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Advancing psychotherapy in Malaysian psychiatric practice: The role of the psychotherapy chapter of the Malaysian Psychiatric Association 在马来西亚精神病实践中推进心理治疗:马来西亚精神病协会心理治疗分会的作用。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104877
Chong Seng Choi, Nik Ruzyanei Nik Jaafar
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引用次数: 0
PrecInNor: An Indo-Norway collaborative programme for precision psychiatry training PrecInNor:印度-挪威精确精神病学培训合作项目。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-10 DOI: 10.1016/j.ajp.2026.104852
Satish Suhas, Pravesh Parekh, Vanteemar S Sreeraj, Biju Viswanath, Srdjan Djurovic, Oleksandr Frei, Alexey A. Shadrin, Olav Bjerkehagen Smeland, Torill Ueland, Christine Lycke Brandt, Elisabeth Strand Vigtel, Reeteka Sud, Meera Purushottam, Ajay Kumar, M. Manjula, Anita Mahadevan, Ganesan Venkatasubramanian, Paulomi Matam Sudhir, John P. John, Ole A. Andreassen
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引用次数: 0
Climate change and mental health: A multinational study of climate-anxiety, coping, and psychosocial responses 气候变化与心理健康:气候焦虑、应对和心理社会反应的多国研究
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-20 DOI: 10.1016/j.ajp.2026.104859
Julio Torales , Iván Barrios , Antonio Ventriglio , João Mauricio Castaldelli-Maia , Myrna Lashley , Mike Campbell , Michael Liebrenz , Padmavati Ramachandran , Neil Krishan Aggarwal , Rowalt Alibudbud , Egor Chumakov , Joana Corrêa de Magalhães Narvaez , Afzal Javed , Dinesh Bhugra , Albert Persaud , on behalf of the World Psychiatric Association Special Interest Group on Geopsychiatry

Background

Climate change is an increasingly important determinant of global mental health, affecting emotional, cognitive, behavioral, and social functioning. The emergence of climate-anxiety and the unequal distribution of environmental risks highlight the need for cross-cultural evidence to inform equitable adaptation strategies.

Aim

To examine the psychological and functional impacts of climate change across diverse populations, focusing on climate-anxiety, emotional responses, coping strategies, and perceived psychosocial support within a geopsychiatry framework.

Methods

A multinational cross-sectional survey was conducted among 388 adults from 44 countries using the Hogg Climate Anxiety Scale (HCAS) and additional items on climate-related experiences, functional disruption, coping strategies, and access to essential resources. Data were analyzed using descriptive statistics, non-parametric tests, multiple linear regression, and thematic analysis of open-ended responses.

Results

Overall, 83.5 % of participants reported exposure to at least one extreme climate event in the past five years, most commonly heatwaves, floods, and severe storms. Climate anxiety differed by gender in affective symptoms, rumination, and personal impact anxiety (Kruskal–Wallis, p ≤ .007). Participants exposed to extreme events reported higher affective (p = .017), behavioral (p = .001), and personal impact anxiety (p = .045). The regression model explained 25 % of the variance in total HCAS scores (R² = 0.25, p < .001), with climate-related functional disruption as the strongest predictor.

Conclusions

Climate change is associated with substantial emotional and functional burden, particularly among vulnerable groups. Findings support integrating mental health screening and brief psychosocial interventions into climate adaptation policies, primary care, and community-based resilience programs.
气候变化是全球心理健康日益重要的决定因素,影响着情绪、认知、行为和社会功能。气候焦虑的出现和环境风险的不平等分布突出表明需要跨文化证据来为公平的适应战略提供信息。目的研究气候变化对不同人群的心理和功能影响,重点关注气候焦虑、情绪反应、应对策略和在地精神病学框架内感知的社会心理支持。方法采用霍格气候焦虑量表(HCAS)对来自44个国家的388名成年人进行了一项跨国横断面调查,并对气候相关经历、功能破坏、应对策略和基本资源的获取等附加项目进行了调查。数据分析采用描述性统计、非参数检验、多元线性回归和开放式回答的专题分析。结果总体而言,83.5% %的参与者报告在过去五年中至少经历过一次极端气候事件,最常见的是热浪、洪水和严重风暴。气候焦虑在情感症状、反刍和个人影响焦虑方面存在性别差异(Kruskal-Wallis, p ≤ .007)。暴露于极端事件的参与者报告了更高的情感(p = )。017),行为(p = 。001)和个人影响焦虑(p = .045)。回归模型解释了总HCAS评分方差的25% % (R²= 0.25,p <; )。001),与气候相关的功能破坏是最强的预测因子。结论气候变化与严重的情感和功能负担有关,特别是在弱势群体中。研究结果支持将心理健康筛查和简短的社会心理干预纳入气候适应政策、初级保健和基于社区的复原力规划。
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引用次数: 0
Perspectives on psychotherapy in Southeast Asia: Insights from psychiatrists and trainees (Part II: Barriers to access and future directions) 东南亚心理治疗的观点:来自精神科医生和学员的见解(第二部分:获取障碍和未来方向)
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-25 DOI: 10.1016/j.ajp.2026.104873
Warut Aunjitsakul , Kanthee Anantapong , Nisan Werachattawan , Kreuwan Jongbovonwiwat , Rasmon Kalayasiri , Daruj Aniwattanapong , Poom Chompoosri , Andre Teck Sng Tay , Samuel Eng Teck Cheng , Sanjiv Sasidharan Nair , David Choon Liang Teo , Petrin Redayani Lukman , Sylvia Detri Elvira , Alfi Fajar Almasyhur , Nik Ruzyanei Nik Jaafar , Farah Nabila binti Abd Majid , Jiann Lin Loo , Nuur Asyikin binti Mohd Shukor , Eric Bui , Thi Tuong Vi Vu , César A. Alfonso

Background

Psychotherapy's integration into Southeast Asia (SEA) clinical practice is limited despite its recognized effectiveness. This study examined psychiatrists’ and psychiatry trainees’ perspectives on barriers to accessing psychotherapy, expectations for its future delivery, and attitudes toward digital mental health.

Methods

A cross-national survey was conducted between March and August 2024 among 253 psychiatrists and psychiatry trainees from Indonesia (n = 121), Malaysia (n = 39), Singapore (n = 6), Thailand (n = 74), and Vietnam (n = 13). The questionnaire explored perspectives on delivering psychotherapy including barriers, provider roles, therapy formats, and digital delivery. Data were analyzed descriptively and comparatively.

Results

Key barriers to delivering psychotherapy included time constraints, cost concerns, systemic limitations, and insufficient psychotherapy skills, respectively. Regarding preferences for psychotherapy providers, trainees rated psychiatrists as most suitable, while psychiatrists preferred psychologists. Crisis intervention and individual therapy were the top priorities for training. Although videoconferencing and mobile apps were favored for future delivery, concerns about clinical effectiveness and system-level limitations hindered wider acceptance of digital psychotherapy.

Conclusion

A major barrier was that psychotherapy is too time-consuming, and a lack of skills was a significant challenge for healthcare professionals. Both psychiatrists and trainees agreed that training should prioritize crisis intervention and individual therapy. For internet-based psychotherapy, the primary challenge was concern over its low clinical effectiveness, as many felt face-to-face interaction was necessary. The findings highlight the need for enhanced psychotherapy training, systemic support, and digital infrastructure to improve psychotherapy accessibility in SEA. These insights can inform the development of targeted interventions and policies to promote the effective integration of psychotherapy into mental health services in the region.
背景心理治疗融入东南亚(SEA)临床实践,尽管其公认的有效性是有限的。这项研究调查了精神科医生和精神病学学员对获得心理治疗障碍的看法,对其未来交付的期望,以及对数字心理健康的态度。MethodsA跨国调查在253年3月和2024年8月在精神病医生和精神病学学员从印度尼西亚(n = 121),马来西亚(n = 39)、新加坡(n = 6),泰国(n = 74)和越南(n = 13)。问卷调查探讨了提供心理治疗的观点,包括障碍、提供者角色、治疗形式和数字化交付。对数据进行描述性和对比性分析。结果提供心理治疗的主要障碍分别为时间限制、费用问题、系统限制和心理治疗技能不足。关于心理治疗提供者的偏好,受训人员认为精神科医生是最合适的,而精神科医生更喜欢心理学家。危机干预和个体治疗是培训的重点。尽管视频会议和移动应用程序在未来的传播中受到青睐,但对临床有效性和系统层面限制的担忧阻碍了数字心理治疗的广泛接受。结论心理治疗的主要障碍是心理治疗耗时长,缺乏技能是医护人员面临的重大挑战。精神科医生和学员都认为培训应该优先考虑危机干预和个体治疗。对于基于网络的心理治疗,主要的挑战是对其临床有效性的担忧,因为许多人认为面对面的互动是必要的。研究结果强调需要加强心理治疗培训、系统支持和数字基础设施,以改善东南亚地区心理治疗的可及性。这些见解可为制定有针对性的干预措施和政策提供信息,以促进将心理治疗有效地纳入该区域的精神卫生服务。
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引用次数: 0
Ten sessions, faster response, or faster exit? Clarifying “Speed” and cost claims in piTBS vs 10-Hz rTMS 十个会话,更快的响应,还是更快的退出?澄清piTBS和10hz rTMS的“速度”和成本要求。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104881
Xiaowei Zhang
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引用次数: 0
Impaired task-switching in major depressive disorder: A time-frequency analysis of non-emotional and emotional stimuli 重度抑郁症的任务转换受损:非情绪和情绪刺激的时频分析。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.ajp.2026.104879
Kaili Zheng , Wanrong Peng , Zhaoxia Liu , Xiaoshuang Gu , Meiqian Tang , Weijun Situ , Jinyao Yi

Background

Major depressive disorder (MDD) is characterized by significant impairments in cognitive functions, including task-switching dysfunction. This study investigates the differences in switching impairments between non-emotional and emotional switching tasks in MDD patients and explores the underlying neuropsychological mechanisms.

Methods

48 MDD patients and 52 healthy controls (HCs) were recruited. Behavioral and electroencephalogram data were recorded while participants performed non-emotional and emotional task-switching paradigms. Event-related potentials (ERPs: P2, N2, P3 difference waves) and event-related spectral perturbations (ERSPs: theta, alpha, beta band power) were analyzed to assess group differences.

Results

In the magnitude task, MDD group displayed reduced occipital Pd2 amplitude (p < 0.001, η2p=0.20), increased frontal/central Pd3 amplitudes (p < 0.001, η2p=0.10), and larger alpha power differences (p < 0.05, η2p= 0.04). In the gender task, MDD group had increased occipital Pd2 amplitude (p < 0.05, η2p=0.04) and larger alpha power differences in the P3 time window (p < 0.01, η2p=0.03). In the emotion task, MDD group showed prolonged Pd2 latency (p < 0.05, η2p=0.04), reduced Pd3 amplitude (p < 0.05, η2p=0.10), smaller theta power differences (p = 0.05, η2p=0.03), and larger beta power differences (p < 0.05, η2p=0.04).

Conclusion

MDD patients exhibit a dissociable pattern of task-switching deficits across non-emotional and emotional task-switching scenarios, characterized by distinct abnormalities across early visual processing, conflict monitoring, cognitive resource allocation, and multi-stage emotional processing. This study reveals novel electrophysiological mechanisms underlying cognitive inflexibility in MDD.
背景:重度抑郁症(MDD)的特征是认知功能的显著损伤,包括任务转换功能障碍。本研究探讨重度抑郁症患者非情绪性和情绪性转换任务的转换障碍差异,并探讨其潜在的神经心理学机制。方法:选取48例重度抑郁症患者和52例健康对照。当参与者进行非情绪和情绪任务转换范式时,记录他们的行为和脑电图数据。分析事件相关电位(ERPs: P2、N2、P3差波)和事件相关谱扰动(ERSPs: θ、α、β波段功率)来评估组间差异。结果:在幅度任务中,MDD组枕部Pd2幅值降低(p 2p=0.20),额部/中央Pd3幅值增加(p 2p=0.10), alpha功率差异较大(p 2p= 0.04)。在性别任务中,MDD组枕部Pd2振幅增加(p 2p=0.04), P3时间窗α功率差异更大(p 2p=0.03)。在情绪任务中,MDD组Pd2潜伏期延长(p 2p=0.04), Pd3振幅减小(p 2p=0.10), θ功率差异较小(p = 0.05,η2p=0.03), β功率差异较大(p 2p=0.04)。结论:MDD患者在非情绪性和情绪性任务转换情景中表现出可分离的任务转换缺陷模式,其特征是在早期视觉加工、冲突监测、认知资源分配和多阶段情绪加工中表现出明显的异常。本研究揭示了重度抑郁症认知不灵活性的新电生理机制。
{"title":"Impaired task-switching in major depressive disorder: A time-frequency analysis of non-emotional and emotional stimuli","authors":"Kaili Zheng ,&nbsp;Wanrong Peng ,&nbsp;Zhaoxia Liu ,&nbsp;Xiaoshuang Gu ,&nbsp;Meiqian Tang ,&nbsp;Weijun Situ ,&nbsp;Jinyao Yi","doi":"10.1016/j.ajp.2026.104879","DOIUrl":"10.1016/j.ajp.2026.104879","url":null,"abstract":"<div><h3>Background</h3><div>Major depressive disorder (MDD) is characterized by significant impairments in cognitive functions, including task-switching dysfunction. This study investigates the differences in switching impairments between non-emotional and emotional switching tasks in MDD patients and explores the underlying neuropsychological mechanisms.</div></div><div><h3>Methods</h3><div>48 MDD patients and 52 healthy controls (HCs) were recruited. Behavioral and electroencephalogram data were recorded while participants performed non-emotional and emotional task-switching paradigms. Event-related potentials (ERPs: P2, N2, P3 difference waves) and event-related spectral perturbations (ERSPs: theta, alpha, beta band power) were analyzed to assess group differences.</div></div><div><h3>Results</h3><div>In the magnitude task, MDD group displayed reduced occipital Pd2 amplitude (<em>p</em> &lt; 0.001, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.20), increased frontal/central Pd3 amplitudes (<em>p</em> &lt; 0.001, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.10), and larger alpha power differences (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>= 0.04). In the gender task, MDD group had increased occipital Pd2 amplitude (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04) and larger al<em>p</em>ha power differences in the P3 time window (<em>p</em> &lt; 0.01, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.03). In the emotion task, MDD group showed prolonged Pd2 latency (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04), reduced Pd3 amplitude (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.10), smaller theta power differences (<em>p</em> = 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.03), and larger beta power differences (<em>p</em> &lt; 0.05, <em>η</em><sup><em>2</em></sup><sub><em>p</em></sub>=0.04).</div></div><div><h3>Conclusion</h3><div>MDD patients exhibit a dissociable pattern of task-switching deficits across non-emotional and emotional task-switching scenarios, characterized by distinct abnormalities across early visual processing, conflict monitoring, cognitive resource allocation, and multi-stage emotional processing. This study reveals novel electrophysiological mechanisms underlying cognitive inflexibility in MDD.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104879"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effectiveness of technology-based intervention programs in the prevention of child abuse: A systematic review and meta-analysis study 基于技术的干预方案在预防儿童虐待中的有效性:一项系统回顾和荟萃分析研究。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-02-07 DOI: 10.1016/j.ajp.2026.104887
Edanur Tar Bolacali , Gökçe Demir , Bahar Aksoy , Sevda Uzun
This study was conducted with the aim of revealing the effectiveness of technology-based intervention programs in the prevention of child abuse. For this systematic review and meta-analysis study, researches were obtained by searching PubMed, Web of Science, Scopus, Google Scholar and National Thesis Center of the Council of Higher Education databases without any year limitation. After the review, 18 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. In this systematic review and meta-analysis, it was found that technology-based intervention programs were effective in preventing child abuse in educators and caregivers (SMD: 0.673; 95% CI: 0.500–1.243; Z = 4.594, p = 0.00, (I2 = 77.6%). In addition, technology-based intervention programs were found to be effective in preventing child abuse in children SMD: 0.255 95% CI: −0.059 to 0.570; Z = 1.589, p = 0.112, (I2 = 59.6%) and parents (SMD: 0.194 95% CI: −0.584 to 0.973; Z = 0.490, p = 0.624, (I2= 97.6%). This study showed that technology-based intervention programs can play a beneficial and important role on individuals in the prevention of child abuse.
本研究旨在揭示以科技为基础的干预计划在预防虐待儿童方面的有效性。本系统综述和荟萃分析研究通过检索PubMed、Web of Science、Scopus、谷歌Scholar和美国高等教育委员会国家论文中心数据库获得研究结果,不受年份限制。回顾后,18项研究被纳入研究。采用元分析和叙述方法对数据进行综合。在本系统回顾和荟萃分析中,我们发现基于技术的干预方案在预防教育工作者和照顾者虐待儿童方面是有效的(SMD: 0.673; 95% CI: 0.500-1.243; Z = 4.594,p = 0.00,(I2 = 77.6%)。此外,以技术为基础的干预方案被发现在预防儿童SMD中虐待儿童方面是有效的:0.255 95% CI: -0.059至0.570;Z = 1.589,p = 0.112,(I2 = 59.6%)和家长(SMD: 0.194 - 95%置信区间:-0.584 - 0.973;Z = 0.490,p = 0.624,(I2 = 97.6%)。这项研究表明,以技术为基础的干预计划可以在预防儿童虐待方面对个人发挥有益和重要的作用。
{"title":"The effectiveness of technology-based intervention programs in the prevention of child abuse: A systematic review and meta-analysis study","authors":"Edanur Tar Bolacali ,&nbsp;Gökçe Demir ,&nbsp;Bahar Aksoy ,&nbsp;Sevda Uzun","doi":"10.1016/j.ajp.2026.104887","DOIUrl":"10.1016/j.ajp.2026.104887","url":null,"abstract":"<div><div>This study was conducted with the aim of revealing the effectiveness of technology-based intervention programs in the prevention of child abuse. For this systematic review and meta-analysis study, researches were obtained by searching PubMed, Web of Science, Scopus, Google Scholar and National Thesis Center of the Council of Higher Education databases without any year limitation. After the review, 18 studies were included in the study. The data were synthesized by meta-analysis and narrative methods. In this systematic review and meta-analysis, it was found that technology-based intervention programs were effective in preventing child abuse in educators and caregivers (SMD: 0.673; 95% CI: 0.500–1.243; Z = 4.594, p = 0.00, (I<sup>2</sup> = 77.6%). In addition, technology-based intervention programs were found to be effective in preventing child abuse in children SMD: 0.255 95% CI: −0.059 to 0.570; Z = 1.589, p = 0.112, (I<sup>2</sup> = 59.6%) and parents (SMD: 0.194 95% CI: −0.584 to 0.973; Z = 0.490, p = 0.624, (I<sup>2</sup>= 97.6%). This study showed that technology-based intervention programs can play a beneficial and important role on individuals in the prevention of child abuse.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104887"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146163933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The clue on the bleeding face: Unpacking MiTES (midface toddler excoriation syndrome) through genetics and behaviour 流血的脸上的线索:通过遗传和行为来去除螨虫(脸中部幼儿擦伤综合征)
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.ajp.2026.104848
Srivastava Akash , Bhatnagar Priyanka, P.K. Pardal
{"title":"The clue on the bleeding face: Unpacking MiTES (midface toddler excoriation syndrome) through genetics and behaviour","authors":"Srivastava Akash ,&nbsp;Bhatnagar Priyanka,&nbsp;P.K. Pardal","doi":"10.1016/j.ajp.2026.104848","DOIUrl":"10.1016/j.ajp.2026.104848","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104848"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145975419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Pisa syndrome in a 4-year-old child with autism spectrum disorder: The youngest reported case of risperidone-induced extrapyramidal reaction 急性比萨综合征的4岁儿童自闭症谱系障碍:最年轻的利培酮诱导锥体外反应的报告病例
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-07 DOI: 10.1016/j.ajp.2026.104838
Himanshu Garg, Abhishek Pandey, Neha Anushree, Shobit Garg , Karthik Ram Mohan

Background

Pisa syndrome is a rare extrapyramidal disorder characterized by sustained lateral flexion of the trunk, typically associated with antipsychotic medications. Though well-described in adult populations, its occurrence in children is exceedingly rare, with no previously reported cases in children under 12 years of age for drug-induced etiology.

Clinical description

We report the case of a 4-year-old boy with autism spectrum disorder (ASD), receiving risperidone (0.5 mL BID) for behavioural issues, on continued behavioural therapy, who developed acute onset painful lateral flexion of the trunk—clinically consistent with Pisa syndrome.

Management & outcome

He was promptly treated with intravenous pheniramine maleate, with immediate resolution of symptoms. Risperidone was discontinued, and no recurrence was noted on follow-up. Causality assessment using the Pediatric Naranjo Adverse Drug Reaction Probability Scale yielded a score of 7, indicating a probable adverse drug reaction to risperidone.

Conclusion

This case underscores the importance of early recognition of rare extrapyramidal side effects such as Pisa syndrome in children on atypical antipsychotics. Clinicians should maintain a high index of suspicion, even in very young children, and be aware of effective management strategies.
背景:pisa综合征是一种罕见的锥体外系疾病,以躯干持续侧屈为特征,通常与抗精神病药物有关。虽然在成人人群中有很好的描述,但在儿童中的发生极为罕见,以前没有12岁以下儿童因药物引起的病因的病例报道。临床描述:我们报告了一名患有自闭症谱系障碍(ASD)的4岁男孩,接受利培酮(0.5 mL BID)治疗行为问题,并继续接受行为治疗,他出现了急性发作的躯干疼痛侧屈-临床表现与Pisa综合征一致。处理和结果患者立即静脉注射马来酸苯那敏治疗,症状立即缓解。利培酮停用,随访未见复发。使用儿童纳兰霍药物不良反应概率量表进行因果关系评估,得分为7分,表明可能对利培酮产生不良反应。结论本病例强调了早期识别非典型抗精神病药物治疗中罕见的锥体外系副作用如比萨综合征的重要性。临床医生应保持高度的怀疑指数,即使在非常年幼的儿童,并意识到有效的管理策略。
{"title":"Acute Pisa syndrome in a 4-year-old child with autism spectrum disorder: The youngest reported case of risperidone-induced extrapyramidal reaction","authors":"Himanshu Garg,&nbsp;Abhishek Pandey,&nbsp;Neha Anushree,&nbsp;Shobit Garg ,&nbsp;Karthik Ram Mohan","doi":"10.1016/j.ajp.2026.104838","DOIUrl":"10.1016/j.ajp.2026.104838","url":null,"abstract":"<div><h3>Background</h3><div>Pisa syndrome is a rare extrapyramidal disorder characterized by sustained lateral flexion of the trunk, typically associated with antipsychotic medications. Though well-described in adult populations, its occurrence in children is exceedingly rare, with no previously reported cases in children under 12 years of age for drug-induced etiology.</div></div><div><h3>Clinical description</h3><div>We report the case of a 4-year-old boy with autism spectrum disorder (ASD), receiving risperidone (0.5 mL BID) for behavioural issues, on continued behavioural therapy, who developed acute onset painful lateral flexion of the trunk—clinically consistent with Pisa syndrome.</div></div><div><h3>Management &amp; outcome</h3><div>He was promptly treated with intravenous pheniramine maleate, with immediate resolution of symptoms. Risperidone was discontinued, and no recurrence was noted on follow-up. Causality assessment using the Pediatric Naranjo Adverse Drug Reaction Probability Scale yielded a score of 7, indicating a probable adverse drug reaction to risperidone.</div></div><div><h3>Conclusion</h3><div>This case underscores the importance of early recognition of rare extrapyramidal side effects such as Pisa syndrome in children on atypical antipsychotics. Clinicians should maintain a high index of suspicion, even in very young children, and be aware of effective management strategies.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104838"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145923862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Is loneliness related to greater use of DeepSeek as an AI companion? A study from China 孤独感是否与深度搜索作为人工智能伴侣的更多使用有关?一项来自中国的研究。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-03-01 Epub Date: 2026-01-08 DOI: 10.1016/j.ajp.2026.104845
Christian Montag, Wang Yao, Zhiying Zhao, Jon D. Elhai, Shujun Liu, Haibo Yang
{"title":"Is loneliness related to greater use of DeepSeek as an AI companion? A study from China","authors":"Christian Montag,&nbsp;Wang Yao,&nbsp;Zhiying Zhao,&nbsp;Jon D. Elhai,&nbsp;Shujun Liu,&nbsp;Haibo Yang","doi":"10.1016/j.ajp.2026.104845","DOIUrl":"10.1016/j.ajp.2026.104845","url":null,"abstract":"","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"117 ","pages":"Article 104845"},"PeriodicalIF":4.5,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146008564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Asian journal of psychiatry
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