Asian journal of psychiatry最新文献

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PrecInNor: An Indo-Norway collaborative programme for precision psychiatry training PrecInNor：印度-挪威精确精神病学培训合作项目。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-10 DOI: 10.1016/j.ajp.2026.104852

Satish Suhas, Pravesh Parekh, Vanteemar S Sreeraj, Biju Viswanath, Srdjan Djurovic, Oleksandr Frei, Alexey A. Shadrin, Olav Bjerkehagen Smeland, Torill Ueland, Christine Lycke Brandt, Elisabeth Strand Vigtel, Reeteka Sud, Meera Purushottam, Ajay Kumar, M. Manjula, Anita Mahadevan, Ganesan Venkatasubramanian, Paulomi Matam Sudhir, John P. John, Ole A. Andreassen

引用次数: 0

Outcome of first episode and relapsing patients with schizophrenia presenting to a tertiary care hospital in Sri Lanka: A prospective one year follow up study 斯里兰卡一家三级医院首次发作和复发精神分裂症患者的结局：一项为期一年的前瞻性随访研究

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-09 DOI: 10.1016/j.ajp.2026.104842

Madhubhashinee Dayabandara , Prasad Liyanage , Eric Tian , Gary Remington , Varuni De Silva , Raveen Hanwella

Background

This study aimed to describe symptomatic and functional outcomes over 12 months for two cohorts of patients with schizophrenia in Sri Lanka.

Methodology

A prospective observational study was conducted among two cohorts of patients (first episode/FEC=122, relapsing/REC=118) aged 15–60 years diagnosed with schizophrenia in the University Psychiatry Unit, National Hospital of Sri Lanka. Patients with schizoaffective, other psychotic or organic disorders were excluded. Assessments conducted at baseline, 6 and 12 months included sociodemographic and clinical details, Positive and Negative Syndrome Scale, Centre for Epidemiological Studies Depression Scale, and WHO Psychiatric Disability Assessment Schedule. Remission followed the Remission in Schizophrenia Working Group criteria. Recovery included remission, independent living and employment.

Results

Cohorts were similar except in age distribution and substance use. Mortality was 0.8 % over 12 months. Relapse rates were similar for both cohorts (21–25 %). The FEC showed significantly higher remission (60–65 %) and recovery (45–47 %) compared with REC (remission: 38–48 %, recovery: 21–27 %) at 6- and 12-months. Sustained recovery over 12 months ranged from 13 % to 33 %. FEC presented with more severe symptoms and functional impairment at baseline but showed steeper improvement. Depression prevalence was 83 % in both cohorts at baseline. Employment significantly increased from 43 % to 53 % in FEC remaining stable for REC at 42 %. Medication non-adherence was higher in FEC (20–38 %), main reasons being forgetfulness and beliefs of non-necessity.

Conclusions

Schizophrenia outcomes remain favourable in Sri Lanka. First episode patients achieve better symptom improvement and functional gains. Early use of long-acting injectable antipsychotics, legislative reforms, psychoeducation, and family involvement may help sustain these favourable outcomes.

本研究旨在描述斯里兰卡两组精神分裂症患者在12个月内的症状和功能结局。方法对斯里兰卡国立医院大学精神科15-60岁确诊为精神分裂症的两组患者（首发/FEC=122，复发/REC=118）进行前瞻性观察研究。患有分裂情感性、其他精神或器质性障碍的患者被排除在外。在基线、6个月和12个月进行的评估包括社会人口学和临床细节、阳性和阴性综合征量表、流行病学研究中心抑郁量表和世卫组织精神残疾评估表。缓解遵循精神分裂症工作组的缓解标准。康复包括缓解、独立生活和就业。结果各年龄组除年龄分布和药物使用情况外，无明显差异。12个月内死亡率为0.8 %。两组患者的复发率相似（21-25 %）。FEC在6个月和12个月时的缓解率（60-65 %）和恢复率（45-47 %）明显高于REC（缓解率：38-48 %，恢复率：21-27 %）。12个月的持续回收率从13 %到33 %不等。FEC在基线时表现为更严重的症状和功能损害，但改善更迅速。基线时，两个队列的抑郁症患病率均为83% %。就业显著增加，从43 %到53 %，FEC保持稳定，为42 %。FEC的药物依从性较高（20-38 %），主要原因是遗忘和认为没有必要。结论：斯里兰卡精神分裂症患者的预后仍然良好。首发患者可获得较好的症状改善和功能改善。早期使用长效注射抗精神病药物、立法改革、心理教育和家庭参与可能有助于维持这些有利结果。

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引用次数: 0

Efficacy and side effects of antipsychotic drugs in schizophrenic patients with comorbid chronic illness 抗精神病药物治疗合并慢性疾病的精神分裂症患者的疗效和副反应。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-09 DOI: 10.1016/j.ajp.2026.104846

Qiuyue Peng , Haixin Li , Qingxing Lu, Mengtong Xie, Hongyi Ren, Wen-Yan Tan, Fu-Jun Jia, Qiong Yu , Shi-Bin Wang

引用次数: 0

Psychotherapy teaching and training for Indian medical undergraduates: Needs and challenges 印度医学本科生心理治疗教学与培训：需求与挑战

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-09 DOI: 10.1016/j.ajp.2026.104849

Sujita Kumar Kar, Swapnajeet Sahoo

引用次数: 0

Acupuncture as adjunctive treatment for schizophrenia: a systematic review and meta-analysis 针灸作为精神分裂症的辅助治疗：一项系统回顾和荟萃分析

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-08 DOI: 10.1016/j.ajp.2026.104844

Yujin Choi , Boram Lee , Pyung-Wha Kim , A.-La Park , Seung-Hun Cho

Background

Schizophrenia spectrum disorders significantly impair functioning and quality of life. While antipsychotic medications are the cornerstone of treatment, many patients experience persistent symptoms and adverse effects. The potential benefits of acupuncture as adjunctive treatment remain uncertain.

Methods

Nine databases including MEDLINE, EMBASE, and CENTRAL were searched through 15 January 2025. Randomised controlled trials comparing acupuncture plus antipsychotics versus antipsychotics alone in patients with schizophrenia spectrum disorders were included. The primary outcome was overall symptom scores (PANSS/BPRS). Secondary outcomes included adverse events, negative and positive symptom scores, response rates, social function, and quality of life. Risk of bias was assessed using the Cochrane Risk of Bias 2 tool, a random-effects model was applied for meta-analysis, and evidence certainty was evaluated using GRADE.

Results

Fifty-five studies with 4256 participants were included. Acupuncture plus standard-dose antipsychotics improved overall symptoms compared to antipsychotics alone (SMD −1.11, 95 % CI −1.52 to −0.70; 34 studies, 2819 participants; low certainty), but not versus sham acupuncture (MD −0.89, 95 % CI −2.72–0.95; 2 studies, 91 participants; low certainty). Adverse events were reduced versus antipsychotics alone (RR 0.44, 95 % CI 0.33–0.59; 7 studies, 862 participants; moderate certainty). Acupuncture plus low-dose antipsychotics showed little to no difference versus standard-dose antipsychotics alone (SMD −0.47, 95 % CI −1.56–0.61; 8 studies, 532 participants; very low certainty).

Conclusions

Acupuncture combined with standard-dose antipsychotics may provide pragmatic benefits, though lack of superiority over sham acupuncture indicates uncertainty about specific effects. High-quality trials are needed to establish definitive clinical recommendations.

精神分裂症谱系障碍显著损害功能和生活质量。虽然抗精神病药物是治疗的基石，但许多患者会经历持续的症状和不良反应。针灸作为辅助治疗的潜在益处仍不确定。方法检索截至2025年1月15日的MEDLINE、EMBASE和CENTRAL数据库。包括比较针灸加抗精神病药物与单独抗精神病药物治疗精神分裂症谱系障碍患者的随机对照试验。主要终点是总体症状评分（PANSS/BPRS）。次要结局包括不良事件、阴性和阳性症状评分、反应率、社会功能和生活质量。采用Cochrane Risk of bias 2工具评估偏倚风险，采用随机效应模型进行meta分析，采用GRADE评估证据确定性。结果共纳入55项研究，4256名受试者。与单独使用抗精神病药物相比，针灸加标准剂量抗精神病药物改善了整体症状（SMD - 1.11, 95 % CI - 1.52至- 0.70；34项研究，2819名受试者；低确定性），但与假针灸相比没有改善（MD - 0.89, 95 % CI - 2.72-0.95； 2项研究，91名受试者；低确定性）。与单独使用抗精神病药物相比，不良事件减少（RR 0.44, 95 % CI 0.33-0.59； 7项研究，862名受试者；中等确定性）。针灸加低剂量抗精神病药物与单独使用标准剂量抗精神病药物相比，几乎没有差异（SMD - 0.47, 95 % CI - 1.56-0.61； 8项研究，532名受试者；极低确定性）。结论针刺联合标准剂量抗精神病药物可能具有实际疗效，但与假针相比缺乏优势，具体效果尚不确定。需要高质量的试验来建立明确的临床建议。

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引用次数: 0

A policy perspective on suicide prevention: Gaps in Indonesia’s educational and public health systems 自杀预防的政策视角：印尼教育和公共卫生系统的差距

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-08 DOI: 10.1016/j.ajp.2026.104847

Muhammad Farid Ma’ruf, Ajie Hanif Muzaqi, Nuh Krama Hadianto

引用次数: 0

The clue on the bleeding face: Unpacking MiTES (midface toddler excoriation syndrome) through genetics and behaviour 流血的脸上的线索：通过遗传和行为来去除螨虫（脸中部幼儿擦伤综合征）

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-08 DOI: 10.1016/j.ajp.2026.104848

Srivastava Akash , Bhatnagar Priyanka, P.K. Pardal

引用次数: 0

Is loneliness related to greater use of DeepSeek as an AI companion? A study from China 孤独感是否与深度搜索作为人工智能伴侣的更多使用有关？一项来自中国的研究。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-08 DOI: 10.1016/j.ajp.2026.104845

Christian Montag, Wang Yao, Zhiying Zhao, Jon D. Elhai, Shujun Liu, Haibo Yang

引用次数: 0

A culturally embedded digital–community paradigm for mental health in the Middle East: A conceptual letter toward system-level transformation 中东心理健康的文化嵌入式数字社区范式：迈向系统级转型的概念性信函

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-07 DOI: 10.1016/j.ajp.2026.104841

Mahdi Naeim, Mohammad Narimani

引用次数: 0

Evaluating auditory semantic and prosodic content, lexical acquisition, and facial identification as perceptual determinants of emotion recognition in schizophrenia 评估听觉语义和韵律内容、词汇习得和面部识别作为精神分裂症情绪识别的知觉决定因素

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2026-01-07 DOI: 10.1016/j.ajp.2026.104837

Ishita Dhyani , Stuti Karna , Sonali Singhal , Shubham Narnoli , Panna Sharma , Ragul Ganesh , Rohit Verma

Background

Emotion recognition is essential for both general wellbeing and social relationships. This ability is compromised in individuals suffering from schizophrenia. However, not all aspects of emotion recognition have been evaluated in previous literature.

Aim

The present study aimed to evaluate emotion recognition through auditory semantic and prosodic content, lexical acquisition and facial identification in individuals suffering from schizophrenia compared to healthy individuals.

Methods

This cross-sectional study included 50 individuals diagnosed with schizophrenia along with age and handedness matched 50 healthy individuals were assessed using Edinburgh Handedness Inventory (EHI), Verbal Adult Intelligence Scale (VAIS), Scale for Assessment of Negative Symptoms (SANS), Scale for Assessment of Positive Symptoms (SAPS), and Extrapyramidal Symptoms Rating Scale (ESRS). Four types of emotion recognition tasks were presented to the participants - lexical, visual (static facial images and dynamic videos), and auditory. Autonomic functions were evaluated that included testing of systolic blood pressure (SBP), diastolic blood pressure (DBP) and pulse rate (PR) of the participants before and after the completion of each emotion recognition task.

Results

There were differences in performance observed for people with schizophrenia when compared to healthy individuals. This was noticeable across all the different types of perceptual dimensions – lexical, visual (static facial images and dynamic videos), and auditory. Additionally, after completing an emotion detection task, there was a change in autonomic functioning that was significantly more pronounced in people with schizophrenia.

Conclusion

The findings indicate that individuals with schizophrenia have difficulty in emotion recognition for all perceptual modalities.

降级认知对于整体幸福感和社会关系都是至关重要的。这种能力在精神分裂症患者身上受到损害。然而，在以往的文献中，并不是所有方面的情绪识别都被评估过。目的比较精神分裂症患者与正常人在听觉语义韵律内容、词汇习得和面部识别等方面的情绪识别能力。方法采用爱丁堡利手性量表（EHI）、成人言语智力量表（VAIS）、阴性症状评定量表（SANS）、阳性症状评定量表（SAPS）和锥体外系症状评定量表（ESRS）对50例诊断为精神分裂症的患者进行年龄和利手性匹配的横断面研究。四种类型的情绪识别任务呈现给参与者——词汇、视觉（静态面部图像和动态视频）和听觉。评估自主神经功能，包括测试参与者在完成每项情绪识别任务前后的收缩压（SBP）、舒张压（DBP）和脉搏率（PR）。结果与健康个体相比，精神分裂症患者的表现存在差异。这在所有不同类型的感知维度上都是显而易见的——词汇、视觉（静态面部图像和动态视频）和听觉。此外，在完成一项情绪检测任务后，精神分裂症患者的自主神经功能发生了明显的变化。结论精神分裂症患者在所有知觉模态的情绪识别上都存在困难。

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