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Mucocutaneous leishmaniasis with upper airway involvement: A report of three cases 累及上呼吸道的皮肤粘膜利什曼病:附3例报告。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512276
Jaume Fiol Roig , Amaya Roldan Fidalgo , Fabián García Velasco , Meritxell Tomás Fernández , Daniela Mendizábal Cajal
Mucocutaneous leishmaniasis (MCL) is a rare and challenging clinical presentation of tegumentary leishmaniasis, primarily affecting the mucosal surfaces of the upper airway. It is often misdiagnosed due to its non-specific symptoms, which can mimic inflammatory, infectious, or neoplastic conditions. This study reports three autochthonous cases of MCL diagnosed between 2023 and 2024. The patients presented chronic symptoms such as dysphagia, odynophagia, lip edema, and ulcerative mucosal lesions. Diagnosis was established through mucosal biopsies, revealing intracellular Leishmania amastigotes via histopathological examination. Treatment varied across the cases and included liposomal Amphotericin B, Meglumine Antimoniate, and Miltefosine, reflecting the complexity of managing MCL. All patients achieved complete clinical remission after individualized therapeutic regimens and careful follow-up. These cases emphasize the importance of considering MCL in the differential diagnosis of persistent upper airway lesions in endemic regions. Early and accurate diagnosis, coupled with tailored treatment strategies, is essential for preventing disease progression and achieving successful clinical outcomes. Furthermore, these findings underscore the need for heightened clinical awareness and multidisciplinary collaboration in managing this rare but significant disease presentation.
粘膜皮肤利什曼病(MCL)是一种罕见且具有挑战性的被膜利什曼病的临床表现,主要影响上呼吸道的粘膜表面。它经常被误诊,因为它的非特异性症状,可以模仿炎症,感染,或肿瘤条件。本研究报告了2023年至2024年间诊断出的三例MCL本地病例。患者表现为吞咽困难、吞咽困难、唇部水肿、溃疡性粘膜病变等慢性症状。通过粘膜活检确定诊断,通过组织病理学检查显示细胞内利什曼原虫。治疗方法因病例而异,包括两性霉素B脂质体、锑酸甲氨苄胺和米特福辛,这反映了治疗MCL的复杂性。经过个体化的治疗方案和仔细的随访,所有患者均获得完全的临床缓解。这些病例强调了在流行地区持续性上呼吸道病变的鉴别诊断中考虑MCL的重要性。早期和准确的诊断,加上量身定制的治疗策略,对于预防疾病进展和取得成功的临床结果至关重要。此外,这些发现强调需要提高临床意识和多学科合作来管理这种罕见但重要的疾病表现。
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引用次数: 0
Diagnostic accuracy of the head pitch test in benign paroxysmal positional vertigo 头距试验诊断良性阵发性位置性眩晕的准确性。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512288
Mayada Elsherif , Alia Elkaraksy , Dalia Eldeeb , Mirhan Eldeeb

Introduction and objectives

The diagnostic accuracy and reliability of the head pitch test in differentiating between different types of BPPV require further investigation. Studying the diagnostic accuracy of the head pitch test in BPPV diagnosis can aid in the development of targeted management strategies for patients presenting with BPPV.

Methods

All patients who complained of positional vertigo for seconds underwent complete videonystagmography test using ICS Chartr 200 VNG/ENG system (Otometrics, Denmark) including : spontaneous nystagmus, complete occulomotor test battery, then the head pitch test was performed in two positions: first the patient’s head was bent 90 degrees forwards, then 60 degrees backwards for approximately 1 min each. If nystagmus was observed, its direction was recorded.1 All patients then underwent gold standard tests for positional vertigo including both Dix-Hallpike maneuver and the supine roll tests.

Results

The sensitivity (true positive cases) was defined as the head pitch (HPT) test being positive and showing the correct nystagmus for different categories of BPPV. The sensitivity of the experimental HPT was compared to the gold standard tests (100% sensitive) for diagnosis of different categories of vertical canal and lateral canal BPPV. It was highest (100%) for Lateral Cupulolithiasis patients (n = 12) and Anterior canal Canalithiasis (n = 3) and lowest (68%) for Typical Posterior Canalithiasis patients (n = 68).

Conclusion

This study supports the addition of the head pitch test in the routine assessment of patients with positional vertigo. As it could shorten the examination time and decrease the repositioning maneuvers which may cause severe autonomic symptoms.
前言和目的:颅距试验在区分不同类型BPPV诊断中的准确性和可靠性有待进一步研究。方法:所有体位性眩晕患者均采用ICS Chartr 200 VNG/ENG系统(Otometrics,丹麦)进行完整的视震仪测试,包括自发性眼球震颤、完全眼动测试电池,然后在两个体位进行头距测试。首先患者头部向前弯曲90度,然后向后弯曲60度,每次约1分钟。如果观察到眼球震颤,则记录其方向1。所有患者随后接受体位性眩晕的金标准测试,包括Dix-Hallpike手法和仰卧翻滚测试。结果:敏感度(真阳性病例)定义为头距(HPT)试验阳性,并正确显示不同类型BPPV的眼球震颤。将实验HPT与金标准试验(100%敏感性)对不同类型的垂直管和侧管BPPV的诊断进行比较。侧管结石患者(n = 12)和前管结石患者(n = 3)发生率最高(100%),典型后管结石患者(n = 68)发生率最低(68%)。结论:本研究支持在体位性眩晕患者的常规评估中增加头距试验。因为它可以缩短检查时间,减少可能引起严重自主神经症状的重新定位动作。
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引用次数: 0
Standardisation of sinonasal anatomical terminology in Spanish: An expert consensus 西班牙语鼻部解剖学术语的标准化:专家共识。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512275
Juan Ramón Gras-Cabrerizo , Juan Carlos Villatoro-Sologaistoa , Maria Casasayas-Plass , María Martel-Martín , Carolina Alfonso-Carrillo , Miguel Armengot-Carceller , María Sandra Domínguez-Sosa , Rafael Fernandez-Liesa , Ainhoa García-Lliberós , María Gil-Melcón , Xavier González-Compta , Fernando López-Álvarez , Mauricio López-Chacón , David Lobo-Duro , Nieves Mata-Castro , Irene Monjas-Cánovas , Ramon Moreno-Luna , Laura Pardo-Muñoz , Mayte Pinilla-Urraca , Alfonso Santamaría-Gadea , Isam Alobid

Introduction

Advances in endonasal endoscopic surgery have highlighted the need to unify and adapt sinonasal anatomical terminology. This study aims to translate and validate the anatomical terms proposed by the European Rhinologic Society into Spanish, in order to facilitate their use and dissemination.

Methods

A Delphi methodology was employed, involving 24 nationally recognised rhinologists with extensive experience in endoscopic surgery. In the first round, Spanish equivalents were proposed for the 121 concepts included in the EPOS (European Position Paper on the Anatomical Terminology) supplement. In the second round, each participant selected a single preferred term among the most voted options. Finally, a panel of seven national experts reviewed and approved the definitive terms, including additional concepts not previously addressed in reference documents.

Results

In 61% (73/121) of the concepts, the expert panel ratified the term most voted by the group of rhinologists. In 31% (38/121), the most voted term was modified, and in 8% (10/121), a final decision was made in the event of a tie. The use of eponyms and latinisms was avoided whenever possible. The terminology selected aimed to accurately reflect the corresponding anatomical concepts. Moreover, relevant terms not included in the EPOS consensus documents or the Anatomical Terminology were incorporated.

Conclusion

The adaptation and validation of sinonasal anatomical terminology into Spanish enhances international communication and contributes to improving clinical practice in rhinology.
引言:鼻内窥镜手术的进展强调了统一和适应鼻解剖术语的必要性。本研究旨在将欧洲鼻学会提出的解剖学术语翻译并验证为西班牙语,以促进其使用和传播。方法:采用德尔菲法,包括24名在内窥镜手术方面经验丰富的国家认可的鼻内科医生。在第一轮中,为EPOS(欧洲解剖术语立场文件)补充中包含的121个概念提出了西班牙语对等物。在第二轮中,每位参与者从得票最多的选项中选择一个首选词。最后,一个由七名国家专家组成的小组审查并核可了确定用语,包括参考文件以前未涉及的其他概念。结果:在61%(73/121)的概念中,专家小组批准了由鼻内科医生群体投票最多的术语。在31%(38/121)中,投票最多的条款被修改,在8%(10/121)中,如果出现平局,则做出最终决定。只要可能,就尽量避免使用缩略词和拉丁词。所选择的术语旨在准确反映相应的解剖学概念。此外,纳入了EPOS共识文件或解剖学术语中未包含的相关术语。结论:鼻窦解剖术语的西班牙语改编和验证促进了国际交流,有助于提高鼻科临床实践水平。
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引用次数: 0
Malignant sinonasal paraganglioma: A major clinical and histopathological challenge in a rare entity 恶性鼻窦副神经节瘤:一个罕见实体的主要临床和组织病理学挑战。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512292
Ángel Ángel de Miguel , Atilio Navarro , Moisés Sánchez Pardo , Ainhoa García-Lliberós
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引用次数: 0
Spanish multidisciplinary Consensus on the diagnosis and management of laryngopharyngeal reflux (ReFaL Consensus) 西班牙关于喉部反流诊断和治疗的多学科共识(ReFaL共识)。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512309
María Agustina Sevilla García , Carlos Miguel Chiesa-Estomba , Luz Barona-Lleó , Ángel Álvarez Sánchez , Carlos Martín de Argila

Introduction

Laryngopharyngeal reflux (LPR) represents a diagnostic and therapeutic challenge due to the nonspecific nature of its clinical manifestations and the absence of objective biomarkers. The aim of this work is to establish a national consensus on its definition, diagnosis, and treatment through a modified Delphi methodology that integrates the perspectives of otolaryngologists (ENT) and gastroenterologists (GI).

Materials and methods

A scientific committee composed of three ENTs and two GIs developed 117 items distributed across seven thematic sections. The Delphi process involved 73 panellists in the first round, of whom 65 (89%) completed both rounds of voting. Participants were representative of the Spanish autonomous communities, with an average of 17 years of clinical experience and a multidisciplinary profile (63.1% ENT; 36.9% GI).

Results

After two rounds of voting, positive consensus was reached on 76 items (64.9%), distributed as follows: 14 on definition and pathophysiology; 12 on symptoms and pharyngeal findings; 2 on associations with other ENT diseases; 10 on diagnostic methods; 3 on validated questionnaires; 15 on treatment and recommendations; and 11 on clinical follow-up.

Conclusion

The results of the consensus reflect the suitability and effectiveness of the Delphi methodology used to create a consensus document on the definition, presentation, diagnosis, and management of a condition that until now has been poorly defined, such as LPR. The aim is to support specialists in their daily clinical practice, and unlike previous efforts, it has succeeded in unifying within a single document the criteria of the two specialties most involved in managing these patients.
简介:喉咽反流(LPR)由于其临床表现的非特异性和缺乏客观的生物标志物,代表了诊断和治疗的挑战。这项工作的目的是通过改进的德尔菲方法,整合耳鼻喉科(ENT)和胃肠病学(GI)的观点,就其定义、诊断和治疗建立全国共识。材料和方法:一个由三名门诊部和两名门诊部组成的科学委员会编制了117个项目,分布在七个专题部分。德尔菲过程在第一轮中涉及73名小组成员,其中65人(89%)完成了两轮投票。参与者是西班牙自治区的代表,平均具有17年的临床经验和多学科概况(63.1%的耳鼻喉科;36.9%的胃肠道)。结果:经过两轮投票,76项(64.9%)获得肯定意见,分布如下:定义和病理生理14项;12 .症状和咽部表现;2 .与其他耳鼻喉科疾病的关系;10 .诊断方法;3 .有效问卷;15 .治疗和建议;11人进行临床随访。结论:共识的结果反映了德尔菲方法的适用性和有效性,该方法用于创建共识文件,以定义,表现,诊断和管理直到现在还没有明确定义的疾病,如LPR。目的是支持专家在日常临床实践中,与以前的努力不同,它成功地将管理这些患者最涉及的两个专业的标准统一在一个文件中。
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引用次数: 0
Impact of cochlear implants on cognitive performance during aging 人工耳蜗对老年认知能力的影响。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512289
Fatima Ezzahra Rizkou , Youssef Lakhdar , Omar Oulghoul , Mohammed Chehbouni , Othmane Benhoummad , Youssef Rochdi , Abdelaziz Raji

Objective

This study evaluates the impact of cochlear implantation on cognitive function in older adults, focusing on executive function, processing speed, and memory.

Methods

A prospective observational study was conducted on 15 older adults (mean age: 72.4 years) who underwent cochlear implantation at the ENT and Head and Neck Surgery Department. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and the Trail Making Test (TMT-A and TMT-B) pre- and post-implantation (6 and 12 months). Results were compared using statistical analyses, and correlations between cognitive improvement and speech perception outcomes were examined.

Results

Cognitive function significantly improved post-implantation, with MMSE scores increasing from 22.93 ± 3.2 at baseline to 24.6 ± 2.9 at 12 months (p < 0.05). TMT-A and TMT-B scores also improved significantly (p < 0.05), indicating enhanced executive function and processing speed. A moderate correlation (r = 0.52, p = 0.04) was observed between cognitive improvement and speech perception.

Conclusion

These findings support the hypothesis that cochlear implantation in older adults positively impacts cognitive function. This study adds to the growing body of evidence suggesting that auditory rehabilitation may help mitigate cognitive decline in aging populations.
目的:本研究评估人工耳蜗植入对老年人认知功能的影响,重点关注执行功能、处理速度和记忆。方法:对在耳鼻喉科和头颈外科行人工耳蜗植入术的15例老年人(平均年龄72.4岁)进行前瞻性观察研究。在植入前后(6个月和12个月)采用简易精神状态检查(MMSE)和造径测试(TMT-A和TMT-B)评估认知功能。使用统计分析对结果进行比较,并检查认知改善与言语感知结果之间的相关性。结果:耳蜗植入后认知功能明显改善,MMSE评分从基线时的22.93±3.2提高到12个月时的24.6±2.9 (p)。结论:这些发现支持了老年人耳蜗植入对认知功能有积极影响的假设。这项研究增加了越来越多的证据,表明听觉康复可能有助于减轻老年人的认知能力下降。
{"title":"Impact of cochlear implants on cognitive performance during aging","authors":"Fatima Ezzahra Rizkou ,&nbsp;Youssef Lakhdar ,&nbsp;Omar Oulghoul ,&nbsp;Mohammed Chehbouni ,&nbsp;Othmane Benhoummad ,&nbsp;Youssef Rochdi ,&nbsp;Abdelaziz Raji","doi":"10.1016/j.otoeng.2025.512289","DOIUrl":"10.1016/j.otoeng.2025.512289","url":null,"abstract":"<div><h3>Objective</h3><div>This study evaluates the impact of cochlear implantation on cognitive function in older adults, focusing on executive function, processing speed, and memory.</div></div><div><h3>Methods</h3><div>A prospective observational study was conducted on 15 older adults (mean age: 72.4 years) who underwent cochlear implantation at the ENT and Head and Neck Surgery Department. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and the Trail Making Test (TMT-A and TMT-B) pre- and post-implantation (6 and 12 months). Results were compared using statistical analyses, and correlations between cognitive improvement and speech perception outcomes were examined.</div></div><div><h3>Results</h3><div>Cognitive function significantly improved post-implantation, with MMSE scores increasing from 22.93 ± 3.2 at baseline to 24.6 ± 2.9 at 12 months (<em>p &lt; 0.05</em>). TMT-A and TMT-B scores also improved significantly (<em>p &lt; 0.05</em>), indicating enhanced executive function and processing speed. A moderate correlation (<em>r = 0.52, p = 0.04</em>) was observed between cognitive improvement and speech perception.</div></div><div><h3>Conclusion</h3><div>These findings support the hypothesis that cochlear implantation in older adults positively impacts cognitive function. This study adds to the growing body of evidence suggesting that auditory rehabilitation may help mitigate cognitive decline in aging populations.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"77 1","pages":"Article 512289"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coblation versus suction Diathermy in Endoscopic Pediatric Adenoidectomy: Randomized clinical trial 内镜下小儿腺样体切除术中消融与吸吸透热:随机临床试验。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512287
Abobakr Mohammed Elbakry , Ahmed Nabil Selim , Alaa Abdelwahab Eldarawy , Abdallah Mahmoud Gad

Objectives

The aim of the study is comparing endoscopic coblation adenoidectomy and suction diathermy in terms of surgical duration, intraoperative blood loss, and postoperative complications such as foul odor, neck pain, and secondary bleeding, as well as patient recovery.

Patients and methods

Prospective randomized double blinded controlled trial involving 210 patients who presented with adenoid hypertrophy. Randomization was done in two groups group A including 105 patients who underwent endoscopic adenoidectomy by suction diathermy, Group B including 105 patients who underwent endoscopic adenoidectomy by coblation technique.
Patients were compared regarding intraoperative blood loss and operative time and postoperative bleeding, postoperative neck pain, and halitosis.

Results

When comparing the two groups, Group B had notably longer surgeries but experienced less pain after the operation, recovered more quickly, and had a lower chance of bad breath. There was no significant difference between both the groups regarding intraoperative blood loss.

Conclusion

Both techniques are effective in management of adenoid hypertrophy, but results showed endoscopic adenoidectomy with coblation is favored over suction diathermy due to better postoperative outcomes.
目的:本研究的目的是比较内镜下消融腺样体切除术和吸痰透热术在手术时间、术中出血量、术后并发症(如恶臭、颈部疼痛、继发性出血)和患者恢复方面的差异。患者和方法:前瞻性随机双盲对照试验,纳入210例腺样体肥大患者。随机分为两组,A组105例采用吸热法进行内窥镜腺样体切除术,B组105例采用cocoation技术进行内窥镜腺样体切除术。比较患者术中出血量、手术时间、术后出血、术后颈部疼痛和口臭。结果:两组比较,B组手术时间明显延长,但术后疼痛较少,恢复较快,口臭发生率较低。结论:两种技术都是治疗腺样体肥大的有效方法,但结果显示,内镜下腺样体切除术合并Coblation优于吸痰透热,因为内镜下评估和术后效果更好。
{"title":"Coblation versus suction Diathermy in Endoscopic Pediatric Adenoidectomy: Randomized clinical trial","authors":"Abobakr Mohammed Elbakry ,&nbsp;Ahmed Nabil Selim ,&nbsp;Alaa Abdelwahab Eldarawy ,&nbsp;Abdallah Mahmoud Gad","doi":"10.1016/j.otoeng.2025.512287","DOIUrl":"10.1016/j.otoeng.2025.512287","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of the study is comparing endoscopic coblation adenoidectomy and suction diathermy in terms of surgical duration, intraoperative blood loss, and postoperative complications such as foul odor, neck pain, and secondary bleeding, as well as patient recovery.</div></div><div><h3>Patients and methods</h3><div>Prospective randomized double blinded controlled trial involving 210 patients who presented with adenoid hypertrophy. Randomization was done in two groups group A including 105 patients who underwent endoscopic adenoidectomy by suction diathermy, Group B including 105 patients who underwent endoscopic adenoidectomy by coblation technique.</div><div>Patients were compared regarding intraoperative blood loss and operative time and postoperative bleeding, postoperative neck pain, and halitosis.</div></div><div><h3>Results</h3><div>When comparing the two groups, Group B had notably longer surgeries but experienced less pain after the operation, recovered more quickly, and had a lower chance of bad breath. There was no significant difference between both the groups regarding intraoperative blood loss.</div></div><div><h3>Conclusion</h3><div>Both techniques are effective in management of adenoid hypertrophy, but results showed endoscopic adenoidectomy with coblation is favored over suction diathermy due to better postoperative outcomes.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"77 1","pages":"Article 512287"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145240357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From the operating theatre to the office: Functional outcomes, tolerability, and cost-effectiveness of the blue laser in benign laryngeal surgery 从手术室到门诊部:蓝色激光良性喉部手术的功能结果、耐受性和成本效益。
Pub Date : 2026-01-01 DOI: 10.1016/j.otoeng.2025.512293
Eduardo Lehrer , Tomeu Alberto , Ada Cabero , Mónica Egea , Marina Paredes , Sara Jubés , Isabel Vilaseca

Background and objectives

The 445 nm blue laser has expanded therapeutic possibilities in the office. However, comparative studies with laser surgery in the operating theatre are scarce. The present study aims to analyse both techniques applied to the treatment of benign laryngeal lesions in terms of efficacy, tolerability, and efficiency.

Materials and methods

Prospective, non-randomised observational study of 93 consecutive patients with benign laryngeal lesions treated in the office (TNFLS) or in the operating theatre using transoral blue laser microsurgery (TOBLM), (48 TNFLS, 38 TOBLM, 7 combined cases). Vocal outcomes were assessed using the abbreviated vocal handicap index (VHI-10), a visual analogue scale (VAS) and the acoustic voice quality index (AVQI) obtained from acoustic analysis, as well as the tolerability and efficiency of the procedures. The variables were evaluated before and 3 months after surgery.

Results

Both groups showed improvements at 3 months postoperatively in VHI-10, VAS, and AVQI, with no differences between techniques. TNFLS had a high tolerability rate (95.4%) and was significantly more cost-effective, with a cost-per-point of improvement in the VHI-10 of €86.30 vs. €200.42.

Conclusions

TNFLS with blue laser is an effective, well-tolerated, and cost-effective alternative to conventional surgery for benign laryngeal lesions. These results support its implementation in dynamic healthcare settings that prioritize efficiency.
背景和目的:445纳米蓝色激光扩大了门诊治疗的可能性。然而,与激光手术在手术室的比较研究很少。本研究旨在分析两种技术在治疗良性喉部病变方面的疗效、耐受性和效率。材料与方法:前瞻性、非随机观察性研究,对93例连续在门诊(TNFLS)或在手术室接受经口蓝色激光显微手术(TOBLM)治疗的喉良性病变患者进行观察,(TNFLS 48例,TOBLM 38例,合并7例)。通过缩短声带障碍指数(VHI-10)、视觉模拟量表(VAS)和声学分析获得的声学语音质量指数(AVQI)以及手术的耐受性和效率来评估声带结果。在手术前和手术后3个月评估这些变量。结果:两组术后3个月VHI-10、VAS和AVQI均有改善,两种技术间无差异。TNFLS具有较高的耐受性(95.4%),并且显著更具成本效益,VHI-10的每点改善成本为86.30欧元,而VHI-10的每点改善成本为200.42欧元。结论:蓝色激光联合TNFLS治疗良性喉部病变是一种有效、耐受性良好、成本效益高的替代传统手术治疗方法。这些结果支持其在优先考虑效率的动态医疗保健环境中实施。
{"title":"From the operating theatre to the office: Functional outcomes, tolerability, and cost-effectiveness of the blue laser in benign laryngeal surgery","authors":"Eduardo Lehrer ,&nbsp;Tomeu Alberto ,&nbsp;Ada Cabero ,&nbsp;Mónica Egea ,&nbsp;Marina Paredes ,&nbsp;Sara Jubés ,&nbsp;Isabel Vilaseca","doi":"10.1016/j.otoeng.2025.512293","DOIUrl":"10.1016/j.otoeng.2025.512293","url":null,"abstract":"<div><h3>Background and objectives</h3><div>The 445 nm blue laser has expanded therapeutic possibilities in the office. However, comparative studies with laser surgery in the operating theatre are scarce. The present study aims to analyse both techniques applied to the treatment of benign laryngeal lesions in terms of efficacy, tolerability, and efficiency.</div></div><div><h3>Materials and methods</h3><div>Prospective, non-randomised observational study of 93 consecutive patients with benign laryngeal lesions treated in the office (TNFLS) or in the operating theatre using transoral blue laser microsurgery (TOBLM), (48 TNFLS, 38 TOBLM, 7 combined cases). Vocal outcomes were assessed using the abbreviated vocal handicap index (VHI-10), a visual analogue scale (VAS) and the acoustic voice quality index (AVQI) obtained from acoustic analysis, as well as the tolerability and efficiency of the procedures. The variables were evaluated before and 3 months after surgery.</div></div><div><h3>Results</h3><div>Both groups showed improvements at 3 months postoperatively in VHI-10, VAS, and AVQI, with no differences between techniques. TNFLS had a high tolerability rate (95.4%) and was significantly more cost-effective, with a cost-per-point of improvement in the VHI-10 of €86.30 vs. €200.42.</div></div><div><h3>Conclusions</h3><div>TNFLS with blue laser is an effective, well-tolerated, and cost-effective alternative to conventional surgery for benign laryngeal lesions. These results support its implementation in dynamic healthcare settings that prioritize efficiency.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"77 1","pages":"Article 512293"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145472610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the impact of post-COVID-19 olfactory dysfunction on quality of life: Comparison of specific questionnaires. 评估covid -19后嗅觉功能障碍对生活质量的影响:具体问卷的比较
Pub Date : 2025-12-12 DOI: 10.1016/j.otoeng.2025.512312
Carlota Rovira-Martínez, Mariana Campos-Motamayor, Aina Sansa-Perna, Elios Yuste, Laura Gelabert, Josep de Haro-Licer, Alda Cardesín-Revilla, Miguel Caballero-Borrego

Background and objectives: Post-COVID-19 olfactory dysfunction persists in many patients and significantly affects quality of life. The primary objective was to evaluate olfactory function using psychophysical tests (BAST-24) and quality-of-life questionnaires. Secondary objectives included analysing correlations between questionnaires and the relationship between subjective and psychophysical measures.

Materials and methods: A prospective study was conducted including 86 adults with olfactory dysfunction ≥ 6 months after SARS-CoV-2 infection. Clinical and demographic data and scores from the Visual Analog Scale for smell (VAS-smell) and the SNOT-22, svQOD-NS, and QVOLF questionnaires were collected. Olfactory function was assessed using the BAST-24 (detection, identification, and olfactory memory). Descriptive statistics, Spearman's correlation coefficient, and the Mann-Whitney U test were used (p < 0.05).

Results: Mean age was 49 years (SD = 14); 76.7% were women. According to the VAS, 90.7% had hyposmia and 8.1% anosmia. Mean scores (SD) were: VAS 6 (2), SNOT-22 26 (20), svQOD-NS 4 (4), and QVOLF 127 (50), suggesting a moderate impact on quality of life. BAST-24 scores: detection 91% (22), identification 52% (25), and memory 35% (20). QVOLF and svQOD-NS showed a strong correlation (ρ = 0.797; p < 0.001), while SNOT-22 correlated moderately with both. No significant correlations were found between any questionnaire and BAST-24.

Conclusions: QVOLF and svQOD-NS questionnaires are more sensitive than SNOT-22 for assessing olfactory dysfunction. The lack of correlation with psychophysical tests highlights the need to combine both approaches fora comprehensive evaluation.

背景和目的:许多患者在covid -19后仍然存在嗅觉功能障碍,并显著影响生活质量。主要目的是通过心理物理测试(BAST-24)和生活质量问卷来评估嗅觉功能。次要目标包括分析问卷之间的相关性以及主观和心理物理测量之间的关系。材料和方法:对86例SARS-CoV-2感染后嗅觉功能障碍≥6个月的成人进行前瞻性研究。收集临床和人口统计数据以及嗅觉视觉模拟量表(VAS-smell)和SNOT-22、svQOD-NS和QVOLF问卷的得分。使用BAST-24(检测、识别和嗅觉记忆)评估嗅觉功能。采用描述性统计、Spearman相关系数和Mann-Whitney U检验(p)。结果:平均年龄为49岁(SD = 14);76.7%为女性。根据VAS, 90.7%的人有低嗅觉,8.1%的人有嗅觉缺失。平均评分(SD)为:VAS 6 (2), SNOT-22 26 (20), svQOD-NS 4 (4), QVOLF 127(50),提示对生活质量有中等影响。BAST-24评分:检测91%(22),识别52%(25),记忆35%(20)。QVOLF与svQOD-NS具有较强的相关性(ρ = 0.797; p)。结论:QVOLF和svQOD-NS问卷对嗅觉功能障碍的评价比SNOT-22更敏感。缺乏与心理物理测试的相关性突出了将两种方法结合起来进行全面评估的必要性。
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引用次数: 0
Cross-cultural adaptation and psychometric validation of the Spanish version of the Nasal Polyposis Quality of Life Questionnaire (NPQ). 西班牙版鼻息肉病生活质量问卷(NPQ)的跨文化适应和心理测量学验证。
Pub Date : 2025-12-05 DOI: 10.1016/j.otoeng.2025.512310
María Alharilla Montilla-Ibáñez, Javier Modesto García-Fernández, M S Sánchez-Torices, M P Gómez-Gallego, M A Feliz-Fernández, R Lomas-Vega

Introduction: To perform the cross-cultural adaptation into Spanish and the psychometric validation of the Nasal Polyposis Quality of Life Questionnaire (NPQ) for use in patients with chronic rhinosinusitis with nasal polyps (CRSwNP).

Methods: A total of 140 adult patients diagnosed with CRSwNP were included. The original NPQ was adapted from Italian into Spanish following established international guidelines. Construct validity was assessed through exploratory factor analysis (EFA) with principal components. Internal consistency was analyzed using Cronbach's alpha coefficient. Test-retest reliability was determined by the intraclass correlation coefficient (ICC). Concurrent validity was examined using Pearson correlations with the SNOT-22 and NOSE-E questionnaires. Discriminant validity was analyzed using ROC curves.

Results: EFA revealed a five-factor structure explaining 67% of the total variance. The Spanish NPQ showed excellent internal consistency (Cronbach's α = 0.917) and high test-retest reliability (ICC = 0.991; 95% CI: 0.983-0.996). The standard error of measurement (SEM) was 2 points, and the minimal detectable change (MDC95) was 5 points. Strong correlations were observed with the NOSE-E (r = 0.802) and SNOT-22 (r = 0.870). The NPQ total score demonstrated high discriminative ability for severe symptoms (AUC = 0.947), with a cutoff point >41 providing 88.9% sensitivity and 93.3% specificity.

Conclusions: The Spanish version of the NPQ is a valid, reliable, and clinically useful instrument for assessing symptom burden in patients with CRSwNP. Its multidimensional structure allows capturing the specific impact of this phenotype and supports its use in both clinical practice and research.

前言:对慢性鼻窦炎合并鼻息肉(CRSwNP)患者的鼻息肉病生活质量问卷(NPQ)进行西班牙语的跨文化适应和心理计量学验证。方法:共纳入140例诊断为CRSwNP的成人患者。最初的NPQ是根据既定的国际准则从意大利语改编成西班牙语的。通过主成分探索性因子分析(EFA)评估结构效度。内部一致性采用Cronbach’s alpha系数进行分析。重测信度由类内相关系数(ICC)确定。同时效度采用与SNOT-22和NOSE-E问卷的Pearson相关性进行检验。采用ROC曲线分析判别效度。结果:EFA揭示了一个五因素结构,解释了总方差的67%。西班牙NPQ具有良好的内部一致性(Cronbach’s α = 0.917)和高的重测信度(ICC = 0.991; 95% CI: 0.983 ~ 0.996)。测量标准误差(SEM)为2分,最小可检测变化(MDC95)为5分。与NOSE-E (r = 0.802)和SNOT-22 (r = 0.870)有很强的相关性。NPQ总分对重症症状具有较高的鉴别能力(AUC = 0.947),截断点bbbb41的敏感性为88.9%,特异性为93.3%。结论:西班牙语版NPQ是评估CRSwNP患者症状负担的有效、可靠和临床有用的工具。它的多维结构允许捕获这种表型的具体影响,并支持其在临床实践和研究中的使用。
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引用次数: 0
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Acta otorrinolaringologica espanola
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