Biology, Medicine, & Natural Product Chemistry最新文献

{"title":"Endophytic Fungi Isolated from Pteridium acquilinium and Newbouldia laevis Leaves Exhibited Antioxidant Activities and Inhibitory Potential Against Selected Clinical Bacteria Isolates","authors":"Obinna Ajah, Chika Cecilia Unegbu, Emmanuel N Uzohuo, Ogechi Ozioma Anyanwu, Ugochukwu Moses Okezie, Chioma Anyanwu, Rich Joseph","doi":"10.14421/biomedich.2023.122.547-553","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.547-553","url":null,"abstract":"Endophytic fungi are important components of plant micro-ecosystems and they exist usually inside the healthy tissues of living plants. Endophytes possess encouraging source of biologically active metabolites for pharmaceutical applications. This study isolated endophytic fungi from Pteridium acquilinium and Newbouldia laevis leaves and evaluated their antioxidant and antibacterial activities. A total of ten endophytic fungal species were isolated from the leaves of the plants, from which six were selected and identified, including; Epicoccum thailandicum; Trichoderma atroviride; Lasiodiplodia parva; Trichoderma yunnanense; Colletotrichum cobbittiense; and, Trichoderma crissum. Among the isolated fungi, Trichoderma crissum (266.2956 ± 84.84 µg/ml) and Lasiodiplodia parva (293.0755 ± 64.95 µg/ml) showed significant scavenging activity on comparison with ascorbic acid. Furthermore, the isolated endophytes showed potential antibacterial activity against the tested clinical pathogens. This study validates that endophytic fungi dwelling in the inner tissue of medicinal plants studied could be a potential source of biologically active metabolites with free radical scavenging activities and also for treatment of infectious diseases caused by Staphylococcus aureus, Pseudomonas aeroginosa and Escherichia coli.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136378100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Silico BCell Epitope Design of Zika Virus Vaccine Using “Zika Virus Isolate Zika Virus/H sapiensTc/Tha/2006/CVD_06020 Complete Genome”","authors":"Lisa Savitri, Syntia Tanu Juwita, Ester Lianawati Antoro, Ida Septika Wulansari, Datin An Nisa Sukmawati, João Gregório Freitas, Andre Mario Sequeira Alves Ornai","doi":"10.14421/biomedich.2023.122.525-531","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.525-531","url":null,"abstract":"ZIKV has been found in the cerebrospinal fluid (CSF) and brains of adults infected with viruses that manifest neurological disorders. ZIKV is a mosquito-borne single-stranded RNA virus, which belongs to the family Flaviviridae. The efforts of the scientific community have rapidly increased knowledge about this virus. However, understanding the complexities of ZIKV infection, transmission and pathogenesis remains an urgent challenge. Therefore, it is critical to study competent vectors and natural reservoirs for ZIKV, viral genetic diversity and flavivirus coinfection. Due to the great challenges to develop a ZIKV vaccine, it is still not possible to be immunized against ZIKV infection and related pathologies. The methods are nucleotide search for the Zika virus was carried out in silico, using the NCBI bioinformatics application by providing access to biomedical and genomic information. /H. sapiens-tc/THA/2006/CVD_06-020, the complete genome was then searched for FASTA, then prediction of vaccine epitope using the IEDB. The vaccine candidate peptides were analyzed for their antigenicity using VaxiJen. Proteins were classified by AllerTop to known allergenicity, then ToxinPred to predict and design toxic/non-toxic peptides. There are 30 peptide sequences are predicted to be a candidate of peptides B-cell epitope zika virus vaccine design using “zika virus isolate zika virus/H. sapiens-tc/THA/2006/CVD_06-020, complete genome”.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Targeting H3N2 Influenza Virus RNA-dependent RNA Polymerase by Using Bioactives from Essential Oils from Eucalyptus polybrachtea, Cymbopogon citratus and Cymbopogon khasianus","authors":"Arun Dev Sharma, Inderjeet Kaur","doi":"10.14421/biomedich.2023.122.515-524","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.515-524","url":null,"abstract":"A dramatic surge of H3N2 influenza virus is of grave concern worldwide and particularly in India. H3N2 cause acute respiratory infection, however, a few drugs are available for its mitigation. Subsequently, researchers have been involved in efforts to discover novel antiviral mechanisms that can lay the basis for new anti-influenza drugs. Influenza virus RNA-dependent RNA polymerase (RdRP) is a multi-functional hetero-trimer, implicated in the production of viral mRNA, hence plays a major role in viral infectivity thus directly associated with survival of the virus. RdRP have been cited as anappropriate target for therapeutic drug design. In the present study molecular docking was designed to estimate the effect of potent bioactive moleculesfrom essential oils from Eucalyptus polybrachtea (eucalyptus oil, EO), Cymbopogon citratus (lemon grass essential oil, LEO) and Cymbopogon khasianus (palmarosa essential oil, PEO) against RdRP protein. GC-FID (gas chromatography with flame-ionization detection) based composition profile, and in-silico docking study was conducted by using CB-dock 2 analysis followed by 2D interactions. GC-FID revealed eucalyptol, geranial and geraniolas major phytocompounds in EO, LEO and PEO respectively. The docking score indicated effective binding of ligands to RdRP. Interactions results indicated that, RdRP/ligand complexes form hydrogen, van der waals forces, pi-alkyl, alkyl, and pi-Sigma interactions. Based on above findings of aroma profile and docking, therefore, it was recommended that essential oils from above mentioned aromatic cropsmay represent potential herbal treatment to mitigate H3N2 infections.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135486094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver Protection Effect of Red Rose Petal Methanol Extract in Copper-Induced Liver Injury in Male Wistar Rats","authors":"Caroline Febrina Hutagalung, Ermi Girsang, Maya Sari Mutia, Suhartina Suhartina, Oliviti Natali","doi":"10.14421/biomedich.2023.122.507-513","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.507-513","url":null,"abstract":"The human body requires low amounts of copper to maintain homeostasis, but high copper intake can cause various health problems. Many previous studies have been performed to look for natural products that can neutralize the excessive copper effect; one such natural product is a rose petal. Therefore, this study aims to investigate the liver protection effect of rose petals in copper-induced liver injury in male Wistar rats. This experimental study used thirty male Wistar rats that were grouped into five groups, including control, standard (quercetin), Rose Petal Methanol Extract-1 (400 mg/kg BW), 2 (800 mg/kg BW), and 3 (1,200 mg/kg BW). All groups were treated for 14 days, and all rats were given copper (II) sulfate suspension for the last three days. On the fifteenth day, all rats were sacrificed to obtain blood and liver tissue SGOT, SGPT, and liver histology study. The results showed that rose petal methanol extract significantly decreased SGOT and SGPT levels compared to the control group (P-value <0.05). The reduced area of ballooning degeneration and necrosis were in line with the increased dose of rose petal extract supported the liver protection effect of rose petal extract. Therefore, it can be concluded that rose petal methanol extract protects the liver against copper impacts.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135786529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemicals and Larvicidal Activity of Sonneratia alba Root Extracts from Ngurah Rai Mangrove Forest, Denpasar-Bali","authors":"Made Dharmesti Wijaya, Anak Agung Gede Indraningrat, I Gede Yoga Ayuning Kirtanayasa","doi":"10.14421/biomedich.2023.122.499-505","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.499-505","url":null,"abstract":"Dengue is an endemic disease with a high incidence in almost all Southeast Asian countries, including Indonesia. This infectious disease is caused by a virus transmitted by the bite of Aedes aegypti mosquito as the main vector. Effective mosquito vector control is a crucial step in stopping the spread of this virus. Of the several methods available, the use of larvicides is considered one of the most successful treatments in reducing the number of mosquito vectors. However, widely used synthetic larvicides can have undesirable side effects on the environment and non-target organisms including human health. The aim of this study was to discover a new biolarvicide from natural materials that is relatively safer. In this study, the biolarvicidal activity of mangrove plant species that are commonly found in Ngurah Rai Mangrove Forest Bali was tested, namely Sonneratia alba. Mangrove root simplicia was extracted by reflux method using three different solvents namely methanol, chloroform, and n-hexane. The content of compounds in the extract were analyzed using GC/MS method. The larvicidal activity of the extracts were tested on A. aegypti instar III/IV larvae with concentrations of 0.1, 1, 10, 100, and 1000 ppm for 24 hours. Subsequently, the average value of larval mortality was used to calculate the LC50 of each extract. The results showed that S. alba methanol extract provided the best larvicidal activity compared to chloroform and n-hexane extracts, with mortality of 69.33% at a concentration of 1000 ppm and LC50 of 1265 ppm. GC-MS analysis showed that the methanol extract of S. alba contained five dominant compounds namely Methyl 2-hydroxy-eicosanoate (19.55%); 4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-7-methoxy (16.48%); 4-((1E)-3-Hydroxy-1-propenyl)-2-methoxyphenol (10.06%); Benzamide, N-[4-(2-naphtyl)-2-thiazolyl]- (9.40%); and 2,3-Dihydro-3,5-bis(3-methoxyphenyl)-1H-inden-1-one (6.52%). The results of this study provide a preliminary result on larvicide activity from mangrove S. alba in order to develop bio larvicides from nature which is safer for human health and environment.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136193478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Oil Quality and Antifungal Effect of Selected Citronella Accessions (Cymbopogon nardus, Cymbopogon winterianus) to Formulate an Anti-Dandruff Shampoo","authors":"Rathnayaka Mudiyanselage Nipuni Wijerathna, Achini Anuradha Wijeweera, Anushi Madushani Wijethunga, Mapa Mudiyanselage Sumudu Tharangani Mapa","doi":"10.14421/biomedich.2023.122.485-498","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.485-498","url":null,"abstract":"Citronella is an aromatic grass of the family Poaceae which can be classified into two categories Ceylon Citronella (Cymbopogon nardus) and Java Citronella (Cymbopogon winterianus). The Citronella oil was extracted from five selected Ceylon Citronella (HP T1, HP T2 and HP T3) and Java Citronella (MP T1 and MP T2) accessions using steam distillation and hydrodistillation methods. Citronella oil quantity extracted by hydrodistillation with Xylene from Ceylon Citronella was higher (2.45-2.67 mL/100 g) than the Java Citronella (1.57-1.64 mL/100 g). The oil quantity of Ceylon Citronella (HP T1-5.52 %, HP T2- 1.40 %, HP T3- 1.05 %) and the quantity of Java Citronella (MP T1- 1.25%, MP T2- 1.79%) extracted by hydrodistillation showed a significant difference (P<0.0001) and there was no significant difference (P=0.7055) between the oil quantity of Ceylon (HP T1- 1.07%, HP T2- 1.18 %, HP T3- 1.19%) and Java (MP T1- 1.16%, MP T2- 1.23%) oils extracted by the steam distillation. Both Java and Ceylon Citronella oils showed organoleptic properties with pale yellow to pale brownish yellow colour and a strong citrusy aroma which meets the ISO 3848 and ISO 3849 standards. The oil of Ceylon Citronella accessions showed refractive index (1.465-1.487), relative density (0.893-0.910), and ethanol solubility (1:2 mL) within the ranges specified in SLS 170 standards. Java Citronella oil exhibited the refractive index (1.4660-1.4730), relative density (0.880-0.892), ethanol solubility (1:2 mL), and optical rotation (-5? to 0?) which meets the specifications of ISO 3848 standards. Geraniol, Citronellol, and Citronellal were identified as the major constituents using the gas chromatography-mass spectrometry (GC-MS) where Java Citronella oil showed high Geraniol content (48.60-49.17%) than Ceylon Citronella oil (16.93-26.49%). All types of tested Citronella oil showed inhibition against Candida albicans where HP T3 (1.9 cm) and MP T1(2.0 cm) oils showed the highest promising antifungal activity among Ceylon oils and Java oils respectively. Therefore, these two oils were selected for the antidandruff shampoo formulation. The two antidandruff shampoo samples were formulated with 2% v/v concentrations of HP T3 and MP T1 Citronella oil which were determined as MIC for the inhibition of C. albicans. Antidandruff shampoo tested against C. albicans showed greater antifungal activity (HP T3 - 2.50.05 cm; MP T1 - 2.50.05 cm) than the crude Citronella oil (HP T3- 1.90.11 cm; MP T1-2.00.1 cm), also attained the organoleptic and physical properties such as pH (4.0-8.0), foam height (>100 mL), dirt dispersion (no ink in foam), viscosity, low wetting time and solid content (HP T3-14.750.12%; MP T2-12.330.19%) in acceptable specification range. This study exhibits that Ceylon Citronella oil HP T1 has the highest oil quantity from all selected accessions. Hydrodistillation can be used to extract high oil quantity than the steam distillation method from both Java and Ceylon Citronella typ","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135619319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nephroprotective Activities of Ethanol Root Extract and Fractions of Hippocratea africana Against Doxorubicin-Induced Kidney Toxicity","authors":"Kufre U. Noah, John A. Udobang, Jude E. Okokon, Martin O. Anagboso, Nwakaego Omonigho Ebong","doi":"10.14421/biomedich.2023.122.477-484","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.477-484","url":null,"abstract":"Hippocratea africana root used locally in the treatment of poisoning was investigated to confirm its antidotal potential in rats. The root extract (200-600 mg/kg) and fractions; dichloromethane (DCM) and aqueous, 400 mg/kg) were evaluated for nephroprotective activity against doxorubicin-induced kidney injury in rats. Kidney function parameters, kidney oxidative stress markers and kidney histology were used to assess the kidney protective effect of the extract. The root extract and fractions (200-600 mg/kg) significantly (p<0.05-0.01) reduced the levels of creatinine, urea and electrolytes that were elevated by doxorubicin. Also, the MDA level elevated by doxorubicin was reduced by the extract and fractions co-administration, while the levels of GSH, GST, SOD, GPx, and CAT that were decreased by doxorubicin were significantly (p<0.01) elevated by the root extract/fractions. Histology of the kidney sections of extract/fractions -treated animals showed reductions in the pathological features compared to the organotoxic-treated animals. The chemical pathological changes were consistent with histopathological observations suggesting marked nephroprotective potential. The anti-toxic effect of this plant may in part be mediated through the chemical constituents of the plant. The plant, Hippocratea africana possesses anti-toxicant properties which can be exploited in the treatment of doxorubicin related toxicities.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135619320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Primary and Secondary Metabolites of Apis cerana Honey using FTIR-ATR Diamond Spectroscopy and Their Botanical Origin","authors":"Tiffany Hanik Lestari, Ratna Susandarini","doi":"10.14421/biomedich.2023.122.467-475","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.467-475","url":null,"abstract":"Apis cerana Fab. is one of the popular honeybees species among beekeepers in Indonesia. This species is easy to care for and produces valuable honey products. Honey from A. cerana is abundantly available in traditional and modern markets in Indonesia. The purpose of this study was to identify the primary and secondary metabolites in the honey produced by A. cerana using FTIR-ATR Diamond spectroscopy. Twelve samples of honey from three provinces in Java Island were used in this study. In general, all honey samples contained protein, carbohydrate, water, alcohol, cellulose, alkaloid, tannin, and flavonoid. Variation on primary and secondary metabolites in honey samples was strongly affected by the botanical origin, geographical origin, and the local condition around beekeeping areas where the honeycombs were placed.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135875907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proximate and Mineral Composition of Atlantic Mackerel (Scomber scombrus) and Atlantic Horse Mackerel (Trachurus trachurus)","authors":"Joseph Adaviruku Sanni, Grace Omayoza Sanni, Rufus Ranmilowo Awoniyi, Remi Osanyinlusi, Yvonne Ego Richards","doi":"10.14421/biomedich.2023.122.457-461","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.457-461","url":null,"abstract":"Atlantic mackerel (Scomber scombrus) and Atlantic horse mackerel (Trachurus trachurus), locally known as kote, are fishery species consumed in Nigeria due to their high nutritional values. This research determined the nutritional composition of the local dried fish, Scomber scombrus and Trachurus trachurus. Results for Scomber scombrus shows the mean value of the moisture, ash, crude fat, crude fiber, and crude protein contents in percent (%) as: 5.260.00, 5.200.10, 35.600.00, 2.900.10 and 46.300.01 respectively. For Trachurus trachurus, the moisture, ash, crude fat, crude fiber, and crude protein contents in percent (%) were 9.520.00, 32.260.01, 24.140.00, 11.910.85 and 40.950.00 respectively. The mineral composition of Scomber scombrus was as follows: Sodium (Na) had the highest mineral composition with 78.90 mg/100g, followed by magnesium (Mg) with 15.90 mg/100g, manganese (Mn) with 0.86 mg/100g, zinc (Zn) with 0.282 mg/100g, and iron (Fe) with 0.10 mg/100g. Trachurus trachurus has magnesium (Mg) at 27.00 mg/100g as its highest mineral composition, followed by sodium (Na) at 22.50 mg/100g, zinc (Zn), iron (Fe) at 0.17 mg/100g, and manganese (Mn) at 0.09 mg/100g. It is concluded from the study, that Scomber scombrus and Trachurus trachurus are good sources of essential nitrates, fat, proteins containing essential amino acids, and other micronutrients that are beneficial to human health.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135165120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Medicinal Plants and Their Utilization by Community in Kendal Village, Kendal Sub-district","authors":"Aghnia Rahmi Hanum, Erna Wijayanti","doi":"10.14421/biomedich.2023.122.463-466","DOIUrl":"https://doi.org/10.14421/biomedich.2023.122.463-466","url":null,"abstract":"Traditional medicine is a cultural heritage from ancestors deeply rooted in the nation's heritage; therefore, its use is still based on spoken and written experience from generation to generation. Even though most people have turned to modern medicine, some still use these medicinal plants as ingredients for medicine, food, and other processed consumption. This study aims to identify the types of medicinal plants found in Kendal village and how to use them, obtain them, and then transform them into effective medications. This study employs qualitative descriptive methodologies. Observation and interviews are employed to collect data. Based on the results of community interviews, it was determined that many Kendal village residents continue to use plants to treat various diseases. The plant parts utilized are rhizomes, leaves, and stems. This medicinal plant has various uses, ranging from direct consumption to boiling.","PeriodicalId":8882,"journal":{"name":"Biology, Medicine, & Natural Product Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135165119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}