Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70757
G. Polevoy
Background: Great importance is paid to the physical development of school children, the positive influence of physical culture for the growth and development of children has been proven. At the same time, indicators in sports schools are falling due to insufficient development of physical qualities. The problem requires studying and improving the training process of athletes. The aim of the study: To increase the effectiveness of the training process of athletes aged 9-11 years due to the development of certain motor qualities. Study design: Pedagogical experiment. Research methods: The pedagogical experiment was conducted on the basis of the Olympic Reserve School number 1 (Kirov, Russia) from August to November 2022. The study involved children aged 9-11 years. 2 groups were formed: experimental and control consisting of 25 boys each. Classes were held 3 times a week. Children from the control group were engaged in the usual program, and children from the experimental group performed exercises to develop physical qualities. The complex was used for 10 weeks. Tests that were used in the study: Long jump from a place, Shuttle run 3 x 10m, Squats for 30 seconds, Hand strength, Leaning forward from a sitting position. Results: After the study, the experimental group was ahead of the control group in almost all indicators. In the long jump test, the difference between the experimental and control groups was 2.3cm (P<0.05). In the test, the shuttle run is 3x10m, the difference is 0.5 sec (P<0.05). In the “Squat for 30 seconds” test, the difference is 1.6 squats (P<0.05). In the test, the brush strength is 2 kg difference (P<0.05). There is no difference in the forward tilt test at the end of the experiment (P>0.05). Comparison of the results of the children of the control and experimental groups at the end of the pedagogical experiment indicates the superiority of the children of the experimental group. Thus, analyzing the results of testing the physical fitness of athletes aged 9-11, we can talk about the positive impact of the methodology proposed during the pedagogical experiment for the development of physical qualities of younger athletes. Conclusion: If a set of exercises aimed at developing physical qualities is purposefully applied in sports schools in working with children aged 9-11 years, then the indicators of children will improve significantly. This will increase the efficiency of the training process. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 246-253
{"title":"Development of physical qualities of athletes aged 9-11","authors":"G. Polevoy","doi":"10.3329/bjms.v23i1.70757","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70757","url":null,"abstract":"Background: Great importance is paid to the physical development of school children, the positive influence of physical culture for the growth and development of children has been proven. At the same time, indicators in sports schools are falling due to insufficient development of physical qualities. The problem requires studying and improving the training process of athletes. \u0000The aim of the study: To increase the effectiveness of the training process of athletes aged 9-11 years due to the development of certain motor qualities. \u0000Study design: Pedagogical experiment. \u0000Research methods: The pedagogical experiment was conducted on the basis of the Olympic Reserve School number 1 (Kirov, Russia) from August to November 2022. The study involved children aged 9-11 years. 2 groups were formed: experimental and control consisting of 25 boys each. Classes were held 3 times a week. Children from the control group were engaged in the usual program, and children from the experimental group performed exercises to develop physical qualities. The complex was used for 10 weeks. Tests that were used in the study: Long jump from a place, Shuttle run 3 x 10m, Squats for 30 seconds, Hand strength, Leaning forward from a sitting position. \u0000Results: After the study, the experimental group was ahead of the control group in almost all indicators. In the long jump test, the difference between the experimental and control groups was 2.3cm (P<0.05). In the test, the shuttle run is 3x10m, the difference is 0.5 sec (P<0.05). In the “Squat for 30 seconds” test, the difference is 1.6 squats (P<0.05). In the test, the brush strength is 2 kg difference (P<0.05). There is no difference in the forward tilt test at the end of the experiment (P>0.05). Comparison of the results of the children of the control and experimental groups at the end of the pedagogical experiment indicates the superiority of the children of the experimental group. Thus, analyzing the results of testing the physical fitness of athletes aged 9-11, we can talk about the positive impact of the methodology proposed during the pedagogical experiment for the development of physical qualities of younger athletes. \u0000Conclusion: If a set of exercises aimed at developing physical qualities is purposefully applied in sports schools in working with children aged 9-11 years, then the indicators of children will improve significantly. This will increase the efficiency of the training process. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 246-253","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"18 3","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Past research has demonstrated that a changed Sonic Hedgehog (SHH) pattern contributes to the development of colorectal cancer. This study’s objective was to determine whether the SHH gene’s promoter hypomethylation might be used to predict the likelihood of developing colorectal cancer. Methods: For the current investigation, 50 newly diagnosed and untreated colorectal cancer patients’ tumor samples and surrounding non-tumor tissues were gathered. SHH methylation was determined by methylation-specific PCR (MSP) and results correlated with several studied clinicopathological parameters. Results: Our results showed that SHH methylation levels are significantly present in normal tissues as compared to tumor tissues. Conclusion: We conclude SHH promoter is hypomethylated in colorectal cancers which may have an effect driving normal colon and rectum cells to cancer. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 200-206
{"title":"Hypomethylation of Sonic hedgehog in colorectal cancer","authors":"Maheera Teli, Madiha Niyaz, Gowhar Rashid, Ishrat Parveiz, R. Wani, Syed Mudassar","doi":"10.3329/bjms.v23i1.70719","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70719","url":null,"abstract":"Background: Past research has demonstrated that a changed Sonic Hedgehog (SHH) pattern contributes to the development of colorectal cancer. This study’s objective was to determine whether the SHH gene’s promoter hypomethylation might be used to predict the likelihood of developing colorectal cancer. \u0000Methods: For the current investigation, 50 newly diagnosed and untreated colorectal cancer patients’ tumor samples and surrounding non-tumor tissues were gathered. SHH methylation was determined by methylation-specific PCR (MSP) and results correlated with several studied clinicopathological parameters. \u0000Results: Our results showed that SHH methylation levels are significantly present in normal tissues as compared to tumor tissues. \u0000Conclusion: We conclude SHH promoter is hypomethylated in colorectal cancers which may have an effect driving normal colon and rectum cells to cancer. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 200-206","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":" 45","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139393576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70759
A. Alfawzan
Background: Proper diagnosis and treatment planning are the first steps in the management of pseudo-Class III malocclusion. Case Presentation: An 11 years old male patient with pseudo- class III malocclusion. Conclusion: A class I molar with average overjet and overbite was achieved with a sectional fixed orthodontic appliance. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 262-265
背景：正确的诊断和治疗计划是治疗假性 III 类错牙合畸形的第一步。病例介绍：一名 11 岁男性患者，患有假性 III 类错牙合畸形。结论通过分段固定矫正器，患者的臼齿达到了Ⅰ类，咬合和过咬合情况一般。孟加拉医学杂志》第 23 卷第 01 期 January'24 Page : 262-265
{"title":"Sectional Fixed Orthodontic Appliance for Management of a Pseudo Class III Malocclusion. Case Report","authors":"A. Alfawzan","doi":"10.3329/bjms.v23i1.70759","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70759","url":null,"abstract":"Background: Proper diagnosis and treatment planning are the first steps in the management of pseudo-Class III malocclusion. \u0000Case Presentation: An 11 years old male patient with pseudo- class III malocclusion. \u0000Conclusion: A class I molar with average overjet and overbite was achieved with a sectional fixed orthodontic appliance. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 262-265","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"132 4","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139395667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70710
Pham Van Truong, Pham Thi Ngoc An, Tran Quang Huy
Objective: This study aimed (1) to evaluate the internal consistency and test-retest reliability of the Vietnamese version of the Knowledge and Attitudes Survey Regarding Pain –revised questionnaire; and (2) to assess the relationship between the knowledge, attitudes and demographic factors in nurses. Materials and methods: A cross-sectional survey and a correlation research design was used to evaluate test-retest reliability. 154 participants were tested twice with a 2-week interval. Multivariate analysis was performed by using multiple linear regressions to test the relationship between demographic data with nurse’ knowledge and attitude of pain management. Results and Discussion: Reliability was confirmed by internal consistency (Cronbach α = 0.88) and test-retest reliability (intraclass correlation coefficient, 0.88). The results of multiple regression indicated that age, nurses had level 5, and nurses from internal medicine, ICU, emergency, obstetric, oncology department, those with previous education in pain management, and routinely assess pain for patients were predicted to KASRP score, accounting for 11.6%. Conclusion: The Vietnamese Knowledge and Attitudes Survey Regarding Pain- Revised questionnaire had satisfactory content validity and reliability for assessing pain management in nurses in Vietnam. Some demographic factors were predicted 11.6% of KASRP in Nurses. Further research need focus on those factors independently significant predicted to KASRP to improve nurse’s knowledge and attitude. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 160-170
{"title":"Reliability and validity of revised instrument on pain management and its relationship between knowledge and attitudes among nurses in Vietnam","authors":"Pham Van Truong, Pham Thi Ngoc An, Tran Quang Huy","doi":"10.3329/bjms.v23i1.70710","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70710","url":null,"abstract":"Objective: This study aimed (1) to evaluate the internal consistency and test-retest reliability of the Vietnamese version of the Knowledge and Attitudes Survey Regarding Pain –revised questionnaire; and (2) to assess the relationship between the knowledge, attitudes and demographic factors in nurses. \u0000Materials and methods: A cross-sectional survey and a correlation research design was used to evaluate test-retest reliability. 154 participants were tested twice with a 2-week interval. Multivariate analysis was performed by using multiple linear regressions to test the relationship between demographic data with nurse’ knowledge and attitude of pain management. \u0000Results and Discussion: Reliability was confirmed by internal consistency (Cronbach α = 0.88) and test-retest reliability (intraclass correlation coefficient, 0.88). The results of multiple regression indicated that age, nurses had level 5, and nurses from internal medicine, ICU, emergency, obstetric, oncology department, those with previous education in pain management, and routinely assess pain for patients were predicted to KASRP score, accounting for 11.6%. \u0000Conclusion: The Vietnamese Knowledge and Attitudes Survey Regarding Pain- Revised questionnaire had satisfactory content validity and reliability for assessing pain management in nurses in Vietnam. Some demographic factors were predicted 11.6% of KASRP in Nurses. Further research need focus on those factors independently significant predicted to KASRP to improve nurse’s knowledge and attitude. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 160-170","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"117 27","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139453719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70753
Uki Retno Budihastuti, Abdurahman Laqif, Eriana Melinawati, Teguh Prakosa, Hermawan Udiyanto, H. Priyanto, -. Darto, Affi Angelia Ratnasari, Asih Anggraeni, Agung Sari Wijayanti, Devi Cynthia Dewi, Kresto Atalyo De Hann
Background: Fallopian tube infertility results from sexually transmitted infections and pelvic inflammatory diseases. The most common causes of infertility in women are infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. These bacterial infections initiate an inflammatory reaction, and ongoing inflammation leads to scarring, obstructing the reproductive tract, and infertility. The pro-inflammatory cytokines IL-6 and TNF-α are involved in the inflammation response triggered by Chlamydia trachomatis and Neisseria gonorrhoeae infections. The study aimed to investigate the connection between the expression of IL-6 and TNF-α in patent and non-patent fallopian tubes. Methods: Analytical observational research with a cross-sectional approach. The 30 subjects were divided into two groups. Group I consisted of 15 subjects diagnosed with non-patent fallopian tubes, and group II consisted of 15 subjects diagnosed with patent fallopian tubes. Sampling technique using consecutive sampling. The research was conducted at Dr. Moewardi General Hospital from January to June 2022. Both groups were assessed based on age, BMI, parity, level of education, occupation, type of infertility, and expression of IL-6 and TNF-α. Results: The expression levels of IL-6 and TNF-α were compared between non-patent and patent fallopian tubes, with statistical analysis indicating a significant difference between the two groups. The p-value for IL-6 was 0.008, and the p-value for TNF-α was 0.030. Conclusion: There was a significant difference in IL-6 expression between the non-patent fallopian tube and the patent fallopian tube, with the IL-6 expression being higher in the non-patent fallopian tube than in the patent fallopian tube. Similarly, the expression of TNF-α on the non-patent fallopian tube and patent fallopian tube shows a higher expression of TNF-α on the non-patent fallopian tube than the patent fallopian tube. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 221-227
{"title":"Differences in expression of interleukin-6 and tumor necrosis factor-alpha fallopian tubes non-patent and fallopian tubes patent","authors":"Uki Retno Budihastuti, Abdurahman Laqif, Eriana Melinawati, Teguh Prakosa, Hermawan Udiyanto, H. Priyanto, -. Darto, Affi Angelia Ratnasari, Asih Anggraeni, Agung Sari Wijayanti, Devi Cynthia Dewi, Kresto Atalyo De Hann","doi":"10.3329/bjms.v23i1.70753","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70753","url":null,"abstract":"Background: Fallopian tube infertility results from sexually transmitted infections and pelvic inflammatory diseases. The most common causes of infertility in women are infections caused by Chlamydia trachomatis and Neisseria gonorrhoeae. These bacterial infections initiate an inflammatory reaction, and ongoing inflammation leads to scarring, obstructing the reproductive tract, and infertility. The pro-inflammatory cytokines IL-6 and TNF-α are involved in the inflammation response triggered by Chlamydia trachomatis and Neisseria gonorrhoeae infections. The study aimed to investigate the connection between the expression of IL-6 and TNF-α in patent and non-patent fallopian tubes. \u0000Methods: Analytical observational research with a cross-sectional approach. The 30 subjects were divided into two groups. Group I consisted of 15 subjects diagnosed with non-patent fallopian tubes, and group II consisted of 15 subjects diagnosed with patent fallopian tubes. Sampling technique using consecutive sampling. The research was conducted at Dr. Moewardi General Hospital from January to June 2022. Both groups were assessed based on age, BMI, parity, level of education, occupation, type of infertility, and expression of IL-6 and TNF-α. \u0000Results: The expression levels of IL-6 and TNF-α were compared between non-patent and patent fallopian tubes, with statistical analysis indicating a significant difference between the two groups. The p-value for IL-6 was 0.008, and the p-value for TNF-α was 0.030. \u0000Conclusion: There was a significant difference in IL-6 expression between the non-patent fallopian tube and the patent fallopian tube, with the IL-6 expression being higher in the non-patent fallopian tube than in the patent fallopian tube. Similarly, the expression of TNF-α on the non-patent fallopian tube and patent fallopian tube shows a higher expression of TNF-α on the non-patent fallopian tube than the patent fallopian tube. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 221-227","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"75 13","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139458369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70693
Alp Fethiye Yelkin, Gülşah G Arsalan, Dilek Özden, İ. Yılmaz, Büşra Ertuğrul, Seda Duztepeliler
Objective: The study was conducted with the aim of determining the readiness and acceptance levels and the clinical stress levels of students of a faculty of nursing for online learning in before, during and after clinical practice. Material and method: The descriptive research was executed with 233 students enrolled in the Faculty of Nursing in Izmir, in the western part of Turkey. The data was collected by means of Student Descriptive Characteristics Form,the Online Learning Readiness Scale (OLRS), the Online Learning Acceptance Scale (OLAS) and the Clinical Stress Questionnairre (CSQ). Number-percentage distribution, test/Mann Whitney-U/Kruskal Wallis analysis, Friedman variance analysis were used in the evaluation of the relevant data. Results: The difference between the three different measurements of the OLRS and OLAS were examined, and a statistically significant difference was found between them (X2=14.52, p<0.05; X2=35.02; p<0.05). The difference between the three different CSQ measurements was examined, and a statistically significant difference was found between them (X2=37.68; p<0.05). Conclusion: In conclusion, it was determined and identified that the readiness of the students for online learning and their acceptance levels show increase in the recurrent measurements and their stress levels with clinical practice reduces. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 95-101
{"title":"The Effect on Clinical Stress Levels of the Readiness and Acceptance Nursing Students Regarding the Online Learning Method Used in Professional Skills Practice","authors":"Alp Fethiye Yelkin, Gülşah G Arsalan, Dilek Özden, İ. Yılmaz, Büşra Ertuğrul, Seda Duztepeliler","doi":"10.3329/bjms.v23i1.70693","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70693","url":null,"abstract":"Objective: The study was conducted with the aim of determining the readiness and acceptance levels and the clinical stress levels of students of a faculty of nursing for online learning in before, during and after clinical practice. \u0000Material and method: The descriptive research was executed with 233 students enrolled in the Faculty of Nursing in Izmir, in the western part of Turkey. The data was collected by means of Student Descriptive Characteristics Form,the Online Learning Readiness Scale (OLRS), the Online Learning Acceptance Scale (OLAS) and the Clinical Stress Questionnairre (CSQ). Number-percentage distribution, test/Mann Whitney-U/Kruskal Wallis analysis, Friedman variance analysis were used in the evaluation of the relevant data. \u0000Results: The difference between the three different measurements of the OLRS and OLAS were examined, and a statistically significant difference was found between them (X2=14.52, p<0.05; X2=35.02; p<0.05). The difference between the three different CSQ measurements was examined, and a statistically significant difference was found between them (X2=37.68; p<0.05). \u0000Conclusion: In conclusion, it was determined and identified that the readiness of the students for online learning and their acceptance levels show increase in the recurrent measurements and their stress levels with clinical practice reduces. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 95-101","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":" 10","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139393189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70775
Soo Huat Teoh, Karen Christelle, Hui Zhu Thew, M. Sopian
In Malaysia, colorectal cancer is the second most common cause of cancer. Early detection through screening programmes is one of the most important public health initiatives in reducing cancer-related death. For decades, Malaysia has a colorectal cancer screening program in government-funded primary care facilities. However, screening uptake is minimal and numerous theories have been postulated. The aim of this article is to explore the possible reasons for low colorectal screening uptake among primary care physicians. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 278-280
{"title":"Colorectal cancer screening in Malaysia: a critical situation that must be addressed","authors":"Soo Huat Teoh, Karen Christelle, Hui Zhu Thew, M. Sopian","doi":"10.3329/bjms.v23i1.70775","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70775","url":null,"abstract":"In Malaysia, colorectal cancer is the second most common cause of cancer. Early detection through screening programmes is one of the most important public health initiatives in reducing cancer-related death. For decades, Malaysia has a colorectal cancer screening program in government-funded primary care facilities. However, screening uptake is minimal and numerous theories have been postulated. The aim of this article is to explore the possible reasons for low colorectal screening uptake among primary care physicians. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 278-280","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"75 6","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139396006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70679
Idaguko C. Anna, Awopetu P Ikuoyah, O. Ademola, I. O. Duru Francis
Objective: Studies have recognized the numerous health benefits of Chrysophyllum albidum. This study examine the phytochemical evaluation of ethanolic leaf extract of C. albidum and its histological effects on the beta-cells of streptozotocin-induced diabetic rats. Method: Forty-two Sprague-Dawley rats (170- 200 g) were divided into six (n=7) groups. Groups 1 and 2 were given 10 mL of normal saline; group 3 was given 2 mg/kg of glibenclamide; and groups 4, 5, and 6 were given 125, 250, and 500 mg/kg/ day of C. albidum ethanolic leaf extract, respectively. Except for group 1, animals in groups 2-6 were injected intraperitoneally with 50 mg/kg streptozotocin after 14 days of oral treatment with normal saline, glibenclamide, and extract. For the next 14 days, rats were given normal saline, glibenclamide, and extract. The rats were fasted overnight before sacrifice on day 14; the pancreas was removed under diethyl ether anaesthesia and prepared for histological examination using a modified aldehyde fuchsin staining technique. Standard procedures were used for phytochemical evaluation and proximate analysis. Results: It was observed histological that the pancreatic tissues revealed cellular regeneration of the damage beta cells at a doses of 250 and 500 mg/kg/day. Phytochemical screening revealed the following; anthocyanin, cardiac glycosides, alkaloids, flavonoids, phenols, terpenoids, reducing sugar, and tannins while proximate analysis confirmed that the leaf contained 4.83% moisture, 39.59% crude fibre, 3.35% ash, 2.35% crude fats, 3.21% crude proteins and 46.71% carbohydrate. Conclusion: The results shows that C. albidum may possess a strong pharmacological activity owing to its rich phyto- constituents. This may have mediated its antidiabetic action by pancreatic beta cells regeneration. Hence, C. albidum could be a potential drug precursor for management of diabetes. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 63-73
{"title":"Histomorphology of the Beta-Cells and Phytochemical Evaluation of Ethanolic Leaf Extract of Africa Star Apple - Chrysophyllum albidum (Sapotaceae)","authors":"Idaguko C. Anna, Awopetu P Ikuoyah, O. Ademola, I. O. Duru Francis","doi":"10.3329/bjms.v23i1.70679","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70679","url":null,"abstract":"Objective: Studies have recognized the numerous health benefits of Chrysophyllum albidum. This study examine the phytochemical evaluation of ethanolic leaf extract of C. albidum and its histological effects on the beta-cells of streptozotocin-induced diabetic rats. \u0000Method: Forty-two Sprague-Dawley rats (170- 200 g) were divided into six (n=7) groups. Groups 1 and 2 were given 10 mL of normal saline; group 3 was given 2 mg/kg of glibenclamide; and groups 4, 5, and 6 were given 125, 250, and 500 mg/kg/ day of C. albidum ethanolic leaf extract, respectively. Except for group 1, animals in groups 2-6 were injected intraperitoneally with 50 mg/kg streptozotocin after 14 days of oral treatment with normal saline, glibenclamide, and extract. For the next 14 days, rats were given normal saline, glibenclamide, and extract. The rats were fasted overnight before sacrifice on day 14; the pancreas was removed under diethyl ether anaesthesia and prepared for histological examination using a modified aldehyde fuchsin staining technique. Standard procedures were used for phytochemical evaluation and proximate analysis. \u0000Results: It was observed histological that the pancreatic tissues revealed cellular regeneration of the damage beta cells at a doses of 250 and 500 mg/kg/day. Phytochemical screening revealed the following; anthocyanin, cardiac glycosides, alkaloids, flavonoids, phenols, terpenoids, reducing sugar, and tannins while proximate analysis confirmed that the leaf contained 4.83% moisture, 39.59% crude fibre, 3.35% ash, 2.35% crude fats, 3.21% crude proteins and 46.71% carbohydrate. \u0000Conclusion: The results shows that C. albidum may possess a strong pharmacological activity owing to its rich phyto- constituents. This may have mediated its antidiabetic action by pancreatic beta cells regeneration. Hence, C. albidum could be a potential drug precursor for management of diabetes. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 63-73","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"6 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139394270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70707
Bhoraniya Abdullah Ismail, M. Nawab, S. H. Fatima
Background: Pityriasis Versicolor (PV) is a chronic superficial fungal infection of skin caused by lipophilic yeast Malassezia species. Its prevalence, predisposing factors and clinical presentations varies in different geographical locations around the world. Despite being a common disease, its diagnosis and treatment remain a challenge. The aim of this study was to document the clinico-epidemiological characteristics of the participants diagnosed with PV. Materials and Methods: A descriptive crosssectional study was carried out on 104 consecutive participants attending the Outpatient Department of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad during 1st July, 2020 and 31stJuly, 2021. Their demographic data, risk factors, clinical features, and temperament were recorded in the case record form. The participants were diagnosed clinically and confirmed by direct microscopy. The data were analysed retrospectively. Results: In this study, 75 participants (72%) were males and the ratio of male to female was 2.6:1. The most frequently affected participants were in 20–40 years of age group. The mean age was 29.14 (±10.52) years. PV was present in 28.8% students, 21.15% workers, 31.7% employees, 11.5% housewives and 6.7% businessmen. The most common affected site was back followed by neck and chest. PV was found prone to the Fitzpatrick skin types 4 (49.03%) and 3 (27.8%). Hypo-pigmented lesions were more common.The Malassezia species was present in multiple lesions of all the participants. Conclusions: This study documented the clinico-epidemiological profile of PV. The findings of this study may provide us current understanding of PV in India. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 141-149
{"title":"A Single Centre Demographic and Clinico-epidemiological Profile of Pityriasis Versicolor in Adults: A Cross-Sectional Study","authors":"Bhoraniya Abdullah Ismail, M. Nawab, S. H. Fatima","doi":"10.3329/bjms.v23i1.70707","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70707","url":null,"abstract":"Background: Pityriasis Versicolor (PV) is a chronic superficial fungal infection of skin caused by lipophilic yeast Malassezia species. Its prevalence, predisposing factors and clinical presentations varies in different geographical locations around the world. Despite being a common disease, its diagnosis and treatment remain a challenge. The aim of this study was to document the clinico-epidemiological characteristics of the participants diagnosed with PV. \u0000Materials and Methods: A descriptive crosssectional study was carried out on 104 consecutive participants attending the Outpatient Department of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad during 1st July, 2020 and 31stJuly, 2021. Their demographic data, risk factors, clinical features, and temperament were recorded in the case record form. The participants were diagnosed clinically and confirmed by direct microscopy. The data were analysed retrospectively. \u0000Results: In this study, 75 participants (72%) were males and the ratio of male to female was 2.6:1. The most frequently affected participants were in 20–40 years of age group. The mean age was 29.14 (±10.52) years. PV was present in 28.8% students, 21.15% workers, 31.7% employees, 11.5% housewives and 6.7% businessmen. The most common affected site was back followed by neck and chest. PV was found prone to the Fitzpatrick skin types 4 (49.03%) and 3 (27.8%). Hypo-pigmented lesions were more common.The Malassezia species was present in multiple lesions of all the participants. \u0000Conclusions: This study documented the clinico-epidemiological profile of PV. The findings of this study may provide us current understanding of PV in India. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 141-149","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"28 14","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139456046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-01DOI: 10.3329/bjms.v23i1.70708
Esin Çeber Turfan, Meryem Özdemir, Nazlı Ünlü Bıdık
Objective: The aim of this study is to examine the experiences of midwives working in the maternity ward during the COVID-19 pandemic by SWOT analysis. Materials and Methods: A descriptive qualitative study reported following the COREQ guidelines. For the purposes of this study, 40 midwives working in the delivery room throughout the pandemic were interviewed. Research data were collected using a Personal Information Form (PIF) and a SWOT analysis interview form. One-on-one and indepth telephone interviews were conducted with the midwives. All interviews were recorded with the consent of the midwives. Collected data were transcribed and a content analysis was carried out using the MAQDA 2020 program. Results: Data collected in the study were categorized under four main themes as “Strengths”, “Weaknesses”, “Opportunities” and “Threats”. Conclusion: Midwives worked under difficult conditions during pandemi, so they were extremely tired and worn out. Midwives who could not go home during this difficult period gave psychological warfare because they were separated from their families. In addition, they thought that they could not provide adequate care and support to pregnant women at the time of delivery within the framework of social distance protection measures. This made them feel professionally inadequate. Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 150-159
{"title":"SWOT Analysis on The Views of Midwives Assigned in The Delivery Room About The Effects of The Covid-19 Pandemic: A Qualitative Study","authors":"Esin Çeber Turfan, Meryem Özdemir, Nazlı Ünlü Bıdık","doi":"10.3329/bjms.v23i1.70708","DOIUrl":"https://doi.org/10.3329/bjms.v23i1.70708","url":null,"abstract":"Objective: The aim of this study is to examine the experiences of midwives working in the maternity ward during the COVID-19 pandemic by SWOT analysis. \u0000Materials and Methods: A descriptive qualitative study reported following the COREQ guidelines. For the purposes of this study, 40 midwives working in the delivery room throughout the pandemic were interviewed. Research data were collected using a Personal Information Form (PIF) and a SWOT analysis interview form. One-on-one and indepth telephone interviews were conducted with the midwives. All interviews were recorded with the consent of the midwives. Collected data were transcribed and a content analysis was carried out using the MAQDA 2020 program. \u0000Results: Data collected in the study were categorized under four main themes as “Strengths”, “Weaknesses”, “Opportunities” and “Threats”. \u0000Conclusion: Midwives worked under difficult conditions during pandemi, so they were extremely tired and worn out. Midwives who could not go home during this difficult period gave psychological warfare because they were separated from their families. In addition, they thought that they could not provide adequate care and support to pregnant women at the time of delivery within the framework of social distance protection measures. This made them feel professionally inadequate. \u0000Bangladesh Journal of Medical Science Vol. 23 No. 01 January’24 Page : 150-159","PeriodicalId":8696,"journal":{"name":"Bangladesh Journal of Medical Science","volume":"51 9","pages":""},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139394815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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