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Integrating pharmaco-multiomics and AI for precision perinatal psychiatry: A call for dynamic dosing 整合药物-多组学和人工智能用于精确围产期精神病学:呼吁动态给药
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-06 DOI: 10.1016/j.ajp.2026.104834
Mohamed A. Ismail
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引用次数: 0
Psychobiotics as adjuncts in depression management: Mechanistic insights and clinical perspectives 精神生物制剂在抑郁症治疗中的辅助作用:机制见解和临床观点
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-06 DOI: 10.1016/j.ajp.2026.104840
Sabbu Rahul, Radhakrishnan Rahul, Vaishnavi Gudupalli
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引用次数: 0
Multi-view ensemble learning for EEG-based detection of Obsessive–Compulsive Disorder 基于脑电图的强迫症检测的多视图集成学习。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-06 DOI: 10.1016/j.ajp.2025.104827
Aditya Kumar , Ravi Patel , Niharika Koch , Jainath Yadav
Psychiatric disorders pose a critical challenge in modern healthcare due to their high prevalence, complex symptomatology, and reliance on subjective diagnostic procedures. Obsessive–Compulsive Disorder (OCD), in particular, is a chronic and debilitating condition that significantly impairs daily functioning, yet remains difficult to diagnose accurately and objectively. To address this challenge, we propose a novel frequency-aware multi-view ensemble learning framework for EEG-based OCD classification. The method systematically partitions EEG features into frequency-specific views (delta, theta, alpha, beta, and gamma), thereby capturing complementary neural dynamics associated with different cognitive and affective processes. For each frequency view, multiple base classifiers are trained, and their probabilistic outputs are integrated through a Particle Swarm Optimization (PSO)-based weight optimization strategy. This ensures that more informative frequency bands and classifiers contribute proportionally to the final prediction. Comprehensive experiments conducted on clinical EEG datasets demonstrate that the proposed model achieves superior performance, with an average accuracy of 90.1%, precision of 90.6%, recall of 90.1%, and F1-score of 89.7%, significantly outperforming state-of-the-art baselines such as SVM (70.2% accuracy) and Random Forest (68.7% accuracy). The results establish the clinical potential of this framework as a robust, non-invasive, and scalable computational tool to complement traditional psychiatric assessment and improve diagnostic precision in OCD recognition.
精神疾病构成了一个关键的挑战,在现代医疗保健,由于其高患病率,复杂的症状,并依赖于主观诊断程序。尤其是强迫症(OCD),它是一种慢性衰弱性疾病,严重损害日常功能,但仍然难以准确客观地诊断。为了解决这一挑战,我们提出了一种新的频率感知多视图集成学习框架,用于基于脑电图的强迫症分类。该方法系统地将EEG特征划分为特定频率的视图(delta, theta, alpha, beta和gamma),从而捕获与不同认知和情感过程相关的互补神经动力学。对于每个频率视图,训练多个基分类器,并通过基于粒子群优化(PSO)的权重优化策略整合它们的概率输出。这确保了更多信息频带和分类器对最终预测的贡献成比例。在临床脑电图数据集上进行的综合实验表明,该模型的平均准确率为90.1%,精密度为90.6%,召回率为90.1%,f1得分为89.7%,显著优于目前最先进的SVM(准确率为70.2%)和Random Forest(准确率为68.7%)等基线。结果确立了该框架作为一种强大的、无创的、可扩展的计算工具的临床潜力,以补充传统的精神病学评估并提高强迫症识别的诊断精度。
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引用次数: 0
Gender paradox in suicidal behavior: Possible reasons and implications for suicide prevention in the South-East Asian region 自杀行为中的性别矛盾:东南亚地区自杀预防的可能原因和影响
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-06 DOI: 10.1016/j.ajp.2026.104833
Sujita Kumar Kar, Vikas Menon
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引用次数: 0
The Asian Journal of Psychiatry: An end of year review 2025 《亚洲精神病学杂志》:2025年年终回顾
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-05 DOI: 10.1016/j.ajp.2026.104835
Rajiv Tandon
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引用次数: 0
Functional neurological symptoms and their correlates across four Asian samples: Should they be classified as a dissociative disorder? 四个亚洲样本的功能性神经症状及其相关性:它们应该被归类为分离性障碍吗?
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-04 DOI: 10.1016/j.ajp.2026.104831
Tsz Lam Chan , Valerie Yan Tung Siu , Shan-yan Huang , Amos En Zhe Lian , Marc Eric S. Reyes , Görkem Derin , Aslı Dila Akiş , Audrey Zatopek , Stanley Kam Ki Lam , Peejay D. Bengwasan , Hong Wang Fung
Whether functional neurological symptom disorder should be classified as a dissociative disorder remains a subject of debate. This multi-site, cross-cultural study investigated functional neurological symptoms and psychoform dissociation among college students in the Philippines (N = 219), Turkey (N = 160), Malaysia (N = 240), and Taiwan (N = 766). Across the four samples, between 50.0 % and 74.2 % of participants with functional neurological symptoms exhibited co-occurring psychoform dissociative symptoms. Controlling for confounding variables (e.g., age, gender, childhood adversities, and symptoms of depression, anxiety, and complex PTSD), psychoform dissociative symptoms emerged as the strongest and most robust correlate of functional neurological symptoms in three out of four samples (Philippines: β = .502, Turkey: β = .665, Malaysia: β = .541). Psychoform dissociative symptoms were also significantly associated with functional neurological symptoms in the Taiwan sample (β = .122), although not the strongest predictor. The results that were replicated across four culturally different samples support classifying functional neurological symptom disorder as possibly dissociative in nature in future ICD and DSM. Individuals who present with functional neurological symptoms should be screened for dissociative disorders.
功能性神经症状障碍是否应该归类为分离性障碍仍然是一个有争议的话题。这项多地点、跨文化研究调查了菲律宾(N = 219)、土耳其(N = 160)、马来西亚(N = 240)和台湾(N = 766)大学生的功能性神经症状和精神形态分离。在四个样本中,50.0% %至74.2 %的具有功能性神经症状的参与者表现出同时发生的精神形态分离症状。在控制混杂变量(例如,年龄、性别、童年逆境以及抑郁、焦虑和复杂创伤后应激障碍的症状)后,在四个样本中有三个样本(菲律宾:β = .502,土耳其:β = .665,马来西亚:β = .541)中,精神形态解离症状成为功能神经症状最强烈和最有力的相关性。在台湾样本中,精神形态解离性症状也与功能性神经症状显著相关(β = 0.122),尽管不是最强的预测因子。在四个文化不同的样本中重复的结果支持在未来的ICD和DSM中将功能性神经症状障碍分类为可能的解离性。出现功能性神经症状的个体应进行分离性障碍筛查。
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引用次数: 0
The effect of spatial and intensity level augmentation of structural magnetic resonance images on autism diagnosis model 结构磁共振图像空间和强度增强对自闭症诊断模型的影响。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-04 DOI: 10.1016/j.ajp.2026.104830
D. Swainson Sujana, Peter Augustin D
In deep learning, the robustness and generalizability of models significantly depend on diverse and heterogeneous training data. Acquiring such an extensive dataset is challenging in fields like disorder prediction due to data scarcity, which can be attributed to factors such as privacy concerns, limited patient population, or inadequate facilities. Data augmentation can be an ideal solution to this problem, particularly in the field of disorder prediction, like autism, using medical imaging. Data augmentation can expand and balance datasets by generating high-quality and varied data, thereby improving the generalizability of deep learning models. This study proposed two types of augmentation methods: 1. Spatial level 2. Intensity level augmentation techniques. Eight different levels of augmentations were experimented with across these categories. This study found that the combination of spatial and intensity level augmentations enhanced the model’s generalizability and robustness, achieving an AUC value of 0.7433. Additionally, it was observed that the Left to Right flip method, under spatial augmentation, diminished the model’s performance, whereas random noise injection, under intensity level augmentation, improved prediction accuracy.
在深度学习中,模型的鲁棒性和泛化性在很大程度上取决于训练数据的多样性和异质性。由于数据稀缺,获取如此广泛的数据集在疾病预测等领域具有挑战性,这可归因于隐私问题、患者人数有限或设施不足等因素。数据增强可以是解决这个问题的理想方案,特别是在疾病预测领域,如自闭症,使用医学成像。数据增强可以通过生成高质量和多样化的数据来扩展和平衡数据集,从而提高深度学习模型的泛化能力。本研究提出了两种增强方法:1。空间等级2。强度水平增强技术。在这些类别中实验了八种不同程度的增强。研究发现,空间和强度叠加增强了模型的泛化性和鲁棒性,AUC值为0.7433。此外,在空间增强下,从左到右翻转方法降低了模型的性能,而在强度级增强下,随机噪声注入提高了预测精度。
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引用次数: 0
Strengthening maternal mental health through Collaborative Care Model: A scalable opportunity for LMICs 通过协作护理模式加强孕产妇心理健康:中低收入国家的可扩展机会。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-04 DOI: 10.1016/j.ajp.2026.104832
Zahid Hyder Wadani
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引用次数: 0
National-, institutional-, and individual-level determinants of psychiatric research excellence: Analysis of Stanford-Elsevier lists of the top 2 % scholars worldwide (2017–2023) 精神病学研究卓越性的国家、机构和个人层面的决定因素:斯坦福-爱思唯尔全球排名前2 %学者名单分析(2017-2023)
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-02 DOI: 10.1016/j.ajp.2025.104826
Abanoub Riad , Muhammad Alkasaby , Nisarat Changchroenkul , Michal Koščík

Background

Research excellence is increasingly used as a benchmark for academic evaluation in medical sciences, including psychiatry. However, bibliometric analyses often prioritize productivity over quality. This study examined national, institutional, and individual determinants of psychiatric research excellence using a multi-level ecological framework.

Methods

We analyzed the Stanford–Elsevier Lists of the top 2 % scholars (2017–2023), incorporating 51 independent variables. These included: (a) national determinants grouped into five domains (mental healthcare, gender equity, socioeconomic development, budgetary policies, and disease burden), (b) institutional factors derived from global and discipline-specific rankings, and (c) individual factors of gender and academic age. The primary outcome was the number of excellent psychiatric scholars (EPS), with secondary indicators including citation counts, modified H-index, composite score, and self-citation share.

Results

Psychiatric research excellence was concentrated in high-income, English-speaking countries, with significant institutional elitism. A small number of institutions hosted a disproportionate share of EPS. Gender disparities persisted, with female representation negatively associated with national gender gaps in employment and education, but positively linked to government spending on education. Academic age positively correlated with citation-based performance metrics. Multivariable models confirmed the explanatory roles of gender, academic age, official language, gender equity, and human development.

Conclusion

Psychiatric research excellence reflects systemic advantages related to income, language, institutional prestige, and gender equity. Equitable funding, support for emerging research environments, and expanded international collaboration are essential to fostering broader participation in high-impact psychiatric research.
研究卓越性越来越多地被用作医学科学(包括精神病学)学术评估的基准。然而,文献计量学分析往往优先考虑生产力而不是质量。本研究使用多层次生态框架考察了精神病学研究卓越的国家、机构和个人决定因素。方法对2017-2023年斯坦福-爱思唯尔排名 %前2位的学者进行分析,纳入51个自变量。这些因素包括:(a)分为五个领域的国家决定因素(精神保健、性别平等、社会经济发展、预算政策和疾病负担),(b)从全球和特定学科排名中得出的制度因素,以及(c)性别和学龄的个人因素。主要指标为优秀精神病学学者(EPS)数量,次要指标包括被引次数、修正h指数、综合评分和自引份额。结果精神病学研究的卓越性主要集中在高收入、英语国家,且存在显著的制度精英主义。少数机构托管了不成比例的EPS份额。性别差异仍然存在,女性代表与就业和教育方面的国家性别差距负相关,但与政府教育支出呈正相关。学龄与基于引用的绩效指标正相关。多变量模型证实了性别、学龄、官方语言、性别平等和人类发展的解释作用。结论精神病学研究优势反映了与收入、语言、机构声望和性别平等相关的系统性优势。公平的资金、对新兴研究环境的支持以及扩大国际合作对于促进更广泛地参与高影响力的精神病学研究至关重要。
{"title":"National-, institutional-, and individual-level determinants of psychiatric research excellence: Analysis of Stanford-Elsevier lists of the top 2 % scholars worldwide (2017–2023)","authors":"Abanoub Riad ,&nbsp;Muhammad Alkasaby ,&nbsp;Nisarat Changchroenkul ,&nbsp;Michal Koščík","doi":"10.1016/j.ajp.2025.104826","DOIUrl":"10.1016/j.ajp.2025.104826","url":null,"abstract":"<div><h3>Background</h3><div>Research excellence is increasingly used as a benchmark for academic evaluation in medical sciences, including psychiatry. However, bibliometric analyses often prioritize productivity over quality. This study examined national, institutional, and individual determinants of psychiatric research excellence using a multi-level ecological framework.</div></div><div><h3>Methods</h3><div>We analyzed the Stanford–Elsevier Lists of the top 2 % scholars (2017–2023), incorporating 51 independent variables. These included: (a) national determinants grouped into five domains (mental healthcare, gender equity, socioeconomic development, budgetary policies, and disease burden), (b) institutional factors derived from global and discipline-specific rankings, and (c) individual factors of gender and academic age. The primary outcome was the number of excellent psychiatric scholars (EPS), with secondary indicators including citation counts, modified H-index, composite score, and self-citation share.</div></div><div><h3>Results</h3><div>Psychiatric research excellence was concentrated in high-income, English-speaking countries, with significant institutional elitism. A small number of institutions hosted a disproportionate share of EPS. Gender disparities persisted, with female representation negatively associated with national gender gaps in employment and education, but positively linked to government spending on education. Academic age positively correlated with citation-based performance metrics. Multivariable models confirmed the explanatory roles of gender, academic age, official language, gender equity, and human development.</div></div><div><h3>Conclusion</h3><div>Psychiatric research excellence reflects systemic advantages related to income, language, institutional prestige, and gender equity. Equitable funding, support for emerging research environments, and expanded international collaboration are essential to fostering broader participation in high-impact psychiatric research.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104826"},"PeriodicalIF":4.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145922134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acceptance of communication robots among patients undergoing maintenance hemodialysis with psychological stress 有心理压力的维持性血液透析患者对通讯机器人的接受程度。
IF 4.5 4区 医学 Q1 PSYCHIATRY Pub Date : 2026-01-02 DOI: 10.1016/j.ajp.2025.104811
Hirokazu Kumazaki, Hiroko Kamide, Megumi Kawata, Yuka Nakazawa, Shun Shimoguchi, Kenta Torigoe, Tomoya Nishino, Yuichiro Yoshikawa, Hiroshi Ishiguro

Objective

Although several psychotherapeutic interventions have been introduced for patients receiving maintenance hemodialysis (MHD), challenges such as feelings of shame persist. Prior studies indicate that robot-assisted interviews evoke less shame than human interactions. The Technology Acceptance Model (TAM) provides a robust framework for examining factors influencing technology adoption. This study applied TAM to evaluate the use of a communication robot (Sota-100) in psychotherapeutic interventions for patients with MHD.

Methods

Twenty-six outpatients with MHD participated. Each completed an interaction session with Sota-100 and a self-report questionnaire using a 5-point Likert scale.

Results

The intention to use Sota-100 counseling was significantly higher than that for human counseling (p = 0.003). A Wilcoxon signed-rank test confirmed that Sota-100 was easy to use (p = 0.023). Spearman’s correlation showed significant associations between ease of use and perceived usefulness in reducing anxiety and stress (p = 0.028), decreasing boredom and loneliness (p < 0.001), enhancing motivation for self-administration (p = 0.004), and intention to use Sota-100 (p = 0.005).

Conclusion

Most patients with MHD were receptive to Sota-100, supporting the applicability of TAM. Improving robot usability could further alleviate anxiety, stress, boredom, and loneliness, enhance self-management motivation, and strengthen patients’ willingness to engage with robotic support in psychosocial care.
目的:尽管对维持性血液透析(MHD)患者已经引入了几种心理治疗干预措施,但羞耻感等挑战仍然存在。先前的研究表明,与人类互动相比,机器人辅助面试引起的羞耻感更少。技术接受模型(TAM)为检查影响技术采用的因素提供了一个健壮的框架。本研究应用TAM来评估通信机器人(Sota-100)在MHD患者心理治疗干预中的应用。方法:对26例MHD门诊患者进行调查。每个人都完成了与Sota-100的互动会话和使用5分李克特量表的自我报告问卷。结果:使用Sota-100心理咨询的意向显著高于人类心理咨询(p = 0.003)。Wilcoxon sign -rank检验证实Sota-100易于使用(p = 0.023)。Spearman相关显示易用性与感知有用性在减轻焦虑和压力(p = 0.028)、减少无聊和孤独感(p )方面存在显著相关性。结论:大多数MHD患者接受Sota-100,支持TAM的适用性。提高机器人的可用性可以进一步缓解焦虑、压力、无聊和孤独,增强自我管理的动机,并增强患者在心理社会护理中使用机器人支持的意愿。
{"title":"Acceptance of communication robots among patients undergoing maintenance hemodialysis with psychological stress","authors":"Hirokazu Kumazaki,&nbsp;Hiroko Kamide,&nbsp;Megumi Kawata,&nbsp;Yuka Nakazawa,&nbsp;Shun Shimoguchi,&nbsp;Kenta Torigoe,&nbsp;Tomoya Nishino,&nbsp;Yuichiro Yoshikawa,&nbsp;Hiroshi Ishiguro","doi":"10.1016/j.ajp.2025.104811","DOIUrl":"10.1016/j.ajp.2025.104811","url":null,"abstract":"<div><h3>Objective</h3><div>Although several psychotherapeutic interventions have been introduced for patients receiving maintenance hemodialysis (MHD), challenges such as feelings of shame persist. Prior studies indicate that robot-assisted interviews evoke less shame than human interactions. The Technology Acceptance Model (TAM) provides a robust framework for examining factors influencing technology adoption. This study applied TAM to evaluate the use of a communication robot (Sota-100) in psychotherapeutic interventions for patients with MHD.</div></div><div><h3>Methods</h3><div>Twenty-six outpatients with MHD participated. Each completed an interaction session with Sota-100 and a self-report questionnaire using a 5-point Likert scale.</div></div><div><h3>Results</h3><div>The intention to use Sota-100 counseling was significantly higher than that for human counseling (p = 0.003). A Wilcoxon signed-rank test confirmed that Sota-100 was easy to use (p = 0.023). Spearman’s correlation showed significant associations between ease of use and perceived usefulness in reducing anxiety and stress (p = 0.028), decreasing boredom and loneliness (p &lt; 0.001), enhancing motivation for self-administration (p = 0.004), and intention to use Sota-100 (p = 0.005).</div></div><div><h3>Conclusion</h3><div>Most patients with MHD were receptive to Sota-100, supporting the applicability of TAM. Improving robot usability could further alleviate anxiety, stress, boredom, and loneliness, enhance self-management motivation, and strengthen patients’ willingness to engage with robotic support in psychosocial care.</div></div>","PeriodicalId":8543,"journal":{"name":"Asian journal of psychiatry","volume":"116 ","pages":"Article 104811"},"PeriodicalIF":4.5,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145916650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Asian journal of psychiatry
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