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PROFUGO study protocol: Predictive model for the early diagnosis of anastomotic leak after esophagectomy and gastrectomy. PROFUGO 研究方案:食管切除术和胃切除术后吻合口漏早期诊断的预测模型。
Pub Date : 2024-09-02 DOI: 10.1016/j.cireng.2024.06.012
Rocío Pérez Quintero, Marcos Bruna Esteban, Antonio José Serrano López

In esophagogastric surgery, the appearance of an anastomotic leak is the most feared complication. Early diagnosis is important for optimal management and successful resolution. For this reason, different studies have investigated the value of the use of markers to predict possible postoperative complications. Because of this, research and the creation of predictive models that identify patients at high risk of developing complications are mandatory in order to obtain an early diagnosis. The PROFUGO study (PRedictivO Model for Early Diagnosis of anastomotic LEAK after esophagectomy and gastrectomy) is proposed as a prospective and multicenter national study that aims to develop, with the help of artificial intelligence methods, a predictive model that allows for the identification of high-risk cases. of anastomotic leakage and/or major complications by analyzing different clinical and analytical variables collected during the postoperative period of patients undergoing esophagectomy or gastrectomy.

在食管胃手术中,出现吻合口漏是最可怕的并发症。早期诊断对于优化治疗和成功解决问题非常重要。因此,不同的研究都对使用标记物预测术后可能出现的并发症的价值进行了调查。因此,为了获得早期诊断,必须进行研究并建立预测模型,以确定哪些患者有发生并发症的高风险。PROFUGO 研究(食管切除术和胃切除术后吻合口漏早期诊断的 PRedictivO 模型)是一项前瞻性多中心全国性研究,旨在借助人工智能方法开发一种预测模型,通过分析食管切除术或胃切除术患者术后期间收集的不同临床和分析变量,识别吻合口漏和/或主要并发症的高风险病例。
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引用次数: 0
Non-inferiority clinical trial. Features and practical considerations. 非劣效性临床试验。特点和实际考虑因素。
Pub Date : 2024-09-02 DOI: 10.1016/j.cireng.2024.07.008
Xavier Serra-Aracil, Marc Fradera
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引用次数: 0
Clinical trial on nurse training through virtual reality simulation of an operating room: assessing satisfaction and outcomes 通过虚拟现实模拟手术室进行护士培训的临床试验:评估满意度和成果
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.04.012

Introduction

Virtual reality (VR) provides a firsthand active learning experience through varying degrees of immersion. The aim of this study is to evaluate the use of VR as a potential tool for training operating room nurses to perform thoracic surgery procedures.

Methods

This is an open parallel-group randomized clinical trial. One group received basic formation followed by an assessment module. The experimental group received the same basic formation, followed by thoracic surgery training and an assessment module.

Results

Fifty-six nurses participated in the study (51 females), with a mean age of 41.6 years. Participants achieved a median evaluation mode score of 480 points (IQR = 32 points). The experimental group (520 points) achieved an overall higher score than the control group (440 points; P = .04). Regarding age, women in the second quartile of age among the participants (35–41 years) achieved significantly better results than the rest (P = .04). When we evaluated the results based on the moment of practice, exercises performed in the last 10 min obtained better results than those performed in the first 10 min (1064 points versus 554 points; P < .001). Regarding adverse effects blurred vision was the most frequent. The overall satisfaction rating with the experience was 8.5 out of 10.

Conclusion

Virtual reality is a useful tool for training operating room nurses. Clinical trial with ISRCTN16864726 registered number.

引言 虚拟现实(VR)通过不同程度的沉浸感提供了第一手的主动学习体验。本研究旨在评估将 VR 用作培训手术室护士执行胸外科手术的潜在工具。一组接受基础培训,然后是评估模块。结果56名护士(51名女性)参加了研究,平均年龄41.6岁。参与者的评估模式得分中位数为 480 分(IQR = 32 分)。实验组(520 分)的总分高于对照组(440 分;P = .04)。在年龄方面,参与者中年龄处于第二四分位数(35-41 岁)的女性取得的成绩明显优于其他女性(P = .04)。当我们根据练习的时间来评估结果时,最后 10 分钟进行的练习比前 10 分钟进行的练习效果更好(1064 分对 554 分;P <.001)。关于不良反应,最常见的是视力模糊。结论虚拟现实技术是培训手术室护士的有用工具。注册号为 ISRCTN16864726 的临床试验。
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引用次数: 0
Prospective study about the security and efficacy of treatment without antibiotic therapy of patients diagnosed with acute uncomplicated diverticulitis after launching a protocol at a tertiary hospital 一项前瞻性研究,探讨在一家三级医院启动一项方案后,对确诊为急性无并发症憩室炎的患者进行无抗生素治疗的安全性和有效性。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.04.019

Introduction

The main objective of our study is to analyze the results in our hospital after launching a treatment protocol without antibiotic therapy for patients diagnosed with acute uncomplicated diverticulitis.

Methods

Our observational, prospective, single-center study was developed after launching a treatment protocol without antibiotic therapy for patients diagnosed with acute uncomplicated diverticulitis (AUD) in January 2021. The follow-up period was from January 1, 2021 to September 30, 2023. Variables evaluated by the study have included demographic and analytical variables, as well as those related to diagnosis and whether the patients needed to start antibiotic treatment, inpatient treatment, or surgical procedures.

Results

In total, 199 patients were diagnosed with AUD, 75 of whom were treated without antibiotic therapy as outpatients. Seven of these patients needed to start antibiotic treatment because of adverse evolution; none of these patients required surgical procedures. The need for inpatient treatment, urgent care, or surgical procedures is similar to the group of patients treated with antibiotics.

The main risk factor of failure of outpatient treatment without antibiotic therapy identified by the study was the presence of bacteriuria at diagnosis.

Conclusions

Our results confirm previous reports, observing that treatment without antibiotic therapy in selected patients with AUD is safe.

导言本研究的主要目的是分析我院对急性无并发症憩室炎患者实施无抗生素治疗方案后的效果:我们的观察性、前瞻性、单中心研究是在 2021 年 1 月对诊断为急性无并发症憩室炎 (AUD) 的患者启动无抗生素治疗方案后开展的。随访期为 2021 年 1 月 1 日至 2023 年 9 月 30 日。研究评估的变量包括人口统计学变量和分析变量,以及与诊断和患者是否需要开始抗生素治疗、住院治疗或外科手术有关的变量:共有 199 名患者被诊断为 AUD,其中 75 名患者在门诊接受了无抗生素治疗。其中 7 名患者因不良反应而需要开始抗生素治疗;这些患者中没有人需要接受手术治疗。需要住院治疗、紧急护理或手术治疗的患者与接受抗生素治疗的患者相似。研究发现,不使用抗生素治疗的门诊治疗失败的主要风险因素是诊断时存在菌尿:我们的研究结果证实了之前的报道,即对选定的 AUD 患者不使用抗生素治疗是安全的。
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引用次数: 0
Standardization of the definition of the types of oncological colectomy. Delphi method for consensus of experts of the Spanish Association of Surgeons 肿瘤结肠切除术类型定义的标准化。西班牙外科医生协会专家通过德尔菲法达成共识。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.05.012

There is no international consensus on the definition of the type of oncological resection that corresponds to each of the colectomies existing in the current literature.

The objective is to define for each colectomy described in the literature: embryological dissection plane, vascular pedicles in which to perform central ligation, the extent of the colectomy, and the need for resection of the greater momentum.

A consensus of experts is carried out through the Delphi methodology through two rounds from the Coloproctology Section of the Spanish Association of Surgeons. Study period: November 2021-January 2023. 120 experts were surveyed.

Degrees of consensus: Very strong: >90%, Strong: 80%–90%, Moderate: 50%–80%, No consensus: <50%.

The definition for each oncological colectomy was established by very strong, and strong recommendations.

Each oncological colectomy was established as Right hemicolectomy (RHC), RHC with D3 lymphadenectomy, Extended-RHC, transverse colon segmental colectomy, splenic flexure segmental colectomy, subtotal colectomy, total colectomy, left hemicolectomy (LHC), extended-LHC, sigmoidectomy.

对于目前文献中每种结肠切除术所对应的肿瘤切除类型的定义,国际上尚未达成共识。我们的目标是为文献中描述的每种结肠切除术定义:胚胎学解剖平面、进行中央结扎的血管蒂、结肠切除术的范围以及是否需要切除大动量。西班牙外科医生协会结肠直肠分会的专家们通过德尔菲法进行了两轮讨论,达成了共识。研究期限:2021 年 11 月至 2023 年 1 月。120 名专家接受了调查。共识程度:非常一致:>90%,较强:80-90%,中等:50-80%,无共识:50-80%:50-80%,无共识:
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引用次数: 0
Surgical management of recurrent intraparietal hernia following disruption of the semilunar line by pararectus incision 副肛门切开术破坏半月线后复发性顶叶内疝的手术治疗。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.05.017
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引用次数: 0
Interpretation and critical appraisal of a systematic review and/or meta-analysis 解释和批判性阅读系统综述和/或荟萃分析。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.04.007
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引用次数: 0
Local Excision for organ preservation in early REctal cancer with No Adjuvant treatment (LORENA Trial): prospective observational study protocol 无辅助治疗的早期直肠癌保留器官局部切除术(LORENA 试验):前瞻性观察研究方案。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.04.013

Introduction

Local resection (LR) is an alternative to total mesorectal excision (TME) that avoids its associated morbidity to the detriment of oncological radicality in early stages of rectal cancer. There are several conditioning factors for the success of this strategy, such as poor prognosis histological factors (PPHF), involvement of resection margins, clinical under staging, or complications that may lead to the indication for radical surgery with TME.

Patients and method

An international multicenter prospective observational open-label study has been designed. Consecutive patients diagnosed with early rectal cancer (cT1N0 on MRI +/− endorectal ultrasound) whose lower limit is a maximum of 2 cm proximal to the ano-rectal junction will be included. The primary objective of the study is to determine the overall prevalence of PPHF after LR and requiring TME or postoperative radio-chemotherapy.

Discussion

The prevalence of PPHF conditioning the success of LR in early distal rectal cancer has been scarcely studied in the literature, and there are very few prospective data. Considering the increasing interest in the watch and wait strategy in rectal cancer and its possible application in early-stage tumors, it seems necessary to know this information.

The results of this study will help guide clinical practice in patients with early distal rectal cancer. It will also provide quality information for the design of future comparative studies to improve organ preservation success in these patients.

Trial registration number: NCT05927584.

导言:局部切除术(LR)是全直肠系膜切除术(TME)的一种替代方案,在直肠癌的早期阶段,它可以避免与之相关的发病率,但不利于肿瘤根治。这一策略的成功有几个条件因素,如预后不良的组织学因素(PPHF)、切除边缘受累、临床分期不足或可能导致TME根治术指征的并发症:设计了一项国际多中心前瞻性开放标签观察研究。该研究将连续纳入被诊断为早期直肠癌(核磁共振成像+/-肛门直肠超声检查结果为cT1N0)且下限在肛门直肠交界处近端不超过2厘米的患者。研究的主要目的是确定 LR 后需要 TME 或术后放射化疗的 PPHF 的总体发病率:讨论:文献中几乎没有研究早期远端直肠癌 LR 成功与否的 PPHF 发生率,前瞻性数据也非常少。考虑到人们对直肠癌观察和等待策略的兴趣与日俱增,以及该策略在早期肿瘤中的可能应用,了解这些信息似乎很有必要。这项研究的结果将有助于指导早期远端直肠癌患者的临床实践。它还将为设计未来的比较研究提供高质量的信息,以提高这些患者的器官保留成功率:NCT05927584.
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引用次数: 0
Neurofibroma of the vagus nerve as an incidental finding during left modified radical neck dissection for papillary thyroid cancer 甲状腺乳头状癌左侧改良根治性颈部切除术中偶然发现的迷走神经神经纤维瘤。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2023.12.004
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引用次数: 0
Use of systematic review and meta-analysis in surgery: Quality assessment, identification of deficient areas, and points for improvement 在外科手术中使用系统综述和荟萃分析:质量评估、确定不足之处和改进要点。
Pub Date : 2024-09-01 DOI: 10.1016/j.cireng.2024.04.005
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引用次数: 0
期刊
Cirugia espanola
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