Archivos De La Sociedad Espanola De Oftalmologia最新文献

英文中文

Redes sociales y oftalmología en España: un nuevo escenario para pacientes y profesionales 西班牙的社交网络和眼科：患者和专业人士的新环境

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.09.002

V. Miralles-Pechuán , J. González Martín-Moro

引用次数: 0

Reversibilidad de la elipsoiditis sifilítica 梅毒性椭球炎的可逆性

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.06.008

F. Garcia Ibor, N. Ruiz del Rio, A. Caro Ortega

引用次数: 0

Evaluación de la apertura palpebral postintervención de reinserción de la aponeurosis elevadora con abordaje anterior y posterior 采用前后方法对升力性肺绞痛重新安置手术后的肺叶开口进行评估

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.07.005

G. Morocho, J.P. Aldecoa, G. Fridrich, S. Vivante, N. Gorjovsky

Background and objective

Levator aponeurosis advancement is a technique used to treat aponeurotic ptosis, which can be performed via anterior (transcutaneous) or posterior (transconjunctival) approach, each with specific advantages. This study aims to evaluate and compare pre- and postoperative eyelid aperture outcomes for both techniques and analyze the rate of over- and undercorrections, contributing to a better understanding of their efficacy and limitations.

Materials and methods

We conducted a retrospective study on 62 eyelids with aponeurotic ptosis and good levator function. A total of 32 anterior and 30 posterior approaches were performed, assessing marginal reflex distance 1 (MRD1), eyelid aperture (EA), and their pre- and postoperative variations, along with the rate of over- and undercorrections relative to ideal values.

Results

MRD1: Preoperative values for the anterior approach were 1.59 ± 1.08 mm, and 0.85 ± 1.00 mm for the posterior approach. Improvements were 2.08 ± 1.59 mm for the anterior approach and 2.13 ± 1.32 mm for the posterior one (p > 0.05).

EA: Improvements were 2.03 ± 2.15 mm for the anterior approach and 2.50 ± 1.66 mm for the posterior one (p > 0.05).

Ideal MRD1 correction (4 mm) was achieved in 31.3% of anterior cases vs 20.0% of posterior cases (p ≈ 0.05).

Ideal EA correction (10 mm) was achieved in 18.8% of anterior cases vs 3.3% of posterior cases (p < 0.05).

Conclusions

Both approaches are effective, but the anterior approach demonstrates higher rates of ideal corrections and fewer undercorrections. The posterior approach was used in lower preoperative DMR1 cases, which may have influenced the results. Selection should be based on the patient's specific characteristics and needs.

背景和目的腱膜提升术是一种用于治疗腱膜性上睑下垂的技术，可以通过前路（经皮）或后路（经结膜）入路进行，每种入路都有其独特的优点。本研究旨在评估和比较这两种技术的术前和术后眼睑光圈结果，并分析矫正过度和矫正不足的比率，从而更好地了解它们的疗效和局限性。材料与方法对62例腱膜性上睑下垂且提上睑肌功能良好的眼睑进行回顾性研究。共进行了32次前路和30次后路手术，评估边缘反射距离1 （MRD1）、眼睑孔径（EA）及其术前和术后变化，以及相对于理想值的过度和不足矫正率。结果smrd1：前路术前值为1.59±1.08 mm，后路术前值为0.85±1.00 mm。前路改善2.08±1.59 mm，后路改善2.13±1.32 mm （p > 0.05）。EA：前路改善2.03±2.15 mm，后路改善2.50±1.66 mm （p > 0.05）。31.3%的前路病例和20.0%的后路病例实现了理想的MRD1矫正（4 mm）（p≈0.05）。18.8%的前路病例和3.3%的后路病例获得理想的EA矫正（10 mm）（p < 0.05）。结论两种入路均有效，但前路理想矫正率较高，矫正不足率较少。术前DMR1较低的病例采用后路入路，这可能影响了结果。选择应根据患者的具体特点和需要。

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引用次数: 0

Análisis de las características biométricas oculares en población mediterránea 地中海人口的眼睛生物特征分析

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.07.010

M. Martínez de la Casa , M. Matilla , J. García Bella , L. Morales , B. Burgos Blasco

Background and Objective

The changes of ocular biometric parameters with age have significant clinical implications for intraocular lens (IOL) power calculation and surgical planning. However, few large-sample studies have analyzed this variability in Mediterranean populations with cataract. The objective of the present study is to analyze the biometric characteristics of a large sample with a complete age representation

Material and Methods

Retrospective observational study including 5,716 eyes. Axial length (AL), corneal radii (R1 and R2), anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white diameter (WTW), and lens thickness (LT) were analyzed. Linear and polynomial regression models were applied to assess their relationship with age. Adjustments for sex were performed using multiple regression.

Results

AL and ACD decreased significantly with age (p < 0.001), while LT increased exponentially from the sixth decade onwards (p < 0.001). No relevant changes were observed in CCT or WTW. Males presented greater AL, ACD, and WTW than females (p < 0.001). Variability increased in older age groups.

Conclusions

This study provides detailed and population-specific reference values for the Mediterranean population with cataract. Identifying morphometric patterns associated with ocular aging enables optimized IOL calculation and risk anticipation in elderly patients.

背景与目的眼生物特征参数随年龄的变化对人工晶状体（IOL）度数的计算和手术计划具有重要的临床意义。然而，很少有大样本研究分析地中海白内障患者的这种变异性。本研究的目的是分析具有完整年龄代表性的大样本的生物特征。材料和方法回顾性观察研究，包括5,716只眼睛。分析眼轴长（AL）、角膜半径（R1和R2）、前房深度（ACD）、角膜中央厚度（CCT）、白到白直径（WTW）和晶状体厚度（LT）。采用线性和多项式回归模型评估其与年龄的关系。使用多元回归对性别进行调整。结果随着年龄的增长，al和ACD显著下降（p < 0.001），而LT从60岁开始呈指数增长（p < 0.001）。CCT和WTW均未见相关变化。男性的AL、ACD和WTW高于女性（p < 0.001）。在年龄较大的人群中，变异性增加。结论本研究为地中海地区白内障患者提供了详细的人群特异性参考价值。识别与眼老化相关的形态学模式可以优化老年患者的人工晶状体计算和风险预测。

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引用次数: 0

Uveítis asociada a inmunoterapia y su respuesta a monoterapia con difluprednato, a propósito de un caso 与免疫治疗有关的Uveitis及其对单药治疗双氟泼尼托的反应，以一个病例为例

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.06.012

C.M. Ortega, A.T. Pérez Bello, B.F. Graizman Kohan, M.D. Eraso Quintero, J. Stuart Pennington, F.M. Preto

Nivolumab and ipilimumab are immune checkpoint inhibitors widely used for the treatment of metastatic melanoma. They can cause various adverse effects in a significant percentage of treated patients, including uveitis. Symptoms include decreased visual acuity, pain, redness, and photophobia, which typically resolve with appropriate anti-inflammatory therapy. The aim of this work is to report a case of uveitis in a patient on ipilimumab and nivolumab for the treatment of metastatic melanoma, as well as the response to therapy with difluprednate.

Nivolumab和ipilimumab是免疫检查点抑制剂，广泛用于治疗转移性黑色素瘤。它们可在很大比例的治疗患者中引起各种不良反应，包括葡萄膜炎。症状包括视力下降、疼痛、发红和畏光，这些症状通常通过适当的抗炎治疗来解决。本研究的目的是报道一例接受伊匹单抗和纳伏单抗治疗转移性黑色素瘤的患者的葡萄膜炎，以及对双氟泼尼酯治疗的反应。

引用次数: 0

Valor de los suplementos de vitamina A en el aumento del grosor macular en un paciente con hipovitaminosis A y nictalopía 维生素A补充对维生素A缺乏症和肾病患者黄斑厚度增加的影响

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.07.004

L. Dominguez García, P. Spang-Valencia, C. Leis-Cofiño, J. Villagrá Lecuona, P. Monreal-Lodeiros, I. Rosa Pérez

Although vitamin A deficiency is a rare cause of nyctalopia, its detection is crucial since vitamin A supplementation can improve vision. This is the case of a 69-year-old woman with progressive night blindness, a past medical history of intestinal surgery, and low vitamin A levels. After vitamin A treatment, her visual acuity improved, along with an increase in macular thickness. Vitamin A is essential for photoreceptor function, and its deficiency is associated with conditions such as xerophthalmia and keratopathy. OCT proved useful in monitoring treatment response. It is important to suspect hypovitaminosis A in patients with risk factors such as bariatric surgery or malabsorption, as its correction can enhance both retinal structure and visual function.

虽然缺乏维生素A是夜盲症的一种罕见原因，但它的检测是至关重要的，因为补充维生素A可以改善视力。这是一名69岁的女性，患有进行性夜盲症，既往有肠道手术史，维生素a水平低。在维生素A治疗后，她的视力有所改善，黄斑厚度也有所增加。维生素A对光感受器功能至关重要，缺乏维生素A与干眼症和角膜病变等疾病有关。OCT被证明在监测治疗反应方面是有用的。在有减肥手术或吸收不良等危险因素的患者中怀疑维生素A缺乏症是很重要的，因为对其进行矫正可以增强视网膜结构和视觉功能。

引用次数: 0

El espectro de anomalías oftalmológicas en MELAS es más amplio de lo esperado MELAS的眼部异常范围比预期的要宽

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.04.011

J. Finsterer

引用次数: 0

Eficacia y seguridad del implante de acetónido de fluocinolona en edema macular y uveítis posterior no infecciosa: seguimiento de 5 años 氟喹诺酮类丙酮类植入物治疗非传染性黄斑水肿和后卵母细胞炎的有效性和安全性：5年随访

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.07.003

N. Ruiz del Rio, F. Garcia Ibor, E. Gracia Rovira, J.M. Vilaplana Mora, L. Sanz Gallen, A.M. Duch Samper

Objective

To evaluate the safety and efficacy profile of the fluocinolone acetonide implant (FAI) in patients with non-infectious posterior segment uveitis over a 60-month follow-up period.

Method

We retrospective conducted a study with a mean follow-up of 47 months (minimum, 18; maximum, 60). The study included 11 eyes (9 patients), with a male-to-female ratio of 1:8. The etiology of uveitis was heterogeneous. Efficacy parameters included visual acuity (VA) and Central macular thickness (CMT), and the ones who needed adjuvant therapy or re-injection. Safety parameters focused on the development of cataracts and intraocular hypertension.

Results

Real-world outcomes were assessed. Both VA recovery and CMT reduction were achieved between 3 to 6 months after FAI implantation and remained stable at the follow-up. All patients but one were pseudophakic prior to implantation. The phakic patient developed early cataract formation, requiring surgery 9 months post-implantation. All cases had previously received intravitreal dexamethasone. Five eyes (45.4%) required topical hypotensive therapy, and none glaucoma surgery. No patient required periodic adjuvant therapy or additional FAI injections, even among those with the longest follow-up periods. Two cases (18.1%) exhibited mild inflammatory activity in the macular area at months 33 and 35 post-implantation. These episodes were successfully resolved with sub-Tenon triamcinolone injections, maintaining clinical stability thereafter.

Conclusions

The FAI, in our series of cases, turned out to be an effective and safe therapy for non-infectious uveitic macular edema, providing sustained and long-lasting effects, in some cases up to 60 months post-implantation. Sub-Tenon triamcinolone proves to be a valuable adjunctive therapy.

目的评价氟西诺酮植入物（FAI）治疗非感染性后段葡萄膜炎患者60个月的安全性和有效性。方法回顾性研究，平均随访47个月（最短18个月，最长60个月）。研究纳入11只眼（9例），男女比例为1:8。葡萄膜炎的病因不同。疗效指标包括视力（VA）、中央黄斑厚度（CMT）及是否需要辅助治疗或再注射。安全性参数集中在白内障和眼内高压的发展。结果评估了真实世界的结果。在植入FAI后3 - 6个月，VA恢复和CMT减少均可实现，并在随访中保持稳定。除1例患者外，所有患者在植入前均为假性晶状体。晶状体患者出现早期白内障形成，在晶状体植入术9个月后需要手术。所有病例均曾接受玻璃体内地塞米松治疗。5只眼（45.4%）需要局部降压治疗，没有青光眼手术。没有患者需要定期辅助治疗或额外的FAI注射，即使是那些随访时间最长的患者。2例（18.1%）在植入后33个月和35个月黄斑区出现轻度炎症活动。这些发作成功地解决了亚tenon曲安奈德注射，此后保持临床稳定。结论：在我们的一系列病例中，FAI被证明是一种有效和安全的治疗非感染性葡萄膜黄斑水肿的方法，具有持续和持久的效果，在某些情况下可达植入后60个月。亚tenon曲安奈德被证明是一种有价值的辅助治疗。

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引用次数: 0

Retinopatía asociada a síndrome de MELAS. A propósito de un caso 与MELAS综合征相关的视网膜病变。关于一个案例

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.06.020

A.B. González Escobar

引用次数: 0

Hamartoma congénito simple del epitelio pigmentario de la retina bilateral 双侧视网膜色素上皮的简单先天性畸形

Q3 Medicine

Archivos De La Sociedad Espanola De Oftalmologia

Pub Date : 2025-12-01 DOI: 10.1016/j.oftal.2025.06.017

S. Mejía-Freire , G. De La Mata

Congenital simple hamartoma of the retinal pigment epithelium is a rare, benign retinal lesion, rarely seen bilaterally. This case shows a 46-year-old man initially misdiagnosed with macular dystrophy, whose vision progressively declined over several years due to concomitant cataracts. Multimodal imaging, including OCT, was key in differentiating from more serious conditions such as choroidal melanoma. With no growth or secondary complications, the lesion remains under regular monitoring. This case underscores the importance of imaging in distinguishing CSHRPE from other chorioretinal disorders.

先天性单纯性视网膜色素上皮错构瘤是一种罕见的良性视网膜病变，罕见于双侧。本病例显示一名46岁男子最初被误诊为黄斑营养不良，由于并发白内障，其视力在几年内逐渐下降。包括OCT在内的多模态成像是区分脉络膜黑色素瘤等更严重疾病的关键。由于没有生长或继发性并发症，病变仍需定期监测。本病例强调了影像学在鉴别CSHRPE与其他绒毛膜视网膜疾病中的重要性。

引用次数: 0

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