Pub Date : 2018-01-01DOI: 10.4172/2329-8847.1000188
A. Mcintosh
In this piece, I explore the onset of geriatric medicine and the excitement surrounding the up and coming field in medicine, and contrast the past with the current attitudes of students towards pursuing a career in geriatrics. The trailblazers of geriatric medicine demonstrated an unrelenting passion for their work which is why the field gained traction in the 1900s. These physicians worked to change the negative perception of how older people were viewed in medicine. It was once thought that there was nothing to be done for those experiencing end stages of disease or dealing with the aging process. Due to the efforts trailblazers like Marjory Warren, care for the chronically ill and older people became a fixture in all parts of medicine; however, the idea of working with the geriatric population is not fostering an interest in the current generation of students as it did in the past. Medical students are not gravitating to field of geriatric medicine due to a lack of financial reward, prestige, and ageism. Is it possible to change their perceptions, and if so, what changes in geriatrics need to be made to do so?
{"title":"Geriatric Medicine: A Student's Thoughts","authors":"A. Mcintosh","doi":"10.4172/2329-8847.1000188","DOIUrl":"https://doi.org/10.4172/2329-8847.1000188","url":null,"abstract":"In this piece, I explore the onset of geriatric medicine and the excitement surrounding the up and coming field in medicine, and contrast the past with the current attitudes of students towards pursuing a career in geriatrics. The trailblazers of geriatric medicine demonstrated an unrelenting passion for their work which is why the field gained traction in the 1900s. These physicians worked to change the negative perception of how older people were viewed in medicine. It was once thought that there was nothing to be done for those experiencing end stages of disease or dealing with the aging process. Due to the efforts trailblazers like Marjory Warren, care for the chronically ill and older people became a fixture in all parts of medicine; however, the idea of working with the geriatric population is not fostering an interest in the current generation of students as it did in the past. Medical students are not gravitating to field of geriatric medicine due to a lack of financial reward, prestige, and ageism. Is it possible to change their perceptions, and if so, what changes in geriatrics need to be made to do so?","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"51 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70271404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-8847.1000189
Raúl Antunes, Nuno Couto, D. Monteiro, J. Moutão, D. Marinho, L. Cid
Goal content, represented by intrinsic and extrinsic goals, regulates motivation. The present study was undertaken to analyze the impact of goal content leading to physical activity in older adults (60 to 90 years), on the subjective well-being variables and to evaluate the differences between such variables according to the physical activity level practiced. Structural equation models (SEM) constituted by the principles of both regression and factorial analysis was used for analyzing the data obtained from The Goal Content for Exercise Questionnaire (GCEQ), The Positive and Negative Affect Schedule (PANAS) and The International Physical Activity Questionnaire (IPAQ-short form). A substantial positive effect of extrinsic goal content on satisfaction with life (β.24) and negative affect (β.27) and a substantial positive effect of intrinsic objectives on positive affect (β.35) were observed. Health (6.03 ± 0.74) was the most important motive whereas social recognition (3.77 ± 1.36) was the least important one. Individuals with higher physical activity had greater positive effect and satisfaction with life and lower levels of negative affect. This study is of significance in comprehending the role of physical activity and well-being among older adults.
{"title":"Goal Content for the Practice of Physical Activity","authors":"Raúl Antunes, Nuno Couto, D. Monteiro, J. Moutão, D. Marinho, L. Cid","doi":"10.4172/2329-8847.1000189","DOIUrl":"https://doi.org/10.4172/2329-8847.1000189","url":null,"abstract":"Goal content, represented by intrinsic and extrinsic goals, regulates motivation. The present study was undertaken to analyze the impact of goal content leading to physical activity in older adults (60 to 90 years), on the subjective well-being variables and to evaluate the differences between such variables according to the physical activity level practiced. Structural equation models (SEM) constituted by the principles of both regression and factorial analysis was used for analyzing the data obtained from The Goal Content for Exercise Questionnaire (GCEQ), The Positive and Negative Affect Schedule (PANAS) and The International Physical Activity Questionnaire (IPAQ-short form). A substantial positive effect of extrinsic goal content on satisfaction with life (β.24) and negative affect (β.27) and a substantial positive effect of intrinsic objectives on positive affect (β.35) were observed. Health (6.03 ± 0.74) was the most important motive whereas social recognition (3.77 ± 1.36) was the least important one. Individuals with higher physical activity had greater positive effect and satisfaction with life and lower levels of negative affect. This study is of significance in comprehending the role of physical activity and well-being among older adults.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"6 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70271468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-8847.1000191
Masayuki Watanabe
Background: Equilibrium is a primary factor that describes and predicts elderly people’s falling and fear of falling. However, elucidation of the relationship between equilibrium and cognitive function and the influence of cognition function on equilibrium in elderly people is required. Methods: This study sought to illustrate the characteristics of the equilibrium function in elderly people, focusing on the vividness and controllability of the body schema as a cognitive function and analyzing its relationship with body sway (in the one-leg standing test with eyes open) from a lifelong development perspective. Movement distance and the outer area in body sway in the one-leg standing test with eyes open were measured for 139 participants including children, college students, and elderly people. In addition, the vividness and controllability of the body schema were measured using reaction times in a video game-style imaginary body movement test. Results: In the college students, both types of cognitive function were significantly correlated with equilibrium, indicating an association between these two variables. Moreover, different relationships between equilibrium and cognitive function were observed in children and elderly people. Therefore, equilibrium in the elderly people did not deteriorate to the extent that it reflected the characteristics of young children; rather, it was influenced by multiple factors that attributed to the deterioration of the motor organ while maintaining basic strategies continued from early adulthood. Conclusion: Specific outcomes could be achieved to maintain the health of elderly people via future examining of the relationship between equilibrium and cognitive function.
{"title":"Does the Controllability of the Body Schema Predict Equilibrium in Elderly People? Characteristics of Relationships from a Lifelong Development Perspective","authors":"Masayuki Watanabe","doi":"10.4172/2329-8847.1000191","DOIUrl":"https://doi.org/10.4172/2329-8847.1000191","url":null,"abstract":"Background: Equilibrium is a primary factor that describes and predicts elderly people’s falling and fear of falling. However, elucidation of the relationship between equilibrium and cognitive function and the influence of cognition function on equilibrium in elderly people is required. Methods: This study sought to illustrate the characteristics of the equilibrium function in elderly people, focusing on the vividness and controllability of the body schema as a cognitive function and analyzing its relationship with body sway (in the one-leg standing test with eyes open) from a lifelong development perspective. Movement distance and the outer area in body sway in the one-leg standing test with eyes open were measured for 139 participants including children, college students, and elderly people. In addition, the vividness and controllability of the body schema were measured using reaction times in a video game-style imaginary body movement test. Results: In the college students, both types of cognitive function were significantly correlated with equilibrium, indicating an association between these two variables. Moreover, different relationships between equilibrium and cognitive function were observed in children and elderly people. Therefore, equilibrium in the elderly people did not deteriorate to the extent that it reflected the characteristics of young children; rather, it was influenced by multiple factors that attributed to the deterioration of the motor organ while maintaining basic strategies continued from early adulthood. Conclusion: Specific outcomes could be achieved to maintain the health of elderly people via future examining of the relationship between equilibrium and cognitive function.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"1 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70271541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-8847.1000194
M. Raphanel, Gabrielle Shaughness, W. Seiple, A. Arleo
Purpose: This study surveys current low vision rehabilitation practice methodologies among French practitioners and it describes their opinions about the utility of using virtual reality as a tool for low vision rehabilitation training in patients with age-related macular degeneration. Methods: An online questionnaire was distributed between October 2017 and February 2018. 471 orthoptists (110 students and 361 graduates) responded to the survey. Questions concerned the orthoptist’s educational and demographic background, extent of training in virtual reality as a reeducation tool, and mode of practice including frequency of patient visits, goals, and methods of rehabilitation training. Results: Out of 361 practicing orthoptists, 47.75% were low vision rehabilitation providers, and 52.25% were not. A provider’s likelihood of using low vision rehabilitation immediately after graduating from university was positively correlated to his confidence in the training he had received. Most respondents were receptive to using virtual reality as a reeducation tool. Conclusions: Analysis of current low vision rehabilitation practice demonstrates no standardization of treatment protocols among providers. Although orthoptists overall acknowledge the benefits of virtual reality as a rehabilitation tool, orthoptist curriculum varies greatly across universities, which thus affects a provider’s likelihood of offering low vision rehabilitation. Moreover, this lack of standardization is a problem worldwide, which suggests a need for better clinical guidelines in low vision rehabilitation practice.
{"title":"Current Practice in Low Vision Rehabilitation of Age-related Macular Degeneration and Usefulness of Virtual Reality as a Rehabilitation Tool","authors":"M. Raphanel, Gabrielle Shaughness, W. Seiple, A. Arleo","doi":"10.4172/2329-8847.1000194","DOIUrl":"https://doi.org/10.4172/2329-8847.1000194","url":null,"abstract":"Purpose: This study surveys current low vision rehabilitation practice methodologies among French practitioners and it describes their opinions about the utility of using virtual reality as a tool for low vision rehabilitation training in patients with age-related macular degeneration. Methods: An online questionnaire was distributed between October 2017 and February 2018. 471 orthoptists (110 students and 361 graduates) responded to the survey. Questions concerned the orthoptist’s educational and demographic background, extent of training in virtual reality as a reeducation tool, and mode of practice including frequency of patient visits, goals, and methods of rehabilitation training. Results: Out of 361 practicing orthoptists, 47.75% were low vision rehabilitation providers, and 52.25% were not. A provider’s likelihood of using low vision rehabilitation immediately after graduating from university was positively correlated to his confidence in the training he had received. Most respondents were receptive to using virtual reality as a reeducation tool. Conclusions: Analysis of current low vision rehabilitation practice demonstrates no standardization of treatment protocols among providers. Although orthoptists overall acknowledge the benefits of virtual reality as a rehabilitation tool, orthoptist curriculum varies greatly across universities, which thus affects a provider’s likelihood of offering low vision rehabilitation. Moreover, this lack of standardization is a problem worldwide, which suggests a need for better clinical guidelines in low vision rehabilitation practice.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"1 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-8847.1000194","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70271747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-01-01DOI: 10.4172/2329-8847.1000198
Fereshteh Barei
Social and health policies have an important role and responsibility in defining these new types of “aging”. They can provide a “value added” environment for healthy and active aging. Living longer, but also healthier and actively can save a lot on health care expenditures and can even generate profits for the society through trans generational collaborations, sharing the wisdom and experience of the elderly with younger generations to solve everyday problems.
{"title":"Designing New Ways of Aging: Towards Age Friendly Policies and Societies","authors":"Fereshteh Barei","doi":"10.4172/2329-8847.1000198","DOIUrl":"https://doi.org/10.4172/2329-8847.1000198","url":null,"abstract":"Social and health policies have an important role and responsibility in defining these new types of “aging”. They can provide a “value added” environment for healthy and active aging. Living longer, but also healthier and actively can save a lot on health care expenditures and can even generate profits for the society through trans generational collaborations, sharing the wisdom and experience of the elderly with younger generations to solve everyday problems.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"7 1","pages":"0-0"},"PeriodicalIF":0.0,"publicationDate":"2018-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70271849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-10-30DOI: 10.4172/2329-8847.1000184
Nguyen dinh Tao, Q. Lam, H. V. Luong
The general infertility rate is around 10% in Vietnam whereas male infertility counts for half of it. 10% of infertile men are diagnosed with the absence of sperm in the semen (azoospermia). Sertoli cells play a major role in the development of healthy sperms. Researchers have known for many years that the Sertoli cell, the supporting element in the testis, regulates germ cell renewal and differentiation. Hence, research on structural changes, especially on the ultrastructure of Sertoli cells of azoospermic patients is essential for an improved diagnosis and treatment of infertile couples. Comparing sertoli cells extracted from patients without epididymal spermatozoa (group I) with cells of patients with epididymal spermatozoa (group II) showed that the cells ultrastructure of the first group differentiates essentially from the second. Sertoli cells extracted from group II patients have a typically shaped nucleus and are close to the sertoli cells of healthy patients in their general morphology. However, the Sertoli cells extracted from patients without epididymal spermatozoa have significantly smaller nuclei and an immature cytoplasm.
{"title":"The Ultrastructure of Sertoli Cells of Azoospermic Men","authors":"Nguyen dinh Tao, Q. Lam, H. V. Luong","doi":"10.4172/2329-8847.1000184","DOIUrl":"https://doi.org/10.4172/2329-8847.1000184","url":null,"abstract":"The general infertility rate is around 10% in Vietnam whereas male infertility counts for half of it. 10% of infertile men are diagnosed with the absence of sperm in the semen (azoospermia). Sertoli cells play a major role in the development of healthy sperms. Researchers have known for many years that the Sertoli cell, the supporting element in the testis, regulates germ cell renewal and differentiation. Hence, research on structural changes, especially on the ultrastructure of Sertoli cells of azoospermic patients is essential for an improved diagnosis and treatment of infertile couples. Comparing sertoli cells extracted from patients without epididymal spermatozoa (group I) with cells of patients with epididymal spermatozoa (group II) showed that the cells ultrastructure of the first group differentiates essentially from the second. Sertoli cells extracted from group II patients have a typically shaped nucleus and are close to the sertoli cells of healthy patients in their general morphology. However, the Sertoli cells extracted from patients without epididymal spermatozoa have significantly smaller nuclei and an immature cytoplasm.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"2017 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44416878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-09-01DOI: 10.4172/2329-8847.1000183
Adarsh Chauhan, Ishita Chauhan
At the start shrinking of body is explained by citing article of Louise Atkinson in which she says your body is one incredibly shrinking one from your brain to your heart –almost everything gets smaller with age. Present article also argues around the concept of shrinkage and its correlation to locally acquired wisdom. Pain in back and neck is described in relation to shrinking of muscles. Brain shrinkage and bony shrinkage is discussed along with measures to prevent it. Heart shrinkage (John Hopkins study) is linked to chest wall shrinkage (community acquired knowledge) through anatomical continuity between heart and thoracic wall. Results of study conducted to assess various aging parameters reveals that chest wall including its attached muscles shrinks towards the core of body i.e. heart and finally article discusses the clinical implications of the ageing phenomenon in backache, sympathetic activation, cardiovascular aging and dietary habits. Cardiovascular aging is described in detail in reference to recent Cedars Sinai hospital study of cardio-sphere derived stem cells and reversal of aging process.
{"title":"Is Ageing Related to Shrinkage of Heart: A Hypothesis","authors":"Adarsh Chauhan, Ishita Chauhan","doi":"10.4172/2329-8847.1000183","DOIUrl":"https://doi.org/10.4172/2329-8847.1000183","url":null,"abstract":"At the start shrinking of body is explained by citing article of Louise Atkinson in which she says your body is one incredibly shrinking one from your brain to your heart –almost everything gets smaller with age. Present article also argues around the concept of shrinkage and its correlation to locally acquired wisdom. Pain in back and neck is described in relation to shrinking of muscles. Brain shrinkage and bony shrinkage is discussed along with measures to prevent it. Heart shrinkage (John Hopkins study) is linked to chest wall shrinkage (community acquired knowledge) through anatomical continuity between heart and thoracic wall. Results of study conducted to assess various aging parameters reveals that chest wall including its attached muscles shrinks towards the core of body i.e. heart and finally article discusses the clinical implications of the ageing phenomenon in backache, sympathetic activation, cardiovascular aging and dietary habits. Cardiovascular aging is described in detail in reference to recent Cedars Sinai hospital study of cardio-sphere derived stem cells and reversal of aging process.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"5 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-8847.1000183","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46750480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-22DOI: 10.4172/2329-8847.1000182
Dinh Le Mai, N. Huy, N. Thanh, Henning Staar
Background: The number of older people in Vietnam has increased substantially for recent years and leading to more aging health problems. The purpose of this study was to assess risky behaviors and their associated factors among the elderly in rural Vietnam. Design: In a cross-sectional study using quantitative methods, 600 elderly (≥ 60 years old) living in a rural district in Northern Vietnam in 2013 were approached for data collection. Logistic regression was undertaken to identify factors associated with each of the risky behaviors, including using alcohol, smoking, and physical inactivity. Results: The frequency of drinking, smoking and physical inactivity among the rural elderly was quite prevalent, 25.17%, 22.17% and 60%, respectively. The multivariate regression analysis revealed that alcohol use was most strongly predicted by gender (male) and age (60-79 years old). Further, smoking behavior was significantly more prevalent among those who were male, younger age, with low social participation, low social support and high social cohesion. In terms of physical inactivity, being female, married, having a caregiver, with low social participation, low social cohesion and high social support were most likely to predict inadequate exercises among the rural older people. Conclusions: Social efforts are important to create social conditions (social participation, social cohesion and social support) that facilitate healthy behaviors among the seniors. The results can be utilized to inform appropriate intervention programs in other similar settings of developing countries.
{"title":"Risky Behaviors and Associated Factors among the Elderly in Rural Vietnam","authors":"Dinh Le Mai, N. Huy, N. Thanh, Henning Staar","doi":"10.4172/2329-8847.1000182","DOIUrl":"https://doi.org/10.4172/2329-8847.1000182","url":null,"abstract":"Background: The number of older people in Vietnam has increased substantially for recent years and leading to more aging health problems. The purpose of this study was to assess risky behaviors and their associated factors among the elderly in rural Vietnam. \u0000Design: In a cross-sectional study using quantitative methods, 600 elderly (≥ 60 years old) living in a rural district in Northern Vietnam in 2013 were approached for data collection. Logistic regression was undertaken to identify factors associated with each of the risky behaviors, including using alcohol, smoking, and physical inactivity. \u0000Results: The frequency of drinking, smoking and physical inactivity among the rural elderly was quite prevalent, 25.17%, 22.17% and 60%, respectively. The multivariate regression analysis revealed that alcohol use was most strongly predicted by gender (male) and age (60-79 years old). Further, smoking behavior was significantly more prevalent among those who were male, younger age, with low social participation, low social support and high social cohesion. In terms of physical inactivity, being female, married, having a caregiver, with low social participation, low social cohesion and high social support were most likely to predict inadequate exercises among the rural older people. \u0000Conclusions: Social efforts are important to create social conditions (social participation, social cohesion and social support) that facilitate healthy behaviors among the seniors. The results can be utilized to inform appropriate intervention programs in other similar settings of developing countries.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"5 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-8847.1000182","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41861724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-07-21DOI: 10.4172/2329-8847.1000181
M. Hafeez, Katherine T. Mun, H. Kamal, K. Szigeti
Introduction: Delusional Misidentification Syndrome (DMS) encompasses a group of disorders in which a person persistently believes the identity of people, places, or objects are altered. Historically, described in psychotic disorders, DMS prevalence is 15.8% in Alzheimer's disease (AD) and 16.6% in dementia with Lewy bodies (DLB). We present a case of DMS in a patient with dementia that incorporates elements of mirrored self-misidentification and phantom boarder syndrome and therapeutic response to a combination of a behavioral intervention and donepezil. Case: 75-year-old white female presented with a four months history of DMS and visual hallucinations. Patient perceived her own reflection in picture glass as an older lady who was trying to steal her "boyfriends." Her "boyfriends" were three pictures of soldiers in her apartment. MMSE was 27/30 (WORLD) and 23/30 (Serial 7s). MRI showed biparietal and right hippocampal atrophy. NPT showed impaired language, spatial abilities, memory, and executive control. She scored <1 percentile on category word fluency, judgement of line orientation, raw complex figures and Beery VMI. Patient was diagnosed with probable AD, using NINCDS-ADRDA and findings on neuropsychological testing (NPT) and MRI. DLB was excluded using McKeith's criteria. After a failed trial of risperidone, she received donepezil and family was instructed to remove photographs. MMSE stable with resolution of the mirrored selfmisidentification at 4 months follow up. Conclusion: Patient's poor response to risperidone is consistent with previous studies suggesting limitations of antipsychotic treatment for psychotic symptoms in AD. Removal of potential symptom trigger along with an acetylcholinesterase inhibitor resulted in remission for up to 4 months. The potentiating effect of donepezil on the cholinergic component of the visuo-amygdaloid pathway/dorsal visual pathway may account for these changes.
{"title":"Delusional Misidentification Syndrome with Response to Donepezil and Behavioral Intervention in a Patient with Dementia","authors":"M. Hafeez, Katherine T. Mun, H. Kamal, K. Szigeti","doi":"10.4172/2329-8847.1000181","DOIUrl":"https://doi.org/10.4172/2329-8847.1000181","url":null,"abstract":"Introduction: Delusional Misidentification Syndrome (DMS) encompasses a group of disorders in which a person persistently believes the identity of people, places, or objects are altered. Historically, described in psychotic disorders, DMS prevalence is 15.8% in Alzheimer's disease (AD) and 16.6% in dementia with Lewy bodies (DLB). We present a case of DMS in a patient with dementia that incorporates elements of mirrored self-misidentification and phantom boarder syndrome and therapeutic response to a combination of a behavioral intervention and donepezil. \u0000 \u0000Case: 75-year-old white female presented with a four months history of DMS and visual hallucinations. Patient perceived her own reflection in picture glass as an older lady who was trying to steal her \"boyfriends.\" Her \"boyfriends\" were three pictures of soldiers in her apartment. MMSE was 27/30 (WORLD) and 23/30 (Serial 7s). MRI showed biparietal and right hippocampal atrophy. NPT showed impaired language, spatial abilities, memory, and executive control. She scored <1 percentile on category word fluency, judgement of line orientation, raw complex figures and Beery VMI. Patient was diagnosed with probable AD, using NINCDS-ADRDA and findings on neuropsychological testing (NPT) and MRI. DLB was excluded using McKeith's criteria. After a failed trial of risperidone, she received donepezil and family was instructed to remove photographs. MMSE stable with resolution of the mirrored selfmisidentification at 4 months follow up. \u0000 \u0000Conclusion: Patient's poor response to risperidone is consistent with previous studies suggesting limitations of antipsychotic treatment for psychotic symptoms in AD. Removal of potential symptom trigger along with an acetylcholinesterase inhibitor resulted in remission for up to 4 months. The potentiating effect of donepezil on the cholinergic component of the visuo-amygdaloid pathway/dorsal visual pathway may account for these changes.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":"5 1","pages":"1-6"},"PeriodicalIF":0.0,"publicationDate":"2017-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-8847.1000181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44987205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-06-26DOI: 10.4172/2329-8847.1000E125
E. Carmeli
This editorial note scrutinizes an important clinical opinion regarding the role of mitochondria in generating differing strength and endurance capabilities in elderly vs. young people. The submaximal effort against resistance, as well as endurance effort differs between young vs. elderly people. This is usually explained by neurophysiological differences, but this editorial note presents a hypothesis regarding the aging mitochondria. Mitochondria in young people obtain all the necessary physical and metabolic properties that are needed and acquired throughout adulthood; yet, mitochondria in elderly people undergo many changes.
{"title":"The Role of Mitochondria in Generating Different Submaximal Strength and Endurance Capabilities in Elderly People","authors":"E. Carmeli","doi":"10.4172/2329-8847.1000E125","DOIUrl":"https://doi.org/10.4172/2329-8847.1000E125","url":null,"abstract":"This editorial note scrutinizes an important clinical opinion regarding the role of mitochondria in generating differing strength and endurance capabilities in elderly vs. young people. The submaximal effort against resistance, as well as endurance effort differs between young vs. elderly people. This is usually explained by neurophysiological differences, but this editorial note presents a hypothesis regarding the aging mitochondria. Mitochondria in young people obtain all the necessary physical and metabolic properties that are needed and acquired throughout adulthood; yet, mitochondria in elderly people undergo many changes.","PeriodicalId":90884,"journal":{"name":"Journal of aging science","volume":" ","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2017-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.4172/2329-8847.1000E125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46116435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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