Pub Date : 2020-12-31DOI: 10.35248/2329-8847.20.S3.005
Yuxiang Sun
Sarcopenia is a debilitating muscle-wasting disease that is the major cause of frailty and disability in aging. Ghrelin (aka acylated ghrelin, AG) is a circulating peptide hormone with an unique octanoylation on Ser3. AG induces growth hormone (GH) secretion, increases food intake, and promotes adiposity and insulin resistance via its receptor, Growth Hormone Secretagogue Receptor (GHS-R). Unlike AG, unacylated ghrelin (UAG) is a peptide generated from the same ghrelin gene with amino acid sequence identical to AG but without the octanoylation modification, so UAG does not activate GHS-R. Intriguingly, both AG and UAG have been shown to promote differentiation and fusion of muscle C2C12 cells, regulate metabolic and mitochondrial signaling pathways in myotubes, and attenuate fasting- or denervation-induced muscle atrophy. Furthermore, it has also been shown that ghrelin gene deficiency increases vulnerability to fasting-induced muscle loss in aging mice, and AG and UAG effectively protects against muscle atrophy of aging mice. Because UAG doesn’t bind to GHS-R, it doesn’t have the undesired side-effects of elevated GH-release and increased obesity as AG. In summary, UAG has an impressive anti-atrophic effect in muscle protecting against muscle atrophy in aging, it has potential to be a unique and superior therapeutic candidate for muscle-wasting diseases such as sarcopenia.
{"title":"Thrifty Hormone Ghrelin: The Secret of Aging Muscularly","authors":"Yuxiang Sun","doi":"10.35248/2329-8847.20.S3.005","DOIUrl":"https://doi.org/10.35248/2329-8847.20.S3.005","url":null,"abstract":"Sarcopenia is a debilitating muscle-wasting disease that is the major cause of frailty and disability in aging. Ghrelin (aka acylated ghrelin, AG) is a circulating peptide hormone with an unique octanoylation on Ser3. AG induces growth hormone (GH) secretion, increases food intake, and promotes adiposity and insulin resistance via its receptor, Growth Hormone Secretagogue Receptor (GHS-R). Unlike AG, unacylated ghrelin (UAG) is a peptide generated from the same ghrelin gene with amino acid sequence identical to AG but without the octanoylation modification, so UAG does not activate GHS-R. Intriguingly, both AG and UAG have been shown to promote differentiation and fusion of muscle C2C12 cells, regulate metabolic and mitochondrial signaling pathways in myotubes, and attenuate fasting- or denervation-induced muscle atrophy. Furthermore, it has also been shown that ghrelin gene deficiency increases vulnerability to fasting-induced muscle loss in aging mice, and AG and UAG effectively protects against muscle atrophy of aging mice. Because UAG doesn’t bind to GHS-R, it doesn’t have the undesired side-effects of elevated GH-release and increased obesity as AG. In summary, UAG has an impressive anti-atrophic effect in muscle protecting against muscle atrophy in aging, it has potential to be a unique and superior therapeutic candidate for muscle-wasting diseases such as sarcopenia.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46509224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-04-06DOI: 10.35248/2329-8847.20.08.222
C. Gettel, E. Goldberg
In many emergency departments (EDs) around the world, providers care for patients who have experienced injuries related to a fall. Approximately 30% of older adults fall each year [1], resulting in serious injuries, decreased mobility, and loss of independence [2]. The annual Medicare costs for older adult falls is estimated at $31.3 billion and only expected to increase as the population continues to age [3].
{"title":"Fall Prevention Intervention in the Emergency Department for Older Adults","authors":"C. Gettel, E. Goldberg","doi":"10.35248/2329-8847.20.08.222","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.222","url":null,"abstract":"In many emergency departments (EDs) around the world, providers care for patients who have experienced injuries related to a fall. Approximately 30% of older adults fall each year [1], resulting in serious injuries, decreased mobility, and loss of independence [2]. The annual Medicare costs for older adult falls is estimated at $31.3 billion and only expected to increase as the population continues to age [3].","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43522023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.224
C. Mullen
This summary paper focuses upon personal locus of control (LOC) orientation and control beliefs in relation with the science of aging, environment, and decision-making in the context of the shibboleth construct. An original dissertation and peer-reviewed paper derivative of the dissertation explored advancement intention in Canadian power engineering. LOC operated as an independent variable (IV) in both the dissertation and the peer-reviewed paper. This summary serves to encourage future research in the area of LOC orientation related to selected aspects of aging, experience, and decision-making.
{"title":"Aging Science: Locus of Control and the Shibboleth Lens","authors":"C. Mullen","doi":"10.35248/2329-8847.20.08.224","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.224","url":null,"abstract":"This summary paper focuses upon personal locus of control (LOC) orientation and control beliefs in relation with the science of aging, environment, and decision-making in the context of the shibboleth construct. An original dissertation and peer-reviewed paper derivative of the dissertation explored advancement intention in Canadian power engineering. LOC operated as an independent variable (IV) in both the dissertation and the peer-reviewed paper. This summary serves to encourage future research in the area of LOC orientation related to selected aspects of aging, experience, and decision-making.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70002861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.239
H. Shintaku
Human brain tissue has a limited ability to regenerate. Cerebral palsy (CP) is a disorder that results from brain injury, most notably hypoxic ischemic encephalopathy (HIE), during the neonatal period. Once the brain-damaging process has progressed to exhibit CP pathology, there is no effective treatment. Therefore, halting this progressive process is important for preventing or minimizing the severity of CP. Therapeutic hypothermia (TH) is an established method widely practiced for this purpose, and TH alone can decrease the mortality rate without increasing the risk of severe disability among survivors [1]. One recent registry study, however, suggests that nearly half of TH can result in some unwanted aftereffects [2]. Stem cell therapy is a newer approach with the potential to repair damaged cells in CP lesions. In 2014, researchers in the United States reported the effectiveness of a combination of TH and autologous cord blood therapy in improving the neurodevelopmental outcome of HIE [3]. By the end of 2014, the Japan Agency for Medical Research and Development funded a clinical trial of autologous cord blood therapy for HIE.
{"title":"Current Status and Future of Autologous Cord Blood Stem Cell Therapy for Cerebral Palsy","authors":"H. Shintaku","doi":"10.35248/2329-8847.20.08.239","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.239","url":null,"abstract":"Human brain tissue has a limited ability to regenerate. Cerebral palsy (CP) is a disorder that results from brain injury, most notably hypoxic ischemic encephalopathy (HIE), during the neonatal period. Once the brain-damaging process has progressed to exhibit CP pathology, there is no effective treatment. Therefore, halting this progressive process is important for preventing or minimizing the severity of CP. Therapeutic hypothermia (TH) is an established method widely practiced for this purpose, and TH alone can decrease the mortality rate without increasing the risk of severe disability among survivors [1]. One recent registry study, however, suggests that nearly half of TH can result in some unwanted aftereffects [2]. Stem cell therapy is a newer approach with the potential to repair damaged cells in CP lesions. In 2014, researchers in the United States reported the effectiveness of a combination of TH and autologous cord blood therapy in improving the neurodevelopmental outcome of HIE [3]. By the end of 2014, the Japan Agency for Medical Research and Development funded a clinical trial of autologous cord blood therapy for HIE.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70003458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.241
H. Shiratsuchi, Reiko Sekino, Takaaki Tamagawa, T. Kaneko
Xerostomia often occurs in elderly patients due to Sjogren’s syndrome, sialadenitis, IgG4-related disease, diabetes, dyslipidemia, and side-effects from certain medications. It is defined as a disturbance in saliva secretion, which can be triggered by radiation therapy and causes many oral and dental problems. Therefore, it is necessary to ameliorate oral symptoms and regenerate salivary glands in patients with these diseases. To relieve xerostomia and stomatitis, herbal medicines such as Japanese traditional medicine (Kampo) are often applied. Kampo therapy is effective for dry mouth symptoms. However, the salivary gland is complex and it is difficult to regenerate the salivary gland through clinical treatment. Byakkokaninjinto and Goreisan are often used as Kampo therapy for xerostomia through regulation of aquaporins. To investigate salivary gland regeneration after inflammation and atrophy, ductligation animal models were used in our previous studies. This model revealed that cytoskeletal changes and the distributions of small Rho GTPases, fibroblast growth factors, and β-catenin have important roles in cell proliferation and differentiation during submandibular gland regeneration.
{"title":"Herbal Medicine Treatment for Xerostomia in Elderly Patients and Salivary Gland Regeneration Research","authors":"H. Shiratsuchi, Reiko Sekino, Takaaki Tamagawa, T. Kaneko","doi":"10.35248/2329-8847.20.08.241","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.241","url":null,"abstract":"Xerostomia often occurs in elderly patients due to Sjogren’s syndrome, sialadenitis, IgG4-related disease, diabetes, dyslipidemia, and side-effects from certain medications. It is defined as a disturbance in saliva secretion, which can be triggered by radiation therapy and causes many oral and dental problems. Therefore, it is necessary to ameliorate oral symptoms and regenerate salivary glands in patients with these diseases. To relieve xerostomia and stomatitis, herbal medicines such as Japanese traditional medicine (Kampo) are often applied. Kampo therapy is effective for dry mouth symptoms. However, the salivary gland is complex and it is difficult to regenerate the salivary gland through clinical treatment. Byakkokaninjinto and Goreisan are often used as Kampo therapy for xerostomia through regulation of aquaporins. To investigate salivary gland regeneration after inflammation and atrophy, ductligation animal models were used in our previous studies. This model revealed that cytoskeletal changes and the distributions of small Rho GTPases, fibroblast growth factors, and β-catenin have important roles in cell proliferation and differentiation during submandibular gland regeneration.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70003466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.232
I. Sindhuja
Today the current share of youth denoted by the pyramid share of sets means the rate is double the undeveloped area compared to developed area. The share of elderly individuals will continue to be most pronounced among more developed countries in the coming decades. By mid 60 th century will represent nearly one-third of the population of wealthy nations while the corresponding figure for the poorest countries underscores.
{"title":"Growth of Elders and their Population Comparison Globally","authors":"I. Sindhuja","doi":"10.35248/2329-8847.20.08.232","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.232","url":null,"abstract":"Today the current share of youth denoted by the pyramid share of sets means the rate is double the undeveloped area compared to developed area. The share of elderly individuals will continue to be most pronounced among more developed countries in the coming decades. By mid 60 th century will represent nearly one-third of the population of wealthy nations while the corresponding figure for the poorest countries underscores.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-1"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70003557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.8.243
Kristin R. Newman
In November 2019, a paper I was lead author on, “The role of internet-based digital tools in reducing social isolation and addressing support needs among informal caregivers: a scoping review,” was published in BMC Public Health [1]. Little did we know that the issue of social isolation would soon become crucially important for vastly more people worldwide due to the COVID-19 pandemic. Before the pandemic we could see that without proper support informal caregivers were vulnerable to social isolation. Loneliness and caregiving pressures have substantially increased during the COVID-19 era for unpaid informal caregivers who care for a sibling, child, spouse, friend, or neighbor. Many informal caregivers do not have a choice in taking on this role – it often just falls to them because no one else is willing or able to do it. Often, acquaintances of these informal caregivers do not know that the individual has taken on this role. For example, there is little acknowledgment that young people (under 18 years of age) sometimes take on the responsibility of caring for a loved one such as a grandparent, parent, or sibling. Many professionals do not even address youth when discussing the care of a loved one – it is often assumed that an adult provides the care [2]. These underappreciated caregivers need to be acknowledged and supported.
{"title":"Relevance of Digitalization for Informal Caregivers to Address Support Needs and Reducing Social Isolation during the COVID-19 Pandemic","authors":"Kristin R. Newman","doi":"10.35248/2329-8847.20.8.243","DOIUrl":"https://doi.org/10.35248/2329-8847.20.8.243","url":null,"abstract":"In November 2019, a paper I was lead author on, “The role of internet-based digital tools in reducing social isolation and addressing support needs among informal caregivers: a scoping review,” was published in BMC Public Health [1]. Little did we know that the issue of social isolation would soon become crucially important for vastly more people worldwide due to the COVID-19 pandemic. Before the pandemic we could see that without proper support informal caregivers were vulnerable to social isolation. Loneliness and caregiving pressures have substantially increased during the COVID-19 era for unpaid informal caregivers who care for a sibling, child, spouse, friend, or neighbor. Many informal caregivers do not have a choice in taking on this role – it often just falls to them because no one else is willing or able to do it. Often, acquaintances of these informal caregivers do not know that the individual has taken on this role. For example, there is little acknowledgment that young people (under 18 years of age) sometimes take on the responsibility of caring for a loved one such as a grandparent, parent, or sibling. Many professionals do not even address youth when discussing the care of a loved one – it is often assumed that an adult provides the care [2]. These underappreciated caregivers need to be acknowledged and supported.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70003977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fall Prevention Intervention in the Emergency Department for Older Adults.","authors":"Cameron J Gettel, Elizabeth M Goldberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7386420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38205543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.220
Ariadna Gonzalez
Introduction: A review of cases in the literature on auditory hallucinations, and associated clinical characteristics, to late onset psychosis and hearing loss is performed. It has been speculated that Mozart was suffering from musical auditory hallucinations and that he used these hallucinating phenomena to write his works. Musical hallucinations that appear in elderly women may have different causes and there are few cases described in the literature have been described in different clinical situations: loss of hearing ability; brain lesions, vascular processes and encephalitis; consumption of psychoactive substances and psychiatric disorders. Methods: Cases published in the literature on auditory hallucinations from 2011 to 2019 are reviewed. Results: Different cases are described, from episodes of musical auditory hallucinations to: late age, after a surgical process, after using a medication, due to hearing problems, by musicians, by evocations of remote memory and during dreams, in addition to perception of music in patients with previous mental health disorders. Conclusion: Musical hallucinations are a rare and complex phenomenon. Clinically they may be more frequent in women and in old age. Musical hallucinations are a borderline pathology between neurology, otolaryngology and little-known psychiatry, which is often mistakenly linked to a mental illness.
{"title":"A Review of Cases in the Literature on Auditory Hallucinations: It would be Possible for Mozart to Hallucinate his Music","authors":"Ariadna Gonzalez","doi":"10.35248/2329-8847.20.08.220","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.220","url":null,"abstract":"Introduction: A review of cases in the literature on auditory hallucinations, and associated clinical characteristics, to late onset psychosis and hearing loss is performed. It has been speculated that Mozart was suffering from musical auditory hallucinations and that he used these hallucinating phenomena to write his works. Musical hallucinations that appear in elderly women may have different causes and there are few cases described in the literature have been described in different clinical situations: loss of hearing ability; brain lesions, vascular processes and encephalitis; consumption of psychoactive substances and psychiatric disorders. Methods: Cases published in the literature on auditory hallucinations from 2011 to 2019 are reviewed. Results: Different cases are described, from episodes of musical auditory hallucinations to: late age, after a surgical process, after using a medication, due to hearing problems, by musicians, by evocations of remote memory and during dreams, in addition to perception of music in patients with previous mental health disorders. Conclusion: Musical hallucinations are a rare and complex phenomenon. Clinically they may be more frequent in women and in old age. Musical hallucinations are a borderline pathology between neurology, otolaryngology and little-known psychiatry, which is often mistakenly linked to a mental illness.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70002770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.35248/2329-8847.20.08.236
Mehdi Kushkestani, M. Moghadassi, Mohsen Parvani, S. Nosrani, Sohrab Rezaei
Background and purpose: Aging is associated with a significant reduction in biological, physiological and functional capacity. The aim of the present research was to investigate the relationship between physical activity level and physical performance indicators in the community-dwelling elderly people. Methods: In this cross-sectional study, 431 community-dwelling older adults (>60) voluntarily were recruited from the Tehran (Iran). General and demographic features, physical activity levels, and physical performance factors were measured and recorded by demographic, PASE questionnaires, and physical function tests. Results: Age was significantly correlated with mobility, balance, speed, and lower body power (p<0.00). Also, there was a significantly positive correlation between balance (r=0.219, p<0.01), mobility(r=0.140, p<0.01) speed test (r=0.220, p<0.00) and the lower body power (r=0.237, p<0.01) with physical activity levels. Also, as expected different physical function factors were significantly difference between insufficient and sufficient physical activity group (p<0.01). Conclusion: The use of strategies such as regular exercise training at parks and public places with a focus on exercise physiology experts, in addition to preventing a decline in performance, can lead to the prevention of many agingrelated disorders and increase public health.
{"title":"Physical Activity as a Preventive Factor to Aging-Related Physical Dysfunction in Iranian Community-Dwelling Elderly","authors":"Mehdi Kushkestani, M. Moghadassi, Mohsen Parvani, S. Nosrani, Sohrab Rezaei","doi":"10.35248/2329-8847.20.08.236","DOIUrl":"https://doi.org/10.35248/2329-8847.20.08.236","url":null,"abstract":"Background and purpose: Aging is associated with a significant reduction in biological, physiological and functional capacity. The aim of the present research was to investigate the relationship between physical activity level and physical performance indicators in the community-dwelling elderly people. Methods: In this cross-sectional study, 431 community-dwelling older adults (>60) voluntarily were recruited from the Tehran (Iran). General and demographic features, physical activity levels, and physical performance factors were measured and recorded by demographic, PASE questionnaires, and physical function tests. Results: Age was significantly correlated with mobility, balance, speed, and lower body power (p<0.00). Also, there was a significantly positive correlation between balance (r=0.219, p<0.01), mobility(r=0.140, p<0.01) speed test (r=0.220, p<0.00) and the lower body power (r=0.237, p<0.01) with physical activity levels. Also, as expected different physical function factors were significantly difference between insufficient and sufficient physical activity group (p<0.01). Conclusion: The use of strategies such as regular exercise training at parks and public places with a focus on exercise physiology experts, in addition to preventing a decline in performance, can lead to the prevention of many agingrelated disorders and increase public health.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"8 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70003275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}