Journal of hazardous materials letters最新文献_第4页

Exploring the impact of copper oxide nanoparticles on the biocontrol activity and plant growth promotion of Trichoderma asperellum 探讨氧化铜纳米颗粒对曲霉木霉生防活性及促进植株生长的影响

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-02-19 DOI: 10.1016/j.hazl.2025.100147

Claudia A. Ramírez-Valdespino , Marlyn Morales-García , Guillermo Herrera-Pérez , Yordan J. Romero-Contreras , Enrique García-Mireles , Joan Salas-Leiva , Susana González-Chávez , Socorro Tarango-Rivero , Erasmo Orrantia-Borunda

Agriculture is constantly in the search for new alternatives to control phytopathogens and improvement of plant growth. One of its main strategies is the use of biocontrollers, among them, Trichoderma genus stand out for their versatility and broad spectrum phytopatogenic fungi attacked. On the other hand, nanotechnology is positioning itself as an alternative to the use of agrochemicals, especially metal oxide nanoparticles, including ZnO, TiO₂ and CuO. Recently, it has been seen that when Trichoderma is put in contact with nanoparticles, it increases its biocontrol and biostimulant activity. Therefore, in this work we performed the characterization of a T. asperellum strain, which was capable to grow in different concentrations of CuO nanoparticles, obtaining that, at 200 ppm, Trichoderma showed no changes in growth and no apparent stress. Moreover, the strain developed a higher biocontrol activity against two Fusarium oxysporum strains, but decreases with F. fujikuroi, as well as changes in the expression of genes associated to biocontrol. Finally, an enhance in alfalfa growth is reported. These results suggest that, at the tested concentrations, CuO-NPs do not interfere with the biocontrol activity of T. asperellum, providing the basis for the development of a bionanoformulation to control F. oxysporum and promotes alfalfa growth.

农业一直在不断寻找新的替代方法来控制植物病原体和改善植物生长。其主要策略之一是使用生物防治剂，其中木霉属以其多功能性和广谱的植物性真菌攻击而突出。另一方面，纳米技术将自己定位为农用化学品的替代品，特别是金属氧化物纳米粒子，包括ZnO、TiO2和CuO。最近，人们发现当木霉与纳米颗粒接触时，它的生物防治和生物刺激素活性增加。因此，在这项工作中，我们对一株能够在不同浓度的CuO纳米颗粒中生长的曲霉菌株进行了表征，结果表明，在200 ppm的浓度下，木霉的生长没有变化，也没有明显的胁迫。此外，该菌株对两种尖孢镰刀菌均有较高的生物防治活性，但对fujikuroi和生物防治相关基因表达的变化均有抑制作用。最后，报道了苜蓿生长的增强。这些结果表明，在测试浓度下，CuO-NPs不会干扰曲霉的生物防治活性，为开发防治尖孢镰刀菌和促进苜蓿生长的生物纳米制剂提供了基础。

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引用次数: 0

Parental BPA exposure disrupts offspring transcriptomic profiles and impairs embryonic lineage specification during zygotic genome activation 父母双酚a暴露破坏后代转录组谱和损害胚胎谱系规范在合子基因组激活

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-02-18 DOI: 10.1016/j.hazl.2025.100146

Yuequn Chen , Kusheng Wu , Wenlong Huang

Bisphenol A (BPA) is an endocrine-disrupting chemical known for its developmental toxicity. However, the impact of BPA on early embryonic development, particularly during zygotic genome activation (ZGA), remains underexplored. In this study, zebrafish embryos at 3.5 and 4.5 hours post-fertilization (hpf) were collected after 7-day parental exposure to 1.0 µM BPA for transcriptome sequencing. Transcriptomic data underwent differential gene expression functional enrichment and gene set enrichment analyses. Public single-cell transcriptome atlases of zebrafish embryos at different developmental stages (3.3, 4, and 4.8 hpf) were obtained to build signature matrices for digital cell type sorting of the bulk transcriptome using the CIBERSORTx algorithm. Results indicated that parental BPA exposure resulted in muted gene expression response, disturbed energy metabolism profile, and increased pro-inflammatory signatures during ZGA. Digital cell type deconvolution revealed altered cell composition, including deeper multilayer and enveloping layer cells and fewer margin cells. Furthermore, reductions in neural progenitor and heart primordium lineages, alongside expansions in primordial germ and mesendodermal lineages, potentially contribute to later-stage developmental abnormalities. This study elucidates the embryotoxic effects of BPA during the ZGA period, shedding light on the developmental perturbations from early-life exposure to this ubiquitous environmental contaminant.

双酚A （BPA）是一种内分泌干扰化学物质，以其发育毒性而闻名。然而，BPA对早期胚胎发育的影响，特别是在合子基因组激活（ZGA）期间，仍未得到充分研究。在本研究中，父母暴露于1.0 µM BPA 7天后，采集受精后3.5和4.5 小时（hpf）的斑马鱼胚胎进行转录组测序。转录组学数据进行了差异基因表达、功能富集和基因集富集分析。获取不同发育阶段（3.3、4和4.8 hpf）的斑马鱼胚胎的公开单细胞转录组图谱，利用CIBERSORTx算法构建标记矩阵，用于批量转录组的数字细胞类型分选。结果表明，父母双酚a暴露导致ZGA期间基因表达反应减弱，能量代谢谱紊乱，促炎特征增加。数字细胞类型反褶积显示细胞组成改变，包括多层和包络层细胞变深，边缘细胞变少。此外，神经祖细胞和心脏原基谱系的减少，以及原始生殖细胞和中胚层谱系的扩张，可能导致后期发育异常。本研究阐明了双酚a在ZGA时期的胚胎毒性作用，揭示了早期暴露于这种普遍存在的环境污染物对发育的干扰。

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引用次数: 0

Pyrethroids have become a barrier to the daily existence of molluscs (Review) 拟除虫菊酯已成为软体动物日常生存的障碍（回顾）

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-02-16 DOI: 10.1016/j.hazl.2025.100144

Raja Saha , Sangita Maiti Dutta

Molluscs are significant aquatic organisms, which serve as bioindicator species. They are crucial for maintaining ecological balance as secondary consumers. Molluscs are threatened by pesticides such as pyrethroid insecticides. Pyrethroids are increasingly utilized to control insects in agriculture and gardening. It contaminates aquatic bodies through rainwater runoff and drainage-sewage systems. The current review will focus on the issue of increasing pyrethroid use and its biological effects on molluscs. Due to their highly lipophilic nature, pyrethroids pose a significant risk to these organisms by affecting their metabolites, producing reactive oxygen species, and influencing neurotransmitter actions. The threats to the molluscs and eventually to the concerned aquatic ecosystem warrant significant discussion and attention.

软体动物是重要的水生生物，是生物指示物种。他们作为次级消费者对维持生态平衡至关重要。软体动物受到杀虫剂的威胁，例如拟除虫菊酯杀虫剂。拟除虫菊酯类杀虫剂越来越多地用于农业和园艺中的昆虫防治。它通过雨水径流和排水污水系统污染水体。目前的审查将侧重于增加使用拟除虫菊酯类杀虫剂的问题及其对软体动物的生物学影响。由于其高度亲脂性，拟除虫菊酯通过影响这些生物的代谢物、产生活性氧和影响神经递质作用，对这些生物构成重大风险。对软体动物和水生生态系统的威胁值得讨论和关注。

引用次数: 0

Toxicological assessment & risk evaluation of pesticides and their mixtures through C. elegans & RISK21: A risk-based approach for sustainable agriculture 通过秀丽隐杆线虫进行农药及其混合物的毒理学评估和风险评估& RISK21：可持续农业的基于风险的方法

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-02-12 DOI: 10.1016/j.hazl.2025.100145

Mariana I. Manetti , M. Laura Migliori , M. Florencia Kronberg , Rosana Rota , Aldana Moya , Eduardo A. Pagano , Daniel H. Calvo , Sandrine Deglin , Michelle Embry , Diego A. Golombek , Eliana R. Munarriz

Pesticides are extensively used in agriculture to protect crops, but their environmental release, particularly as mixtures, raises concerns about effects on non-target organisms and ecosystem health. This study aimed to evaluate the toxicity of five pesticides used extensively on soybean crops - glyphosate, 2,4-D, paraquat, chlorpyrifos, and lambda-cyhalothrin- and their binary mixtures on the nematode Caenorhabditis elegans, a model organism in toxicology. Locomotion and growth assays were conducted to assess acute and chronic effects, and the RISK21 matrix framework was used to convey environmental risks based on the bioassay results combined with surface water monitoring data and modeled exposure estimates. Our results demonstrate significant reductions in locomotion and body length for all tested pesticides, with synergistic effects observed in binary mixtures. However, the risk-based analysis suggests that the estimated environmental concentrations of these pesticides pose minimal ecological risks. In conclusion, our work highlights the novelty of combining C. elegans-based toxicity assays in a risk-based approach to evaluate pesticide mixtures, offering a practical approach for predicting environmental impacts and promoting sustainable agriculture.

农药在农业中广泛用于保护作物，但它们的环境释放，特别是作为混合物，引起了对非目标生物和生态系统健康影响的担忧。本研究旨在评价大豆作物上广泛使用的草甘膦、2,4- d、百草枯、毒死蜱和高效氯氟氰菊酯五种农药及其二元混合物对毒理学模式生物秀丽隐杆线虫的毒性。通过运动和生长试验来评估急性和慢性影响，并使用RISK21矩阵框架来传达基于生物测定结果、地表水监测数据和建模暴露估计的环境风险。我们的研究结果表明，所有被测农药的运动和体长都显著减少，在二元混合物中观察到协同效应。然而，基于风险的分析表明，这些农药的估计环境浓度构成最小的生态风险。总之，我们的工作突出了将基于秀丽隐杆线虫的毒性试验与基于风险的方法相结合来评估农药混合物的新颖性，为预测环境影响和促进可持续农业提供了一种实用的方法。

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引用次数: 0

Visualization and spatial mapping of PFAS in the edible storage root of radish 萝卜可食贮藏根中PFAS的可视化与空间制图

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-02-01 DOI: 10.1016/j.hazl.2025.100141

Yuwei Zuo, Weilan Zhang

Plants, as key components of trophic networks, play a critical role in the bioaccumulation of PFAS and their transfer to higher trophic levels. This study introduces an innovative methodology using timsTOF fleX MALDI-2 to visualize the spatial distribution of PFAS in plant tissues. Radish was selected as the model plant due to its global popularity as a widely consumed vegetable. DAN (1,5-diaminonaphthalene) was used as the MALDI matrix, and the mass spectrometry operating conditions were optimized to acquire the best PFAS signals. The results show that long-chain PFAS predominantly accumulated in the xylem of the edible storage root, where their high hydrophobicity limits upward translocation. In contrast, short-chain PFAS and PFOA exhibited stronger signals in the cortex and periderm, likely due to alternative transport pathways. This differential distribution highlights the significant influence of PFAS physicochemical properties, such as chain length and hydrophobicity, on their in-planta transport mechanisms. By precisely mapping PFAS within plant tissues, this study provides a powerful tool for identifying high-risk edible tissues and assessing human exposure risks through PFAS-contaminated crops. It also reinforces the urgent need for sustainable remediation strategies to reduce PFAS levels in agricultural systems, thereby safeguarding food safety, ecosystem health, and human well-being.

植物作为营养网络的关键组成部分，在PFAS的生物积累和向更高营养水平的转移中起着关键作用。本研究介绍了一种创新的方法，使用timsTOF fleX MALDI-2来可视化植物组织中PFAS的空间分布。萝卜作为一种广泛食用的蔬菜，在全球范围内广受欢迎，因此被选为示范植物。以DAN（1,5-二氨基萘）为MALDI基质，优化质谱操作条件，获得最佳PFAS信号。结果表明，长链PFAS主要积聚在可食贮藏根的木质部，其高疏水性限制了其向上转运。相比之下，短链PFAS和PFOA在皮层和外周表现出更强的信号，可能是由于不同的运输途径。这种差异分布突出了PFAS的理化性质（如链长和疏水性）对其在植物内运输机制的显著影响。通过对植物组织中PFAS的精确定位，本研究为识别高风险食用组织和评估人类通过PFAS污染作物暴露的风险提供了有力的工具。它还强调迫切需要制定可持续补救战略，以减少农业系统中全氟磺酸的水平，从而保障食品安全、生态系统健康和人类福祉。

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引用次数: 0

Elevated concentrations of quaternary ammonium compounds in childcare centers: A pilot study 托儿中心季铵化合物浓度升高：一项初步研究

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2025-01-02 DOI: 10.1016/j.hazl.2024.100138

Yao Cheng , Zhong Lv , Erika Schreder , Min Hu , Abby Mutic , Guomao Zheng , Amina Salamova

Quaternary ammonium compounds (QACs) are used as antimicrobials, preservatives, and antistatic agents in cleaning, disinfecting and personal care products, and textiles. High levels of QACs have been found in indoor dust in residential homes; however, there is limited information on QAC exposure in non-residential environments serving sensitive populations, such as childcare centers. In this study, we investigated the occurrence of QACs, including benzylalkyldimethyl ammonium compounds (BACs), dialkyldimethylammonium compounds (DADMACs), and alkyltrimethylammonium compounds (ATMACs), in dust from childcare centers and estimated daily intake of QACs by toddlers in chidlcare via dust ingestion. Nineteen QACs were detected in dust with a median total QAC concentration (ΣQAC) of 150 μg/g. BACs were the most abundant QAC group found at concentrations ranging from 2.67 to 1370 μg/g (median 90.4 μg/g) and constituted 64 % of the ΣQAC concentrations. The QAC levels in dust from childcare centers were significantly higher than concentrations previosly reported in homes. The EDIs for BACs, DADMACs, and ATMACs via dust ingestion calculated based on the 95th percentile concentrations in childcare dust were up to 30 times higher than those for toddlers in residential homes. These findings demonstrate high QAC exposure in childcares, posing significant early-life exposure for toddlers.

季铵化合物（QACs）在清洁、消毒和个人护理产品以及纺织品中用作抗菌剂、防腐剂和抗静电剂。在住宅的室内灰尘中发现了高水平的QACs；然而，在服务于敏感人群（如托儿中心）的非住宅环境中，有关QAC暴露的信息有限。在这项研究中，我们调查了包括苯烷基二甲基铵化合物（BACs）、二烷基二甲基铵化合物（dadmac）和烷基三甲基铵化合物（atmac）在内的QACs在托儿中心灰尘中的发生情况，并通过灰尘摄入估计了幼儿每日QACs的摄入量。粉尘中检测到19种QAC， QAC总浓度中位数（ΣQAC）为150 μg/g。在浓度范围为2.67 ~ 1370 μg/g（中位数为90.4 μg/g）时，BACs是最丰富的QAC组，占ΣQAC浓度的64 %。托儿所灰尘中的QAC水平明显高于之前报道的家庭浓度。根据儿童保育粉尘中第95百分位浓度计算的吸入粉尘中BACs、dadmac、atmac的EDIs比居住家庭的幼儿高出30倍。这些研究结果表明，幼儿在幼儿时期暴露于高质量空气质量物质。

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引用次数: 0

No traces of emerging and priority organic pollutants in the muscles of Procambarus clarkii suggest the feasibility of its regulated and sustainable control from uncontaminated environments 在克氏原螯虾的肌肉中没有新出现的和优先存在的有机污染物的痕迹，这表明在未受污染的环境中对其进行调控和可持续控制是可行的

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2024-12-30 DOI: 10.1016/j.hazl.2024.100140

Dario Savoca , Vincenzo Arizza , Gaetano Cammilleri , Leonardo Cerasino , Antonella Maccotta , Federico Marrone , Licia Pantano , Nico Salmaso , Francesco Paolo Faraone

A monitoring of organic contaminants in the muscles of the Procambarus clarkii and environmental samples of water and sediment was conducted in three Sicilian wetlands (Italy). The substances investigated in the biological samples were per- and polyfluoroalkyl substances (PFAS), phthalic acid esters (PAEs), pesticides, antibiotics, and microcystins (MCs), all of which were below the detection limit. Given that the Louisiana red swamp crayfish is considered a bioaccumulator, the results of this study indicate that these environments are not significantly contaminated by the selected pollutants. Furthermore, the study suggests the potential uses of the edible portions of this alien species. Despite P. clarkii cannot be marketed in several countries, including Italy, it is possible that the animal biomass obtained in the frame of the monitoring, control and eradication activities carried out by local authorities, could be exploited for various purposes, such as food, feed and biotechnology. This would reduce the costs associated with disposal and make these activities more sustainable in the long term, thereby contributing to the preservation of ecosystems that are currently threatened by this invasive species.

在意大利西西里的三个湿地对克氏原螯虾（Procambarus clarkii）肌肉中的有机污染物以及水和沉积物环境样本进行了监测。生物样品中检测的物质有全氟烷基和多氟烷基物质（PFAS）、邻苯二甲酸酯（PAEs）、农药、抗生素和微囊藻毒素（MCs），均低于检测限。考虑到路易斯安那州的红沼泽小龙虾被认为是一种生物蓄积器，本研究的结果表明，这些环境没有受到所选污染物的显著污染。此外，该研究还提出了这种外来物种可食用部分的潜在用途。尽管克拉氏杆菌不能在包括意大利在内的一些国家销售，但在地方当局开展的监测、控制和根除活动中获得的动物生物量有可能被用于各种目的，如食品、饲料和生物技术。这将减少与处理相关的成本，并使这些活动在长期内更具可持续性，从而有助于保护目前受到这种入侵物种威胁的生态系统。

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引用次数: 0

New Approach Methodologies: Physiological responses of daphnids to pharmaceutical mixtures 新方法方法：水蚤对药物混合物的生理反应

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2024-12-28 DOI: 10.1016/j.hazl.2024.100139

Emma Rowan , Anne Leung , Katie O’Rourke , Xiaofei Yin , Lorraine Brennan , Konstantinos Grintzalis

Conventional methods for water monitoring are insufficient to capture the impacts of pollution because of their sensitivity limits, while they also fail to provide mechanistic insight regarding the actions of pollutants. On the other hand, New Approach Methodologies are more and more introduced as supplementary tools that provide sensitive metrics for pollution assessment. In this context, freshwater sentinel species commonly known as water fleas were used to assess the impact of a pharmaceutical mixture. The pharmaceutical cocktail comprised of representatives of commonly encountered pharmaceuticals and specifically diclofenac, metformin, gabapentin, amoxicillin, trimethoprim, and erythromycin. Combining toxicity, phenotypic and molecular endpoints, results showed differences in mortality, feeding, key enzyme activities and metabolic perturbations, thus supporting a distinct pattern in physiological responses of daphnids that could be used to monitor and predict pollution early.

传统的水监测方法由于其灵敏度限制而不足以捕捉污染的影响，同时它们也不能提供有关污染物作用的机制见解。另一方面，越来越多地引入新方法方法作为补充工具，为污染评估提供敏感的指标。在这种情况下，通常称为水蚤的淡水哨兵物种被用来评估药物混合物的影响。药物鸡尾酒由常见药物的代表组成，特别是双氯芬酸、二甲双胍、加巴喷丁、阿莫西林、甲氧苄啶和红霉素。综合毒性、表型和分子终点，结果显示了水蚤在死亡率、摄食、关键酶活性和代谢扰动方面的差异，从而支持了水蚤生理反应的独特模式，可用于早期监测和预测污染。

引用次数: 0

Per- and polyfluoroalkyl substances in rainfall runoff from an AFFF-impacted concrete pad: A field simulation study 受afff影响的混凝土垫块降雨径流中的全氟和多氟烷基物质：一项实地模拟研究

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2024-11-28 DOI: 10.1016/j.hazl.2024.100137

Phong K. Thai , Jeffrey T. McDonough , Trent A. Key , Anita Thapalia , Scott Porman , Pritesh Prasad , Stephanie Fiorenza , Hirozumi Watanabe , Craig M. Barnes , Jochen F. Mueller

Per- and polyfluoroalkyl substances (PFAS) retained within hardscape have been observed to leach over time in numerous laboratory studies. The aim of this study was to measure the release of key PFAS in rainfall runoff from a concrete pad impacted by historical AFFF use at the field-scale. Rainfall simulations were conducted on a 5 m² (1 ×5 m) plot for 3 consecutive days. Runoff water was collected every 2 minutes and analyzed for 5 PFAS commonly associated with AFFF. Surface samples of the concrete were collected from the plot after the rainfall runoff experiment. Perfluorooctane sulfonate (PFOS) exhibited the highest concentrations within the concrete (up to ∼4000 μg kg⁻¹) and runoff water (up to 500 μg L⁻¹), followed by 6:2 fluorotelomer sulfonate (6:2 FTS). PFAS concentrations in runoff water were higher in the first sample and then decreased in the consecutive samples of each rainfall simulation. It is estimated that the percentage of the total PFAS mass within the surface of the concrete contributing to runoff samples ranged from 0.006 % (PFOS) to 0.031 % (PFHxA) per rainfall event. This suggests low but sustained PFAS leaching from AFFF-impacted concrete into runoff water. Our findings confirmed that concrete impacted by legacy use of AFFF is a likely secondary source of PFAS in runoff water and highlight some similarities and differences between laboratory- and field-scale rainfall simulations.

在许多实验室研究中，已观察到保留在硬景观中的全氟烷基和多氟烷基物质（PFAS）随着时间的推移会浸出。本研究的目的是在农田尺度上测量受历史AFFF使用影响的混凝土垫块降雨径流中关键PFAS的释放。在5 m2 （1 ×5 m）样地连续3天进行降雨模拟。每2 分钟收集一次径流水，并分析与AFFF相关的5种PFAS。雨水径流试验后，在小区内采集混凝土表面试样。全氟辛烷磺酸（PFOS）在混凝土中的浓度最高（高达~ 4000 μg kg−1），径流水中的浓度最高（高达500 μg L−1），其次是6:2氟端聚体磺酸（6:2 FTS）。径流水中PFAS浓度在第一个样品中较高，在每个降雨模拟的连续样品中依次下降。据估计，每次降雨事件中，混凝土表面总PFAS质量对径流样品的贡献百分比从0.006 % （PFOS）到0.031 % （PFHxA）不等。这表明受afff影响的混凝土中低但持续的PFAS浸出到径流水中。我们的研究结果证实，受AFFF遗留使用影响的混凝土可能是径流水中PFAS的次要来源，并强调了实验室和现场尺度降雨模拟之间的一些异同。

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引用次数: 0

Effect of triclosan on phosphate solubilising bacteria in mangrove ecosystem: In-vitro and In-vivo 三氯生对红树林生态系统中磷酸盐增溶菌的体外和体内影响

IF 6.6 Q1 ENGINEERING, ENVIRONMENTAL

Journal of hazardous materials letters

Pub Date : 2024-11-19 DOI: 10.1016/j.hazl.2024.100136

R.K. Dash , K. Kumar , S.P. Shukla , S. Kumar , S. Kumar H , S. Karmakar , T. Paul

Triclosan (TCS) is a widely used biocide found in medicinal, household, and personal care products, frequently detected in various environmental matrices, posing significant threats to microbial communities and overall ecosystem functioning. This study evaluates the in vivo and in vitro effects of triclosan (TCS) on phosphate-solubilising bacteria (PSB) in mangrove ecosystems. Two experimental approaches were employed: a microcosm (in vivo) study and a laboratory (in vitro) analysis. Five isolated PSB strains—Sphingomonas paucimobilis, Rhizobium radiobacter, Serratia ficaria, Klebsiella oxytoca, and Klebsiella pneumoniae—were selected from the mangrove ecosystem for investigation. The minimum inhibitory concentration (MIC) results revealed that Klebsiella pneumoniae exhibited the highest resistance to TCS among the tested strains. In vivo experiments demonstrated a significant reduction in soil-available phosphorus and enzymatic activities, including acid and alkaline phosphatase, dehydrogenase, and fluorescein diacetate (FDA) activity, in TCS-exposed samples throughout the exposure period. In vitro results showed that phosphate solubilisation decreased significantly with increasing TCS concentrations in all strains except Klebsiella pneumoniae. Overall, TCS effectively inhibited the growth of PSB in mangrove ecosystems. This study is the first to report the impact of TCS on PSB in mangroves and provides valuable data for future research on microbial communities in such environments.

三氯生（TCS）是一种广泛应用于医药、家庭和个人护理产品中的杀菌剂，经常在各种环境矩阵中检测到，对微生物群落和整体生态系统功能构成重大威胁。本研究评估了三氯生（TCS）对红树林生态系统中磷酸盐溶解菌（PSB）的体内和体外影响。采用两种实验方法：微观（体内）研究和实验室（体外）分析。从红树林生态系统中分离出少动鞘氨单胞菌、放射根瘤菌、沙雷氏菌、氧化克雷伯菌和肺炎克雷伯菌5株PSB进行研究。最低抑菌浓度（MIC）结果显示肺炎克雷伯菌对TCS的耐药性最高。体内实验表明，在整个暴露期间，暴露于tcs的样品中土壤有效磷和酶活性（包括酸性和碱性磷酸酶、脱氢酶和双乙酸荧光素（FDA）活性）显著降低。体外实验结果显示，除肺炎克雷伯菌外，所有菌株的磷酸盐增溶作用均随TCS浓度的增加而显著降低。总体而言，TCS有效抑制了红树林生态系统中PSB的生长。本研究首次报道了TCS对红树林PSB的影响，为今后研究此类环境下的微生物群落提供了有价值的数据。

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引用次数: 0