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Pseudo-Subdural Collection on Ultrasound: A Mirror Image Artefact 超声伪硬膜下采集的镜像艺术
Pub Date : 2022-10-05 DOI: 10.31579/2690-1919/270
Khalaf Saba
Teaching point: -Extra-calvarial subcutaneous or subgaleal collection can mimic as subdural collection on ultrasound due to mirror image artefacts.
教学点:-由于镜像伪影,颅外皮下或盔下采集在超声上可以模仿硬膜下采集。
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引用次数: 0
Epidemiological Aspects of the Management of Heart Failure Patients Seen in Cardiological Consultations in the National Hospital of Niamey 尼亚美国立医院心脏病科会诊中心衰患者管理的流行病学方面
Pub Date : 2022-10-05 DOI: 10.31579/2690-1919/266
H. Idrissa
Background/Aim: Heart failure is defined as a structural or functional abnormality of the heart resulting in an inability to supply the tissues with oxygen at a rate commensurate with their needs. Objective: To contribute to a better knowledge of the epidemiological aspects of the treatment of in charge of patient’s heart failure patients. Materials and Methods: This is a prospective, cross-sectional study conducted over a period of 6 months (February 2020 to October 2020 without April et May due to Covid) Result: Thus, our sample consisted of 300 cases. The average age was 56.9 +13.7 years with extremes ranging from 19 to 98 years. Housewives were the most represented at 43.7%. High blood pressure and sedentary lifestyle were the most common DRFs in 95% of the patients, followed by obesity in 22.3%. In 61.3% of the cases, patients knew they had heart disease but did not know the type. Unusual shortness of breath on exertion was the main sign that prompted patients to consult a doctor (67.7%). Only 2% weighed themselves regularly. All of our patients (99%) were aware of the recommendation for sodium restriction and more than half (58.3%) had adapted to a low-salt diet. Only 23.2% of our patients drank less than 1.5L per day. 29.7% of our patients were not physically active. Regarding treatment, diuretics were the most used as specific treatment in 64.3% of cases and antiplatelet agents in 12.3% of cases. Conclusion: Our study has highlighted educational gaps in the heart failure population. Further studies may help to initiate a therapeutic education approach for patients in order to improve their quality of life and Morbi-mortality.
背景/目的:心力衰竭被定义为心脏结构或功能异常,导致无法以与其需要相称的速度向组织提供氧气。目的:提高对心衰监护病人治疗的流行病学认识。材料和方法:这是一项为期6个月的前瞻性横断面研究(2020年2月至2020年10月,不包括因Covid而导致的4月和5月)结果:因此,我们的样本由300例组成。平均年龄为56.9岁+13.7岁,极端年龄为19岁~ 98岁。家庭主妇的比例最高,为43.7%。在95%的患者中,高血压和久坐的生活方式是最常见的drf,其次是肥胖(22.3%)。在61.3%的病例中,患者知道自己患有心脏病,但不知道其类型。异常呼吸短促是促使患者去看医生的主要症状(67.7%)。只有2%的人定期称体重。我们所有的患者(99%)都知道限制钠的建议,超过一半(58.3%)已经适应了低盐饮食。只有23.2%的患者每天饮酒量低于1.5升。29.7%的患者没有身体活动。在治疗方面,利尿剂作为特异性治疗最多,占64.3%,抗血小板药物占12.3%。结论:我们的研究突出了心力衰竭人群的教育差距。进一步的研究可能有助于对患者进行治疗性教育,以改善他们的生活质量和发病率-死亡率。
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引用次数: 0
Profile of Congenital Cardiopathies in Paediatric Departments A and B of the National Hospital Niamey National Hospital (Research article) 尼亚美国立医院A和B儿科先天性心脏病概况(研究文章)
Pub Date : 2022-10-05 DOI: 10.31579/2690-1919/267
H. Idrissa
Aim: The aim of this study was to determine the extent of congenital heart disease in the population of children, for a better management and prevention strategy. Materials and Methods: This was a descriptive and cross-sectional study over a period of 4 years 10 months from January 2016 to October 2020 (retrospective over 4 years and prospective over 10 months) at the National Hospital of Niamey; Were included in our study all patients aged 0 to 21 with congenital heart disease confirmed by cardiac ultrasound who were hospitalized or monitored externally. Our data were analyzed by Epi Info software in version 7.2.2.6. 24. Descriptive and analytical statistics were used: the mean with standard deviation (SD) (for normal distributive variations), odds ratio (OR) and the median (Me) for the description of asymmetric distributive values. The comparison of the proportions was also carried out; to do this we used the statistical test of chi2. The test is significant if p <0.05 Results: The gender ratio was 1.005 in favour of men. The median age of our patients was 16.8 months with extremes ranging from 0 months to 247 months, the most represented age group is 29 days to 24 months with 81.1%. The majority of our patients (62.4%) came from urban areas, parental consanguinity was present in 42.2% of cases. 55.3% of our patients had reported a notion of recurrent respiratory infection. Respiratory distress was found in 29.5% of cases, followed by fatigue during feedings (16.7%). Tachycardia was found in 72.2% of our patients, 49.6% were undernourished. Heart murmur was found in 80.3% of our patients, 4.4% had Down's syndrome. Cardiomegaly was found in 64.4% of our patients, 15.7% had pulmonary hypervascularization. CIV was found in 27.03% followed by T4F, CAV, and CIA with 20.39 respectively; 17.20 and 16.95%. Surgery was indicated in 68.3%. Anemia was found in 55% of our patients, 49.6% had hyperleukocytosis. Antibiotic treatment was started in 72.7% of cases, 31.2% had benefited from diuretics, 23.8% from iron supplementation, 10.3% was on beta blockers. 18.7% had received surgical treatment, PAH and endocarditis were found in 1 and 0.73% of cases, respectively. 34.1% were awaiting surgery. The recorded death rate was 27.3%. Conclusion: Congenital heart disease is becoming more and more frequent and constitutes a very important health problem in our pediatric departments. They are dominated by CIVs and T4s. The diagnosis and their management are still difficult due to the lack of diagnostic and therapeutic means.
目的:本研究的目的是确定儿童先天性心脏病的程度,以便制定更好的管理和预防策略。材料和方法:这是一项在尼亚美国家医院进行的为期4年10个月的描述性和横断面研究,从2016年1月到2020年10月(回顾性研究超过4年,前瞻性研究超过10个月);在我们的研究中,所有年龄在0至21岁的先天性心脏病患者都被纳入了心脏超声检查,并接受了住院或外部监测。我们的数据通过Epi Info软件7.2.2.6版进行了分析。24.使用描述性和分析统计学:标准差平均值(SD)(正态分布变异)、比值比(OR)和中位数(Me)用于描述不对称分布值。还对比例进行了比较;为此,我们使用了chi2的统计检验。如果p<0.05,则该测试具有显著性。结果:男性的性别比为1.005。我们的患者中位年龄为16.8个月,极端年龄从0个月到247个月,最具代表性的年龄组为29天到24个月,占81.1%。我们的大多数患者(62.4%)来自城市地区,42.2%的病例存在父母血缘关系。55.3%的患者报告有复发性呼吸道感染的概念。29.5%的患者出现呼吸窘迫,其次是进食时的疲劳(16.7%)。72.2%的患者出现心动过速,49.6%的患者营养不良。80.3%的患者出现心脏杂音,4.4%的患者出现唐氏综合征。64.4%的患者出现心脏肥大,15.7%的患者出现肺血管过多。CIV检出率为27.03%,其次是T4F、CAV和CIA,分别为20.39%;17.20%和16.95%。68.3%的患者需要手术。55%的患者出现贫血,49.6%的患者出现白细胞增多。72.7%的病例开始了抗生素治疗,31.2%的患者受益于利尿剂,23.8%的患者受益于铁补充剂,10.3%的患者受益於β受体阻滞剂。18.7%的患者接受过手术治疗,PAH和心内膜炎的发生率分别为1和0.73%。34.1%的患者正在等待手术。记录的死亡率为27.3%。结论:先天性心脏病越来越频繁,在我们的儿科构成了一个非常重要的健康问题。它们主要是CIV和T4。由于缺乏诊断和治疗手段,诊断和管理仍然很困难。
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引用次数: 0
An Overview of Oxytocin: Chemical Structure, Receptors, Physiological Functions, Measurement Techniques of oxytocin, and Metabolism 催产素综述:化学结构、受体、生理功能、催产素测定技术及代谢
Pub Date : 2022-10-05 DOI: 10.31579/2690-1919/256
Azab Elsayed Azab
Background: Oxytocin is a peptide hormone comprising 9 amino acids. It is produced in the hypothalamus and stored and secreted by the posterior lobe of the pituitary gland and synthesized in other organs such as the uterus, ovaries, placenta, heart, blood vessels, skin, kidneys, and testis. Receptors of oxytocin are present on myoepithelial cells, heart, blood vessels, macrophages, thymus, pancreas, kidneys, and adipocytes. Objectives: The current review aimed to give highlight the oxytocin structure, receptors, physiological functions, measurement techniques, and metabolism. Oxytocin is a small peptide that consists of nine amino acids in a six–amino acid ring formed by cysteine bonds and a three–amino acid tail with a terminal amine. It is synthesized in brain regions that are critical to behavioral and physiologic homeostasis. Oxytocin is involved in uterine contraction during labor and ejection of milk during breastfeeding and plays a role in social behavior, emotions love and affection, the period after childbirth, and metabolic functions. The action of oxytocin in facilitating human bonding and social relation is well known. The effects of Oxytocin on metabolism and food intake suggesting its potential effects in treating obesity. The half-life time of oxytocin in the brain is triple as long as its half-life time in the periphery. The sensitivity and density of oxytocin receptors increase during labor. After birth, the neonatal baby sucks on his mother's breast, causing the release of milk by stimulating hypothalamic neurons to produce oxytocin. Oxytocin neurons have been heavily implicated in mediating sexual behavior in both humans and animals. The social memory was enhanced by central oxytocin administration in male rats. The action of oxytocin affects social memory in multiple brain regions, including the ventral hippocampus, amygdala, olfactory bulb, and lateral septum. Oxytocin neurons may mediate MC4R-driven sexual behavior in male mice. MC4R signaling in oxytocin neurons permits ejaculation. A decreased latency to ejaculate in rabbits and rats after administration of oxytocin. The effect of oxytocin receptor ligands on the ejaculatory response may be due to the modulation of dopamine serotonin neurotransmission. Oxytocin lowers the threshold for the initiation of maternal behavior but is not involved in its maintenance. The oxytocin and the melanin-concentrating hormone (MCH) systems may interact to modulate maternal behavior. Oxytocin regulates maternal- or mating-regulated mood. Initial measurements of oxytocin by using radioimmunoassay and bioassays suggested that oxytocin concentration in blood is very low, 5 pg/ml, with small increases as pulses,15 pg/ml, during lactation and uterine contractions. Variations in oxytocin concentration, especially in rapid response to specific experiences, such as anticipation of breastfeeding, sexual stimulation, exercise, affiliative social contact, and psychologic stress. Oxytocin is rapidly r
背景:催产素是一种由9个氨基酸组成的肽类激素。它在下丘脑产生,由垂体后叶储存和分泌,并在子宫、卵巢、胎盘、心脏、血管、皮肤、肾脏和睾丸等其他器官合成。催产素受体存在于肌上皮细胞、心脏、血管、巨噬细胞、胸腺、胰腺、肾脏和脂肪细胞上。目的:本综述旨在重点介绍催产素的结构、受体、生理功能、测量技术和代谢。催产素是一种小肽,由半胱氨酸键形成的六个氨基酸环中的九个氨基酸和带有末端胺的三个氨基酸尾组成。它是在大脑中对行为和生理稳态至关重要的区域合成的。催产素参与分娩期间的子宫收缩和母乳喂养期间的排乳,并在社会行为、情感、爱和感情、分娩后的时期和代谢功能中发挥作用。催产素在促进人类联系和社会关系方面的作用是众所周知的。催产素对新陈代谢和食物摄入的影响表明其在治疗肥胖方面的潜在作用。催产素在大脑中的半衰期是其在外周半衰期的三倍。催产素受体的敏感性和密度在分娩过程中增加。出生后,新生儿吮吸母亲的乳房,通过刺激下丘脑神经元产生催产素来释放乳汁。催产素神经元在人类和动物的性行为中起着重要的中介作用。雄性大鼠通过中枢催产素给药增强了社交记忆。催产素的作用影响大脑多个区域的社交记忆,包括腹侧海马体、杏仁核、嗅球和侧隔。催产素神经元可能介导雄性小鼠MC4R驱动的性行为。催产素神经元中的MC4R信号允许射精。给予催产素后,兔子和大鼠的射精潜伏期降低。催产素受体配体对射精反应的影响可能是由于多巴胺血清素神经传递的调节。催产素降低了母体行为启动的阈值,但不参与其维持。催产素和黑色素浓缩激素(MCH)系统可能相互作用以调节母体行为。催产素调节母体或交配调节的情绪。使用放射免疫分析法和生物测定法对催产素进行的初步测量表明,在哺乳和宫缩期间,血液中的催产素浓度非常低,为5 pg/ml,随着脉冲的增加而略有增加,为15 pg/ml。催产素浓度的变化,尤其是对特定经历的快速反应,如对母乳喂养的预期、性刺激、锻炼、社交接触和心理压力。催产素通过肝脏和肾脏迅速从血浆中清除。催产素酶活性在整个妊娠期增加,并在血浆、胎盘和子宫中达到峰值。它也在乳腺、心脏、肾脏和小肠中表达。大脑、脾脏、肝脏、骨骼肌、睾丸和结肠的活动水平较低。催产素的血浆半衰期在1到6分钟之间。半衰期在妊娠晚期和哺乳期降低。结论:催产素是一种在脑区和其他器官合成的肽类激素,在许多器官中具有受体。它在社会行为、情感、爱和感情、产后时期和代谢功能中发挥作用。它在治疗肥胖方面的潜在作用。催产素在大脑中的半衰期是其在外周半衰期的三倍。催产素神经元可能介导MC4R驱动的性行为。催产素浓度的变化,尤其是对特定经历的快速反应。催产素通过肝脏和肾脏迅速从血浆中清除。催产素的血浆半衰期为1-6分钟。半衰期在妊娠晚期和哺乳期降低。
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引用次数: 0
Synthesis of Some Organic Ammonium Formate Salts and Study of Their Antifungal Properties 几种有机甲酸铵盐的合成及其抗菌性能研究
Pub Date : 2022-10-05 DOI: 10.31579/2690-1919/257
Ramadan Ali Bawa
This work is concerned with the preparation of a number of organic ammonium formate salts (or ionic liquids; ILs) throughout a reaction between the formic acid and some aliphatic and aromatic amines including the ammonia. Five organic ammonium formate salts were formed, some of them were in the form of solid salts and others were as the ionic liquids (ILs) at room temperature. The yields of the prepared organic salts ranged from (21%) to (79%). However, some attempts towards the preparation of other fifteen organic salts were not successful. The resulting five organic ammonium formate salts/ionic liquids were characterized using a number of spectroscopic techniques such as the infrared (IR), the nuclear magnetic resonance spectroscopy (1HNMR) and the mass spectrometry (ms). The collected spectroscopic data confirmed the formation of theses organic ammonium formate salts. The antifungal properties of the prepared organic ammonium formate salts were investigated against the aspergillus niger (A. niger), and the antifungal results were compared with the antifungal effect of the commercially available antifungal agent Daktarin, which was used as a reference in this study.
这项工作涉及在甲酸与包括氨在内的一些脂肪族和芳香族胺之间的整个反应过程中制备许多有机甲酸铵盐(或离子液体;离子液体)。在室温下形成了五种有机甲酸铵盐,其中一些是固体盐形式,另一些是离子液体形式。制备的有机盐的产率在(21%)至(79%)之间。然而,制备其他15种有机盐的一些尝试没有成功。使用红外(IR)、核磁共振波谱(1HNMR)和质谱(ms)等多种光谱技术对所得的五种有机甲酸铵盐/离子液体进行了表征。收集的光谱数据证实了这些有机甲酸铵盐的形成。研究了所制备的有机甲酸铵盐对黑曲霉(A.niger)的抗真菌性能,并将其抗真菌效果与本研究中可供参考的市售抗真菌剂Daktarin的抗真菌效果进行了比较。
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引用次数: 0
Oncology Information Systems: New Product Launches and Collaborations to Improve Quality of Care 肿瘤学信息系统:新产品发布和合作以提高护理质量
Pub Date : 2022-06-27 DOI: 10.31579/2690-1919/254
Ashish M. Gujrathi
The increase in prevalence of cancer, availability of different types of cancer treatments, and efficient management of treatment led to the development of oncology information systems. Clinics, healthcare organizations, and hospitals began utilization of oncology information systems for management of the entire treatment.
癌症患病率的增加、不同类型癌症治疗的可用性以及治疗的有效管理导致了肿瘤学信息系统的发展。诊所、医疗机构和医院开始使用肿瘤信息系统来管理整个治疗过程。
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引用次数: 0
Airway Foreign Bodies in Children: A Review Article 儿童气道异物:一篇综述
Pub Date : 2022-06-27 DOI: 10.31579/2690-1919/250
Volkan Sarper Erikci
Foreign body aspiration (FBA) in children represents a significant morbidity and even mortality producing sudden deaths. Regarded as a major public health issue, FBA may be the end result of aspiration of various organic and inorganic materials. Parental and public awareness including preventive measures is important in avoiding these injuries. The consequences of FBA may pose great challenge for both the children, their families together with clinicians dealing with these children. In this review article it is aimed to discuss the epidemiology, clinical presentations, diagnosis and treatment modalities of FBA in children under the light of relevant literature.
儿童异物吸入(FBA)发病率高,甚至死亡率高,导致猝死。FBA被认为是一个重大的公共卫生问题,可能是吸入各种有机和无机材料的最终结果。家长和公众的意识,包括预防措施,对于避免这些伤害很重要。FBA的后果可能会给孩子、他们的家庭以及治疗这些孩子的临床医生带来巨大的挑战。本文结合相关文献,就小儿FBA的流行病学、临床表现、诊断及治疗方法进行综述。
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引用次数: 0
Prevention of Smoking in Scholarship Students of the Faculty of Medical Sciences of Artemisa 阿尔忒弥斯医学院奖学金学生的吸烟预防
Pub Date : 2022-06-27 DOI: 10.31579/2690-1919/252
Jorge Félix Rodríguez Hernández
Introduction: Young people expose dissimilar reasons as justification for tobacco consumption. The presence of smoking in university students studying medicine and nursing becomes a challenge for institutional authorities, in their purpose of solving the health problem. Objective: to design an action plan for the prevention of smoking in scholarship students of the Faculty of Medical Sciences of Artemisa. Methods: a descriptive, prospective longitudinal study was developed with 211 smoking scholarship students from the aforementioned entity in the period from January 20 to March 25, 2020. Procedures were used such as: documentary review, observation, survey, focus group, brainstorming, and cause and effect diagram. Results: 22 causes were identified that favored the increase in smoking, six correspond to strategic and organizational gaps; seven are related to teachers; five correspond to the methodological teaching process and four are linked to educational work. Likewise, an action plan focused on seven objectives, 18 activities and four indicators was developed to evaluate the implementation process. Conclusions: The smoking prevention strategy applied to smoking scholarship students at the Faculty of Medical Sciences of Artemisa does not ensure the reduction of this toxic habit, which is potentially vulnerable with the proposed action plan.
引言:年轻人暴露出不同的理由作为吸烟的理由。在学习医学和护理的大学生中吸烟的存在对机构当局来说是一个挑战,因为他们的目的是解决健康问题。目的:制定阿尔忒弥斯医学院奖学金学生预防吸烟的行动计划。方法:在2020年1月20日至3月25日期间,对来自上述实体的211名吸烟奖学金学生进行了一项描述性前瞻性纵向研究。使用的程序包括:文献综述、观察、调查、焦点小组、头脑风暴和因果图。结果:确定了22个有利于吸烟增加的原因,其中6个与战略和组织差距相对应;七名与教师有关;五个与方法论教学过程相对应,四个与教育工作相关。同样,还制定了一项行动计划,重点是7项目标、18项活动和4项指标,以评估执行过程。结论:Artemisa医学科学院吸烟奖学金学生的吸烟预防策略并不能确保减少这种有毒习惯,根据拟议的行动计划,这种习惯可能很脆弱。
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引用次数: 0
In Vitro Antibacterial Effect of Essential Oil and Two Extracts of Myrtus Communis Leaves 桃金娘叶挥发油及两种提取物的体外抗菌作用
Pub Date : 2022-06-27 DOI: 10.31579/2690-1919/251
Rim M. Harfouch
Our study aims at evaluating the efficacy of extracts and essential oil of Myrtus communis leaves from the Syrian coast against several bacterial strains. The leaves were collected and dried, extracted for essential oil and ethanolic and hexan extracts were prepared. The yield of essential oil was measured and the chemical composition of the essential oil was determined using Gas Chromatography. The yield of essential oil was 1.3 ml/100 g, and the richest component was alpha-pinene. Our results showed that the ethanolic and hexan extracts of Myrtus communis had higher antibacterial activity against Gram positive bacteria (Staphylococcus aureus and Streptococcus pyogenes) than Gram negative bacteria (Escherichia coli and Pseudomonas aeruginosa). The ethanolic extract showed the greatest inhibitory effect against Staphylococcus aureus. These results demonstrate that Myrtus communis leaves extract has high antibacterial activity, making it a source of compounds to be used for the treatment of Gram-positive bacterial infections.
我们的研究旨在评估叙利亚海岸杨梅叶提取物和精油对几种细菌菌株的疗效。收集叶子并干燥,提取精油,制备乙醇和己烷提取物。用气相色谱法测定了精油的收率,并测定了精油中的化学成分。精油的产率为1.3ml/100g,并且最丰富的组分是α-蒎烯。结果表明,杨梅乙醇提取物和己烷提取物对革兰氏阳性菌(金黄色葡萄球菌和化脓性链球菌)的抗菌活性高于革兰氏阴性菌(大肠杆菌和铜绿假单胞菌)。乙醇提取物对金黄色葡萄球菌的抑制作用最强。这些结果表明,杨梅叶提取物具有很高的抗菌活性,使其成为用于治疗革兰氏阳性细菌感染的化合物的来源。
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引用次数: 0
Pediatric Caustic Ingestion: A Review Article 儿童腐蚀性摄入:一篇综述文章
Pub Date : 2022-05-07 DOI: 10.31579/2690-1919/248
V. Erikçi
Caustic ingestion injuries represent a significant morbidity and even mortality producing aerodigestive tract burns. Regarded as a major public health issue, caustic injuries may be produced by various chemicals including alkali and acid agents, phenols and oxidizing substances such as peroxides or chlorine bleaches. Public awareness including preventive measures is important in avoiding these injuries. The consequences of caustic ingestion may pose great challenge for both the patients, their families together with clinicians dealing with these children. In this review article it is aimed to discuss the clinical presentations, treatment modalities of these children under the light of relevant literature.
腐蚀性摄入损伤是导致空气消化道烧伤的重要发病率甚至死亡率。作为一个主要的公共卫生问题,各种化学物质可能会造成腐蚀性伤害,包括碱和酸剂、酚类和氧化物质,如过氧化物或氯漂白剂。包括预防措施在内的公众意识对于避免这些伤害非常重要。腐蚀性摄入的后果可能会对患者、他们的家人以及处理这些儿童的临床医生构成巨大挑战。在这篇综述文章中,旨在根据相关文献讨论这些儿童的临床表现、治疗方式。
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引用次数: 0
期刊
Journal of clinical research and reports
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