Acta otorrinolaringologica espanola最新文献

英文中文

Stratification of the severity of Chronic Obstructive Sialadenitis based on its impact on Quality of Life 基于对生活质量影响的慢性阻塞性涎腺炎严重程度分层。

Acta otorrinolaringologica espanola

Pub Date : 2025-07-01 DOI: 10.1016/j.otoeng.2025.512223

William Aragonés Sanzen-Baker , José Miguel Villacampa Aubá , Ignacio Alcalá Rueda , Jessica Mireya Santillán Coello , Gonzalo Díaz Tapia , Carlos Cenjor Español , Álvaro Sánchez Barrueco

Introduction

Chronic Obstructive Sialadenitis (COS) is a debilitating condition characterized by recurrent inflammation of the salivary glands due to excretory obstruction, significantly impacting patients’ quality of life (QoL). The COS Quality of Life Questionnaire (COSQ) has been validated to evaluate QoL in affected patients and to monitor changes post-treatment.

Materials and methods

This study included two patient groups with COS-affected glands. The first group of 342 patients completed the COSQ before minimally invasive surgery, while the second group of 215 patients completed both the COSQ and a Visual Analog Scale (VAS). Scores were analyzed and stratified into four severity categories: mild, moderate, severe, and very severe, based on COSQ outcomes.

Results

COSQ scores were distributed as follows: mild (12.87%), moderate (37.13%), severe (34.5%), and very severe (15.21%). A significant correlation was observed between COSQ and VAS scores, particularly in the moderate and severe categories. Stratification allowed for identification of patients with severe symptoms, aiding in tailored management.

Conclusion

The COSQ effectively assesses QoL in COS patients and aids in stratifying severity. This stratification can guide clinicians in developing personalized treatment strategies, monitoring disease progression, and evaluating treatment outcomes.

慢性阻塞性涎腺炎（Chronic Obstructive Sialadenitis， COS）是一种以唾液腺因排泄梗阻而复发性炎症为特征的衰弱性疾病，严重影响患者的生活质量。已验证COS生活质量问卷（COSQ）用于评估受影响患者的生活质量并监测治疗后的变化。材料和方法：本研究包括两组cos影响腺体的患者。第一组342例患者在微创术前完成COSQ，第二组215例患者同时完成COSQ和视觉模拟评分（VAS）。根据COSQ结果，对评分进行分析并将其分为轻度、中度、重度和极重度四个严重类别。结果：COSQ评分分布为：轻度（12.87%）、中度（37.13%）、重度（34.5%）、极重度（15.21%）。在COSQ和VAS评分之间观察到显著的相关性，特别是在中度和重度分类中。分层可以识别严重症状的患者，有助于量身定制的管理。结论：COSQ能有效评价COS患者的生活质量，有助于病情的分级。这种分层可以指导临床医生制定个性化的治疗策略，监测疾病进展，并评估治疗结果。

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引用次数: 0

Isolated frontal sinus angiofibroma with external forehead deformity: A case report 孤立性额窦血管纤维瘤合并额外畸形1例。

Acta otorrinolaringologica espanola

Pub Date : 2025-07-01 DOI: 10.1016/j.otoeng.2025.512227

Ali Tawfik, Ahmed Musaad Abd-Elfattah, Hisham Atef Ebada, Ahmad Muhammad Al-Arman, Donia Usama Hamza, Elsharawy Kamal

引用次数: 0

External ear affection in multiple myeloma 多发性骨髓瘤对外耳的影响。

Acta otorrinolaringologica espanola

Pub Date : 2025-07-01 DOI: 10.1016/j.otoeng.2025.512228

João Tavares Correia, Isabel Silva-Carvalho, Luís Meireles

引用次数: 0

Acoustic characteristics of the voice of children with cochlear implant 人工耳蜗儿童声音的声学特征。

Acta otorrinolaringologica espanola

Pub Date : 2025-07-01 DOI: 10.1016/j.otoeng.2025.512238

Faustino Núñez-Batalla , Ainoa Álvarez , Isabel Sandoval , Paula Sánchez , Estefanía Díaz-Fresno , Jorge Javier Ramírez , Maite Guntín , J. Gómez , Jose Luis Llorente , Verónica Suárez-Martínez

Introduction

Congenital profound bilateral hearing loss prevents the correct development of speech and voice. This study assesses certain acoustic parameters of the voice in order to determine their normality in the implanted population.

Method

Two population groups were studied. A control group consisting of 42 healthy pediatric patients, 22 boys and 20 girls, and a group of 22 pediatric patients, 11 boys and 11 girls with congenital profound hearing loss implanted bilaterally.

The variables median pitch, CPPS, jitter rap and shimmer apq5 were evaluated in an isolated phonation exercise and another in connected speech for the phoneme /a/ with the PRAAT program. Student's t-test and Wilcoxcon tests were applied.

Results

Significant intergroup differences were obtained for all variables in the vowel extracted from connected speech, but not in the sustained vowel. The hearing-impaired population showed some significant differences in the intra-group analysis. The experimental group showed better results in the vocal quality parameters, particularly jitter, shimmer and CPPS showed statistically significant differences.

Conclusion

Early bilateral implantation allows the cochlear implant user to approximate his acoustic values to normative values in terms of pitch, stability, quality and articulatory precision.

先天性双侧深度听力损失妨碍语言和声音的正确发展。本研究评估某些声学参数的声音，以确定他们的正常植入人群。方法：对两组人群进行研究。对照组42例，男22例，女20例；对照组22例，男11例，女11例，先天性深度听力损失患儿双侧植入术。使用PRAAT程序对音素/a/在孤立发声练习和连接语音中评估变量中位音、CPPS、抖动rap和闪烁apq5。采用学生t检验和Wilcoxcon检验。结果：从连接语音中提取的元音各变量组间差异显著，但持续元音组间差异不显著。听障人群在组内分析中有显著差异。实验组在音质参数上表现较好，尤其是抖动、闪音、CPPS差异有统计学意义。结论：早期双侧植入术可使人工耳蜗使用者在音高、稳定性、音质和发音精度等方面的声学值接近规范值。

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引用次数: 0

Comment on the article: Recurrent peritonsillar abscess in adults: Incidence and risk factors in a prospective longitudinal cohort 评论文章：成人复发性腹膜周围脓肿：前瞻性纵向队列的发病率和危险因素。

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512233

Francisco Javier García-Callejo, Miguel Juantegui Azpilicueta

引用次数: 0

Nebulized hyaluronic acid and xylitol based solution after turbinate radiofrequency ablation. A triple blind randomized multicentric clinical trial 鼻甲射频消融后雾化透明质酸和木糖醇溶液。一项三盲随机多中心临床试验。

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512218

Christian Calvo-Henríquez , Ainhoa García-Lliberos , Byron Maldonado-Alvarado , Miguel Rodriguez-Iglesias , David Lobo-Duro , Juan Maza-Solano , Serafín Sánchez-Gomez , Isam Alobid

Objective

This prospective, triple blind randomized clinical trial aims to specifically evaluate the effect of Aluneb® (hyaluronic acid plus xilitol) in the postoperative treatment of inferior turbinate radiofrequency in adults compared to nebulized isotonic saline.

Methods

Adults undergoing radiofrequency turbinate ablation were included. Treatment group received Aluneb® (hyaluronic acid plus xylitol) while the control group received nebulized isotonic saline for two months after treatment. Participants were studied the week before surgery (visit 0), and at 7, 15, 30 and 60 days after surgery. At all visits, participants underwent physical examination, rhinomanometry, SNOT-22, and visual analogue scale (VAS) of symptoms.

Results

34 participants were recruited. Crusts (endoscopy) were less in the Aluneb® hyaluronic acid plus xylitol group. Nasal crusting, epistaxis and nasal obstruction VAS were statistically significant lower. VAS for Rhinorrea, halitosis, cacosmia and pain and nasal resistance obtained lower self-reported values in the hyaluronic acid plus xilitol group, but these differences were not statistically significant.

Conclusions

Hyaluronic acid plus xilitol demonstrated promise in improving postoperative outcomes, future studies with larger sample sizes and different surgical techniques are encouraged.

目的：这项前瞻性、三盲随机临床试验旨在专门评估Aluneb®（透明质酸加西利醇）在成人下鼻甲术后射频治疗中的效果，并与雾化等渗盐水进行比较。方法：接受射频鼻甲消融的成人为研究对象。治疗组给予Aluneb®（透明质酸加木糖醇）治疗，对照组给予等渗生理盐水雾化治疗2个月。参与者在手术前一周（第0次访问）以及手术后7、15、30和60天进行研究。在所有访问中，参与者接受体格检查、鼻测压、SNOT-22和症状视觉模拟量表（VAS）。结果：招募了34名参与者。Aluneb®透明质酸加木糖醇组结痂（内窥镜检查）较少。鼻结皮、鼻出血、鼻塞VAS均有统计学意义。透明质酸加西利醇组鼻臭、口臭、鼻臭、疼痛和鼻阻力VAS自述值较低，但差异无统计学意义。结论：透明质酸加西利醇在改善术后预后方面表现出希望，鼓励未来更大样本量和不同手术技术的研究。

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引用次数: 0

Association of human papillomavirus (HPV) infection with the occurrence of second neoplasms and their prognostic impact in patients with oropharyngeal carcinoma 人乳头瘤病毒（HPV）感染与口咽癌患者第二肿瘤发生的关系及其对预后的影响

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512237

Julia Gayà , David Rubio , Cristina Valero , Cristina Vázquez-López , Anna Holgado , Miquel Quer , Xavier León

Introduction

This study analyses the incidence of second neoplasms in patients with oropharyngeal carcinoma according to human papillomavirus (HPV) status and its impact on survival.

Material and methods

A retrospective analysis of 583 patients with oropharyngeal cancer treated between 1991 and 2023 was performed. A total of 112 patients (19.2%) had HPV-positive tumours.

Results

During the follow-up, 181 patients (31.0%) had a second neoplasm. The 5-year and 10-year second neoplasm-free survival for HPV-negative patients were 60.5% and 37.5%, significantly lower than in HPV-positive patients, which were 88.2% and 70.8%, respectively (p = .0001). The 84.4% of second and subsequent neoplasms in HPV-negative patients occurred in locations associated with tobacco and alcohol use, compared to 65.5% in HPV-positive patients (p = .001). In comparison to HPV-positive patients with no history of toxics consumption, HPV-positive patients with severe toxics consumption had a significantly higher risk of second neoplasms in locations associated with tobacco and alcohol use (p = .003). The competitive mortality associated with the appearance of second and subsequent neoplasms was significantly higher for patients with HPV-negative tumours (p = .0001).

Conclusions

Patients with HPV-positive oropharyngeal carcinomas have a lower risk of second neoplasms and lower competitive mortality associated with the appearance of second neoplasms compared with HPV-negative patients.

前言：本研究根据人乳头瘤病毒（HPV）状态分析口咽癌患者第二肿瘤的发生率及其对生存的影响。材料和方法：回顾性分析1991年至2023年间583例口咽癌患者。112例（19.2%）患者有hpv阳性肿瘤。结果：随访期间，181例（31.0%）患者出现第二肿瘤。hpv阴性患者的5年和10年二次无瘤生存率分别为60.5%和37.5%，显著低于hpv阳性患者的88.2%和70.8% （P = 0.0001）。在hpv阴性患者中，84.4%的第二次及后续肿瘤发生在与烟草和酒精使用相关的部位，而hpv阳性患者中这一比例为65.5% （P = 0.001）。与没有毒物消费史的hpv阳性患者相比，严重毒物消费的hpv阳性患者在与烟草和酒精使用相关的部位发生第二肿瘤的风险明显更高（P = 0.003）。hpv阴性肿瘤患者与第二肿瘤及后续肿瘤出现相关的竞争性死亡率显著较高（P = 0.0001）。结论：与hpv阴性患者相比，hpv阳性口咽癌患者发生第二肿瘤的风险较低，与第二肿瘤出现相关的竞争性死亡率较低。

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引用次数: 0

Effect of bariatric surgery in the treatment of obstructive sleep apnea in obese patients 减肥手术治疗肥胖患者阻塞性睡眠呼吸暂停的效果。

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512221

Silvia Matarredona-Quiles , Marina Carrasco-Llatas , Paula Martínez-Ruíz de Apodaca , Jose Ángel Díez-Ares , Elena González-Turienzo , José Dalmau-Galofre

Purpose

To analyze the success rate of bariatric surgery in the treatment of obstructive sleep apnea (OSA) in obese patients and its related factors.

Methods

Longitudinal, prospective, single cohort study, with consecutive sampling including OSA patients aged 18–65 years intervened of bariatric surgery. An anamnesis regarding OSA, a complete upper airway (UA) exploration and a cardiorespiratory polygraphy (CRP) pre- and post-surgery were performed.

Results

Fifty-seven patients were included in this study. The overall surgical success and cure rates for bariatric surgery as a treatment for OSA were 61.4% and 52.6%, respectively. Factors predicting success were female sex (OR = 12.54; CI95% = 1.75–89.88, p = 0.012), age below 53 years old (OR = 7.24; CI95% = 1.48–35.51, p = 0.015) and pre-surgical weight below 105 kg (OR = 8.1; CI95% = 1.44–45.62, p = 0.018). Surgical success cases had lower weight and body mass index, greater weight loss, smaller postsurgical neck circumference and less palatal webbing, however these were not independent factors in the multivariate analysis.

Conclusions

Our results show that bariatric surgery is a feasible option for OSA treatment in obese patients, with a higher success rate in female, younger and thinner patients. Moreover, adipose tissue on the UA has been proven to decrease as a result of weight loss, although not correlated with surgery success in the treatment of OSA.

目的：分析减肥手术治疗肥胖患者阻塞性睡眠呼吸暂停（OSA）的成功率及其相关因素。方法：纵向、前瞻性、单队列研究，连续抽样18-65岁的OSA患者进行减肥手术干预。对OSA进行回顾性分析，术前和术后进行全上气道探查和心肺多导图（CRP）检查。结果：本研究纳入了57例患者。减肥手术治疗OSA的总体手术成功率和治愈率分别为61.4%和52.6%。预测成功的因素为女性(OR = 12.54；CI95% = 1.75 ~ 89.88, p = 0.012)，年龄小于53岁(OR = 7.24；CI95% = 1.48 ~ 35.51, p = 0.015)，术前体重小于105 kg (OR = 8.1；CI95% = 1.44-45.62, p = 0.018)。手术成功的患者体重和体质指数较低，体重减轻幅度较大，术后颈围较小，腭带较少，但这些不是多因素分析中的独立因素。结论：我们的研究结果表明，减肥手术是肥胖患者OSA治疗的一种可行的选择，女性、年轻、瘦弱患者的成功率更高。此外，UA上的脂肪组织已被证明由于体重减轻而减少，尽管与OSA治疗的手术成功无关。

{"title":"Effect of bariatric surgery in the treatment of obstructive sleep apnea in obese patients","authors":"Silvia Matarredona-Quiles , Marina Carrasco-Llatas , Paula Martínez-Ruíz de Apodaca , Jose Ángel Díez-Ares , Elena González-Turienzo , José Dalmau-Galofre","doi":"10.1016/j.otoeng.2025.512221","DOIUrl":"10.1016/j.otoeng.2025.512221","url":null,"abstract":"<div><h3>Purpose</h3><div>To analyze the success rate of bariatric surgery in the treatment of obstructive sleep apnea (OSA) in obese patients and its related factors.</div></div><div><h3>Methods</h3><div>Longitudinal, prospective, single cohort study, with consecutive sampling including OSA patients aged 18–65 years intervened of bariatric surgery. An anamnesis regarding OSA, a complete upper airway (UA) exploration and a cardiorespiratory polygraphy (CRP) pre- and post-surgery were performed.</div></div><div><h3>Results</h3><div>Fifty-seven patients were included in this study. The overall surgical success and cure rates for bariatric surgery as a treatment for OSA were 61.4% and 52.6%, respectively. Factors predicting success were female sex (OR = 12.54; CI95% = 1.75–89.88, p = 0.012), age below 53 years old (OR = 7.24; CI95% = 1.48–35.51, p = 0.015) and pre-surgical weight below 105 kg (OR = 8.1; CI95% = 1.44–45.62, p = 0.018). Surgical success cases had lower weight and body mass index, greater weight loss, smaller postsurgical neck circumference and less palatal webbing, however these were not independent factors in the multivariate analysis.</div></div><div><h3>Conclusions</h3><div>Our results show that bariatric surgery is a feasible option for OSA treatment in obese patients, with a higher success rate in female, younger and thinner patients. Moreover, adipose tissue on the UA has been proven to decrease as a result of weight loss, although not correlated with surgery success in the treatment of OSA.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512221"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cochleo-vestibular phenotype in patients with pathogenic variations in the ACTG1 gene ACTG1基因致病性变异患者的耳蜗-前庭表型

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512217

Rocío González-Aguado , Jaime Gallo-Terán , Eshter Onecha , Carmelo Morales-Angulo

Objective

This study aimed to investigate the prevalence of pathogenic, likely pathogenic, and variants of unknown significance in the ACTG1 gene among families with suspected bilateral sensorineural hearing loss of genetic origin. Additionally, the research aimed to elucidate the cochleovestibular phenotype of individuals carrying these variants.

Methods

A cohort of 365 unrelated families with sensorineural hearing loss participated in this study. Genetic analysis was conducted using Next-Generation Sequencing (NGS).

Results

The study identified c.94C>A and c.721G>A pathogenic variants in heterozygosity in the ACTG1 gene among three probands. Two of these cases exhibited an autosomal dominant inheritance pattern, while the third was a de novo variant. Additionally, three other family members underwent genetic and audiological evaluations. Onset of hearing loss typically occurred between the first and second decades of life, initially affecting high frequencies and gradually extending to all frequencies. Treatment with hearing aids yielded favourable outcomes in all cases.

Conclusions

Pathogenic variants in the ACTG1 gene were found to be rare in the studied population. Nonetheless, these variants should be considered in families presenting with postlingual bilateral sensorineural hearing loss, particularly when high-frequency hearing loss progressively worsens to profound levels.

目的：本研究旨在调查疑似双侧感音神经性听力损失的家庭中ACTG1基因致病性、可能致病性和未知意义变异的流行情况。此外，该研究旨在阐明携带这些变异的个体的耳蜗前庭表型。方法：对365个无亲缘关系的感音神经性听力损失家庭进行研究。采用新一代测序（NGS）进行遗传分析。结果：本研究在3个先证者中发现了ACTG1基因杂合性的c.94C>A和c.721G>A致病变异。其中两例表现为常染色体显性遗传模式，而第三例为新生变异。此外，另外三名家庭成员接受了遗传和听力学评估。听力损失通常发生在生命的第一个和第二个十年之间，最初影响高频，逐渐扩展到所有频率。在所有病例中，助听器治疗都取得了良好的结果。结论：ACTG1基因致病性变异在研究人群中罕见。尽管如此，在出现语后双侧感音神经性听力损失的家庭中，特别是当高频听力损失逐渐恶化到深度水平时，应该考虑这些变异。

{"title":"Cochleo-vestibular phenotype in patients with pathogenic variations in the ACTG1 gene","authors":"Rocío González-Aguado , Jaime Gallo-Terán , Eshter Onecha , Carmelo Morales-Angulo","doi":"10.1016/j.otoeng.2025.512217","DOIUrl":"10.1016/j.otoeng.2025.512217","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to investigate the prevalence of pathogenic, likely pathogenic, and variants of unknown significance in the <em>ACTG1</em> gene among families with suspected bilateral sensorineural hearing loss of genetic origin. Additionally, the research aimed to elucidate the cochleovestibular phenotype of individuals carrying these variants.</div></div><div><h3>Methods</h3><div>A cohort of 365 unrelated families with sensorineural hearing loss participated in this study. Genetic analysis was conducted using Next-Generation Sequencing (NGS).</div></div><div><h3>Results</h3><div>The study identified c.94C>A and c.721G>A pathogenic variants in heterozygosity in the <em>ACTG1</em> gene among three probands. Two of these cases exhibited an autosomal dominant inheritance pattern, while the third was a <em>de novo</em> variant. Additionally, three other family members underwent genetic and audiological evaluations. Onset of hearing loss typically occurred between the first and second decades of life, initially affecting high frequencies and gradually extending to all frequencies. Treatment with hearing aids yielded favourable outcomes in all cases.</div></div><div><h3>Conclusions</h3><div>Pathogenic variants in the <em>ACTG1</em> gene were found to be rare in the studied population. Nonetheless, these variants should be considered in families presenting with postlingual bilateral sensorineural hearing loss, particularly when high-frequency hearing loss progressively worsens to profound levels.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512217"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric maxillary expansion to treat nasal obstruction 小儿上颌扩张术治疗鼻塞。

Acta otorrinolaringologica espanola

Pub Date : 2025-05-01 DOI: 10.1016/j.otoeng.2025.512220

Christian Calvo-Henriquez , Pedro Martínez-Seijas , Antonino Maniaci , Juan Carlos Pérez-Varela , Sandra Kahn , Isam Alobid , Stanley Y. Liu

Objective

An often neglected cause of nasal obstruction is maxillary constriction. Maxillary expansion (ME) has been proven to decrease nasal resistance and increase nasal volume and airflow thus improving nasal obstruction symptoms both in adults and children. However, up to the present, studies have reported on patients with an orthodontic indication for ME, but not being treated for nasal obstruction. In this study we report a case series of pediatric patients who have been diagnosed with nasal obstruction attributed to maxillary constriction and who have been treated with ME.

Methods

Participants were consecutively selected. All children performed anterior active rhinomanometry and SN-5 questionnaire before and after ME. The longest follow-up visit to otolaryngology was recorded for this study. The inclusion criteria were children without adenoid or turbinate enlargement with persistent oral breathing and nasal obstruction confirmed through rhinomanometry. All included children were referred to their odontologist who performed ME only if it was safe for the patient.

Results

23 participants with a mean age of 10.1 (range 6.66–13.27) were included. 78.3% had been previously submitted to surgery to restore or improve nasal breathing. There was a mean decrease in nasal resistance of 0.13 Pa s/cm³, which is a reduction of 34.2% over the mean initial value (P < .001). There was a statistically significant correlation between the amount of expansion and the decrease in nasal resistance (Rho = 0.75; P < .001), and the increase in nasal airflow (rho = 0.71; P < .001). Participants demonstrated a statistically significant decrease in their nasal symptoms measured with the SN5 questionnaire (P = .033).

Conclusions

These are preliminary results that should be managed with caution. Considering previous reports which included ME performed for orthodontic reasons, and the case series herein presented, which includes ME performed for nasal breathing, it seems that ME could be used with this latter objective. Future controlled studies should corroborate these results before producing a general recommendation.

目的：上颌骨收缩是导致鼻阻塞的一个经常被忽视的原因。事实证明，上颌骨扩张术（ME）可以降低鼻阻力，增加鼻腔容积和气流，从而改善成人和儿童的鼻阻塞症状6。然而，到目前为止，研究报告都是针对有正畸适应症但未接受鼻阻塞治疗的患者。在本研究中，我们报告了一系列儿科患者的病例，这些患者被诊断出因上颌骨收缩导致鼻塞，并接受了ME治疗：方法：连续选择参与者。所有患儿在接受ME治疗前后均进行了前主动鼻测量和SN-5问卷调查。本研究记录了耳鼻喉科的最长随访时间。纳入标准是没有腺样体或鼻甲肥大、持续口呼吸和鼻阻塞的儿童，并通过鼻畸形测量得到确认。所有被纳入研究的儿童都被转诊至他们的口腔科医生，只有在对患者安全的情况下，医生才会为他们实施ME。78.3%的患者曾接受过恢复或改善鼻呼吸的手术。鼻阻力平均降低了 0.13 Pa s/cm3，比平均初始值降低了 34.2%（p 结论：这是初步结果，应加以控制：这些只是初步结果，应谨慎对待。考虑到之前的报告中包括因牙齿矫正而实施的 ME，以及本报告中包括因鼻呼吸而实施的 ME 的病例系列，ME 似乎可用于后一种目的。未来的对照研究应证实这些结果，然后再提出一般性建议。

{"title":"Pediatric maxillary expansion to treat nasal obstruction","authors":"Christian Calvo-Henriquez , Pedro Martínez-Seijas , Antonino Maniaci , Juan Carlos Pérez-Varela , Sandra Kahn , Isam Alobid , Stanley Y. Liu","doi":"10.1016/j.otoeng.2025.512220","DOIUrl":"10.1016/j.otoeng.2025.512220","url":null,"abstract":"<div><h3>Objective</h3><div>An often neglected cause of nasal obstruction is maxillary constriction. Maxillary expansion (ME) has been proven to decrease nasal resistance and increase nasal volume and airflow thus improving nasal obstruction symptoms both in adults and children. However, up to the present, studies have reported on patients with an orthodontic indication for ME, but not being treated for nasal obstruction. In this study we report a case series of pediatric patients who have been diagnosed with nasal obstruction attributed to maxillary constriction and who have been treated with ME.</div></div><div><h3>Methods</h3><div>Participants were consecutively selected. All children performed anterior active rhinomanometry and SN-5 questionnaire before and after ME. The longest follow-up visit to otolaryngology was recorded for this study. The inclusion criteria were children without adenoid or turbinate enlargement with persistent oral breathing and nasal obstruction confirmed through rhinomanometry. All included children were referred to their odontologist who performed ME only if it was safe for the patient.</div></div><div><h3>Results</h3><div>23 participants with a mean age of 10.1 (range 6.66–13.27) were included. 78.3% had been previously submitted to surgery to restore or improve nasal breathing. There was a mean decrease in nasal resistance of 0.13 Pa s/cm<sup>3</sup>, which is a reduction of 34.2% over the mean initial value (<em>P</em> < .001). There was a statistically significant correlation between the amount of expansion and the decrease in nasal resistance (Rho = 0.75; <em>P</em> < .001), and the increase in nasal airflow (rho = 0.71; <em>P</em> < .001). Participants demonstrated a statistically significant decrease in their nasal symptoms measured with the SN5 questionnaire (<em>P</em> = .033).</div></div><div><h3>Conclusions</h3><div>These are preliminary results that should be managed with caution. Considering previous reports which included ME performed for orthodontic reasons, and the case series herein presented, which includes ME performed for nasal breathing, it seems that ME could be used with this latter objective. Future controlled studies should corroborate these results before producing a general recommendation.</div></div>","PeriodicalId":93855,"journal":{"name":"Acta otorrinolaringologica espanola","volume":"76 3","pages":"Article 512220"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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