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Archivos De Bronconeumologia最新文献

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Walking Assistance in a Patient with Chronic Obstructive Pulmonary Disease Using a Powered Exoskeleton: A Case Report 使用动力外骨骼辅助慢性阻塞性肺病患者行走：病例报告。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.10.012
Zhongkai Kuai , Fei Zhao , Dan Zeng
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引用次数: 0
CO1
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/S0300-2896(25)00011-0
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引用次数: 0
Quantitative Proteomics Analysis of Serum and Urine With DIA Mass Spectrometry Reveals Biomarkers for Pediatric Obstructive Sleep Apnea 利用 DIA 质谱仪对血清和尿液进行定量蛋白质组学分析，揭示小儿阻塞性睡眠呼吸暂停的生物标记物
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.06.017
Yunxiao Wu , Mansheng Li , Kai Zhang , Jie Ma , David Gozal , Yunping Zhu , Zhifei Xu

Objectives

Identification of suitable biomarkers that facilitate the screening and evaluation of pediatric obstructive sleep apnea (OSA) and its severity was explored.

Methods

Data-independent acquisition quantitative proteomic analysis was employed to identify serum and urine proteins with differential expression patterns between children with OSA and controls. Differentially expressed proteins that gradually increased or decreased with the severity of OSA were retained as potential biomarkers and underwent ELISA validation.

Results

We found that with increasing severity of OSA, there was a gradual upregulation of 34 proteins in the serum and 124 proteins in the urine, along with a respective downregulation of 10 serum proteins and 64 urinary proteins in the initial cohort of 40 children. These proteins primarily participate in immune activation, the complement pathway, oxygen transport, and reactive oxygen metabolism. Notably, cathepsin Z exhibited a positive correlation with the obstructive apnea hypopnea index, whereas sex hormone-binding globulin (SHBG) was negatively correlated. These proteins were then validated by ELISA in an independent cohort (n = 21). Circulating cathepsin Z and SHBG levels displayed acceptable diagnostic performance of OSA with AUC values of 0.863 and 0.738, respectively.

Conclusions

We identified two promising circulating proteins as novel biomarkers for clinical diagnosis and assessment of pediatric OSA severity. Furthermore, the comprehensive proteomic profile in pediatric OSA should aid in exploring the underlying pathophysiological mechanisms associated with this prevalent condition.
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引用次数: 0
A Thoracic Complication of an Abdominal Procedure: Massive Hemothorax Following Percutaneous Transhepatic Portal Vein Angioplasty 腹部手术的胸腔并发症：经皮肝门静脉血管成形术后的大面积血胸。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.10.016
Luis Gorospe , Rut Romera-Sánchez , Gemma María Muñoz-Molina
{"title":"A Thoracic Complication of an Abdominal Procedure: Massive Hemothorax Following Percutaneous Transhepatic Portal Vein Angioplasty","authors":"Luis Gorospe ,&nbsp;Rut Romera-Sánchez ,&nbsp;Gemma María Muñoz-Molina","doi":"10.1016/j.arbres.2024.10.016","DOIUrl":"10.1016/j.arbres.2024.10.016","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 122-123"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Individual and Structural Factors Influencing Participation to Low-Dose Computed Tomography Screening in a Chinese Centralized Lung Cancer Screening Cohort 中国肺癌集中筛查队列中影响参与低剂量计算机断层扫描筛查的个体和结构因素。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.09.009
Shenglin Zhao , Bibo Li , Zhikai Yu , Jia Du , Hong Zhou , Mei He
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引用次数: 0
The New Tobacco Companies Offensive: The Nicotine Pouches 烟草公司的新攻势：尼古丁袋
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.10.017
José Ignacio de Granda-Orive , Carlos A. Jiménez-Ruiz , Mina Gaga
{"title":"The New Tobacco Companies Offensive: The Nicotine Pouches","authors":"José Ignacio de Granda-Orive ,&nbsp;Carlos A. Jiménez-Ruiz ,&nbsp;Mina Gaga","doi":"10.1016/j.arbres.2024.10.017","DOIUrl":"10.1016/j.arbres.2024.10.017","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 65-66"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142674402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Hamartoma With Rare Imaging Features 具有罕见影像学特征的肺脂肪瘤
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.09.015
Xu-ping Chen , Xiao-Dong Yang , Shi-xu He
{"title":"Pulmonary Hamartoma With Rare Imaging Features","authors":"Xu-ping Chen ,&nbsp;Xiao-Dong Yang ,&nbsp;Shi-xu He","doi":"10.1016/j.arbres.2024.09.015","DOIUrl":"10.1016/j.arbres.2024.09.015","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Page 119"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142567401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silicone-induced Lymphadenopathy Mimicking Metastatic Lung Cancer 模拟转移性肺癌的硅酮诱发淋巴腺病
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.10.013
Sara González-Castro , Natalia Cadavid-Fernández , Luis Gorospe Sarasúa
{"title":"Silicone-induced Lymphadenopathy Mimicking Metastatic Lung Cancer","authors":"Sara González-Castro ,&nbsp;Natalia Cadavid-Fernández ,&nbsp;Luis Gorospe Sarasúa","doi":"10.1016/j.arbres.2024.10.013","DOIUrl":"10.1016/j.arbres.2024.10.013","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 120-121"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142638296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of PIKO-6® and COPD-6® Devices in COPD Screening PIKO-6® 和 COPD-6® 设备在慢性阻塞性肺病筛查中的准确性。
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.10.002
Miguel A. Hernández-Mezquita , Idania de los Santos-Ventura , Vanesa Hidalgo-Sierra , Alfonso Pérez-Trullen , Enrique Barrueco-Otero
{"title":"Accuracy of PIKO-6® and COPD-6® Devices in COPD Screening","authors":"Miguel A. Hernández-Mezquita ,&nbsp;Idania de los Santos-Ventura ,&nbsp;Vanesa Hidalgo-Sierra ,&nbsp;Alfonso Pérez-Trullen ,&nbsp;Enrique Barrueco-Otero","doi":"10.1016/j.arbres.2024.10.002","DOIUrl":"10.1016/j.arbres.2024.10.002","url":null,"abstract":"","PeriodicalId":8339,"journal":{"name":"Archivos De Bronconeumologia","volume":"61 2","pages":"Pages 110-112"},"PeriodicalIF":8.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142613682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apnea-Specific Pulse-Rate Response is Associated With Early Subclinical Atherosclerosis in Obstructive Sleep Apnea 呼吸暂停特异性脉率反应与阻塞性睡眠呼吸暂停患者早期亚临床动脉粥样硬化有关
IF 8.7 3区 医学 Q1 RESPIRATORY SYSTEM
Archivos De Bronconeumologia
Pub Date : 2025-02-01 DOI: 10.1016/j.arbres.2024.07.003
Ana Sanchez-Azofra , Jeremy E. Orr , David Sanz-Rubio , Marta Marin-Oto , Sergio Alarcon-Sisamon , Eugenio Vicente , Julio Ancochea , Joan B. Soriano , Pamela DeYoung , Ali Azarbarzin , Atul Malhotra , Jose M. Marin

Introduction

In patients with obstructive sleep apnea (OSA), novel metrics such as hypoxic burden (HB) and sleep apnea-specific pulse-rate response (ΔHR) may better correlate with cardiovascular diseases (CVD) than the apnea–hypopnea index (AHI). This manuscript aims to assess the correlation between ΔHR and HB with subclinical atherosclerosis in patients with OSA, testing the hypothesis that elevated ΔHR and HB are associated with subclinical atherosclerosis development.

Methods

In a prospective study, individuals aged 20–65 years with suspected OSA without known comorbidities were consecutively recruited and defined as OSA (AHI ≥ 5 events/h) or healthy controls. Using bilateral carotid ultrasonography, common carotid intima-media thickness (CIMT) was assessed and the identification of at least one atheromatous plaque defined the presence of subclinical atherosclerosis. ΔHR, and HB were derived from pulse-oximetry.

Results

We studied 296 patients of age 45 ± 10 years old, of whom 28% were women, and with a BMI of 30.3 ± 5.3 kg/m2. Overall, 245 had OSA and 51 were healthy controls. After controlling for confounding variables higher ΔHR but not HB, was associated with higher CIMT (p = 0.006) and higher time spent with oxygen saturation below 90% (T90) was associated with an increase in carotid atheroma plaques (p = 0.032). When stratifying OSA based on HB tertiles, we observed that within tertile 2 of HB, an increase in ΔHR was associated with larger CIMT (p = 0.017).

Conclusion

A higher ΔHR is associated with an increase in CIMT among adult patients with OSA. This study suggests that ΔHR could be a biomarker of risk for CVD in patients with OSA.
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引用次数: 0
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