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Cover Page Vol. 2(1) 封面第二卷(1)
Pub Date : 2023-11-12 DOI: 10.3329/bsmmcj.v2i1.69603
M M Shahin Ul Islam
Abstract not available Cover Page of January 2023
2023年1月封面
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引用次数: 0
Diaphragmatic Hernia (Bochdalek Hernia) in an Adult: a Case Report 成人膈疝(Bochdalek疝)1例报告
Pub Date : 2023-11-12 DOI: 10.3329/bsmmcj.v2i1.69602
Ratan Kumar Saha, A S M Tanjilur Rahman, Dipankar Roy, Abu Saleh Ahmed, Adnan Tarif, Md Tofazzal Hussain, Sumit Saha
Bochdalek hernia (BH) is the most common type of congenital diaphragmatic hernia and constitutes 85% of cases. In adults BH is extremely rare. Most of them are asymptomatic. We present a case of BH in an adult patient to point out the importance of clinical examination and computed tomography (CT) scan in reaching the exact diagnosis. A 17-year-old male was presented to the surgery department with a 3-days history of recurrent abdominal pain, vomiting and unable to lie flat. The BH was confirmed on computed tomography (CT) imaging and the patient underwent emergency laparotomy and per-operatively we found part of stomach, greater omentum, splenic flexure of colon along with spleen herniated into the left hemithorax through a defect of approximately 8x6cm in the left postero-lateral aspect of the diaphragm. Reduction of hernia contents and surgical repair of the defect was done with non-absorbable suture. His post-operative period was uneventful. Although rare, this disorder should be recognized and treated appropriately to avoid complications. Bangabandhu Sheikh Mujib Med. Coll. J. 2023;2(1): 64-67
Bochdalek疝(BH)是最常见的先天性膈疝类型,占85%的病例。成人BH极为罕见。他们中的大多数是无症状的。我们在此报告一个成人BH病例,以指出临床检查和计算机断层扫描(CT)在达到准确诊断中的重要性。一名17岁男性因反复腹痛、呕吐和无法平躺3天来到外科。经计算机断层扫描(CT)证实,患者接受了紧急剖腹手术,术中我们发现部分胃、大网膜、结肠脾曲以及脾脏通过膈左后外侧约8x6cm的缺损疝入左半胸。用不可吸收缝线减少疝内容物并手术修复缺损。他的术后生活平安无事。虽然罕见,这种疾病应该认识和适当治疗,以避免并发症。Bangabandhu Sheikh Mujib Med. col。[j]; 2009;2(1): 64-67
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引用次数: 0
Risk Factors of Birth Defects: A Case-control Study in a Tertiary Level Hospital 某三级医院出生缺陷危险因素的病例对照研究
Pub Date : 2023-11-12 DOI: 10.3329/bsmmcj.v2i1.69596
Mohammad Delwar Hossain, Md Abdul Qyuoom, Abu Shoyeb Md Mahamuduzzaman, Imam Uddin Md. Abu Kawsar Mir, Kamrul Ahsan, Abu Faisal Md Pervez, Begum Sharifun Nahar
Worldwide birth defects are one of the main causes of morbidity and disability among children. The risk factors vary significantly by geography, depending on local environmental and genetic factors. Our aim was to ascertain the local risk factors for birth defects, which is the first step toward devising preventive policies. From February 2018 to October 2019, this case-control study was undertaken at Sir Salimullah Medical College and Mitford Hospital, Dhaka, in the Department of Neonatology and Obstetrics. During this period 49 admitted newborns with birth abnormalities were selected as cases, and children of similar gestational age, sex, and post-natal age were selected as controls for each case. To determine the risk factors for birth abnormalities, in-depth interviews with mothers regarding their demographic and obstetric histories were recorded and analyzed. We found that mothers aged 26-30 years had a significantly increased risk of birth defects (p = 0.01). Additionally, mothers who had a history of diabetes had a considerably higher risk of delivering a child with birth defects (p = 0.03). During the pregnancy period, mothers who attended <4 antenatal care (ANC) visits and mothers who did not take iron or folic acid supplementation had a higher risk of birth defects (p = 0.02 and p <0.01, respectively).We found out that the majority of birth defect risk factors are preventable or controllable. By promoting appropriate antenatal care and educating mothers about relevant regional risk factors, the occurrence of birth defects can be lowered significantly. Bangabandhu Sheikh Mujib Med. Coll. J. 2023;2(1): 33-39
在世界范围内,出生缺陷是儿童发病和残疾的主要原因之一。风险因素因地域而异,取决于当地的环境和遗传因素。我们的目的是确定当地出生缺陷的危险因素,这是制定预防政策的第一步。2018年2月至2019年10月,这项病例对照研究是在达卡萨里穆拉爵士医学院和米特福德医院新生儿和产科进行的。在此期间,选择49例出生异常的住院新生儿作为病例,并选择相似胎龄、性别和出生后年龄的儿童作为每个病例的对照。为了确定出生异常的危险因素,对母亲进行了深入访谈,记录和分析了她们的人口统计学和产科史。我们发现26-30岁的母亲出生缺陷的风险显著增加(p = 0.01)。此外,有糖尿病史的母亲生下有先天缺陷孩子的风险要高得多(p = 0.03)。在怀孕期间,参加产前保健(ANC)检查的母亲和未补充铁或叶酸的母亲有更高的出生缺陷风险(p = 0.02和p <0.01)。我们发现,大多数出生缺陷的危险因素是可以预防或控制的。通过促进适当的产前保健和教育母亲有关的区域危险因素,可以大大降低出生缺陷的发生率。Bangabandhu Sheikh Mujib Med. col。[j] .生物工程学报;2009;2(1):33-39
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引用次数: 0
Outcome of Placenta Percreta Management by Planned Peripartum Hysterectomy in a Tertiary Level Hospital 某三级医院计划围产期子宫切除术治疗先天性胎盘的效果
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69345
Fahmida Zesmin, Dilruba Zeba, Rajib Biswas, Kaneez Fatema, Samiya Alam, Shafeya Khanam
The incidence of placenta accreta spectrum is gradually increasing due to increased rate of caesarean sections (CS). Due to torrential haemorrhage, placenta percreta is one of the main reasons for emergency peripartum hysterectomies and mostly results in subsequent maternal mortalities and morbidities. In such cases, caesarean hysterectomy leaving the placenta in situ without any separation of placenta is preferred. We observed the outcome of such patients managed with planned caesarean hysterectomy. This cross-sectional observational study was conducted at the Department of Obstetrics, Faridpur Medical College Hospital, Bangladesh. A total of 14 patients who underwent planned caesarean hysterectomy due to placenta percreta were studied. We performed delivery of the baby through upper segment transverse incision without placental separation. The umbilical cord was ligated leaving the placenta in the uterine cavity and cut margins of the uterus was closed with few interrupted sutures and then hysterectomy was performed. Among 14 cases, the mean age was 30 years, mean gestational age at the time of delivery was 36 weeks, and all had a history of one or more CS. Before operation, mean Hb% was 8.9 g/dl. A mean of 1.5 units pre-operative and 1.2 units post-operative blood transfusions was needed. Post-operative mean Hb% was 10.5 gm/dl. Half of the women were discharged on their 3rd post-operative day. None of them had serious pre- and post-operative complications. In light of our findings, we recommend managing placenta percreta by planned caesarean hysterectomy with the placenta left in situ to minimise blood loss and subsequent maternal mortality and morbidity. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):80-84
随着剖宫产率的增加,增胎谱的发病率逐渐增加。percreta胎盘是围产期紧急子宫切除术的主要原因之一,是导致产妇死亡和发病的主要原因之一。在这种情况下,剖腹产子宫切除术保留胎盘原位而不分离胎盘是首选。我们观察了这些患者计划剖宫产子宫切除术的结果。这项横断面观察性研究是在孟加拉国法里德普尔医学院医院产科进行的。我们对14例因percreta胎盘而行剖宫产子宫切除术的患者进行了研究。我们采用无胎盘分离的上节段横切口分娩。结扎脐带,将胎盘留在子宫腔内,关闭子宫切口,缝线很少中断,然后行子宫切除术。14例患者平均年龄30岁,分娩时平均胎龄36周,均有一种或多种CS病史。术前平均Hb%为8.9 g/dl。术前平均输血1.5单位,术后平均输血1.2单位。术后平均Hb%为10.5 gm/dl。半数患者在术后第3天出院。手术前后均无严重并发症。根据我们的研究结果,我们建议通过有计划的剖宫产子宫切除术来处理perperte胎盘,并保留胎盘,以尽量减少失血和随后的孕产妇死亡率和发病率。 Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 80 - 84
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引用次数: 0
Prevalence of Hearing Loss among Noise Exposed Industrial Workers 受噪音影响的工业工人听力损失的患病率
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69347
Md Shafiq Ur Rahman, Nripendra Nath Biswas, Shahbub Alam, Debabrota Roy, ATM Sumaief Ur Rahman, Ranjit Kumar Rudra, BM Lutfar Rahman, Md Muktadir Arefin, Molla Sharfuddin Ahmad, S M Munawar Murshed
Exposure to any type of noise has a potential risk. Higher the level of noise and longer duration of exposure, more the risk for hearing sensitivity and health as a whole. Occupational noise induced hearing loss (ONIHL) is a major cause of disability throughout the world. So this study was designed to know the prevalence of NIHL among the noise exposed industrial workers in Bangladesh. A prospective observational study of 377 People working at industrial environment in Jute mills at Faridpur region were studied between January 2021 to June 2021. Data collected from each respondent recorded on a predesigned data collection form. Pure tone audiometry was performed in both ears. Among 377 study population, 157(41.6%) subjects had hearing loss and 220 subjects (58.4%) had no loss. Among the workers with hearing loss, 98(62.4%) got hearing loss on both sides, 32(20.4%) on the right side and 27(17.2%) on the left side. Among them 83(52.9%) had mild hearing loss, 37(23.6%) had moderate hearing loss, 31(19.7%) had severe hearing loss and 6(3.8%) had profound hearing loss. The average duration of work in the industry was 6.94±5.64 years and majority (78.5%) had 8 hours working hour per day and 21.5% had more than 8 hours. The average sound intensity was 91.51±8.12 dB(A) with 10.9% exposed to <_85 dB(A) and 89.1% to >85 dB(A). This study shows Noise-induced hearing loss (NIHL)as highly prevalent among noise-exposed workers in Bangladesh. Age >35 years, high noise level, exposure of more than 10 years, were significantly associated with increased risk of hearing loss. The local and national authority should focus on noise monitoring, engineering modifications of buildings and machinery, occupational safety policies, administrative controls, providing education on NIHL, periodic audiometric assessments and follow-up evaluation for hearing threshold shift. This study supported the elements for further research studies related to the employer compliance with occupational health and safety regulations to address awareness of their responsibility in minimizing hazards in workplaces. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(1):90-95
接触任何类型的噪音都有潜在的危险。噪音水平越高,暴露时间越长,听力灵敏度和整体健康的风险就越大。职业性噪声引起的听力损失(ONIHL)是全世界致残的一个主要原因。因此,本研究旨在了解噪声暴露的孟加拉国工业工人中NIHL的患病率。在2021年1月至2021年6月期间,对在法里德普尔地区黄麻厂工业环境中工作的377人进行了前瞻性观察研究。从每个受访者收集的数据记录在预先设计的数据收集表格上。双耳纯音测听。在377例研究人群中,157例(41.6%)有听力损失,220例(58.4%)无听力损失。听力损失工人中,两侧听力损失98人(62.4%),右侧听力损失32人(20.4%),左侧听力损失27人(17.2%)。其中,轻度听力损失83例(52.9%),中度听力损失37例(23.6%),重度听力损失31例(19.7%),重度听力损失6例(3.8%)。该行业的平均工作时间为6.94±5.64年,大多数(78.5%)每天工作时间为8小时,21.5%的人每天工作时间超过8小时。平均声强为91.51±8.12 dB(A),其中10.9%暴露于<_85 dB(A), 89.1%暴露于>85 dB(A)。本研究表明噪声性听力损失(NIHL)在孟加拉国噪声暴露工人中非常普遍。年龄35岁,高噪音水平,接触超过10年,与听力损失风险增加显著相关。地方和国家当局应侧重于噪音监测、建筑物和机械的工程改造、职业安全政策、行政控制、提供关于非自然灾害的教育、定期听力学评估和听力阈值转移的后续评价。这项研究支持了与雇主遵守职业健康和安全条例有关的进一步研究的要素,以提高他们在尽量减少工作场所危害方面的责任意识。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (1): 90 - 95
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引用次数: 0
Mode, Pattern and Precipitating factors of Acute Poisoning in a Southern District Hospital in Bangladesh 孟加拉国南区医院急性中毒的模式、模式和诱发因素
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69346
Suranjit Kumar Saha, M M Shahin Ul Islam, Md Hasnat Yousuf Zaki, Md Nizam Uddin, Mohammad Rezaul Quader, Sharmin Rahman, Prativa Saha, Molla Sharfuddin Ahmad
Acute poisoning is common in Bangladesh and causes a significant number of hospital admissions. That causes anumber of mortality, morbidity as well as increases the economic burden in health care system. But it can beprevented. For that it is necessary to observe and study the poisoning related factors and events around the country.So, the aim of our study is to find out and describe the mode, pattern and precipitating factors of poisoning in asouthern district hospital. This cross-sectional observational study was done in the department of Medicine ofPirojpur District Hospital, from January to December 2020. The study was conducted among 100 patients of bothgenders those were hospitalized with the history of poisoning. In the study young people (40% in 14-25 years and37% in 26-35 years) were predominantly affected and 61% were female. Suicidal attempt was the commonest(74;74%) mode of poisoning that mostly caused by pesticides. Stupefying mode was observed in case of 15(15%)male travelers as street poisoning. Highest number of poisoning (45;45%) was caused by pesticides. The sedative(14;14%), copper sulphate (11;11%) and harpic (5;5%) poisoning was observed mostly as a suicidal mode. Historyof savlon (4;4%) and Kerosene (2;2%) poisoning was found as an accidental mode. As a recreational mode two malewere admitted with alcohol poisoning. Considering the precipitating factor, maximum cases (54;54%) had the historyof unsatisfactory family events. Street poisoning (15;15%) was precipitated by the careless behavior of travelers.Accidental poisoning (9,9%) was invited by unmindful and hurried attitude. Problem related to love and affair wasobserved in 8(8%) cases. Study and examination result precipitated poisoning in 7(7%) cases. History of job andincome dissatisfaction was found in 4(4%) cases. So those factors related with the poisoning should be considered.That will help to make a comprehensive strategy in order to resist these preventable events. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(1):85-89
急性中毒在孟加拉国很常见,导致大量患者入院。这导致了大量的死亡率和发病率,并增加了卫生保健系统的经济负担。但这是可以预防的。因此,有必要对全国各地的中毒相关因素和事件进行观察和研究。因此,我们的研究目的是了解和描述南区医院中毒的模式、模式和诱发因素。这项横断面观察性研究于2020年1月至12月在pirojpur地区医院医学系进行。该研究是在100名因中毒病史住院的男女患者中进行的。在这项研究中,年轻人(14-25岁占40%,26-35岁占37%)主要受影响,61%为女性。自杀是最常见的中毒方式(74%),主要由农药引起。街头中毒15例(15%)男性旅客观察到麻木模式。农药中毒人数最多(45例;45%)。镇静(14;14%)、硫酸铜(11;11%)和迷幻药(5;5%)中毒主要被视为自杀方式。发现萨隆(4.4%)和煤油(2.2%)中毒史为意外模式。作为娱乐方式,两名男性因酒精中毒而入院。考虑到诱发因素,有不满意家庭事件史的病例最多(54例;54%)。街头中毒(15.15%)是由于旅行者的不小心行为而导致的。意外中毒(9.9%)是由于粗心大意和匆忙的态度引起的。8例(8%)出现与恋爱和外遇有关的问题。研究及检查结果为中毒7例(7%)。4例(4%)患者有工作和收入不满史。所以这些与中毒有关的因素应该被考虑在内。这将有助于制定一项全面战略,以抵御这些可预防的事件。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (1): 85 - 89
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引用次数: 0
Thyroid Ultrasound Elastography: A Promising Undeniably Diagnostic Tool for Predicting the Risk of Malignancy 甲状腺超声弹性成像:一种预测恶性肿瘤风险的不可否认的有前途的诊断工具
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69348
Hafizur Rahman
Thyroid disease is of common occurrence, especially in iodine deficient areas. Thyroid nodules are common findings in the general population. It is important to distinguish the subset of thyroid nodules that are malignant, as morbidity and mortality from thyroid cancer increases with disease stage. B-mode ultrasound features are initially used to select thyroid nodules for FNA. Although FNA is considered the gold standard for diagnosis, it is yet imperfect as up to 1530% of samples are considered non-diagnostic or indeterminate. Thyroid ultrasound elastography(USE) is a noninvasive method of assessing thyroid nodules that provides complementary information to B-mode ultrasound and FNA. The combined use of thyroid USE with B-mode ultrasound may improve the ability to discriminate benign from malignant thyroid nodules and reduce the number of needed FNAs. Thyroid USE may also aid with the difficult problem of distinguishing between malignant and benign follicular neoplasm.The elastic properties of tissue have always been of interest in clinical practice. In the past, the identification of structures that were stiffer on physical palpation would raise the suspicion. With the development and advancement of medicine, there proved to be a true correlation in the prediction of malignancy of lesion: malignant disease tends to stiffen the affected tissue, either by increased cell proliferation or fibrosis. Palpation is the oldest method for the detection of thyroid nodules, which if informed by the knowledge that malignant thyroid lesions tend to be much harder than benign ones. Palpation is dependent on the size, location and skill of the physician. Nodules are very small or located in deep regions; there detection by palpation is difficult or even impossible. Although malignant lesion differs in terms of elasticity, it may not have echogenic properties, preventing its detection by conventional ultrasound. Imaging that indicates the stiffness or deformation related to their structural formation. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):96-98
甲状腺疾病是常见病,特别是在缺碘地区。甲状腺结节是普通人群的常见发现。区分甲状腺结节的恶性亚群是很重要的,因为甲状腺癌的发病率和死亡率随着疾病分期的增加而增加。b超特征最初用于选择甲状腺结节进行FNA。虽然FNA被认为是诊断的金标准,但它仍然是不完美的,因为多达1530%的样本被认为是不可诊断或不确定的。甲状腺超声弹性成像(USE)是一种评估甲状腺结节的无创方法,为b超和FNA提供了补充信息。甲状腺use与b超联合使用可以提高甲状腺结节良恶性的鉴别能力,减少所需FNAs的数量。甲状腺的使用也可能有助于区分恶性和良性滤泡肿瘤的难题。组织的弹性特性一直是临床研究的热点。在过去,通过物理触诊识别较硬的结构会引起怀疑。随着医学的发展和进步,病变的恶性预测确实存在相关性:恶性疾病倾向于使受累组织变硬,要么是细胞增殖增加,要么是纤维化增加。触诊是检测甲状腺结节最古老的方法,如果了解到恶性甲状腺病变往往比良性甲状腺病变困难得多。触诊取决于医生的大小、位置和技术。结节很小或位于深部;在这种情况下,通过触诊检测是困难的,甚至是不可能的。虽然恶性病变在弹性上有所不同,但它可能没有回声特性,无法通过常规超声检测到。显示与其结构形成相关的刚度或变形的成像。 Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 96 - 98
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引用次数: 0
COVID-19 and Diabetes: Acknowledging the Bidirectional Link 2019冠状病毒病与糖尿病:承认双向联系
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69349
Mohammad Rezaul Quader, Mohammad Jahidur Rahman Khan, Arifa Akram, Md Shahidul Islam, Nusrat Mannan, Md Sabir Hossain, Nurul Karim, Farha Matin Juliana, Amirul Huda Bhuiyan, Paroma Deb, Farhana Khatoon, Farzana Mim, Md Selim Reza
COVID-19 and diabetes mellitus have a dynamic and bidirectional relationship. Diabetes is a risk factor for COVID19. Diabetes mellitus is linked to hypercoagulability, inflammation, hyperglycemia, and other conditions (obesity, hypertension, cardiovascular disease, chronic kidney disease). Hyperglycemia may worsen SARS-CoV-2 infection. As a result of direct pancreatic damage caused by COVID-19, the stress response is triggered response to infection (including cytokine storm), including the use of hyperglycemic prescription medications such as corticosteroids for severe COVID-19, new-onset hyperglycemia and diabetes have been linked to the virus, as well as rapidly deteriorating blood glucose control in pre-existing diabetes. Insulin resistance and decreased b-cell secretion cause hyperglycemia. Challenges still remain in establishing the connection between COVID-19 and diabetes, whilst the pandemic progresses. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):99-103
COVID-19与糖尿病存在动态的双向关系。糖尿病是covid - 19的一个危险因素。糖尿病与高凝、炎症、高血糖和其他疾病(肥胖、高血压、心血管疾病、慢性肾病)有关。高血糖可能加重SARS-CoV-2感染。由于COVID-19造成的直接胰腺损伤,应激反应是对感染(包括细胞因子风暴)的触发反应,包括使用糖皮质类固醇等高血糖处方药治疗严重的COVID-19,新发高血糖和糖尿病与该病毒有关,以及已经存在的糖尿病患者血糖控制迅速恶化。胰岛素抵抗和b细胞分泌减少引起高血糖。随着大流行的进展,在建立COVID-19与糖尿病之间的联系方面仍然存在挑战。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 99 - 103
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引用次数: 0
Causal Evaluation of Pancreatitis in Children 儿童胰腺炎的病因评价
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69344
Fahmida Islam, Mst Naznin Sarker, Rafia Rashid, Farhana Islam, A S M Bazlul Karim
Pancreatitis in childhood is not common. It can be associated with severe morbidity and mortality. The role of clinicalevaluation is vital as it can be misdiagnosed easily. This study was aimed to review the prevalence, etiology,presentation and outcome of pancreatitis in children. This cross-sectional study was conducted at the Department ofPediatric Gastroenterology & Nutrition of Bangabandhu Sheikh Mujib Medical University, Dhaka from January,2017 through June, 2018. A total 43 cases of pancreatitis were included in this study. Pancreatitis was classified asacute pancreatitis(AP), acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) as per diagnostic criteriamade by INSPPIRE (International Study Group of Pediatric Pancreatitis: In Search for a Cure) group. Among 43children (age 10.1 mean ± 2.55,18 males); AP,14 (32.6%); ARP, 14(32.6%) and CP,15(34.8 %). Half of AP wasidiopathic. Majority of ARP (28.6%) were idiopathic and CP (40%) had calcific pancreatitis. Majority of patients hadvomiting followed by moderate to severe abdominal pain. In CP 4(26.6%) patient developed diabetes mellitus.Majority of pancreatitis in children is idiopathic. A sub-set of AP goes on to develop ARP and CP on follow-up andbeing in the idiopathic sub-set is a risk factor. CP is progress to endocrine and exocrine insufficiency. Early diagnosis,close monitoring and proper intervention are mandatory to reduce the potential morbidity and mortality. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):76-79
儿童胰腺炎并不常见。它可能与严重的发病率和死亡率有关。临床评估的作用是至关重要的,因为它很容易被误诊。本研究旨在回顾儿童胰腺炎的患病率、病因、表现和预后。这项横断面研究是在儿科消化内科进行的。2017年1月至2018年6月期间,孟加拉国谢赫穆吉布医科大学营养学。本研究共纳入43例胰腺炎病例。根据inspire(国际儿童胰腺炎研究组:In Search for a Cure)小组制定的诊断标准,将胰腺炎分为急性胰腺炎(AP)、急性复发性胰腺炎(ARP)和慢性胰腺炎(CP)。43例儿童(平均10.1岁±2.55岁,男性18例);美联社,14 (32.6%);ARP 14例(32.6%),CP 15例(34.8%)。一半的AP是特发性的。大多数ARP(28.6%)为特发性,CP(40%)为钙化性胰腺炎。大多数患者伴有呕吐,随后出现中度至重度腹痛。第4期(26.6%)患者并发糖尿病。大多数儿童胰腺炎是特发性的。AP的一个子集在随访中继续发展为ARP和CP,处于特发性子集是一个危险因素。CP进展为内分泌和外分泌功能不全。早期诊断、密切监测和适当干预是降低潜在发病率和死亡率的必要条件。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 76 - 79
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引用次数: 0
Effect of Slow Breathing Exercise on Time Domain Heart Rate Variability in Transfusion Dependent Thalassemic Patients 慢呼吸运动对输血依赖型地中海贫血患者时域心率变异性的影响
Pub Date : 2023-10-13 DOI: 10.3329/bsmmcj.v1i2.69338
Kamol Chandra Das, Sultana Ferdousi, S F H Urmi, Musfika Mostafa, Shomia Farid Tonni
Time domain measure of heart rate variability (HRV) is a newersystem to seek out any alteration in cardiacautonomic nerve function (CANF) in transfusion dependent thalassemic (TDT) patients. Slow breathing exercise(SBE) plays important role in improvement of HRV in health and various diseases.This research aims to observe theeffect of slow breathing exercise (SBE) on time domain measures of HRV in TDT patients. This prospectiveinterventional study was done in the Department of Physiology, Bangabandhu Sheikh Mujib Medical University(BSMMU), Dhaka in 2018 on 60 male TDT patients aged 15-30 years. Thirty patients received conventionaltreatment and 30 patients performed slow breathing exercise along with the conventional treatment for 3 months. Ageand sex matched healthy control were taken to compare. All subjects were followed up at baseline and after 3 months.Time domain HRV parameters were recorded by Power Lab 8/35. For statistical analysis paired sample 't' test andindependent sample 't' test were done. Mean RR interval, Mean SD, RMSSD and pRR50% were found significantlylower in TDT patients compared to healthy control at baseline and on the other hand mean heart rate was significantlyhigher in this group of patients. After 3 months of slow breathing exercise, significant decrement of mean heart rateand significant increment of others parameters occurred with trend of improvement in cardiac autonomic nervefunction in TDT patients. In conclusion slow breathing exercise may improve cardiac autonomic nerve function andsympathovagal balance in transfusion dependent thalassemic patients. Bangabandhu Sheikh Mujib Med. Coll. J. 2022;1(2):65-69
心率变异性时域测量(HRV)是一种寻找输血依赖性地中海贫血(TDT)患者心脏自主神经功能(CANF)改变的新系统。慢呼吸运动(SBE)在改善健康和各种疾病的HRV中起着重要的作用。本研究旨在观察慢呼吸运动(SBE)对TDT患者HRV时域测量的影响。这项前瞻性介入研究于2018年在达卡Bangabandhu Sheikh Mujib医科大学(BSMMU)生理学系进行,研究对象为60名年龄在15-30岁的男性TDT患者。30例患者接受常规治疗,30例患者在常规治疗的同时进行缓慢呼吸运动,为期3个月。选取年龄、性别匹配的健康对照进行比较。在基线和3个月后对所有受试者进行随访。时域HRV参数由Power Lab 8/35记录。统计分析采用配对样本t检验和独立样本t检验。TDT患者的平均RR间期、平均SD、RMSSD和pRR50%在基线时明显低于健康对照组,另一方面,该组患者的平均心率明显高于健康对照组。慢呼吸运动3个月后,TDT患者平均心率显著下降,其他参数显著升高,心脏自主神经功能有改善趋势。结论:慢呼吸运动可改善输血依赖性地中海贫血患者心脏自主神经功能和交感迷走神经平衡。Bangabandhu Sheikh Mujib Med. col。j . 2022; 1 (2): 65 - 69
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Bangabandhu Sheikh Mujib Medical University Journal
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