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Pilot Study on Brain Response to Nursery Rhymes: Comparison between a Musician, a Robot, or a Boombox Player 大脑对童谣反应的初步研究:音乐家、机器人或唱机播放器之间的比较
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.250
Mahsa Soufineyestani, Arshia A. Khan, Rana Imtiaz, Yumna Anwar
Music has been known as a powerful tool that can change brain activities. This pilot study aims to investigate the impact of listening to nursery rhymes on brain Waves specifically Alpha and Beta wave activities when music played by a professional musician, a robot called Pepper, and a boom box. Applying Discrete Wavelet Transform (DWT) and statistical analysis of Electroencephalography (EEG) data revealed a strong correlation between brain wave activities of individuals who listened to music played by a robot or a musician. Also, despite the study hypothesis that listening to nursery rhymes may calm individuals, it made some participants restless.
音乐被认为是一种可以改变大脑活动的强大工具。这项试点研究的目的是调查听儿歌对脑电波的影响,特别是当专业音乐家、一个名叫Pepper的机器人和一个boombox播放音乐时,脑电波的α和β波活动。应用离散小波变换(DWT)和脑电图(EEG)数据的统计分析表明,听机器人或音乐家演奏的音乐的个体脑电波活动之间存在很强的相关性。此外,尽管研究假设听童谣可以让人平静下来,但它却让一些参与者感到不安。
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引用次数: 0
Psychological Status of Elderly 老年人的心理状况
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.256
M. Subramanyam
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引用次数: 0
Psychiatric Impairment in Older Adults 老年人精神障碍
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.E231
M. Subramanyam
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引用次数: 0
Gastrointestinal Tract Microbiome- Derived Pro-inflammatory Neurotoxins in Alzheimerandrsquo;s Disease 阿尔茨海默病胃肠道微生物源性促炎神经毒素
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.S5.002
Yuhai Zhao, V. Jaber, W. Lukiw
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引用次数: 1
Diseases Emerged Till Date 迄今为止出现的疾病
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.S6.E003
M. Subramanyam
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引用次数: 0
Importance of the Parasympathetic Nervous System for Controlling Dry Eye 副交感神经系统对控制干眼的重要性
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.252
K. Tsubota
Tear secretion is very unique to humans but the regulation of tear secretion has remained a mystery for many years. It has been described that the parasympathetic control and the sympathetic control work together to control tear secretion. However, we did not know which of the two is more important. Recently, we have shown that the parasympathetic nervous system in mouse model is more important than the sympathetic nervous system for tearing. In order to prevent dry eye, modern society should emphasize the importance of the parasympathetic nervous system.
人类的泪液分泌是非常独特的,但多年来泪液分泌的调节一直是一个谜。研究表明,副交感神经控制和交感神经控制共同控制泪液分泌。但是,我们不知道两者中哪一个更重要。最近,我们发现在小鼠模型中,副交感神经系统比交感神经系统更重要。为了预防干眼症,现代社会应该强调副交感神经系统的重要性。
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引用次数: 0
Social Sciences and Education vs. Aging: A Sociological Appraisal 社会科学与教育与老龄化:社会学评价
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.9.S4.003
M. Sheykhi
Social sciences as collective sciences including social work,sociology and many more defend and support aging; how peoplecan live to have longer lives. Social work as an independentsocial science deeply approaches people entering aging period tostay healthier and safer. Such an approach endows longer life topeople aged 60-65 and over. Similarly, studying human groups inqualitative and quantitative manners, contribute toupgrading human life expectancy. On the other hand, educationas a master discipline contributes to how people can better adoptmeasures to live more prosperously-leading to longer life. So, thetwo parameters have caused increasing longevity in majority ofthe countries in the world.
社会科学作为集体科学,包括社会工作、社会学和许多其他学科,捍卫和支持老龄化;人们怎样才能活得更久。社会工作作为一门独立的社会科学,深入研究进入老年期的人如何保持健康和安全。这种方法使60-65岁及以上的人寿命更长。同样,对人类群体进行定性和定量的研究,有助于提高人类的预期寿命。另一方面,教育作为一门主学科,有助于人们更好地采取措施,生活得更富裕,从而延长寿命。因此,这两个因素导致了世界上大多数国家的寿命延长。
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引用次数: 0
Granulomatous Mastitis: Is it Boon or Bane?? 肉芽肿性乳腺炎:是福还是祸?
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.S6.002
K. SatishChaitanya, Prateek Sharda, Ananya Deori, Anamika Kumar, M. Verma, A. Syed, B. Ravi
Introduction: Granulomatous mastitis (GM) is a rare benign breast disease subdivided into idiopathic and specific. The clinical and imaging diagnosis is often challenging as it can mimic malignancy. It has characteristic histological features of multinucleated giant cells, non-caseating granulomas, and necrosis. The treatment is still controversial with steroid therapy as a primary modality and surgery are avoided due to fistula formation and recurrences. Aims and objectives: This study aims to establish the descriptive features of granulomatous mastitis and the correlation between various risk factors affecting and leading to the recurrence of the disease. Materials and methods: This was a retrospective study carried out for a period of 12 months at IBCC (Integrated Breast Care Centre) established in AIIMS, Rishikesh, Uttarakhand. Out of 2567 patients who presented to OPD, 34 patients were diagnosed with granulomatous mastitis included in this study. Results: Of all the 34 patients who presented with granulomatous mastitis, the mean age 38.32 yrs, all of them are females (100%) with a mean duration of 2.55 months. Breast lump noted in 82.4%, 85.3% with Pain, 17.6% had Discharge. On examination, the mean largest size is 3.41 ± 1.15 cm, 67.6% had Tenderness. We observed statistical significance (P<0.05) between pathological features, giant cells, AFB positivity, antibiotics, steroid, and antituberculosis treatment with recurrence. Conclusion: Granulomatous mastitis is a special disease scenario that will mimic malignancy but have low rates of transformation but it has more financial burden on patients due to its chronicity resulting in poor quality of life which is a Boon and Bane for these patients.
简介:肉芽肿性乳腺炎是一种罕见的乳腺良性疾病,分为特发性和特异性。临床和影像学诊断往往具有挑战性,因为它可以模拟恶性肿瘤。它具有多核巨细胞、非干酪化肉芽肿和坏死的组织学特征。治疗仍然存在争议,类固醇治疗作为主要的治疗方式,由于瘘管形成和复发而避免手术。目的:本研究旨在建立肉芽肿性乳腺炎的描述特征以及影响和导致该疾病复发的各种危险因素之间的相关性。材料和方法:这是一项在IBCC(综合乳房护理中心)进行的为期12个月的回顾性研究,该中心位于北阿坎德邦里希凯什的AIIMS。在就诊于OPD的2567例患者中,本研究中有34例患者被诊断为肉芽肿性乳腺炎。结果:34例以肉芽肿性乳房炎为临床表现的患者,平均年龄38.32岁,均为女性(100%),平均病程2.55个月。乳房肿块占82.4%,有疼痛占85.3%,有分泌物占17.6%。检查时,平均最大尺寸为3.41±1.15 cm, 67.6%有压痛。病理特征、巨细胞、AFB阳性、抗生素、类固醇、抗结核治疗与复发之间差异有统计学意义(P<0.05)。结论:肉芽肿性乳腺炎是一种类似恶性肿瘤的特殊疾病,但其转化率较低,但由于其慢性性导致生活质量差,给患者带来了更大的经济负担,这对这些患者来说是一种福音和灾难。
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引用次数: 0
Use of Humanoid Robot in Dementia Care: A Literature Review 类人机器人在痴呆护理中的应用:文献综述
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.249
R. Sather, Mahsa Soufineyestani, Arshia A. Khan, N. Imtiaz
Dementia is a prevalent age-related disease that affects an individual’s quality of life. Cognitive decline is the most common symptom of dementia that consequently causes problems with memory, language, and apathy, communication, thinking ability, difficulty in problem-solving and doing their daily living activities independently. In recent years, researchers have tried to improve the quality of life of people living with dementia by utilizing new technologies such as robots. This study aims to investigate specifically the application of humanoid robots in refuting the risk of dementia by focusing on three approaches: 1) cognitive-communication improvement, 2) psychomotor therapy, and 3) music therapy. The results indicate that having humanoid robots as companions may serve as an effective therapy that helps people living with dementia (PLwD) with their cognitive function, motor skills, language, and communication skill. It also may decrease psychiatric symptoms by involving PLwD which will lead to improvement in their quality of life. The humanoid robots can also help reduce cognitive decline by helping PLwD perform exercises.
痴呆症是一种流行的与年龄有关的疾病,会影响个人的生活质量。认知能力下降是痴呆症最常见的症状,从而导致记忆、语言、冷漠、沟通、思维能力、解决问题和独立进行日常生活活动的困难。近年来,研究人员试图通过利用机器人等新技术来改善痴呆症患者的生活质量。本研究旨在从认知-沟通改善、精神运动治疗和音乐治疗三个方面探讨类人机器人在抵御痴呆风险方面的应用。研究结果表明,人形机器人作为伴侣可能是一种有效的治疗方法,可以帮助痴呆症患者改善认知功能、运动技能、语言和沟通技能。它还可以通过涉及PLwD来减少精神症状,从而改善他们的生活质量。人形机器人还可以通过帮助PLwD进行锻炼来帮助减少认知能力下降。
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引用次数: 6
Healthy Aging Biology, Powerful Insight from the Long-Lived Naked Mole-Rat 健康的衰老生物学,来自长寿裸鼹鼠的有力洞察
Pub Date : 2021-01-01 DOI: 10.35248/2329-8847.21.9.258
F. Saldmann, M. Viltard, C. Leroy, P. Codogno, Gérard Friedl, Er
The naked mole-rat, Heterocephalus glaber, is the longest-lived rodent known with a lifespan in captivity >30 years, 10 times longer than mice, a comparable size rodent. In addition to a particularly long life, it exhibits exceptional resistance to many age-related diseases: cancer, cardiovascular, neurodegenerative, and metabolic diseases. It resists many forms of stress: hypoxia, oxidative stress, and strikingly maintains adequate body composition, fertility, bone quality, and mineral density throughout their long life. The naked mole-rat is a non-traditional animal model that defies the law governing the processes of aging and mortality and provides a powerful tool for the discovery of endogenous molecular anti-aging pathways. Over the past decades, much possible resistance and anti-aging mechanisms have been discovered. These include exclusive physiological mechanisms involved in cellular senescence and its clearance, telomere attrition, genome and proteome stability, stress resistance and metabolism flexibility… This review aims to summarize the many identified anti-aging strategies of the naked mole-rat to better grasp some of the main theories that have been generated. However, many of these theories remain to be fully investigated and confirmed to further understand the complex biology of the naked mole-rat.
裸鼹鼠(Heterocephalus glaber)是已知最长寿的啮齿动物,圈养的寿命约为30年,是同等大小的啮齿动物小鼠的10倍。除了特别长的寿命外,它还表现出对许多与年龄有关的疾病的特殊抵抗力:癌症、心血管疾病、神经退行性疾病和代谢疾病。它能抵抗多种形式的压力:缺氧、氧化应激,并在其漫长的一生中显著地保持足够的身体成分、生育能力、骨骼质量和矿物质密度。裸鼹鼠是一种非传统的动物模型,它违背了衰老和死亡过程的规律,为发现内源性分子抗衰老途径提供了有力的工具。在过去的几十年里,已经发现了许多可能的抵抗和抗衰老机制。其中包括细胞衰老及其清除的生理机制、端粒损耗、基因组和蛋白质组稳定性、抗逆性和代谢灵活性等。本文旨在总结目前已发现的许多裸鼹鼠抗衰老策略,以更好地掌握一些主要的理论。然而,这些理论中的许多仍有待充分研究和证实,以进一步了解裸鼹鼠的复杂生物学。
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Journal of aging science
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