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Clinical characteristics vary between women and men in 67,524 patients with moderate obesity preoperative for laparoscopic adjustable gastric band (LAGB) 67,524例中度肥胖患者腹腔镜胃束带(LAGB)术前临床特征男女差异
Pub Date : 2020-08-21 DOI: 10.15406/AOWMC.2020.10.00316
Christopher Bashian, J. Schwartz, Luke Perry, G. Slotman
Background: As of 2018, LAGB represents <2% of weight loss operations, but with excellent long-term outcomes in selected patients. Thus, every clinical insight can help in selecting LAGB patients and planning surgery. While more women than men undergo bariatric surgery, differences between the sexes in obesity-related clinical conditions pre-operatively among patients seeking LAGB have not been investigated. The objective of this study was to identify variations in obesity-related co-morbidities among women and men who chose laparoscopic adjustable gastric band (LAGB). Methods: Pre-operative data on 53,292 women and 14,222 men undergoing LAGB were examined retrospectively from the Surgical Review Corporation’s Bariatric Outcomes Longitudinal Database (BOLD). Results: Women were more frequently African American and on Medicaid while men were more frequently Caucasian insured with Medicare. Men were older, heavier, and used alcohol, tobacco, and illicit substances more frequently. Men had higher rates of cardiovascular and pulmonary disease, diabetes, gout, impaired functional status, abdominal hernia, and liver disease. Women had higher rates of asthma, cholelithiasis, urinary incontinence, panniculitis, and mental health. Conclusion: Pre-operative characteristics of LAGB patients vary by sex. This clinical knowledge may aid physicians and surgeons in facilitating anticipatory management of patients with moderate obesity
背景:截至2018年,LAGB占减肥手术的比例<2%,但在选定的患者中具有良好的长期效果。因此,每一个临床见解都可以帮助选择LAGB患者和计划手术。虽然接受减肥手术的女性多于男性,但在寻求LAGB的患者中,术前肥胖相关临床状况的性别差异尚未得到调查。本研究的目的是确定选择腹腔镜可调节胃束带(LAGB)的女性和男性与肥胖相关的合并症的变化。方法:回顾性分析来自外科评论公司肥胖结果纵向数据库(BOLD)的53292名女性和14222名男性接受LAGB的术前数据。结果:女性更多的是非裔美国人和医疗补助,而男性更多的是白人医疗保险。男性年龄更大,体重更重,并且更频繁地使用酒精、烟草和非法物质。男性患心血管和肺部疾病、糖尿病、痛风、功能受损、腹疝和肝脏疾病的几率更高。女性患哮喘、胆石症、尿失禁、尿膜炎和心理健康的比例更高。结论:LAGB患者术前特征因性别而异。这些临床知识可以帮助内科医生和外科医生促进对中度肥胖患者的预期管理
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引用次数: 0
Pre-operative weight, BMI and the incidence of obesity co-morbidities vary by sex in bariatric surgery patients: analysis of 166,601 women and men with obesity 减肥手术患者术前体重、BMI和肥胖合并症的发生率因性别而异:对166601名肥胖患者的分析
Pub Date : 2020-08-08 DOI: 10.15406/AOWMC.2020.10.00315
C. Connors, Melissa L Gott, G. Slotman
Background: Variations in pre-operative characteristics by sex in bariatric surgery cannot be easily extrapolated from current literature. Objective: to identify pre-operative differences between males and females across the spectrum of bariatric procedures, weight and co-morbidities. Methods: Data from 166,601 pre-operative Surgical Review Corporation Bariatric Longitudinal Database (BOLD) patients undergoing bariatric surgery were divided into females (n=130,612) and males (n=35, 989). Statistics: Chi-square and Analysis of Variance (ANOVA). Results: Males displayed higher pre-operative age, BMI, weight, and rates of cardiopulmonary obesity co-morbidities, diabetes, gout, dyslipidemia, abdominal hernia, liver disease, alcohol, tobacco and substance abuse. Females suffered more from asthma, GERD, cholelithiasis, stress urinary incontinence, abdominal panniculitis, somatic obesity co-morbidities and mental health conditions (p<0.0001). Conclusions: Pre-operative weight, BMI, and weight-related medical problems vary by sex among patients undergoing bariatric surgery. With this advance knowledge, surgeons managing obese patients can anticipate co-morbidities by sex and adjust pre- and post- surgical preparations accordingly.
背景:从目前的文献中很难推断出减肥手术中术前特征的性别差异。目的:确定男性和女性在减肥手术、体重和合并症方面的术前差异。方法:数据来自166601例术前外科回顾公司减肥纵向数据库(BOLD)接受减肥手术的患者,分为女性(n=130,612)和男性(n= 35,989)。统计学:卡方和方差分析(ANOVA)。结果:男性术前年龄、BMI、体重、心肺肥胖合并症、糖尿病、痛风、血脂异常、腹疝、肝病、酒精、烟草和药物滥用的发生率更高。女性患哮喘、胃食管反流、胆石症、压力性尿失禁、腹膜炎、躯体肥胖合并症和精神健康状况的比例更高(p<0.0001)。结论:在接受减肥手术的患者中,术前体重、BMI和体重相关的医学问题因性别而异。有了这些先进的知识,外科医生可以根据性别预测肥胖患者的合并症,并相应地调整术前和术后的准备工作。
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引用次数: 0
Age categorization of overweight and obesity using waist circumference, waist height ratio and body mass index among children and youth in Nigeria 使用腰围、腰高比和身体质量指数对尼日利亚儿童和青少年超重和肥胖进行年龄分类
Pub Date : 2020-07-17 DOI: 10.15406/aowmc.2020.10.00314
F. Anumah, Rifkatu Mshelia-Reng, O. Omonua, R. Adelaiye, R. Shuaibu, Kenechukwu Odumodu, Kenneth C Onugha, Caleb O. Ehusani
Background: Undernutrition and obesity co-exist in Nigeria. The aim of this study was to evaluate the distribution of overweight and obesity across different age groups using waist circumference, waist height ratio and body mass index in Nigerian children. Methods: Cross-sectional study involving 2,893 students aged 9-18 years (1,140 boys and 1,753 girls) using multistage cluster sampling design. Weight, height, Waist circumference (WC) were measured, body mass index (BMI), waist to height ratio (WHtR) were calculated. Data analyzed to get mean, SD, Spearman correlation coefficients were computed to examine the association between WC, WHtRandBMI. Result : The mean BMI, WC and WHtR were statistically significantly higher in girls than in boys. Using WC, 107 (6.1%) of the girls and 44(3.9%) of the boys, had abdominal obesity. Increased WHtR occurred in 11.5% of the girls and 8.0% of the boys respectively. Using BMI,32.9% of the youths were either overweight (OW) or obese (OB): 28.8% in boys and 35.5% in girls. 371 (21.2%) and 252 (14.4%) of the girls were OW and OB, while 191 (16.8%) and 137 (12.0%) of the boys had OW and OB. There was a progressive increase in the WC and BMI across the age groups. A strong positive correlation coefficient was noted between WC and BMI 0.77842, between WHtR and BMI 0.73281, and between WC and WHtR 0.82197 p< 0.0001. Conclusion : The prevalence of overweight and obesity in Nigerian children is increasing, higher in girls than in boys. We recommend that in addition to BMI, WC or WHtR should be used to assess central adiposity in children.
背景:营养不良和肥胖在尼日利亚共存。本研究的目的是利用尼日利亚儿童的腰围、腰高比和身体质量指数来评估超重和肥胖在不同年龄组的分布。方法:采用多阶段整群抽样设计,对2893名9-18岁学生(男生1140名,女生1753名)进行横断面研究。测量体重、身高、腰围(WC),计算体重指数(BMI)、腰高比(WHtR)。对数据进行分析,计算平均值、标准差、Spearman相关系数,以检验WC、WHtRandBMI之间的相关性。结果:女孩的BMI、WC、WHtR均高于男孩,差异有统计学意义。使用WC, 107名女孩(6.1%)和44名男孩(3.9%)患有腹部肥胖。11.5%的女生和8.0%的男生WHtR增加。使用BMI,32.9%的青少年超重(OW)或肥胖(OB):男孩28.8%,女孩35.5%。女孩中OW和OB分别为371例(21.2%)和252例(14.4%),男孩中OW和OB分别为191例(16.8%)和137例(12.0%)。各年龄组的WC和BMI呈渐进式增加。腰围与体重指数为0.77842,腰围与体重指数为0.73281,腰围与体重指数为0.82197,p< 0.0001。结论:尼日利亚儿童超重和肥胖患病率呈上升趋势,女孩高于男孩。我们建议除BMI外,还应使用WC或WHtR来评估儿童中心性肥胖。
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引用次数: 0
The health and economic impacts of obesity 肥胖对健康和经济的影响
Pub Date : 2020-07-14 DOI: 10.15406/aowmc.2020.10.00313
Tahir Omer
The sharp rise in the prevalence of obesity in many countries have raised major global concern. Obesity is broadly preventable and has a complex multifactorial aetiology. The prevalence of obesity is on the rise and has increased by threefold since the mid 70s of last century. Obesity has overwhelming effect on individual’s health in terms of worsening morbidity and increased risk of mortality and on public health overall due to its economic burden on the health system. This narrative review utilises many published epidemiological studies that focus on the consequences of obesity in order to provide a framework for the overall cost of obesity in terms of its morbidity, mortality, and economic burden.
许多国家肥胖发病率的急剧上升引起了全球的关注。肥胖在很大程度上是可以预防的,它具有复杂的多因素病因。肥胖的流行率正在上升,自上世纪70年代中期以来已经增加了三倍。肥胖对个人健康产生了巨大的影响,发病率恶化,死亡风险增加,由于对卫生系统的经济负担,对整体公共卫生也产生了巨大的影响。这篇叙述性综述利用了许多已发表的流行病学研究,这些研究关注肥胖的后果,以便从发病率、死亡率和经济负担方面为肥胖的总体成本提供一个框架。
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引用次数: 3
The causes of obesity: an in-depth review 肥胖的原因:深入回顾
Pub Date : 2020-07-03 DOI: 10.15406/aowmc.2020.10.00312
Tahir Omer
Obesity is a medical condition defined as disproportionate fat storage in the body that might adversely affect health.1 The prevalence of obesity is drastically rising globally, and it is now considered a critical public health issue. According to the World Health Organisation WHO (2016), there are just under 2 billion overweight adults in the world. More than 600 million of them are considered obese. Around 40% of adults were overweight in 2016 and just under 15% were obese. The global prevalence of obesity has increased by threefold between 1975 and 2016. If the trend continues to rise, it is estimated that close to one third of the world adult population will be overweight and more than1 billion will be obese by 2025. Obesity is measured using body mass index (BMI) which is calculated by dividing the subject’s weight in kilograms by their square height in metres.1 A BMI of 30 or higher indicates obesity and although BMI is a very useful initial assessment method to diagnose obesity, it is not particularly accurate. It does not always reflect the degree of individual’s fat storage with great certainty. The WHO recognises this limitation and recommends its use as a screening tool only. Obesity infers a huge economic burden on the already outstretched health systems in many countries. The economic cost of obesity in England has been anticipated at being between £3.3–3.7 billion with an additional £3-3.7 billion related cost to treating overweight individuals.2
肥胖是一种医学病症,被定义为体内脂肪储存不成比例,可能对健康产生不利影响肥胖症的患病率在全球范围内急剧上升,现在被认为是一个重要的公共卫生问题。根据世界卫生组织(2016年)的数据,全球有不到20亿超重成年人。其中超过6亿人被认为是肥胖。2016年,大约40%的成年人超重,不到15%的成年人肥胖。1975年至2016年间,全球肥胖患病率增加了三倍。如果这一趋势继续上升,据估计,到2025年,世界上近三分之一的成年人将超重,超过10亿人将肥胖。肥胖是用身体质量指数(BMI)来衡量的,BMI是用受试者的体重(公斤)除以身高(米)的平方来计算的体重指数达到或超过30表明肥胖,虽然体重指数是诊断肥胖的一种非常有用的初步评估方法,但它并不是特别准确。它并不总是非常确定地反映个人脂肪储存的程度。世卫组织认识到这一局限性,并建议将其仅作为筛查工具使用。在许多国家,肥胖给已经不堪重负的卫生系统带来了巨大的经济负担。在英国,肥胖的经济成本预计在33 - 37亿英镑之间,治疗超重个体的额外成本为30 - 37亿英镑
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引用次数: 22
Risk factors associated with overweight and obesity among reproductive aged (15–49) years females in urban areas of Rajbiraj Municipality, Saptari 萨普塔里市拉吉比拉杰市城市地区育龄(15-49岁)女性超重和肥胖的相关危险因素
Pub Date : 2020-06-30 DOI: 10.15406/AOWMC.2020.10.00311
C. Shah, P. Jaisani, Madan Pandey, O. Sah, Mukundha Jha
Overweight and obesity has threatened the modern world not only in developed countries but equally in developing countries like Nepal. The study therefore aimed to assess the risk factors associated with overweight and obesity among reproductive aged women residing in Rajbiraj Municipality. A cross-sectional descriptive study was done on reproductive aged females (15-49 years) using a structured questionnaire. Weight, height, waist circumference and hip circumference were measured to determine indicators related to overweight and obesity. The anthropometric measurements were then analysed using WHO and IDF criteria. Microsoft excel 2007 and SPSS version 20 were used to analyze data. Chi square test was used to analyze the factors associated with BMI, WC and WHR cut-offs. The results showed a high prevalence of overweight and obesity in reproductive aged females residing in Rajbiraj. Hence, concerned agencies should launch appropriate programs to combat the factors.
超重和肥胖不仅在发达国家威胁着现代世界,在尼泊尔等发展中国家也同样如此。因此,该研究旨在评估居住在拉吉比拉市的育龄妇女中与超重和肥胖相关的危险因素。采用结构化问卷对育龄女性(15-49岁)进行横断面描述性研究。测量体重、身高、腰围和臀围,以确定与超重和肥胖有关的指标。然后使用WHO和IDF标准分析人体测量值。采用Microsoft excel 2007和SPSS version 20对数据进行分析。采用卡方检验分析BMI、WC和WHR截止值的相关因素。结果显示,居住在Rajbiraj的育龄妇女中超重和肥胖的患病率很高。因此,有关机构应该推出适当的计划来对抗这些因素。
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引用次数: 1
Risk factors associated with overweight and obesity among reproductive aged females residing in Bharatpur Metropolitan City 居住在巴拉特普尔大都会市的育龄妇女超重和肥胖的相关危险因素
Pub Date : 2020-06-25 DOI: 10.15406/AOWMC.2020.10.00310
Sadikshya Subedi, Richa Bhattarai, Rojina Bista
Overweight and obesity is becoming one of the major public health problems in developing countries like Nepal. A cross sectional study was conducted to assess the risk factors associated with overweight and obesity among reproductive aged females of 15-49 years residing in Bharatpur metropolitan city. Anthropometric measurement was used to determine Body Mass Index (BMI), Waist Circumference (WC) and Waist Hip Ratio (WHR). Data on socio-demographic, physical activity, dietary and behavioral factors was collected using structured questionnaire. Microsoft excel and SPSS version 20 were used to analyze data and chi square test was performed to analyze the factors associated with BMI, WC and WHR cut-offs. The result of this study revealed that 32.3% of females were overweight and 9.7% of females were obese. Similarly, on the basis of waist circumference 69% of females were abdominally obese and on the basis of waist hip ratio 68% of females were abdominally obese. Mean BMI was found to be 24.1c10.01 kg/m2, waist circumference was found to be 86.41±13.091 cm and waist hip ratio was found to be 0.89±0.108. This study shows that age, marital status, parity, stress, sleeping time, calorie intake, carbohydrate intake, physical activity and fruits consumption were found to be significantly associated (P<0.05) with overweight and obesity. Age, marital status, parity, calorie intake, fat intake, physical activity and fruits consumption were found to have significant association (P<0.05) with waist circumference. Similarly, age, marital status, parity, cloth wear, calorie intake, carbohydrate intake and physical activity were found to be significant predictors (P<0.05) of WHR in the study. The findings show a clear evidence of the rising trends of overweight and obesity among reproductive aged female. Overall this study indicate that efforts should be made to address the problem of overweight and obesity, by addressing the factors associated and minimize its consequences
超重和肥胖正在成为尼泊尔等发展中国家的主要公共卫生问题之一。通过横断面研究,对居住在印度巴拉特普尔市15-49岁育龄女性超重和肥胖的相关危险因素进行了评估。采用人体测量法测定身体质量指数(BMI)、腰围(WC)和腰臀比(WHR)。采用结构化问卷法收集社会人口统计、体育活动、饮食和行为等因素的数据。采用Microsoft excel和SPSS version 20对数据进行分析,采用卡方检验分析BMI、WC和WHR截止值的相关因素。研究结果显示,32.3%的女性超重,9.7%的女性肥胖。同样,根据腰围,69%的女性为腹部肥胖,根据腰臀比,68%的女性为腹部肥胖。平均BMI为24.1c10.01 kg/m2,腰围为86.41±13.091 cm,腰臀比为0.89±0.108。本研究发现,年龄、婚姻状况、胎次、压力、睡眠时间、卡路里摄入量、碳水化合物摄入量、体力活动和水果摄入量与超重和肥胖显著相关(P<0.05)。年龄、婚姻状况、胎次、卡路里摄入量、脂肪摄入量、体力活动和水果摄入量与腰围有显著相关(P<0.05)。同样,年龄、婚姻状况、胎次、衣服穿著、热量摄入、碳水化合物摄入和体力活动是WHR的显著预测因子(P<0.05)。研究结果清楚地表明,育龄女性中超重和肥胖的趋势正在上升。总的来说,这项研究表明,应该努力解决超重和肥胖的问题,通过解决相关因素,并尽量减少其后果
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引用次数: 0
Applications of the fourth-generation multi-theory model (MTM) of health behavior change toobesogenic behaviors in college students 第四代健康行为改变多理论模型(MTM)在大学生致生行为中的应用
Pub Date : 2020-06-23 DOI: 10.15406/AOWMC.2020.10.00308
M. Sharma
Obesity is a public health crisis that has reached pandemic proportions. It has multifactorial etiology and multiple negative physical and psychological consequences. Controlling the problem by altering obesogenic behaviors among college students is especially important because there is growing prevalence in this subgroup, there are long term effects for this subgroup, they are in formative years for obesogenic behaviors, and these behaviors are widely prevalent in this subgroup. The multi-theory model (MTM) of health behavior change is a new fourth-generation behavioral theory that has been applied to study obesogenic behaviors among college students. The purpose of this review was to examine the robustness and utility of MTM in designing efficacious and effective interventions to address obesogenic behaviors among US college students. A total of five studies published in MEDLINE, CINAHL, or ERIC met the inclusion criteria.The mean adjusted R2 for the initiation model based on the five studies was 0.38 (s.d. 0.15) and the mean adjusted R2 for the sustenance model was 0.34 (s.d. 0.14). The construct of behavioral confidence in the initiation model and the construct of emotional transformation in the sustenance model were significant in all five studies. MTM offers a feasible and practical framework for designing health promotion interventions for college students to address obesogenic behaviors
肥胖是一种公共卫生危机,已达到流行病的程度。它具有多因素的病因和多重负面的生理和心理后果。通过改变大学生的肥胖行为来控制这个问题尤为重要,因为这个亚群体的患病率越来越高,对这个亚群体有长期的影响,他们正处于肥胖行为的形成期,这些行为在这个亚群体中普遍存在。健康行为改变多理论模型(multi-theory model, MTM)是第四代新的行为学理论,已被应用于研究大学生致肥行为。本综述的目的是检验MTM在设计有效和有效的干预措施以解决美国大学生肥胖行为方面的稳健性和实用性。在MEDLINE、CINAHL或ERIC上发表的共5项研究符合纳入标准。基于5项研究的起始模型的平均校正R2为0.38(标准差0.15),维持模型的平均校正R2为0.34(标准差0.14)。五项研究中,行为自信的建构在起始模型中显著,情绪转化的建构在维持模型中显著。MTM为设计大学生健康促进干预措施解决肥胖行为提供了一个切实可行的框架
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引用次数: 0
The localization of HPV and CMV in the adipose tissues of female diabetic type 1 rats and the possibility of having a role of reactivity of COVID-19 in diabetic subjects as a new medical hypothesis 女性糖尿病1型大鼠脂肪组织中HPV和CMV的定位及在糖尿病患者中COVID-19反应性作用的可能性作为一种新的医学假设
Pub Date : 2020-06-23 DOI: 10.15406/AOWMC.2020.10.00309
Ahed J. Alkhatib
Introduction: Diabetes has various impacts on human body. It is thought that diabetes is predisposed by obesity. Obesity may due to several factors including genetically-environmental factors. The recent views that viruses may act as etiology for obesity. Study objectives: The main objectives of the present study were to investigate the possibility that CMV and HPV of having a role in initiating episodes of obesity and diabetes, and to test the hypothesis that co-existence of multi-viruses including corona virus may work synergistically to increase the impact of COVID-19 on diabetic patients. Methodology: In this study, a diabetic model was induced, the localization of HPV and CMV was determined using immunohistochemistry. Results: Study findings showed that both viruses HPV and CMV exist in the adipose tissue of diabetic rats. Both viruses were brown in color. Conclusions: Taken together, both CMV and HPV exist in the adipose tissue of diabetic rats, and this may explain the phenomenon of autoimmunity in diabetes from one side and from another side, we may explain the occurrence of synergistic effects of COVID-19 virus and the other viruses mentioned in this study.
糖尿病对人体的影响是多方面的。人们认为肥胖易导致糖尿病。肥胖可能是由多种因素造成的,包括遗传和环境因素。最近的观点认为病毒可能是肥胖的病因。研究目的:本研究的主要目的是调查巨细胞病毒和人乳头状瘤病毒在引发肥胖和糖尿病发作中的作用的可能性,并验证包括冠状病毒在内的多种病毒共存可能协同作用以增加COVID-19对糖尿病患者的影响的假设。方法:本研究建立糖尿病模型,采用免疫组化方法检测人乳头瘤病毒和巨细胞病毒的定位。结果:研究发现,在糖尿病大鼠的脂肪组织中存在HPV和CMV病毒。两种病毒都是棕色的。结论:综上所述,CMV和HPV都存在于糖尿病大鼠的脂肪组织中,这可能从一个侧面和另一个侧面解释了糖尿病的自身免疫现象,我们可能解释了COVID-19病毒与本研究中提到的其他病毒协同作用的发生。
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引用次数: 0
Obesity, COVID-19 and vitamin D: is there an association worth examining? 肥胖、COVID-19和维生素D:是否有值得研究的关联?
Pub Date : 2020-06-03 DOI: 10.15406/AOWMC.2020.10.00307
R. Marks
Many COVID-19 deaths among those enumerated in the context of the 2020 corona virus pandemic appear to be associated more often than not with obesity. At the same time, obesity has been linked to a deficiency in vitamin D, a factor that appears to hold some promise for advancing our ability to intervene in reducing COVID-19 severity. This mini-review reports on what the key literature is reporting in this regard, and offers some comments for clinicians and researchers. Drawn from PUBMED, data show that a positive impact on both obesity rates and COVID-19 morbidity and mortality rates may be attained by efforts to promote vitamin D sufficiency in vulnerable groups
在2020年冠状病毒大流行的背景下,许多COVID-19死亡病例似乎往往与肥胖有关。与此同时,肥胖与维生素D缺乏有关,这一因素似乎有望提高我们干预降低COVID-19严重程度的能力。这篇小型综述报告了在这方面的关键文献,并为临床医生和研究人员提供了一些评论。来自PUBMED的数据显示,通过努力促进弱势群体的维生素D充足,可能会对肥胖率和COVID-19发病率和死亡率产生积极影响
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引用次数: 0
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Advances in obesity, weight management & control
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