Asian journal of psychiatry最新文献

英文中文

Psychometric properties and screening accuracy of the Chinese version of the Autism Symptom Dimensions Questionnaire 中文版自闭症症状维度问卷的心理测量特性及筛选准确性

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-25 DOI: 10.1016/j.ajp.2025.104790

Yichao Cheng , Jiaxin Shi , Yenan Wei , Jiahui Luo , Yongbo Shi , Zhimei Jiang

This study aims to explore the reliability and validity of the Chinese version of the Autism Symptom Dimensions Questionnaire (ASDQ) among children aged 3–8 years in China. It further investigates the optimal cutoff score and screening accuracy of this questionnaire for both primary and secondary screening of autism spectrum disorder (ASD). This study recruited a total of 575 Chinese children, including 106 children with ASD, 117 children with non-ASD neurodevelopmental disorders, and 352 typically developing children. The Chinese version of the ASDQ retained the original 9-factor model of the ASDQ, with 39 items in total. The reliability test results indicate that the Cronbach's α for internal consistency reliability was 0.944. In split-half reliability, the Cronbach's α for the first half was 0.878, while that for the second half was 0.916. The ICC coefficient for test-retest reliability was 0.917. Validity test results showed that the I-CVI for each item ranged from 0.857 to 1.000. In convergent validity, the AVE values for each factor ranged from 0.513 to 0.763; In discriminant validity, the square root of the AVE for each factor exceeded the maximum correlation coefficient with other factors; criterion-related validity analysis revealed that the absolute values of correlation coefficients ρ between the Chinese version of the ASDQ scores and criterion scales ranged from 0.615 to 0.889, all statistically significant. The results of the screening accuracy study showed that the optimal screening cutoff score for the primary screening was 2.49. For the secondary screening, the optimal cutoff score was 2.82. Research has found that the Chinese version of the ASDQ has good reliability and validity, demonstrating high screening accuracy in the detection of ASD. The Chinese version of ASDQ as an effective screening tool for ASD has high clinical application value and public health research value.

本研究旨在探讨中文版自闭症症状维度问卷（ASDQ）在中国3-8岁儿童中的信度和效度。进一步探讨该问卷对自闭症谱系障碍（ASD）初级和二级筛查的最佳分值和筛查准确性。本研究共招募了575名中国儿童，其中ASD儿童106名，非ASD神经发育障碍儿童117名，正常发育儿童352名。中文版ASDQ保留了原有的9因子模型，共有39个题项。信度检验结果表明，内部一致性信度的Cronbach’s α为0.944。在分半信度中，前半段的Cronbach’s α为0.878，后半段的Cronbach’s α为0.916。重测信度的ICC系数为0.917。效度检验结果显示，各条目的I-CVI在0.857 ~ 1.000之间。在收敛效度上，各因子的AVE值在0.513 ~ 0.763之间；在判别效度上，各因子AVE的平方根均超过与其他因子的最大相关系数；标准相关效度分析显示，中文版ASDQ评分与标准量表的相关系数ρ绝对值在0.615 ~ 0.889之间，均有统计学意义。筛选准确性研究结果表明，初筛的最佳筛选临界值为2.49分。对于二次筛查，最佳临界值为2.82。研究发现，中文版ASDQ具有良好的信度和效度，对ASD的检测具有较高的筛选准确性。ASDQ中文版作为一种有效的ASD筛查工具，具有较高的临床应用价值和公共卫生研究价值。

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引用次数: 0

Basophobia: A case report highlighting potential genetic vulnerability 恐Basophobia：一个突出潜在遗传脆弱性的案例报告

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-24 DOI: 10.1016/j.ajp.2025.104791

Jawahar Singh , Mahak Aggarwal , Pratiksha Bugalia , I.J. Srileka , Khushpreet Kaur

Basophobia, or space phobia, represents a rare form of specific phobia characterized by excessive fear of falling in open spaces without visible support. While familial aggregation has been documented in specific phobia generally, there are no previous reports documenting family clustering in basophobia specifically. We report the case of a 57-year-old woman who developed basophobia following a minor fall, with the notable finding of similar complaints in 30-year-old son. This case represents the first documented familial aggregation of basophobia and raises important questions about genetic vulnerability factors in this specific phobic subtype.

Basophobia或space phobia是一种罕见的特殊恐惧症，其特征是过度害怕在没有可见支撑的开放空间摔倒。虽然家族聚集性通常被记录在特定的恐惧症中，但没有先前的报告专门记录了basophobia的家庭聚集性。我们报告一例57岁的妇女，她在轻微跌倒后出现了basophobia，在30岁的儿子中也发现了类似的投诉。该病例代表了第一个记录在案的basophobia家族性聚集，并提出了关于这种特定恐惧症亚型的遗传易感性因素的重要问题。

引用次数: 0

Breathing and the brain: Pranayama, an ancient self-directed approach to neuromodulation 呼吸和大脑：调息，一种古老的自我导向的神经调节方法

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-22 DOI: 10.1016/j.ajp.2025.104788

Hemant Bhargav , Urvakhsh Meherwan Mehta , Ashish Kumar , Subha Subramanian , Matcheri S. Keshavan

This paper explores pranayama, the ancient yogic practice of breath control, as a promising natural method of neuromodulation. Pranayama aims to regulate the flow of prana (life force) to enhance mental clarity, emotional balance, and physiological resilience. We synthesize evidence from clinical, neuroimaging, and psychophysiological studies, illustrating how various pranayama techniques - including slow breathing, rapid breathing, and unilateral nostril breathing (UNB) -influence autonomic functions, brainwave patterns, and neuroendocrine responses. Mechanisms of pranayama such as vagus nerve stimulation, autonomic regulation, and hemispheric shifts in brain dominance are similar to contemporary neuromodulation approaches like transcranial magnetic stimulation (TMS), transcranial direct current stimulation (tDCS) and vagus nerve stimulation (VNS). However, pranayama offers an easily accessible, self-directed alternative to manage stress, enhance cognition, and promote emotion regulation. We identify significant knowledge gaps, including the need for well-powered, randomized-controlled studies to better understand the durability of effects, optimal protocols, and mechanisms of action. Pranayama represents a practical, low-risk, home-based neuromodulatory approach for preventative and adjunctive mental health care.

本文探讨调息，古老的瑜伽练习呼吸控制，作为一个有前途的自然方法的神经调节。调息旨在调节普拉那（生命力）的流动，以提高精神清晰度、情绪平衡和生理弹性。我们综合了来自临床、神经影像学和心理生理学研究的证据，说明了各种调息技巧——包括慢呼吸、快呼吸和单侧鼻孔呼吸（UNB）——如何影响自主神经功能、脑电波模式和神经内分泌反应。调息的机制，如迷走神经刺激、自主调节和大脑优势半球移位，与当代的神经调节方法如经颅磁刺激（TMS）、经颅直流电刺激（tDCS）和迷走神经刺激（VNS）相似。然而，调息法提供了一种易于实现的、自我导向的替代方法来管理压力、增强认知和促进情绪调节。我们发现了重大的知识缺口，包括需要强有力的随机对照研究，以更好地了解效果的持久性、最佳方案和作用机制。调息是一种实用的、低风险的、以家庭为基础的神经调节方法，用于预防和辅助精神卫生保健。

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引用次数: 0

Adolescent mental health in Indonesia: Lessons and reflections from China's experience 印尼青少年心理健康：中国经验的教训与反思

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-22 DOI: 10.1016/j.ajp.2025.104787

Meirinawati, Herananda Dewi Larasati Putri

引用次数: 0

Self-administered home digital cognitive enhancement system (DCES) enhances cognitive function in Chinese healthy elderly and its impact on cerebral cortex function: A randomized controlled trial study 自制家庭数字认知增强系统（DCES）增强中国健康老年人认知功能及其对大脑皮质功能的影响：一项随机对照试验研究。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-22 DOI: 10.1016/j.ajp.2025.104786

Xinrui Wang , Shaokun Zhao , Yingna Li , Huimei An , Ning Fan , Shuping Tan , Fude Yang

Objective

Cognitive function may decline with age, increasing the risk of dementia. Cognitive training can help to slow down this process. Digital Cognitive Enhancement System (DCES) is a novel home-based adaptive cognitive training system. We aim at evaluating and analyzing the efficacy of DCES in enhancing cognitive functions among the elderly and its neural mechanisms.

Methods

This 10-week study included 64 healthy elderly individuals, conducted as a single-blind, block-randomized controlled trial, registered at the China Clinical Trial Registry (ChiCTR2400091044). Participants were divided into the DCES group and the control group, with sessions occurring 5 days a week, each lasting 0.5 h, for a total of 10 weeks. Cognitive and brain function changes were assessed before and after the intervention, with results analyzed using linear-regression analysis and correlation coefficients calculated.

Results

After 10 weeks of intervention, the DCES group showed significant improvements in overall cognitive function, visuospatial function, memory and attention. DCES training significantly reduced fALFF values in the bilateral supramarginal gyrus (SMG). Its enhancement of immediate memory is closely linked to baseline activation levels in the left SMG.

Conclusion

The DCES training showed positive intervention effects, and changes in bilateral SMG activity may provide neurological support for cognitive ability enhancement.

目的：认知功能可能随着年龄的增长而下降，增加痴呆的风险。认知训练可以帮助减缓这个过程。数字认知增强系统（DCES）是一种新型的基于家庭的适应性认知训练系统。我们旨在评估和分析DCES对老年人认知功能的增强作用及其神经机制。方法：这项为期10周的研究纳入了64名健康老年人，作为一项单盲、块随机对照试验，在中国临床试验注册中心注册（ChiCTR2400091044）。参与者被分为DCES组和对照组，每周5天，每次持续0.5 h，共10周。评估干预前后认知和脑功能的变化，采用线性回归分析分析结果并计算相关系数。结果：干预10周后，DCES组在整体认知功能、视觉空间功能、记忆和注意力方面均有显著改善。DCES训练显著降低双侧边缘上回（SMG）的fALFF值。它对即时记忆的增强与左侧上皮层的基线激活水平密切相关。结论：DCES训练具有积极的干预作用，双侧侧颞叶颞叶活动的改变可能为认知能力增强提供神经学支持。

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引用次数: 0

“Bridging policy and lived realities: A critical commentary on Indonesia’s national mental health plan for adolescents” “衔接政策和生活现实：对印度尼西亚国家青少年心理健康计划的批评性评论”。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-22 DOI: 10.1016/j.ajp.2025.104789

Kadek Suhardita , Putu Ari Dharmayanti, I.Dewa Ayu Eka Purba Dharma Tari, Rikas Saputra, Erfan Ramadhani, Sri Datuti, Ulfah

引用次数: 0

Regional radiomics similarity networks reveal CSTC circuit abnormalities and clinical relevance in major depressive disorder 区域放射组学相似性网络揭示CSTC电路异常与重度抑郁症的临床相关性。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-20 DOI: 10.1016/j.ajp.2025.104785

Jingman Li , Shan Sun , Ling Yu , Jilei Chen , Jing Wu , Ruiyan Xie , Yuyun Huang , Liangliang Ping , Zhiyi You

The regional radiomics similarity network (R2SN) provides a structural network-level framework for investigating the neuropathology of major depressive disorder (MDD). In this study, we analyzed T1-weighted magnetic resonance imaging (MRI) data from 830 patients with MDD and 771 healthy controls (HCs) obtained from the REST-meta-MDD Project. Individual R2SNs were constructed using the Brainnetome atlas, and group differences in regional mean connectivity strength (RMCS) were assessed with general linear models (GLMs). We further applied partial least squares regression (PLSR) with leave-one-out cross-validation to evaluate the predictive ability of RMCS for Hamilton Depression Rating Scale-17 (HAMD-17) scores. Compared with HCs, patients with MDD exhibited significantly lower RMCS in cortico-striato-thalamo-cortical (CSTC) regions, including the middle and inferior frontal gyrus, precentral gyrus, superior temporal gyrus, postcentral gyrus, lateral occipital cortex, hippocampus, and caudate nucleus. Subgroup analyses revealed that patients with recurrent MDD showed reduced RMCS in the right dorsal caudate nucleus when compared with HCs, whereas first-episode drug-naïve (FEDN) patients did not. Moreover, the PLSR model demonstrated that RMCS significantly predicted HAMD-17 scores. Together, these findings highlight abnormalities in structural covariance networks in MDD, particularly within CSTC pathways, and underscore the potential of R2SN as a biomarker to guide individualized diagnosis and treatment planning in MDD.

区域放射组学相似性网络（R2SN）为研究重度抑郁症（MDD）的神经病理学提供了一个结构网络水平的框架。在这项研究中，我们分析了来自REST-meta-MDD项目的830名MDD患者和771名健康对照（hc）的t1加权磁共振成像（MRI）数据。使用脑组图谱构建个体R2SNs，并使用一般线性模型（GLMs）评估区域平均连接强度（RMCS）的组间差异。我们进一步应用偏最小二乘回归（PLSR）和留一交叉验证来评估RMCS对汉密尔顿抑郁评定量表-17 （HAMD-17）得分的预测能力。与正常人相比，MDD患者在皮质纹状体丘脑皮质（CSTC）区域的RMCS显著降低，包括额叶中下回、中央前回、颞上回、中央后回、枕侧皮质、海马和尾状核。亚组分析显示，与hcc患者相比，复发性MDD患者右侧尾状核背侧的RMCS减少，而首发drug-naïve （FEDN）患者则没有。此外，PLSR模型显示RMCS显著预测HAMD-17评分。总之，这些发现强调了MDD中结构协方差网络的异常，特别是在CSTC通路中，并强调了R2SN作为指导MDD个体化诊断和治疗计划的生物标志物的潜力。

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引用次数: 0

Broadening the evidence for hug-robot-mediated communication in autism spectrum disorder 拓宽自闭症谱系障碍中拥抱机器人介导的交流的证据。

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-15 DOI: 10.1016/j.ajp.2025.104775

Triyono Triyono, Rahmi Dwi Febriani, Fitria Kasih

引用次数: 0

Public stigma towards people with mental disorders in Singapore - Has anything changed? 新加坡公众对精神障碍患者的耻辱感——有什么改变吗？

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-14 DOI: 10.1016/j.ajp.2025.104771

Mythily Subramaniam , Shazana Shahwan , Edimansyah Abdin , Yoke Boon Tan , Savita Gunasekaran , Bernard Chin Wee Tan , Janhavi Ajit Vaingankar , Wei Jie Ong , Amit Arora , Weng Mooi Tan , Porsche Poh , Georg Schomerus , Siow Ann Chong

Background

The stigmatization of people with mental illness is a global phenomenon.

Aims

The current study aimed to (i) assess the extent of stigma and social distancing towards seven mental disorders, and track changes since the last mental health literacy study, and (ii) examine the socio-demographic and other correlates of stigma in the general population of Singapore, using a vignette approach.

Methods

We conducted interviews with 4195 Singapore Residents (aged 18–65) from September 2022 to February 2024, with a response rate of 62.3 %. Respondents were administered the Personal and Perceived scales of the Depression Stigma Scale and the Social Distance Scale to measure personal stigma and social distance, respectively. Multivariable linear regression analyses were conducted to examine associations.

Results

Mean stigma scores were significantly lower across all dimensions : ‘weak-not-sick’ (9.4 vs 10.2, p < 0.001), ‘dangerous/unpredictable’ (11.3 vs 11.6, p = 0.005), and ‘social distance’ (11.6 vs 12.0, p = 0.004) in the current study as compared to the previous study conducted in 2015. However, the magnitude of reduction varied substantially. The largest decline was observed in the ‘weak-not-sick’ dimension (-8.4 %), while ‘dangerous/unpredictable’ (-3.1 %) and ‘social distance’ (-2.8 %) showed smaller reductions.

Conclusions

The significant reduction in the ‘weak-not-sick’ dimension parallels large-scale anti-stigma initiatives in Singapore. However, the persistence of ‘social distance’ highlights a critical gap between improved public knowledge and intended behavior. Ongoing surveillance is necessary to determine whether these trends are sustained and to identify specific strategies that are effective in reducing behavioral stigma.

背景：对精神疾病患者的污名化是一种全球现象。目的：目前的研究旨在(i)评估对七种精神障碍的耻辱感和社会距离的程度，并跟踪自上次心理健康素养研究以来的变化，以及（ii）使用小文章方法检查新加坡普通人群中耻辱感的社会人口统计学和其他相关因素。方法：我们于2022年9月至2024年2月对4195名新加坡居民（18-65岁）进行了访谈，回复率为62.3 %。被调查者分别使用抑郁耻辱感量表的个人和感知量表和社会距离量表来测量个人耻辱感和社会距离。采用多变量线性回归分析来检验相关性。结果：在所有维度中，平均污名得分都显著降低：“弱-未病”（9.4 vs 10.2, p ）结论：“弱-未病”维度的显著降低与新加坡大规模的反污名举措相似。然而，“社会距离”的持续存在凸显了改善的公众知识和预期行为之间的关键差距。有必要进行持续监测，以确定这些趋势是否持续，并确定有效减少行为污名的具体战略。

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引用次数: 0

Methodological reflections on time-series approaches to suicide trends in South Korea 韩国自杀趋势时间序列方法的方法论反思

IF 4.5 4区医学 Q1 PSYCHIATRY

Asian journal of psychiatry

Pub Date : 2025-11-14 DOI: 10.1016/j.ajp.2025.104774

Marlon S. Frias

引用次数: 0

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全部化学•材料生命科学医学物理工程技术环境•农林材料科学地球科学法学管理学化学环境科学与生态学计算机科学教育学经济学农林科学人文科学生物学数学物理与天体物理心理学综合性期刊其他工业工程理学历史学农学文学信息工程

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