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Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-20 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.20
Theo Fromme, Maximilian L Spiekermann, Florian Lehmann, Stephan Barcikowski, Thomas Seidensticker, Sven Reichenberger

Pulsed laser ablation in liquids (LAL) is an established preparation method of nanoparticles and catalysts, which additionally allows to chemically modify the nanomaterials in situ via chemical reactions of the nanoparticles with the molecules or solutes of the liquid. Particularly when organic solvents are used as liquids, photothermally induced C-C cleavage, addition or dehydrogenation reactions of the solvents, as well as (carbon) functionalization of the nanoparticles have been observed, which ultimately should affect their lipophilicity and, hence, colloidal stability in apolar or polar solvents. Two-phase liquid systems and the possibility to transfer the surfactant-free nanoparticles from one liquid phase into another remain practically unaddressed in literature. To tackle this knowledge gap, the present study investigates the phase preference of laser-generated noble metal (Au and Ag) and base metal (Cu, Fe, Al and Ti) nanoparticles within propylene carbonate/alcohol (PC/A) systems. Alcohols of increasing chain length (C6-C11) and hence decreasing polarity were chosen for this study. For each metal, LAL was performed at elevated temperatures (85 °C) where the PC/A mixture forms a single phase. Upon cooling, the phases separated and the amount of colloidal nanoparticles in the alcohol and propylene carbonate phase was analyzed for each metal system. The abundance of nanoparticles in PC or alcohol was found to correlate with the electrochemical reduction potential of the respective metal, where the noble metals were enriched within the more polar solvents. The polarity of the solvents (as function of the carbon chain length of the alcohol) was found to direct both the nanoparticles' phase selectivity and recovery after cycling. The observed correlations provide potential guidelines for nanoparticle extraction and size separation, relevant for phase transfer and cycling during homogeneous catalysis.

{"title":"Preferential enrichment and extraction of laser-synthesized nanoparticles in organic phases.","authors":"Theo Fromme, Maximilian L Spiekermann, Florian Lehmann, Stephan Barcikowski, Thomas Seidensticker, Sven Reichenberger","doi":"10.3762/bjnano.16.20","DOIUrl":"10.3762/bjnano.16.20","url":null,"abstract":"<p><p>Pulsed laser ablation in liquids (LAL) is an established preparation method of nanoparticles and catalysts, which additionally allows to chemically modify the nanomaterials in situ via chemical reactions of the nanoparticles with the molecules or solutes of the liquid. Particularly when organic solvents are used as liquids, photothermally induced C-C cleavage, addition or dehydrogenation reactions of the solvents, as well as (carbon) functionalization of the nanoparticles have been observed, which ultimately should affect their lipophilicity and, hence, colloidal stability in apolar or polar solvents. Two-phase liquid systems and the possibility to transfer the surfactant-free nanoparticles from one liquid phase into another remain practically unaddressed in literature. To tackle this knowledge gap, the present study investigates the phase preference of laser-generated noble metal (Au and Ag) and base metal (Cu, Fe, Al and Ti) nanoparticles within propylene carbonate/alcohol (PC/A) systems. Alcohols of increasing chain length (C<sub>6</sub>-C<sub>11</sub>) and hence decreasing polarity were chosen for this study. For each metal, LAL was performed at elevated temperatures (85 °C) where the PC/A mixture forms a single phase. Upon cooling, the phases separated and the amount of colloidal nanoparticles in the alcohol and propylene carbonate phase was analyzed for each metal system. The abundance of nanoparticles in PC or alcohol was found to correlate with the electrochemical reduction potential of the respective metal, where the noble metals were enriched within the more polar solvents. The polarity of the solvents (as function of the carbon chain length of the alcohol) was found to direct both the nanoparticles' phase selectivity and recovery after cycling. The observed correlations provide potential guidelines for nanoparticle extraction and size separation, relevant for phase transfer and cycling during homogeneous catalysis.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"254-263"},"PeriodicalIF":2.6,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849555/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiosensitizing properties of dual-functionalized carbon nanostructures loaded with temozolomide.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.18
Radmila Milenkovska, Nikola Geskovski, Dushko Shalabalija, Ljubica Mihailova, Petre Makreski, Dushko Lukarski, Igor Stojkovski, Maja Simonoska Crcarevska, Kristina Mladenovska
<p><p>In the present study, temozolomide (TMZ), a drug used for the treatment of anaplastic astrocytoma and glioblastoma multiforme (GBM), was incorporated into multiwalled carbon nanotubes (MWCNTs) and a MWCNTs-graphene (MWCNTs-G) hybrid compound, covalently functionalized with polyethylene glycol (PEG) 6000 and folic acid (FA), with an aim to prepare nanocarriers with the potential to prolong the drug circulation time, cross the blood-brain-tumor barrier (BBTB), and provide targeted and controlled drug release in the brain tumor cells. Cytotoxicity and effects on cell membrane integrity of the blank and TMZ-loaded dual-functionalized carbon nanostructures (CNs) were evaluated in vitro on a GBM cell line (U87MG), as well as their radiosensitizing properties after exposure of the pre-treated GBM cells to gamma radiation with a standard clinical dose for patients with GBM. All prepared formulations underwent biopharmaceutical and physicochemical characterization, including the formulations exposed to irradiation under the same conditions. For physicochemical characterization of the formulations, different techniques were used by which successful functionalization of the CNs and TMZ loading were confirmed and visualized; no significant changes in the structure of the CNs and TMZ after irradiation were observed. With single and dual functionalization, formulations with relatively high TMZ loading efficiency and drug content were prepared. They exhibited homogeneous particle size distributions and mean particle sizes and surface charges suitable for crossing the BBTB and targeting brain cancer cells. A biphasic drug release profile was observed for all functionalized TMZ-loaded formulations in simulated in vivo conditions, with a sustained release pointing to the potential for controlled release of TMZ in brain tumor cells. The formulations of the hybrid CN MWCNTs-G compared to the corresponding MWCNTs were characterized by a similar or slightly higher TMZ content, larger particle size, similar surface charge, and slightly faster TMZ release, which can be attributed to the planar structure of graphene that promotes TMZ binding to the surface on a larger scale. For the irradiated CNs, lower values for particle size, more positive values for surface charge, and accelerated TMZ release were observed, which could be explained by changes in the physicochemical characteristics of the prepared formulations upon irradiation. Significant concentration-dependent toxicity was observed for blank dual-functionalized CNs, being higher for MWCNTs-G-PEG6000-FA compared to MWCNTs-PEG6000-FA at the same formulation concentrations. With incorporation of TMZ into the functionalized CNs, the cell viability additionally decreased, maintaining the trend for higher cytotoxicity of the hybrid CN. Additional decrease in the viability of cells was observed when GBM cells pre-treated with the corresponding CNs were exposed to irradiation, which could be ascribed to changes in s
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引用次数: 0
Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-18 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.17
Bedah Rupaedah, Indrika Novella, Atiek Rostika Noviyanti, Diana Rakhmawaty Eddy, Anna Safarrida, Abdul Hapid, Zhafira Amila Haqqa, Suryana Suryana, Irwan Kurnia, Fathiyah Inayatirrahmi

Preserving the viability of rhizobacteria during plant application poses a significant challenge when utilizing rhizobacteria as biofertilizers, especially under adverse environmental conditions. Therefore, the selection of a suitable carrier material for rhizobacteria plays a crucial role in ensuring the sustained viability of these microorganisms. Nanomaterials, particularly nanohydroxyapatite (nHA), have garnered attention for sustaining rhizobacterial viability, high loading capacity, high biodegradability, and biocompatibility, which facilitate microbial interactions. In this study, nHA was synthesized using a hydrothermal method and used as a carrier for two rhizobacteria strains (Pd and Tb). The structural and morphological properties of nHA were examined through XRD and scanning electron microscopy analyses. Rhizobacteria were encapsulated within the carrier material, and their viability was evaluated using the total plate count method. Following their immobilization on nHA, the phosphate-solubilizing capacity of rhizobacteria was evaluated using Pikovskaya's medium. A nitrogen-free bromothymol medium was utilized to qualitatively assess the nitrogen-fixing ability of rhizobacteria. Furthermore, rhizobacteria were identified using 16S rRNA gene sequencing, followed by analysis to construct a phylogenetic tree. nHA was found to meet the required quality criteria, exhibiting a spherical morphology with an average particle size of 68 nm and a porosity of 54.78%. The nHA carrier demonstrated favorable physical attributes to sustaining rhizobacterial viability with pH 8.95 and an electrical conductivity of 55.4 μS/cm. Rhizobacteria loaded onto the nHA carrier maintained comparable viability to those without carriers. The highest viability of the rhizobacterial strains Pd and Tb loaded onto the nHA carrier was observed on the seventh day after inoculation, measuring at 2.480 × 107 and 1.040 × 107 CFU/mL, respectively. The qualitative tests of nHA as rhizobacterial carrier demonstrated that rhizobacteria retained their ability to solubilize phosphate and fix nitrogen. Furthermore, both rhizobacteria have been identified. Pd rhizobacterium was identified with complete match to Brevundimonas olei strain Prd2. Similarly, Tb rhizobacterium showed 100% similarity to Bacillus altitudinis strain NPB34b. Based on this reseach, nanohydroxyapatite could be the potential carrier to protect rhizobacteria from external stressors and to maintain their viability over the long term. These findings indicate the potential of a nanohydroxyapatite-rhizobacteria system as a promising environmentally friendly fertilizer.

{"title":"Synthesis and the impact of hydroxyapatite nanoparticles on the viability and activity of rhizobacteria.","authors":"Bedah Rupaedah, Indrika Novella, Atiek Rostika Noviyanti, Diana Rakhmawaty Eddy, Anna Safarrida, Abdul Hapid, Zhafira Amila Haqqa, Suryana Suryana, Irwan Kurnia, Fathiyah Inayatirrahmi","doi":"10.3762/bjnano.16.17","DOIUrl":"10.3762/bjnano.16.17","url":null,"abstract":"<p><p>Preserving the viability of rhizobacteria during plant application poses a significant challenge when utilizing rhizobacteria as biofertilizers, especially under adverse environmental conditions. Therefore, the selection of a suitable carrier material for rhizobacteria plays a crucial role in ensuring the sustained viability of these microorganisms. Nanomaterials, particularly nanohydroxyapatite (nHA), have garnered attention for sustaining rhizobacterial viability, high loading capacity, high biodegradability, and biocompatibility, which facilitate microbial interactions. In this study, nHA was synthesized using a hydrothermal method and used as a carrier for two rhizobacteria strains (Pd and Tb). The structural and morphological properties of nHA were examined through XRD and scanning electron microscopy analyses. Rhizobacteria were encapsulated within the carrier material, and their viability was evaluated using the total plate count method. Following their immobilization on nHA, the phosphate-solubilizing capacity of rhizobacteria was evaluated using Pikovskaya's medium. A nitrogen-free bromothymol medium was utilized to qualitatively assess the nitrogen-fixing ability of rhizobacteria. Furthermore, rhizobacteria were identified using 16S rRNA gene sequencing, followed by analysis to construct a phylogenetic tree. nHA was found to meet the required quality criteria, exhibiting a spherical morphology with an average particle size of 68 nm and a porosity of 54.78%. The nHA carrier demonstrated favorable physical attributes to sustaining rhizobacterial viability with pH 8.95 and an electrical conductivity of 55.4 μS/cm. Rhizobacteria loaded onto the nHA carrier maintained comparable viability to those without carriers. The highest viability of the rhizobacterial strains Pd and Tb loaded onto the nHA carrier was observed on the seventh day after inoculation, measuring at 2.480 × 10<sup>7</sup> and 1.040 × 10<sup>7</sup> CFU/mL, respectively. The qualitative tests of nHA as rhizobacterial carrier demonstrated that rhizobacteria retained their ability to solubilize phosphate and fix nitrogen. Furthermore, both rhizobacteria have been identified. Pd rhizobacterium was identified with complete match to <i>Brevundimonas olei</i> strain Prd2. Similarly, Tb rhizobacterium showed 100% similarity to <i>Bacillus altitudinis</i> strain NPB34b. Based on this reseach, nanohydroxyapatite could be the potential carrier to protect rhizobacteria from external stressors and to maintain their viability over the long term. These findings indicate the potential of a nanohydroxyapatite-rhizobacteria system as a promising environmentally friendly fertilizer.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"216-228"},"PeriodicalIF":2.6,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent advances in photothermal nanomaterials for ophthalmic applications.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-17 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.16
Jiayuan Zhuang, Linhui Jia, Chenghao Li, Rui Yang, Jiapeng Wang, Wen-An Wang, Heng Zhou, Xiangxia Luo

The human eye, with its remarkable resolution of up to 576 million pixels, grants us the ability to perceive the world with astonishing accuracy. Despite this, over 2 billion people globally suffer from visual impairments or blindness, primarily because of the limitations of current ophthalmic treatment technologies. This underscores an urgent need for more advanced therapeutic approaches to effectively halt or even reverse the progression of eye diseases. The rapid advancement of nanotechnology offers promising pathways for the development of novel ophthalmic therapies. Notably, photothermal nanomaterials, particularly well-suited for the transparent tissues of the eye, have emerged as a potential game changer. These materials enable precise and controllable photothermal therapy by effectively manipulating the distribution of the thermal field. Moreover, they extend beyond the conventional boundaries of thermal therapy, achieving unparalleled therapeutic effects through their diverse composite structures and demonstrating enormous potential in promoting retinal drug delivery and photoacoustic imaging. This paper provides a comprehensive summary of the structure-activity relationship between the photothermal properties of these nanomaterials and their innovative therapeutic mechanisms. We review the latest research on photothermal nanomaterial-based treatments for various eye diseases. Additionally, we discuss the current challenges and future perspectives in this field, with a focus on enhancing global visual health.

{"title":"Recent advances in photothermal nanomaterials for ophthalmic applications.","authors":"Jiayuan Zhuang, Linhui Jia, Chenghao Li, Rui Yang, Jiapeng Wang, Wen-An Wang, Heng Zhou, Xiangxia Luo","doi":"10.3762/bjnano.16.16","DOIUrl":"10.3762/bjnano.16.16","url":null,"abstract":"<p><p>The human eye, with its remarkable resolution of up to 576 million pixels, grants us the ability to perceive the world with astonishing accuracy. Despite this, over 2 billion people globally suffer from visual impairments or blindness, primarily because of the limitations of current ophthalmic treatment technologies. This underscores an urgent need for more advanced therapeutic approaches to effectively halt or even reverse the progression of eye diseases. The rapid advancement of nanotechnology offers promising pathways for the development of novel ophthalmic therapies. Notably, photothermal nanomaterials, particularly well-suited for the transparent tissues of the eye, have emerged as a potential game changer. These materials enable precise and controllable photothermal therapy by effectively manipulating the distribution of the thermal field. Moreover, they extend beyond the conventional boundaries of thermal therapy, achieving unparalleled therapeutic effects through their diverse composite structures and demonstrating enormous potential in promoting retinal drug delivery and photoacoustic imaging. This paper provides a comprehensive summary of the structure-activity relationship between the photothermal properties of these nanomaterials and their innovative therapeutic mechanisms. We review the latest research on photothermal nanomaterial-based treatments for various eye diseases. Additionally, we discuss the current challenges and future perspectives in this field, with a focus on enhancing global visual health.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"195-215"},"PeriodicalIF":2.6,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11849557/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143490450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Probing the potential of rare earth elements in the development of new anticancer drugs: single molecule studies.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-14 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.15
Josiane A D Batista, Rayane M de Oliveira, Carlos H M Lima, Milton L Lana Júnior, Virgílio C Dos Anjos, Maria J V Bell, Márcio S Rocha

We use optical tweezers and atomic force microscopy to investigate the potential of rare earth elements to be used as anticancer agents in the development of new chemotherapeutic drugs by characterizing the binding of three rare earths (ytterbium, neodymium, and erbium) to double-stranded DNA, which is one of the main targets for these drugs inside cells. The three elements presented a significant interaction with the biopolymer in buffers of physiological relevance, typically binding with very high equilibrium association constants (106 to 107 M-1) at the DNA grooves. Furthermore, neodymium and erbium can also induce a very strong compaction/condensation of the double helix at high concentrations, promoting DNA collapse at the single molecule level in a similar way to what occurs with classical DNA condensing agents such as polycations and depletants.

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引用次数: 0
A review of metal-organic frameworks and polymers in mixed matrix membranes for CO2 capture.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.14
Charlotte Skjold Qvist Christensen, Nicholas Hansen, Mahboubeh Motadayen, Nina Lock, Martin Lahn Henriksen, Jonathan Quinson

Polymeric membranes offer an appealing solution for sustainable CO2 capture, with potential for large-scale deployment. However, balancing high permeability and selectivity is an inherent challenge for pristine membranes. To address this challenge, the development of mixed matrix membranes (MMMs) is a promising strategy. MMMs are obtained by carefully integrating porous nano-fillers into polymeric matrices, enabling the simultaneous enhancement of selectivity and permeability. In particular, metal-organic frameworks (MOFs) have gained recognition as MMM fillers for CO2 capture. Here, a review of the current state, recent advancements, and challenges in the fabrication and engineering of MMMs with MOFs for selective CO2 capture is proposed. Key considerations and promising research directions to fully exploit the gas separation potential of MOF-based MMMs in CO2 capture applications are highlighted.

{"title":"A review of metal-organic frameworks and polymers in mixed matrix membranes for CO<sub>2</sub> capture.","authors":"Charlotte Skjold Qvist Christensen, Nicholas Hansen, Mahboubeh Motadayen, Nina Lock, Martin Lahn Henriksen, Jonathan Quinson","doi":"10.3762/bjnano.16.14","DOIUrl":"10.3762/bjnano.16.14","url":null,"abstract":"<p><p>Polymeric membranes offer an appealing solution for sustainable CO<sub>2</sub> capture, with potential for large-scale deployment. However, balancing high permeability and selectivity is an inherent challenge for pristine membranes. To address this challenge, the development of mixed matrix membranes (MMMs) is a promising strategy. MMMs are obtained by carefully integrating porous nano-fillers into polymeric matrices, enabling the simultaneous enhancement of selectivity and permeability. In particular, metal-organic frameworks (MOFs) have gained recognition as MMM fillers for CO<sub>2</sub> capture. Here, a review of the current state, recent advancements, and challenges in the fabrication and engineering of MMMs with MOFs for selective CO<sub>2</sub> capture is proposed. Key considerations and promising research directions to fully exploit the gas separation potential of MOF-based MMMs in CO<sub>2</sub> capture applications are highlighted.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"155-186"},"PeriodicalIF":2.6,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.13
Silvia Jaerger, Patricia Appelt, Mario Antônio Alves da Cunha, Fabián Ccahuana Ayma, Ricardo Schneider, Carla Bittencourt, Fauze Jacó Anaissi

Bentonite clay sourced from the Guarapuava region, Brazil, was modified with niobium oxide (BEOx) and niobium phosphate (BEPh) to act as an adsorbent and photocatalyst in the remediation of wastewater containing methylene blue (MB) dye. Additionally, colored materials were evaluated for their potential as antibacterial hybrid pigments. The bentonite clay modified with niobium was prepared by a solution containing swelling clay mixed with niobium oxide (NbOx) and niobium phosphate (NbPh) in a water solution; after that, the suspension was calcinated. X-ray diffractometry, X-ray photoelectron spectroscopy, and laser-induced breakdown spectroscopy assessed the modifications induced by the incorporation of niobium compounds into the clay, confirming the presence of niobium in the bentonite clay. Following characterization, the BEOx and BEPh samples were used as adsorbents or photocatalysts for treating solutions containing the MB dye (400 mg·L-1) at 25 °C. The results showed adsorption and photocatalysis efficiency above 94% for both samples. The blue-colored BEOx and BEPh samples were then applied as a hybrid pigment. The power pigment and its dispersion in colorless paint were evaluated by the CIEL*a*b* color space, and the ΔE parameters show values above 12, indicating a very strong color parameter difference. Subsequently, the efficacy of BEOx and BEPh as a hybrid pigment was assessed using the minimum inhibitory concentration (MIC) assay against two bacteria strains: Bacillus cereus (ATCC 10876) and Proteus mirabilis (ATCC 35649). The analysis revealed remarkable antibacterial activity against Proteus mirabilis, suggesting a preferential selectivity for Gram-negative bacteria.

{"title":"Clays enhanced with niobium: potential in wastewater treatment and reuse as pigment with antibacterial activity.","authors":"Silvia Jaerger, Patricia Appelt, Mario Antônio Alves da Cunha, Fabián Ccahuana Ayma, Ricardo Schneider, Carla Bittencourt, Fauze Jacó Anaissi","doi":"10.3762/bjnano.16.13","DOIUrl":"10.3762/bjnano.16.13","url":null,"abstract":"<p><p>Bentonite clay sourced from the Guarapuava region, Brazil, was modified with niobium oxide (BEOx) and niobium phosphate (BEPh) to act as an adsorbent and photocatalyst in the remediation of wastewater containing methylene blue (MB) dye. Additionally, colored materials were evaluated for their potential as antibacterial hybrid pigments. The bentonite clay modified with niobium was prepared by a solution containing swelling clay mixed with niobium oxide (NbOx) and niobium phosphate (NbPh) in a water solution; after that, the suspension was calcinated. X-ray diffractometry, X-ray photoelectron spectroscopy, and laser-induced breakdown spectroscopy assessed the modifications induced by the incorporation of niobium compounds into the clay, confirming the presence of niobium in the bentonite clay. Following characterization, the BEOx and BEPh samples were used as adsorbents or photocatalysts for treating solutions containing the MB dye (400 mg·L<sup>-1</sup>) at 25 °C. The results showed adsorption and photocatalysis efficiency above 94% for both samples. The blue-colored BEOx and BEPh samples were then applied as a hybrid pigment. The power pigment and its dispersion in colorless paint were evaluated by the CIEL*a*b* color space, and the Δ<i>E</i> parameters show values above 12, indicating a very strong color parameter difference. Subsequently, the efficacy of BEOx and BEPh as a hybrid pigment was assessed using the minimum inhibitory concentration (MIC) assay against two bacteria strains: <i>Bacillus cereus</i> (ATCC 10876) and <i>Proteus mirabilis</i> (ATCC 35649). The analysis revealed remarkable antibacterial activity against <i>Proteus mirabilis</i>, suggesting a preferential selectivity for Gram-negative bacteria.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"141-154"},"PeriodicalIF":2.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833176/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TiO2 immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.12
Marina G Shelyapina, Rosario Isidro Yocupicio-Gaxiola, Gleb A Valkovsky, Vitalii Petranovskii

A series of novel TiO2/2D mordenite nanocomposites were synthetized by the introduction of titanium tetraethoxide (TEOT) into the interlamellar space of 2D mordenite, its subsequent hydrolysis in water or a solution of 70% ethanol in water for 6, 12, and 24 h, and calcination. The resulting TiO2/2D mordenite materials were studied by a set of complementary characterization techniques, including XRD, SEM-EDX, TGA, N2 sorption, NMR, XPS and UV-vis spectrometry. It was observed that treatment in 70% ethanol solution preserves the ordered layered structure of 2D mordenite because TEOT hydrolysis is slowed down. This, in turn, leads to higher mesoporosity after calcination due to anatase nanoparticles of about 4 nm preventing the collapse of the interlamellar space. Immobilization of TiO2 on the zeolite surface is evidenced by the formation of Si-O-Ti bonds. The bandgap width of the synthetized nanocomposites was found to be sensitive to the hydrolysis medium.

{"title":"TiO<sub>2</sub> immobilized on 2D mordenite: effect of hydrolysis conditions on structural, textural, and optical characteristics of the nanocomposites.","authors":"Marina G Shelyapina, Rosario Isidro Yocupicio-Gaxiola, Gleb A Valkovsky, Vitalii Petranovskii","doi":"10.3762/bjnano.16.12","DOIUrl":"10.3762/bjnano.16.12","url":null,"abstract":"<p><p>A series of novel TiO<sub>2</sub>/2D mordenite nanocomposites were synthetized by the introduction of titanium tetraethoxide (TEOT) into the interlamellar space of 2D mordenite, its subsequent hydrolysis in water or a solution of 70% ethanol in water for 6, 12, and 24 h, and calcination. The resulting TiO<sub>2</sub>/2D mordenite materials were studied by a set of complementary characterization techniques, including XRD, SEM-EDX, TGA, N<sub>2</sub> sorption, NMR, XPS and UV-vis spectrometry. It was observed that treatment in 70% ethanol solution preserves the ordered layered structure of 2D mordenite because TEOT hydrolysis is slowed down. This, in turn, leads to higher mesoporosity after calcination due to anatase nanoparticles of about 4 nm preventing the collapse of the interlamellar space. Immobilization of TiO<sub>2</sub> on the zeolite surface is evidenced by the formation of Si-O-Ti bonds. The bandgap width of the synthetized nanocomposites was found to be sensitive to the hydrolysis medium.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"128-140"},"PeriodicalIF":2.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11833174/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143447868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-02-06 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.11
Deepika K, Arjun Singh

Perovskite solar cells (PSCs) are in the focus of the photovoltaic industry. Lead-free double perovskite solar cells (DPSCs) have become an essential alternative of lead-based PSCs as a promising photovoltaic material. The double perovskite layer is a remarkable choice as active layer because of intrinsic carrier stability, low exciton binding energy, and low toxicity. Herein, the optimization of a planar DPSC with a multifunctional double perovskite absorber layer, that is, La2NiMnO6 (LNMO), is studied with the organic and inorganic hole transport layers (HTLs) Cu2O and PEDOT:PSS. Our study yields a significant improvement in the power conversion efficiency (PCE) of perovskite solar cells with two types of HTLs. The optimized devices achieved a maximum PCE of 27.84% and 27.38% for Cu2O and PEDOT:PSS, respectively, with corresponding open-circuit voltages of 1.27 and 1.22 V, short-circuit current densities of 28.60 and 28.91 mA/cm2, and fill factors of 76.31% and 77.15%, respectively. These results highlight the potential of these HTLs for enhanced device performance.

{"title":"Comparison of organic and inorganic hole transport layers in double perovskite material-based solar cell.","authors":"Deepika K, Arjun Singh","doi":"10.3762/bjnano.16.11","DOIUrl":"10.3762/bjnano.16.11","url":null,"abstract":"<p><p>Perovskite solar cells (PSCs) are in the focus of the photovoltaic industry. Lead-free double perovskite solar cells (DPSCs) have become an essential alternative of lead-based PSCs as a promising photovoltaic material. The double perovskite layer is a remarkable choice as active layer because of intrinsic carrier stability, low exciton binding energy, and low toxicity. Herein, the optimization of a planar DPSC with a multifunctional double perovskite absorber layer, that is, La<sub>2</sub>NiMnO<sub>6</sub> (LNMO), is studied with the organic and inorganic hole transport layers (HTLs) Cu<sub>2</sub>O and PEDOT:PSS. Our study yields a significant improvement in the power conversion efficiency (PCE) of perovskite solar cells with two types of HTLs. The optimized devices achieved a maximum PCE of 27.84% and 27.38% for Cu<sub>2</sub>O and PEDOT:PSS, respectively, with corresponding open-circuit voltages of 1.27 and 1.22 V, short-circuit current densities of 28.60 and 28.91 mA/cm<sup>2</sup>, and fill factors of 76.31% and 77.15%, respectively. These results highlight the potential of these HTLs for enhanced device performance.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"119-127"},"PeriodicalIF":2.6,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy.
IF 2.6 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Pub Date : 2025-01-31 eCollection Date: 2025-01-01 DOI: 10.3762/bjnano.16.10
Naths Grazia Sukubo, Paolo Bigini, Annalisa Morelli

In the coming decades, the development of nanocarriers (NCs) for targeted drug delivery will mark a significant advance in the field of pharmacology. NCs can improve drug solubility, ensure precise distribution, and enable passage across biological barriers. Despite these potential advantages, the interaction with many biological matrices, particularly with existing macrophages, must be considered. In this review, we will explore the dual role of macrophages in NC delivery, highlighting their physiological functions, the challenges posed by the mononuclear phagocyte system, and innovative strategies to exploit macrophage interactions for therapeutic advantage. Recent advancements in treating liver and lung diseases, particularly focusing on macrophage polarization and RNA-based therapies, have highlighted the potential developments in macrophage-NC interaction. Furthermore, we will delve into the intriguing potential of nanomedicine in neurology and traumatology, associated with macrophage interaction, and the exciting possibilities it holds for the future.

{"title":"Nanocarriers and macrophage interaction: from a potential hurdle to an alternative therapeutic strategy.","authors":"Naths Grazia Sukubo, Paolo Bigini, Annalisa Morelli","doi":"10.3762/bjnano.16.10","DOIUrl":"10.3762/bjnano.16.10","url":null,"abstract":"<p><p>In the coming decades, the development of nanocarriers (NCs) for targeted drug delivery will mark a significant advance in the field of pharmacology. NCs can improve drug solubility, ensure precise distribution, and enable passage across biological barriers. Despite these potential advantages, the interaction with many biological matrices, particularly with existing macrophages, must be considered. In this review, we will explore the dual role of macrophages in NC delivery, highlighting their physiological functions, the challenges posed by the mononuclear phagocyte system, and innovative strategies to exploit macrophage interactions for therapeutic advantage. Recent advancements in treating liver and lung diseases, particularly focusing on macrophage polarization and RNA-based therapies, have highlighted the potential developments in macrophage-NC interaction. Furthermore, we will delve into the intriguing potential of nanomedicine in neurology and traumatology, associated with macrophage interaction, and the exciting possibilities it holds for the future.</p>","PeriodicalId":8802,"journal":{"name":"Beilstein Journal of Nanotechnology","volume":"16 ","pages":"97-118"},"PeriodicalIF":2.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11789677/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143121961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Beilstein Journal of Nanotechnology
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