Pub Date : 2025-10-07DOI: 10.1016/j.bse.2025.105147
Guy Paulin M. Kemayou , Ya-shi Wang , Wen-Chao Zhou , Gervais M. Happi , Shi-qi Liu , Wei Su , Bin Li , Simeon F. Kouam , Wei Wang , Yu-pei Yang
A phytochemical investigation of Kadsura coccinea fruits resulted in the isolation of twenty-eight secondary metabolites, including twenty-four lignans (1−24), a triterpenoid (25), a steroid (26), a shikimic acid (27), and a furan derivative (28). The structures of these compounds were identified using extensive spectroscopic methods, as well as comparison with literature data. To the best of our knowledge, compounds 9, 13−15, 21, and 25−28 were newly isolated from Kadsura coccinea, and compounds 14, 27, and 28 were isolated from the genus Kadsura for the first time. All the isolated compounds were evaluated for their hepatoprotective activity against APAP-induced toxicity in HepG-2 cells. Kadsuphilol A (1) showed significant hepatoprotective activity, with a cell survival rate of 60.7 ± 1.5 % at 20 μM (positive control, bicyclol, 60.4 ± 1.6 %). The lignans (2−17) exhibited moderate activity, with cell survival rates ranging from 49.3 ± 1.0 % to 56.5 ± 0.9 %. The structure-activity relationship of the tested compounds was investigated, and their chemotaxonomic significance was also discussed.
{"title":"Hepatoprotective compounds from fruits of Kadsura coccinea (Lem.) A. C. Smith (Schisandraceae) and their chemotaxonomic significance","authors":"Guy Paulin M. Kemayou , Ya-shi Wang , Wen-Chao Zhou , Gervais M. Happi , Shi-qi Liu , Wei Su , Bin Li , Simeon F. Kouam , Wei Wang , Yu-pei Yang","doi":"10.1016/j.bse.2025.105147","DOIUrl":"10.1016/j.bse.2025.105147","url":null,"abstract":"<div><div>A phytochemical investigation of <em>Kadsura coccinea</em> fruits resulted in the isolation of twenty-eight secondary metabolites, including twenty-four lignans (<strong>1−24</strong>), a triterpenoid (<strong>25</strong>), a steroid (<strong>26</strong>), a shikimic acid (<strong>27</strong>), and a furan derivative (<strong>28</strong>). The structures of these compounds were identified using extensive spectroscopic methods, as well as comparison with literature data. To the best of our knowledge, compounds <strong>9</strong>, <strong>13−15</strong>, <strong>21</strong>, and <strong>25−28</strong> were newly isolated from <em>Kadsura coccinea</em>, and compounds <strong>14</strong>, <strong>27,</strong> and <strong>28</strong> were isolated from the genus <em>Kadsura</em> for the first time. All the isolated compounds were evaluated for their hepatoprotective activity against APAP-induced toxicity in HepG-2 cells. Kadsuphilol A (<strong>1</strong>) showed significant hepatoprotective activity, with a cell survival rate of 60.7 ± 1.5 % at 20 μM (positive control, bicyclol, 60.4 ± 1.6 %). The lignans (<strong>2−17</strong>) exhibited moderate activity, with cell survival rates ranging from 49.3 ± 1.0 % to 56.5 ± 0.9 %. The structure-activity relationship of the tested compounds was investigated, and their chemotaxonomic significance was also discussed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105147"},"PeriodicalIF":2.0,"publicationDate":"2025-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145262930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-10-04DOI: 10.1016/j.bse.2025.105148
Yacov Kilsztajn , Leonardo Regnier de Lima Pereira , Marcelo Tomé Kubo , Antonio Salatino , Maria Luiza Faria Salatino
This study explores the composition, taxonomic significance, and evolutionary history of seed fatty acid (FA) profiles in Campomanesia (Myrtaceae), a South American genus comprising approximately 45 species. Seed oils from six Campomanesia species were analyzed using gas chromatography and mass spectrometry. FA-based clustering was then compared with molecular phylogeny derived from nuclear and plastid markers, with Psidium guajava and Feijoa sellowiana included as outgroups. The results revealed a high degree of congruence between FA composition and phylogenetic relationships, as well as species-specific FA profiles that were consistent across individuals from different populations, highlighting their potential as reliable taxonomic markers. While P. guajava and F. sellowiana exhibited high linoleic acid content, Campomanesia species presented more balanced proportions of saturated and monounsaturated FA. Ancestral state reconstructions indicated a consistent evolutionary trend toward reduced proportions of unsaturated FA within Campomanesia. Although correlations with climatic variables such as temperature and precipitation were weak and statistically non-significant, a strong phylogenetic signal was detected. These findings suggest that genetic drift, rather than climate-driven selection, may have played a dominant role in shaping FA profiles, reinforcing their potential utility in taxonomic studies of the genus.
{"title":"Insights into the evolution and taxonomic meaning of seed fatty acid profiles in Campomanesia (Myrtaceae)","authors":"Yacov Kilsztajn , Leonardo Regnier de Lima Pereira , Marcelo Tomé Kubo , Antonio Salatino , Maria Luiza Faria Salatino","doi":"10.1016/j.bse.2025.105148","DOIUrl":"10.1016/j.bse.2025.105148","url":null,"abstract":"<div><div>This study explores the composition, taxonomic significance, and evolutionary history of seed fatty acid (FA) profiles in <em>Campomanesia</em> (Myrtaceae), a South American genus comprising approximately 45 species. Seed oils from six <em>Campomanesia</em> species were analyzed using gas chromatography and mass spectrometry. FA-based clustering was then compared with molecular phylogeny derived from nuclear and plastid markers, with <em>Psidium guajava</em> and <em>Feijoa sellowiana</em> included as outgroups. The results revealed a high degree of congruence between FA composition and phylogenetic relationships, as well as species-specific FA profiles that were consistent across individuals from different populations, highlighting their potential as reliable taxonomic markers. While <em>P. guajava</em> and <em>F. sellowiana</em> exhibited high linoleic acid content, <em>Campomanesia</em> species presented more balanced proportions of saturated and monounsaturated FA. Ancestral state reconstructions indicated a consistent evolutionary trend toward reduced proportions of unsaturated FA within <em>Campomanesia</em>. Although correlations with climatic variables such as temperature and precipitation were weak and statistically non-significant, a strong phylogenetic signal was detected. These findings suggest that genetic drift, rather than climate-driven selection, may have played a dominant role in shaping FA profiles, reinforcing their potential utility in taxonomic studies of the genus.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105148"},"PeriodicalIF":2.0,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145217442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The phytochemical investigation on the aerial parts of Hypericum lancasteri led to the isolation and characterization of eight sesquiterpenoids, including an undescribed one belonging to guaiane-type (1) and seven known sesquiterpenoids (2–7). The structure of the new compound was elucidated by spectroscopic techniques, including 1D-/2D-NMR spectroscopy and HR-ESI-MS analysis. The known compounds were identified by comparison of their observed physicochemical properties and spectroscopic data with those reported in the literature. Notably, all isolated sesquiterpenoids were obtained from H. lancasteri for the first time, and compounds 1–6 and 8 are reported here for the first time in the family Hypericaceae. The taxonomic significance of these isolated sesquiterpenoids was discussed, contributing to a broader understanding of the chemotaxonomic classification within the family Hypericaceae.
{"title":"Sesquiterpenoids from the aerial parts of Hypericum lancasteri (Hypericaceae) and their chemotaxonomic significance","authors":"Qi Zhou , Jiang Wan , Chun-Xiao Jiang , Shou-Yuan Wu , Peng-Jun Zhou , Ying-Peng Tong","doi":"10.1016/j.bse.2025.105145","DOIUrl":"10.1016/j.bse.2025.105145","url":null,"abstract":"<div><div>The phytochemical investigation on the aerial parts of <em>Hypericum lancasteri</em> led to the isolation and characterization of eight sesquiterpenoids, including an undescribed one belonging to guaiane-type (<strong>1</strong>) and seven known sesquiterpenoids (<strong>2</strong>–<strong>7</strong>). The structure of the new compound was elucidated by spectroscopic techniques, including 1D-/2D-NMR spectroscopy and HR-ESI-MS analysis. The known compounds were identified by comparison of their observed physicochemical properties and spectroscopic data with those reported in the literature. Notably, all isolated sesquiterpenoids were obtained from <em>H. lancasteri</em> for the first time, and compounds <strong>1</strong>–<strong>6</strong> and <strong>8</strong> are reported here for the first time in the family Hypericaceae. The taxonomic significance of these isolated sesquiterpenoids was discussed, contributing to a broader understanding of the chemotaxonomic classification within the family Hypericaceae.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105145"},"PeriodicalIF":2.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145227419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-26DOI: 10.1016/j.bse.2025.105142
Lei Zeng , Yingle Chen , Wei Wei , Song Wang , Liu Yang , Qiaoguang Li , Zhihong Wang
This study investigates the antibacterial potential of extracts from the two different varieties of Ardisia mamillata Hance, a plant known for its medicinal value and natural adaptation to damp, fungal-prone environments. Although widely appreciated for its ornamental and traditional therapeutic uses, its antimicrobial activity remains underexplored. Extracts were prepared from red-leaf (Am_red) and green-leaf (Am_green) variants and tested against two phytopathogenic fungi: Fusarium and Botrytis cinerea. Both variants exhibited antifungal activity, with Am_red extracts showing superior efficacy—achieving a 33.4 % higher average inhibition rate compared to Am_green. In particular, Am_red extracts demonstrated strong inhibition against B. cinerea, with an average inhibition rate of 87.23 %.
UPLC-MS/MS analysis revealed that the dominant chemical classes in both extract types were flavonoids, lipids, amino acids and derivatives, alkaloids, phenolic acids, and organic acids—comprising 86.32 % in Am_red and 85.56 % in Am_green. Several bioactive compounds were identified, including petunidin-3-O-glucoside, calycosin, hispidulin, vanillic acid, and syringic acid. The preliminary data suggests that flavonoids, phenolic acids, and alkaloids are the key contributors to the antibacterial properties observed. The findings highlight the potential of A. mamillata Hance, particularly its red-leaf form, as a source of natural antimicrobial agents for sustainable applications in plant protection and phytopathogen control.
本研究研究了两种不同品种紫荆（Ardisia mamillata Hance）提取物的抗菌潜力，这种植物以其药用价值和对潮湿、真菌易发环境的天然适应性而闻名。虽然其观赏和传统治疗用途广受赞赏，但其抗菌活性仍未得到充分开发。从红叶（Am_red）和绿叶（Am_green）变体中提取提取物，并对两种植物病原真菌镰刀菌（Fusarium）和灰霉病菌（Botrytis cinerea）进行了抗性试验。两种变体均表现出抗真菌活性，其中Am_red提取物表现出更好的效果，平均抑制率比Am_green高33.4%。其中，Am_red提取物对灰霉病芽孢杆菌具有较强的抑制作用，平均抑制率为87.23%。UPLC-MS/MS分析表明，两种提取物的主要化学成分为黄酮类、脂类、氨基酸及其衍生物、生物碱、酚酸和有机酸，分别占Am_red和Am_green的86.32%和85.56%。鉴定出几种生物活性化合物，包括牵牛花苷-3- o -葡萄糖苷、毛蕊异黄酮、海鞘苷、香草酸和丁香酸。初步数据表明，黄酮类化合物、酚酸和生物碱是其抗菌性能的主要贡献者。这些发现突出了a . mamillata Hance的潜力，特别是其红叶形式，作为天然抗菌剂的来源，在植物保护和植物病原体控制方面具有可持续的应用。
{"title":"Correlation between antibacterial activity and compound composition of Ardisia mamillata Hance extract","authors":"Lei Zeng , Yingle Chen , Wei Wei , Song Wang , Liu Yang , Qiaoguang Li , Zhihong Wang","doi":"10.1016/j.bse.2025.105142","DOIUrl":"10.1016/j.bse.2025.105142","url":null,"abstract":"<div><div>This study investigates the antibacterial potential of extracts from the two different varieties of <em>Ardisia mamillata Hance</em>, a plant known for its medicinal value and natural adaptation to damp, fungal-prone environments. Although widely appreciated for its ornamental and traditional therapeutic uses, its antimicrobial activity remains underexplored. Extracts were prepared from red-leaf (Am_red) and green-leaf (Am_green) variants and tested against two phytopathogenic fungi: <em>Fusarium</em> and <em>Botrytis cinerea</em>. Both variants exhibited antifungal activity, with Am_red extracts showing superior efficacy—achieving a 33.4 % higher average inhibition rate compared to Am_green. In particular, Am_red extracts demonstrated strong inhibition against <em>B. cinerea</em>, with an average inhibition rate of 87.23 %.</div><div>UPLC-MS/MS analysis revealed that the dominant chemical classes in both extract types were flavonoids, lipids, amino acids and derivatives, alkaloids, phenolic acids, and organic acids—comprising 86.32 % in Am_red and 85.56 % in Am_green. Several bioactive compounds were identified, including petunidin-3-O-glucoside, calycosin, hispidulin, vanillic acid, and syringic acid. The preliminary data suggests that flavonoids, phenolic acids, and alkaloids are the key contributors to the antibacterial properties observed. The findings highlight the potential of <em>A. mamillata Hance</em>, particularly its red-leaf form, as a source of natural antimicrobial agents for sustainable applications in plant protection and phytopathogen control.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105142"},"PeriodicalIF":2.0,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145155780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-23DOI: 10.1016/j.bse.2025.105143
Yan Piao , Ze Wu , Yue Zhang, Qiong Wu, Jinglin Piao, Mengwei Gao, Fang Ye, Changhao Zhang, Lili Jin
A total of 18 compounds were isolated from whole Parasenecio auriculatus (DC.) H. Koyama plants, including eleven flavonoids (1–11), four mono-phenols (12–15), one triterpenoid (16), one coumarin (17), and one sterol (18). The chemical structures of these compounds were determined via nuclear magnetic resonance spectroscopy and mass spectrometry, then compared with published chemical structural data. All compounds were isolated from P. auriculatus for the first time, while compounds 4, 5, 7 and 10 were isolated from a species in the genus Parasenecio for the first time. The chemotaxonomic significance of these compounds is discussed.
{"title":"Chemical constituents of Parasenecio auriculatus (DC.) H. koyama and their chemotaxonomic significance","authors":"Yan Piao , Ze Wu , Yue Zhang, Qiong Wu, Jinglin Piao, Mengwei Gao, Fang Ye, Changhao Zhang, Lili Jin","doi":"10.1016/j.bse.2025.105143","DOIUrl":"10.1016/j.bse.2025.105143","url":null,"abstract":"<div><div>A total of 18 compounds were isolated from whole <em>Parasenecio auriculatus</em> (DC.) H. Koyama plants, including eleven flavonoids (<strong>1</strong>–<strong>11</strong>), four mono-phenols (<strong>12</strong>–<strong>15</strong>), one triterpenoid (<strong>16</strong>), one coumarin (<strong>17</strong>), and one sterol (<strong>18</strong>). The chemical structures of these compounds were determined via nuclear magnetic resonance spectroscopy and mass spectrometry, then compared with published chemical structural data. All compounds were isolated from <em>P</em>. <em>auriculatus</em> for the first time, while compounds <strong>4</strong>, <strong>5</strong>, <strong>7</strong> and <strong>10</strong> were isolated from a species in the genus <em>Parasenecio</em> for the first time. The chemotaxonomic significance of these compounds is discussed.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105143"},"PeriodicalIF":2.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-22DOI: 10.1016/j.bse.2025.105144
Zhen-Xiang Liu , Lin-Fen Ding , Ye-Ting Shi , Zhou Liu , Shi-Huan Yin , Qiu-Ye Zhao , Liu-Dong Song , Xing-De Wu
A phytochemical investigation of Illicium henryi fruits resulted in the identification of 31 compounds, including fourteen sesquiterpenoids (1–14), two flavonoids (15–16), seven lignans (17–23), one shikimic acid derivative (24), one phenylpropanoid derivative (25), two phenolic compounds (26 and 27), three monoterpenoids (28–30), and one C13 norsesquiterpenoid (31). The structures of these compounds were elucidated through 1H and 13C NMR spectroscopic analyses and comparison with previously documented data. Twenty compounds (2–4, 8, 9, 14, 15, 17–19, 21, and 23–31) were isolated from I. henryi for the first time, and among them, eleven compounds (15, 17–19, 23, 25–28, 30, and 31) had never been previously isolated from any Illicium species. Additionally, this article discusses the chemotaxonomic significance of these compounds.
{"title":"Chemical constituents from the fruits of Illicium henryi Diels and their chemotaxonomic significance","authors":"Zhen-Xiang Liu , Lin-Fen Ding , Ye-Ting Shi , Zhou Liu , Shi-Huan Yin , Qiu-Ye Zhao , Liu-Dong Song , Xing-De Wu","doi":"10.1016/j.bse.2025.105144","DOIUrl":"10.1016/j.bse.2025.105144","url":null,"abstract":"<div><div>A phytochemical investigation of <em>Illicium henryi</em> fruits resulted in the identification of 31 compounds, including fourteen sesquiterpenoids (<strong>1</strong>–<strong>14</strong>), two flavonoids (<strong>15</strong>–<strong>16</strong>), seven lignans (<strong>17</strong>–<strong>23</strong>), one shikimic acid derivative (<strong>24</strong>), one phenylpropanoid derivative (<strong>25</strong>), two phenolic compounds (<strong>26</strong> and <strong>27</strong>), three monoterpenoids (<strong>28</strong>–<strong>30</strong>), and one C13 norsesquiterpenoid (<strong>31</strong>). The structures of these compounds were elucidated through <sup>1</sup>H and <sup>13</sup>C NMR spectroscopic analyses and comparison with previously documented data. Twenty compounds (<strong>2</strong>–<strong>4</strong>, <strong>8</strong>, <strong>9</strong>, <strong>14</strong>, <strong>15</strong>, <strong>17</strong>–<strong>19</strong>, <strong>21</strong>, and <strong>23</strong>–<strong>31</strong>) were isolated from <em>I. henryi</em> for the first time, and among them, eleven compounds (<strong>15</strong>, <strong>17</strong>–<strong>19</strong>, <strong>23</strong>, <strong>25</strong>–<strong>28</strong>, <strong>30</strong>, and <strong>31</strong>) had never been previously isolated from any <em>Illicium</em> species. Additionally, this article discusses the chemotaxonomic significance of these compounds.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105144"},"PeriodicalIF":2.0,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-21DOI: 10.1016/j.bse.2025.105137
Erika Elias da Silva, Luan Danilo Ferreira de Andrade Melo, João Luciano de Andrade Melo Junior, Larice Bruna Ferreira Soares, Vilma Marques Ferreira, Keven Willian Sarmento Galdino da Silva, Marcus Gabriel de Carvalho Ramos
The invasive species Leucaena leucocephala (leucaena) negatively impacts ecosystems, requiring sustainable control strategies. This study evaluated the allelopathic effects of plant extracts from Eucalyptus staigeriana, Corymbia citriodora, Eucalyptus globulus, Schinus terebinthifolius, Copaifera officinalis, and pyroligneous extract on the germination and early development of L. leucocephala. Essential oils were tested at concentrations of 0.2; 0.4; 0.6; 0.8; 1.0 and 1.2 % (v v−1), while the pyroligneous extract was diluted at 1:100 (v v−1), using the same concentrations of essential oils, with the control (0 %), immersed in distilled water, only. Germination and morphological parameters were analyzed using principal component analysis. All extracts inhibited leucaena germination and growth, with efficiency dependent on concentration. The essential oils of E. staigeriana and C. citriodora were most effective at 1.2 %, while E. globulus performed best at 0.8 and 1.0 %. S. terebinthifolius significantly inhibited germination at all concentrations, whereas C. officinalis essential oil and pyroligneous extract showed optimal results at 1.0 and 1.2 %. The study confirms that plant extracts are viable bioherbicides for controlling L. leucocephala.
{"title":"Effect of allelopathic plant extracts on Leucaena leucocephala (Lam.) de Wit seeds: a multivariate and machine learning approach to a global problem","authors":"Erika Elias da Silva, Luan Danilo Ferreira de Andrade Melo, João Luciano de Andrade Melo Junior, Larice Bruna Ferreira Soares, Vilma Marques Ferreira, Keven Willian Sarmento Galdino da Silva, Marcus Gabriel de Carvalho Ramos","doi":"10.1016/j.bse.2025.105137","DOIUrl":"10.1016/j.bse.2025.105137","url":null,"abstract":"<div><div>The invasive species <em>Leucaena leucocephala</em> (leucaena) negatively impacts ecosystems, requiring sustainable control strategies. This study evaluated the allelopathic effects of plant extracts from <em>Eucalyptus staigeriana</em>, <em>Corymbia citriodora</em>, <em>Eucalyptus globulus</em>, <em>Schinus terebinthifolius</em>, <em>Copaifera officinalis</em>, and pyroligneous extract on the germination and early development of <em>L. leucocephala</em>. Essential oils were tested at concentrations of 0.2; 0.4; 0.6; 0.8; 1.0 and 1.2 % (v v<sup>−1</sup>), while the pyroligneous extract was diluted at 1:100 (v v<sup>−1</sup>), using the same concentrations of essential oils, with the control (0 %), immersed in distilled water, only. Germination and morphological parameters were analyzed using principal component analysis. All extracts inhibited leucaena germination and growth, with efficiency dependent on concentration. The essential oils of <em>E. staigeriana</em> and <em>C. citriodora</em> were most effective at 1.2 %, while <em>E. globulus</em> performed best at 0.8 and 1.0 %. <em>S. terebinthifolius</em> significantly inhibited germination at all concentrations, whereas <em>C. officinalis</em> essential oil and pyroligneous extract showed optimal results at 1.0 and 1.2 %. The study confirms that plant extracts are viable bioherbicides for controlling <em>L. leucocephala</em>.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105137"},"PeriodicalIF":2.0,"publicationDate":"2025-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-20DOI: 10.1016/j.bse.2025.105138
Onome M. Adeboye , Fazila Zulfiqar , Abimbola Sowemimo , Margaret Sofidiya , Ikhlas A. Khan , Zulfiqar Ali
Plants of the Culcasia genus have long been used by traditional healers to treat various ailments since ancient times. Ethnomedicinal studies highlight their application in alleviating pain and inflammation, combating cancer, and even in pregnancy detection. Among them, Culcasia parviflora N.E.Br. (family Araceae) is traditionally used in Africa for pain and inflammation relief, although its chemical constituents remain largely unexplored. In this study, eight compounds, including megastigmanes and indoles, were isolated from a 95 % ethanol extract of C. parviflora leaves. Structural elucidation was carried out using one- and two-dimensional NMR spectroscopy, with the results compared against previously reported data. This work details the isolation and structural characterization of these compounds and discusses their chemotaxonomic relevance.
{"title":"Megastigmanes and indoles from Culcasia parviflora (Araceae)","authors":"Onome M. Adeboye , Fazila Zulfiqar , Abimbola Sowemimo , Margaret Sofidiya , Ikhlas A. Khan , Zulfiqar Ali","doi":"10.1016/j.bse.2025.105138","DOIUrl":"10.1016/j.bse.2025.105138","url":null,"abstract":"<div><div>Plants of the <em>Culcasia</em> genus have long been used by traditional healers to treat various ailments since ancient times. Ethnomedicinal studies highlight their application in alleviating pain and inflammation, combating cancer, and even in pregnancy detection. Among them, <em>Culcasia parviflora</em> N.E.Br. (family Araceae) is traditionally used in Africa for pain and inflammation relief, although its chemical constituents remain largely unexplored. In this study, eight compounds, including megastigmanes and indoles, were isolated from a 95 % ethanol extract of <em>C. parviflora</em> leaves. Structural elucidation was carried out using one- and two-dimensional NMR spectroscopy, with the results compared against previously reported data. This work details the isolation and structural characterization of these compounds and discusses their chemotaxonomic relevance.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105138"},"PeriodicalIF":2.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Curcuma species belonging to the Zingiberaceae family has been widely known for its beneficial effects on human health. Three species of Curcuma, Curcuma longa L., Curcuma xanthorrhiza, and Curcuma manga, have been utilized because of their biological and pharmacological activities. Different origins truly affected the metabolite compositions of Curcuma species, thus affecting the biological effects. This research aimed to apply a non-targeted metabolomics approach utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS) incorporated with chemometrics of principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) for identification of global metabolomics profiles and discrimination of C. longa L., C. xanthorrhiza, and C. manga from different origins. Species and origin-based variations in metabolite composition were clearly visualized through PCA and PLS-DA score plots. Key discriminating metabolites, such as curcumin and (+)-nootkatone, were identified using variable importance in projection (VIP) values, confirming their role in distinguishing among species and origins. These findings suggest that environmental factors significantly influence the metabolic profiles of Curcuma species. In conclusion, this study highlights the potential of LC-HRMS-based non-targeted metabolomics combined with chemometric analysis as a reliable tool for the authentication, classification, and quality control of Curcuma species, supporting their safe and standardized use in pharmaceutical and nutraceutical applications.
姜黄属姜科植物，因其对人体健康的有益作用而广为人知。姜黄（Curcuma longa L.）、姜黄（Curcuma xanthorrhiza）和姜黄（Curcuma manga）三种姜黄因其生物和药理活性而被广泛利用。不同的来源确实影响了姜黄的代谢物组成，从而影响了姜黄的生物学效应。本研究旨在应用非靶向代谢组学方法，利用液相色谱-高分辨率质谱（LC-HRMS）结合主成分分析（PCA）和偏最小二乘判别分析（PLS-DA）的化学计量学方法鉴定全球代谢组学特征，并对不同来源的龙葵、黄腐根和日本龙葵进行区分。通过PCA和PLS-DA评分图清晰地显示了代谢物组成的物种和来源差异。关键的鉴别代谢物，如姜黄素和(+)-诺卡酮，使用可变重要投影（VIP）值进行鉴定，确认了它们在物种和起源区分中的作用。这些结果表明，环境因素显著影响姜黄的代谢谱。总之，本研究强调了基于lc - hrms的非靶向代谢组学与化学计量学分析相结合作为姜黄鉴别、分类和质量控制的可靠工具的潜力，支持其在制药和营养保健应用中的安全和标准化使用。
{"title":"Non-targeted metabolomics analysis of Curcuma rhizomes species from different origins using LC-orbitrap HRMS combined with chemometrics","authors":"Ayu Septi Anggraeni , Anjar Windarsih , Hendy Dwi Warmiko , Abdul Rohman , Suratno , Anita Agustina Styawan , Ani Widarti","doi":"10.1016/j.bse.2025.105140","DOIUrl":"10.1016/j.bse.2025.105140","url":null,"abstract":"<div><div><em>Curcuma</em> species belonging to the <em>Zingiberaceae</em> family has been widely known for its beneficial effects on human health. Three species of <em>Curcuma, Curcuma longa</em> L., <em>Curcuma xanthorrhiza</em>, and <em>Curcuma manga</em>, have been utilized because of their biological and pharmacological activities. Different origins truly affected the metabolite compositions of <em>Curcuma</em> species, thus affecting the biological effects. This research aimed to apply a non-targeted metabolomics approach utilizing liquid chromatography-high resolution mass spectrometry (LC-HRMS) incorporated with chemometrics of principal component analysis (PCA) and partial least square-discriminant analysis (PLS-DA) for identification of global metabolomics profiles and discrimination of <em>C. longa</em> L., <em>C. xanthorrhiza</em>, and <em>C. manga</em> from different origins. Species and origin-based variations in metabolite composition were clearly visualized through PCA and PLS-DA score plots. Key discriminating metabolites, such as curcumin and (+)-nootkatone, were identified using variable importance in projection (VIP) values, confirming their role in distinguishing among species and origins. These findings suggest that environmental factors significantly influence the metabolic profiles of <em>Curcuma</em> species. In conclusion, this study highlights the potential of LC-HRMS-based non-targeted metabolomics combined with chemometric analysis as a reliable tool for the authentication, classification, and quality control of <em>Curcuma</em> species, supporting their safe and standardized use in pharmaceutical and nutraceutical applications.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105140"},"PeriodicalIF":2.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145107094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-19DOI: 10.1016/j.bse.2025.105141
Xuelin Chen , Hanlei Wang , Kun Zhang , Jing Lu , Yumei Zhang
For the phytochemical studies of the fruits of Kochia scoparia (L.) Schrad. (Kochiae Fructus, KF), we isolated chemical components from KF. Twenty compounds, including six alkaloids (1–6), nine polyphenols (7–15), three flavonoids (16–18), and two sterols (19–20) were isolated and identified from the ethanol extract of KF by chromatographic and spectroscopic techniques. Compounds 2, 3, and 5–16 were isolated from KF and Kochia genus for the first time. Furthermore, by discussing the taxonomic significance of these secondary metabolites, we found that Araliaceae, Compositae, Ranunculaceae, and Leguminosae might have a close evolutionary relationship. In conclusion, these results provide new insights into the chemical diversity and chemotaxonomic significance of K. scoparia in the Kochia genus and the Chenopodiaceae family.
{"title":"Chemical constituents from the fruits of Kochia scoparia and their chemotaxonomic significance","authors":"Xuelin Chen , Hanlei Wang , Kun Zhang , Jing Lu , Yumei Zhang","doi":"10.1016/j.bse.2025.105141","DOIUrl":"10.1016/j.bse.2025.105141","url":null,"abstract":"<div><div>For the phytochemical studies of the fruits of <em>Kochia scoparia</em> (L.) Schrad. (Kochiae Fructus, KF), we isolated chemical components from KF. Twenty compounds, including six alkaloids (<strong>1</strong>–<strong>6</strong>), nine polyphenols (<strong>7</strong>–<strong>15</strong>), three flavonoids (<strong>16</strong>–<strong>18</strong>), and two sterols (<strong>19</strong>–<strong>20</strong>) were isolated and identified from the ethanol extract of KF by chromatographic and spectroscopic techniques. Compounds <strong>2</strong>, <strong>3</strong>, and <strong>5</strong>–<strong>16</strong> were isolated from KF and <em>Kochia</em> genus for the first time. Furthermore, by discussing the taxonomic significance of these secondary metabolites, we found that Araliaceae, Compositae, Ranunculaceae, and Leguminosae might have a close evolutionary relationship. In conclusion, these results provide new insights into the chemical diversity and chemotaxonomic significance of <em>K. scoparia</em> in the <em>Kochia</em> genus and the Chenopodiaceae family.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"124 ","pages":"Article 105141"},"PeriodicalIF":2.0,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145106553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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