Pub Date : 2018-08-09DOI: 10.4066/2249-622X-C2-006
M. Mahgoub
{"title":"Biochemical and biological effects of irisin in a model of diabetes mellitus","authors":"M. Mahgoub","doi":"10.4066/2249-622X-C2-006","DOIUrl":"https://doi.org/10.4066/2249-622X-C2-006","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85866592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X.65.18-845
A. Shahi, Prasad Vss, S. Imam, Abdul Muheem, M. Jahangir
Diabetes is a chronic hyperglycaemic disorder. Due to altered metabolism of insulin and related pathways, consistently raised blood glucose levels leads to manifestation of collateral pathophysiologies or complications. Such long term complications include cardiovascular diseases, nephropathy, neuropathy and retinopathy. Microvascular complications are the major cause of these pathologies. Understanding the etiology of these complications is important to devise effective prevention and treatment strategies. Therefore, the current review was undertaken to enumerate various diabetes related pathologies, the relevant mechanisms, disease progression and available treatment options. The data was collected from major indexing services like-PubMed, Scopus, Google Scholar and some related journals which fall under the scope of the review paper. The major keywords which were used for the collection of data include diabetes, pathophysiology of diabetes, comorbidities of diabetes, diabetes complications, diabetes management, diagnosis of diabetes, diagnosis of comorbidities of diabetes etc. Most of the articles referred are published in last 8 years. However, some relevant articles are also considered which are published before this time frame.
糖尿病是一种慢性高血糖疾病。由于胰岛素代谢及相关途径的改变，持续升高的血糖水平可导致侧枝病理生理或并发症的表现。这些长期并发症包括心血管疾病、肾病、神经病变和视网膜病变。微血管并发症是这些病变的主要原因。了解这些并发症的病因对于制定有效的预防和治疗策略非常重要。因此，本综述旨在列举各种糖尿病相关病理、相关机制、疾病进展和可用的治疗方案。数据收集自主要的索引服务，如pubmed, Scopus, Google Scholar和一些相关的期刊，这些都属于综述论文的范围。收集资料时使用的主要关键词有糖尿病、糖尿病病理生理、糖尿病合并症、糖尿病并发症、糖尿病管理、糖尿病诊断、糖尿病合并症诊断等。大部分被引用的文章都是近8年发表的。然而，在此时间框架之前发表的一些相关文章也被考虑在内。
{"title":"Pathophysiological Ramifications of Diabetic Condition: A Review","authors":"A. Shahi, Prasad Vss, S. Imam, Abdul Muheem, M. Jahangir","doi":"10.4066/2249-622X.65.18-845","DOIUrl":"https://doi.org/10.4066/2249-622X.65.18-845","url":null,"abstract":"Diabetes is a chronic hyperglycaemic disorder. Due to altered metabolism of insulin and related pathways, consistently raised blood glucose levels leads to manifestation of collateral pathophysiologies or complications. Such long term complications include cardiovascular diseases, nephropathy, neuropathy and retinopathy. Microvascular complications are the major cause of these pathologies. Understanding the etiology of these complications is important to devise effective prevention and treatment strategies. Therefore, the current review was undertaken to enumerate various diabetes related pathologies, the relevant mechanisms, disease progression and available treatment options. The data was collected from major indexing services like-PubMed, Scopus, Google Scholar and some related journals which fall under the scope of the review paper. The major keywords which were used for the collection of data include diabetes, pathophysiology of diabetes, comorbidities of diabetes, diabetes complications, diabetes management, diagnosis of diabetes, diagnosis of comorbidities of diabetes etc. Most of the articles referred are published in last 8 years. However, some relevant articles are also considered which are published before this time frame.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"14 1","pages":"28-38"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85068998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X-C4-011
M. M. Rahman
{"title":"Separation of tin from tellurium: Effects of chloride and sulfate interferences","authors":"M. M. Rahman","doi":"10.4066/2249-622X-C4-011","DOIUrl":"https://doi.org/10.4066/2249-622X-C4-011","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76016616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622x-c4-010
M. El-Sayed
{"title":"Sorption and chromatography processes in environmental and biochemical applications","authors":"M. El-Sayed","doi":"10.4066/2249-622x-c4-010","DOIUrl":"https://doi.org/10.4066/2249-622x-c4-010","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87067603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X.65.18-644
Mohammad Mt, Mahdi Sk, Zahra T, Ahmad S, Mohammad Ka, Akram M, Hamid Rj
Background: Herbal drugs have been used to treat several diseases from liver and neural disorders to diabetes. Our study was aimed to find out the effects of alcoholic ginger extract on testis/body weight and apoptosis of sperm germ cells of chronic diabetic rat. Methods: In this experimental study, sixty male Wistar rats were randomly divided into 5 groups: nontreatment normal (group 1), non-treatment diabetic (group 2), ginger treatment diabetic (group 3), insulin treatment diabetic (group 4) and ginger plus insulin treatment diabetic (group 5). Ginger alcohol extract was injected intraperitoneally at the dose of 200 mg/kg for 6 weeks. TUNEL method was employed to evaluate the germ cells apoptosis. Expression of Bax, Bcl-2, CyclinD1, TRPV1, TLR2 and TLR4 was evaluated using Real-Time PCR technique. Results: Results revealed a significant decrease in the apoptosis index in the group 5 with respect to the group 2 (P<0.05). The expression of BAX, BCL2, TRPV1, TLR2 and TLR4 significantly decreased, while CYC D1 was increased in the group 5 in comparison to group 2. Conclusions: These results suggest ginger has a potentially beneficial role in reducing apoptosis and inflammation in testicular germ cells in chronic diabetic adult rats.
{"title":"The Effect of Alcoholic Extract of Ginger on Apoptosis and Inflammation of Germ Cells in Streptozotocin-Induced Diabetic Rats","authors":"Mohammad Mt, Mahdi Sk, Zahra T, Ahmad S, Mohammad Ka, Akram M, Hamid Rj","doi":"10.4066/2249-622X.65.18-644","DOIUrl":"https://doi.org/10.4066/2249-622X.65.18-644","url":null,"abstract":"Background: Herbal drugs have been used to treat several diseases from liver and neural disorders to diabetes. Our study was aimed to find out the effects of alcoholic ginger extract on testis/body weight and apoptosis of sperm germ cells of chronic diabetic rat. Methods: In this experimental study, sixty male Wistar rats were randomly divided into 5 groups: nontreatment normal (group 1), non-treatment diabetic (group 2), ginger treatment diabetic (group 3), insulin treatment diabetic (group 4) and ginger plus insulin treatment diabetic (group 5). Ginger alcohol extract was injected intraperitoneally at the dose of 200 mg/kg for 6 weeks. TUNEL method was employed to evaluate the germ cells apoptosis. Expression of Bax, Bcl-2, CyclinD1, TRPV1, TLR2 and TLR4 was evaluated using Real-Time PCR technique. Results: Results revealed a significant decrease in the apoptosis index in the group 5 with respect to the group 2 (P<0.05). The expression of BAX, BCL2, TRPV1, TLR2 and TLR4 significantly decreased, while CYC D1 was increased in the group 5 in comparison to group 2. Conclusions: These results suggest ginger has a potentially beneficial role in reducing apoptosis and inflammation in testicular germ cells in chronic diabetic adult rats.","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"69 1","pages":"14-20"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86400664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X-C1-001
Damien Byas
{"title":"INVESTIGATING HEALTH OUTCOMES ASSOCIATED WITH OBESITY RATES IN CHILDREN AND ADULTS","authors":"Damien Byas","doi":"10.4066/2249-622X-C1-001","DOIUrl":"https://doi.org/10.4066/2249-622X-C1-001","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85632802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X-C2-005
D. Shokry
{"title":"PATTERN OF PEDIATRIC POISONING IN EGYPT- CASES ADMITTED TO NATIONAL POISONING CONTROL CENTER","authors":"D. Shokry","doi":"10.4066/2249-622X-C2-005","DOIUrl":"https://doi.org/10.4066/2249-622X-C2-005","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78805407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X-C3-009
Kisok Kim
{"title":"CHARACTERIZATION OF PHENOLIC ACIDS AND FLAVONOIDS IN ETHYL ACETATE FRACTION OF ASTER GLEHNI","authors":"Kisok Kim","doi":"10.4066/2249-622X-C3-009","DOIUrl":"https://doi.org/10.4066/2249-622X-C3-009","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72673828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622x-c5-014
Haidar Muad Gamil, S. Ahmed
{"title":"RIGHT COLON ADENOCARCINOMA MISDIAGNOSED AND TREATED AS COMPLICATED APPENDICITIS IN ADULT PATIENTS: CASE REPORT","authors":"Haidar Muad Gamil, S. Ahmed","doi":"10.4066/2249-622x-c5-014","DOIUrl":"https://doi.org/10.4066/2249-622x-c5-014","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86769550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4066/2249-622X-C3-007
I. Archakova
{"title":"PHOSPHOLIPID MICELLES AS THE MEDICINES THEMSELVES AND DRUG DELIVERY SYSTEM","authors":"I. Archakova","doi":"10.4066/2249-622X-C3-007","DOIUrl":"https://doi.org/10.4066/2249-622X-C3-007","url":null,"abstract":"","PeriodicalId":8517,"journal":{"name":"Asian Journal of Biomedical and Pharmaceutical Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80086482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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