Vandana Chaudhary, S. Hussain, V. Jain, V. Prakash, R. Khar, Sushruti Sharma
{"title":"Formulation and Characterization of Solid Lipid Nanoparticles Containing Artemether and Lumefantrine for Treatment of P. falciparum","authors":"Vandana Chaudhary, S. Hussain, V. Jain, V. Prakash, R. Khar, Sushruti Sharma","doi":"10.9734/BJPR/2017/26483","DOIUrl":"https://doi.org/10.9734/BJPR/2017/26483","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"35 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82234072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Gholami, S. Khabnadideh, Y. Ghasemi, B. Mirjalili, Roozbeh Shahmoradi, L. Zamani
{"title":"TiCl4/nano-sawdust as an Efficient Biocatalyst for the Synthesis of Highly Substituted Dihydro- 2-oxopyrroles as Antimicrobial Agents","authors":"A. Gholami, S. Khabnadideh, Y. Ghasemi, B. Mirjalili, Roozbeh Shahmoradi, L. Zamani","doi":"10.9734/BJPR/2017/33030","DOIUrl":"https://doi.org/10.9734/BJPR/2017/33030","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"3 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91053767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative Study of Antioxidant and Anticancer Activity of Thuja orientalis Growing in Egypt and Saudi Arabia","authors":"Eman Ramadan Elsharkawy, H. Al-Johar, A. Donia","doi":"10.9734/BJPR/2017/32387","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32387","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"40 1","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88894316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Patient Controlled-epidural Analgesia with or without a Background Infusion for Labour Analgesia","authors":"Figen Önder, N. Kayacan, B. Karsli, Z. Bigat","doi":"10.9734/BJPR/2017/31717","DOIUrl":"https://doi.org/10.9734/BJPR/2017/31717","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"78 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89044336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Fatima, A. Syed, S. Azhar, M. Dawood, S. Bashir
{"title":"Medical Students Perception and Practice of Self-medication: Vision of Future Practitioner in Pakistan","authors":"S. Fatima, A. Syed, S. Azhar, M. Dawood, S. Bashir","doi":"10.9734/BJPR/2017/32524","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32524","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"87 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74519787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Said, Y. Tamimi, Akhtar, A. M. Weli, Suleiman Al-Khanjari, Qassim Al-Riyami
This paper reports in vitro anticancer activity of hexane, chloroform, ethyl acetate, butanol and water extracts obtained from twelve (12) medicinal plants including Aloe dhufarensis, Calotropis procera, Juniperus servaschanica, Lawsonia inermis, Maytenus dhofarensis, Moringa peregrina, Polygala senensis, Punica granatum, Rhazya stricta, Solanum incanum, Teucrium mascatense. and Zataria multiflora collected from Oman. Crude ethanol extracts prepared by maceration of plant materials in ethanol were Kupchan partitioned to give hexane, chloroform, ethyl acetate, butanol and aqueous fractions. Cytotoxicities of the prepared fractions were measured by Alamar blue assay against ovarian cancer cell line (MCAS) and breast cancer cell line (MDA MB231). Thirteen extracts from five plants C. procera, J. servaschanica, M. dhofarensis, S. incanum and Original Research Article Said et al.; BJPR, 15(5): 1-8, 2017; Article no.BJPR.32459 2 T. mascatense were found active against MCAS; hexane extract from J. servaschanica was the most active followed by chloroform extract from leaves of S. incanum (IC50 = 8.50 and 10.90 μg/ml, respectively). Furthermore, nine extracts from these plants except C. procera inhibited the growth of MDA MB321; hexane extract from J. servaschanica was again the most active followed by butanol extract of S. incanum. (IC50 = 11.4 and 19.44 μg/ml, respectively). Ethnobotanical and ethnopharmacological information on flora growing in this intemperate, hot climate region could provide new chemical entities for development of new and more potent cancer chemotherapeutics.
{"title":"In vitro Anticancer Activity of Selected Medicinal Plants from Oman","authors":"S. Said, Y. Tamimi, Akhtar, A. M. Weli, Suleiman Al-Khanjari, Qassim Al-Riyami","doi":"10.9734/BJPR/2017/32459","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32459","url":null,"abstract":"This paper reports in vitro anticancer activity of hexane, chloroform, ethyl acetate, butanol and water extracts obtained from twelve (12) medicinal plants including Aloe dhufarensis, Calotropis procera, Juniperus servaschanica, Lawsonia inermis, Maytenus dhofarensis, Moringa peregrina, Polygala senensis, Punica granatum, Rhazya stricta, Solanum incanum, Teucrium mascatense. and Zataria multiflora collected from Oman. Crude ethanol extracts prepared by maceration of plant materials in ethanol were Kupchan partitioned to give hexane, chloroform, ethyl acetate, butanol and aqueous fractions. Cytotoxicities of the prepared fractions were measured by Alamar blue assay against ovarian cancer cell line (MCAS) and breast cancer cell line (MDA MB231). Thirteen extracts from five plants C. procera, J. servaschanica, M. dhofarensis, S. incanum and Original Research Article Said et al.; BJPR, 15(5): 1-8, 2017; Article no.BJPR.32459 2 T. mascatense were found active against MCAS; hexane extract from J. servaschanica was the most active followed by chloroform extract from leaves of S. incanum (IC50 = 8.50 and 10.90 μg/ml, respectively). Furthermore, nine extracts from these plants except C. procera inhibited the growth of MDA MB321; hexane extract from J. servaschanica was again the most active followed by butanol extract of S. incanum. (IC50 = 11.4 and 19.44 μg/ml, respectively). Ethnobotanical and ethnopharmacological information on flora growing in this intemperate, hot climate region could provide new chemical entities for development of new and more potent cancer chemotherapeutics.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"89 1","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84223155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Venkatachalam, M. Harsha, M. Pooja, M. Paranjothy, R. Kumar
{"title":"Enhanced bio-adhesion and sustained delivery of Clotrimazole encapsulated solid lipid nanoparticles loaded in hyaluronic acid gel as anti-fungal therapy","authors":"S. Venkatachalam, M. Harsha, M. Pooja, M. Paranjothy, R. Kumar","doi":"10.9734/BJPR/2017/34063","DOIUrl":"https://doi.org/10.9734/BJPR/2017/34063","url":null,"abstract":"","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"3 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89800178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Karaveli, N. Ozturk, A. S. Kavakli, G. Çakmak, A. A. Onuk, K. İnanoğlu, B. Karsli
Osteogenesis imperfecta is a rare genetic disorder and a collagen tissue disease for which preoperative preparation and intra-operative anesthesia management must be performed with great care on patients. An operation was planned for a 5-year old female patient with Type I osteogenesis imperfecta due to a right femoral fracture. Her medical history showed that she had been operated due to a left femoral fracture 5 months ago under sevoflurane inhalation anesthesia without any complications. On her physical examination, she was observed to be a short child with growth deficiency, kyphoscoliosis, and bone and shape deformities on her extremities. Her modified Mallampati score was III and neck extension was limited. Preoperative echocardiography, complete blood cell count, coagulation profile, and biochemical values were found in normal limits. She was taken into the Case Study Karaveli et al.; BJPR, 15(5): 1-5, 2017; Article no.BJPR.31703 2 operation theatre and monitorized. Pressure points were supported by silicon peds. Vascular access could not be established at first because of her agitation, and then it was achieved after the patient’s anesthesia induction was performed with sevoflurane. Her neck was kept stable and laryngeal mask was placed in the mouth in the first intervention. Anesthesia was provided through 50% O2 + 50% air and 2% sevoflurane. At the end of the operation that took 90 min, the patient was extubated unevenBtfully, and taken to the recovery room. Main anesthetic problems in patients with osteogenesis imperfecta are the difficulties in maintaining the airway management and malign hyperthermia. We used sevoflurane both at the induction and at the maintenance of anaesthesia due to the difficult vascular access of the patient, and we did not encounter any problems. Inhalation anesthesia such as sevoflurane as well as TIVA could be used for the anesthesia for the patients with osteogenesis imperfecta. Great care must be given because of difficult airway in such patients, and necessary precautions must be taken. Laryngeal mask airway could be preferred in order to secure the airway and avoid traumatic complications.
{"title":"Anesthesia Management in Rare Case: Osteogenesis Imperfecta","authors":"A. Karaveli, N. Ozturk, A. S. Kavakli, G. Çakmak, A. A. Onuk, K. İnanoğlu, B. Karsli","doi":"10.9734/BJPR/2017/31703","DOIUrl":"https://doi.org/10.9734/BJPR/2017/31703","url":null,"abstract":"Osteogenesis imperfecta is a rare genetic disorder and a collagen tissue disease for which preoperative preparation and intra-operative anesthesia management must be performed with great care on patients. An operation was planned for a 5-year old female patient with Type I osteogenesis imperfecta due to a right femoral fracture. Her medical history showed that she had been operated due to a left femoral fracture 5 months ago under sevoflurane inhalation anesthesia without any complications. On her physical examination, she was observed to be a short child with growth deficiency, kyphoscoliosis, and bone and shape deformities on her extremities. Her modified Mallampati score was III and neck extension was limited. Preoperative echocardiography, complete blood cell count, coagulation profile, and biochemical values were found in normal limits. She was taken into the Case Study Karaveli et al.; BJPR, 15(5): 1-5, 2017; Article no.BJPR.31703 2 operation theatre and monitorized. Pressure points were supported by silicon peds. Vascular access could not be established at first because of her agitation, and then it was achieved after the patient’s anesthesia induction was performed with sevoflurane. Her neck was kept stable and laryngeal mask was placed in the mouth in the first intervention. Anesthesia was provided through 50% O2 + 50% air and 2% sevoflurane. At the end of the operation that took 90 min, the patient was extubated unevenBtfully, and taken to the recovery room. Main anesthetic problems in patients with osteogenesis imperfecta are the difficulties in maintaining the airway management and malign hyperthermia. We used sevoflurane both at the induction and at the maintenance of anaesthesia due to the difficult vascular access of the patient, and we did not encounter any problems. Inhalation anesthesia such as sevoflurane as well as TIVA could be used for the anesthesia for the patients with osteogenesis imperfecta. Great care must be given because of difficult airway in such patients, and necessary precautions must be taken. Laryngeal mask airway could be preferred in order to secure the airway and avoid traumatic complications.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"56 1","pages":"1-5"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89826201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Bahmani, S. M. Mahmoodabad, B. Enjezab, M. Askarshahi, M. Baghianimoghadam
Background: Decision making for adopting a health behavior is a process involving passing through different stages. Objectives: This study was conducted to determine the decision-making stages based on Precaution Adoption Process Model (PAPM) in Pap test in rural women. Methods: This study was conducted implementing a quasi-experimental method. The participants were divided into two groups as experimental and control groups using the Precaution Adoption Process Model (PAPM) among 180 rural females in Sarvabad. In treating the experimental group, the methods of lecturing with question and answer, playing videos, specialized consulting and Original Research Article Bahmani et al.; BJPR, 16(6): 1-7, 2017; Article no.BJPR.32965 2 pamphlet were used. The data gathering tool included a questionnaire consisting a demographic variables and variables affecting the stages of PAPM. Data analysis was performed using the Mann-Whitney, chi-square and descriptive statistical methods. Results: The results showed that 45% of the participants found their way to the sixth stage, i.e., practice stage (doing Pap smear). In comparison of the means of the scores of psychological variables affecting the decision process in Pap smear test, there was a significant relationship between the experimental and control groups based on Mann-Whitney test and control groups based on variables, perceived susceptibility, perceived benefits, perceived barriers, perceived selfefficacy and awareness. But the perceived severity was not statistically significant. Chance of entering the sixth stage in the intervention group was 2.5 times higher than the control group. Conclusions: Females for Pap smear at the same stage of the decision were not on the same basis. Thus, educational interventions should be done at each stage.
{"title":"The Effect of Training Based on Precaution Adoption Process Model (PAPM) on Rural Females’ Participation in Pap smear","authors":"A. Bahmani, S. M. Mahmoodabad, B. Enjezab, M. Askarshahi, M. Baghianimoghadam","doi":"10.9734/BJPR/2017/32965","DOIUrl":"https://doi.org/10.9734/BJPR/2017/32965","url":null,"abstract":"Background: Decision making for adopting a health behavior is a process involving passing through different stages. Objectives: This study was conducted to determine the decision-making stages based on Precaution Adoption Process Model (PAPM) in Pap test in rural women. Methods: This study was conducted implementing a quasi-experimental method. The participants were divided into two groups as experimental and control groups using the Precaution Adoption Process Model (PAPM) among 180 rural females in Sarvabad. In treating the experimental group, the methods of lecturing with question and answer, playing videos, specialized consulting and Original Research Article Bahmani et al.; BJPR, 16(6): 1-7, 2017; Article no.BJPR.32965 2 pamphlet were used. The data gathering tool included a questionnaire consisting a demographic variables and variables affecting the stages of PAPM. Data analysis was performed using the Mann-Whitney, chi-square and descriptive statistical methods. Results: The results showed that 45% of the participants found their way to the sixth stage, i.e., practice stage (doing Pap smear). In comparison of the means of the scores of psychological variables affecting the decision process in Pap smear test, there was a significant relationship between the experimental and control groups based on Mann-Whitney test and control groups based on variables, perceived susceptibility, perceived benefits, perceived barriers, perceived selfefficacy and awareness. But the perceived severity was not statistically significant. Chance of entering the sixth stage in the intervention group was 2.5 times higher than the control group. Conclusions: Females for Pap smear at the same stage of the decision were not on the same basis. Thus, educational interventions should be done at each stage.","PeriodicalId":9320,"journal":{"name":"British journal of pharmaceutical research","volume":"16 1","pages":"1-7"},"PeriodicalIF":0.0,"publicationDate":"2017-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78313949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：