Pub Date : 2026-01-15DOI: 10.1016/j.arbres.2026.01.003
Luis Gorospe, Ana Villanueva-Campos, Luis Carlos Lomanto-Navarro
{"title":"Pulmonary Embolism Secondary to Partially Thrombosed Aneurysm of the Left Innominate Vein: A Complication of a Narrow Aortosternal Space?","authors":"Luis Gorospe, Ana Villanueva-Campos, Luis Carlos Lomanto-Navarro","doi":"10.1016/j.arbres.2026.01.003","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.01.003","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-15DOI: 10.1016/j.arbres.2026.01.004
Winnifer Briceño, David Jiménez
{"title":"Reply to \"Saddle Pulmonary Embolism in Hemodynamically Stable Patients: Clinical Implications and Unresolved Questions\".","authors":"Winnifer Briceño, David Jiménez","doi":"10.1016/j.arbres.2026.01.004","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.01.004","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-15DOI: 10.1016/j.arbres.2025.10.021
José Antonio Caminero, Luís Anibarro, Eva Tabernero, Fernando Alcaide, Guillermo Pérez-Mendoza, Joan-Pau Millet, Remedio Guna, Maria-Luiza de Souza-Galvão, Paula López-Roa, Adrián Sánchez-Montalvá, José A Gullón-Blanco, Verónica González-Galán
All strategies on the pathway to tuberculosis (TB) elimination prioritise, among other measures, addressing tuberculosis infection (TBI), particularly the identification of individuals and population groups who should be candidates for tuberculosis preventive treatment (TPT). In Spain, a TBI test is required before recommending TPT. An interferon-gamma release assay (IGRA) is preferred over the tuberculin skin test (TST), although the latter may be used in settings where IGRAs are not available or when deemed necessary to increase diagnostic sensitivity. On the other hand, new skin tests employing specific antigens (TBST) may play a key role. As a general principle, screening for TBI should include all individuals at high risk for progressing from TBI to TB, as described in this guideline, prioritising pulmonary TB contacts, people living with HIV, immunocompromised individuals and those in other situations associated with an elevated risk of developing TB. Once TBI has been diagnosed in these high-risk groups, the algorithm set out in this guideline should be applied to rule out TB disease. Once TB has been excluded, TPT should be recommended. The preferred regimen is daily isoniazid (H) plus rifampicin (R) for 3 months (3HR). However, once rifapentine becomes available in Spain, both the 1-month daily (1HP) and the 3-month weekly (3HP) regimens combining H and rifapentine (P) may also be used. Finally, measures must be taken to ensure adherence to TPT and to monitor and manage potential drug-related adverse effects.
{"title":"Recommendations on the Diagnosis and Treatment of Tuberculosis Infection: SEPAR/SEIMC/Spanish Ministry of Health Consensus Statement.","authors":"José Antonio Caminero, Luís Anibarro, Eva Tabernero, Fernando Alcaide, Guillermo Pérez-Mendoza, Joan-Pau Millet, Remedio Guna, Maria-Luiza de Souza-Galvão, Paula López-Roa, Adrián Sánchez-Montalvá, José A Gullón-Blanco, Verónica González-Galán","doi":"10.1016/j.arbres.2025.10.021","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.10.021","url":null,"abstract":"<p><p>All strategies on the pathway to tuberculosis (TB) elimination prioritise, among other measures, addressing tuberculosis infection (TBI), particularly the identification of individuals and population groups who should be candidates for tuberculosis preventive treatment (TPT). In Spain, a TBI test is required before recommending TPT. An interferon-gamma release assay (IGRA) is preferred over the tuberculin skin test (TST), although the latter may be used in settings where IGRAs are not available or when deemed necessary to increase diagnostic sensitivity. On the other hand, new skin tests employing specific antigens (TBST) may play a key role. As a general principle, screening for TBI should include all individuals at high risk for progressing from TBI to TB, as described in this guideline, prioritising pulmonary TB contacts, people living with HIV, immunocompromised individuals and those in other situations associated with an elevated risk of developing TB. Once TBI has been diagnosed in these high-risk groups, the algorithm set out in this guideline should be applied to rule out TB disease. Once TB has been excluded, TPT should be recommended. The preferred regimen is daily isoniazid (H) plus rifampicin (R) for 3 months (3HR). However, once rifapentine becomes available in Spain, both the 1-month daily (1HP) and the 3-month weekly (3HP) regimens combining H and rifapentine (P) may also be used. Finally, measures must be taken to ensure adherence to TPT and to monitor and manage potential drug-related adverse effects.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145987618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-15DOI: 10.1016/j.arbres.2026.01.002
Lei Qi, Paul R Allyn Iii, Gregory A Fishbein
{"title":"A 73-Year-Old Woman With a 7-Year History of a Slowly Growing Lung Mass and Hemoptysis Mimicking Malignancy.","authors":"Lei Qi, Paul R Allyn Iii, Gregory A Fishbein","doi":"10.1016/j.arbres.2026.01.002","DOIUrl":"https://doi.org/10.1016/j.arbres.2026.01.002","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146096738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.013
Ane Lopez-Gonzalez, Robson Aparecido Prudente, Cristina Aljama, Cristina Esquinas, Maria Torres-Duran, Alice M Turner, Hanan Tanash, Carlota Rodríguez-García, Angelo Corsico, Eva Bartošovská, Catarina Guimarães, José Luis López-Campos, Jens-Ulrik Stæhr Jensen, José María Hernández-Pérez, Christian F Clarenbach, Kenneth R Chapman, Juan Luis Rodríguez-Hermosa, Maria Sucena, Marc Miravitlles, Miriam Barrecheguren
{"title":"Routine Blood Biomarkers in Patients With the PI*SZ Genotype of Alpha-1 Antitrypsin Deficiency: Data From the EARCO Registry.","authors":"Ane Lopez-Gonzalez, Robson Aparecido Prudente, Cristina Aljama, Cristina Esquinas, Maria Torres-Duran, Alice M Turner, Hanan Tanash, Carlota Rodríguez-García, Angelo Corsico, Eva Bartošovská, Catarina Guimarães, José Luis López-Campos, Jens-Ulrik Stæhr Jensen, José María Hernández-Pérez, Christian F Clarenbach, Kenneth R Chapman, Juan Luis Rodríguez-Hermosa, Maria Sucena, Marc Miravitlles, Miriam Barrecheguren","doi":"10.1016/j.arbres.2025.12.013","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.009
Peter J Mazzone
{"title":"The Future of Lung Cancer Screening.","authors":"Peter J Mazzone","doi":"10.1016/j.arbres.2025.12.009","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.009","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146043674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.010
Ana Morales-Tirado, Enrique Blitz-Castro, Ana Tabares-González, Celia Gascón-Galindo, Saioa Vicente-Santamaría, Carmen Luna-Paredes, Enrique Salcedo-Lobato, Simon Boutry, Adelaida Lamas-Ferreiro
Background: Newborn blood spot screening (NBS) for cystic fibrosis (CF) increasingly identifies infants with inconclusive results, classified as CF screen-positive inconclusive diagnosis (CFSPID). However, long-term outcome data remain limited.
Objective: To analyze the clinical and biochemical course of children with CFSPID.
Methods: We conducted a bi-center observational cohort study including all children designated as CFSPID through the Madrid NBS program from July 2009 to June 2024. Follow-up assessments included serial sweat chloride (SC) testing, respiratory and gastrointestinal (GI) evaluations, spirometry from age 5 or older, nasopharyngeal cultures, and fecal elastase measurements.
Results: A total of 100 children were enrolled. After a median follow-up of 3.59 years [IQR, 1.73-5.43], 25% were reclassified as unaffected carriers following CFTR variant reinterpretation. The remaining 75 were categorized into 3 genotype groups: 66 with CF-causing (CFc)/Variant of Varying Clinical Consequence (VVCC), 4 with VVCC/VVCC, and 5 with CFc/Variant of Uncertain Significance (VUS). By the end of follow-up, 42.67% developed at least 1 intermediate or positive SC value. Three children (4%), all carrying the CFc/VVCC genotype, converted to cystic fibrosis (mean age at conversion, 4.23 years), and 1 child (1.3%) developed a CFTR-related disorder. Clinical signs were mild, with normal spirometry and full pancreatic sufficiency. No Pseudomonas aeruginosa isolates were detected.
Conclusions: Conversion from CFSPID to CF was rare (4%), but abnormal SC values were frequent (42.67%), supporting the need for structured, long-term monitoring. Continued follow-up in specialized CF centers is essential for early detection of disease progression.
{"title":"Long-term Outcomes of Pediatric CFSPID: A 15-Year Clinical and Genomic Study Across Newborn Screening Cystic Fibrosis Units.","authors":"Ana Morales-Tirado, Enrique Blitz-Castro, Ana Tabares-González, Celia Gascón-Galindo, Saioa Vicente-Santamaría, Carmen Luna-Paredes, Enrique Salcedo-Lobato, Simon Boutry, Adelaida Lamas-Ferreiro","doi":"10.1016/j.arbres.2025.12.010","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.010","url":null,"abstract":"<p><strong>Background: </strong>Newborn blood spot screening (NBS) for cystic fibrosis (CF) increasingly identifies infants with inconclusive results, classified as CF screen-positive inconclusive diagnosis (CFSPID). However, long-term outcome data remain limited.</p><p><strong>Objective: </strong>To analyze the clinical and biochemical course of children with CFSPID.</p><p><strong>Methods: </strong>We conducted a bi-center observational cohort study including all children designated as CFSPID through the Madrid NBS program from July 2009 to June 2024. Follow-up assessments included serial sweat chloride (SC) testing, respiratory and gastrointestinal (GI) evaluations, spirometry from age 5 or older, nasopharyngeal cultures, and fecal elastase measurements.</p><p><strong>Results: </strong>A total of 100 children were enrolled. After a median follow-up of 3.59 years [IQR, 1.73-5.43], 25% were reclassified as unaffected carriers following CFTR variant reinterpretation. The remaining 75 were categorized into 3 genotype groups: 66 with CF-causing (CFc)/Variant of Varying Clinical Consequence (VVCC), 4 with VVCC/VVCC, and 5 with CFc/Variant of Uncertain Significance (VUS). By the end of follow-up, 42.67% developed at least 1 intermediate or positive SC value. Three children (4%), all carrying the CFc/VVCC genotype, converted to cystic fibrosis (mean age at conversion, 4.23 years), and 1 child (1.3%) developed a CFTR-related disorder. Clinical signs were mild, with normal spirometry and full pancreatic sufficiency. No Pseudomonas aeruginosa isolates were detected.</p><p><strong>Conclusions: </strong>Conversion from CFSPID to CF was rare (4%), but abnormal SC values were frequent (42.67%), supporting the need for structured, long-term monitoring. Continued follow-up in specialized CF centers is essential for early detection of disease progression.</p>","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146043717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.011
Manuela Herrera, Juan Jose Zapata, Mireia Dalmases
{"title":"Central Sleep Apnea in Multiple Sclerosis: An Underrecognized Comorbidity.","authors":"Manuela Herrera, Juan Jose Zapata, Mireia Dalmases","doi":"10.1016/j.arbres.2025.12.011","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.011","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.012
María López-Paraja, Ignacio Donate-Velasco, Luis Gorospe
{"title":"Two for One: Percutaneous CT-Guided Drainage of a Lung Abscess and Parapneumonic Effusion in a Single Procedure.","authors":"María López-Paraja, Ignacio Donate-Velasco, Luis Gorospe","doi":"10.1016/j.arbres.2025.12.012","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.012","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146028162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-01-09DOI: 10.1016/j.arbres.2025.12.014
Ahmet Büber, Fatih Can Yüksel, Gökhan Polat
{"title":"Anomalous Loop Formation of the Left Brachiocephalic Vein: Imaging Findings of an Extremely Rare Congenital Venous Anomaly.","authors":"Ahmet Büber, Fatih Can Yüksel, Gökhan Polat","doi":"10.1016/j.arbres.2025.12.014","DOIUrl":"https://doi.org/10.1016/j.arbres.2025.12.014","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":" ","pages":""},"PeriodicalIF":9.2,"publicationDate":"2026-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146040229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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