Irritable bowel syndrome (IBS) is a functional gastrointestinal (GI) disorder thought to affect 10% to 20% of the population worldwide. Essentially the paper is in two parts. The first part of the paper investigates the world literature and a variety of up to date treatment approaches which, with the exception of cognitive-behavioural therapy (CBT) which also has beneficial effects on patients' overall mood and bloating, are designed to manage individual symptoms of IBS. The review examines the efficacy of pharmaceutical agents (antispasmodics, antidepressants, antidiarrhoeals and the new serotonergic modifying agonists/antagonists), dietary control (fibre, lactose free products, partially hydrolyzed guar gum, peppermint oil, prebiotics and probiotics), CBT (with or without the use of an audiotape) and the standard gut-directed hypnotherapy approach of the Manchester Model.
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