首页 > 最新文献

International neuropsychiatric disease journal最新文献

英文 中文
Post Traumatic Epilepsy with Sequel of Frontal Contusion and Spontaneous Regression of Extradural Hematoma; Clinical Case and Review of the Literature 外伤性癫痫伴额挫伤及硬膜外血肿自发性消退临床病例及文献复习
Pub Date : 2022-12-31 DOI: 10.9734/indj/2022/v18i4361
J. Fondop, Koagne Foagouo, Dikongue Dikongue Fred, A. Faustin, D. C. Alain, M. Mathieu, Fuentes Stéphane, Djientcheu Vincent de Paul, S. Fuentes
Post traumatic epilepsy are frequent complications of moderate and severe head injuries, they are found in hemorrhagic contusions and hematomas. Several isolated or associated mechanisms are involved in the occurrence of these convulsions (increased inflammatory markers, neuronal cell death, altered blood-brain barrier, changes in astrocytes, and glucose metabolism dysregulation changes in synaptic abundance and function).The first attacks can occur more than 2 years after the head trauma or after cranial surgery. Preventive treatment does not change the course of the disease. Treatment with Valproate and levetiracetam were also compared to phenytoin and no benefit was found in recovery. The particularity of our patient is the severe head trauma, with regressive frontal contusion with secular lesions, followed by the appearance at nearly three and a half months of the trauma of a fronto-parietal extradural hematoma with mass effect which resolved spontaneously. Two and three years after the trauma, he developed generalized epilepsy, suggesting post-traumatic epilepsy following the sequelae of the hemorrhagic contusion or the extradural hematoma, or the sequelae of these associated lesions. These seizures were treated with sodium valproate. This clinical case challenges clinicians to monitor in severe head injuries the occurrence of complications such as epilepsy that can occur beyond 2 years.
外伤后癫痫是中重度颅脑损伤的常见并发症,常见于出血性挫伤和血肿。这些抽搐的发生涉及几个独立或相关的机制(炎症标志物增加、神经元细胞死亡、血脑屏障改变、星形胶质细胞的变化以及突触丰度和功能的葡萄糖代谢失调变化)。第一次发作可能发生在头部创伤后2年以上或颅骨手术后。预防性治疗不会改变疾病的进程。丙戊酸钠和左乙拉西坦的治疗也与苯妥英钠进行了比较,没有发现对恢复有任何益处。我们患者的特殊性是严重的头部创伤,伴有退行性额挫伤和长期病变,随后在创伤近三个半月时出现额顶叶硬膜外血肿,肿块效应自行消退。创伤后两三年,他发展为全身性癫痫,这表明创伤后癫痫是出血性挫伤或硬膜外血肿的后遗症,或这些相关病变的后遗症。这些癫痫发作用丙戊酸钠治疗。这一临床病例挑战了临床医生在严重头部损伤中监测并发症(如癫痫)的发生,这些并发症可能发生在2年后。
{"title":"Post Traumatic Epilepsy with Sequel of Frontal Contusion and Spontaneous Regression of Extradural Hematoma; Clinical Case and Review of the Literature","authors":"J. Fondop, Koagne Foagouo, Dikongue Dikongue Fred, A. Faustin, D. C. Alain, M. Mathieu, Fuentes Stéphane, Djientcheu Vincent de Paul, S. Fuentes","doi":"10.9734/indj/2022/v18i4361","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i4361","url":null,"abstract":"Post traumatic epilepsy are frequent complications of moderate and severe head injuries, they are found in hemorrhagic contusions and hematomas. Several isolated or associated mechanisms are involved in the occurrence of these convulsions (increased inflammatory markers, neuronal cell death, altered blood-brain barrier, changes in astrocytes, and glucose metabolism dysregulation changes in synaptic abundance and function).The first attacks can occur more than 2 years after the head trauma or after cranial surgery. Preventive treatment does not change the course of the disease. Treatment with Valproate and levetiracetam were also compared to phenytoin and no benefit was found in recovery. \u0000The particularity of our patient is the severe head trauma, with regressive frontal contusion with secular lesions, followed by the appearance at nearly three and a half months of the trauma of a fronto-parietal extradural hematoma with mass effect which resolved spontaneously. Two and three years after the trauma, he developed generalized epilepsy, suggesting post-traumatic epilepsy following the sequelae of the hemorrhagic contusion or the extradural hematoma, or the sequelae of these associated lesions. These seizures were treated with sodium valproate. This clinical case challenges clinicians to monitor in severe head injuries the occurrence of complications such as epilepsy that can occur beyond 2 years.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44656395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mental and Physical Well Being in Prisoners 囚犯的身心健康
Pub Date : 2022-12-31 DOI: 10.9734/indj/2022/v18i4360
Brandon Presley, Kimberly Morton Cuthrell
Global health attention is necessary to improve the prison population mental and physical health because limited public health ramifications and inmates’ psychological effects impose many strains on community preventive measures and prison rehabilitation. Though some prisoners are  younger than the general population, the jail population often has the worse health. Many have considerable mental and physical health needs as a result of social and economic poverty. Since many prisoners have histories of tobacco use and alcohol or drugs, many of these risk patterns  result in addictions that are tied to unhealthy  lifestyles. Prior contact with mental health, substance use or medical services  typically was very limited or absent due to lack of access to treatment, diminished resources, barriers for the uninsured and underserved, financial stability to afford care, stigma, or reluctance to focus on self-care. There are certain mental health disorders and infectious diseases that are prevalent in prisoners and should be addressed. Many prisoners have serious, debilitating mental and physical conditions that go untreated or undiagnosed while they are incarcerated. Prior to being incarcerated, If crime and incarceration are to be decreased and rehabilitative efforts are increased to deter re-incarceration, preventive measures are necessary that include community mental and medical services accessibility and affordability while availability of such services are provided in prison and coordination of care of evidence-based therapy and infection-control strategies are highly recommended before the inmate returns to the community. This review covers most common mental and physical health issues and their management for inmates because few research has explored how having a mental health disorder compound with a physical ailment affects an inmate’s behavior while advocating for human rights-informed strategies for the treatment of people in the criminal justice system.
全球卫生关注对于改善监狱人口的身心健康是必要的,因为有限的公共卫生影响和囚犯的心理影响给社区预防措施和监狱改造带来了许多压力。尽管一些囚犯比普通囚犯年轻,但监狱囚犯的健康状况往往更差。由于社会和经济贫困,许多人有相当大的身心健康需求。由于许多囚犯有吸烟、酗酒或吸毒的历史,其中许多风险模式会导致与不健康生活方式有关的成瘾。由于缺乏治疗、资源减少、没有保险和服务不足者的障碍、负担得起护理的经济稳定、耻辱感或不愿专注于自我护理,先前与心理健康、药物使用或医疗服务的接触通常非常有限或缺乏。囚犯中普遍存在某些精神健康障碍和传染病,应予以解决。许多囚犯在监禁期间都有严重的、使人衰弱的精神和身体状况,得不到治疗或诊断。在被监禁之前,如果要减少犯罪和监禁,并加大康复力度以阻止再次监禁,预防措施是必要的,包括社区精神和医疗服务的可及性和可负担性,同时在监狱中提供此类服务,并强烈建议在囚犯返回社区之前协调循证治疗和感染控制策略的护理。这篇综述涵盖了最常见的心理和身体健康问题及其对囚犯的管理,因为很少有研究探讨患有身体疾病的心理健康障碍复合物如何影响囚犯的行为,同时倡导在刑事司法系统中采用人权知情策略来对待人。
{"title":"Mental and Physical Well Being in Prisoners","authors":"Brandon Presley, Kimberly Morton Cuthrell","doi":"10.9734/indj/2022/v18i4360","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i4360","url":null,"abstract":"Global health attention is necessary to improve the prison population mental and physical health because limited public health ramifications and inmates’ psychological effects impose many strains on community preventive measures and prison rehabilitation. Though some prisoners are  younger than the general population, the jail population often has the worse health. Many have considerable mental and physical health needs as a result of social and economic poverty. Since many prisoners have histories of tobacco use and alcohol or drugs, many of these risk patterns  result in addictions that are tied to unhealthy  lifestyles. Prior contact with mental health, substance use or medical services  typically was very limited or absent due to lack of access to treatment, diminished resources, barriers for the uninsured and underserved, financial stability to afford care, stigma, or reluctance to focus on self-care. There are certain mental health disorders and infectious diseases that are prevalent in prisoners and should be addressed. Many prisoners have serious, debilitating mental and physical conditions that go untreated or undiagnosed while they are incarcerated. Prior to being incarcerated, If crime and incarceration are to be decreased and rehabilitative efforts are increased to deter re-incarceration, preventive measures are necessary that include community mental and medical services accessibility and affordability while availability of such services are provided in prison and coordination of care of evidence-based therapy and infection-control strategies are highly recommended before the inmate returns to the community. This review covers most common mental and physical health issues and their management for inmates because few research has explored how having a mental health disorder compound with a physical ailment affects an inmate’s behavior while advocating for human rights-informed strategies for the treatment of people in the criminal justice system.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46964883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Substance Use Disorder: A Case of Alcohol Withdrawal in a 40 Year Old Man 物质使用障碍:一例40岁男性酒精戒断
Pub Date : 2022-12-30 DOI: 10.9734/indj/2022/v18i4359
C. Elendu, Chiagozie P. Ayabazu, Abasi-Okot A. Udoyen, Nnenna O. Kalu-Udeh, Olisa S. Okabekwa, Rachel E. Dada, Precious A. Ante, Emmanuel O. Egbunu, Michael C. Eze, Geraldine C. Okafor, Joy M. Enyong, Blessing N. Bassey, Joy H. Avong, Anietienteabasi O. Okongko
Alcohol withdrawal is a clinical state characterized by symptoms such as tremors, tachycardia, sweating, nausea and vomiting, headache, malaise, insomnia, grand mal convulsions amongst others. Patients typically present acutely with a history of recent cessation or reduction of heavy alcohol use after a long period of repeated, persistent use. It may feature perceptual disturbances such as illusions or hallucinations. It may present with delirium in a condition known as delirium tremens, which typically occurs after recent cessation or reduction of very heavy alcohol use in patients with a long-standing history of alcohol dependence syndrome, who may also have coexisting medical conditions. We herein report a case of a 40 year old man, with a 12-month history of persistent alcohol use, who presented with classical symptoms of alcohol withdrawal including inability to sleep, excessive sweating, tachycardia, vomiting, and hallucinations. There is no associated history of convulsions or co-morbid medical conditions. Features of this case are discussed, as well as evaluation and treatment of alcohol withdrawal.
酒精戒断是一种临床状态,其特征是震颤、心动过速、出汗、恶心和呕吐、头痛、不适、失眠、大痉挛等症状。患者通常急性表现为在长期反复、持续使用酒精后近期停止或减少大量酒精使用的历史。它可能以错觉或幻觉等知觉障碍为特征。它可能表现为谵妄,称为震颤谵妄,通常发生在有长期酒精依赖综合征病史的患者最近停止或减少大量饮酒后,这些患者也可能同时存在其他疾病。我们在此报告一例40岁男性,有12个月的持续酒精使用史,他表现出典型的酒精戒断症状,包括无法入睡,出汗过多,心动过速,呕吐和幻觉。没有相关的惊厥病史或合并症。本病例的特点进行了讨论,以及评估和治疗的酒精戒断。
{"title":"Substance Use Disorder: A Case of Alcohol Withdrawal in a 40 Year Old Man","authors":"C. Elendu, Chiagozie P. Ayabazu, Abasi-Okot A. Udoyen, Nnenna O. Kalu-Udeh, Olisa S. Okabekwa, Rachel E. Dada, Precious A. Ante, Emmanuel O. Egbunu, Michael C. Eze, Geraldine C. Okafor, Joy M. Enyong, Blessing N. Bassey, Joy H. Avong, Anietienteabasi O. Okongko","doi":"10.9734/indj/2022/v18i4359","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i4359","url":null,"abstract":"Alcohol withdrawal is a clinical state characterized by symptoms such as tremors, tachycardia, sweating, nausea and vomiting, headache, malaise, insomnia, grand mal convulsions amongst others. Patients typically present acutely with a history of recent cessation or reduction of heavy alcohol use after a long period of repeated, persistent use. It may feature perceptual disturbances such as illusions or hallucinations. It may present with delirium in a condition known as delirium tremens, which typically occurs after recent cessation or reduction of very heavy alcohol use in patients with a long-standing history of alcohol dependence syndrome, who may also have coexisting medical conditions. We herein report a case of a 40 year old man, with a 12-month history of persistent alcohol use, who presented with classical symptoms of alcohol withdrawal including inability to sleep, excessive sweating, tachycardia, vomiting, and hallucinations. There is no associated history of convulsions or co-morbid medical conditions. Features of this case are discussed, as well as evaluation and treatment of alcohol withdrawal.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43042224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Unexpected Headache: Pituitary Apoplexy in a Patient Admitted with Diabetes Ketoacidosis (DKA) 意外头痛:1例糖尿病酮症酸中毒(DKA)患者垂体卒中
Pub Date : 2022-12-29 DOI: 10.9734/indj/2022/v18i4358
Hanadi Alnageeb, Amal Al Maeeni, Ashraf Alakkad, A. Qaidy, R. Bhat
Background: Pituitary apoplexy is a clinical problem resulting from abrupt pituitary ischemia or hemorrhage. A small proportion of pituitary adenomas manifest as an apoplectic crisis, with pan hypopituitarism, vomiting, nausea, headache, ophthalmoplegia, and visual impairment being the most common symptoms. Case Report: A 32-year-old diabetic Asian male presented to the emergency department with symptoms of polyuria, polydipsia, persistent vomiting, and diffused abdominal pain. He also reported a recent fever and severe headache, as well as self-limited episodes of blurring of vision and diplopia three months prior. Upon admission, his vitals were stable and he was fully conscious and oriented, though irritable and anxious. On examination, he was found to have third cranial nerve palsy and a dilated pupil with no light reflex. Laboratory tests revealed diabetic ketoacidosis (DKA). A CT scan of the brain revealed a possible invasive pituitary macro adenoma and the patient was referred for further evaluation. He also tested positive for COVID-19. Treatment for DKA was initiated and an MRI scan was scheduled for further evaluation. However, the patient's condition worsened and he was transferred to the ICU, where he was intubated and an MRI indicated a hemorrhagic mass in the pituitary gland. The patient was diagnosed with pituitary apoplexy, and he also received treatment with antibiotics and antiviral medication for suspected encephalitis. Conclusion: Pituitary apoplexy is a serious condition that requires immediate evaluation and treatment. It can cause permanent damage or death if left untreated. Treatment options include surgery and conservative management with frequent monitoring.
背景:垂体卒中是一种由垂体突然缺血或出血引起的临床问题。一小部分垂体腺瘤表现为中风危象,最常见的症状是泛垂体功能减退、呕吐、恶心、头痛、眼麻痹和视力损害。病例报告:一名32岁亚洲男性糖尿病患者以多尿、烦渴、持续呕吐和弥漫性腹痛等症状就诊于急诊科。他还报告最近发烧和严重头痛,三个月前出现视力模糊和复视的自限性发作。入院时,他的生命体征稳定,意识完全清醒,定向能力强,但易怒和焦虑。经检查,发现他有第三脑神经麻痹,瞳孔扩大,无光反射。实验室检查显示为糖尿病酮症酸中毒。脑部CT扫描显示可能为侵袭性垂体大腺瘤,患者接受进一步检查。他的COVID-19检测结果也呈阳性。开始治疗DKA,并计划进行MRI扫描以进一步评估。然而,病人的病情恶化,他被转移到重症监护室,在那里他插管,核磁共振成像显示脑垂体出血块。患者被诊断为垂体性中风,并因疑似脑炎接受抗生素和抗病毒药物治疗。结论:垂体卒中是一种严重的疾病,需要立即评估和治疗。如果不及时治疗,可能会导致永久性损伤或死亡。治疗方案包括手术和保守治疗并经常监测。
{"title":"An Unexpected Headache: Pituitary Apoplexy in a Patient Admitted with Diabetes Ketoacidosis (DKA)","authors":"Hanadi Alnageeb, Amal Al Maeeni, Ashraf Alakkad, A. Qaidy, R. Bhat","doi":"10.9734/indj/2022/v18i4358","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i4358","url":null,"abstract":"Background: Pituitary apoplexy is a clinical problem resulting from abrupt pituitary ischemia or hemorrhage. A small proportion of pituitary adenomas manifest as an apoplectic crisis, with pan hypopituitarism, vomiting, nausea, headache, ophthalmoplegia, and visual impairment being the most common symptoms. \u0000Case Report: A 32-year-old diabetic Asian male presented to the emergency department with symptoms of polyuria, polydipsia, persistent vomiting, and diffused abdominal pain. He also reported a recent fever and severe headache, as well as self-limited episodes of blurring of vision and diplopia three months prior. Upon admission, his vitals were stable and he was fully conscious and oriented, though irritable and anxious. On examination, he was found to have third cranial nerve palsy and a dilated pupil with no light reflex. Laboratory tests revealed diabetic ketoacidosis (DKA). A CT scan of the brain revealed a possible invasive pituitary macro adenoma and the patient was referred for further evaluation. He also tested positive for COVID-19. Treatment for DKA was initiated and an MRI scan was scheduled for further evaluation. However, the patient's condition worsened and he was transferred to the ICU, where he was intubated and an MRI indicated a hemorrhagic mass in the pituitary gland. The patient was diagnosed with pituitary apoplexy, and he also received treatment with antibiotics and antiviral medication for suspected encephalitis. \u0000Conclusion: Pituitary apoplexy is a serious condition that requires immediate evaluation and treatment. It can cause permanent damage or death if left untreated. Treatment options include surgery and conservative management with frequent monitoring.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47664829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Study of Psychological Impact of COVID-19 on Healthcare and Non-Healthcare Workers Using WHO-QOL BREF and PHQ-9 Scale- An Indian Nationwide Cross-sectional Study 使用WHO-QOL BREF和PHQ-9量表对COVID-19对医护人员和非医护人员心理影响的比较研究——一项印度全国性横断面研究
Pub Date : 2022-12-26 DOI: 10.9734/indj/2022/v18i4357
Akhil Arun, A. M, Bulla Karunya, Thendral R., B. Milton, Vinod K. Matthew
Background: The world population has been greatly affected by the Sars-Cov-2 pandemic and the related financial, civil, psychological and mental health consequences. Considering the significance of QOL, it is imperative to consider the effects of the pandemic on the population. The study was designed to compare the psychological Impact of COVID-19 on healthcare and non- healthcare workers during COVID-19 pandemic. Materials and Methods: A cross-sectional survey was conducted among healthcare and non-healthcare workers and a structured questionnaire was circulated in goggle forms via emails and social networking sites. Results: The mean score for four QOL domains was 58.82 ±15.56, 56.45 ±15.52, 59.08 ±19.03 and 51.42 ±15.51, respectively. Among participants, (31.3%) had Minimal Depression,(33.4%) Mild depression, (24.7%) Moderate depression and (8.8%) had moderate-severe depression .Healthcare workers were found to be more depressed (34%) at a moderate level of depression and (11%) at severe depression while (11%) of non-Healthcare workers show moderate depression and 12 (5%) show moderately severe depression. Conclusions: The study depicted the detrimental impact of the pandemic on the population, with healthcare workers being more affected by the pandemic and this study calls for use of appropriate psychological intervention to address the mental health needs of the population.
背景:世界人口受到严重急性呼吸系统综合征冠状病毒2型疫情及其相关的金融、民事、心理和心理健康后果的严重影响。考虑到生活质量的重要性,必须考虑疫情对人群的影响。该研究旨在比较新冠肺炎对新冠肺炎大流行期间医护人员和非医护人员的心理影响。材料和方法:在医护人员和非医护人员中进行了一项横断面调查,并通过电子邮件和社交网站以护目镜的形式分发了一份结构化问卷。结果:四个生活质量领域的平均得分分别为58.82±15.56、56.45±15.52、59.08±19.03和51.42±15.51。在参与者中,(31.3%)患有轻度抑郁症,(33.4%)患有轻度抑郁,(24.7%)患有中度抑郁,(8.8%)患有中度-重度抑郁。发现医护人员在中度抑郁时更抑郁(34%),在重度抑郁时更沮丧(11%),而(11%)非医护人员表现出中度抑郁,12人(5%)表现出中度-重度抑郁症。结论:这项研究描述了疫情对人群的有害影响,医护人员受到疫情的影响更大,这项研究呼吁使用适当的心理干预来满足人群的心理健康需求。
{"title":"Comparative Study of Psychological Impact of COVID-19 on Healthcare and Non-Healthcare Workers Using WHO-QOL BREF and PHQ-9 Scale- An Indian Nationwide Cross-sectional Study","authors":"Akhil Arun, A. M, Bulla Karunya, Thendral R., B. Milton, Vinod K. Matthew","doi":"10.9734/indj/2022/v18i4357","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i4357","url":null,"abstract":"Background: The world population has been greatly affected by the Sars-Cov-2 pandemic and the related financial, civil, psychological and mental health consequences. Considering the significance of QOL, it is imperative to consider the effects of the pandemic on the population. The study was designed to compare the psychological Impact of COVID-19 on healthcare and non- healthcare workers during COVID-19 pandemic. \u0000Materials and Methods: A cross-sectional survey was conducted among healthcare and non-healthcare workers and a structured questionnaire was circulated in goggle forms via emails and social networking sites. \u0000Results: The mean score for four QOL domains was 58.82 ±15.56, 56.45 ±15.52, 59.08 ±19.03 and 51.42 ±15.51, respectively. Among participants, (31.3%) had Minimal Depression,(33.4%) Mild depression, (24.7%) Moderate depression and (8.8%) had moderate-severe depression .Healthcare workers were found to be more depressed (34%) at a moderate level of depression and (11%) at severe depression while (11%) of non-Healthcare workers show moderate depression and 12 (5%) show moderately severe depression. \u0000Conclusions: The study depicted the detrimental impact of the pandemic on the population, with healthcare workers being more affected by the pandemic and this study calls for use of appropriate psychological intervention to address the mental health needs of the population.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43685966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Deep Brain Stimulation-Emerging Indications and Newer Techniques: A Current Perspective 脑深部刺激-新出现的适应症和新技术:当前的观点
Pub Date : 2022-12-26 DOI: 10.9734/indj/2022/v18i3356
Fayrouz Moidu, Sujith Ovallath
Deep brain stimulation (DBS) is in clinical use for more than three decades and its indications are ever expanding. Conventionally DBS is used in the treatment of Parkinson’s disease (PD), tremor and dystonia, and has been approved by FDA. It has been tried in several other indications with encouraging results. Recently a DBS device has been approved for use in intractable epilepsy. DBS is giving promising results for use in obesity, trigeminal vascular cephalalgias, and Tourette syndrome and post stroke rehabilitation. Many psychiatric conditions like depression, obsessive compulsive disorder, anorexia nervosa and substance abuse can be controlled with DBS when conventional medical treatment fails to relieve the symptoms. Newer techniques in DBS like directional leads, variable frequency stimulation, newer target identifications, Newer MRI compatible devices, remote programming, newer DBS recording electrodes that can be used in finding out the pathophysiology of disease is also discussed.
脑深部电刺激(DBS)的临床应用已有三十多年,其适应症也在不断扩大。DBS通常用于治疗帕金森病(PD)、震颤和肌张力障碍,并已获得FDA批准。它已经在其他几个适应症中进行了试验,取得了令人鼓舞的结果。最近,一种DBS装置被批准用于治疗顽固性癫痫。DBS在肥胖、三叉血管性脑痛、妥瑞特综合征和中风后康复方面的应用取得了可喜的结果。许多精神疾病,如抑郁症、强迫症、神经性厌食症和药物滥用,在传统医学治疗无法缓解症状时,可以用DBS来控制。DBS的新技术,如定向引线,变频刺激,新的目标识别,新的MRI兼容设备,远程编程,新的DBS记录电极,可用于发现疾病的病理生理学也进行了讨论。
{"title":"Deep Brain Stimulation-Emerging Indications and Newer Techniques: A Current Perspective","authors":"Fayrouz Moidu, Sujith Ovallath","doi":"10.9734/indj/2022/v18i3356","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i3356","url":null,"abstract":"Deep brain stimulation (DBS) is in clinical use for more than three decades and its indications are ever expanding. Conventionally DBS is used in the treatment of Parkinson’s disease (PD), tremor and dystonia, and has been approved by FDA. It has been tried in several other indications with encouraging results. Recently a DBS device has been approved for use in intractable epilepsy. DBS is giving promising results for use in obesity, trigeminal vascular cephalalgias, and Tourette syndrome and post stroke rehabilitation. Many psychiatric conditions like depression, obsessive compulsive disorder, anorexia nervosa and substance abuse can be controlled with DBS when conventional medical treatment fails to relieve the symptoms. Newer techniques in DBS like directional leads, variable frequency stimulation, newer target identifications, Newer MRI compatible devices, remote programming, newer DBS recording electrodes that can be used in finding out the pathophysiology of disease is also discussed.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48825506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anticonvulsant Activity of Some Medicinal Plants: A Review 部分药用植物抗惊厥活性研究进展
Pub Date : 2022-12-24 DOI: 10.9734/indj/2022/v18i3355
Felix Keneolisa Asogwa, Ugwu Obiora Celestine, Ali Ibeabuchi Jude
Epilepsy is a central nervous system (neurological) disorder characterized by a bizarre feelings, sensations, and behaviors. Muscle spasms, convulsions, and loss of consciousness occasionally from epileptic seizures. Neuronal dependent on neurotransmitters in the central nervous system. In this review, we discussed epilepsy and its therapies, placing particular emphasis on some medicinal plants and their mechanism of action. The majority of herbal remedies that are both tested for anticonvulsant activity and utilized in ethno medicine to treat epilepsy were reported. The findings demonstrate that active components extracted from medicinal plants can prevent and treat neuronal disorder.
癫痫是一种中枢神经系统(神经学)疾病,其特征是怪异的感觉、感觉和行为。癫痫发作时偶尔会引起肌肉痉挛、抽搐和意识丧失。神经元依赖于中枢神经系统中的神经递质。在这篇综述中,我们讨论了癫痫及其治疗,特别强调了一些药用植物及其作用机制。据报道,大多数草药都经过抗惊厥活性测试,并在民族医学中用于治疗癫痫。研究结果表明,从药用植物中提取的活性成分可以预防和治疗神经元疾病。
{"title":"Anticonvulsant Activity of Some Medicinal Plants: A Review","authors":"Felix Keneolisa Asogwa, Ugwu Obiora Celestine, Ali Ibeabuchi Jude","doi":"10.9734/indj/2022/v18i3355","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i3355","url":null,"abstract":"Epilepsy is a central nervous system (neurological) disorder characterized by a bizarre feelings, sensations, and behaviors. Muscle spasms, convulsions, and loss of consciousness occasionally from epileptic seizures. Neuronal dependent on neurotransmitters in the central nervous system. In this review, we discussed epilepsy and its therapies, placing particular emphasis on some medicinal plants and their mechanism of action. The majority of herbal remedies that are both tested for anticonvulsant activity and utilized in ethno medicine to treat epilepsy were reported. The findings demonstrate that active components extracted from medicinal plants can prevent and treat neuronal disorder.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45857822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional Psychiatry Integrated Framework: Exploration of Nutrition and Co-occurring Bipolar Disorder and Post-traumatic Stress Disorder 营养精神病学综合框架:营养与双相情感障碍和创伤后应激障碍共同发生的探索
Pub Date : 2022-12-21 DOI: 10.9734/indj/2022/v18i3354
Kimberly Morton Cuthrell
Nutritional psychiatry advancements are needed in understanding the effects of food nutrients on co-occurring psychiatric conditions particularly bipolar disorder and post-traumatic stress disorder (PTSD). Food nutrients contribute to the increase and decrease of symptoms in psychiatric conditions. Bipolar disorder and PTSD are frequently co-occurring and significantly impact moods, how the brain processes information, and psychological stressors. Individuals diagnosed with bipolar disorder and PTSD experience increased risks of suicide and are more likely to have unhealthy dietary habits. Understanding the appropriate nutrients to consume and avoid may contribute to promising outcomes for psychiatric conditions. Advancements in awareness of food nutrition are necessary to manage not only psychiatric conditions but also medical conditions. Omega-3 fatty acids, minerals (magnesium and zinc), pro-biotics, B vitamins, vitamins C and D, large neutral amino acids, specifically tryptophan and tyrosine, and branched-chained amino acids, antioxidants found in fruits and vegetables, and fatty acids have been linked to improved outcomes in the management of bipolar disorder and PTSD symptoms. Foods associated with poor prognosis have been linked to caffeine, alcohol, sugar, salt, processed foods, and artificial additives. This research contributes to the body of literature by exploring a link between food nutrients and bipolar disorder and PTSD because no known study has explored a co-occurring treatment intervention for such psychiatric conditions, and introduces the Nutritional Psychiatry Integrated Framework (NPIF)with a patient-centered focus which makes this research compelling. Advancements in understanding the effects of nutritional psychiatry associated with symptoms of bipolar disorder and PTSD may introduce innovative dietary and psychological treatment approaches.
营养精神病学的进步需要理解食物营养素对共同发生的精神疾病,特别是双相情感障碍和创伤后应激障碍(PTSD)的影响。食物营养有助于精神疾病症状的增加和减少。双相情感障碍和创伤后应激障碍经常同时发生,并显著影响情绪、大脑处理信息的方式和心理压力源。被诊断患有双相情感障碍和创伤后应激障碍的人自杀的风险更高,而且更有可能有不健康的饮食习惯。了解适当的营养摄入和避免可能有助于精神疾病的有希望的结果。提高对食物营养的认识不仅对管理精神疾病而且对管理医疗状况都是必要的。Omega-3脂肪酸、矿物质(镁和锌)、益生菌、B族维生素、维生素C和D、大量中性氨基酸,特别是色氨酸和酪氨酸、支链氨基酸、水果和蔬菜中的抗氧化剂以及脂肪酸,都与改善双相情感障碍和创伤后应激障碍症状的治疗结果有关。与预后不良有关的食物与咖啡因、酒精、糖、盐、加工食品和人工添加剂有关。本研究通过探索食物营养与双相情感障碍和创伤后应激障碍之间的联系,为文献做出了贡献,因为没有已知的研究探索了对此类精神疾病的共同发生的治疗干预,并以患者为中心介绍了营养精神病学综合框架(NPIF),这使得本研究引人注目。对与双相情感障碍和创伤后应激障碍症状相关的营养精神病学影响的理解的进步可能会引入创新的饮食和心理治疗方法。
{"title":"Nutritional Psychiatry Integrated Framework: Exploration of Nutrition and Co-occurring Bipolar Disorder and Post-traumatic Stress Disorder","authors":"Kimberly Morton Cuthrell","doi":"10.9734/indj/2022/v18i3354","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i3354","url":null,"abstract":"Nutritional psychiatry advancements are needed in understanding the effects of food nutrients on co-occurring psychiatric conditions particularly bipolar disorder and post-traumatic stress disorder (PTSD). Food nutrients contribute to the increase and decrease of symptoms in psychiatric conditions. Bipolar disorder and PTSD are frequently co-occurring and significantly impact moods, how the brain processes information, and psychological stressors. Individuals diagnosed with bipolar disorder and PTSD experience increased risks of suicide and are more likely to have unhealthy dietary habits. Understanding the appropriate nutrients to consume and avoid may contribute to promising outcomes for psychiatric conditions. Advancements in awareness of food nutrition are necessary to manage not only psychiatric conditions but also medical conditions. Omega-3 fatty acids, minerals (magnesium and zinc), pro-biotics, B vitamins, vitamins C and D, large neutral amino acids, specifically tryptophan and tyrosine, and branched-chained amino acids, antioxidants found in fruits and vegetables, and fatty acids have been linked to improved outcomes in the management of bipolar disorder and PTSD symptoms. Foods associated with poor prognosis have been linked to caffeine, alcohol, sugar, salt, processed foods, and artificial additives. This research contributes to the body of literature by exploring a link between food nutrients and bipolar disorder and PTSD because no known study has explored a co-occurring treatment intervention for such psychiatric conditions, and introduces the Nutritional Psychiatry Integrated Framework (NPIF)with a patient-centered focus which makes this research compelling. Advancements in understanding the effects of nutritional psychiatry associated with symptoms of bipolar disorder and PTSD may introduce innovative dietary and psychological treatment approaches.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42788088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determinants of Psychiatric Disorders among Residents of an Old Peoples’ Home in Southwestern Nigeria 尼日利亚西南部一家养老院居民精神疾病的决定因素
Pub Date : 2022-12-21 DOI: 10.9734/indj/2022/v18i3351
A. Oyewole, Olufunmilayo Olowokandi
Background: There are many challenges facing old people’s home care services in Nigeria and sub-Saharan Africa, with rates of functional impairment in older populations exceeding those in other parts of the globe. The prevalence of mental illness especially among the elderly has been projected to increase significantly in the years ahead. This study aimed to determine the factors associated with psychiatry disorders among inmates of old people home in Nigeria. Methods: This study was a cross-sectional design conducted among eighty-five respondents from inmates of old people’s homes, in Yaba, Lagos, selected using a purposive non-probability sampling technique. The instruments used include Structured Clinical Interview for DSM-IV and SCID-II Sociodemographic data were obtained via questionnaire and participation was by informed consent. Results: Of the total respondents, 38.8% were between the age category of 75-84 years. Only 2(2.4%) still had a spouse, 23(27.1%) were divorced and 58(68.2%) were widowers. Also, only 18(21.2%) had a personal source of income while most 76(89.4%) depend on financial support with the majority 36(42.4%) mainly from family and voluntary donations. It was observed that 75.3% had psychiatric morbidity among which 48.2% had Dementia, 16.5% had Schizophrenia and only 10.6% were diagnosed with Depression. Conclusion: This study lends credence to the fact that aging brings with it certain health challenges that may affect their well-being, especially in developing countries where socioeconomic ado poses significant setbacks in the care of the elderly. In view of the challenges identified among the residents of the old people’s home in Yaba; it is pertinent that efforts must be geared towards the establishment of qualitative medical facilities, especially for those with recognized physical or mental health challenges and poor socioeconomic status to cushion the effect of Mental illness.
背景:在尼日利亚和撒哈拉以南非洲,老年人的家庭护理服务面临许多挑战,老年人的功能损伤率超过了全球其他地区。预计今后几年,精神疾病的发病率,特别是老年人的发病率将显著增加。本研究旨在确定与尼日利亚养老院囚犯精神疾病相关的因素。方法:本研究是一项横断面设计,在拉各斯亚巴养老院的85名被调查者中进行,选择使用有目的的非概率抽样技术。使用的工具包括DSM-IV和SCID-II的结构化临床访谈,社会人口统计数据通过问卷调查获得,并通过知情同意参与。结果:75 ~ 84岁年龄组占38.8%。只有2人(2.4%)仍有配偶,23人(27.1%)离婚,58人(68.2%)丧偶。此外,只有18人(21.2%)有个人收入来源,76人(89.4%)依靠经济支持,其中36人(42.4%)主要来自家庭和自愿捐赠。75.3%的人患有精神疾病,其中48.2%的人患有痴呆症,16.5%的人患有精神分裂症,只有10.6%的人被诊断患有抑郁症。结论:这项研究证实了这样一个事实,即老龄化带来了某些健康挑战,可能会影响他们的福祉,特别是在发展中国家,那里的社会经济问题对老年人的护理造成了重大挫折。针对亚巴市老年之家居民面临的挑战;适当的是,必须努力建立高质量的医疗设施,特别是为那些有公认的身体或精神健康挑战和社会经济地位低下的人建立医疗设施,以缓解精神疾病的影响。
{"title":"Determinants of Psychiatric Disorders among Residents of an Old Peoples’ Home in Southwestern Nigeria","authors":"A. Oyewole, Olufunmilayo Olowokandi","doi":"10.9734/indj/2022/v18i3351","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i3351","url":null,"abstract":"Background: There are many challenges facing old people’s home care services in Nigeria and sub-Saharan Africa, with rates of functional impairment in older populations exceeding those in other parts of the globe. The prevalence of mental illness especially among the elderly has been projected to increase significantly in the years ahead. This study aimed to determine the factors associated with psychiatry disorders among inmates of old people home in Nigeria. \u0000Methods: This study was a cross-sectional design conducted among eighty-five respondents from inmates of old people’s homes, in Yaba, Lagos, selected using a purposive non-probability sampling technique. The instruments used include Structured Clinical Interview for DSM-IV and SCID-II Sociodemographic data were obtained via questionnaire and participation was by informed consent. \u0000Results: Of the total respondents, 38.8% were between the age category of 75-84 years. Only 2(2.4%) still had a spouse, 23(27.1%) were divorced and 58(68.2%) were widowers. Also, only 18(21.2%) had a personal source of income while most 76(89.4%) depend on financial support with the majority 36(42.4%) mainly from family and voluntary donations. It was observed that 75.3% had psychiatric morbidity among which 48.2% had Dementia, 16.5% had Schizophrenia and only 10.6% were diagnosed with Depression. \u0000Conclusion: This study lends credence to the fact that aging brings with it certain health challenges that may affect their well-being, especially in developing countries where socioeconomic ado poses significant setbacks in the care of the elderly. In view of the challenges identified among the residents of the old people’s home in Yaba; it is pertinent that efforts must be geared towards the establishment of qualitative medical facilities, especially for those with recognized physical or mental health challenges and poor socioeconomic status to cushion the effect of Mental illness.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42261688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Kluver Bucy Syndrome: An Overview of the Clinical Interplay Kluver - Bucy综合征:临床相互作用综述
Pub Date : 2022-12-20 DOI: 10.9734/indj/2022/v18i3350
Adedeji Okikiade, Aromedonghene Osharode, Natalie Aremu, K. U. Chibuike, Damisola Ogunesan, Olojede Olubunmi
Kluver Bucy Syndrome (KBS) was initially reported by Sanger Brown and Edward Albert Sharpey-Schafer. In 1939, a bilateral temporal lobectomy was conducted on a Rhesus monkey named Aurora. Three weeks after this procedure, Aurora began to exhibit behavioral changes. These behavioral changes exhibited by Aurora were observed and recorded by Paul Clancy Bucy, a neurosurgeon, and Heinrich Kluver, a neuropsychiatrist; these behavioral changes were given the name Kluver-Bucy syndrome. The first human Kluver-Bucy case was diagnosed in 1955 in a 22-year-old male patient. Kluver-Bucy syndrome (KBS) is a complex neuropsychiatric disease that usually occurs after bilateral damage to the medial temporal lobes. The syndrome is mainly seen in adults, male and female equally. However, although the syndrome can also be seen in children, the symptoms in children are slightly different from how the symptoms manifest in adults. There are a plethora of etiologies and manifestations of KBS, but it most commonly manifests as a triad of hypersexuality, hyperorality, and hyperphagia. The diagnosis of KBS is primarily centered around the identification of damages to the medial lobe of the brain using signs and symptoms, imaging studies, and most importantly, Magnetic Resonant Imaging (MRI). It is also essential to rule out and confirm possible differentials and etiologies during the management of KBS. KBS has no known cure, but the various manifestations can be ameliorated with medications like antidepressants and antipsychotics. The prognosis is generally poor for KBS.
Kluver - Bucy综合征(KBS)最早由Sanger Brown和Edward Albert Sharpey-Schafer报道。1939年,对一只名叫奥罗拉的恒河猴进行了双侧颞叶切除术。手术后三周,奥罗拉开始表现出行为上的变化。神经外科医生保罗·克兰西·布西和神经精神病学家海因里希·克鲁弗观察并记录了奥罗拉表现出的这些行为变化;这些行为变化被命名为Kluver-Bucy综合征。第一例人类Kluver-Bucy病例于1955年在一名22岁的男性患者中被诊断出来。Kluver-Bucy综合征(KBS)是一种复杂的神经精神疾病,通常发生在双侧内侧颞叶损伤后。该综合征主要见于成年人,男女平等。然而,虽然该综合征也可以在儿童中看到,但儿童的症状与成人的症状表现略有不同。KBS的病因和表现多种多样,但最常见的表现是性欲亢进、性欲亢进和贪食症。KBS的诊断主要是通过体征和症状,影像学检查,最重要的是磁共振成像(MRI)来识别大脑内侧叶的损伤。在KBS的管理过程中,排除和确认可能的鉴别和病因也很重要。KBS没有已知的治疗方法,但可以通过抗抑郁药和抗精神病药等药物改善各种症状。KBS的预后通常很差。
{"title":"Kluver Bucy Syndrome: An Overview of the Clinical Interplay","authors":"Adedeji Okikiade, Aromedonghene Osharode, Natalie Aremu, K. U. Chibuike, Damisola Ogunesan, Olojede Olubunmi","doi":"10.9734/indj/2022/v18i3350","DOIUrl":"https://doi.org/10.9734/indj/2022/v18i3350","url":null,"abstract":"Kluver Bucy Syndrome (KBS) was initially reported by Sanger Brown and Edward Albert Sharpey-Schafer. In 1939, a bilateral temporal lobectomy was conducted on a Rhesus monkey named Aurora. Three weeks after this procedure, Aurora began to exhibit behavioral changes. These behavioral changes exhibited by Aurora were observed and recorded by Paul Clancy Bucy, a neurosurgeon, and Heinrich Kluver, a neuropsychiatrist; these behavioral changes were given the name Kluver-Bucy syndrome. The first human Kluver-Bucy case was diagnosed in 1955 in a 22-year-old male patient. \u0000Kluver-Bucy syndrome (KBS) is a complex neuropsychiatric disease that usually occurs after bilateral damage to the medial temporal lobes. The syndrome is mainly seen in adults, male and female equally. However, although the syndrome can also be seen in children, the symptoms in children are slightly different from how the symptoms manifest in adults. There are a plethora of etiologies and manifestations of KBS, but it most commonly manifests as a triad of hypersexuality, hyperorality, and hyperphagia. \u0000The diagnosis of KBS is primarily centered around the identification of damages to the medial lobe of the brain using signs and symptoms, imaging studies, and most importantly, Magnetic Resonant Imaging (MRI). It is also essential to rule out and confirm possible differentials and etiologies during the management of KBS. KBS has no known cure, but the various manifestations can be ameliorated with medications like antidepressants and antipsychotics. The prognosis is generally poor for KBS.","PeriodicalId":90556,"journal":{"name":"International neuropsychiatric disease journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46807297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
International neuropsychiatric disease journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1