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Quiste de inclusión epitelial secundario a cirugía de glaucoma: serie de casos 继发于青光眼手术的上皮包涵囊肿:病例系列
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.05.005
B. Benito-Pascual , O. Rodríguez-Quet , C. Méndez-Hernández , L. Álvarez-Cascos-López , L. Gil-Amado , J. García-Feijoo

Epithelial inclusion cysts (EIC) are a rare ocular disease and its physiopathology is not well-known. They consist on growths of ocular surface epithelial cells inside the anterior segment of the eye in the form of a cyst. To date several cases have been published in the literature, none of them related to glaucoma surgery. We describe two cases of EIC after glaucoma devices implantation. An 86 year-old male patient with primary open angle glaucoma develop an EIC in right eye three years after removal of PRESERFLO™MicroShunt (Santen, Osaka, Japan) and a 9 year-old female patient with glaucoma secondary to uveitis for juvenile idiopathic arthritis develops an EIC under the tube of an Ahmed valve implant during postoperative period. EIC develop after ocular penetrating wounds and an inflammatory stimulus. They are benign proliferations, follow-up is necessary to detect space complications early, so less mutilating surgery is needed for removal.

上皮包涵囊肿(EIC)是一种罕见的眼部疾病,其生理病理尚不清楚。这种疾病是眼表上皮细胞在眼球前段内以囊肿的形式生长。迄今为止,已有多篇文献发表了此类病例,但都与青光眼手术无关。我们描述了两例青光眼设备植入术后的 EIC 病例。一位 86 岁的原发性开角型青光眼男性患者在取出 PRESERFLO™MicroShunt(日本大阪山腾公司)三年后,右眼出现了 EIC;一位 9 岁的幼年特发性关节炎葡萄膜炎继发性青光眼女性患者在术后期间,在 Ahmed 瓣膜植入物的导管下出现了 EIC。EIC 是在眼球穿透伤和炎症刺激后出现的。它们属于良性增生,有必要进行随访,以便及早发现空间并发症,从而减少切除手术的创伤。
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引用次数: 0
Tributo a John Tyndall en el 130 aniversario de su muerte 在约翰-廷德尔逝世 130 周年之际向他致敬
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.02.008
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引用次数: 0
Complejidad diagnóstica y terapéutica del síndrome de Susac 苏萨克综合征诊断和治疗的复杂性
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.03.011

A 40-year-old man who attended the emergency department with a scotoma in right eye. He mentioned hearing difficulties and headache for months and he had sensory and motor deficits in the previous days. In the ophthalmic examination, the right eye had areas of arterial occlusion. MRI revealed hyperintense lesions. The patient was diagnosed with Susac syndrome.

He was treated with systemic steroids, however, it was not enough to control the condition. Rituximab and intravenous immunoglobulins were added, which allowed the improvement of neurological symptoms, but the alteration of the visual field and the hearing defect did not recover.

Early diagnosis of this pathology is essential, since delaying treatment can cause irreversible consequences. Sometimes it is difficult given the wide variety of symptoms and the course of the disease. Ocular manifestations may raise suspicion when the general symptoms are nonspecific.

一名 40 岁的男子因右眼出现视力模糊而到急诊科就诊。他提到听力障碍和头痛已持续数月,前几天还出现了感觉和运动障碍。在眼科检查中,右眼有动脉闭塞的区域。磁共振成像显示有高强度病变。患者被诊断为苏萨克综合征。他接受了全身类固醇治疗,但仍不足以控制病情。他接受了全身类固醇治疗,但仍不足以控制病情,于是又接受了利妥昔单抗和静脉注射免疫球蛋白治疗,结果神经症状有所改善,但视野改变和听力缺陷并未恢复。由于症状和病程多种多样,有时很难做出诊断。当全身症状无特异性时,眼部表现可能会引起怀疑。
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引用次数: 0
Aceite de silicona emulsionado en cámara anterior 前房乳化醋酸矽胶
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.04.005
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引用次数: 0
Retinopatía por radiación vs. síndrome isquémico ocular: ¿cómo llegar al diagnóstico? 辐射视网膜病变与眼缺血综合征:如何确诊?
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.05.003
A. Aramburu-González , J. Zarrabeitia Carrandi , C.B. Robles Elejalde , A. Quilez Larragan

We present a case of diagnostic interest; we present the differential diagnosis and the complementary tests necessary to reach it, in addition to highlighting the importance of a correct collection of background and clinical history. A 54-year-old woman with a history of carcinoma of the floor of the mouth treated with radiotherapy and chemotherapy develops ischemic retinopathy. It was necessary to perform a systemic study and differential diagnosis with entities such as ocular ischemic syndrome and radiation retinopathy, due to the similarity in the clinical findings found.

Radiation retinopathy should be ruled out in any patient with visual impairment and a history of radiotherapy treatment. A broad differential diagnosis and systemic study are required to rule out entities such as ocular ischemic syndrome and diabetic retinopathy, in addition to early treatment to avoid possible complications.

我们将介绍一例具有诊断意义的病例;除了强调正确收集背景资料和临床病史的重要性外,我们还将介绍鉴别诊断和达到诊断结果所需的辅助检查。一名 54 岁的妇女曾患口腔底癌,接受过放疗和化疗,后来出现缺血性视网膜病变。由于发现的临床表现相似,有必要进行系统研究,并与眼部缺血综合征和放射性视网膜病变等实体进行鉴别诊断。除了及早治疗以避免可能出现的并发症外,还需要进行广泛的鉴别诊断和系统研究,以排除眼缺血综合征和糖尿病视网膜病变等疾病。
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引用次数: 0
Validación Rasch del Keratoconus End-Points Assessment Questionnaire en población española con queratocono 在西班牙角膜炎患者中对角膜炎终点评估问卷进行 Rasch 验证。
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.04.007

Objective

To carry out a methodologically complete validation of the Spanish version of the Keratoconus End-Points Assessment Questionnaire (KEPAQ) in a Spanish population with keratoconus.

Method

Analytical, prospective study, including patients with keratoconus without previous surgical history, in which a measurement of quality of life was performed using the KEPAQ questionnaire, a complete exploration of the anterior pole and a corneal elevation topography with the Galilei™ G6 topographer. The evaluation of the psychometric characteristics of the scale in the studied population was carried out using Rasch modeling.

Results

A total of 140 patients with keratoconus were included, with a median age of 26.0 years, the majority (57.6%) being men. For the KEPAQ-E subscale, the median score was 69.3, with a reliability of 0.85 and an eigenvalue of the first contrast of 2.34. For the KEPAQ-F, the median score was 56.4, with a reliability of 0.88 and an eigenvalue of 2.00. All infit and outfit parameters were within normal limits for both subscales. A significant evaluation was found between the evaluations of both subscales (rho = 0.696; p < 0.001). The evaluations of the subscales and various clinical and tomographic characteristics showed a significant classification between them (p value between 0.048 y 0.001).

Conclusion

The KEPAQ is a psychometrically robust and valid scale to evaluate quality of life in the Spanish population with keratoconus. This questionnaire can be easily used for both clinical and research aims.

方法分析性前瞻性研究,纳入无手术史的角膜炎患者,使用 KEPAQ 问卷、前极点全面检查和 Galilei™ G6 角膜地形图仪进行角膜抬高地形图检查,测量患者的生活质量。结果共纳入了 140 名角膜炎患者,中位年龄为 26.0 岁,大多数(57.6%)为男性。KEPAQ-E 分量表的中位数为 69.3 分,信度为 0.85,第一次对比的特征值为 2.34。KEPAQ-F 的中位数为 56.4 分,信度为 0.88,特征值为 2.00。两个分量表中的所有信息和装备参数都在正常范围内。两个分量表的评价之间存在明显差异(rho = 0.696; p < 0.001)。各分量表的评估结果与各种临床特征和断层扫描特征之间存在显著的分级关系(p 值介于 0.048 和 0.001 之间)。该问卷可轻松用于临床和研究目的。
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引用次数: 0
Traducción, adaptación y validación transcultural de la escala CDQ-24 en pacientes con blefaroespasmo primario en tratamiento con toxina botulínica, prueba piloto 在接受肉毒杆菌毒素治疗的原发性眼睑痉挛患者中进行 CDQ-24 量表的翻译、改编和跨文化验证试验。
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.04.001
A.J. Mejía-Vergara , L. Méndez Cardona , D.A. Flórez Rocha , N. Rozo , J.V. Rincón López

Background

Benign essential blepharospasm is the most common adult-onset focal facial dystonia and its treatment of choice is periodic application of botulinum toxin (BtA). It has a higher incidence in middle and late adulthood, especially in women between 40 and 60 years of age.

Objective

To carry out the translation and cross-cultural adaptation of the CDQ24 questionnaire in its Spanish version in patients diagnosed with benign essential blepharospasm who have been treated with BtA in an ophthalmologic center in Bogotá - Colombia.

Materials and methods

Pilot test of validation study and adaptation of a scale assembled in a prospective cohort of the CDQ24 instrument to Spanish in adult patients with primary blepharospasm treated with botulinum toxin in Bogota, Colombia.

Results

We obtained a sample of 26 patients to whom the instrument was applied after translation and retranslation of the original document, composed of 19 (73%) women with a median age of 64.5 years; the average time to answer the survey was 4.93 minutes. The internal consistency of the scale evaluated by Cronbach's Alpha had a total score of 0.78. Criterion validity between the CDQ24 scale and the WHOQOL-BREF quality of life scale was determined by determining correlation between the Emotional Well-Being and Phsychological domains of both scales.

Conclusions

The translation and cross-cultural adaptation of the CDQ-24 scale into Spanish allowed the applicability of the instrument to the Spanish-speaking population during the pilot test, which allows us to continue the relevant studies in the study population.

背景良性本质性睑痉挛是成人最常见的局灶性面部肌张力障碍,其治疗方法是定期应用肉毒杆菌毒素(BtA)。目的在哥伦比亚波哥大的一家眼科中心,对已接受 BtA 治疗的良性眼睑痉挛患者进行 CDQ24 问卷西班牙文版的翻译和跨文化改编。材料与方法在哥伦比亚波哥大对接受肉毒杆菌毒素治疗的原发性眼睑痉挛成年患者进行了CDQ24问卷西班牙文前瞻性队列的验证研究和量表改编试点测试。结果我们获得了26名患者样本,在对原始文件进行翻译和重译后,对其进行了问卷调查,其中包括19名(73%)女性患者,中位年龄为64.5岁;回答问卷的平均时间为4.93分钟。量表的内部一致性由 Cronbach's Alpha 评估,总分为 0.78。CDQ24 量表与 WHOQOL-BREF 生活质量量表之间的标准效度是通过确定两个量表的情感-幸福和心理领域之间的相关性来确定的。结论将 CDQ-24 量表翻译成西班牙语并进行跨文化改编,使该工具在试点测试期间适用于西班牙语人群,这使我们能够在研究人群中继续开展相关研究。
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引用次数: 0
Queratoconjuntivitis mucosinequiante secundaria a liquen plano ocular: a propósito de un caso 继发于眼部扁平苔藓的黏液性结膜炎角结膜炎:一份病例报告
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.03.001

The aim of this article is to report clinical features and therapeutic approach of cicatrizing keratoconjunctivitis secondary to ocular lichen planus based on a case report. The patient is a 77-year-old female with a history of ocular discomfort and recurrent keratoconjunctivitis that did not improve with conservative treatment, as well as a history of oral and nasal aphthous ulcers. After a complete ophthalmologic, dermatologic and anatomopathological study, the diagnosis of ocular lichen planus was established and immunosuppressive treatment was initiated.

Most cases of ocular lichen planus are presented as chronic cicatricial conjunctivitis. A correct differential diagnosis, as well as an early detection are essential for the control of this entity and its sequelae. Treatment, based on corticosteroids and immunosuppressants, both topical and systemic, is aimed at controlling inflammation and scarring.

本文旨在根据一例病例报告继发于眼部扁平苔藓的糜烂性角结膜炎的临床特征和治疗方法。患者是一名 77 岁的女性,有眼部不适和反复发作的角结膜炎病史,经保守治疗后病情未见好转,并有口腔和鼻腔溃疡病史。经过全面的眼科、皮肤科和解剖病理学检查后,确定了眼扁平苔藓的诊断,并开始了免疫抑制治疗。正确的鉴别诊断和早期发现对于控制这种疾病及其后遗症至关重要。以皮质类固醇和免疫抑制剂为基础的局部和全身治疗旨在控制炎症和瘢痕形成。
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引用次数: 0
Presunta maculopatía bilateral asociada a fluoxetina 推测与氟西汀相关的双侧黄斑病变
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.03.003

To report a unique case of a patient who developed simultaneous bilateral maculopathy presumed from intake of fluoxetine. The optic coherence tomography (OCT) macular showed a subfoveal disruption in the outer retinal layer in both eyes (OU), higher in the left one (OS). Although reported cases of serotonin recapture inhibitors (SSRIs) Maculopathy so far have been caused by sertraline, fluoxetine shares the biological mechanism, and OCT findings and ocular symptoms are the same as published. We should be aware with ocular symptoms in patients that take fluoxetine.

报告一个独特的病例,该患者因服用氟西汀而同时出现双侧黄斑病变。黄斑光学相干断层扫描(OCT)显示,患者双眼(OU)的视网膜外层都出现了眼窝下破坏,其中左眼(OS)的破坏程度更高。尽管迄今报道的5-羟色胺再捕获抑制剂(SSRIs)黄斑病变病例均由舍曲林引起,但氟西汀与之具有相同的生物学机制,且OCT结果和眼部症状与已发表的病例相同。我们应该注意服用氟西汀患者的眼部症状。
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引用次数: 0
Tortuosidad venosa en fondo ojo en síndrome de O’Donnel-Luria-Rodan (ODLURO): estudio con tomografía de coherencia óptica angiográfica tipo Swept Source (SS-OCT) o'Donnel-Luria-Rodan 综合征 (ODLURO) 中的静脉迂曲:利用扫源光学相干断层扫描 (SS-OCT) 进行的研究。
Q3 Medicine Pub Date : 2024-08-01 DOI: 10.1016/j.oftal.2024.03.014
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引用次数: 0
期刊
Archivos De La Sociedad Espanola De Oftalmologia
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