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Etiotypes in COPD: a pro/con debate 慢性阻塞性肺病的病因。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.08.002
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引用次数: 0
Acute Fibrinous and Organizing Pneumonia Associated With Mycobacterium tuberculosis 与结核分枝杆菌相关的急性纤维蛋白性和组织性肺炎
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.07.021
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引用次数: 0
Mycobacterium branderi Diagnosed by CryoEBUS. A New Tool for Infection Diagnosis? 用低温电子串联技术诊断烙印分枝杆菌。感染诊断的新工具?
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.06.012
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引用次数: 0
Incidence and Determinants of COVID-19 Among People Who Smoke (2018–2021): Findings From the ITC EUREST-PLUS Spain Surveys 吸烟人群中 COVID-19 的发生率和决定因素(2018-2021 年):ITC EUREST-PLUS 西班牙调查的结果
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.05.037

Objective

To estimate the cumulative incidence of COVID-19 and its determinants among a nationally representative sample of adults from Spain who smoke.

Methods

This is a prospective cohort study that uses data from two waves (Wave 2 in 2018 and Wave 3 in 2021) of the ITC EUREST-PLUS Spain Survey. At baseline (Wave 1 in 2016), all respondents were adults (aged ≥18) who smoked. In total, 1008 respondents participated in Wave 2, and 570 out of 888 eligible participants were followed up in Wave 3 (64.2%). We estimated the cumulative incidence and the relative risk of COVID-19 (RR) and 95% confidence intervals (CI) during follow-up using self-reported information on sociodemographic, smoking-related and health-related characteristics and identified associated factors using multivariable Poisson models with robust variance adjusted for the independent variables.

Results

The overall cumulative incidence of self-reported COVID-19 was 5.9% (95% CI: 3.9–8.0%), with no significant differences between males (6.3%; 95% CI: 3.6–9.0%) and females (5.6%; 95% CI: 3.2–8.0%). After adjusting for age, sex, and educational level, COVID-19 incidence was positively associated with moderate nicotine dependence (RR: 2.37; 95% CI: 1.04–5.40) and negatively associated with having a partner who smoked (RR: 0.12; 95% CI: 0.03–0.42), and having friends but not a partner who smoked (RR: 0.28; 95% CI: 0.14–0.56).

Conclusion

The correlates of having had COVID-19 among people who smoke should be considered when tailoring information and targeted non-pharmacological preventive measures.
方法这是一项前瞻性队列研究,使用的数据来自 ITC EUREST-PLUS 西班牙调查的两个波次(2018 年第 2 波次和 2021 年第 3 波次)。基线时(2016 年第 1 波),所有受访者均为吸烟的成年人(年龄≥18 岁)。共有 1008 名受访者参与了第 2 次调查,888 名符合条件的参与者中有 570 人接受了第 3 次调查的随访(64.2%)。我们利用自我报告的社会人口学特征、吸烟相关特征和健康相关特征信息,估算了随访期间COVID-19的累积发病率和相对风险(RR)及95%置信区间(CI),并利用多变量泊松模型确定了相关因素,对自变量进行了稳健方差调整。结果 自我报告的 COVID-19 总累积发病率为 5.9%(95% CI:3.9-8.0%),男性(6.3%;95% CI:3.6-9.0%)和女性(5.6%;95% CI:3.2-8.0%)之间无显著差异。在对年龄、性别和教育程度进行调整后,COVID-19 的发生率与中度尼古丁依赖呈正相关(RR:2.37;95% CI:1.04-5.40),而与有吸烟伴侣呈负相关(RR:0.12;95% CI:0.03-0.42)。结论在定制信息和有针对性的非药物预防措施时,应考虑吸烟人群中 COVID-19 的相关性。
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引用次数: 0
Stoma Stent in a Tracheotomy Decannulation Process. Experience With Patients on Prolonged Mechanical Ventilation 气管切开术中的造口支架。长期机械通气患者的经验
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.07.004
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引用次数: 0
Comparison of 5-Year Survival and Disease Recurrence After Trisegmentectomy or Left Upper Lobectomy: A Propensity Score Analysis of the National GEVATS Database 三段切除术或左上肺叶切除术后 5 年生存率和疾病复发率的比较:全国 GEVATS 数据库的倾向得分分析
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-11-01 DOI: 10.1016/j.arbres.2024.05.032

Introduction

Trisegmentectomy, or resection of the upper subdivision of the left upper lobe with preservation of the lingula, is considered by some authors to be equivalent to right upper lobectomy with middle lobe preservation.
Our objective was to compare survival and recurrence after trisegmentectomy versus left upper lobectomy procedures registered in the Spanish Video-Assisted Thoracic Surgery group (GEVATS) database.

Methods

We compared mortality, survival and recurrence in patients with left upper lobectomy or trisegmentectomy after propensity score matching for the following variables: age, smoking habit, tumor size, histologic type, radiological density of tumor, surgical access, forced expiratory volume in one second, diffusing capacity of the lungs for carbon monoxide, hypertension, chronic heart failure, ischemic heart disease, arrhythmia, stroke, peripheral vascular disease, diabetes and pre-surgery nodal status by positron emission tomography/computed tomography.

Results

A total of 540 left upper lobectomies and 83 trisegmentectomies were registered in the GEVATS database. After propensity score matching, 134 left upper lobectomies and 67 trisegmentectomies were selected. Survival outcomes were similar, but differences were found for recurrence (21.5% for trisegmentectomies vs. 35.4% for left upper lobectomies, p = 0.05). Moreover, the recurrence patterns differed, with the lobectomy group showing a greater tendency to distant dissemination.

Conclusions

Trisegmentectomy and left upper lobectomy show similar 5-year survival rates. In our database, recurrence after trisegmentectomy was lower than after left upper lobectomy, while the recurrence pattern differed among the 2 surgical approaches, with a greater tendency to distant metastasis after left upper lobectomy.
我们的目的是比较西班牙视频辅助胸腔镜手术组(GEVATS)数据库中登记的三段切除术和左上肺叶切除术后的生存率和复发率。方法我们比较了左上肺叶切除术和三段切除术患者的死亡率、生存率和复发率,并对以下变量进行了倾向评分匹配:年龄、吸烟习惯、肿瘤大小、组织学类型、肿瘤放射学密度、手术入路、一秒钟用力呼气容积、肺部对一氧化碳的弥散能力、高血压、慢性心力衰竭、缺血性心脏病、心律失常、中风、外周血管疾病、糖尿病以及手术前的正电子发射断层扫描/计算机断层扫描结节状态。结果 GEVATS数据库共登记了540例左上肺叶切除术和83例三叶切除术。经过倾向评分匹配后,选出了134例左上肺叶切除术和67例三叶切除术。存活率结果相似,但在复发率方面存在差异(三段切除术为21.5%,左上肺叶切除术为35.4%,P = 0.05)。结论三段切除术和左上肺叶切除术的5年生存率相似。在我们的数据库中,三段切除术后的复发率低于左上肺叶切除术后,而两种手术方式的复发模式不同,左上肺叶切除术后更倾向于远处转移。
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引用次数: 0
New Phenotypes of Pulmonary Hypertension Associated With Respiratory Diseases: Towards Traits to Treat. 与呼吸系统疾病相关的肺动脉高压新表型:治疗肺动脉高压的特征。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-10-22 DOI: 10.1016/j.arbres.2024.10.008
Manuel López Meseguer, Berta Sáez Giménez
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引用次数: 0
Pulmonary Artery Pseudoaneurysm: A Rare Complication After Suction Thrombectomy. 肺动脉假性动脉瘤:抽吸血栓切除术后的罕见并发症。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-10-22 DOI: 10.1016/j.arbres.2024.10.004
Madeline Watson, Narat Srivali
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引用次数: 0
Effect of the Antibody-mediated Immune Responses on COPD, Asthma, and Lung Function: A Mendelian Randomization Study. 抗体介导的免疫反应对慢性阻塞性肺病、哮喘和肺功能的影响:孟德尔随机化研究》。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-10-22 DOI: 10.1016/j.arbres.2024.10.003
Xu Guixing, Liu Yilin, Fan Huaying, Liang Fanrong, Li Dehua

Introduction: The precise cause of antibody-mediated immune responses on chronic obstructive pulmonary disease (COPD), asthma, and lung function remains unclear. We characterized the relationship between antibody-mediated immune responses to COPD, asthma, and lung function, ultimately achieve the prevention or treatment.

Methods: We obtained summary data from published genome-wide association studies, including antibody-mediated immune responses, COPD, asthma, forced expiratory volume in the first second (FEV1), forced expiratory volume (FVC), and FEV1/FVC. Bidirectional two-sample mendelian randomization (MR) analysis was used to assess causal relationships of antibody-mediated immune responses, COPD, asthma, FEV1, FVC, and FEV1/FVC.

Results: A total of 20 antibody-mediated immune responses were identified have a significant causal effect on COPD, asthma, FEV1, and FVC, with six exhibiting reverse causality. Importantly, the results of the five MR analyses were almost identical with respect to the causal effect of anti-polyomavirus 2 IgG seropositivity and varicella zoster virus glycoprotein E and I antibody levels on the risk of COPD, asthma, FEV1, and FVC.

Conclusions: This study contributes to existing knowledge by investigating the causal relationship between antibody-mediated immune responses and respiratory conditions, including COPD, asthma, and lung function, using a two-sample MR design. The key findings can aid in identifying individuals at risk of these conditions and facilitate early prevention and diagnosis.

导言:抗体介导的免疫反应对慢性阻塞性肺病(COPD)、哮喘和肺功能影响的确切原因仍不清楚。我们描述了抗体介导的免疫反应与慢性阻塞性肺病、哮喘和肺功能之间的关系,最终达到预防或治疗的目的:我们从已发表的全基因组关联研究中获取了汇总数据,包括抗体介导的免疫反应、慢性阻塞性肺病、哮喘、第一秒用力呼气容积(FEV1)、用力呼气容积(FVC)和 FEV1/FVC。双向双样本泯灭随机化(MR)分析用于评估抗体介导的免疫反应、慢性阻塞性肺病、哮喘、第一秒用力呼气容积(FEV1)、用力呼气容积(FVC)和第一秒用力呼气容积(FEV1/FVC)之间的因果关系:结果:共发现 20 种抗体介导的免疫反应对慢性阻塞性肺病、哮喘、FEV1 和 FVC 有显著的因果关系,其中 6 种表现出反向因果关系。重要的是,在抗多瘤病毒 2 IgG 血清阳性和水痘带状疱疹病毒糖蛋白 E 和 I 抗体水平对慢性阻塞性肺病、哮喘、FEV1 和 FVC 风险的因果效应方面,五项 MR 分析的结果几乎相同:本研究采用双样本 MR 设计,调查了抗体介导的免疫反应与慢性阻塞性肺病、哮喘和肺功能等呼吸系统疾病之间的因果关系,为现有知识做出了贡献。主要发现有助于识别这些疾病的高危人群,促进早期预防和诊断。
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引用次数: 0
Asthma-COPD Overlap - A Gateway to Biological Treatment. 哮喘与慢性阻塞性肺病的重叠--通向生物治疗的大门。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM Pub Date : 2024-10-22 DOI: 10.1016/j.arbres.2024.10.006
Alicia Padilla-Galo, Marina Rubio-Moreno, Borja Valencia-Azcona
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Archivos De Bronconeumologia
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