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Investigating the Concomitant Removal of Hydrocarbons and Heavy Metals by highly adapted Bacillus and Pseudomonas strains 研究高适应性芽孢杆菌和假单胞菌菌株对碳氢化合物和重金属的同时去除
Pub Date : 2021-10-28 DOI: 10.29117/quarfe.2021.0027
Zulfa Aldisi, Mohammad Alghouti, N. Zouari
This study investigates the concomitant removal of hydrocarbons and heavy metals by highly adapted Bacillus and Pseudomonas strains. In regions characterized by harsh conditions such as Qatar, the weathering processes would affect the content, status, and distribution of these contaminants. It was shown in the weathered soil from Dukhan oil wastes dumpsite that 14 heavy metals exceeded the EPA limits. Moreover, it was demonstrated that soil organics did not affect the distribution of the metals in the soil. However, most of the heavy metals were strongly bonded to the residual and the iron-manganese oxide fractions. Eighteen bacterial strains isolated from highly weathered oily soils were able to grow with heavy metal concentrations up to 3 mM and above for some. Seven selected strains (4 Bacillus and 3 Pseudomonas) showed the ability to remove almost 60 to 70% of most of the heavy metals when used at 1 mM. Moreover, they removed up to 75% of the diesel range organics. These results are of interest for selecting bacterial strains, which can overcome the toxicity of hydrocarbons and heavy metals and remove them concomitantly.
本研究探讨了高适应性芽孢杆菌和假单胞菌菌株对碳氢化合物和重金属的同时去除。在卡塔尔等条件恶劣的地区,风化过程会影响这些污染物的含量、状态和分布。在Dukhan石油废渣堆积场的风化土壤中,有14种重金属超标。此外,土壤有机质不影响金属在土壤中的分布。然而,大部分重金属都与残余和铁锰氧化物组分紧密结合。从高度风化的油质土壤中分离出的18株细菌能够在重金属浓度高达3毫米及以上的环境中生长。7个选定的菌株(4个芽孢杆菌和3个假单胞菌)在1毫米的浓度下显示出去除大多数重金属近60 - 70%的能力。此外,它们可以去除高达75%的柴油范围有机物。这些结果对于选择能够克服碳氢化合物和重金属的毒性并同时去除它们的菌株具有重要意义。
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引用次数: 0
Exploring QU Health Students' Experiences of Burnout, Anxiety, and Empathy during the COVID-19 Pandemic: A Mixed Method Study 新冠肺炎大流行期间QU健康学生倦怠、焦虑和共情体验的混合方法研究
Pub Date : 2021-10-28 DOI: 10.29117/quarfe.2021.0131
Ruba Sulaiman, S. Ismail, M. ElHajj, Mujahed Shraim, T. Kane, A. El-Awaisi
Background Students' mental health is a growing concern. COVID-19 pandemic resulted in academic and non-academic challenges which caused students' burnout, anxiety, and reduced empathy. Objectives The study objectives were to assess burnout amongst QU Health students, determine the relationship between burnout and anxiety, and burnout and empathy, and to determine the students coping strategies. Methods A convergent mixed-methods design was used: (1) a cross-sectional survey using validated instruments. Maslach Burnout Inventory-General Students Survey (MBI-GS(S)) to measure burnout, Generalized Anxiety Disorder 7-item Scale (GAD-7) to measure anxiety, and Interpersonal Reactivity Index (IRI) to measure empathy; (2) focus groups to get a deeper insight of the students' experiences and coping strategies. Descriptive and multivariate statistical analyses were used for the survey while the focus groups were analysed using deductive thematic analysis following the coping reserve model. Results 21.45% of students responded to the survey. Burnout was reported according to the subscales. MBI-Exhaustion (MBI-EX) subscale (mean= 4.07, SD= 1.56), MBI-Cynicism (MBI-CY) subscale (mean= 2.63, SD= 1.53), and MBI-Professional Efficacy (MBI-PE) subscale (mean= 3.97, SD= 1.22). MBI-EX and MBI-CY were associated with GAD-7 scores. MBI-EX and MBI-CY were associated with IRI-Empathic Concern (IRI-EC) and IRI-Personal Distress (IRI-PD) while MBI-PE was associated with IRI-Perspective Talking (IRI-PT) and IRI-EC. The students used many coping strategies to build resilience. Conclusion QU Health students experienced burnout during the spring 2020 semester. Many burnout causes and coping strategies were identified. It is suggested for QU to start mentorship programs and mental health initiatives to promote students' resilience.
学生的心理健康越来越受到关注。新冠肺炎大流行带来了学术和非学术挑战,导致学生倦怠、焦虑和同理心下降。目的本研究旨在评估曲康健康学院学生的职业倦怠,探讨职业倦怠与焦虑、职业倦怠与共情的关系,并探讨学生的应对策略。方法采用收敛混合方法设计:(1)使用经过验证的仪器进行横断面调查。用Maslach倦怠量表(MBI-GS)测量倦怠,用广泛性焦虑障碍7项量表(GAD-7)测量焦虑,用人际反应指数(IRI)测量共情;(2)焦点小组,深入了解学生的经历和应对策略。调查采用描述性和多元统计分析,焦点群体采用演绎主题分析,遵循应对储备模型。结果21.45%的学生回应了调查。倦怠按量表进行报告。MBI-Exhaustion (MBI-EX)量表(mean= 4.07, SD= 1.56)、mbi -犬儒主义(MBI-CY)量表(mean= 2.63, SD= 1.53)、mbi -职业效能(MBI-PE)量表(mean= 3.97, SD= 1.22)。MBI-EX和MBI-CY与GAD-7评分相关。MBI-EX和MBI-CY与iri -共情关怀(IRI-EC)和iri -个人困扰(IRI-PD)相关,而MBI-PE与iri -透视谈话(IRI-PT)和IRI-EC相关。学生们使用了许多应对策略来建立弹性。结论2020年春季学期,曲康学生出现了职业倦怠。许多倦怠的原因和应对策略被确定。建议瞿启动师徒计划和心理健康倡议,以促进学生的弹性。
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引用次数: 1
Depression-anxiety in Adult Population of Qatar during the First Year of COVID-19 COVID-19第一年卡塔尔成年人群的抑郁焦虑
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0177
S. Khaled, I. Amro, L. Bader, T. Bellaj, Yousri Marzouki, Y. Hasan, Ibrahim Al-Kaabi, P. Woodruff, Majid Alabdulla, P. Haddad
There is limited data from Arabic-speaking countries on risk factors for depression and anxiety during the COVID-19 pandemic. Country-specific data is necessary given differences in culture, demographics, and COVID-19 infection and mortality rates. This study intended to identify the factors associated with symptoms of depression-anxiety in the adult population of Qatar during the first year of the COVID-19 pandemic. We conducted a cross-sectional online survey in Qatar between July and December 2020 after Qatar’s first COVID-19 wave and before the beginning of the second wave. Depression-anxiety was defined as a cut-off of 20 or higher on the PHQ-ADS scale. Of 1138 participants, 71.05% were female, 69.0% Arabs, and 70.0% Non-Qataris. 77 % were < 40 years (the median age in Qatar is 32 years). In a fully-adjusted model, six variables were significantly associated with PHQ-ADS; Arab ethnicity (OR=1.67, p=0.026), never married (OR=1.69, p < 0.015), prior psychiatric history (OR=1.80, p=0.009), Social Media induced worries (OR=1.72, p=0.003), history of COVID-19 (OR=1.76, p=0.039), loneliness (OR=1.91, p < 0.001), and lower levels of religiosity (OR=0.96, p=0.039). The potential risk factors identified may assist with anxiety and depression prevention in future COVID-19 waves, similar national events and assist with early intervention to treat sufferers.
在2019冠状病毒病大流行期间,阿拉伯语国家关于抑郁和焦虑风险因素的数据有限。鉴于文化、人口统计以及COVID-19感染和死亡率的差异,有必要提供针对具体国家的数据。本研究旨在确定在COVID-19大流行的第一年卡塔尔成年人群中与抑郁焦虑症状相关的因素。2020年7月至12月,在卡塔尔第一波COVID-19爆发后和第二波爆发前,我们在卡塔尔进行了一项横断面在线调查。抑郁焦虑被定义为PHQ-ADS量表中20或更高的分界点。在1138名参与者中,71.05%为女性,69.0%为阿拉伯人,70.0%为非卡塔尔人。77% < 40岁(卡塔尔的中位年龄为32岁)。在完全调整模型中,6个变量与PHQ-ADS显著相关;阿拉伯民族(OR=1.67, p=0.026)、未婚(OR=1.69, p < 0.015)、既往精神病史(OR=1.80, p=0.009)、社交媒体引发的担忧(OR=1.72, p=0.003)、COVID-19病史(OR=1.76, p=0.039)、孤独感(OR=1.91, p < 0.001)和较低的宗教信仰水平(OR=0.96, p=0.039)。确定的潜在风险因素可能有助于在未来的COVID-19浪潮中预防焦虑和抑郁,并有助于对患者进行早期干预。
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引用次数: 0
Depression in patients with spinal injury in Qatar: a mixed-methods study 卡塔尔脊髓损伤患者的抑郁症:一项混合方法研究
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0107
B. Al Shamari, L. OHara
Background: There is a high prevalence of depression in people with spinal injury. It has a major negative influence on health and performance of daily living activities following the injury. Social support plays an important role in the recovery process of patients. Objectives: The objectives of the study were to determine the prevalence of depression; identify the association between the level of depression and the cause and site of spinal injury, sociodemographic factors, and social support; and explore the experiences of depression in patients with spinal injury in Qatar. Methods: A cross-sectional mixed-methods study was conducted. All patients admitted to Hamad Medical Corporation in 2020 with spinal injury were surveyed using an interviewer-administered questionnaire in Arabic, English or Hindi. Depression was assessed using the Patient Health Questionnaire-9 (PHQ-9). The Social Support Survey was used to assess overall social support and four specific aspects of social support. Demographic data were collected. The cause and site of injury were obtained from patient records. Semi-structured interviews were conducted with purposively selected participants. Results: A total of 106 participants participated in the survey. In-depth interviews were conducted with 12 participants. For the survey component, the average age of participants was 35.82±10.00 years, the majority were males (94.3%), and 69% had some level of depression (mild: 28%, minimal: 25.5%, and moderate to severe: 15%). Depression was not associated with socio-demographic factors or the cause or site of spinal injury. Emotional/informational support and positive social interaction were inversely correlated with depression scores. The interviews revealed that spinal injury had a negative impact on participants’ daily lives and their physical, mental, social, and spiritual wellbeing. Emotional/informational support and positive social interaction were both inversely correlated with depression. This was consistent with the findings of the interviews, which highlighted the important role of social support in improving participants’ ability to cope with their new situation. Conclusion: Depression is prevalent among patients with spinal injury. Early detection, referral, and treatment of depression are recommended. Strategies to enhance emotional/informational support and positive social interaction should be developed and tested in patients with spinal injury.
背景:脊髓损伤患者抑郁发生率高。它对受伤后的健康和日常生活活动的表现有重大的负面影响。社会支持在患者康复过程中起着重要的作用。目的:本研究的目的是确定抑郁症的患病率;确定抑郁程度与脊髓损伤的原因和部位、社会人口因素和社会支持之间的关系;探讨卡塔尔脊髓损伤患者的抑郁经历。方法:采用横断面混合方法进行研究。2020年哈马德医疗公司收治的所有脊髓损伤患者都使用访谈者填写的阿拉伯语、英语或印地语问卷进行了调查。使用患者健康问卷-9 (PHQ-9)评估抑郁症。社会支持调查是用来评估整体社会支持和社会支持的四个具体方面。收集了人口统计数据。损伤的原因和部位从患者记录中获得。有目的地选择参与者进行半结构化访谈。结果:共有106人参与调查。对12名参与者进行了深度访谈。在调查部分,参与者的平均年龄为35.82±10.00岁,男性占94.3%,69%有不同程度的抑郁(轻度:28%,轻度:25.5%,中重度:15%)。抑郁症与社会人口因素或脊髓损伤的原因或部位无关。情绪/信息支持和积极的社会互动与抑郁得分呈负相关。访谈显示,脊髓损伤对参与者的日常生活以及他们的身体、心理、社会和精神健康都有负面影响。情绪/信息支持和积极的社会互动均与抑郁呈负相关。这与访谈的结果一致,访谈强调了社会支持在提高参与者应对新情况的能力方面的重要作用。结论:抑郁症在脊髓损伤患者中普遍存在。建议早期发现、转诊和治疗抑郁症。应该在脊髓损伤患者中开发和测试增强情感/信息支持和积极社会互动的策略。
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引用次数: 0
Modelling and Analysis of Power Electronic Converters for EV Charging/Discharging for G2V, V2G and V2X Operations G2V、V2G和V2X电动汽车充放电电力电子转换器建模与分析
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0014
A. Iqbal, S. Islam, M. Meraj
The research work deals with the implementation of various chargers used for electric vehicles in the context of Qatar. These chargers are categorized as slow, fast, and super-fast chargers. The electric vehicles not only lead to a reduction in carbon footprint, but the V2X mode of operation of EVs implemented with the help of a bidirectional converter is used to provide ancillary services in the system such as shaving peak and valley in load demand, frequency, and voltage regulation, balance the supply and demand for active power and reactive power, compensate grid current harmonics, improve power quality, provide reactive power compensation and improve system stability. Due to the above-mentioned advantages, V2X mode of operation will be explored in this research work.
该研究工作涉及在卡塔尔的背景下用于电动汽车的各种充电器的实施。这些充电器分为慢速、快速和超高速充电器。电动汽车不仅减少了碳足迹,而且借助双向变换器实现电动汽车的V2X运行模式,可在系统中提供辅助服务,如负载需求的调峰谷、频率和电压调节、有功和无功供需平衡、电网电流谐波补偿、改善电能质量、提供无功补偿和提高系统稳定性。鉴于上述优势,本研究工作将探索V2X的运行模式。
{"title":"Modelling and Analysis of Power Electronic Converters for EV Charging/Discharging for G2V, V2G and V2X Operations","authors":"A. Iqbal, S. Islam, M. Meraj","doi":"10.29117/quarfe.2021.0014","DOIUrl":"https://doi.org/10.29117/quarfe.2021.0014","url":null,"abstract":"The research work deals with the implementation of various chargers used for electric vehicles in the context of Qatar. These chargers are categorized as slow, fast, and super-fast chargers. The electric vehicles not only lead to a reduction in carbon footprint, but the V2X mode of operation of EVs implemented with the help of a bidirectional converter is used to provide ancillary services in the system such as shaving peak and valley in load demand, frequency, and voltage regulation, balance the supply and demand for active power and reactive power, compensate grid current harmonics, improve power quality, provide reactive power compensation and improve system stability. Due to the above-mentioned advantages, V2X mode of operation will be explored in this research work.","PeriodicalId":9295,"journal":{"name":"Building Resilience at Universities: Role of Innovation and Entrepreneurship","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80911195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecotoxicological assessment of two surfactant on the emryonic development 两种表面活性剂对胚胎发育的生态毒理学评价
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0149
Aldana Al-dosari, N. Younes, G. Nasrallah
In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 and Ploy-Q-47. as both surfactants are considered eco-friendly corrosion inhibitors. The calculated LC50 of Silicon-Q-22 and Poly-Q-47 was 22.36 and 8.28 mg/L, respectively. At NOEC both surfactants had resulted in teratogenic defects and cardiotoxicity, but only poly Q-47 resulted in neurotoxicity.
本研究以斑马鱼(Danio rerio)胚胎作为海洋动物模型,以确定硅酮- q -22和poly - q -47是否有可能引起器官特异性毒性(神经肌肉毒性、肝脏毒性、细胞毒性和心脏毒性)。由于这两种表面活性剂都被认为是环保型的缓蚀剂。Silicon-Q-22和Poly-Q-47的LC50分别为22.36和8.28 mg/L。在NOEC试验中,两种表面活性剂均导致致畸缺陷和心脏毒性,但只有聚Q-47导致神经毒性。
{"title":"Ecotoxicological assessment of two surfactant on the emryonic development","authors":"Aldana Al-dosari, N. Younes, G. Nasrallah","doi":"10.29117/quarfe.2021.0149","DOIUrl":"https://doi.org/10.29117/quarfe.2021.0149","url":null,"abstract":"In this study, zebrafish (Danio rerio) embryos was served as a model for marine fauna to determine if there is any potential of organ-specific toxicity (neuromuscular, hepatic, cytotoxic, and cardiac) caused by Silicone-Q-22 and Ploy-Q-47. as both surfactants are considered eco-friendly corrosion inhibitors. The calculated LC50 of Silicon-Q-22 and Poly-Q-47 was 22.36 and 8.28 mg/L, respectively. At NOEC both surfactants had resulted in teratogenic defects and cardiotoxicity, but only poly Q-47 resulted in neurotoxicity.","PeriodicalId":9295,"journal":{"name":"Building Resilience at Universities: Role of Innovation and Entrepreneurship","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79887237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Burnout and Resilience in Community Pharmacists in Qatar during the COVID-19 Pandemic: a Cross Sectional Study COVID-19大流行期间卡塔尔社区药剂师的职业倦怠和恢复力:一项横断面研究
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0134
Zeana Samir Alkudsi, Nadin Hany Kamel, A. El-Awaisi, Mujahed Shraim, M. ElHajj
Objective: The main aim of this study is to illustrate the prevalence of burnout and resilience among community pharmacists in Qatar during the COVID-19 pandemic. Methods: This is a cross-sectional study design that included the collection and analysis of quantitative data from community pharmacists in Qatar using a cross-sectional survey. Results: Overall, participants had a moderate level of burnout as illustrated in the mean scores of the three dimensions; 22.11±13.053 for emotional exhaustion, 7.17±6.55 for depersonalization, and 35.94±11.47 for personal accomplishment. The findings demonstrated that 15.2%, 15.6%, and 5.4% of community pharmacists had moderate levels of depression, anxiety, and stress, respectively. Further, they showed high resilience (35.7±8.57). Mental health outcomes were statistically positively correlated with fear while age was negatively correlated with depersonalization. Conclusion: This study is the first study to report the prevalence of mental health outcomes among community pharmacists during COVID-19 in Qatar. The pharmacists experienced moderate burnout but high resilience which indicates their high potential to overcome difficulties. Future interventions at the personal, national and organizational levels are needed to improve mental health during this pandemic by preventing and managing stress, improving self-efficacy and resilience, and providing adequate social support.
目的:本研究的主要目的是说明COVID-19大流行期间卡塔尔社区药剂师的职业倦怠和恢复力的流行情况。方法:这是一项横断面研究设计,包括收集和分析卡塔尔社区药剂师使用横断面调查的定量数据。结果:总体而言,被试在三个维度的平均得分中表现出中等程度的倦怠;情绪衰竭22.11±13.053分,人格解体7.17±6.55分,个人成就感35.94±11.47分。结果显示,15.2%、15.6%和5.4%的社区药师存在中度抑郁、焦虑和压力。此外,他们表现出较高的弹性(35.7±8.57)。心理健康结果与恐惧呈正相关,而年龄与人格解体呈负相关。结论:本研究是第一项报告卡塔尔社区药剂师在COVID-19期间心理健康结果患病率的研究。药师的职业倦怠程度适中,但心理弹性较高,具有较强的克服困难的潜力。今后需要在个人、国家和组织各级采取干预措施,通过预防和管理压力、提高自我效能和复原力以及提供充分的社会支持来改善这次大流行期间的心理健康。
{"title":"Burnout and Resilience in Community Pharmacists in Qatar during the COVID-19 Pandemic: a Cross Sectional Study","authors":"Zeana Samir Alkudsi, Nadin Hany Kamel, A. El-Awaisi, Mujahed Shraim, M. ElHajj","doi":"10.29117/quarfe.2021.0134","DOIUrl":"https://doi.org/10.29117/quarfe.2021.0134","url":null,"abstract":"Objective: The main aim of this study is to illustrate the prevalence of burnout and resilience among community pharmacists in Qatar during the COVID-19 pandemic. Methods: This is a cross-sectional study design that included the collection and analysis of quantitative data from community pharmacists in Qatar using a cross-sectional survey. Results: Overall, participants had a moderate level of burnout as illustrated in the mean scores of the three dimensions; 22.11±13.053 for emotional exhaustion, 7.17±6.55 for depersonalization, and 35.94±11.47 for personal accomplishment. The findings demonstrated that 15.2%, 15.6%, and 5.4% of community pharmacists had moderate levels of depression, anxiety, and stress, respectively. Further, they showed high resilience (35.7±8.57). Mental health outcomes were statistically positively correlated with fear while age was negatively correlated with depersonalization. Conclusion: This study is the first study to report the prevalence of mental health outcomes among community pharmacists during COVID-19 in Qatar. The pharmacists experienced moderate burnout but high resilience which indicates their high potential to overcome difficulties. Future interventions at the personal, national and organizational levels are needed to improve mental health during this pandemic by preventing and managing stress, improving self-efficacy and resilience, and providing adequate social support.","PeriodicalId":9295,"journal":{"name":"Building Resilience at Universities: Role of Innovation and Entrepreneurship","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76953233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Myosin Binding Protein-C in Sprague Dawley (SD) Rats exposed to Sub-Chronic oral dose of Cadmium Chloride 亚慢性口服氯化镉对SD大鼠心肌肌球蛋白结合蛋白c的影响
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0075
Enjoud Khalifa Al-Borshaid, Kavitha Varadharajan, Muralitharan Shanmugakonar, H. Al-Naemi
Cadmium is one of the major environmental pollutants associated with an increment in industrial and urbanization activities. It has health consequences when it reaches the human diet through the soil, water, and plant. Chronic exposure to cadmium has a serious effect on human health. It accumulates mainly in the liver and the kidney. In addition, it can accumulate in the different organs and tissues and exert its toxic effect on the body. Data generated from animal studies reported that elevated levels of cadmium in the blood lead to cardiovascular complications. Cardiac myosin-binding protein C (cMyBP-C) is associated with the myosin thick filament and is involved in cross-bridges cycling and regulation of muscle contraction. It is a reliable marker to indicate the status of cardiac contractility. Therefore, this study is carried out to investigate the effect of cadmium on levels of cMyBP-C during chronic cadmium toxicity. Male Sprague Dawley rats were subjected to a daily cadmium chloride dose (15ppm/Kg of body weight) for a period of 10 weeks. Then heart samples were collected and both gene and protein expression of cMyBP-C were analyzed. The data demonstrated that cadmium decreased cMyBP-C at the protein level and downregulated its expression at the gene level. Therefore, cMyBP-C can be used as a potential biomarker for cadmium cardiotoxicity
镉是与工业和城市化活动增加有关的主要环境污染物之一。当它通过土壤、水和植物进入人类饮食时,就会对健康产生影响。长期接触镉对人体健康有严重影响。它主要积聚在肝脏和肾脏。此外,它可以在不同的器官和组织中积累,对身体产生毒性作用。动物研究数据显示,血液中镉含量升高会导致心血管并发症。心肌肌球蛋白结合蛋白C (cMyBP-C)与肌球蛋白粗丝相关,参与过桥循环和肌肉收缩调节。它是指示心脏收缩状态的可靠标志。因此,本研究旨在探讨慢性镉中毒过程中镉对cMyBP-C水平的影响。雄性斯普拉格道利大鼠每天接受氯化镉剂量(15ppm/Kg体重),为期10周。然后采集心脏样本,分析cMyBP-C基因和蛋白表达。结果表明,镉在蛋白质水平上降低了cMyBP-C的表达,在基因水平上下调了cMyBP-C的表达。因此,cMyBP-C可以作为镉心脏毒性的潜在生物标志物
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引用次数: 0
An Examination of the Employment Preparedness, Job Satisfaction, and Impact in the Workplace of Qatar University Pharmacy Alumni: A Mixed Methods Study 卡塔尔大学药学院校友的就业准备、工作满意度和工作场所影响:一项混合方法研究
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0132
Mounyah Waiel Al-Nuaimi, Ranin Abidi, B. Mukhalalati, A. El-Awaisi, A. Awaisu, Mohhamed Diab, F. Mraiche
Introduction: The level of alumni’s job satisfaction and preparedness has been found to affect the impact in the workplace. Little is known about alumni’s employment experience in Qatar. Objective: The aim of this study is to explore the employment preparedness, job satisfaction and impact in the workplace of College of pharmacy graduates in Qatar. Methods: A sequential exploratory mixed methods study was conducted. For the qualitative phase, data were collected by focus groups and were analyzed thematically. Quantitative data collection involved administration of a validated questionnaire. Results: Research findings suggested that college of Pharmacy (CPH) alumni were mostly well prepared in terms of knowledge and skills. They were mostly satisfied about the curriculum and the experiential learning experience. The participants were challenged by the lack of deep knowledge and skills needed for their area of expertise. COVID-19 pandemic was associated with increased workload and stress. Being a Qatar University graduate facilitated the recruitment process. Lastly, a positive impact in the workplace was reported through implementation of NAPRA competencies and AFPC learning outcomes. Conclusion: This study will facilitate the understanding of factors that affect the preparedness, job satisfaction of CPH alumni and their impact in the workplace, which will ultimately enhance the learning experience in CPH.
引言:研究发现,校友的工作满意度和准备程度会影响其在工作场所的影响。校友们在卡塔尔的就业经历鲜为人知。目的:本研究旨在探讨卡塔尔药学院毕业生的就业准备、工作满意度及其对工作场所的影响。方法:采用顺序探索性混合方法进行研究。在定性阶段,通过焦点小组收集数据并进行主题分析。定量数据收集涉及有效问卷的管理。结果:研究结果表明,药学院毕业生在知识和技能方面的准备基本充分。他们大多对课程和体验式学习感到满意。与会者面临的挑战是缺乏其专业领域所需的深厚知识和技能。COVID-19大流行与工作量和压力增加有关。作为卡塔尔大学的毕业生,我的招聘过程非常顺利。最后,通过实施NAPRA能力和AFPC学习成果,报告了工作场所的积极影响。结论:本研究将有助于了解影响CPH校友准备、工作满意度及其对工作场所影响的因素,最终提升CPH的学习体验。
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引用次数: 0
Artificial Intelligence in Predicting Heart Failure 人工智能预测心力衰竭
Pub Date : 2021-10-20 DOI: 10.29117/quarfe.2021.0130
Rashid Ebrahim Al-Mannai, Mohammed Hamad Almerekhi, Mohammed Abdulla Al-Mannai, Mishahira N, K. K. Sadasivuni, H. Yalcin, H. Ouakad, I. Bahadur, S. Al-Maadeed, Asiya Albusaidi
Heart Failure is a major chronic disease that is increasing day by day and a great health burden in health care systems world wide. Artificial intelligence (AI) techniques such as machine learning (ML), deep learning (DL), and cognitive computer can play a critical role in the early detection and diagnosis of Heart Failure Detection, as well as outcome prediction and prognosis evaluation. The availability of large datasets from difference sources can be leveraged to build machine learning models that can empower clinicians by providing early warnings and insightful information on the underlying conditions of the patients
心力衰竭是一种日益增加的主要慢性疾病,是全世界卫生保健系统的一个重大健康负担。机器学习(ML)、深度学习(DL)、认知计算机等人工智能(AI)技术可以在心衰检测的早期发现和诊断,以及结局预测和预后评估中发挥关键作用。来自不同来源的大型数据集的可用性可以用来构建机器学习模型,通过提供早期预警和关于患者潜在状况的深刻信息,可以增强临床医生的能力
{"title":"Artificial Intelligence in Predicting Heart Failure","authors":"Rashid Ebrahim Al-Mannai, Mohammed Hamad Almerekhi, Mohammed Abdulla Al-Mannai, Mishahira N, K. K. Sadasivuni, H. Yalcin, H. Ouakad, I. Bahadur, S. Al-Maadeed, Asiya Albusaidi","doi":"10.29117/quarfe.2021.0130","DOIUrl":"https://doi.org/10.29117/quarfe.2021.0130","url":null,"abstract":"Heart Failure is a major chronic disease that is increasing day by day and a great health burden in health care systems world wide. Artificial intelligence (AI) techniques such as machine learning (ML), deep learning (DL), and cognitive computer can play a critical role in the early detection and diagnosis of Heart Failure Detection, as well as outcome prediction and prognosis evaluation. The availability of large datasets from difference sources can be leveraged to build machine learning models that can empower clinicians by providing early warnings and insightful information on the underlying conditions of the patients","PeriodicalId":9295,"journal":{"name":"Building Resilience at Universities: Role of Innovation and Entrepreneurship","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87514208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Building Resilience at Universities: Role of Innovation and Entrepreneurship
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