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MODERN PRINCIPLES AND TECHNOLOGIES OF THE TREATMENT OF THE WOUNDED WITH INJURIES OF MUSCULOSKELETAL SYSTEM 肌肉骨骼系统损伤伤员的现代治疗原则与技术
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.148
Trukhan A. P.
On December 1–3, 2022, the XII All-Russian Congress of Traumatologists and Orthopedists was held in Moscow (Russian Federation), one of the topics of which was the principles of treatment of the wounded with injuries of musculoskeletal system.
2022年12月1日至3日,第十二届全俄创伤学家和骨科医生大会在莫斯科(俄罗斯联邦)举行,其中一个主题是治疗肌肉骨骼系统损伤的伤者的原则。
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引用次数: 0
SUBCLINICAL HYPOTHYROISIS 亚临床HYPOTHYROISIS
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.40
Lobanova M. V., Kacherovskaya E. R.
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引用次数: 0
CLINICAL AND LABORATORY PREDICTORS OF RAPID PROGRESSION OF PARKINSON’S DISEASE 帕金森病快速进展的临床和实验室预测因素
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.79
Boika A. V.
In Parkinson's disease (PD), several types of progression are conditionally distinguished. Determination of reliable criteria for identifying patients with a rapid type of PD progression in the early stages of the disease will allow us to begin the development of therapy aimed at inhibiting its development. The aim of the study was to determine the clinical and laboratory predictors of the rapid type of PD progression in the Belarusian cohort of patients. Patients with PD underwent a general somatic and neurological examination. Non-motor symptoms were assessed by completing the appropriate scales. Laboratory studies included the determination of antibodies to α-synuclein, the study of the levels of cortisol, IL-1β and IL-10, the calculation of the albumin coefficient (Qalb). Longitudinal study with three groups: 1) rapidly progressive type of PD, 2) slowly progressive, and 3) indeterminate. Candidate predictors were obtained by comparing clinical and laboratory parameters of patients with fast or slow types of PD progression. During dynamic monitoring of patients with an indeterminate type of progression, the sensitivity and specificity of predictors were determined. 113 people with PD: group 1 – 32 patients, group 2 – 26, group 3 – 55. Threshold values of indicators were obtained by comparing the clinical and laboratory characteristics of groups 1 and 2 by the Mann-Whitney method and then by ROC analysis to determine the probability of a fast type progression : Qalb less than 83.95, antibodies to α-synuclein in serum more than 4.11 ng/ml, MoCA less than 26 points. Depending on these indicators, patients of group 3 were divided into 2 subgroups: 3a) "possibly rapidly progressive" course (n = 21) and 3b) "possibly slowly progressive" course of PD (n = 34). In 16 (76%) patients from group 3a, the rapid type of progression was confirmed. In 28 (82%) patients from group 3b, a slow type of progression was confirmed. The obtained results testify to the high sensitivity and specificity of the indicators. Further research is needed to develop therapies that change the course of PD.
在帕金森病(PD)中,几种类型的进展是有条件区分的。在疾病的早期阶段,确定确定PD快速发展患者的可靠标准将使我们能够开始开发旨在抑制其发展的治疗方法。该研究的目的是确定白俄罗斯患者队列中PD快速进展的临床和实验室预测因素。PD患者接受全身和神经系统检查。通过完成相应的量表来评估非运动症状。实验室研究包括α-突触核蛋白抗体的测定,皮质醇、IL-1β和IL-10水平的研究,白蛋白系数(Qalb)的计算。纵向研究分为三组:1)快速进展型PD, 2)缓慢进展型PD, 3)不确定型PD。通过比较快速或缓慢型PD患者的临床和实验室参数获得候选预测因子。在对不确定进展类型的患者进行动态监测期间,确定了预测因子的敏感性和特异性。113例PD患者:1 ~ 32例,2 ~ 26例,3 ~ 55例。采用Mann-Whitney法比较1组和2组患者的临床和实验室特征,得出各项指标的阈值,然后进行ROC分析,确定快速型进展的概率:Qalb < 83.95,血清α-synuclein抗体> 4.11 ng/ml, MoCA < 26分。根据这些指标将第3组患者分为2个亚组:3a)“可能快速进展”病程(n = 21)和3b)“可能进展缓慢”的PD病程(n = 34)。在3a组的16例(76%)患者中,证实了快速进展型。3b组28例(82%)患者证实进展缓慢。结果表明,该指标具有较高的灵敏度和特异性。需要进一步的研究来开发改变PD病程的治疗方法。
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引用次数: 0
PROBLEMS OF DIAGNOSTICS AND TREATMENT OF FOURNIER'S GANGRENE 富尼耶坏疽的诊断与治疗问题
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.1.87
Danilchyk A. V., Kuzmin Yu. V., Zhidkov A. S.
Fournier's gangrene is a rare disease with a severe course and high mortality, the prognosis of which depends on timely diagnosis and timing of surgical intervention. Nonspecific clinical manifestations and the rapid development of the inflammatory process create certain difficulties for surgeons in making the correct diagnosis and treating such patients. This review presents the issues of diagnosis and treatment of Fournier's gangrene at the present stage of development of medicine.
富尼耶坏疽是一种病程严重、死亡率高的罕见疾病,其预后取决于及时诊断和手术干预的时机。非特异性临床表现和炎症过程的快速发展给外科医生正确诊断和治疗此类患者带来了一定的困难。本文就目前医学发展阶段对富尼耶坏疽的诊断和治疗问题作一综述。
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引用次数: 0
SUBJECTIVE ASSESSMENT OF MEDICAL MASK OPERATING CONDITIONS BY MEDICAL PROFESSIONALS DURING THE COVID-19 PANDEMIC COVID-19大流行期间医护人员医用口罩操作条件的主观评价
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.1.41
Semushyna E. A., Tolkach S. N., Siniakova O. K., Shcherbinskaya E. S.
Specialists of the republican unitary enterprise "Scientific and Practical Centre of Hygiene" have developed a questionnaire that allows medical workers of healthcare organizations of outpatient and inpatient profile to assess the body’s state during the operation of medical masks in a favorable and unfavorable epidemic situation. 270 medical workers were interviewed, of which physicians – 24%, middle medical staff – 60%, junior medical staff – 16%. The survey showed that the operation time of medical devices for respiratory tract protection in an unfavorable epidemic situation exceeds than in a favorable epidemic situation both in outpatient and polyclinic healthcare organizations and in inpatient healthcare organizations. Increasing operation time of medical devices for respiratory tract protection during one work shift is accompanied by increasing number of symptoms of the fatigue process and their severity. In this case, the nature of these symptoms is different for medical workers of various health care organizations.
共和国统一企业"卫生科学和实践中心"的专家编制了一份调查表,使门诊和住院医疗机构的医务人员能够评估在有利和不利的流行病情况下使用医用口罩期间的身体状态。对270名医务人员进行了访谈,其中医生占24%,中级医务人员占60%,初级医务人员占16%。调查显示,门诊、综合门诊医疗机构和住院医疗机构在疫情不利情况下使用呼吸道保护医疗器械的时间均大于疫情有利情况下使用呼吸道保护医疗器械的时间。在一个班次中,用于呼吸道保护的医疗器械操作时间的增加伴随着疲劳过程中症状的增加和严重程度的增加。在这种情况下,这些症状的性质对于各个卫生保健机构的医务工作者来说是不同的。
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引用次数: 0
SOCIO-BEHAVIORAL ASPECTS OF THE PREVALENCE OF IRRITABLE BOWEL SYNDROME AMONG MILITARY SERVICEMEN AND THEIR FAMILY MEMBERS 军人及其家庭成员肠易激综合征患病率的社会行为方面
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.10
Halafova R. N.
Objective. Identification and assessment of socio-behavioral risk factors for the formation of irritable bowel syndrome (IBS) among military personnel and members of their families (ARC). Material and technique. IBS was diagnosed according to Rome IV criteria. The level of emotional stress (ES) on the Rider scale. A total of 1977 cadets (aged 17–22) were examined. 326 officers (aged 24–55) and 257 of their wives (aged 23–51). Results and discussion. The detection rate of IBS among SCD varies from 18.7±2.2 to 22.2±2.6% (P > 0.05). IBS-C (constipation) is most often detected than IBS-D (diarrhea), because patients with diarrhea are more likely to visit doctors and receive treatment. In general, the medical negotiability of patients is poor and averages 30.7±2.3%, and 37.3±2.4% of patients carry out self-treatment, another 32.0±2.3% of patients tolerate the clinical manifestations of IBS (P > 0.05). When IBS is combined with other syndromes, medical negotiability increases to 62.1±9.2%. During the period of adaptation to the conditions of life and study at the school, the level of strong ES in cadets increases to 32.3±2.3%, as adaptation (after 4 years) it decreases to 3.4±1.1% (P < 0.001) . The incidence of IBS is higher in patients with poor housing conditions, incomplete marital status and tobacco addiction. Conclusion. Effective management of the identified socio-behavioral risk factors for the formation of IBS can significantly reduce the risk of SCD and their families with IBS.
目标。军人及其家属肠易激综合征(IBS)形成的社会行为危险因素的识别和评估材料和技术。IBS是根据Rome IV标准诊断的。骑手量表中的情绪压力水平(ES)。共测试了1977名学员(17-22岁)。326名人员(24至55岁)和257名他们的妻子(23至51岁)。结果和讨论。SCD患者IBS检出率为18.7±2.2 ~ 22.2±2.6% (P < 0.05)。IBS-C(便秘)比IBS-D(腹泻)更常被发现,因为腹泻患者更有可能去看医生并接受治疗。总体而言,患者的医疗可协商性较差,平均为30.7±2.3%,37.3±2.4%的患者进行了自我治疗,另有32.0±2.3%的患者能够忍受IBS的临床表现(P < 0.05)。当IBS合并其他综合征时,医疗可协商性增加到62.1±9.2%。在适应学校生活和学习条件期间,学员的强ES水平上升到32.3±2.3%,在适应4年后下降到3.4±1.1% (P < 0.001)。居住条件差、婚姻状况不完整和吸烟成瘾的患者IBS发病率较高。结论。有效管理已确定的肠易激综合征形成的社会行为风险因素,可以显著降低SCD及其家庭患肠易激综合征的风险。
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引用次数: 0
THE INFLUENCE OF PHYSICO-PHARMACOLOGICAL EFFECTS ON THE CALCIUM CONTENT IN THE BLOOD SERUM OF EXPERIMENTAL ANIMALS 物理药理作用对实验动物血清钙含量的影响
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.63
Ivashenko S. V.
The use of intraosseous dental implants allows solving many issues with partial and complete loss of teeth, restoring chewing function and improving facial aesthetics. And the rapid formation of a strong connection between the implant and the bone is the key to a successful result of the dental surgery. In this regard, it is of interest to develop a method for improving the biointegration of dental implants using magnetophoresis of medicinal substances, which significantly increases therapeutic efficacy. However, the issues of calcium content in its serum under the influence of the used therapeutic agents (surgical, physiotherapeutic, pharmacological) have not been sufficiently studied. Therefore, the purpose of this study was to determine the calcium content in the blood serum of experimental animals after the application of magnetophoresis solutions of 10% calcium gluconate and 5% retabolil. 16 rabbits of the "chinchilla" breed served as objects for fulfilling the goal of our work. The study made it possible to conclude that the magnetophoresis effects of calcium gluconate and retabolil solutions did not lead to a change in blood biochemistry and contributed to a short-term increase in the content of calcium and phosphorus in the blood serum of animals.
使用骨内种植体可以解决部分或完全牙齿缺失的许多问题,恢复咀嚼功能并改善面部美观。在植体和骨骼之间迅速形成牢固的连接是牙科手术成功的关键。在这方面,开发一种利用药物磁泳的方法来改善种植体的生物整合,从而显着提高治疗效果是值得关注的。然而,在所用治疗剂(外科、物理治疗、药理学)的影响下,其血清中钙含量的问题尚未得到充分研究。因此,本研究的目的是测定10%葡萄糖酸钙和5%代谢素的磁泳液应用后实验动物血清中的钙含量。16只“栗鼠”品种的兔子作为完成我们工作目标的对象。该研究可以得出这样的结论:葡萄糖酸钙和代谢剂溶液的磁泳作用不会导致血液生化变化,而是导致动物血清中钙和磷含量的短期增加。
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引用次数: 0
ENTEROPATHY WITH IMPAIRED MEMBRANE DIGESTION AND IRRITABLE BOWEL SYNDROME – COMBINED PATHOLOGY 肠病伴膜消化障碍和肠易激综合征-合并病理
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.2.96
Kurchenkova V. I., Kapralov N. V., Shalamitskaya-Huleviсh I. A.
The article describes the clinical manifestations and their causes in the pathology of the small intestine in patients who complain of excessive bloating, recurrent abdominal pain syndrome, stool disorders with a tendency to relaxation. Such patients repeatedly return to the doctor. The evidence of a decrease in the activity of disaccharidases in this cohort of patients is presented. The emphasis is placed on the need to study the nutritional history, to identify products that provoke a violation of membrane digestion. The classification of carbohydrates with indication of products containing them is given. The essence of repeated and persistent clinical manifestations due to impaired membrane digestion and absorption of carbohydrates in the small intestine is explained, which leads to their appearance in the large intestine in different volumes, which is accompanied by the splitting of carbohydrates with the formation of gases. On the one hand, this is a normal process, but when it gets out of control, the patient gets to the doctor. The essence of a carbohydrate–restricted diet is described - this is the low FODMAP diet and its decoding. The products containing oligosaccharides are indicated, which are capable of being cleaved by the enzyme alpha-galactosidase, which is absent in the human body, but is present in the microflora of the large intestine. Advice is given on limiting the intake of such products, both in terms of the frequency of intake and the volume of portions containing them, in order to avoid excessive amounts of intestinal gases, the development of a clinically painful condition. A thorough study of the nutritional history and the necessary correction of eating behavior is the main idea of this article, dedicated to the same type of clinical picture with varying degrees of manifestations of its symptoms.
本文叙述了以过度腹胀、反复腹痛综合征、大便紊乱伴松弛倾向为主诉的小肠病理的临床表现及其原因。这样的病人反复去看医生。证据表明,在这组患者中,双糖酶的活性降低。重点放在需要研究的营养历史,以确定产品,挑起违反膜消化。给出了碳水化合物的分类和含有碳水化合物的产品的指示。解释了小肠碳水化合物膜消化吸收功能受损,导致其在大肠中以不同体积出现,并伴随碳水化合物分裂形成气体的临床表现反复持续的本质。一方面,这是一个正常的过程,但当它失去控制时,病人就会去找医生。碳水化合物限制饮食的本质是描述-这是低FODMAP饮食及其解码。含有低聚糖的产品被指出,它能够被酶-半乳糖苷酶裂解,这种酶在人体中不存在,但存在于大肠的微生物群中。建议限制这类产品的摄入,包括摄入的频率和含有它们的部分的体积,以避免过量的肠道气体,发展临床疼痛状况。对营养史的深入研究和饮食行为的必要纠正是本文的主要思想,致力于同一类型的临床图片,不同程度的表现其症状。
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引用次数: 0
SANATORIUM STAGE OF TREATMENT OF NIGHT ENUREZIS IN PERSONS OF PRE-CONSCEPTION AGE 孕前年龄夜遗尿的疗养院分期治疗
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.1.128
Kaminsky A. N., Terekhovich T. I., Shnitko S. N., Maksimovich M. M.
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引用次数: 0
THE METHOD OF SHOC-WAVE THERAPY IN PRACTICE OF THE PHYSIOTHERAPIST 物理治疗师在实践中的冲击波治疗方法
Pub Date : 2023-01-01 DOI: 10.51922/2074-5044.2023.1.59
Mogilevitch V. V., Khrenina N. M.
In the article gives information on the therapeutic application of the shock-wave method, based on the transfer of energy of the shock-wave pulse from the apparatus’s contact hеad (nozzle) of the applicator to the tissues of the human body. The perspectivity et high efficiency of using the method shock-wave therapy of clinical practices of the physiotherapist.
本文介绍了冲击波法的治疗应用,其原理是将冲击波脉冲的能量从装置的接触喷头(喷嘴)传递到人体组织。物理治疗师在临床实践中运用冲击波疗法的前瞻性和高效性。
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引用次数: 0
期刊
Military surgeon
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