Asian journal of psychiatry最新文献

{"title":"Addressing the paradox of help-seeking reluctance among mental health professionals","authors":"Mohsen Khosravi","doi":"10.1016/j.ajp.2025.104819","DOIUrl":"10.1016/j.ajp.2025.104819","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104819"},"PeriodicalIF":4.5,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145881739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hemodialysis dramatically alleviates treatment-refractory psychosis in a subject with schizoaffective disorder","authors":"Yun-An Liu, Yi-Chyan Chen","doi":"10.1016/j.ajp.2025.104813","DOIUrl":"10.1016/j.ajp.2025.104813","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104813"},"PeriodicalIF":4.5,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145881740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The long-term clinical and functional outcomes of psychiatric patients with catatonia: A 5-year follow-up","authors":"Qi-Hang Zhang ,&nbsp;Tian Han ,&nbsp;Xiao-Xiao He ,&nbsp;Mathangie Gananathan ,&nbsp;Xiao-Lin Yin ,&nbsp;Hao-Tian Shen ,&nbsp;Fuchun Zhou ,&nbsp;Chuan-Yue Wang","doi":"10.1016/j.ajp.2025.104818","DOIUrl":"10.1016/j.ajp.2025.104818","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to compare the long-term clinical and functional outcomes between psychiatric patients with and without catatonia over a 5-year follow-up and to explore the baseline predictors of poor outcomes.</div></div><div><h3>Methods</h3><div>The study sample comprised 51 with catatonic and 56 non-catatonic psychiatric patients. Catatonia was assessed using the Bush-Francis Catatonia Rating Scale (BFCRS). We also determined serum high-sensitivity C-reactive protein (hs-CRP) levels at the baseline, recorded clinical outcomes during follow-up, and assessed the Global Assessment of Functioning (GAF) scale at endpoint.</div></div><div><h3>Results</h3><div>Follow-up data were available for 31 catatonic patients and 34 non-catatonia patients. During follow-up, the catatonic group had a significantly higher percentage of treatment-resistant cases compared to the non-catatonic group (25.8 % vs. 5.9 %). Catatonic patients had significantly more readmissions than non-catatonic patients after excluding patients with poor adherence. At the endpoint, patients in the catatonic group scored significantly lower on the GAF than those in the non-catatonic group. In the catatonic group, patients with high inflammatory levels had a significantly higher number of readmissions than those with low inflammatory levels. In the whole sample, multiple linear regression analyses revealed that baseline BFCRS scores were a significant and independent predictor of poor functional outcome at follow-up (Beta = −0.369, P = 0.002, 95 % CI: −0.008 to −0.002).</div></div><div><h3>Conclusion</h3><div>Findings suggest that catatonia is linked to poorer clinical outcomes and a lower level of functioning. Specifically, baseline high inflammatory levels seem to contribute to a higher relapse rate in catatonic patients.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104818"},"PeriodicalIF":4.5,"publicationDate":"2025-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145916664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are social robots more interesting than humans? Quantitative assessment of Joint Attention in autistic and typically developing children","authors":"Silvia Annunziata ,&nbsp;Gabriele Fassina ,&nbsp;Michelle Brivio ,&nbsp;Laura Santos ,&nbsp;Emilia Ambrosini ,&nbsp;Paolo Meriggi ,&nbsp;Paola Molina ,&nbsp;Alessandra Pedrocchi ,&nbsp;Anna Cavallini","doi":"10.1016/j.ajp.2025.104796","DOIUrl":"10.1016/j.ajp.2025.104796","url":null,"abstract":"<div><h3>Introduction</h3><div>Autism Spectrum Disorder (ASD) is characterized by deficits in social interaction and communication, including joint attention (JA) impairment. This observational case-control study explores quantitative JA metrics in ASD preschool-aged children and typically-developing (TD) toddlers, interacting with both a human agent and a social robot.</div></div><div><h3>Material and methods</h3><div>Ten ASD and sixteen Typically Developing (TD) children, matched for developmental age, participated completing two JA tasks of the “Échelle par la Communication Sociale Precoce”(ECSP)-Gaze Following and Object Spectacle-administered by both a human (ECSP-H) and a social robot NAO (ECSP-R). A Kinect Azure Camera was used to track children's gaze and five performance indicators were defined to quantify JA-related behaviors: Number of Responses to JA, Time Latency to response and Fixation Time, both towards robot and human agent.</div></div><div><h3>Results</h3><div>Significant group differences emerged in responsiveness to social cues, particularly in the Gaze Following task. TD children responded more consistently to human prompts (p = 0.01) and showed greater visual interest in the human agent in both ECSP-H (p &lt; 0.01) and ECSP-R (p = 0.02) conditions. In contrast, percentage of fixations on the robot was comparable across groups.</div></div><div><h3>Discussion</h3><div>This study introduces unobtrusive, gaze-based quantitative measures to assess joint attention in ASD. Significant differences between ASD and TD groups suggest that children with ASD exhibited greater attentional preference to the robot agent, giving potential for these metrics in distinguishing attentional patterns in these two populations. This feature may nonetheless be clinically relevant, as it may be leveraged to facilitate attention, promote participation, and support robot-assisted therapeutic interventions.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104796"},"PeriodicalIF":4.5,"publicationDate":"2025-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145916705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new approach in autism diagnosis: Evaluating natural interaction using point of view (POV) glasses","authors":"Hakan Kayış ,&nbsp;Murat Çelik ,&nbsp;Çınar Gedizlioğlu ,&nbsp;Elif Kayış ,&nbsp;Cumhur Aydemir ,&nbsp;Arda Hatipoğlu ,&nbsp;Seda Sarı ,&nbsp;Nurhak Dogan ,&nbsp;Elif Mumcu ,&nbsp;Rabia Arı ,&nbsp;Burcu Özbaran","doi":"10.1016/j.ajp.2025.104798","DOIUrl":"10.1016/j.ajp.2025.104798","url":null,"abstract":"<div><div>This study introduces an AI-assisted method based on examiner-worn Point of View (POV) glasses and computer vision analysis to provide objective behavioral data for the diagnosis of Autism Spectrum Disorder (ASD). The study included 29 children with ASD and 27 children without ASD, aged between 17 and 36 months. During semi-structured naturalistic interactions, the examiner wore POV glasses equipped with a scene camera that captured the child’s face from an eye-level perspective, preserving ecological validity. Behavioral parameters—including facial expressions, approximate social gaze (operationalized as the child’s eyes orientation toward the POV camera), and head mobility—were extracted using OpenFace and MediaPipe and subsequently analyzed with machine learning techniques. Statistical analyses revealed that total social gaze duration, longest social gaze, social smiling, number of responses to name, response latency, response duration, social responsiveness, and head movements along the z-axis had p-values ≤ 0.05, while head movements on the x- and y-axes, total head movement, and rapid head movements had p-values &gt; 0.05. The classification model developed using decision trees and the AdaBoost algorithm demonstrated high performance, achieving an accuracy of 91.07 % and a sensitivity of 89.65 %. These findings support the clinical applicability of examiner-worn POV recordings for early ASD detection and highlight their potential to complement traditional, subjective assessment methods.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104798"},"PeriodicalIF":4.5,"publicationDate":"2025-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145839146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pre-treatment brain morphology predicts symptom-specific outcomes in paediatric emotional disorders","authors":"Chengrong Hua ,&nbsp;Wenjing Liu ,&nbsp;Zhen Liu ,&nbsp;Changminghao Ma ,&nbsp;Zhishan Hu ,&nbsp;Yue Ding ,&nbsp;Kelun Yaoma ,&nbsp;Jiayi Song ,&nbsp;Yang Sun ,&nbsp;Fang Zhang ,&nbsp;Yue Liu ,&nbsp;Yi Huang ,&nbsp;Yingying Tang ,&nbsp;Xiaochen Zhang ,&nbsp;Wenhong Cheng","doi":"10.1016/j.ajp.2025.104797","DOIUrl":"10.1016/j.ajp.2025.104797","url":null,"abstract":"<div><h3>Background</h3><div>Depressive and anxiety disorders commonly co-occur in paediatric patients, but treatment response varies widely. Brain morphometric features may provide prognostic markers for symptom-specific outcomes and guide personalised interventions. This study examined whether pre-treatment brain morphology predicts improvement after inpatient treatment in adolescents with emotional disorders.</div></div><div><h3>Methods</h3><div>Adolescents with major depressive disorder and/or anxiety disorders admitted to a specialised psychiatric hospital underwent magnetic resonance imaging (MRI) before comprehensive inpatient treatment, including pharmacotherapy and psychotherapy (approximately 4–6 weeks, n = 66). Treatment response was assessed by percentage reductions in the Children’s Depression Inventory (CDI) and Screen for Child Anxiety Related Emotional Disorders (SCARED) total scores. Backward stepwise regression was performed separately for depressive and anxiety symptom improvement, focusing on predefined morphometric features associated with depressive or anxiety disorder derived from prior large-scale neuroanatomical findings.</div></div><div><h3>Results</h3><div>Among 66 adolescents, significant reductions in CDI and SCARED scores were observed over inpatient treatment. Regression analyses showed that larger pre-treatment surface area of the right postcentral gyrus was associated with greater improvement in depressive symptoms (slope=0.022; 95 % CI, 0.004–0.040; β=0.319; p = 0.016; n = 57), while smaller surface area of the left temporal pole (slope=–0.179; 95 % CI, –0.314 to –0.044; β=–0.304; p = 0.010; n = 64) and larger surface` area of the right frontal pole (slope=0.245; 95 % CI, 0.013–0.477; β=0.238; p = 0.039; n = 64) was associated with greater improvement in anxiety symptoms.</div></div><div><h3>Conclusion</h3><div>Pre-treatment morphometric features may serve as distinct neuroanatomical markers predicting symptom-specific response to inpatient treatment in paediatric emotional disorders, supporting the role of brain-based biomarkers in improving therapeutic outcomes.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104797"},"PeriodicalIF":4.5,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145814181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Amalgamating artificial intelligence & neuropsychiatry: Multimodal approach for precision diagnosis","authors":"Mugdha Tendulkar ,&nbsp;Reshma Tendulkar","doi":"10.1016/j.ajp.2025.104795","DOIUrl":"10.1016/j.ajp.2025.104795","url":null,"abstract":"<div><div>Human body is an intricate system of complex associations between numerous chemicals, neurotransmitters incessantly striving towards homeostasis. This process is so tightly regulated that these processes quickly reverse the alterations caused due to any insults suffered by the organism; when these repeatedly attack the organism’s system, they culminate as diseases. Brain being the hub of such complex interplay, is the most vulnerable site for such imbalances. As per 2021 World Health Organisation Report, over 3 billion of the global population live with a neuropsychiatric ailment. Owing to the extremely limited options for diagnosis in neuropsychiatry, it is tedious to arrive at a definitive diagnosis early. Normally, diagnosis of neuropsychiatric disorders like autism spectrum disorder, generalized anxiety disorders, obsessive compulsive disorder, schizophrenia etc. demands persistence of symptoms for over 6 months with no body fluid test to appropriately quantify the diagnosis, it demands the need for a novel approach for bridging this significant gap. With the ever-advancing technological era, the advent of artificial intelligence has revolutionized the medical paradigm. Integration of such multimodal neuroimaging databases, algorithms, techniques has made individualized diagnosis &amp; treatment of neuropsychiatric disorders plausible. Considering the colossal data revolving around artificial intelligence neuroimaging, particularly address disease-specific challenges &amp; rarely collate how multimodal frameworks amalgamate neurology &amp; psychiatric disorders. In addition, no prior literature systematically compares biomarker-rich &amp; scare diseases &amp; emphasizes the challenges faced by artificial intelligence among these groups. This review bridges this research gap by presenting an integrated, comprehensible manuscript which links multimodal networks of supervised, unsupervised, reinforcement learning models across the whole of neuropsychiatric spectrum. The novelty of this manuscript lies in highlighting the transdiagnostic perspectives of multimodal approaches of neuroimaging which are artificial intelligence-driven. This aids in filling the gaps between psychiatric &amp; neurological disorders thereby practically focussing on the blueprint towards precision diagnostic models- an entirely understudied aspect in previous literatures. The primary aim of this manuscript is to explore the fusion between the multimodal approach of artificial intelligence &amp; neuropsychiatric diagnosis, their implications, and challenges faced in this integration. We meticulously analyze the applications of artificial intelligence in precision medicine in the field of neuropsychiatry to ensure timely diagnosis and prevent complications, to improve patients’cost of living, prognosis as well as future directions of this amalgamation.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"115 ","pages":"Article 104795"},"PeriodicalIF":4.5,"publicationDate":"2025-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145817596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A systematic review of social media impact on psychological well-being among children, adolescents, and young adults in arab countries","authors":"Amani N. Alansari ,&nbsp;Abdallah Alwawi ,&nbsp;Amani Salim ,&nbsp;Nizar Tarawah ,&nbsp;Amine Ksia ,&nbsp;Mohamed Sayed Zaazouee","doi":"10.1016/j.ajp.2025.104793","DOIUrl":"10.1016/j.ajp.2025.104793","url":null,"abstract":"<div><h3>Background</h3><div>Social media is a major part of daily life for youth worldwide, including in Arab countries. Although it offers avenues for connection and information, growing concerns exist around its psychological impacts. This review aims to synthesize existing evidence on the association between social media use and mental health outcomes among children, adolescents, and young adults in Arab countries.</div></div><div><h3>Methods</h3><div>We systematically searched PubMed, Scopus, EMBASE, and Web of Science for peer-reviewed studies published until October 2025. Inclusion criteria targeted observational studies involving participants aged ≤ 25 years from Arab League countries, focusing on the relationship between social media use and mental health indicators. Data were extracted and quality assessed using the Newcastle-Ottawa Scale adaptation for cross-sectional designs.</div></div><div><h3>Results</h3><div>Twenty-one cross-sectional studies, encompassing over 15,000 participants with a mean age ranging from 13 to 25 years and representing multiple Arab countries, met the inclusion criteria. Findings revealed consistent associations between high or problematic social media use and adverse mental health outcomes, including anxiety, depression, sleep disturbances, and academic decline. Several studies highlighted emotional investment and nighttime use as key mediators. Sleep disruption and academic interference were common outcomes across settings.</div></div><div><h3>Conclusion</h3><div>High levels of emotionally charged social media use among Arab children, adolescents, and young adults are associated with significant psychological and functional challenges, emphasizing the need for culturally tailored digital literacy and early screening. However, the predominance of cross-sectional designs across the included studies limits causal inference and underscores the necessity for future longitudinal and experimental research.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"115 ","pages":"Article 104793"},"PeriodicalIF":4.5,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145740553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prolonged intermittent theta burst stimulation as an alternative to standard rTMS: Real-world data from patients with non-psychotic major depression","authors":"Cheng-Ta Li ,&nbsp;Chih-Ming Cheng ,&nbsp;Hui-Ching Lin ,&nbsp;Jia-Shyun Jeng ,&nbsp;Tung-Ping Su ,&nbsp;Daniel M. Blumberger","doi":"10.1016/j.ajp.2025.104794","DOIUrl":"10.1016/j.ajp.2025.104794","url":null,"abstract":"<div><h3>Background</h3><div>While standard repetitive transcranial magnetic stimulation (rTMS) requires 20–30 sessions when treating patients with major depressive disorders (MDD), subthreshold prolonged intermittent theta burst stimulation (piTBS) may yield comparable effects in fewer visits—critical for self-paid treatment settings. piTBS has been reported to result in antidepressant response in as few as 10 sessions. However, most of them used small to moderate sample sizes.</div></div><div><h3>Methods</h3><div>We conducted a retrospective cohort study to examine the antidepressant effects of left prefrontal piTBS in clinical scenarios and to compare responses between piTBS and 10 Hz rTMS in patients who completed their treatments at distinct sessions in a large medical center. A total of 273 adult non-psychotic MDD patients were included in the analysis (120 piTBS and 153 rTMS). Patients received treatment in a private pay model on a daily basis and were encouraged to undergo at least 10–15 sessions, with the option of extending to 20 or more if a clinically meaningful response was not achieved.</div></div><div><h3>Results</h3><div>There were no significant differences in age, sex distribution, or baseline clinical variables between groups. Antidepressant effects were also comparable (piTBS vs. rTMS, responders= 49.2 % vs. 39.9 %; remitters= 34.2 % vs. 29.4 %). Notably, the piTBS group had a significantly lower stimulation intensity than the rTMS group (p &lt; 0.001) and required fewer total sessions (12.4 ± 3.3 vs. 14.5 ± 5.9)(p = 0.001). The piTBS group reported less local pain. Using piTBS treatment may yield a savings of US$750 to US$3000 per treatment course, which is a 25–66.7 % reduction in medical expenses.</div></div><div><h3>Conclusion</h3><div>In a real-world private pay model, subthreshold piTBS achieved comparable antidepressant effects to 10 Hz rTMS and resulted in cost and travel savings for patients.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"115 ","pages":"Article 104794"},"PeriodicalIF":4.5,"publicationDate":"2025-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145747250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Troubled teens and their fathers: The need to explore overlooked connections in mentalization literature","authors":"Arushee Wahi,&nbsp;Bangalore N. Roopesh,&nbsp;John Vijay Sagar Kommu","doi":"10.1016/j.ajp.2025.104792","DOIUrl":"10.1016/j.ajp.2025.104792","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"115 ","pages":"Article 104792"},"PeriodicalIF":4.5,"publicationDate":"2025-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145676163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}