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Atypical neuropsychiatric withdrawal syndrome following abrupt cessation of chronic nitrous oxide use: A case report 突然停止慢性氧化亚氮使用后的非典型神经精神戒断综合征:一例报告。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104882
Chung Nguyen Viet , Bruce Boman , Chien Nguyen Huu , Quan Nguyen Trong
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引用次数: 0
A policy perspective on suicide prevention: Gaps in Indonesia’s educational and public health systems 自杀预防的政策视角:印尼教育和公共卫生系统的差距
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.ajp.2026.104847
Muhammad Farid Ma’ruf, Ajie Hanif Muzaqi, Nuh Krama Hadianto
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引用次数: 0
Psychotherapy teaching and training for Indian medical undergraduates: Needs and challenges 印度医学本科生心理治疗教学与培训:需求与挑战
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-09 DOI: 10.1016/j.ajp.2026.104849
Sujita Kumar Kar, Swapnajeet Sahoo
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引用次数: 0
Health literacy and the continuum of suicidal behaviors among adults: A national survey from South Korea, 2023 健康素养和成年人自杀行为的连续性:韩国2023年的一项全国性调查。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104884
Seong-Uk Baek, Jin-Ha Yoon
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引用次数: 0
Advancing psychotherapy in Malaysian psychiatric practice: The role of the psychotherapy chapter of the Malaysian Psychiatric Association 在马来西亚精神病实践中推进心理治疗:马来西亚精神病协会心理治疗分会的作用。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104877
Chong Seng Choi, Nik Ruzyanei Nik Jaafar
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引用次数: 0
PrecInNor: An Indo-Norway collaborative programme for precision psychiatry training PrecInNor:印度-挪威精确精神病学培训合作项目。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-10 DOI: 10.1016/j.ajp.2026.104852
Satish Suhas, Pravesh Parekh, Vanteemar S Sreeraj, Biju Viswanath, Srdjan Djurovic, Oleksandr Frei, Alexey A. Shadrin, Olav Bjerkehagen Smeland, Torill Ueland, Christine Lycke Brandt, Elisabeth Strand Vigtel, Reeteka Sud, Meera Purushottam, Ajay Kumar, M. Manjula, Anita Mahadevan, Ganesan Venkatasubramanian, Paulomi Matam Sudhir, John P. John, Ole A. Andreassen
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引用次数: 0
Acute Pisa syndrome in a 4-year-old child with autism spectrum disorder: The youngest reported case of risperidone-induced extrapyramidal reaction 急性比萨综合征的4岁儿童自闭症谱系障碍:最年轻的利培酮诱导锥体外反应的报告病例
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.ajp.2026.104838
Himanshu Garg, Abhishek Pandey, Neha Anushree, Shobit Garg , Karthik Ram Mohan

Background

Pisa syndrome is a rare extrapyramidal disorder characterized by sustained lateral flexion of the trunk, typically associated with antipsychotic medications. Though well-described in adult populations, its occurrence in children is exceedingly rare, with no previously reported cases in children under 12 years of age for drug-induced etiology.

Clinical description

We report the case of a 4-year-old boy with autism spectrum disorder (ASD), receiving risperidone (0.5 mL BID) for behavioural issues, on continued behavioural therapy, who developed acute onset painful lateral flexion of the trunk—clinically consistent with Pisa syndrome.

Management & outcome

He was promptly treated with intravenous pheniramine maleate, with immediate resolution of symptoms. Risperidone was discontinued, and no recurrence was noted on follow-up. Causality assessment using the Pediatric Naranjo Adverse Drug Reaction Probability Scale yielded a score of 7, indicating a probable adverse drug reaction to risperidone.

Conclusion

This case underscores the importance of early recognition of rare extrapyramidal side effects such as Pisa syndrome in children on atypical antipsychotics. Clinicians should maintain a high index of suspicion, even in very young children, and be aware of effective management strategies.
背景:pisa综合征是一种罕见的锥体外系疾病,以躯干持续侧屈为特征,通常与抗精神病药物有关。虽然在成人人群中有很好的描述,但在儿童中的发生极为罕见,以前没有12岁以下儿童因药物引起的病因的病例报道。临床描述:我们报告了一名患有自闭症谱系障碍(ASD)的4岁男孩,接受利培酮(0.5 mL BID)治疗行为问题,并继续接受行为治疗,他出现了急性发作的躯干疼痛侧屈-临床表现与Pisa综合征一致。处理和结果患者立即静脉注射马来酸苯那敏治疗,症状立即缓解。利培酮停用,随访未见复发。使用儿童纳兰霍药物不良反应概率量表进行因果关系评估,得分为7分,表明可能对利培酮产生不良反应。结论本病例强调了早期识别非典型抗精神病药物治疗中罕见的锥体外系副作用如比萨综合征的重要性。临床医生应保持高度的怀疑指数,即使在非常年幼的儿童,并意识到有效的管理策略。
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引用次数: 0
Ten sessions, faster response, or faster exit? Clarifying “Speed” and cost claims in piTBS vs 10-Hz rTMS 十个会话,更快的响应,还是更快的退出?澄清piTBS和10hz rTMS的“速度”和成本要求。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104881
Xiaowei Zhang
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引用次数: 0
Impaired task-switching in major depressive disorder: A time-frequency analysis of non-emotional and emotional stimuli 重度抑郁症的任务转换受损:非情绪和情绪刺激的时频分析。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104879
Kaili Zheng , Wanrong Peng , Zhaoxia Liu , Xiaoshuang Gu , Meiqian Tang , Weijun Situ , Jinyao Yi

Background

Major depressive disorder (MDD) is characterized by significant impairments in cognitive functions, including task-switching dysfunction. This study investigates the differences in switching impairments between non-emotional and emotional switching tasks in MDD patients and explores the underlying neuropsychological mechanisms.

Methods

48 MDD patients and 52 healthy controls (HCs) were recruited. Behavioral and electroencephalogram data were recorded while participants performed non-emotional and emotional task-switching paradigms. Event-related potentials (ERPs: P2, N2, P3 difference waves) and event-related spectral perturbations (ERSPs: theta, alpha, beta band power) were analyzed to assess group differences.

Results

In the magnitude task, MDD group displayed reduced occipital Pd2 amplitude (p < 0.001, η2p=0.20), increased frontal/central Pd3 amplitudes (p < 0.001, η2p=0.10), and larger alpha power differences (p < 0.05, η2p= 0.04). In the gender task, MDD group had increased occipital Pd2 amplitude (p < 0.05, η2p=0.04) and larger alpha power differences in the P3 time window (p < 0.01, η2p=0.03). In the emotion task, MDD group showed prolonged Pd2 latency (p < 0.05, η2p=0.04), reduced Pd3 amplitude (p < 0.05, η2p=0.10), smaller theta power differences (p = 0.05, η2p=0.03), and larger beta power differences (p < 0.05, η2p=0.04).

Conclusion

MDD patients exhibit a dissociable pattern of task-switching deficits across non-emotional and emotional task-switching scenarios, characterized by distinct abnormalities across early visual processing, conflict monitoring, cognitive resource allocation, and multi-stage emotional processing. This study reveals novel electrophysiological mechanisms underlying cognitive inflexibility in MDD.
背景:重度抑郁症(MDD)的特征是认知功能的显著损伤,包括任务转换功能障碍。本研究探讨重度抑郁症患者非情绪性和情绪性转换任务的转换障碍差异,并探讨其潜在的神经心理学机制。方法:选取48例重度抑郁症患者和52例健康对照。当参与者进行非情绪和情绪任务转换范式时,记录他们的行为和脑电图数据。分析事件相关电位(ERPs: P2、N2、P3差波)和事件相关谱扰动(ERSPs: θ、α、β波段功率)来评估组间差异。结果:在幅度任务中,MDD组枕部Pd2幅值降低(p 2p=0.20),额部/中央Pd3幅值增加(p 2p=0.10), alpha功率差异较大(p 2p= 0.04)。在性别任务中,MDD组枕部Pd2振幅增加(p 2p=0.04), P3时间窗α功率差异更大(p 2p=0.03)。在情绪任务中,MDD组Pd2潜伏期延长(p 2p=0.04), Pd3振幅减小(p 2p=0.10), θ功率差异较小(p = 0.05,η2p=0.03), β功率差异较大(p 2p=0.04)。结论:MDD患者在非情绪性和情绪性任务转换情景中表现出可分离的任务转换缺陷模式,其特征是在早期视觉加工、冲突监测、认知资源分配和多阶段情绪加工中表现出明显的异常。本研究揭示了重度抑郁症认知不灵活性的新电生理机制。
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引用次数: 0
The effectiveness of technology-based intervention programs in the prevention of child abuse: A systematic review and meta-analysis study 基于技术的干预方案在预防儿童虐待中的有效性:一项系统回顾和荟萃分析研究。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-07 DOI: 10.1016/j.ajp.2026.104887
Edanur Tar Bolacali , Gökçe Demir , Bahar Aksoy , Sevda Uzun
This study was conducted with the aim of revealing the effectiveness of technology-based intervention programs in the prevention of child abuse. For this systematic review and meta-analysis study, researches were obtained by searching PubMed, Web of Science, Scopus, Google Scholar and National Thesis Center of the Council of Higher Education databases without any year limitation. After the review, 18 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. In this systematic review and meta-analysis, it was found that technology-based intervention programs were effective in preventing child abuse in educators and caregivers (SMD: 0.673; 95% CI: 0.500–1.243; Z = 4.594, p = 0.00, (I2 = 77.6%). In addition, technology-based intervention programs were found to be effective in preventing child abuse in children SMD: 0.255 95% CI: −0.059 to 0.570; Z = 1.589, p = 0.112, (I2 = 59.6%) and parents (SMD: 0.194 95% CI: −0.584 to 0.973; Z = 0.490, p = 0.624, (I2= 97.6%). This study showed that technology-based intervention programs can play a beneficial and important role on individuals in the prevention of child abuse.
本研究旨在揭示以科技为基础的干预计划在预防虐待儿童方面的有效性。本系统综述和荟萃分析研究通过检索PubMed、Web of Science、Scopus、谷歌Scholar和美国高等教育委员会国家论文中心数据库获得研究结果,不受年份限制。回顾后,18项研究被纳入研究。采用元分析和叙述方法对数据进行综合。在本系统回顾和荟萃分析中,我们发现基于技术的干预方案在预防教育工作者和照顾者虐待儿童方面是有效的(SMD: 0.673; 95% CI: 0.500-1.243; Z = 4.594,p = 0.00,(I2 = 77.6%)。此外,以技术为基础的干预方案被发现在预防儿童SMD中虐待儿童方面是有效的:0.255 95% CI: -0.059至0.570;Z = 1.589,p = 0.112,(I2 = 59.6%)和家长(SMD: 0.194 - 95%置信区间:-0.584 - 0.973;Z = 0.490,p = 0.624,(I2 = 97.6%)。这项研究表明,以技术为基础的干预计划可以在预防儿童虐待方面对个人发挥有益和重要的作用。
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Asian journal of psychiatry
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