Pub Date : 2019-04-14DOI: 10.1364/BODA.2019.DT1B.7
Matan Benyamin, H. Genish, R. Califa, N. Ozana, Ariel Schwartz, Z. Zalevsky
A novel method for non-contact detection of photoacoustic signals is presented and experimentally demonstrated. The approach is based on time varying speckle pattern analysis and suggests a more robust alternative for interferometric and refractometric solutions.
{"title":"Remote Detection of Photoacoustic Signals using Time Varying Speckle Patterns","authors":"Matan Benyamin, H. Genish, R. Califa, N. Ozana, Ariel Schwartz, Z. Zalevsky","doi":"10.1364/BODA.2019.DT1B.7","DOIUrl":"https://doi.org/10.1364/BODA.2019.DT1B.7","url":null,"abstract":"A novel method for non-contact detection of photoacoustic signals is presented and experimentally demonstrated. The approach is based on time varying speckle pattern analysis and suggests a more robust alternative for interferometric and refractometric solutions.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"63 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84856725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/brain.2019.bw1a.1
M. Balberg, R. Shechter
Acousto-optic sensing, using ultrasound-modulated light in live tissue, enables non-invasive, continuous monitoring of blood flow in the brain. Preclinical and clinical data demonstrate agreement with other modalities for blood flow sensing and its benefits.
{"title":"Acousto Optics for Cerebral Blood Flow Monitoring","authors":"M. Balberg, R. Shechter","doi":"10.1364/brain.2019.bw1a.1","DOIUrl":"https://doi.org/10.1364/brain.2019.bw1a.1","url":null,"abstract":"Acousto-optic sensing, using ultrasound-modulated light in live tissue, enables non-invasive, continuous monitoring of blood flow in the brain. Preclinical and clinical data demonstrate agreement with other modalities for blood flow sensing and its benefits.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87177973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/boda.2019.dw1b.7
Zhencong Xiong, J. Melzer, Jacob Garan, E. Mcleod
Lens-free holographic microscopy offers sub-micron resolution over a field-of-view >20 mm2, making it a suitable biomedical imaging and sensing platform. We devised a sparsity-promoting method, which enhances SNR by ∼ 8 dB compared to traditional methods.
{"title":"Optimized Reconstruction for Sparse and Small Targets in Lens-free Holographic Microscopy","authors":"Zhencong Xiong, J. Melzer, Jacob Garan, E. Mcleod","doi":"10.1364/boda.2019.dw1b.7","DOIUrl":"https://doi.org/10.1364/boda.2019.dw1b.7","url":null,"abstract":"Lens-free holographic microscopy offers sub-micron resolution over a field-of-view >20 mm2, making it a suitable biomedical imaging and sensing platform. We devised a sparsity-promoting method, which enhances SNR by ∼ 8 dB compared to traditional methods.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"12 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85990054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To utilize optical techniques for bio-medical applications, e.g. disease diagnostics, the data needs to be analyzed using machine learning. This translation requires automatic data pipelines presented in this contribution for selected application.
{"title":"Machine Learning Methods for Spectral and Image Data","authors":"T. Bocklitz","doi":"10.1364/omp.2019.ot3d.1","DOIUrl":"https://doi.org/10.1364/omp.2019.ot3d.1","url":null,"abstract":"To utilize optical techniques for bio-medical applications, e.g. disease diagnostics, the data needs to be analyzed using machine learning. This translation requires automatic data pipelines presented in this contribution for selected application.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85278119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/boda.2019.jt4a.26
J. Sudyka, Michat Hamkato, M. Wojtkowski
We present imaging technique based on single-pixel camera concept. Method encompasses two-dimensional image acquisition with possible data compression and only singular photodiode needed. Our system may become important tool for modern microscopy.
{"title":"Application of single-pixel camera for imaging in turbid media","authors":"J. Sudyka, Michat Hamkato, M. Wojtkowski","doi":"10.1364/boda.2019.jt4a.26","DOIUrl":"https://doi.org/10.1364/boda.2019.jt4a.26","url":null,"abstract":"We present imaging technique based on single-pixel camera concept. Method encompasses two-dimensional image acquisition with possible data compression and only singular photodiode needed. Our system may become important tool for modern microscopy.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"69 5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89120781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/brain.2019.bm3a.6
Wilson R. Adams, A. I. Borrachero-Conejo, Manqing Wang, E. Saracino, Tamara Posati, R. Zamboni, M. Caprini, G. P. Nicchia, E. Jansen, V. Benfenati, A. Mahadevan-Jansen
To begin understanding how pulsed infrared light modulates brain tissues in vivo, we explored its effects on isolated cortical astrocytes in vitro. Pulsed IR light may be a useful tool to study glial physiology.
{"title":"Pulsed Infrared Light Evokes Astrocytic Calcium Signaling in a Label-Free Format","authors":"Wilson R. Adams, A. I. Borrachero-Conejo, Manqing Wang, E. Saracino, Tamara Posati, R. Zamboni, M. Caprini, G. P. Nicchia, E. Jansen, V. Benfenati, A. Mahadevan-Jansen","doi":"10.1364/brain.2019.bm3a.6","DOIUrl":"https://doi.org/10.1364/brain.2019.bm3a.6","url":null,"abstract":"To begin understanding how pulsed infrared light modulates brain tissues in vivo, we explored its effects on isolated cortical astrocytes in vitro. Pulsed IR light may be a useful tool to study glial physiology.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90941493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/BRAIN.2019.BW1A.4
Mitchell B. Robinson, S. Carp, D. Tamborini, D. Boas, M. Franceschini
Diffuse correlation spectroscopy (DCS) is a technique that has traditionally required low noise, single photo counting detectors. By utilizing an interferometric approach, we show that these hardware conditions can be relaxed.
{"title":"Interrogation of sample dynamics using interferometric diffuse correlation spectroscopy","authors":"Mitchell B. Robinson, S. Carp, D. Tamborini, D. Boas, M. Franceschini","doi":"10.1364/BRAIN.2019.BW1A.4","DOIUrl":"https://doi.org/10.1364/BRAIN.2019.BW1A.4","url":null,"abstract":"Diffuse correlation spectroscopy (DCS) is a technique that has traditionally required low noise, single photo counting detectors. By utilizing an interferometric approach, we show that these hardware conditions can be relaxed.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78683659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/boda.2019.dm4b.3
Cheng Gong, N. Kulkarni, Wenbin Zhu, Christopher D. Nguyen, C. Curiel-Lewandrowski, Dongkyun Kang
We developed a low-cost, high-speed near infrared confocal microscope. Material cost was approximately $5,000. In vivo confocal images of human skin acquired at 203 frame/sec clearly visualized cellular features, including keratinocytes and melanocytes.
{"title":"Low-cost, high-speed near-infrared confocal microscope","authors":"Cheng Gong, N. Kulkarni, Wenbin Zhu, Christopher D. Nguyen, C. Curiel-Lewandrowski, Dongkyun Kang","doi":"10.1364/boda.2019.dm4b.3","DOIUrl":"https://doi.org/10.1364/boda.2019.dm4b.3","url":null,"abstract":"We developed a low-cost, high-speed near infrared confocal microscope. Material cost was approximately $5,000. In vivo confocal images of human skin acquired at 203 frame/sec clearly visualized cellular features, including keratinocytes and melanocytes.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83565794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Barton, Jennifer W. Koevary, P. Rice, T. Sawyer
We show that multispectral fluorescence imaging, optical coherence tomography, and multispectral microscopy differentiates normal, cancer, and benign ovary and fallopian tube tissue in a mouse model and human tissue samples.
{"title":"Endogenous and exogenous contrast mechanisms for detection of ovarian cancer","authors":"J. Barton, Jennifer W. Koevary, P. Rice, T. Sawyer","doi":"10.1364/omp.2019.ot2d.2","DOIUrl":"https://doi.org/10.1364/omp.2019.ot2d.2","url":null,"abstract":"We show that multispectral fluorescence imaging, optical coherence tomography, and multispectral microscopy differentiates normal, cancer, and benign ovary and fallopian tube tissue in a mouse model and human tissue samples.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88293725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-04-14DOI: 10.1364/BODA.2019.DW1B.6
Hoang Nguyen, Wei-Chuan Shih
We report smartphone nano-colorimetry (SNC) for mobile and multiplex detection and quantitation of lead and mercury ions in drinking water. The detection limit is below EPA action levels set for both metal ions.
{"title":"Multiplex sensing of lead and mercury in drinking water using smartphone nano-colorimetry","authors":"Hoang Nguyen, Wei-Chuan Shih","doi":"10.1364/BODA.2019.DW1B.6","DOIUrl":"https://doi.org/10.1364/BODA.2019.DW1B.6","url":null,"abstract":"We report smartphone nano-colorimetry (SNC) for mobile and multiplex detection and quantitation of lead and mercury ions in drinking water. The detection limit is below EPA action levels set for both metal ions.","PeriodicalId":8973,"journal":{"name":"Biophotonics Congress: Optics in the Life Sciences Congress 2019 (BODA,BRAIN,NTM,OMA,OMP)","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88314361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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