduardo J García-Urrestarazu, Alicia Sayés, Ana Belén Alcaide, Marta Erro, Beatriz Raboso Moreno, Anna Sánchez-Cucó, Sally Santisteve, Iván D Benítez, Anna Moncusí-Moix, Esther Gracia-Lavedan, Carlos Manzano, Arturo Morales, Ferrán Barbé, Guillermo Suarez-Cuartín, David de la Rosa-Carrillo, Juan P de-Torres, Jessica González","doi":"10.1016/j.arbres.2025.10.017","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.10.017","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145548000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-04DOI: 10.1016/j.arbres.2025.10.018
Paola Ordóñez Gómez, María Dolores Miñana, Carlos García-Ballesteros, Jaime Signes-Costa, Juan José Soler-Cataluña
{"title":"Immune Gene Polymorphisms and Lung Cancer Risk in Chronic Obstructive Pulmonary Disease with Emphysema.","authors":"Paola Ordóñez Gómez, María Dolores Miñana, Carlos García-Ballesteros, Jaime Signes-Costa, Juan José Soler-Cataluña","doi":"10.1016/j.arbres.2025.10.018","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.10.018","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145628262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-04DOI: 10.1016/j.arbres.2025.10.016
Adriano D S Targa, Manuel Sánchez-de-la-Torre, Ferran Barbé
{"title":"A Timely Call to Understand the Link Between Obstructive Sleep Apnoea and Circadian Disruption.","authors":"Adriano D S Targa, Manuel Sánchez-de-la-Torre, Ferran Barbé","doi":"10.1016/j.arbres.2025.10.016","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.10.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2025-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145522814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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