Pub Date : 2025-01-01DOI: 10.1016/j.oftal.2024.08.007
L.M. Vindel Valle , M.A. López Alfaro
Case report
Case report of a 51 year old patient diagnosed with atypical Cogan's syndrome. The patient exhibited interstitial keratitis, anterior uveitis, and long-standing profound deafness. The treatment was based on topical and systemic steroids, resulting in a satisfactory evolution and currently in clinical remission.
Discussion
Cogan's syndrome is a chronic inflammatory disease that has existed for over 60 years. Because its diagnosis is purely clinical, not many cases have been reported worldwide. Therefore, it is important to be aware of this condition to make a quick diagnosis and provide multidisciplinary treatment, thus preventing irreversible complications.
{"title":"Primer caso reportado de síndrome de Cogan atípico en Centroamérica","authors":"L.M. Vindel Valle , M.A. López Alfaro","doi":"10.1016/j.oftal.2024.08.007","DOIUrl":"10.1016/j.oftal.2024.08.007","url":null,"abstract":"<div><h3>Case report</h3><div>Case report of a 51 year old patient diagnosed with atypical Cogan's syndrome. The patient exhibited interstitial keratitis, anterior uveitis, and long-standing profound deafness. The treatment was based on topical and systemic steroids, resulting in a satisfactory evolution and currently in clinical remission.</div></div><div><h3>Discussion</h3><div>Cogan's syndrome is a chronic inflammatory disease that has existed for over 60 years. Because its diagnosis is purely clinical, not many cases have been reported worldwide. Therefore, it is important to be aware of this condition to make a quick diagnosis and provide multidisciplinary treatment, thus preventing irreversible complications.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 1","pages":"Pages 42-45"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-01DOI: 10.1016/j.oftal.2024.07.002
R. Montejano-Milner , M. Sánchez-Orgaz , R. Romero-Martín , J.V. Dabad-Moreno , I. Mogollón-Giralt , M.A. Roca-Cabau , A. de la Hoz Polo , Á. Arbizu-Duralde
Purpose
To report results and complications from a series of 17 proximal lacrimal pathway obstructions (PLPO) treated with conjunctivo-rhinostomy (CR) and Métaireau tube implantation.
Methods
We conducted a retrospective descriptive study including 16 patients (17 PLPO) treated with CR from April 2010 through June 2017. Surgical procedures were performed under general anesthesia. Métaireau tube implantation draining into the middle meatus was performed through a trans-caruncular osteotomy using a 14G Abbocath catheter under endoscopic control.
Results
A total of 12 women (75%) and 4 men (25%) were included. The median age was 57 years (range, 32-78). The indication for surgery was constant epiphora (Munk 4) due to obstruction < 8 mm from the punctum. The follow-up time was 28 months (range, 2-85). Epiphora improved 1 month after the intervention (Munk 0.35 ± 1) and at the end of follow-up (Munk 1.50 ± 1.10) vs baseline values (Munk 4). The most comon postoperative symptoms were hyperemia (35%), discharge (24%), and tearing (24%). The signs found were conjunctival folds and papillomas at the proximal end of the tube (35% and 24%, respectively) and tube malapposition (18%). One patient developed restrictive strabismus. A total of 41% of the cases required, at least, 1 surgery to reposition or remove the tube.
Conclusions
CR with Métaireau tube implantation is a therapeutic alternative for PLPO. Despite the good anatomic results, patients should be warned about the potential complications, which are common and may require reinterventions.
{"title":"Conjuntivo-rinostomía con implante de tubo de Métaireau: resultados y complicaciones","authors":"R. Montejano-Milner , M. Sánchez-Orgaz , R. Romero-Martín , J.V. Dabad-Moreno , I. Mogollón-Giralt , M.A. Roca-Cabau , A. de la Hoz Polo , Á. Arbizu-Duralde","doi":"10.1016/j.oftal.2024.07.002","DOIUrl":"10.1016/j.oftal.2024.07.002","url":null,"abstract":"<div><h3>Purpose</h3><div>To report results and complications from a series of 17 proximal lacrimal pathway obstructions (PLPO) treated with conjunctivo-rhinostomy (CR) and Métaireau tube implantation.</div></div><div><h3>Methods</h3><div>We conducted a retrospective descriptive study including 16 patients (17 PLPO) treated with CR from April 2010 through June 2017. Surgical procedures were performed under general anesthesia. Métaireau tube implantation draining into the middle meatus was performed through a trans-caruncular osteotomy using a 14G Abbocath catheter under endoscopic control.</div></div><div><h3>Results</h3><div>A total of 12 women (75%) and 4 men (25%) were included. The median age was 57 years (range, 32-78). The indication for surgery was constant epiphora (Munk 4) due to obstruction < 8<!--> <!-->mm from the punctum. The follow-up time was 28 months (range, 2-85). Epiphora improved 1 month after the intervention (Munk 0.35<!--> <!-->±<!--> <!-->1) and at the end of follow-up (Munk 1.50<!--> <!-->±<!--> <!-->1.10) vs baseline values (Munk 4). The most comon postoperative symptoms were hyperemia (35%), discharge (24%), and tearing (24%). The signs found were conjunctival folds and papillomas at the proximal end of the tube (35% and 24%, respectively) and tube malapposition (18%). One patient developed restrictive strabismus. A total of 41% of the cases required, at least, 1 surgery to reposition or remove the tube.</div></div><div><h3>Conclusions</h3><div>CR with Métaireau tube implantation is a therapeutic alternative for PLPO. Despite the good anatomic results, patients should be warned about the potential complications, which are common and may require reinterventions.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"100 1","pages":"Pages 8-15"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143155718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.07.005
L. Picasso Simón , M. Castro-Rebollo , B. Sastre Borregón , J. González-Martín-Moro
A 56-year-old woman with a history of severe endometriosis, followed at our center for 16 years due to multiple episodes of horizontal binocular diplopia, was diagnosed with recurrent paresis of the VI cranial nerve of her right eye. Magnetic resonance imaging revealed localized pachymeningitis in her right cavernous sinus. Initial episodes were treated with botulinum toxin. Subsequently, she declined treatment during inter-crisis periods because she remains asymptomatic. Idiopathic hypertrophic pachymeningitis is a rare condition of unknown cause, characterized by chronic inflammation of the meninges resulting in localized or diffuse dural thickening. Clinical manifestations vary widely, from generalized processes with complex neurological symptoms to localized processes with monosymptomatic expression, as presented in this case.
{"title":"Parálisis recurrente del VI nervio craneal secundaria a paquimeningitis idiopática del seno cavernoso: comunicación de un caso","authors":"L. Picasso Simón , M. Castro-Rebollo , B. Sastre Borregón , J. González-Martín-Moro","doi":"10.1016/j.oftal.2024.07.005","DOIUrl":"10.1016/j.oftal.2024.07.005","url":null,"abstract":"<div><div>A 56-year-old woman with a history of severe endometriosis, followed at our center for 16<!--> <!-->years due to multiple episodes of horizontal binocular diplopia, was diagnosed with recurrent paresis of the VI cranial nerve of her right eye. Magnetic resonance imaging revealed localized pachymeningitis in her right cavernous sinus. Initial episodes were treated with botulinum toxin. Subsequently, she declined treatment during inter-crisis periods because she remains asymptomatic. Idiopathic hypertrophic pachymeningitis is a rare condition of unknown cause, characterized by chronic inflammation of the meninges resulting in localized or diffuse dural thickening. Clinical manifestations vary widely, from generalized processes with complex neurological symptoms to localized processes with monosymptomatic expression, as presented in this case.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 558-561"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.08.003
J. González Martín-Moro
{"title":"PHOMS: estructuras ovoides que habitualmente no tienen forma de huevo","authors":"J. González Martín-Moro","doi":"10.1016/j.oftal.2024.08.003","DOIUrl":"10.1016/j.oftal.2024.08.003","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 574-575"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.08.005
N.C. Pereyra , L.G. Otonelli , M.A. Arriaga , L.L. Iacono , M.L. Braccia Gancedo , L. Sarotto
Background
Bone metastases due to prostate adenocarcinoma usually present osteoblastic characteristics on the imaging modalities.
Method
Case report.
Results
A 77-year-old patient diagnosed with prostate adenocarcinoma with osteoblastic metastases in the dorsal spine and ribs, empirically treated with decongestants for symptoms associated with nasal polyposis, presented with binocular diplopia and ptosis of the right eyelid. Painful ophthalmoplegia and ipsilateral frozen orbit were observed. The CT confirmed the presence of a soft tissue density neoformation infiltrating the paranasal sinuses spreading towards to the base of the skull and extraocular muscles. Biopsy by endoscopic sinus surgery triggered the diagnosis of metastasis.
Conclusions
Regardless of the characteristics seen on the imaging modalities, onset in other organs and systems in patients with a history of prostate adenocarcinoma should prompt the histopathological study of the lesions.
{"title":"Metástasis no osteoblástica rinosinusal y orbitaria por adenocarcinoma de próstata","authors":"N.C. Pereyra , L.G. Otonelli , M.A. Arriaga , L.L. Iacono , M.L. Braccia Gancedo , L. Sarotto","doi":"10.1016/j.oftal.2024.08.005","DOIUrl":"10.1016/j.oftal.2024.08.005","url":null,"abstract":"<div><h3>Background</h3><div>Bone metastases due to prostate adenocarcinoma usually present osteoblastic characteristics on the imaging modalities.</div></div><div><h3>Method</h3><div>Case report.</div></div><div><h3>Results</h3><div>A 77-year-old patient diagnosed with prostate adenocarcinoma with osteoblastic metastases in the dorsal spine and ribs, empirically treated with decongestants for symptoms associated with nasal polyposis, presented with binocular diplopia and ptosis of the right eyelid. Painful ophthalmoplegia and ipsilateral frozen orbit were observed. The CT confirmed the presence of a soft tissue density neoformation infiltrating the paranasal sinuses spreading towards to the base of the skull and extraocular muscles. Biopsy by endoscopic sinus surgery triggered the diagnosis of metastasis.</div></div><div><h3>Conclusions</h3><div>Regardless of the characteristics seen on the imaging modalities, onset in other organs and systems in patients with a history of prostate adenocarcinoma should prompt the histopathological study of the lesions.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 570-573"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.06.009
E. Gracia-Rovira, V.T. Pérez-Torregrosa, A.M. Duch-Samper
{"title":"Tomografía de coherencia óptica de segmento anterior para el diagnóstico diferencial de quiste de iris","authors":"E. Gracia-Rovira, V.T. Pérez-Torregrosa, A.M. Duch-Samper","doi":"10.1016/j.oftal.2024.06.009","DOIUrl":"10.1016/j.oftal.2024.06.009","url":null,"abstract":"","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Page 577"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141843306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.06.008
P. Luque-Linero , A. Espejo-González , N. Navarrete-Navarrete
Objective
To describe the characteristics of patients with uveitis and ocular complications in a tertiary hospital. As well as to determine the risk factors for the development of an ocular complication.
Methods
Retrospective study of patients with uveitis evaluated in a Uveitis Unit of the Virgen de las Nieves Hospital from January 2018 to October 2022. A descriptive and analytical study was carried out using logistic regression to know the predictive factors of a poor ocular prognosis.
Results
A total of 127 patients were studied, of which 63% were women and 83.5% were Caucasian. The median age was 51 years IQR (15-88) years. Following the SUN classification, uveitis was predominantly bilateral (55.1%) and anterior (52%), had a recurrent evolution in 51,2% and only 12,6% were granulomatous. Of the total uveitis, 74,2% of the sample turned out to have an immune-mediated profile, although a final diagnosis was only reached in 46,1% of the patients. A total of 17,3% patients suffer from loss of vision. Visual complications in decreasing order were: posterior synechiae (15,6%), cystic macular edema (14.8%), cataracts (13,1%), glaucoma (8,2%), epiretinal membranes (4,9%) and neovascular membranes (1,7%) and retinal detachment (4%). In the bivariate analysis, ethnicity other than Caucasian was significant, p = 0,024, and a number of outbreaks greater than 2, p = 0,045. The rest of the variables analyzed were not significant. In the multivariate analysis, they were significant outbreaks OR: 1,2 CI (1,051- 1,426) and ethnicity OR: 0,11 CI (0,014- 0,938).
Conclusions
The number of outbreaks and non-Caucasian race were related to a greater probability of presenting an ocular complication. An earlier and more specific diagnosis of the etiology, especially in these patients, would allow earlier treatment and improve their prognosis.
{"title":"Prevalencia y factores de riesgo para padecer una uveítis inmunomediada con mal pronóstico ocular: experiencia en un hospital de tercer nivel","authors":"P. Luque-Linero , A. Espejo-González , N. Navarrete-Navarrete","doi":"10.1016/j.oftal.2024.06.008","DOIUrl":"10.1016/j.oftal.2024.06.008","url":null,"abstract":"<div><h3>Objective</h3><div>To describe the characteristics of patients with uveitis and ocular complications in a tertiary hospital. As well as to determine the risk factors for the development of an ocular complication.</div></div><div><h3>Methods</h3><div>Retrospective study of patients with uveitis evaluated in a Uveitis Unit of the Virgen de las Nieves Hospital from January 2018 to October 2022. A descriptive and analytical study was carried out using logistic regression to know the predictive factors of a poor ocular prognosis.</div></div><div><h3>Results</h3><div>A total of 127 patients were studied, of which 63% were women and 83.5% were Caucasian. The median age was 51 years IQR (15-88) years. Following the SUN classification, uveitis was predominantly bilateral (55.1%) and anterior (52%), had a recurrent evolution in 51,2% and only 12,6% were granulomatous. Of the total uveitis, 74,2% of the sample turned out to have an immune-mediated profile, although a final diagnosis was only reached in 46,1% of the patients. A total of 17,3% patients suffer from loss of vision. Visual complications in decreasing order were: posterior synechiae (15,6%), cystic macular edema (14.8%), cataracts (13,1%), glaucoma (8,2%), epiretinal membranes (4,9%) and neovascular membranes (1,7%) and retinal detachment (4%). In the bivariate analysis, ethnicity other than Caucasian was significant, p<!--> <!-->=<!--> <!-->0,024, and a number of outbreaks greater than 2, p<!--> <!-->=<!--> <!-->0,045. The rest of the variables analyzed were not significant. In the multivariate analysis, they were significant outbreaks OR: 1,2 CI (1,051- 1,426) and ethnicity OR: 0,11 CI (0,014- 0,938).</div></div><div><h3>Conclusions</h3><div>The number of outbreaks and non-Caucasian race were related to a greater probability of presenting an ocular complication. An earlier and more specific diagnosis of the etiology, especially in these patients, would allow earlier treatment and improve their prognosis.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 540-547"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141847823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.06.007
D. Rego-Lorca, J. Català-Mora, A. López-de-Eguileta, J. Díaz-Cascajosa
Purpose
To provide data on the most frequent causes, main characteristics, management, and outcomes of pediatric choroidal neovascularization (CNV) in a major tertiary referral hospital for children, together with a review of the current literature.
Methods
Case series including children diagnosed with CNV between 2008 and 2023. Age, sex, date of diagnosis, CNV etiology, CNV localization, treatment with anti-vascular endothelial growth factor (VEGF), and ophthalmological examination data at diagnosis and after one year of follow-up were recorded.
Results
42 eyes (31 patients) were included. Best's disease (35.5%) was the most frequent etiology, followed by intraocular inflammation (25.8%). Most neovascular membranes (78.6%) were located within 1 disc diameter of the fovea centre. 78.6% of eyes received anti-VEGF treatment. Mean visual acuity (VA) significantly improved from logMAR 0.57 to 0.31 after one year of follow-up.
Conclusion
CNV in children is a serious condition with severe ophthalmological consequences. Although certain patients may spontaneously improve or maintain good VA without treatment, in many others anti-VEGF treatment may lead to significant visual improvement. VA impairment, signs of exudative CNV on OCT images and the location of CNV seem to be the most important features in the decision to treat or not to treat these patients.
{"title":"Neovascularización coroidea en niños: etiología, características clínicas y resultados del tratamiento","authors":"D. Rego-Lorca, J. Català-Mora, A. López-de-Eguileta, J. Díaz-Cascajosa","doi":"10.1016/j.oftal.2024.06.007","DOIUrl":"10.1016/j.oftal.2024.06.007","url":null,"abstract":"<div><h3>Purpose</h3><div>To provide data on the most frequent causes, main characteristics, management, and outcomes of pediatric choroidal neovascularization (CNV) in a major tertiary referral hospital for children, together with a review of the current literature.</div></div><div><h3>Methods</h3><div>Case series including children diagnosed with CNV between 2008 and 2023. Age, sex, date of diagnosis, CNV etiology, CNV localization, treatment with anti-vascular endothelial growth factor (VEGF), and ophthalmological examination data at diagnosis and after one year of follow-up were recorded.</div></div><div><h3>Results</h3><div>42 eyes (31 patients) were included. Best's disease (35.5%) was the most frequent etiology, followed by intraocular inflammation (25.8%). Most neovascular membranes (78.6%) were located within 1 disc diameter of the fovea centre. 78.6% of eyes received anti-VEGF treatment. Mean visual acuity (VA) significantly improved from logMAR 0.57 to 0.31 after one year of follow-up.</div></div><div><h3>Conclusion</h3><div>CNV in children is a serious condition with severe ophthalmological consequences. Although certain patients may spontaneously improve or maintain good VA without treatment, in many others anti-VEGF treatment may lead to significant visual improvement. VA impairment, signs of exudative CNV on OCT images and the location of CNV seem to be the most important features in the decision to treat or not to treat these patients.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 534-539"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141854034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.07.009
M. Zamorano , B. Puerto , J. Carceller , J.J. González-López , M.S. Figueroa , F.J. Muñoz-Negrete
Type 1 neovascularization with aneurysmal dilations (N1a), is a retinal disorder characterized by choroidal vascular abnormalities. Clinically, it is characterized by an exudative maculopathy with multiple recurrent serosanguineous pigment epithelial detachments. This disease is more common in women aged 55-65 years. However, we present an exceptional case of N1a in a 26-year-old woman, who responded favorably to aflibercept. As far as we know, this is the first case ever reported of a young woman under 30 with N1a. The patient has responded very favourably to anti-VEGF therapy with three intravitreal injections of aflibercept. Moreover, we provide an update on anti-VEGF therapeutic options for N1a.
{"title":"Presentación atípica de neovascularización tipo 1 con dilataciones aneurismáticas en una mujer joven","authors":"M. Zamorano , B. Puerto , J. Carceller , J.J. González-López , M.S. Figueroa , F.J. Muñoz-Negrete","doi":"10.1016/j.oftal.2024.07.009","DOIUrl":"10.1016/j.oftal.2024.07.009","url":null,"abstract":"<div><div>Type 1 neovascularization with aneurysmal dilations (N1a), is a retinal disorder characterized by choroidal vascular abnormalities. Clinically, it is characterized by an exudative maculopathy with multiple recurrent serosanguineous pigment epithelial detachments. This disease is more common in women aged 55-65 years. However, we present an exceptional case of N1a in a 26-year-old woman, who responded favorably to aflibercept. As far as we know, this is the first case ever reported of a young woman under 30 with N1a. The patient has responded very favourably to anti-VEGF therapy with three intravitreal injections of aflibercept. Moreover, we provide an update on anti-VEGF therapeutic options for N1a.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 562-565"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-01DOI: 10.1016/j.oftal.2024.07.010
C. Klein-Burgos , L. Sanjuán-Riera , M. Larrañaga-Cores , E. Fernández-Gutiérrez , A. Boto-de los Bueis
A 57-year-old male presented to our clinic with acute corneal hydrops. He had been diagnosed with pellucid marginal degeneration (PMD) three years before. Since conservative treatment and intracameral air injections failed to resolve the corneal edema, we decided to perform a thermokeratoplasty (TKP) plus an amniotic membrane transplantation (AMT). Two weeks after the procedure the patient did not have any pain, corneal edema resolved, and best corrected visual acuity (BCVA) improved from counting fingers to 1 logMAR. During the two-year follow-up the patient has remained asymptomatic, at the 2-year follow-up, BCVA is 0.2 logMAR, corneal steepness has reduced in inferior perifery from 71.3 diopters (D) down to 56.7 D and just a mild leukoma remains at the original hydrops presentation site.
TKP combined with AMT should be considered as a treatment option in acute corneal hydrops, especially in patients with peripheral location as PMD, uncompliant patients, and refractory cases.
{"title":"Termoqueratoplastia y trasplante de membrana amniótica como tratamiento del hidrops corneal refractario en un paciente con degeneración marginal pelúcida","authors":"C. Klein-Burgos , L. Sanjuán-Riera , M. Larrañaga-Cores , E. Fernández-Gutiérrez , A. Boto-de los Bueis","doi":"10.1016/j.oftal.2024.07.010","DOIUrl":"10.1016/j.oftal.2024.07.010","url":null,"abstract":"<div><div>A 57-year-old male presented to our clinic with acute corneal hydrops. He had been diagnosed with pellucid marginal degeneration (PMD) three years before. Since conservative treatment and intracameral air injections failed to resolve the corneal edema, we decided to perform a thermokeratoplasty (TKP) plus an amniotic membrane transplantation (AMT). Two weeks after the procedure the patient did not have any pain, corneal edema resolved, and best corrected visual acuity (BCVA) improved from counting fingers to 1<!--> <!-->logMAR. During the two-year follow-up the patient has remained asymptomatic, at the 2-year follow-up, BCVA is 0.2<!--> <!-->logMAR, corneal steepness has reduced in inferior perifery from 71.3 diopters (D) down to 56.7<!--> <!-->D and just a mild leukoma remains at the original hydrops presentation site.</div><div>TKP combined with AMT should be considered as a treatment option in acute corneal hydrops, especially in patients with peripheral location as PMD, uncompliant patients, and refractory cases.</div></div>","PeriodicalId":8348,"journal":{"name":"Archivos De La Sociedad Espanola De Oftalmologia","volume":"99 12","pages":"Pages 566-569"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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