Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-418-421
P. Tkachenko, K. Lokes, V. V. Bondarenko, S. Bilokon, O. Ivanytska, K. Rezvina, I. O. Ivanicky
{"title":"CLINICAL CHARACTERISTIC OF DIFFERENT TYPES OF CONSERVATIVE TREATMENT OS PATHOLOGICAL SCARS OF HEAD AND NECK","authors":"P. Tkachenko, K. Lokes, V. V. Bondarenko, S. Bilokon, O. Ivanytska, K. Rezvina, I. O. Ivanicky","doi":"10.29254/2077-4214-2023-1-168-418-421","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-418-421","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"130 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73587534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-200-206
S. Lytovchenko, O. Pelypenko, S. Malyk, O. I. Berezan, I. O. Liublinska
{"title":"THE ROLE OF SCREENINGS IN PEDIATRIC ORTHOPEDIC AND DENTAL PATHOLOGY DIAGNOSTICS","authors":"S. Lytovchenko, O. Pelypenko, S. Malyk, O. I. Berezan, I. O. Liublinska","doi":"10.29254/2077-4214-2023-1-168-200-206","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-200-206","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77490963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2022-4-167-160-166
Y. Karachentsev, V. Dubovyk, I. Gopkalova, V. Khaziev, M. Sazonov, L. Gerasimenko
{"title":"LONG-TERM RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH PRIMARY HYPERPARATHYROIDISM","authors":"Y. Karachentsev, V. Dubovyk, I. Gopkalova, V. Khaziev, M. Sazonov, L. Gerasimenko","doi":"10.29254/2077-4214-2022-4-167-160-166","DOIUrl":"https://doi.org/10.29254/2077-4214-2022-4-167-160-166","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87627661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-45-46
А. М. Громова, Ніна Іванівна Мітюніна, Н. О. Прилуцька, Ольга Леонідівна Громова, О. М. Кетова, Ю. А. Орлова
{"title":"ОСОБЛИВОСТІ ПІДГОТОВКИ АКУШЕРІВ-ГІНЕКОЛОГІВ ЗГІДНО ВИМОГ ЧАСУ","authors":"А. М. Громова, Ніна Іванівна Мітюніна, Н. О. Прилуцька, Ольга Леонідівна Громова, О. М. Кетова, Ю. А. Орлова","doi":"10.29254/2523-4110-2023-2-169/addition-45-46","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-45-46","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"97 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85313623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2523-4110-2023-2-169/addition-6
Розвитку Сучасної, Медицини І Стоматології
Introduction. Taste plays an essential role in human life. Taste is not only a protective mechanism we recognize the suitability of products for consumption but also a way to get positive emotions from delicious food. Every day, a person consumes food products that contain food additives [1-3]. Food additives are a group of natural or synthetic substances added to food raw materials, finished products and semi-finished products to give them specific taste properties, a good appearance and increase the duration of storage. The most common additives we study are monosodium glutamate (E621), sodium nitrite (E250) and Ponceau 4R (E124). Unfortunately, these additives harm human health and cause serious diseases. Particular attention should be paid to the effect of these supplements on the adrenal glands, as they can cause disruption of their function and cause oncological diseases. Aim of the study. To determine the morphometric changes in the wall thickness of the arterioles of the medulla of the adrenal glands of rats under the influence of a food additive complex. Main part. An experimental study was conducted on 80 rats. The control group of rats consumed drinking water and saline orally. Rats from the experimental group were given to drink a 10% solution of sodium nitrite (E 250); monosodium glutamate (E621) was administered at a dose of 20 mg/kg in 0.5 ml of distilled water; Ponceau 4R – at a dose of 5 mg/kg in 0.5 ml of distilled water once a day orally. Dosages of food additives were two times lower than the permissible norm in food products. After 1, 4, 8, 12 and 16 weeks, rats were removed from the experiment by decapitation under ether anesthesia. Then, the fragments fixed in formalin were sealed in paraffin. Subsequently, the sections stained with hematoxylin and eosin were examined using a Biorex light microscope with a DSM 900 digital photomicroscope. In order to obtain semi-thin sections, the studied material was fixed in glutaraldehyde and sealed in EPON-812. Ready sections were stained with toluidine blue. The morphometric method determined the wall thickness of the medulla adrenal glands' arteriolas. Data processing was carried out using the Excel program. During the morphometric study, it was found that the hemomicrocirculatory channel (HMCB) of the adrenal glands of rats is well-developed and multi-component. After modelling the experimental effect of food additives, we discovered the regular reactions of the vessels of the medulla and their structural rearrangement. During the morphometric study of the average total wall thickness of arterioles of the medulla of the control group, it was established that the average total wall thickness of arterioles was (1.54±0.01) μm. After animals use food additives, morphometric indicators change significantly. After the 1st week, the indicator was (1.51±0.03) μm, 1.95% less than the control value. In the 4th week, this indicator was (1.58±0.04) μm, 2.59% more than the control value. After th
{"title":"MORPHOMETRIC CHANGES IN THE WALL THICKNESS OF MEDULLAS ARTERIOLES OF THE RATS ADRENAL GLANDS AFTER THE INFLUENCE OF A FOOD ADDITIVE COMPLEX","authors":"Розвитку Сучасної, Медицини І Стоматології","doi":"10.29254/2523-4110-2023-2-169/addition-6","DOIUrl":"https://doi.org/10.29254/2523-4110-2023-2-169/addition-6","url":null,"abstract":"Introduction. Taste plays an essential role in human life. Taste is not only a protective mechanism we recognize the suitability of products for consumption but also a way to get positive emotions from delicious food. Every day, a person consumes food products that contain food additives [1-3]. Food additives are a group of natural or synthetic substances added to food raw materials, finished products and semi-finished products to give them specific taste properties, a good appearance and increase the duration of storage. The most common additives we study are monosodium glutamate (E621), sodium nitrite (E250) and Ponceau 4R (E124). Unfortunately, these additives harm human health and cause serious diseases. Particular attention should be paid to the effect of these supplements on the adrenal glands, as they can cause disruption of their function and cause oncological diseases. Aim of the study. To determine the morphometric changes in the wall thickness of the arterioles of the medulla of the adrenal glands of rats under the influence of a food additive complex. Main part. An experimental study was conducted on 80 rats. The control group of rats consumed drinking water and saline orally. Rats from the experimental group were given to drink a 10% solution of sodium nitrite (E 250); monosodium glutamate (E621) was administered at a dose of 20 mg/kg in 0.5 ml of distilled water; Ponceau 4R – at a dose of 5 mg/kg in 0.5 ml of distilled water once a day orally. Dosages of food additives were two times lower than the permissible norm in food products. After 1, 4, 8, 12 and 16 weeks, rats were removed from the experiment by decapitation under ether anesthesia. Then, the fragments fixed in formalin were sealed in paraffin. Subsequently, the sections stained with hematoxylin and eosin were examined using a Biorex light microscope with a DSM 900 digital photomicroscope. In order to obtain semi-thin sections, the studied material was fixed in glutaraldehyde and sealed in EPON-812. Ready sections were stained with toluidine blue. The morphometric method determined the wall thickness of the medulla adrenal glands' arteriolas. Data processing was carried out using the Excel program. During the morphometric study, it was found that the hemomicrocirculatory channel (HMCB) of the adrenal glands of rats is well-developed and multi-component. After modelling the experimental effect of food additives, we discovered the regular reactions of the vessels of the medulla and their structural rearrangement. During the morphometric study of the average total wall thickness of arterioles of the medulla of the control group, it was established that the average total wall thickness of arterioles was (1.54±0.01) μm. After animals use food additives, morphometric indicators change significantly. After the 1st week, the indicator was (1.51±0.03) μm, 1.95% less than the control value. In the 4th week, this indicator was (1.58±0.04) μm, 2.59% more than the control value. After th","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85498971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-240-245
V. Havryliev, O. P. Bukhanchenko, I. Boiko, I. Yatsenko
{"title":"PSYCHOLOGICAL AND PEDAGOGICAL ASPECTS OF PLANNING THE EDUCATIONAL PROCESS IN A HIGHER EDUCATIONAL INSTITUTION IN RELATION TO AGE","authors":"V. Havryliev, O. P. Bukhanchenko, I. Boiko, I. Yatsenko","doi":"10.29254/2077-4214-2023-1-168-240-245","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-240-245","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90292500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-1-168-17-29
U. А. Kostrikova, L. O. Myakinkova, G. L. Pustovoit, T. I. Yarmola
{"title":"VASCULAR DEPRESSION AND CARDIOVASCULAR COMPLICATIONS OF TYPE 2 DIABETES","authors":"U. А. Kostrikova, L. O. Myakinkova, G. L. Pustovoit, T. I. Yarmola","doi":"10.29254/2077-4214-2023-1-168-17-29","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-1-168-17-29","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"201 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91466170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-2-169-148-158
V. MartіianovaYu., Martіianova Yuliya, Volodymyrivna Мартіянова, Юлія Володимирівна
of a pesticide
杀虫剂
{"title":"RISK-ORIENTED APPROACHES TO OPTIMIZE THE VOLUME OF EXPERIMENTAL STUDIES PESTICIDES' HYGIENE STANDARD IN SOIL (first message)","authors":"V. MartіianovaYu., Martіianova Yuliya, Volodymyrivna Мартіянова, Юлія Володимирівна","doi":"10.29254/2077-4214-2023-2-169-148-158","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-148-158","url":null,"abstract":"of a pesticide","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91473369","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2023-2-169-281-296
Malevych Nаtaliya Mykhaylivna, Karpinsky M. Yu, Karpinsky Mykhaylo, Yuriyovych Карпінський, Михайло Юрійович
. Worldwide, acute generalized peritonitis (AGP) is a common medical and surgical emergency and a major cause of mortality. Despite the obvious successes of diagnostics, the use of various antibacterial drugs of the new generation, the introduction of modern methods of minimally invasive treatment, the mortality rate in AGP ranges from 12.5% to 39.2%. The basis of the severe course and high mortality rates in acute peritonitis is often concomitant pathology, among which obesity is present in 7.5% to 14.0%. Aim – to study the state of the indicators of the nitric oxide system in the body of experimental animals with simulated AGP against the background of obesity and compare them with groups of obese animals and with animals with AGP.
{"title":"FINITE ELEMENT ANALYSIS OF THORACOLUMBAR JUNCTION TRANSPEDICULAR FIXATION VARIANTS AFTER RESECTION OF THE TH12 VERTEBRA WHILE FORWARD BENDING","authors":"Malevych Nаtaliya Mykhaylivna, Karpinsky M. Yu, Karpinsky Mykhaylo, Yuriyovych Карпінський, Михайло Юрійович","doi":"10.29254/2077-4214-2023-2-169-281-296","DOIUrl":"https://doi.org/10.29254/2077-4214-2023-2-169-281-296","url":null,"abstract":". Worldwide, acute generalized peritonitis (AGP) is a common medical and surgical emergency and a major cause of mortality. Despite the obvious successes of diagnostics, the use of various antibacterial drugs of the new generation, the introduction of modern methods of minimally invasive treatment, the mortality rate in AGP ranges from 12.5% to 39.2%. The basis of the severe course and high mortality rates in acute peritonitis is often concomitant pathology, among which obesity is present in 7.5% to 14.0%. Aim – to study the state of the indicators of the nitric oxide system in the body of experimental animals with simulated AGP against the background of obesity and compare them with groups of obese animals and with animals with AGP.","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"1905 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91515786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.29254/2077-4214-2022-4-167-263-268
S. Kolupayev, M. Lisova, M. Y. Cherniak, I. Bielievtsova
{"title":"IMPLEMENTATION OF THE PRINCIPLE OF PARTICIPATION IN CHOOSING A TREATMENT METHOD FOR PATIENTS WITH UROLITHIASIS","authors":"S. Kolupayev, M. Lisova, M. Y. Cherniak, I. Bielievtsova","doi":"10.29254/2077-4214-2022-4-167-263-268","DOIUrl":"https://doi.org/10.29254/2077-4214-2022-4-167-263-268","url":null,"abstract":"","PeriodicalId":9360,"journal":{"name":"Bulletin of Problems Biology and Medicine","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88684505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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