Pub Date : 2023-09-19DOI: 10.21608/bmfj.2023.230932.1879
Eman Abd Almonaem, Osama elfiqy, Omima Abdel Haie, Aya Wahdan
: Background: Necrotising enterocolitis (NEC) is a serious inflammation of the bowel which mostly affects preterm infants. Two to five percent of all admissions to the Neonatal Intensive Care Unit (NICU) are because of NEC. In 85% cases, NEC affects very low birth weight (VLBW) infants (<1500 g) and is a leading cause of mortality and morbidity in preterm neonates. This study aimed to analyze the association between NEC & red blood cell transfusion in very low birth weight in the Neonatal intensive care of Benha University Hospital &Benha Children Hospital. Methods: This was a retrospective case-control study that was conducted on Very Low Birth Weight Infants in Neonatal Intensive Care Units of Benha University Hospital and Benha Children Hospital from November 2018 to November 2020 to identify all infants diagnosed with second stage of NEC or more according to modified Bell„s criteria who were hospitalized to Benha University Hospital& Benha Children Hospital. The number of transfused patients, the frequency of transfusions per patient and the amount of transfused PRBC (ml) were compared in NEC and control groups. Results: The results showed that the frequency of blood transfusion during NICU admission was significantly higher in the NEC group compared to the control group, with a mean of 3.32 ± 0.84 in cases and 1.40 ± 0.55 in controls (P<0.001). regarding logistic regression analysis revealed that the frequency of blood transfusion during NICU admission was significant predictors for NEC patients (P<0.001). In our study, the volume of blood for each transfusion was significantly lower in NEC group compared to controls, with a mean of 17.69 ± 1.37 ml/kg in cases and 19.29 ± 1.23 ml/kg in controls (P<0.001). The total volume of red blood cells (RBC) transfused was also significantly higher in NEC group compared to controls, with a mean of 58.73 ± 15.43 ml/kg in cases and 26.78 ± 10.35 ml/kg in controls (P<0.001). regarding univariate logistic regression analysis revealed that volume of blood for each transfusion in ml/kg, Total volume of RBC in ml/kg was significant predictors for NEC cases (P<0.001), while in Multivariate logistic regression analysis none of these factors was significant predictors for it. Regarding outcome of studied groups, in NEC groups the survivors were 21 (44.7 %), non survivors were 26 (55.3%) while in control group the Survivors were 70 (72.9%) & non survivors were 21 cases (27.1%). Conclusion: Our study revealed that transfusion of red blood cells was significantly associated with the development of NEC in very low birth weight infants. The frequency of blood transfusion during NICU admission was significantly higher in the NEC group compared to the control group, and the total volume of RBC transfusion was also significantly higher in NEC group compared to controls.
{"title":"Associations between Red Blood Cell Transfusions and Necrotizing Enterocolitis in Very Low Birth Weight Infants","authors":"Eman Abd Almonaem, Osama elfiqy, Omima Abdel Haie, Aya Wahdan","doi":"10.21608/bmfj.2023.230932.1879","DOIUrl":"https://doi.org/10.21608/bmfj.2023.230932.1879","url":null,"abstract":": Background: Necrotising enterocolitis (NEC) is a serious inflammation of the bowel which mostly affects preterm infants. Two to five percent of all admissions to the Neonatal Intensive Care Unit (NICU) are because of NEC. In 85% cases, NEC affects very low birth weight (VLBW) infants (<1500 g) and is a leading cause of mortality and morbidity in preterm neonates. This study aimed to analyze the association between NEC & red blood cell transfusion in very low birth weight in the Neonatal intensive care of Benha University Hospital &Benha Children Hospital. Methods: This was a retrospective case-control study that was conducted on Very Low Birth Weight Infants in Neonatal Intensive Care Units of Benha University Hospital and Benha Children Hospital from November 2018 to November 2020 to identify all infants diagnosed with second stage of NEC or more according to modified Bell„s criteria who were hospitalized to Benha University Hospital& Benha Children Hospital. The number of transfused patients, the frequency of transfusions per patient and the amount of transfused PRBC (ml) were compared in NEC and control groups. Results: The results showed that the frequency of blood transfusion during NICU admission was significantly higher in the NEC group compared to the control group, with a mean of 3.32 ± 0.84 in cases and 1.40 ± 0.55 in controls (P<0.001). regarding logistic regression analysis revealed that the frequency of blood transfusion during NICU admission was significant predictors for NEC patients (P<0.001). In our study, the volume of blood for each transfusion was significantly lower in NEC group compared to controls, with a mean of 17.69 ± 1.37 ml/kg in cases and 19.29 ± 1.23 ml/kg in controls (P<0.001). The total volume of red blood cells (RBC) transfused was also significantly higher in NEC group compared to controls, with a mean of 58.73 ± 15.43 ml/kg in cases and 26.78 ± 10.35 ml/kg in controls (P<0.001). regarding univariate logistic regression analysis revealed that volume of blood for each transfusion in ml/kg, Total volume of RBC in ml/kg was significant predictors for NEC cases (P<0.001), while in Multivariate logistic regression analysis none of these factors was significant predictors for it. Regarding outcome of studied groups, in NEC groups the survivors were 21 (44.7 %), non survivors were 26 (55.3%) while in control group the Survivors were 70 (72.9%) & non survivors were 21 cases (27.1%). Conclusion: Our study revealed that transfusion of red blood cells was significantly associated with the development of NEC in very low birth weight infants. The frequency of blood transfusion during NICU admission was significantly higher in the NEC group compared to the control group, and the total volume of RBC transfusion was also significantly higher in NEC group compared to controls.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135109087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-19DOI: 10.21608/bmfj.2023.226167.1868
Walaa Ibrahim El-Desoky, Yousry Rezk, Basem Aglan, Mohamed Sadek
: Background: Capnography has made steady inroads in the ICU and is increasingly used for all patients who are mechanically ventilated. There is growing recognition that capnography is rich in information about lung and circulatory physiology and provides insight into many diseases and treatments. Aim and objectives: to evaluate the Role OF Capnography in Weaning in
{"title":"Role OF Capnography In Weaning in Mechanically Ventillated C0PD Patients","authors":"Walaa Ibrahim El-Desoky, Yousry Rezk, Basem Aglan, Mohamed Sadek","doi":"10.21608/bmfj.2023.226167.1868","DOIUrl":"https://doi.org/10.21608/bmfj.2023.226167.1868","url":null,"abstract":": Background: Capnography has made steady inroads in the ICU and is increasingly used for all patients who are mechanically ventilated. There is growing recognition that capnography is rich in information about lung and circulatory physiology and provides insight into many diseases and treatments. Aim and objectives: to evaluate the Role OF Capnography in Weaning in","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135109090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-19DOI: 10.21608/bmfj.2023.210333.1814
Ashraf foda, Ahmed Shata, Zeinab El-Said
: Background: Postdate pregnancies are difficult pregnancies to carry to term because of increased chance of complications. Misoprostol is an efficient induction strategy. There is a lot of interest in the effects of corticosteroids on cervical ripening and shortening physiological phase of labor. Aim: To assess how intramuscular dexamethasone affected length of labor brought on by vaginal misoprostol in cases of postdate pregnancy. Patients and methods: 100 women with postdate pregnancies were randomized in two groups: Group1 (n= 50) received single dose of 8 mg dexamethazone in 2 mL solution intramuscular and group 2 (n=50) received 2 ml isotonic saline (placebo group). Dexamethasone and placebo groups saw withdrawal of 10 and 11 individuals. Misoprostol (50 µg) at 6-hour intervals was given after prop¬er monitoring. Results: In dexamethazone group, 77.5 % of women gave birth within 12 hours, as opposed to 35.9 % in the placebo group (p < 0.05). When compared to placebo group, dexamethasone group's induction to delivery time was quicker (680.1 ± 55.4 min versus 766.1 ± 58.3 min., p < 0.001). Additionally, time from start of labor induction and start of active phase of labor was shorter in the dexamethazone group as compared to placebo group (253.9 ± 47.4 min versus 306.1 ± 37.2 min., p < 0.001). Additionally, patients in dexamethazone group experienced active phase of labor that was shorter (394.6 ± 36.9 compared 419.1 ± 31.3 min., p = 0.000) and second stage of labor that was much shorter (19.1 ± 2.8 versus 28.7 ± 3.0 min). Conclusions: In postdate pregnancy, intramuscular dexamethasone and vaginal misoprostol reduced interval between labor induction and beginning of active phase of labor. Interval between active stage and second stage of labor also was shorter.
{"title":"Glucocorticoids shorten and speed up the misoprostol-induced labour in postdate pregnancy.","authors":"Ashraf foda, Ahmed Shata, Zeinab El-Said","doi":"10.21608/bmfj.2023.210333.1814","DOIUrl":"https://doi.org/10.21608/bmfj.2023.210333.1814","url":null,"abstract":": Background: Postdate pregnancies are difficult pregnancies to carry to term because of increased chance of complications. Misoprostol is an efficient induction strategy. There is a lot of interest in the effects of corticosteroids on cervical ripening and shortening physiological phase of labor. Aim: To assess how intramuscular dexamethasone affected length of labor brought on by vaginal misoprostol in cases of postdate pregnancy. Patients and methods: 100 women with postdate pregnancies were randomized in two groups: Group1 (n= 50) received single dose of 8 mg dexamethazone in 2 mL solution intramuscular and group 2 (n=50) received 2 ml isotonic saline (placebo group). Dexamethasone and placebo groups saw withdrawal of 10 and 11 individuals. Misoprostol (50 µg) at 6-hour intervals was given after prop¬er monitoring. Results: In dexamethazone group, 77.5 % of women gave birth within 12 hours, as opposed to 35.9 % in the placebo group (p < 0.05). When compared to placebo group, dexamethasone group's induction to delivery time was quicker (680.1 ± 55.4 min versus 766.1 ± 58.3 min., p < 0.001). Additionally, time from start of labor induction and start of active phase of labor was shorter in the dexamethazone group as compared to placebo group (253.9 ± 47.4 min versus 306.1 ± 37.2 min., p < 0.001). Additionally, patients in dexamethazone group experienced active phase of labor that was shorter (394.6 ± 36.9 compared 419.1 ± 31.3 min., p = 0.000) and second stage of labor that was much shorter (19.1 ± 2.8 versus 28.7 ± 3.0 min). Conclusions: In postdate pregnancy, intramuscular dexamethasone and vaginal misoprostol reduced interval between labor induction and beginning of active phase of labor. Interval between active stage and second stage of labor also was shorter.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135109086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-17DOI: 10.21608/bmfj.2023.212530.1822
Omneya Bassyoni, Ebtehal Abdel Aal, Ahmed khalil
: Background : Ovarian cancer is a lethal gynecological malignancy worldwide. The immune system plays a key role in preventing tumor development. Angiogenesis and immune evasion are vital for ovarian cancer progression and metastasis. Aim : This work aimed to evaluate the expression of PD-L1, VEGF and CD8 +T cells in ovarian serous carcinomas and correlate them with clinic-pathological variables. Material and methods : An Immunohistochemical study of PD-L1, VEGF and CD8+ T cells was performed on 50 cases of ovarian serous carcinomas. Results : PD-L1 & VEGF were over-expressed with statistical significance , in higher grade ( P <.01), advanced stage , case with lymph node metastasis and distant metastasis( P <.05) .Higher CD8+ T cells in epithelium and stroma was related to advanced stage, only intraepithelial CD8+ T cells was directly correlated with tumor grade & lymph node metastasis & stage ( P <.05). Positive correlation between PD-L1 & VEGF and Intraepithelial CD8+T cells was detected ( r =.048) Conclusion : Neoplastic cells in ovarian serous carcinomas-expressing PD-L1 and VEGF along with intraepithelial CD8+T cells-might expect poor prognosis. An association between PD-L1 and VEGF could predict their role in immune evasion.
{"title":"Significance of expression of PD-L1, VEGF and CD8+ T cells in ovarian serous carcinoma: an Immunohistochemical study","authors":"Omneya Bassyoni, Ebtehal Abdel Aal, Ahmed khalil","doi":"10.21608/bmfj.2023.212530.1822","DOIUrl":"https://doi.org/10.21608/bmfj.2023.212530.1822","url":null,"abstract":": Background : Ovarian cancer is a lethal gynecological malignancy worldwide. The immune system plays a key role in preventing tumor development. Angiogenesis and immune evasion are vital for ovarian cancer progression and metastasis. Aim : This work aimed to evaluate the expression of PD-L1, VEGF and CD8 +T cells in ovarian serous carcinomas and correlate them with clinic-pathological variables. Material and methods : An Immunohistochemical study of PD-L1, VEGF and CD8+ T cells was performed on 50 cases of ovarian serous carcinomas. Results : PD-L1 & VEGF were over-expressed with statistical significance , in higher grade ( P <.01), advanced stage , case with lymph node metastasis and distant metastasis( P <.05) .Higher CD8+ T cells in epithelium and stroma was related to advanced stage, only intraepithelial CD8+ T cells was directly correlated with tumor grade & lymph node metastasis & stage ( P <.05). Positive correlation between PD-L1 & VEGF and Intraepithelial CD8+T cells was detected ( r =.048) Conclusion : Neoplastic cells in ovarian serous carcinomas-expressing PD-L1 and VEGF along with intraepithelial CD8+T cells-might expect poor prognosis. An association between PD-L1 and VEGF could predict their role in immune evasion.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135259651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
: Background: The COVID-19 infection has firmly established itself as a pandemic that can affect many body systems, including the cardiovascular system.2D speckle tracking echocardiography (2D-STE) can diagnose early subclinical myocardial dysfunction, as many studies have reported an inverse correlation of increased cardiac biomarkers level with global longitudinal strain (GLS) values among COVID-19 patients. Aim: This study assessed the global Left ventricular strain using speckle tracking echocardiography in patients recently recovered from COVID-19 infection. Patients and methods: This study was done in Benha University Hospital from June 2022 to January 2023 and included 100 patients who had positive COVID-19 diagnosis proved by positive polymerase chain reaction (PCR) test of the nasopharyngeal swab within 30 ±5 days. Results: Patients were classified according to the upper laboratory limit of the hs-troponin (11.6) into two groups; with myocardial injury (hs-troponin > 11.6) and without myocardial injury (hs-troponin ≤ 11.6). Patients with myocardial injury had significantly lower EF and LVGLS (P < 0.001). No significant differences were observed regarding ECG abnormality, D-dimer, and TLC. Moreover, LVGLS showed significant negative correlations with age (P < 0.001), hs-troponin (P = 0.013), and D-dimer (P = 0.013). In contrast, it showed a significant positive correlation with EF (P < 0.001), and no significant correlation was observed with TLC (P = 0.408). Conclusion: Serial measurements of cardiac troponin and LVGLS following recovery from COVID‐19 infection has an incremental prognostic value and can be used to evaluate the progression of sub‐clinical LV dysfunction.
{"title":"Speckle tracking echocardiographic assessment of Left ventricular global longitudinal strain in patients recovered from COVID-19","authors":"Abdelrahman Abdelrahman, Heba MANSOUR, Mohamed Hamouda, Safaa Imam","doi":"10.21608/bmfj.2023.223376.1853","DOIUrl":"https://doi.org/10.21608/bmfj.2023.223376.1853","url":null,"abstract":": Background: The COVID-19 infection has firmly established itself as a pandemic that can affect many body systems, including the cardiovascular system.2D speckle tracking echocardiography (2D-STE) can diagnose early subclinical myocardial dysfunction, as many studies have reported an inverse correlation of increased cardiac biomarkers level with global longitudinal strain (GLS) values among COVID-19 patients. Aim: This study assessed the global Left ventricular strain using speckle tracking echocardiography in patients recently recovered from COVID-19 infection. Patients and methods: This study was done in Benha University Hospital from June 2022 to January 2023 and included 100 patients who had positive COVID-19 diagnosis proved by positive polymerase chain reaction (PCR) test of the nasopharyngeal swab within 30 ±5 days. Results: Patients were classified according to the upper laboratory limit of the hs-troponin (11.6) into two groups; with myocardial injury (hs-troponin > 11.6) and without myocardial injury (hs-troponin ≤ 11.6). Patients with myocardial injury had significantly lower EF and LVGLS (P < 0.001). No significant differences were observed regarding ECG abnormality, D-dimer, and TLC. Moreover, LVGLS showed significant negative correlations with age (P < 0.001), hs-troponin (P = 0.013), and D-dimer (P = 0.013). In contrast, it showed a significant positive correlation with EF (P < 0.001), and no significant correlation was observed with TLC (P = 0.408). Conclusion: Serial measurements of cardiac troponin and LVGLS following recovery from COVID‐19 infection has an incremental prognostic value and can be used to evaluate the progression of sub‐clinical LV dysfunction.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135452829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-03DOI: 10.21608/bmfj.2023.212490.1821
Ahmed Elsheikh, Abdel-salam Ahmad, Mohamed Elgendi, Nikolaos Giotakis, Gamal Hosny
{"title":"Analysis of specimens collected from highest and lowest uptake areas according to F18- FDG PET-CT in chronic osteomyelitis","authors":"Ahmed Elsheikh, Abdel-salam Ahmad, Mohamed Elgendi, Nikolaos Giotakis, Gamal Hosny","doi":"10.21608/bmfj.2023.212490.1821","DOIUrl":"https://doi.org/10.21608/bmfj.2023.212490.1821","url":null,"abstract":"","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134948405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-03DOI: 10.21608/bmfj.2023.221152.1848
Mahmoud Rizk, Mohamed El Assal, Fawzy Khalil, El Mokhtar El Hamed Ould Ahmed, Mohamed Afifi
{"title":"Relationship Between Platelet Indices and Severity of COVID-19 Infection.","authors":"Mahmoud Rizk, Mohamed El Assal, Fawzy Khalil, El Mokhtar El Hamed Ould Ahmed, Mohamed Afifi","doi":"10.21608/bmfj.2023.221152.1848","DOIUrl":"https://doi.org/10.21608/bmfj.2023.221152.1848","url":null,"abstract":"","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134948411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/bmfj.2023.213665.1830
Noura Abd Elhameed Ibrahim, Shahen Dabour, Rana Khashaba, Aliaa Elhady
{"title":"Estimation of Osteoprotgrin Level in B Thalassemia Children","authors":"Noura Abd Elhameed Ibrahim, Shahen Dabour, Rana Khashaba, Aliaa Elhady","doi":"10.21608/bmfj.2023.213665.1830","DOIUrl":"https://doi.org/10.21608/bmfj.2023.213665.1830","url":null,"abstract":"","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-01DOI: 10.21608/bmfj.2023.219205.1844
Mahmoud Mohamed Abdullah, Tamer Kamal, Ahmed Shalan, Soha Shaaban Abdel Naby
: Background: To study the value of morphological and functional MRI criteria in diagnosis of carpal tunnel syndrome (CTS) and determine cut-off values between normal individuals and CTS patients. Patients and methods : Forty wrists were examined in 24 patients with CTS diagnosis confirmed by nerve conduction studies (NCS) and in 10 healthy subjects. Cross-sectional area (CSA), fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured at three levels as well as signal intensity ratio (SIR), flattening ratio (FR) and retinacular bowing ratio. Comparison between the two groups was done. Results: CSA is increased in CTS patients compared to healthy controls. The cut off value for CSA at pisiform bone was little more sensitive than maximum CSA. SIR & FR showed no significant difference between CTS patients and control groups. RBR is increased in CTS patients. FA is decreased in CTS patients. A significant positive correlation was found between maximum CSA & highest ADC, and the findings of NCS. A significant negative correlation was found between lowest FA and the findings of NCS. Conclusions: CSA, RBR, FA & ADC are highly significant predictors of carpal tunnel syndrome. FR and SIR are not reliable for diagnosis of carpal tunnel syndrome. Maximum CSA, lowest FA & highest ADC can be used for grading of CTS severity.
{"title":"Added Value of Morphological and Functional Magnetic Resonance Neurography in Assessment of Carpal Tunnel Syndrome in Correlation with Nerve Conduction Studies","authors":"Mahmoud Mohamed Abdullah, Tamer Kamal, Ahmed Shalan, Soha Shaaban Abdel Naby","doi":"10.21608/bmfj.2023.219205.1844","DOIUrl":"https://doi.org/10.21608/bmfj.2023.219205.1844","url":null,"abstract":": Background: To study the value of morphological and functional MRI criteria in diagnosis of carpal tunnel syndrome (CTS) and determine cut-off values between normal individuals and CTS patients. Patients and methods : Forty wrists were examined in 24 patients with CTS diagnosis confirmed by nerve conduction studies (NCS) and in 10 healthy subjects. Cross-sectional area (CSA), fractional anisotropy (FA) and apparent diffusion coefficient (ADC) were measured at three levels as well as signal intensity ratio (SIR), flattening ratio (FR) and retinacular bowing ratio. Comparison between the two groups was done. Results: CSA is increased in CTS patients compared to healthy controls. The cut off value for CSA at pisiform bone was little more sensitive than maximum CSA. SIR & FR showed no significant difference between CTS patients and control groups. RBR is increased in CTS patients. FA is decreased in CTS patients. A significant positive correlation was found between maximum CSA & highest ADC, and the findings of NCS. A significant negative correlation was found between lowest FA and the findings of NCS. Conclusions: CSA, RBR, FA & ADC are highly significant predictors of carpal tunnel syndrome. FR and SIR are not reliable for diagnosis of carpal tunnel syndrome. Maximum CSA, lowest FA & highest ADC can be used for grading of CTS severity.","PeriodicalId":8803,"journal":{"name":"Benha Veterinary Medical Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135248562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：