首页 > 最新文献

Open journal of clinical & medical case reports最新文献

英文 中文
Epidemiological Research with Special Reference to Nuclear Worker Studies: Commentary 与核工作人员研究特别相关的流行病学研究:评论
Pub Date : 2021-01-01 DOI: 10.13188/2332-4120.1000038
Sergei V. Jargin
Limitations of some epidemiological studies on low-dose lowrate exposures to ionizing radiation include dose comparisons disregarding natural radiation background, unfounded classification of sporadic diseases as radiogenic and conclusions about causality of dose-effect relationships. Other bias, confounders and inter-study heterogeneity have been pointed out. Some dose-effect correlations can be explained by a dose-dependent selection, self-selection and recall bias. It can be reasonably assumed that individuals knowing their higher doses would be more motivated to undergo medical examinations being at the same time given more attention. Reported dose-effect relationships between low-dose low-rate exposures and non-neoplastic diseases call in question the causality of such relationships for cancer detected by the same researchers. Reliable evidence in regard to biological effects of low radiation doses can be obtained in large-scale animal experiments with registration of life duration. The monitoring of human populations exposed to low-dose radiation is important but conclusions should be made with caution considering potential bias and economical motives to strangulate nuclear energy production in accordance with the interests of fossil fuel producers. Of note, health burdens are the greatest for power stations based on coal and oil; the burdens are smaller for natural gas and still lower for the nuclear power. The same ranking applies for the greenhouse gas emissions
一些关于低剂量低速率电离辐射照射的流行病学研究的局限性包括:不考虑自然辐射本底的剂量比较、将散发疾病毫无根据地归类为辐射源性疾病以及关于剂量-效应关系因果关系的结论。还指出了其他偏倚、混杂因素和研究间异质性。一些剂量效应相关性可以用剂量依赖选择、自我选择和回忆偏倚来解释。可以合理地假设,知道自己的剂量较高的人会更有动力接受医学检查,同时得到更多的关注。已报告的低剂量低速率照射与非肿瘤性疾病之间的剂量效应关系,对同一研究人员发现的这种癌症关系的因果关系提出了质疑。关于低辐射剂量的生物效应,可以通过登记寿命的大规模动物实验获得可靠的证据。对暴露于低剂量辐射的人口进行监测是重要的,但应谨慎作出结论,考虑到根据化石燃料生产商的利益扼杀核能生产的潜在偏见和经济动机。值得注意的是,以煤和石油为基础的发电站的健康负担最大;天然气的负担更小,核能的负担更低。温室气体排放也是如此
{"title":"Epidemiological Research with Special Reference to Nuclear Worker Studies: Commentary","authors":"Sergei V. Jargin","doi":"10.13188/2332-4120.1000038","DOIUrl":"https://doi.org/10.13188/2332-4120.1000038","url":null,"abstract":"Limitations of some epidemiological studies on low-dose lowrate exposures to ionizing radiation include dose comparisons disregarding natural radiation background, unfounded classification of sporadic diseases as radiogenic and conclusions about causality of dose-effect relationships. Other bias, confounders and inter-study heterogeneity have been pointed out. Some dose-effect correlations can be explained by a dose-dependent selection, self-selection and recall bias. It can be reasonably assumed that individuals knowing their higher doses would be more motivated to undergo medical examinations being at the same time given more attention. Reported dose-effect relationships between low-dose low-rate exposures and non-neoplastic diseases call in question the causality of such relationships for cancer detected by the same researchers. Reliable evidence in regard to biological effects of low radiation doses can be obtained in large-scale animal experiments with registration of life duration. The monitoring of human populations exposed to low-dose radiation is important but conclusions should be made with caution considering potential bias and economical motives to strangulate nuclear energy production in accordance with the interests of fossil fuel producers. Of note, health burdens are the greatest for power stations based on coal and oil; the burdens are smaller for natural gas and still lower for the nuclear power. The same ranking applies for the greenhouse gas emissions","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"69 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72652794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Foreskin Retraction and Circumcision: Possible Late Consequences 包皮缩回和包皮环切术:可能的后期后果
Pub Date : 2021-01-01 DOI: 10.13188/2332-4120.1000040
Sergei V. Jargin
This case report is about spontaneous foreskin retraction but it is relevant also to the status after circumcision. Non-therapeutic male circumcision remains controversial; there is evidence in support of its benefits; however, good hygiene may achieve some of the aims. Late consequences are understudied, in particular, those related to atrophy of the ageing genital skin and mucous membranes. A superficial scald burn of the genital area occurred to a 3-years-old boy in conditions of child neglect. Immediate medical help was not sought. In the following years, symptoms of balanoposthitis were repeatedly noticed. Along with the pubertal development, the foreskin became completely and permanently retracted. There has never been any strangulation or compression in terms of paraphimosis. The symptoms started appearing at the age of about 58 years: recurring superficial erosions in the frenular area, preputial rim and adjacent surfaces. The penis binding with a soft cloth and occasional topical treatment is necessary as atrophic skin is sensitive and vulnerable. Derangements of blood supply may contribute to atrophic changes; therefore, vascular diseases and diabetes mellitus must be included in the differential diagnosis. Potential adverse effects discussed in this report emphasize the fact that non-therapeutic neonatal circumcision is an invasive procedure performed without patients’ consent.
本病例报告是关于自发性包皮回缩,但也与包皮环切术后的状态有关。非治疗性男性包皮环切术仍然存在争议;有证据支持它的好处;然而,良好的卫生习惯可能会达到一些目的。晚期的后果尚未得到充分研究,特别是那些与老化的生殖器皮肤和粘膜萎缩有关的后果。一个三岁的男孩在被忽视的情况下生殖器区域发生了浅表烫伤。没有立即寻求医疗帮助。在接下来的几年里,balanpothitis的症状被反复发现。随着青春期的发育,包皮完全和永久地缩回。在寄生虫病方面,从来没有任何勒死或压迫。症状在大约58岁时开始出现:系带区、包皮边缘和邻近表面反复出现浅表糜烂。阴茎用软布包扎,偶尔局部治疗是必要的,因为萎缩的皮肤是敏感和脆弱的。血液供应紊乱可能导致萎缩性变化;因此,血管疾病和糖尿病必须纳入鉴别诊断。本报告中讨论的潜在不良反应强调了一个事实,即非治疗性新生儿包皮环切术是一种未经患者同意的侵入性手术。
{"title":"Foreskin Retraction and Circumcision: Possible Late Consequences","authors":"Sergei V. Jargin","doi":"10.13188/2332-4120.1000040","DOIUrl":"https://doi.org/10.13188/2332-4120.1000040","url":null,"abstract":"This case report is about spontaneous foreskin retraction but it is relevant also to the status after circumcision. Non-therapeutic male circumcision remains controversial; there is evidence in support of its benefits; however, good hygiene may achieve some of the aims. Late consequences are understudied, in particular, those related to atrophy of the ageing genital skin and mucous membranes. A superficial scald burn of the genital area occurred to a 3-years-old boy in conditions of child neglect. Immediate medical help was not sought. In the following years, symptoms of balanoposthitis were repeatedly noticed. Along with the pubertal development, the foreskin became completely and permanently retracted. There has never been any strangulation or compression in terms of paraphimosis. The symptoms started appearing at the age of about 58 years: recurring superficial erosions in the frenular area, preputial rim and adjacent surfaces. The penis binding with a soft cloth and occasional topical treatment is necessary as atrophic skin is sensitive and vulnerable. Derangements of blood supply may contribute to atrophic changes; therefore, vascular diseases and diabetes mellitus must be included in the differential diagnosis. Potential adverse effects discussed in this report emphasize the fact that non-therapeutic neonatal circumcision is an invasive procedure performed without patients’ consent.","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83924229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Five Year Mortality Trend Among Bushehr Nuclear Plant Workers Exposed To Ionizing Radiation: Does Sanction Impact Mortality Rate? 布什尔核电站电离辐射工人5年死亡率趋势:制裁会影响死亡率吗?
Pub Date : 2021-01-01 DOI: 10.13188/2332-4120.1000039
H. Abolghasemi
Background: The investigation of potential adverse health effects of occupational exposures to ionizing radiation, on nuclear plant workers, is an important area of research. In this study, we aimed to calculate the incidence and risk of cancer development and mortality during last five years (2015-2019). Material and Methods: 660 nuclear industry workers were included into this study. For this cohort, the cancer mortality has been assessed by data obtained from national health registry excluded for the probability of known causes of death. The associations between cumulative occupational radiation exposures (radon, gamma radiation and long-lived radionuclides) and cancer mortality were calculated. Results: Radon and Gamma exposure, in mSV, was significantly higher among workers who developed cancer [8.9 (0; 3,224.5) vs 19.9 (0; 128.4), p=0.03] and [15.0 (2.1; 110.0) vs 24.5 (0; 470.1), p=0.02]. However, no significant association was found between long-lived radionuclides and risk of cancer (p=0.07). Considering economic sanction as a dependent variable, we found no significant effect on mortality rate among workers. Conclusion: In conclusion, significant association has been observed between the risk of cancer development and radon and gamma exposure among nuclear industry workers, but no association was found between cancer and long-live nucleoids exposure.
背景:职业性暴露于电离辐射对核电厂工作人员健康的潜在不利影响的调查是一个重要的研究领域。在本研究中,我们旨在计算过去五年(2015-2019)癌症发展和死亡率的发病率和风险。材料与方法:以660名核工业工人为研究对象。对于这一队列,癌症死亡率通过从国家健康登记处获得的数据进行评估,排除了已知死亡原因的概率。计算了累积职业辐射暴露(氡、伽马辐射和长寿命放射性核素)与癌症死亡率之间的关系。结果:在mSV中,患癌症的工人的氡和伽马暴露明显更高[8.9 (0;3,224.5) vs 19.9 (0;128.4), p=0.03]和[15.0 (2.1;110.0 vs 24.5 (0;470.1), p = 0.02)。然而,没有发现长寿命放射性核素与癌症风险之间的显著关联(p=0.07)。考虑到经济制裁作为因变量,我们发现对工人死亡率没有显著影响。结论:在核工业工人中,氡和伽马暴露与癌症发生风险之间存在显著关联,但与长期类核暴露之间没有关联。
{"title":"Five Year Mortality Trend Among Bushehr Nuclear Plant Workers Exposed To Ionizing Radiation: Does Sanction Impact Mortality Rate?","authors":"H. Abolghasemi","doi":"10.13188/2332-4120.1000039","DOIUrl":"https://doi.org/10.13188/2332-4120.1000039","url":null,"abstract":"Background: The investigation of potential adverse health effects of occupational exposures to ionizing radiation, on nuclear plant workers, is an important area of research. In this study, we aimed to calculate the incidence and risk of cancer development and mortality during last five years (2015-2019). Material and Methods: 660 nuclear industry workers were included into this study. For this cohort, the cancer mortality has been assessed by data obtained from national health registry excluded for the probability of known causes of death. The associations between cumulative occupational radiation exposures (radon, gamma radiation and long-lived radionuclides) and cancer mortality were calculated. Results: Radon and Gamma exposure, in mSV, was significantly higher among workers who developed cancer [8.9 (0; 3,224.5) vs 19.9 (0; 128.4), p=0.03] and [15.0 (2.1; 110.0) vs 24.5 (0; 470.1), p=0.02]. However, no significant association was found between long-lived radionuclides and risk of cancer (p=0.07). Considering economic sanction as a dependent variable, we found no significant effect on mortality rate among workers. Conclusion: In conclusion, significant association has been observed between the risk of cancer development and radon and gamma exposure among nuclear industry workers, but no association was found between cancer and long-live nucleoids exposure.","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89491465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coincidence of Tender Facial Swelling and Painful Calf Lesions in a 23 Year Old Woman 一例23岁女性面部柔软肿胀和小腿疼痛病变的巧合
Pub Date : 2019-12-30 DOI: 10.13188/2332-4120.1000036
Idan Blum, Zamir Doron
A 23 year old female was admitted to Internal Medicine department due to bilateral face swelling of both preauricular area and multiple tender small lesions in the anterior aspect of both calves. A few similar lesions were found on the posterior aspect of her arms. She had a prodrome of two days fever before and upper dysphagia and odynophagia a day before her admission. She reported of mild alcohol consumption and childhood asthma. She did not take any medication prior to her admission except oral contraceptives, which were prescribed for a few weeks, until 4 months ago. On physical examination, the patient seemed to have bilateral tender swellings of both preauricularareas ,that were painful while opening her mouth (Figure 1). She also had bilateral tender erythematous lesions on both calves and a few similar lesions involving the extensor portion of her arms (Figure 2). The lesion borders were poorly defined, and lesions vary from 2-5 cm. The rest of physical examination was within the normal range. Laboratory examination included elevated CRP (133 mg/dL, norm<0.5 mg/dL). CBC, liver functions and renal functions were all within the normal range. Blood cultures, serology for HAV, HBV, HCV, EBV, CMV and HIV and Mantoux test were negative. Antinuclear antibody was weak positive (+1), complement levels (c3 & c4) were in normal range and Rheumatoid Factor was negative. Beta HCG was negative (<0.6). Chest X-ray was without pathologic findings.
一名23岁女性因双侧面部双耳前区肿胀和双小腿前部多发小嫩痛病变入院内科。在她的手臂后部发现了一些类似的病变。患者入院前有发热2天的前驱症状,入院前1天出现上颌吞咽困难和吞咽困难。她报告有轻度饮酒和儿童哮喘。入院前未服用任何药物,只开了几周的口服避孕药,直到4个月前。体格检查显示,患者双侧耳廓前区有压痛性肿胀,开口时感到疼痛(图1)。患者双侧小腿也有压痛性红斑病变,手臂伸肌部分也有一些类似病变(图2)。病变边界不清,病变范围为2-5厘米。其余体检均在正常范围内。实验室检查CRP升高(133 mg/dL,正常值<0.5 mg/dL)。全血细胞计数、肝功能、肾功能均在正常范围内。血培养、HAV、HBV、HCV、EBV、CMV、HIV血清学及Mantoux检测均为阴性。抗核抗体弱阳性(+1),补体水平(c3、c4)正常,类风湿因子阴性。β HCG为阴性(<0.6)。胸片未见病理表现。
{"title":"Coincidence of Tender Facial Swelling and Painful Calf Lesions in a 23 Year Old Woman","authors":"Idan Blum, Zamir Doron","doi":"10.13188/2332-4120.1000036","DOIUrl":"https://doi.org/10.13188/2332-4120.1000036","url":null,"abstract":"A 23 year old female was admitted to Internal Medicine department due to bilateral face swelling of both preauricular area and multiple tender small lesions in the anterior aspect of both calves. A few similar lesions were found on the posterior aspect of her arms. She had a prodrome of two days fever before and upper dysphagia and odynophagia a day before her admission. She reported of mild alcohol consumption and childhood asthma. She did not take any medication prior to her admission except oral contraceptives, which were prescribed for a few weeks, until 4 months ago. On physical examination, the patient seemed to have bilateral tender swellings of both preauricularareas ,that were painful while opening her mouth (Figure 1). She also had bilateral tender erythematous lesions on both calves and a few similar lesions involving the extensor portion of her arms (Figure 2). The lesion borders were poorly defined, and lesions vary from 2-5 cm. The rest of physical examination was within the normal range. Laboratory examination included elevated CRP (133 mg/dL, norm<0.5 mg/dL). CBC, liver functions and renal functions were all within the normal range. Blood cultures, serology for HAV, HBV, HCV, EBV, CMV and HIV and Mantoux test were negative. Antinuclear antibody was weak positive (+1), complement levels (c3 & c4) were in normal range and Rheumatoid Factor was negative. Beta HCG was negative (<0.6). Chest X-ray was without pathologic findings.","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83944591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Small Bowel Lymphangioma - A Rare Cause of Small Bowel Bleeding 小肠淋巴管瘤-小肠出血的罕见原因
Pub Date : 2018-06-30 DOI: 10.13188/2332-4120.1000034
Cassandra D. L. Fritz, G. Lang
Lymphangiomas represent benign embryonic vascular malformations of the lymphatic architecture. A symptomatic small bowel lymphangioma in an adult is a rare finding. Here we present a case of a 93 year-old male who had a 3-month history of intermittent melena. After an unrevealing upper endoscopy, colonoscopy was significant for blood emanating from the ileo-cecal valve. Video capsule endoscopy was significant for bright blood and clots in jejunum. Small bowel enteroscopy demonstrated multiple jejunal sub-mucosal masses. The bleeding lesion was biopsied and then successfully treated with Argon Plasma Coagulation (APC). Histopathology was consistent with a lymphangioma.
淋巴管瘤是淋巴管结构的良性胚胎血管畸形。成人有症状的小肠淋巴管瘤是一种罕见的发现。在这里,我们提出一个病例93岁的男性谁有3个月的间歇性黑黑病史。在未显露的上腔内镜检查后,结肠镜检查对从回盲肠瓣膜流出的血液有重要意义。视频胶囊内窥镜对空肠亮血和凝块有重要意义。小肠肠镜检查显示空肠黏膜下多发肿块。对出血灶进行活检,并用氩等离子凝血(APC)成功治疗。组织病理学符合淋巴管瘤。
{"title":"Small Bowel Lymphangioma - A Rare Cause of Small Bowel Bleeding","authors":"Cassandra D. L. Fritz, G. Lang","doi":"10.13188/2332-4120.1000034","DOIUrl":"https://doi.org/10.13188/2332-4120.1000034","url":null,"abstract":"Lymphangiomas represent benign embryonic vascular malformations of the lymphatic architecture. A symptomatic small bowel lymphangioma in an adult is a rare finding. Here we present a case of a 93 year-old male who had a 3-month history of intermittent melena. After an unrevealing upper endoscopy, colonoscopy was significant for blood emanating from the ileo-cecal valve. Video capsule endoscopy was significant for bright blood and clots in jejunum. Small bowel enteroscopy demonstrated multiple jejunal sub-mucosal masses. The bleeding lesion was biopsied and then successfully treated with Argon Plasma Coagulation (APC). Histopathology was consistent with a lymphangioma.","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88474517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Alcohol Abuse, Reproductive Coercion and Intimate Partner Violence: Case Reports and Mini-Review 酒精滥用、生殖强迫和亲密伴侣暴力:案例报告和小型审查
Pub Date : 2018-06-30 DOI: 10.13188/2332-4120.1000033
Sergei V. Jargin, S. Jargin
This article presents a continuation of report series on alcohol abuse, reproductive coercion and intimate partner violence. Abortion rate in the former Soviet Union has been the highest in the world, caused not only by the insufficient availability of modern contraception but also by irresponsible behavior. The overconsumption of alcohol is generally perceived as a contributing factor. Currently there is an improvement tendency. The social background of certain behavioral stereotypes such as reproductive coercion and binge drinking are discussed. The conclusion is that use of condoms is dependent on personal traits and the level of social development; however, alcohol consumption at sexual encounters and heavy binge drinking are risk factors for the non-use of condoms and other irresponsible behaviors. Citation: Jargin SV. Alcohol Abuse, Reproductive Coercion and Intimate Partner Violence: Case Reports and Mini-Review. J Clin Med Case Reports. 2018;5(1): 5. J Clin Med Case Reports 5(1): 5 (2018) Page 02 ISSN: 2332-4120 family. The officer had a 20-years-old son, who (together with his friend) sexually assaulted the visiting mother’s cousin. Two years later the officer’s son married the victim, who was pregnant at that time. Under conditions of the Soviet registration system, aimed to counteract mass migration to the capital, factual and fictive marriages were used to be registered in Moscow. It is known that one of the reasons for women to remain with their assailants can be shortage of community resources such as the legal assistance and social support [15]. In the former SU, the registration and accommodation have been strong motives especially for Moscow and other cities attracting migrants. In some less developed societies with a widespread rape myth acceptance, sexual violence was a way of acquiring wives [15,16]. The fact that some victims married rapists was seen as indication that women enjoy it; in fact, however, existing accounts demonstrate various degrees of trauma [16]. High social positions held by sexual offenders or their relatives sometimes impede reporting [15]. Later on, the stepfather physically abused his stepson, while the mother sometimes participated in battering.
本文是关于酗酒、强迫生育和亲密伴侣暴力的系列报告的延续。前苏联的堕胎率一直是世界上最高的,这不仅是因为现代避孕手段不足,还因为不负责任的行为。过度饮酒通常被认为是一个促成因素。目前有改善的趋势。讨论了生育强迫和酗酒等行为刻板印象产生的社会背景。结论:避孕套的使用与个人特征和社会发展水平有关;然而,性接触中饮酒和酗酒是不使用避孕套和其他不负责任行为的危险因素。引用本文:行话SV酒精滥用、生殖强迫和亲密伴侣暴力:案例报告和小型审查。临床医学病例报告,2018;5(1):5。J临床医学病例报告5(1):5(2018)Page 02 ISSN: 2332-4120 family。这名警官有一个20岁的儿子,他(和他的朋友)性侵了来访母亲的堂兄。两年后,这名警官的儿子娶了当时怀孕的受害者。在苏联登记制度的条件下,旨在抵制大规模移民到首都,事实和虚构的婚姻都是在莫斯科登记的。众所周知,妇女继续与攻击者在一起的原因之一可能是缺乏社区资源,如法律援助和社会支持bb0。在前苏联,登记和住宿一直是吸引移民的强烈动机,尤其是莫斯科和其他城市。在一些普遍接受强奸神话的欠发达社会,性暴力是获得妻子的一种方式[15,16]。一些受害者与强奸犯结婚的事实被视为女性喜欢这样做的迹象;然而,事实上,现有的账目显示出不同程度的创伤。性犯罪者或其亲属所处的较高社会地位有时会阻碍举报。后来,继父在身体上虐待他的继子,而母亲有时也参与殴打。
{"title":"Alcohol Abuse, Reproductive Coercion and Intimate Partner Violence: Case Reports and Mini-Review","authors":"Sergei V. Jargin, S. Jargin","doi":"10.13188/2332-4120.1000033","DOIUrl":"https://doi.org/10.13188/2332-4120.1000033","url":null,"abstract":"This article presents a continuation of report series on alcohol abuse, reproductive coercion and intimate partner violence. Abortion rate in the former Soviet Union has been the highest in the world, caused not only by the insufficient availability of modern contraception but also by irresponsible behavior. The overconsumption of alcohol is generally perceived as a contributing factor. Currently there is an improvement tendency. The social background of certain behavioral stereotypes such as reproductive coercion and binge drinking are discussed. The conclusion is that use of condoms is dependent on personal traits and the level of social development; however, alcohol consumption at sexual encounters and heavy binge drinking are risk factors for the non-use of condoms and other irresponsible behaviors. Citation: Jargin SV. Alcohol Abuse, Reproductive Coercion and Intimate Partner Violence: Case Reports and Mini-Review. J Clin Med Case Reports. 2018;5(1): 5. J Clin Med Case Reports 5(1): 5 (2018) Page 02 ISSN: 2332-4120 family. The officer had a 20-years-old son, who (together with his friend) sexually assaulted the visiting mother’s cousin. Two years later the officer’s son married the victim, who was pregnant at that time. Under conditions of the Soviet registration system, aimed to counteract mass migration to the capital, factual and fictive marriages were used to be registered in Moscow. It is known that one of the reasons for women to remain with their assailants can be shortage of community resources such as the legal assistance and social support [15]. In the former SU, the registration and accommodation have been strong motives especially for Moscow and other cities attracting migrants. In some less developed societies with a widespread rape myth acceptance, sexual violence was a way of acquiring wives [15,16]. The fact that some victims married rapists was seen as indication that women enjoy it; in fact, however, existing accounts demonstrate various degrees of trauma [16]. High social positions held by sexual offenders or their relatives sometimes impede reporting [15]. Later on, the stepfather physically abused his stepson, while the mother sometimes participated in battering.","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75430006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Denture Tumor: The Uninvited Distress amongst the Geriatrics - A Case Report 义齿肿瘤:不请自来的痛苦在老年人-一个病例报告
Pub Date : 2018-06-30 DOI: 10.13188/2332-4120.1000035
Dentures are prosthetic devices constructed to aid as a replacement for the missing teeth. However, the problems come when there is no right fitting as it can turn into a potpourri of problems for the patient. Discomfort in mastication, speech, pain and inflammation are just some of the ill-effects of an ill-fitting denture. Epulis fissuratum refers to reactive tissue response to excessive mechanical pressure imparted by the poor fit of prosthesis. In this article, we discuss one such case of a 63-year-old female. Figure 1: A) Partially edentulous mandibular arch with grossly decayed teeth and root stumps. B) Epulis fissuratum in relation to the maxillary anterior labial and alveolar mucosa. Citation: Kamakshi, Geon Pauly N, Rao PK, Kashyap RR, Bhandarkar GP, et al. Denture Tumor: The Uninvited Distress amongst the Geriatrics A Case Report. J Clin Med Case Reports. 2018;5(1): 2. J Clin Med Case Reports 5(1): 2 (2018) Page 02 ISSN: 2332-4120 EF can be treated surgically or conservatively. In the early stage, denture coverage with a soft liner material is frequently sufficient for elimination or reduction of the lesion. However, in later stages, when the hyperplastic tissue is composed of significant fibrosis, surgical excision is the treatment of choice [8]. Surgical options include scalpel biopsy or carbon dioxide laser excision. This is followed by fabrication of a new set of adequately fitting dentures [9]. In a recent case report, the use of liquid nitrogen cryosurgery has been suggested to manage epulis fissuratum in geriatric patients [8].
假牙是一种修复装置,用来代替缺失的牙齿。然而,当没有合适的合适的时候,问题就来了,因为它可能会变成病人的各种问题。咀嚼不适,说话,疼痛和炎症只是假牙不合适的一些不良影响。骨裂是指由于假体不合适而造成的过度机械压力引起的反应性组织反应。在本文中,我们将讨论一位63岁的女性。图1:A)部分无牙的下颌弓,牙齿和根残端严重腐烂。B)上唇裂肌与上颌前唇和牙槽黏膜的关系。引用本文:Kamakshi, Geon Pauly N, Rao PK, Kashyap RR, Bhandarkar GP等。义齿肿瘤:老年人不期而遇的痛苦1例报告。临床医学病例报告,2018;5(1):2。J临床医学病例报告5(1):2 (2018)Page 02 ISSN: 2332-4120 EF可以手术或保守治疗。在早期阶段,用软衬材料覆盖义齿通常足以消除或减少病变。然而,在晚期,当增生组织由明显的纤维化组成时,手术切除是治疗的选择[8]。手术选择包括手术刀活检或二氧化碳激光切除。接下来是制作一套新的合适的假牙[9]。在最近的一份病例报告中,建议使用液氮冷冻手术来治疗老年患者的上睑裂[8]。
{"title":"Denture Tumor: The Uninvited Distress amongst the Geriatrics - A Case Report","authors":"","doi":"10.13188/2332-4120.1000035","DOIUrl":"https://doi.org/10.13188/2332-4120.1000035","url":null,"abstract":"Dentures are prosthetic devices constructed to aid as a replacement for the missing teeth. However, the problems come when there is no right fitting as it can turn into a potpourri of problems for the patient. Discomfort in mastication, speech, pain and inflammation are just some of the ill-effects of an ill-fitting denture. Epulis fissuratum refers to reactive tissue response to excessive mechanical pressure imparted by the poor fit of prosthesis. In this article, we discuss one such case of a 63-year-old female. Figure 1: A) Partially edentulous mandibular arch with grossly decayed teeth and root stumps. B) Epulis fissuratum in relation to the maxillary anterior labial and alveolar mucosa. Citation: Kamakshi, Geon Pauly N, Rao PK, Kashyap RR, Bhandarkar GP, et al. Denture Tumor: The Uninvited Distress amongst the Geriatrics A Case Report. J Clin Med Case Reports. 2018;5(1): 2. J Clin Med Case Reports 5(1): 2 (2018) Page 02 ISSN: 2332-4120 EF can be treated surgically or conservatively. In the early stage, denture coverage with a soft liner material is frequently sufficient for elimination or reduction of the lesion. However, in later stages, when the hyperplastic tissue is composed of significant fibrosis, surgical excision is the treatment of choice [8]. Surgical options include scalpel biopsy or carbon dioxide laser excision. This is followed by fabrication of a new set of adequately fitting dentures [9]. In a recent case report, the use of liquid nitrogen cryosurgery has been suggested to manage epulis fissuratum in geriatric patients [8].","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91263035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tinnitus, Oscillopsia, and Hyperventilation-Induced Nystagmus: Vestibular Paroxysmia. 耳鸣、震颤和过度通气引起的眼球震颤:前庭阵发性震颤。
Bryan K Ward, Daniel R Gold

Vestibular paroxysmia is the name given to vascular compression of the vestibulocochlear nerve. Substantial evidence has been discovered in support of vascular compression of the trigeminal nerve as the etiology for trigeminal neuralgia, and effective therapies have been targeted to address this pathophysiology. Perhaps due to the common and often vaguely-described symptoms of dizziness and tinnitus, vascular compression of the vestibulocochlear nerve as a cause of symptoms has remained controversial. Recent clinical studies, however, have better defined diagnostic criteria for vestibular paroxysmia. In this report we discuss a case of vestibular paroxysmia, highlighting some findings of the condition that also uniquely separate it from other more common vestibular disorders. Finally, we discuss current clinical management of vestibular paroxysmia.

前庭阵发性发作是指前庭耳蜗神经受到血管压迫。大量证据已经发现支持血管压迫三叉神经作为三叉神经痛的病因,有效的治疗已经针对这一病理生理。也许是由于头晕和耳鸣的常见症状和经常模糊描述的症状,血管压迫前庭耳蜗神经作为症状的原因仍然存在争议。然而,最近的临床研究对前庭阵发性发作有了更好的诊断标准。在本报告中,我们讨论一个前庭阵发性发作的病例,强调一些发现的条件,也独特地将其与其他更常见的前庭疾病分开。最后,我们讨论目前前庭阵发性发作的临床处理。
{"title":"Tinnitus, Oscillopsia, and Hyperventilation-Induced Nystagmus: Vestibular Paroxysmia.","authors":"Bryan K Ward,&nbsp;Daniel R Gold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Vestibular paroxysmia is the name given to vascular compression of the vestibulocochlear nerve. Substantial evidence has been discovered in support of vascular compression of the trigeminal nerve as the etiology for trigeminal neuralgia, and effective therapies have been targeted to address this pathophysiology. Perhaps due to the common and often vaguely-described symptoms of dizziness and tinnitus, vascular compression of the vestibulocochlear nerve as a cause of symptoms has remained controversial. Recent clinical studies, however, have better defined diagnostic criteria for vestibular paroxysmia. In this report we discuss a case of vestibular paroxysmia, highlighting some findings of the condition that also uniquely separate it from other more common vestibular disorders. Finally, we discuss current clinical management of vestibular paroxysmia.</p>","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"2 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4857855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34465620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Low-Resolution Electromagnetic Tomography (LORETA) of changed Brain Function Provoked by Pro-Dopamine Regulator (KB220z) in one Adult ADHD case. 低分辨率电磁断层扫描(LORETA)对1例成人ADHD病例中亲多巴胺调节剂(KB220z)引起的脑功能改变的研究
Bruce Steinberg, Kenneth Blum, Thomas McLaughlin, Joel Lubar, Marcelo Febo, Eric R Braverman, Rajendra D Badgaiyan

Attention Deficit-Hyperactivity Disorder (ADHD) often continues into adulthood. Recent neuroimaging studies found lowered baseline dopamine tone in the brains of affected individuals that may place them at risk for Substance Use Disorder (SUD). This is an observational case study of the potential for novel management of Adult ADHD with a non-addictive glutaminergic-dopaminergic optimization complex KB200z. Low-resolution electromagnetic tomography (LORETA) was used to evaluate the effects of KB220z on a 72-year-old male with ADHD, at baseline and one hour following administration. The resultant z-scores, averaged across Eyes Closed, Eyes Open and Working Memory conditions, increased for each frequency band, in the anterior, dorsal and posterior cingulate regions, as well as the right dorsolateral prefrontal cortex during Working Memory, with KB220z. These scores are consistent with other human and animal neuroimaging studies that demonstrated increased connectivity volumes in reward circuitry and may offer a new approach to ADHD treatment. However, larger randomized trials to confirm these results are required.

注意缺陷多动障碍(ADHD)通常会持续到成年。最近的神经影像学研究发现,受影响的个体大脑中多巴胺的基线张力降低,可能使他们面临物质使用障碍(SUD)的风险。这是一项观察性案例研究,研究了非成瘾性谷氨酰胺能-多巴胺能优化复合物KB200z对成人ADHD的新治疗潜力。低分辨率电磁断层扫描(LORETA)用于评估KB220z在基线和给药后1小时对72岁ADHD男性的影响。结果显示,在工作记忆过程中,使用KB220z,闭眼、睁眼和工作记忆条件下的平均z分数在每个频带的前、背、后扣带区以及右侧背外侧前额叶皮层都有所增加。这些分数与其他人类和动物神经成像研究一致,这些研究表明奖赏回路的连接量增加,可能为ADHD治疗提供一种新的方法。然而,需要更大规模的随机试验来证实这些结果。
{"title":"Low-Resolution Electromagnetic Tomography (LORETA) of changed Brain Function Provoked by Pro-Dopamine Regulator (KB220z) in one Adult ADHD case.","authors":"Bruce Steinberg,&nbsp;Kenneth Blum,&nbsp;Thomas McLaughlin,&nbsp;Joel Lubar,&nbsp;Marcelo Febo,&nbsp;Eric R Braverman,&nbsp;Rajendra D Badgaiyan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Attention Deficit-Hyperactivity Disorder (ADHD) often continues into adulthood. Recent neuroimaging studies found lowered baseline dopamine tone in the brains of affected individuals that may place them at risk for Substance Use Disorder (SUD). This is an observational case study of the potential for novel management of Adult ADHD with a non-addictive glutaminergic-dopaminergic optimization complex KB200z. Low-resolution electromagnetic tomography (LORETA) was used to evaluate the effects of KB220z on a 72-year-old male with ADHD, at baseline and one hour following administration. The resultant z-scores, averaged across Eyes Closed, Eyes Open and Working Memory conditions, increased for each frequency band, in the anterior, dorsal and posterior cingulate regions, as well as the right dorsolateral prefrontal cortex during Working Memory, with KB220z. These scores are consistent with other human and animal neuroimaging studies that demonstrated increased connectivity volumes in reward circuitry and may offer a new approach to ADHD treatment. However, larger randomized trials to confirm these results are required.</p>","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2016-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5012539/pdf/nihms813497.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34376041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Coronary Syndrome In HIV Naïve Patient With Low CD4 Count And No Other Significant Risk Factors: Case Report And Literature Review. CD4计数低且无其他显著危险因素的HIV患者Naïve急性冠脉综合征病例报告及文献复习
Zaher Fanari, Sumaya Hammami, Muhammad Baraa Hammami, William S Weintraub, Wasif A Qureshi

Coronary artery disease (CAD) has become the leading cause of mortality in patients with Human Immunodeficiency Virus (HIV). The typical HIV-infected patient presenting with acute coronary syndrome (ACS) is a man in his mid to late 40s. The most common presentation is an acute myocardial infarction (MI), most often with ST segment elevation. Coronary anatomy seems to be variable, with some studies showing a higher prevalence of single-vessel disease and others showing a higher prevalence of 2- and 3-vessel disease than in controls not infected with HIV.

冠状动脉疾病(CAD)已成为人类免疫缺陷病毒(HIV)患者死亡的主要原因。以急性冠状动脉综合征(ACS)为表现的典型hiv感染者是40多岁至40多岁的男性。最常见的表现是急性心肌梗死(MI),最常伴有ST段抬高。冠状动脉解剖结构似乎是可变的,一些研究显示单血管疾病的患病率较高,而另一些研究显示两支和三支血管疾病的患病率高于未感染艾滋病毒的对照组。
{"title":"Acute Coronary Syndrome In HIV Naïve Patient With Low CD4 Count And No Other Significant Risk Factors: Case Report And Literature Review.","authors":"Zaher Fanari,&nbsp;Sumaya Hammami,&nbsp;Muhammad Baraa Hammami,&nbsp;William S Weintraub,&nbsp;Wasif A Qureshi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coronary artery disease (CAD) has become the leading cause of mortality in patients with Human Immunodeficiency Virus (HIV). The typical HIV-infected patient presenting with acute coronary syndrome (ACS) is a man in his mid to late 40s. The most common presentation is an acute myocardial infarction (MI), most often with ST segment elevation. Coronary anatomy seems to be variable, with some studies showing a higher prevalence of single-vessel disease and others showing a higher prevalence of 2- and 3-vessel disease than in controls not infected with HIV.</p>","PeriodicalId":90942,"journal":{"name":"Open journal of clinical & medical case reports","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2015-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4459740/pdf/nihms688042.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33259668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Open journal of clinical & medical case reports
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1