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An Overvıew of Lower Gastroıntestınal Bleedıng ın Infants and Toddlers: A Revıew Artıcle 低Gastroıntestınal Bleedıng ın的一个Overvıew婴幼儿:一个Revıew Artıcle
Pub Date : 2022-01-06 DOI: 10.31579/2690-1919/212
Volkan Sarper Erikci
Lower gastrointestinal bleeding (LGIB) in infants and toddlers is commonly encountered in clinical practice. There are several factors producing LGIB in these children and are usually managed with regard to the underlying pathology that produces LGIB. Although majority of these bleeding episodes is self limited, certain infants and toddlers with LGIB may necessitate prompt management including urgent surgical intervention. In this review article it is aimed to review the etiology, epidemiology, clinical manifestations and principles of treatment of LGIB in infants and toddlers under the light of relevant literature.
下消化道出血(LGIB)在婴幼儿的临床实践中是常见的。在这些儿童中产生LGIB有几个因素,通常是根据产生LGIB的潜在病理来处理的。虽然大多数出血发作是自限性的,但某些LGIB的婴幼儿可能需要及时处理,包括紧急手术干预。本文结合相关文献,对婴幼儿LGIB的病因、流行病学、临床表现及治疗原则进行综述。
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引用次数: 0
The Effective Management and Outcome of Hand Burns 手部烧伤的有效治疗与疗效
Pub Date : 2022-01-06 DOI: 10.31579/2690-1919/213
Subin Joseph
Burns is a common public health problem and these injuries can be accidental, suicidal or even homicidal in nature. Hands being the most active part of the body, are often involved in burns. Hand burns represent three percent of body surface area, and are involved in more than 80% of all severe burns. Hand burns predominantly affect young adults and therefore have serious social and financial implications. The hand is one of the most frequent sites of burns scar contracture deformity. The deformities and contractures result in lifelong physical problems and affects the normal functioning of the person.
烧伤是一种常见的公共卫生问题,这些伤害可能是意外的,自杀的,甚至是杀人的。手是身体最活跃的部位,经常被烧伤。手部烧伤占体表面积的3%,超过80%的严重烧伤与手部烧伤有关。手烧伤主要影响年轻人,因此具有严重的社会和经济影响。手部是烧伤瘢痕挛缩畸形最常见的部位之一。畸形和挛缩会导致终生的身体问题,并影响人的正常功能。
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引用次数: 0
Design, Simulation, Implementation and Measurement of Respiration Rate by Strain Gauge Sensor and Induction Method 应变传感器和感应法呼吸速率的设计、仿真、实现和测量
Pub Date : 2022-01-06 DOI: 10.31579/2690-1919/215
H. Shirzadfar, Sadaf Anbarzadeh, Samaneh Dohani
The human body has vital parameters such as respiration, heart rate, and body temperature. Respiratory rate (RR) is a parameter that expresses the rate of respiration per minute. Respiratory activities play an essential role in human life. The rate of respiration has a particular range, which is 14-18 cycles per minute for a healthy and normal person at rest. The oxygen in the blood enters the body during respiration and is expelled as carbon dioxide in return. Any problems with breathing may pose a serious health risk. An abnormal breathing pattern indicates serious illnesses such as cardiac arrest and hospitalization in the intensive care unit (ICU) and when it falls below a certain limit, it indicates a loss of consciousness. This is why it is so imperative to develop devices and methods measuring respiration rates.
人体有重要的参数,如呼吸、心率和体温。呼吸速率(RR)是表示每分钟呼吸速率的参数。呼吸活动在人类生活中起着至关重要的作用。呼吸速率有一个特定的范围,健康和正常的人在休息时的呼吸速率为每分钟14-18次。血液中的氧气在呼吸过程中进入人体,并以二氧化碳的形式排出体外。任何呼吸问题都可能对健康构成严重威胁。异常的呼吸模式预示着严重的疾病,如心脏骤停和重症监护病房(ICU)的住院治疗,当它低于一定的限度时,就预示着意识丧失。这就是为什么开发测量呼吸速率的设备和方法是如此必要。
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引用次数: 0
Lipid Profile an Important Risk Factor in Patients with Ovarian Tumors: A-Meta-Analysis 脂质谱是卵巢肿瘤患者的重要危险因素:meta分析
Pub Date : 2022-01-06 DOI: 10.31579/2690-1919/220
A. Clim, Lonel Nati, Flaviu Ionut Faur, A. Dobrescu
Introduction In the literature ovarian tumors are know to be one of the deadliest gynecological malignancies [1-4]. In US this type of malignancy represents 2.3 % of all cancer-related death and about 4 % of all new cancer cases among women. There are several studies that have reported the role of lipid profiles and it’s role in ovarian tumorigenesis. Fatty acids are essential for cancer cells progression[4-8]. In our study we investigated the true differance in circulating lipid profiles (total cholesterol TC, triglyceride TG, high-density lipoprotein cholesterol HDL, low density lipoprotein cholesterol LDL) among patients with and without ovarian tumors (OT) using a meta-analytical approach. Methods The meta-analysis was conducted using the MOOSE guidelines. PubMed, EMBASE and Cochrane Library were extensively searched (with a period of publication restriction between 2007 and 2019) to indentify published studies using the following keywords: “ total cholesterol ”, “high-density lipoprotein”, “ triglycerides ”, “ low-density lipoprotein ”, “ ovarian cancer”, “ ovarian tumor ”, “ lipid profile ”. The search methodology is shown in Fig. 1 and all references of retrieved articles were searched manually. Results Seven studies, involving 1542 OT cases and 2195 non-cases of OT were included in this meta-analysis and I² statistics ranged between 97 and 99%. Mean circulating TC and HDL were significantly lower among OT cases compared to non-OT cases (P<0.04 and P<0.005). Conclusion There is a modest significant association between circulating HDL and risk of ovarian tumor but it is crucial to elucidate the implications of HDL in tumor manifestations and growth.
在文献中,卵巢肿瘤被认为是最致命的妇科恶性肿瘤之一[1-4]。在美国,这种类型的恶性肿瘤占所有癌症相关死亡的2.3%,约占所有妇女癌症新病例的4%。有几项研究报道了脂质谱的作用以及它在卵巢肿瘤发生中的作用。脂肪酸是癌细胞进展所必需的[4-8]。在我们的研究中,我们使用荟萃分析方法调查了卵巢肿瘤(OT)患者和非OT患者循环脂质谱(总胆固醇TC、甘油三酯TG、高密度脂蛋白胆固醇HDL、低密度脂蛋白胆固醇LDL)的真正差异。方法采用MOOSE指南进行meta分析。广泛检索PubMed、EMBASE和Cochrane图书馆(2007年至2019年期间有发表限制),以确定使用以下关键词发表的研究:“总胆固醇”、“高密度脂蛋白”、“甘油三酯”、“低密度脂蛋白”、“卵巢癌”、“卵巢肿瘤”、“脂质谱”。检索方法如图1所示,所有检索文献均采用人工检索。结果本meta分析纳入7项研究,共1542例OT患者和2195例非OT患者,I²统计量在97% ~ 99%之间。与非OT组相比,OT组的平均循环TC和HDL显著降低(P<0.04和P<0.005)。结论循环HDL与卵巢肿瘤风险有一定的相关性,但阐明HDL在肿瘤表现和生长中的意义至关重要。
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引用次数: 0
Stasis Ulcers – The Unifying Concept 瘀疮——统一的概念
Pub Date : 2021-12-20 DOI: 10.31579/2690-1919/211
Jochanan E. Naschitz
Chronic stasis dermatitis, usually confined to the lower legs, is a complication of longstanding interstitial edema and inflammation, due either to venous hypertension or disorders having in common excessive lymph overload. Heart failure, renal failure, liver cirrhosis, secondary and primary diseases of lymph vessels may complicate with stasis dermatitis. The same mechanisms causing stasis dermatitis can also generate skin ulcers superimposed on stasis dermatitis. In the appropriate context such skin ulcers are called "venous ulcers" or, in different situations, “stasis ulcers”. The distinction between venous and other stasis ulcers is usually possible at the bedside. Also, some general measures of therapy are similar for venous and other stasis ulcers: such are elastic compression, topical skin care and ulcer care. In having in common the pathophysiological mechanisms, in bearing clinical resemblance, and responding to similar therapies, a unifying concept may be opportune to comprise the spectrum of stasis dermatitis, venous and other stasis ulcers. The present work is an appeal to this aim.
慢性淤滞性皮炎通常局限于小腿,是长期间质水肿和炎症的并发症,原因是静脉高压或常见的过度淋巴过载疾病。心力衰竭、肾功能衰竭、肝硬化、淋巴管的继发性和原发性疾病都可能并发淤滞性皮炎。引起停滞性皮炎的相同机制也可以在停滞性皮炎上产生皮肤溃疡。在适当的情况下,这种皮肤溃疡被称为“静脉性溃疡”,或者在不同的情况下称为“淤滞性溃疡”。静脉性溃疡和其他淤滞性溃疡之间的区别通常可以在床边进行。此外,静脉性溃疡和其他淤滞性溃疡的一些一般治疗措施是相似的:如弹性按压、局部皮肤护理和溃疡护理。由于具有共同的病理生理机制,具有临床相似性,并对相似的治疗做出反应,一个统一的概念可能适合包括瘀血性皮炎、静脉性溃疡和其他瘀血性溃疡。目前的工作就是为了达到这个目的。
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引用次数: 0
Etıology and Management of Lower Gastroıntestınal Bleedıng ın Neonates: A Revıew Artıcle 新生儿下消化道出血的病因和治疗:一篇综述
Pub Date : 2021-12-20 DOI: 10.31579/2690-1919/210
V. Erikçi
Lower gastrointestinal bleeding (LGIB) in neonates is occasionally encountered in clinical practice. There are various causative factors prodicing LGIB in neonates and the babies are usually managed with regard to the underlying pathology that produces LGIB. Although majority of these bleeding episodes is self limited, certain neonates with LGIB may necessitate prompt management including urgent surgical intervention. In this review article it is aimed to review the etiology, epidemiology, clinical manifestations and principles of treatment of LGIB in neonates under the light of relevant literature.
新生儿下消化道出血(LGIB)在临床实践中是偶尔遇到的。在新生儿中产生LGIB有各种各样的致病因素,婴儿通常根据产生LGIB的潜在病理进行管理。虽然大多数出血发作是自限性的,但某些LGIB新生儿可能需要及时处理,包括紧急手术干预。本文结合相关文献,对新生儿LGIB的病因、流行病学、临床表现及治疗原则进行综述。
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引用次数: 0
Prevalence and Predictive Factors of Induced Abortion among Women in Ghana: Data Analysis of Maternal Health Survey, 2017. 加纳妇女人工流产的患病率和预测因素:2017年孕产妇健康调查数据分析。
Pub Date : 2021-11-20 DOI: 10.31579/2690-1919/204
A. Alhassan, J. Anyinzaam-Adolipore
Induced abortion is a common practice for women worldwide; nevertheless, the practice of unsafe abortion rate in Ghana is in height and is a constant issue of public health concern. Objective: The main aim of the study was to identify predictive factors associated with induced abortion among women in Ghana. Methods: Ghana Maternal Health Survey data was used for this study to do an analytic cross-section study. Data analysis was done using SPSS version 20. The association between dependent and independent variables was explored using chi-square and logistic regression. Statistical significance was set at p < 0.05. Results: In this study, the prevalence of induced among the respondents was 14.8%, the prevalence was higher (25.5%) in Greater Accra Region and lower (3.2%) in Northern Region. All under-studied independent variables through chi-square analysis were associated with induced abortion with significance. However, in advance analysis through binary logistics regression model predictor factors of induced abortion in Ghana identified were; the age of the respondents’, region of orientation, religious affiliation, marital status, ethnicity, exposure to mobile phone and newspaper, and age at first sex. The logistic regression model appropriately explained the outcome variable (induced abortion) since the Hosmer-Lemeshow goodness-of-fit test p-value was more than 0.05 (X2 (8) = 4.428, P = .817). Conclusion: The prevalence of abortion in Ghana is still high, hence the need for increase public education on contraceptive use and the adverse effects of abortion through the use of modern media can go a long way to reduce the incidence of induced abortion in Ghana.
人工流产是全世界妇女的常见做法;然而,加纳的不安全堕胎率非常高,一直是公共卫生关注的问题。目的:本研究的主要目的是确定加纳妇女人工流产的预测因素。方法:本研究采用加纳孕产妇健康调查数据进行横断面分析研究。数据分析采用SPSS版本20。使用卡方和逻辑回归来探讨因变量和自变量之间的相关性。统计学显著性设定为p<0.05。结果:在本研究中,受访者中诱发的患病率为14.8%,大阿克拉地区的患病率较高(25.5%),北部地区较低(3.2%)。通过卡方分析,所有研究不足的自变量均与人工流产相关,具有显著性。然而,通过二元物流回归模型预先分析,加纳人工流产的预测因素有:;受访者的年龄、取向地区、宗教信仰、婚姻状况、种族、接触手机和报纸的情况以及初性年龄。逻辑回归模型适当地解释了结果变量(人工流产),因为Hosmer-Lemeshow拟合优度检验p值大于0.05(X2(8)=4.428,p=.817)。结论:加纳的堕胎率仍然很高,因此,需要通过使用现代媒体,加强关于避孕药具使用和堕胎不良影响的公共教育,这将大大有助于降低加纳人工流产的发生率。
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引用次数: 0
Nanostructures of Phospholipids on Articular Cartilage Surface and their Functions 关节软骨表面磷脂的纳米结构及其功能
Pub Date : 2021-11-20 DOI: 10.31579/2690-1919/205
Pawlak Pawlak, M. Sójka
Phospholipids bilayers fulfill an important role in natural joint lamellar-repulsive lubrication mechanism. Low friction between surfaces coated with negatively charged the phospholipid headgroup (–PO4-) as being due to a hydration layer. Wettability of the cartilage surface depends on the number of PLs that act as a lubricant. The cartilage can be classified as a group of intelligent material, which in the wet state has a contact angle of ~0º, and the air-dry state has a contact angle of ~104º.
磷脂双分子层在天然关节层排斥润滑机制中起着重要作用。由于水合层的存在,表面上涂有带负电荷的磷脂头基团(- po4 -),表面之间的摩擦很小。软骨表面的润湿性取决于作为润滑剂的PLs的数量。软骨可归类为一组智能材料,其在湿润状态下接触角为~0º,在风干状态下接触角为~104º。
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引用次数: 0
Multiple Sclerosis, Chlamydia and Gut Disbiosis 多发性硬化、衣原体和肠道疾病
Pub Date : 2021-11-20 DOI: 10.31579/2690-1919/208
J. Medina
I believe that multiple sclerosis progression could be stopped through antibiotics, dewormers, beta glucans and garlic extract and, by far the most difficult, changing the quality of the water ingested, or used for washing salads, in addition to increasing the consumption of probiotics. I believe that MS sclerosis is due to the unfortunate encounter of 3 diseases: intestinal dysbiosis, chlamydia infections and orthopedic problems. However, how would these three diseases cause demyelination of nerve fibers?
我相信,多发性硬化症的进展可以通过抗生素、驱虫剂、β-葡聚糖和大蒜提取物来阻止,而且最困难的是,除了增加益生菌的消耗外,还可以改变摄入或用于清洗沙拉的水的质量。我认为多发性硬化症是由于3种疾病的不幸遭遇:肠道生态失调、衣原体感染和骨科问题。然而,这三种疾病是如何导致神经纤维脱髓鞘的?
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引用次数: 0
Association between Flexible Nasal Endoscopy, Polysonography Findins and Obstructive Sleep Apnea Severety 柔性鼻内窥镜、多导成像结果与阻塞性睡眠呼吸暂停严重程度的关系
Pub Date : 2021-11-20 DOI: 10.31579/2690-1919/206
Zappelini Cem, Jeremias La, Borba In, Machado Lz, Nicoladelli Sj, Marcelino Tf
Introduction: Obstructive Sleep Apnea (OSA) is a condition with recurrent collapses of the pharyngeal region that result in partial or total reduction in airflow. Its diagnosis and severity depends on the Apnea-Hypopnea Index (AHI), data from the polysomnography exam (PSG). Its pathophysiology includes anatomical disorders of the upper airways that can be assessed through Flexible Nasofibroscopy (FN). Objective: To identify the alterations present in the tests of FN and PSG in patients with OSA and correlate with the AHI. Methods: Cross-sectional study, with data collected from reports of the FN and PSG exams of 81 patients with OSA, seen at an otorhinolaryngology clinic in Tubarão - SC. It was verified the association between the outcome –AHI- and other exposure variables - sociodemographic and clinical. Results: Among the 81 patients, 75.31% were male, 41.98% had mild apnea, 30.86% moderate and 27.16% severe apnea. There was no correlation between FN findings and AHI (p> 0.05). There was a difference between the mean age, number of obstructive episodes per hour of sleep and minimum saturation between the groups with severe and mild apnea (p <0.05). Patients with severe apnea had a higher percentage of sleep phase one and a shorter REM sleep time compared to the mild apnea group (p <0.05). A positive correlation was obtained between: obstructive episodes with sleep stage 1 (p <0.01) and age (p <0.05); between minimum saturation and sleep stage 3 (p <0.05). There was an inverse correlation between obstructive episodes with minimal saturation (p <0.001), with sleep stage 3 (p <0.01) and with REM sleep (p <0.01); between age and minimum saturation (p <0.01). Conclusion: OSA directly interferes with sleep architecture. The present study did not find association between upper airway alterations and OSA severity.
梗阻性睡眠呼吸暂停(OSA)是一种咽部反复塌陷导致部分或全部气流减少的病症。其诊断和严重程度取决于呼吸暂停低通气指数(AHI),多导睡眠图检查(PSG)的数据。其病理生理包括可通过柔性鼻纤维镜(FN)评估的上气道解剖紊乱。目的:探讨OSA患者FN和PSG检测的变化及其与AHI的相关性。方法:横断面研究,收集来自tubar o - SC的一家耳鼻喉科诊所的81例OSA患者的FN和PSG检查报告的数据,验证结果- ahi -与其他暴露变量-社会人口学和临床之间的关联。结果:81例患者中男性占75.31%,轻度呼吸暂停占41.98%,中度呼吸暂停占30.86%,重度呼吸暂停占27.16%。FN与AHI无相关性(p < 0.05)。重度和轻度呼吸暂停组的平均年龄、每小时睡眠阻塞发作次数和最低饱和度差异有统计学意义(p <0.05)。重度呼吸暂停患者的第一阶段睡眠比例高于轻度呼吸暂停组,REM睡眠时间较短(p <0.05)。睡眠阶段1阻塞性发作与年龄呈正相关(p <0.01);最低饱和度与睡眠阶段3之间的差异(p <0.05)。阻塞性发作与最低饱和度(p <0.001)、睡眠阶段3 (p <0.01)和快速眼动睡眠(p <0.01)呈负相关;年龄与最小饱和度之间有显著差异(p <0.01)。结论:OSA直接干扰睡眠结构。本研究未发现上呼吸道改变与OSA严重程度之间的关联。
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引用次数: 0
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Journal of clinical research and reports
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