首页 > 最新文献

Gait & posture最新文献

英文 中文
Alteration of gait characteristics in patients with adult spinal deformity 成人脊柱畸形患者步态特征的改变
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.107
Stephanie Huysmans, Rachel Senden, Eva Jacobs, Paul Willems, Rik Marcellis, Mark van den Boogaart, Kenneth Meijer, Paul Willems
Patients with Adult Spinal Deformity(ASD) have distorted spinal alignment altering their gait pattern [1–3]. However, the deformity may differ between patients previously known with adolescent idiopathic scoliosis(AIS) and ‘de novo’ or degenerative lumbar scoliosis. AIS patients often have normal sagittal alignment on static radiographs, but display postural malalignment in frontal plane [4], while DSc patients experience sagittal malalignment [2,3,5]. The purpose of this project is to compare spatiotemporal parameters(SPT) and 3D trunk kinematic waveforms of both adult patients with symptomatic idiopathic scoliosis(ISc) and adult ‘de novo’ scoliosis(DSc) patients with controls during walking. Are SPT and 3D trunk kinematic waveforms of ISc and DSc patients different from matched controls during walking? ASD patients(n=50) scheduled for long-segment spinal fusion surgery were included and divided into an ISc(n=24, median(Q1-Q3) age 20(19-27) years, leg length 0.9(0.85-0.93) m, BMI 23.1(20.7-26.7) kg/m2), and a DSc(n=26, median(Q1-Q3) age 60.5(55-66) years, leg length 0.89(0.83-0.93) m, BMI 28.1(25.1-30.1) kg/m2) group. Each patient was matched to an age-, gender-, weight- and height asymptomatic healthy control. Gait was measured while walking at comfortable speed on an instrumented treadmill with 3D motion capture system surrounded by a 180° projection screen displaying a virtual environment. The human body lower limb model with trunk markers was used[6]. 250 steps were recorded and averages over all measured steps per individual were used for analyses. SPT were presented as median(interquartile range). Independent t-test or Mann-Whitney U test was used to compare the patients with their control group. Statistical Parametric Mapping(independent t-test) was used to compare 3D trunk kinematics between the groups. Patients with ISc walked with comparable SPT to controls, whereas patients with DSc walked significantly slower(0.99(0.73-1.14) vs 1.30(1.13-1.39) m/s) with lower cadence (108.4(101.8-113.3) vs 118.3 (111.3-122.8) steps/min), smaller (1.08(0.84-1.28) vs 1.29(1.21-1.37) m) but wider steps (20(18-24) vs 16(14-20) cm), and increased stride- (1.11(1.07-1.18) vs 1.02(0.98-1.08) s), stance- (0.70(0.66-0.76) vs 0.61(0.58-0.66) s), and double support time (0.14(0.12-0.17) vs 0.11(0.09-0.13) s). Compared to their matched controls, DSc patients showed significantly increased anterior trunk tilt during the whole gait cycle, while ISc patients walked with significantly increased trunk lateroflexion during stance(0-52% gait cycle; Fig. 1). Both DSc and ISc patients had comparable trunk rotation compared to controls(Fig. 1). Fig. 1. 3D Trunk kinematic waveforms. Patients in green andcontrols in grey. Statistical Parametric Mapping statistics are presented.Download : Download high-res image (137KB)Download : Download full-size image ISc and DSc patients show different gait alterations compared to controls. ISc patients show decreased trunk lateroflexion
成人脊柱畸形(Adult Spinal deformation, ASD)患者脊柱排列扭曲,从而改变其步态模式[1-3]。然而,以前已知的青少年特发性脊柱侧凸(AIS)和“新生”或退行性腰椎侧凸患者的畸形可能不同。AIS患者在静态x线片上矢状面排列正常,但在额位面显示体位失调[4],而DSc患者则出现矢状面排列失调[2,3,5]。本项目的目的是比较成年症状性特发性脊柱侧凸(ISc)患者和成年“新生”脊柱侧凸(DSc)患者行走时的时空参数(SPT)和三维躯干运动学波形。ISc和DSc患者行走时的SPT和3D躯干运动波形与对照组不同吗?纳入拟行长节段脊柱融合手术的ASD患者(n=50),分为ISc组(n=24,中位年龄(Q1-Q3) 20(19-27)岁,腿长0.9(0.85-0.93)m, BMI 23.1(20.7-26.7) kg/m2)和DSc组(n=26,中位年龄(Q1-Q3) 60.5(55-66)岁,腿长0.89(0.83-0.93)m, BMI 28.1(25.1-30.1) kg/m2)。每位患者与年龄、性别、体重和身高无症状的健康对照者相匹配。步态测量是在一个仪器跑步机上以舒适的速度行走,该跑步机上有3D运动捕捉系统,周围有一个180°的投影屏幕显示虚拟环境。采用带躯干标记的人体下肢模型[6]。记录了250步,并使用每个人所有测量步数的平均值进行分析。SPT以中位数(四分位数范围)表示。采用独立t检验或Mann-Whitney U检验将患者与对照组进行比较。采用统计参数映射(独立t检验)比较各组之间的三维躯干运动学。患者与可比SPT ISc走控制,而患者DSc走明显慢(0.99(0.73 - -1.14)和1.30 (1.13 - -1.39)m / s)节奏较低(108.4(101.8 - -113.3)和118.3(111.3 - -122.8)步骤/分钟)、小(1.08(0.84 - -1.28)和1.29(1.21 - -1.37)米)但更广泛的措施(20(18 - 24)和16个14到20厘米),并增加步幅-(1.11(1.07 - -1.18)和1.02 (0.98 - -1.08)s),立场——(0.70(0.66 - -0.76)和0.61 (0.58 - -0.66)),和双支撑时间(0.14(0.12-0.17)vs 0.11(0.09-0.13) s)。与对照组相比,DSc患者在整个步态周期中躯干前倾明显增加,而ISc患者在站立时躯干侧屈明显增加(0-52%步态周期;图1)。与对照组相比,DSc和ISc患者的躯干旋转相似(图1)。1).图1。三维主干运动波形。绿色的是病人,灰色的是对照组。给出了统计参数映射统计。下载:下载高分辨率图像(137KB)下载:下载全尺寸图像与对照组相比,ISc和DSc患者表现出不同的步态改变。ISc患者表现为躯干侧屈减少,提示行走时额平面体位失调,而DSc患者表现为躯干前倾增加。此外,DSc患者的行走速度随着站立时间的增加而减慢,步幅更小、更宽,这可能与稳定性有关[7,8]。需要进一步研究动态脊柱对齐参数来阐明ASD对三维运动波形的影响。
{"title":"Alteration of gait characteristics in patients with adult spinal deformity","authors":"Stephanie Huysmans, Rachel Senden, Eva Jacobs, Paul Willems, Rik Marcellis, Mark van den Boogaart, Kenneth Meijer, Paul Willems","doi":"10.1016/j.gaitpost.2023.07.107","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.107","url":null,"abstract":"Patients with Adult Spinal Deformity(ASD) have distorted spinal alignment altering their gait pattern [1–3]. However, the deformity may differ between patients previously known with adolescent idiopathic scoliosis(AIS) and ‘de novo’ or degenerative lumbar scoliosis. AIS patients often have normal sagittal alignment on static radiographs, but display postural malalignment in frontal plane [4], while DSc patients experience sagittal malalignment [2,3,5]. The purpose of this project is to compare spatiotemporal parameters(SPT) and 3D trunk kinematic waveforms of both adult patients with symptomatic idiopathic scoliosis(ISc) and adult ‘de novo’ scoliosis(DSc) patients with controls during walking. Are SPT and 3D trunk kinematic waveforms of ISc and DSc patients different from matched controls during walking? ASD patients(n=50) scheduled for long-segment spinal fusion surgery were included and divided into an ISc(n=24, median(Q1-Q3) age 20(19-27) years, leg length 0.9(0.85-0.93) m, BMI 23.1(20.7-26.7) kg/m2), and a DSc(n=26, median(Q1-Q3) age 60.5(55-66) years, leg length 0.89(0.83-0.93) m, BMI 28.1(25.1-30.1) kg/m2) group. Each patient was matched to an age-, gender-, weight- and height asymptomatic healthy control. Gait was measured while walking at comfortable speed on an instrumented treadmill with 3D motion capture system surrounded by a 180° projection screen displaying a virtual environment. The human body lower limb model with trunk markers was used[6]. 250 steps were recorded and averages over all measured steps per individual were used for analyses. SPT were presented as median(interquartile range). Independent t-test or Mann-Whitney U test was used to compare the patients with their control group. Statistical Parametric Mapping(independent t-test) was used to compare 3D trunk kinematics between the groups. Patients with ISc walked with comparable SPT to controls, whereas patients with DSc walked significantly slower(0.99(0.73-1.14) vs 1.30(1.13-1.39) m/s) with lower cadence (108.4(101.8-113.3) vs 118.3 (111.3-122.8) steps/min), smaller (1.08(0.84-1.28) vs 1.29(1.21-1.37) m) but wider steps (20(18-24) vs 16(14-20) cm), and increased stride- (1.11(1.07-1.18) vs 1.02(0.98-1.08) s), stance- (0.70(0.66-0.76) vs 0.61(0.58-0.66) s), and double support time (0.14(0.12-0.17) vs 0.11(0.09-0.13) s). Compared to their matched controls, DSc patients showed significantly increased anterior trunk tilt during the whole gait cycle, while ISc patients walked with significantly increased trunk lateroflexion during stance(0-52% gait cycle; Fig. 1). Both DSc and ISc patients had comparable trunk rotation compared to controls(Fig. 1). Fig. 1. 3D Trunk kinematic waveforms. Patients in green andcontrols in grey. Statistical Parametric Mapping statistics are presented.Download : Download high-res image (137KB)Download : Download full-size image ISc and DSc patients show different gait alterations compared to controls. ISc patients show decreased trunk lateroflexion","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical evaluation of sitting postural control in infants: A systematic review 婴儿坐姿控制的生物力学评价:系统综述
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.08.022
Maria Gkaraveli, Theofani Bania, Pavlos Morfis, Eirini Grammatopoulou, Vasiliki Sakellari
{"title":"Biomechanical evaluation of sitting postural control in infants: A systematic review","authors":"Maria Gkaraveli, Theofani Bania, Pavlos Morfis, Eirini Grammatopoulou, Vasiliki Sakellari","doi":"10.1016/j.gaitpost.2023.08.022","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.08.022","url":null,"abstract":"","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Muscle quality: Intramuscular fat, collagen fibres, and mechanical properties in the triceps surae 肌肉质量:肌内脂肪、胶原纤维和三头肌表面的机械特性
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.264
Zhongzheng Wang, Francesco Cenni, Iida Laatikainen-Raussi, Taija Finni, Ruoli Wang
Skeletal muscle architecture provides valuable insights for individuals with neuromuscular diseases, such as cerebral palsy (CP) [1]. Yet, to have a comprehensive view of muscle remodelling and better-informed clinical treatments, muscle quality (i.e. intramuscular fat, collagen fibres, and mechanical properties) should also be explored [2]. This comprehensive view can be achieved in a non-invasive image-based manner by combing magnetic resonance imaging (MRI) and shear wave elastography (SWE). What is the relationship between intramuscular fat fraction or T2 relaxation time and muscle mechanical properties? One individual with CP (13 years, male, GMFCS I) and four typically developing (TD, 17.3±7.9 years, 4 females) peers were enrolled in the study. Medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SOL) were assessed in neutral position (middle position between maximal dorsiflexed and plantarflexed position; CP -15.0°, TD -16.3±6.3°), while participants were laying prone with knee extended. SWE (Aixplorer, Supersonic Imagine) was recorded for MG and LG at mid-muscle belly, for SOL distally below the LG muscle-tendon junction. Shear modulus was estimated by means of an open-source software (ELASTOGUI, University of Nantes). Fat fraction and T2 relaxation times were estimated from modified Dixon and T2 mapping sequence using a 3.0-Tesla MR scanner (Ingenia CX, Philips Healthcare) at the same ankle position as SWE measurements. The intramuscular fat fraction was calculated based on 2-point fat-water separation [3]. T2 relaxation time is a quantitative parameter indicating collagen fibres content [4]. The correlation between shear modulus and fat fraction / T2 relaxation time was evaluated using linear correlation coefficient. Overall, the individual with CP showed higher muscle shear moduli than TD peers (Figure A) in all three muscles. The individual with CP had a similar fat content in MG and LG but higher fat content in SOL than TD peers (Figure B&F). Regarding the collagen fibres, the average T2 relaxation time for all three muscles were similar in both groups (Figure C). Overall, the correlation between muscle shear modulus and fat fraction / T2 relaxation time was weak (R=0.24 for fat fraction, R=-0.10 for T2 relaxation time, Figure D&E). Figure. (A-C) Average shear modulus, fat fraction, and T2 relaxation time. (D-E) Correlation between shear modulus and fat fraction / T2 relaxation time. The scatter points mean the imaging parameter and related shear modulus for all subjects. (F-G) Sample fat fraction and T2 maps. Download : Download high-res image (178KB)Download : Download full-size image This study is a first attempt to comprehensively analyze muscle quality in CP by combining MRI and SWE. It confirms the increased muscle fat fraction in CP [5], whilst no difference for T2 relaxation time was observed. The correlation results suggested higher passive muscle stiffness with higher fat content. These preliminary results nee
骨骼肌结构为脑瘫(CP)等神经肌肉疾病患者提供了宝贵的见解[1]。然而,为了全面了解肌肉重塑和更好的临床治疗,还应该探索肌肉质量(即肌内脂肪、胶原纤维和力学性能)[2]。通过结合磁共振成像(MRI)和横波弹性成像(SWE),可以以一种无创的基于图像的方式获得这种全面的视图。肌内脂肪含量或T2松弛时间与肌肉力学性能有何关系?1例CP患者(13岁,男性,GMFCS I)和4例发育典型的TD患者(17.3±7.9岁,4例女性)被纳入研究。腓肠肌内侧(MG)、腓肠肌外侧(LG)和比目鱼肌(SOL)在中立位(最大背屈位和跖屈位之间的中间位置;CP -15.0°,TD -16.3±6.3°),受试者俯卧,膝关节伸直。在中肌腹部的MG和LG, LG肌-肌腱连接处远端以下的SOL记录了SWE (aiexplorer, Supersonic Imagine)。剪切模量通过开源软件(ELASTOGUI, University of Nantes)估算。使用3.0-Tesla MR扫描仪(Ingenia CX, Philips Healthcare)在与SWE测量相同的脚踝位置,根据改进的Dixon和T2制图序列估计脂肪分数和T2松弛时间。肌内脂肪分数采用2点脂水分离法计算[3]。T2松弛时间是反映胶原纤维含量的定量参数[4]。用线性相关系数评价剪切模量与脂肪分数/ T2松弛时间的相关性。总体而言,CP患者的三块肌肉剪切模量均高于TD患者(图A)。CP患者的MG和LG脂肪含量相似,但SOL脂肪含量高于TD患者(图B&F)。在胶原纤维方面,两组三种肌肉的平均T2松弛时间相似(图C)。总体而言,肌肉剪切模量与脂肪分数/ T2松弛时间之间的相关性较弱(脂肪分数R=0.24, T2松弛时间R=-0.10,图D&E)。数字(A-C)平均剪切模量、脂肪分数和T2松弛时间。(D-E)剪切模量与脂肪分数/ T2松弛时间的相关性。散点表示所有受试者的成像参数和相关剪切模量。(F-G)样品脂肪分数和T2图。下载:下载高分辨率图像(178KB)下载:下载全尺寸图像本研究首次尝试结合MRI和SWE对CP的肌肉质量进行综合分析。它证实了CP中肌肉脂肪含量的增加[5],而T2松弛时间没有观察到差异。相关结果表明,脂肪含量越高,被动肌肉僵硬度越高。一旦收集到更大的样本,这些初步结果需要得到证实。
{"title":"Muscle quality: Intramuscular fat, collagen fibres, and mechanical properties in the triceps surae","authors":"Zhongzheng Wang, Francesco Cenni, Iida Laatikainen-Raussi, Taija Finni, Ruoli Wang","doi":"10.1016/j.gaitpost.2023.07.264","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.264","url":null,"abstract":"Skeletal muscle architecture provides valuable insights for individuals with neuromuscular diseases, such as cerebral palsy (CP) [1]. Yet, to have a comprehensive view of muscle remodelling and better-informed clinical treatments, muscle quality (i.e. intramuscular fat, collagen fibres, and mechanical properties) should also be explored [2]. This comprehensive view can be achieved in a non-invasive image-based manner by combing magnetic resonance imaging (MRI) and shear wave elastography (SWE). What is the relationship between intramuscular fat fraction or T2 relaxation time and muscle mechanical properties? One individual with CP (13 years, male, GMFCS I) and four typically developing (TD, 17.3±7.9 years, 4 females) peers were enrolled in the study. Medial gastrocnemius (MG), lateral gastrocnemius (LG), and soleus (SOL) were assessed in neutral position (middle position between maximal dorsiflexed and plantarflexed position; CP -15.0°, TD -16.3±6.3°), while participants were laying prone with knee extended. SWE (Aixplorer, Supersonic Imagine) was recorded for MG and LG at mid-muscle belly, for SOL distally below the LG muscle-tendon junction. Shear modulus was estimated by means of an open-source software (ELASTOGUI, University of Nantes). Fat fraction and T2 relaxation times were estimated from modified Dixon and T2 mapping sequence using a 3.0-Tesla MR scanner (Ingenia CX, Philips Healthcare) at the same ankle position as SWE measurements. The intramuscular fat fraction was calculated based on 2-point fat-water separation [3]. T2 relaxation time is a quantitative parameter indicating collagen fibres content [4]. The correlation between shear modulus and fat fraction / T2 relaxation time was evaluated using linear correlation coefficient. Overall, the individual with CP showed higher muscle shear moduli than TD peers (Figure A) in all three muscles. The individual with CP had a similar fat content in MG and LG but higher fat content in SOL than TD peers (Figure B&F). Regarding the collagen fibres, the average T2 relaxation time for all three muscles were similar in both groups (Figure C). Overall, the correlation between muscle shear modulus and fat fraction / T2 relaxation time was weak (R=0.24 for fat fraction, R=-0.10 for T2 relaxation time, Figure D&E). Figure. (A-C) Average shear modulus, fat fraction, and T2 relaxation time. (D-E) Correlation between shear modulus and fat fraction / T2 relaxation time. The scatter points mean the imaging parameter and related shear modulus for all subjects. (F-G) Sample fat fraction and T2 maps. Download : Download high-res image (178KB)Download : Download full-size image This study is a first attempt to comprehensively analyze muscle quality in CP by combining MRI and SWE. It confirms the increased muscle fat fraction in CP [5], whilst no difference for T2 relaxation time was observed. The correlation results suggested higher passive muscle stiffness with higher fat content. These preliminary results nee","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Selective motor control may be associated with the single support time of gait and single limb standing time in cerebral palsy 选择性运动控制可能与脑瘫患者单步支撑时间和单肢站立时间有关
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.188
Yunus Ozdemir, Nazif Ekin Akalan, Yener Temelli
The Selective Motor Control Assessment of the Lower Extremity (SCALE) is a tool used to assess the quality of motor control of the lower extremity in cerebral palsy (CP). Selective motor control (SMC) is known to be associated with balance and some walking alterations, as well as a significant sign for gross motor function (1-3). It is well known that the single limb stance has a strong relationship with the stability in stance which is the main aim of physiotherapy for improving the quality of walking for CP (4). Therefore the aim of this study is to determine the relationship between SMC, single-limb standing (SLS) time and single support time (SST) of gait in CP. Is there any relationship between SMC with SLS time and SST of gait in individuals with CP? In this study, 10 individuals with spastic type diplegics CP (mean age: 12,7±5,86) were included and bilateral limbs (n:20) were evaluated. Inclusion criteria were GMFCS level I or II, walk 10 meters without assistive device. Patients who had undergone surgery or had botulinum toxin injections in the last 6 months were excluded. The Selective Control Assessment of the Lower Extremity (SCALE) was performed on the hip (S1), knee (S2), subtalar (S3), ankle (S4) and toes (S5) joint for SMC. In addition, the total foot score (TFS) was calculated by summing the subtalar, ankle and toe joint scores; and the total score (TS) is calculated by summing all joints. Independent SLS score of the Gross Motor Function Measure was applied (three point scale). The interested gait parameters of each individual were analyzed with a pedobarography (Win-track, Balma, France). The SST was normalized by dividing stance time. For each parameter, 3 averaged trials were included. Pearson and Spearman’s correlation with Cohen's classification were used for statistical analysis (5). S3, TFS and TS had a strongly positive correlation with SLS score. There was a moderate positive correlation between S5 and SST (Table 1). Download : Download high-res image (207KB)Download : Download full-size image Strong positive correlation of total foot and total scores on SCALE test with single limb stance may show that improving total SMC, especially on subtalar joints, may increase the time of independent standing on one leg. Although only SMC at toes has the moderate level correlation with SST which is also the parameter related with stability in stance phase (4). Therefore improving motor control on toe flex-extension may have a great potential on increasing stance phase stability for CP. It is worthwhile to design randomized control studies with a large number of participants to analyze the relationship of improving SMC and stability in the stance phase by 3D gait analysis in the future.
选择性下肢运动控制评估(Selective Motor Control Assessment of The Lower Extremity, SCALE)是一种用于评估脑瘫患者下肢运动控制质量的工具。选择性运动控制(SMC)已知与平衡和一些行走改变有关,也是大运动功能的重要标志(1-3)。众所周知,单肢站立与站立稳定性有很强的关系,而站立稳定性是CP物理治疗提高行走质量的主要目的(4)。因此,本研究的目的是确定SMC与CP中单肢站立(SLS)时间和步态单支撑时间(SST)之间的关系。在CP个体中,SMC与SLS时间和步态SST之间是否存在关系?本研究纳入10例痉挛性双瘫CP患者(平均年龄:12、7±5、86),对20例双侧肢体进行评估。纳入标准为GMFCS I级或II级,无辅助器具行走10米。排除在过去6个月内接受过手术或注射过肉毒杆菌毒素的患者。对髋关节(S1)、膝关节(S2)、距下关节(S3)、踝关节(S4)和脚趾关节(S5)进行下肢选择性控制评估(SCALE)。此外,将距下、踝关节和脚趾关节评分相加计算足部总评分(TFS);总得分(TS)由所有关节之和计算。采用大肌肉运动功能量表独立SLS评分(三分制)。对每个个体感兴趣的步态参数进行足部摄影分析(Win-track, Balma, France)。通过除以姿态时间对海表温度进行归一化。对于每个参数,包括3次平均试验。采用Pearson和Spearman与Cohen分类的相关性进行统计分析(5)。S3、TFS、TS与SLS评分呈强正相关。S5与SST之间存在中等正相关(表1)。下载:下载高分辨率图像(207KB)下载:下载全尺寸图像单肢站立时,全足与SCALE测试总分呈强正相关,可能表明改善全足SMC,特别是距下关节,可以增加单腿独立站立的时间。虽然只有趾部SMC与SST有中等程度的相关性,而SST也是与站立阶段稳定性相关的参数(4)。因此,改善趾部屈伸运动控制可能对提高CP的站立阶段稳定性有很大的潜力。未来值得设计大量参与者的随机对照研究,通过三维步态分析来分析改善SMC与站立阶段稳定性的关系。
{"title":"Selective motor control may be associated with the single support time of gait and single limb standing time in cerebral palsy","authors":"Yunus Ozdemir, Nazif Ekin Akalan, Yener Temelli","doi":"10.1016/j.gaitpost.2023.07.188","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.188","url":null,"abstract":"The Selective Motor Control Assessment of the Lower Extremity (SCALE) is a tool used to assess the quality of motor control of the lower extremity in cerebral palsy (CP). Selective motor control (SMC) is known to be associated with balance and some walking alterations, as well as a significant sign for gross motor function (1-3). It is well known that the single limb stance has a strong relationship with the stability in stance which is the main aim of physiotherapy for improving the quality of walking for CP (4). Therefore the aim of this study is to determine the relationship between SMC, single-limb standing (SLS) time and single support time (SST) of gait in CP. Is there any relationship between SMC with SLS time and SST of gait in individuals with CP? In this study, 10 individuals with spastic type diplegics CP (mean age: 12,7±5,86) were included and bilateral limbs (n:20) were evaluated. Inclusion criteria were GMFCS level I or II, walk 10 meters without assistive device. Patients who had undergone surgery or had botulinum toxin injections in the last 6 months were excluded. The Selective Control Assessment of the Lower Extremity (SCALE) was performed on the hip (S1), knee (S2), subtalar (S3), ankle (S4) and toes (S5) joint for SMC. In addition, the total foot score (TFS) was calculated by summing the subtalar, ankle and toe joint scores; and the total score (TS) is calculated by summing all joints. Independent SLS score of the Gross Motor Function Measure was applied (three point scale). The interested gait parameters of each individual were analyzed with a pedobarography (Win-track, Balma, France). The SST was normalized by dividing stance time. For each parameter, 3 averaged trials were included. Pearson and Spearman’s correlation with Cohen's classification were used for statistical analysis (5). S3, TFS and TS had a strongly positive correlation with SLS score. There was a moderate positive correlation between S5 and SST (Table 1). Download : Download high-res image (207KB)Download : Download full-size image Strong positive correlation of total foot and total scores on SCALE test with single limb stance may show that improving total SMC, especially on subtalar joints, may increase the time of independent standing on one leg. Although only SMC at toes has the moderate level correlation with SST which is also the parameter related with stability in stance phase (4). Therefore improving motor control on toe flex-extension may have a great potential on increasing stance phase stability for CP. It is worthwhile to design randomized control studies with a large number of participants to analyze the relationship of improving SMC and stability in the stance phase by 3D gait analysis in the future.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135298851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Muscle activity of upper extremity during the is tennis forehand overhead smash: Experimental VS musculoskeletal modeling 网球正手顶扣球时上肢肌肉活动:实验VS肌肉骨骼模型
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.162
Sheida Shourabadi Takabi, Meroeh Mohammadi, Reza Najarpour
One of the main parts of body that play key role in tennis matches is shoulder complex [1,2]. There are many joints and muscles caused shoulder to be complex [2–5]. Evaluation of the muscle activities is necessary to improve safety and performance [5]. The fundamental challenge for evaluation of muscle activity is measuring by EMG due to limitation of equipment, expensiveness, and inaccessibility to deep muscles [6–8]. Therefore, it is important to use musculoskeletal modeling to evaluate muscle activation [9–12]. On the other hand, there have been different musculoskeletal models with different joint definitions and the DOF [13,14]. Thus, the goal of this study was to validate the muscle activation output from different model by EMG data for the TFOS. How does muscle activity from experimental and modeling valuations change during the tennis forehand overhead smash (TFOS)? Twenty-five professional tennis athletes (Mass: 69.3±7.5 kg, Heights: 178±9.3 cm, Age: 29.5±7.5 years). The kinematics of markers were recorded by a 12 high-speed motion captures (Vicon, Oxford, UK, 100 Hz). The shoulder model of Holzbaur et al. [15–17] selected as base model and three version of models extracted based on the DOF: (5 DOF) a model with only three rotational DOF between humerus and trunk Glenohumeral joint, (11 DOF) a model with three rotational DOF for Scapulothoracic joint, Acromioclavicular joint, and Glenohumeral joint, (Stanford) a model with coupled motions for scapula, clavicle, and humerus. All models include two DOF for radio-ulna and elbow joints. After scaling the models, the inverse kinematics, inverse dynamics, and static optimization tools were applied to compute kinematics, kinetics, and muscle activity variables. The EMG activity in selective muscles was measured by the Myon wireless EMG system with a sampling frequency of 1000 Hz [18]. The average RMS of differences between each model and EMG (RMSE) over the muscles were 0.27±0.10, 0.29±0.12, and 0.22±0.10 for 5DOF, Stanford, and 11DOF models, respectively. Furthermore, the average Pearson's correlation coefficient over the muscles were 0.89±0.08, 0.88±0.09, and 0.93±0.60 for 5DOF, Stanford, and 11DOF models, respectively. The minimum RMS error (0.22±0.10) and maximum Pearson's correlation coefficient (0.93±0.60) were observed for 11 DOF model. Table 1: Muscle activity comparison between musculoskeletal simulation outputs (from three different models) and experimental data (EMG) including the RMSE, and Pearson's correlation coefficient for the TFOS movement.Download : Download high-res image (181KB)Download : Download full-size image According to the results, the 11 DOF model are more similar to the experimental (EMG) based on both RMSE and Pearson's correlation coefficient. Although the simulation results of some muscles were significantly different from the experimental results. Therefore, the alternative method to quantify muscle activation is musculoskeletal modeling. Moreover, the best mode
在网球比赛中发挥关键作用的主要身体部位之一是肩部复合体[1,2]。肩关节和肌肉众多,导致肩关节复杂[2-5]。对肌肉活动进行评估是提高安全性和运动表现的必要条件[5]。由于设备的限制、价格昂贵以及深层肌肉难以接近,肌电图测量是评估肌肉活动的基本挑战[6-8]。因此,使用肌肉骨骼模型来评估肌肉激活是很重要的[9-12]。另一方面,已有不同的肌肉骨骼模型,具有不同的关节定义和自由度[13,14]。因此,本研究的目的是通过肌电数据验证不同模型对TFOS的肌肉激活输出。在网球正手头顶扣杀(TFOS)中,肌肉活动如何从实验和模型评估中改变?职业网球运动员25名(体重:69.3±7.5公斤,身高:178±9.3厘米,年龄:29.5±7.5岁)。通过12台高速运动捕捉(Vicon, Oxford, UK, 100 Hz)记录标记物的运动学。选取Holzbaur等[15-17]的肩部模型作为基础模型,并根据自由度提取了三个版本的模型:(5 DOF)肱骨与躯干肩关节之间只有三个旋转自由度的模型,(11 DOF)肩胸关节、肩锁关节和肩关节三个旋转自由度的模型,(Stanford)肩胛骨、锁骨和肱骨耦合运动的模型。所有型号都包括桡尺骨和肘关节的两个自由度。在缩放模型后,应用逆运动学、逆动力学和静态优化工具来计算运动学、动力学和肌肉活动变量。使用Myon无线肌电系统测量选择性肌肉的肌电活动,采样频率为1000 Hz[18]。5DOF模型、Stanford模型和11DOF模型的肌电图(RMSE)与各模型差异的平均RMS分别为0.27±0.10、0.29±0.12和0.22±0.10。5DOF、Stanford和11DOF模型的平均Pearson相关系数分别为0.89±0.08、0.88±0.09和0.93±0.60。11自由度模型的RMS误差最小(0.22±0.10),Pearson相关系数最大(0.93±0.60)。表1:肌肉骨骼模拟输出(来自三种不同模型)与实验数据(肌电图)之间的肌肉活动比较,包括RMSE和TFOS运动的Pearson相关系数。下载:下载高分辨率图片(181KB)下载:下载全尺寸图片结果显示,基于RMSE和Pearson相关系数,11 DOF模型与实验(肌电图)更接近。虽然部分肌肉的模拟结果与实验结果有明显差异。因此,量化肌肉激活的替代方法是肌肉骨骼建模。此外,重建肌肉激活的最佳模型是11DOF模型。
{"title":"Muscle activity of upper extremity during the is tennis forehand overhead smash: Experimental VS musculoskeletal modeling","authors":"Sheida Shourabadi Takabi, Meroeh Mohammadi, Reza Najarpour","doi":"10.1016/j.gaitpost.2023.07.162","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.162","url":null,"abstract":"One of the main parts of body that play key role in tennis matches is shoulder complex [1,2]. There are many joints and muscles caused shoulder to be complex [2–5]. Evaluation of the muscle activities is necessary to improve safety and performance [5]. The fundamental challenge for evaluation of muscle activity is measuring by EMG due to limitation of equipment, expensiveness, and inaccessibility to deep muscles [6–8]. Therefore, it is important to use musculoskeletal modeling to evaluate muscle activation [9–12]. On the other hand, there have been different musculoskeletal models with different joint definitions and the DOF [13,14]. Thus, the goal of this study was to validate the muscle activation output from different model by EMG data for the TFOS. How does muscle activity from experimental and modeling valuations change during the tennis forehand overhead smash (TFOS)? Twenty-five professional tennis athletes (Mass: 69.3±7.5 kg, Heights: 178±9.3 cm, Age: 29.5±7.5 years). The kinematics of markers were recorded by a 12 high-speed motion captures (Vicon, Oxford, UK, 100 Hz). The shoulder model of Holzbaur et al. [15–17] selected as base model and three version of models extracted based on the DOF: (5 DOF) a model with only three rotational DOF between humerus and trunk Glenohumeral joint, (11 DOF) a model with three rotational DOF for Scapulothoracic joint, Acromioclavicular joint, and Glenohumeral joint, (Stanford) a model with coupled motions for scapula, clavicle, and humerus. All models include two DOF for radio-ulna and elbow joints. After scaling the models, the inverse kinematics, inverse dynamics, and static optimization tools were applied to compute kinematics, kinetics, and muscle activity variables. The EMG activity in selective muscles was measured by the Myon wireless EMG system with a sampling frequency of 1000 Hz [18]. The average RMS of differences between each model and EMG (RMSE) over the muscles were 0.27±0.10, 0.29±0.12, and 0.22±0.10 for 5DOF, Stanford, and 11DOF models, respectively. Furthermore, the average Pearson's correlation coefficient over the muscles were 0.89±0.08, 0.88±0.09, and 0.93±0.60 for 5DOF, Stanford, and 11DOF models, respectively. The minimum RMS error (0.22±0.10) and maximum Pearson's correlation coefficient (0.93±0.60) were observed for 11 DOF model. Table 1: Muscle activity comparison between musculoskeletal simulation outputs (from three different models) and experimental data (EMG) including the RMSE, and Pearson's correlation coefficient for the TFOS movement.Download : Download high-res image (181KB)Download : Download full-size image According to the results, the 11 DOF model are more similar to the experimental (EMG) based on both RMSE and Pearson's correlation coefficient. Although the simulation results of some muscles were significantly different from the experimental results. Therefore, the alternative method to quantify muscle activation is musculoskeletal modeling. Moreover, the best mode","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does a single segment trunk model adequately reveal trunk movements for a simple reaching and grasping movement? 单节躯干模型是否充分揭示了简单的伸手和抓握动作的躯干运动?
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.216
Maria B. Sánchez, Andy Sanderson, Emma Hodson-Tole
The trunk represents almost 50% of the total mass of a person [1] and, because it comprises multiple segments, has a large range of motion [2]. Trunk posture and movement are important in the execution of activities of daily living (ADL), especially for those related with arm function [3]. However, in movement analysis, the trunk is usually defined as a single rigid, cylindrical segment between the shoulders and pelvis. This oversimplification ignores the large movement potential the trunk has [2], and therefore does not enable a complete evaluation of trunk movement. Does a single segment trunk model adequately reveal trunk movements for a simple reaching and grasping movement? The University Ethics Committee (ref:47565) approved the project. Eleven people (7 male; (mean ±SD) age: 27.82 ±3.18years, height: 1.74 ±0.11 m; weight: 75.0 ±12.7 kg) participated after signing the consent form. An upper-body marker-set was used: left/right acromion, iliac-crest, ASIS; manubrium, S1; five inverted “L” clusters of 3 markers: two 2.5 cm lateral of C7, T3, T7, T11 and L3, with the third marker on the long end of the “L” with the length adjusted based on the participant’ s size. These defined a single-segment-trunk (acromia to iliac-crests), and upper-, mid- and lower-thoracic, and upper- and lower-lumbar segments (multi-segment-trunk). Participants were asked to stand from a hight-adjustable bench, walk to a low table and lean to collect a mug before returning to the bench. Motion capture data were recorded (100 Hz), tracked, and processed. Segmental angles (in relation to the absolute coordinate system) were estimated for the “leaning to collect” section of each trial. The total displacement in each plane and a combined 3D movement (sum of the three planes) of the single-segment-trunk and of the multi-segment-trunk compared with a paired sample t-test. Table 1 shows the difference in the combined 3D movement for the single-segment-trunk when compared to the multi-segment-trunk (t = 27.95, p<.01) and for each of the planes of movement (t = 18.21, 11.19, 14.15, p<.01, for sagittal, frontal and horizontal). The standardised mean difference was considered very large (8.07 ±8.06).Download : Download high-res image (82KB)Download : Download full-size image This simplified approach identified the scale of additional information that could be gained from a multi-segment-trunk. Further exploration should focus on understanding if the amount of movement in a multi-segment-trunk vs single-segment-trunk is of a very different magnitude; it should also look specifically at where are the more important differences. Additional development might focus on understanding the best representation of the trunk movement when assessing ADL in clinical populations. I would say this phrasing is better, calling your approach very simple is an insult to your work, calling it simplified indicates that you’re just presenting in a simple way for them.
躯干几乎占人体总质量的50%,由于它由多个节段组成,因此活动范围很大。躯干姿势和运动在日常生活活动(ADL)的执行中很重要,特别是对于那些与手臂功能有关的人。然而,在运动分析中,躯干通常被定义为肩膀和骨盆之间的单一刚性圆柱形部分。这种过度简化忽略了躯干具有的巨大运动潜力,因此不能对躯干运动进行完整的评估。单节躯干模型是否充分揭示了简单的伸手和抓握动作的躯干运动?大学伦理委员会(ref:47565)批准了该项目。11人(男性7人;(mean±SD)年龄:27.82±3.18岁,身高:1.74±0.11 m;体重:75.0±12.7 kg)签署同意书后参加。采用上肢标记组:左/右肩峰、髂嵴、ASIS;柄,S1;5个倒立的“L”串,每串3个标记:C7、T3、T7、T11和L3的两个2.5 cm侧面,第三个标记位于“L”的长端,长度根据参与者的体型调整。这些定义了单节段躯干(肩峰至髂嵴),上、中、下胸椎节段以及上、下腰椎节段(多节段躯干)。参与者被要求站在一个高度可调节的长凳上,走到一张低矮的桌子前,弯腰去拿杯子,然后再回到长凳上。记录运动捕捉数据(100hz),跟踪和处理。对每次试验的“学习收集”部分的节段角度(相对于绝对坐标系)进行估计。与配对样本t检验相比,单节段主干和多节段主干在每个平面上的总位移和组合三维运动(三个平面的总和)。表1显示了单节段躯干与多节段躯干联合三维运动的差异(t = 27.95, p< 0.01)以及各运动平面的差异(t = 18.21, 11.19, 14.15, p< 0.01)。01,为矢状,额状和水平)。标准化平均差(8.07±8.06)认为非常大。下载:下载高分辨率图像(82KB)下载:下载全尺寸图像这种简化的方法确定了可以从多段中继中获得的额外信息的规模。进一步的探索应该集中在了解多段主干与单段主干的运动量是否具有非常不同的幅度;它还应该特别关注更重要的差异在哪里。在临床人群中评估ADL时,进一步的发展可能集中在了解躯干运动的最佳代表上。我想说这个措辞更好,说你的方法非常简单是对你工作的侮辱,说它简化表明你只是用一种简单的方式向他们展示。
{"title":"Does a single segment trunk model adequately reveal trunk movements for a simple reaching and grasping movement?","authors":"Maria B. Sánchez, Andy Sanderson, Emma Hodson-Tole","doi":"10.1016/j.gaitpost.2023.07.216","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.216","url":null,"abstract":"The trunk represents almost 50% of the total mass of a person [1] and, because it comprises multiple segments, has a large range of motion [2]. Trunk posture and movement are important in the execution of activities of daily living (ADL), especially for those related with arm function [3]. However, in movement analysis, the trunk is usually defined as a single rigid, cylindrical segment between the shoulders and pelvis. This oversimplification ignores the large movement potential the trunk has [2], and therefore does not enable a complete evaluation of trunk movement. Does a single segment trunk model adequately reveal trunk movements for a simple reaching and grasping movement? The University Ethics Committee (ref:47565) approved the project. Eleven people (7 male; (mean ±SD) age: 27.82 ±3.18years, height: 1.74 ±0.11 m; weight: 75.0 ±12.7 kg) participated after signing the consent form. An upper-body marker-set was used: left/right acromion, iliac-crest, ASIS; manubrium, S1; five inverted “L” clusters of 3 markers: two 2.5 cm lateral of C7, T3, T7, T11 and L3, with the third marker on the long end of the “L” with the length adjusted based on the participant’ s size. These defined a single-segment-trunk (acromia to iliac-crests), and upper-, mid- and lower-thoracic, and upper- and lower-lumbar segments (multi-segment-trunk). Participants were asked to stand from a hight-adjustable bench, walk to a low table and lean to collect a mug before returning to the bench. Motion capture data were recorded (100 Hz), tracked, and processed. Segmental angles (in relation to the absolute coordinate system) were estimated for the “leaning to collect” section of each trial. The total displacement in each plane and a combined 3D movement (sum of the three planes) of the single-segment-trunk and of the multi-segment-trunk compared with a paired sample t-test. Table 1 shows the difference in the combined 3D movement for the single-segment-trunk when compared to the multi-segment-trunk (t = 27.95, p<.01) and for each of the planes of movement (t = 18.21, 11.19, 14.15, p<.01, for sagittal, frontal and horizontal). The standardised mean difference was considered very large (8.07 ±8.06).Download : Download high-res image (82KB)Download : Download full-size image This simplified approach identified the scale of additional information that could be gained from a multi-segment-trunk. Further exploration should focus on understanding if the amount of movement in a multi-segment-trunk vs single-segment-trunk is of a very different magnitude; it should also look specifically at where are the more important differences. Additional development might focus on understanding the best representation of the trunk movement when assessing ADL in clinical populations. I would say this phrasing is better, calling your approach very simple is an insult to your work, calling it simplified indicates that you’re just presenting in a simple way for them.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Design of cushioned footwear for children with obesity based on gait dynamics and motion simulation 基于步态动力学和运动模拟的肥胖儿童减震鞋设计
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.276
Yihong Zhao, Shiyang Yan, Ruoyi Li, Luming Yang, Bi Shi
Obesity will cause changes in foot structure and plantar pressure distribution, increasing the risk of foot pain and injury [1]. Functional footwear (outsole) is an essential way to distribute the local plantar pressure for children with obesity. However, the traditional design and research of outsoles need to go through the whole process of design, molding, production, fitting experiments, and so on, which is a long time and high-cost consumption. How to obtain the optimal design scheme of cushioned footwear for children with obesity through finite element analysis? Based on the database of foot morphology of children with obesity, a 3D outsole model was established, and the arch height of the outsole was set as 30%, 60%, and 100% of the arch height of children with obesity. Based on the anthropometric data, biomechanical data, and CT imaging data of children with obesity, a biomechanical simulation model of the lower limb musculoskeletal system and a finite element model of the foot were established. To verify the validity of the finite element model, the simulation results of the maximum principal stress of children with obesity during walking were compared with the actual measured data.The structure of the outsole is preliminarily constructed in Solidworks. The arch height (30%, 60%, and 100%) of the outsole was set to simulate the support at the arch. The foot-outsole-ground structure was assembled, and the pressure on the foot-shoe interface was simulated in ANSYS Workbench, to explore the dispersion effect of different arch heights. After obtaining the best design scheme, the actual relief effect of the outsoles was tested through the try-on trials. The simulation results showed that the 60% arch height support could effectively achieve the dispersion of plantar pressure in the plantar toe area and heel area. The try-on results showed that, when wearing the cushioned footwear, the peak pressure in the central forefoot and heel were relieved by 36.8% and 43.8%, respectively, from176.5 kPa and 310.9 kPa to 111.6 kPa and 174.7 kPa. Fig. 1 (a) 3D model of coushioned outsole. (b) Finite element analysis and verfication results. (c) Construction and assembly of the outsole structure. (d) The finite element analysis results between foot and outsole with the 60% arch height. (e) The cushioned footwear. (f) The cushioned effects of the outsole in the try-on experiments.Download : Download high-res image (244KB)Download : Download full-size image Through finite element analysis and fitting verification test, we found that when the arch height of the outsole is 60% of the arch height of the children with obesity, the decompression function is the best, which can transfer the pressure of the front palm and heel to the arch and toe. Finite element analysis makes functional shoe development process more efficient.
肥胖会引起足部结构和足底压力分布的改变,增加足部疼痛和损伤的风险[1]。功能鞋(大底)是肥胖儿童分配足底局部压力的重要途径。但是,传统的外底设计研究需要经过设计、成型、生产、试穿实验等全过程,时间长、成本高。如何通过有限元分析得到肥胖儿童减震鞋的最佳设计方案?根据肥胖儿童足部形态数据库,建立3D大底模型,设置大底足弓高度分别为肥胖儿童足弓高度的30%、60%和100%。基于肥胖儿童的人体测量数据、生物力学数据和CT成像数据,建立了下肢肌肉骨骼系统的生物力学仿真模型和足部的有限元模型。为了验证有限元模型的有效性,将肥胖儿童行走过程中最大主应力的仿真结果与实测数据进行对比。在Solidworks中初步构建了大底的结构。设置外底的足弓高度(30%,60%和100%)来模拟足弓处的支撑。对脚-外底-地面结构进行拼装,在ANSYS Workbench中模拟脚-鞋界面上的压力,探讨不同拱高的分散效应。获得最佳设计方案后,通过试穿试验,检验了外底的实际救济效果。仿真结果表明,60%足弓高度支撑能有效实现足底压力在足趾区和足跟区分散。试穿结果表明,穿缓冲鞋后,前足中央和脚跟的峰值压力分别从176.5 kPa和310.9 kPa降低到111.6 kPa和174.7 kPa,分别减轻了36.8%和43.8%。图1 (a)衬垫外底三维模型。(b)有限元分析和验证结果。(c)外底结构的建造和装配。(d) 60%拱高时足部与大底之间的有限元分析结果。(e)有衬垫的鞋子。(f)试穿实验中大底的缓冲效果。通过有限元分析和拟合验证试验,我们发现,当大底足弓高度为肥胖儿童足弓高度的60%时,减压功能最好,可以将前掌和脚跟的压力传递到足弓和脚趾。有限元分析使功能性鞋的开发过程更加高效。
{"title":"Design of cushioned footwear for children with obesity based on gait dynamics and motion simulation","authors":"Yihong Zhao, Shiyang Yan, Ruoyi Li, Luming Yang, Bi Shi","doi":"10.1016/j.gaitpost.2023.07.276","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.276","url":null,"abstract":"Obesity will cause changes in foot structure and plantar pressure distribution, increasing the risk of foot pain and injury [1]. Functional footwear (outsole) is an essential way to distribute the local plantar pressure for children with obesity. However, the traditional design and research of outsoles need to go through the whole process of design, molding, production, fitting experiments, and so on, which is a long time and high-cost consumption. How to obtain the optimal design scheme of cushioned footwear for children with obesity through finite element analysis? Based on the database of foot morphology of children with obesity, a 3D outsole model was established, and the arch height of the outsole was set as 30%, 60%, and 100% of the arch height of children with obesity. Based on the anthropometric data, biomechanical data, and CT imaging data of children with obesity, a biomechanical simulation model of the lower limb musculoskeletal system and a finite element model of the foot were established. To verify the validity of the finite element model, the simulation results of the maximum principal stress of children with obesity during walking were compared with the actual measured data.The structure of the outsole is preliminarily constructed in Solidworks. The arch height (30%, 60%, and 100%) of the outsole was set to simulate the support at the arch. The foot-outsole-ground structure was assembled, and the pressure on the foot-shoe interface was simulated in ANSYS Workbench, to explore the dispersion effect of different arch heights. After obtaining the best design scheme, the actual relief effect of the outsoles was tested through the try-on trials. The simulation results showed that the 60% arch height support could effectively achieve the dispersion of plantar pressure in the plantar toe area and heel area. The try-on results showed that, when wearing the cushioned footwear, the peak pressure in the central forefoot and heel were relieved by 36.8% and 43.8%, respectively, from176.5 kPa and 310.9 kPa to 111.6 kPa and 174.7 kPa. Fig. 1 (a) 3D model of coushioned outsole. (b) Finite element analysis and verfication results. (c) Construction and assembly of the outsole structure. (d) The finite element analysis results between foot and outsole with the 60% arch height. (e) The cushioned footwear. (f) The cushioned effects of the outsole in the try-on experiments.Download : Download high-res image (244KB)Download : Download full-size image Through finite element analysis and fitting verification test, we found that when the arch height of the outsole is 60% of the arch height of the children with obesity, the decompression function is the best, which can transfer the pressure of the front palm and heel to the arch and toe. Finite element analysis makes functional shoe development process more efficient.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
There is life outside the gait lab: Effectiveness of a self-organising neural map for recognising 24/7 activities of daily living 步态实验室之外还有生活:一种自组织神经地图的有效性,用于识别日常生活中的24/7活动
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.08.018
Gabor Barton, Jacob Beesley, Jasmine Milnes, Gabriela Czanner, Lynne Boddy
{"title":"There is life outside the gait lab: Effectiveness of a self-organising neural map for recognising 24/7 activities of daily living","authors":"Gabor Barton, Jacob Beesley, Jasmine Milnes, Gabriela Czanner, Lynne Boddy","doi":"10.1016/j.gaitpost.2023.08.018","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.08.018","url":null,"abstract":"","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reliability of 3D kinematic recording of jaw and head movements 下颌和头部运动的三维运动学记录的可靠性
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.171
Evelina Nilsson, Helena Grip, Catharina Österlund
The jaw and neck sensorimotor systems are functionally integrated during jaw functions1,2. The jaw border movements include maximum opening, laterotrusion to left and right, protrusion and retrusion3. Three-dimensional (3D) kinematic movement analysis provide data to distinguish natural movement patterns from those adapted to pain and dysfunction. Therefore, the reliability of kinematics is crucial to assess movement variability of integrated jaw-neck motor capacity. Can we ensure a high accuracy of the novel method intended to use for estimation of maximum jaw movements and geometric characterization (area and volume)? Is there a high test-retest reliability and intraindividual consistency for a group of healthy participants performing maximum jaw movements? 3D kinematic analysis was used for movement recognition. The first part included three glass beakers of different sizes, with known volumes and the cross-sectional area was estimated with a geometrical algorithm. The percentage deviation between target values and estimated values was calculated and to test the agreement a linear regression was made. The second part included 17 healthy participants (25.37 years ± 2.36). Maximum jaw movements were performed in a pre-determined movement pattern to track reflective marker positions of jaw and head segments. Movement amplitudes, magnitudes, areas, and volumes were analyzed. Intraclass correlation coefficient (ICC)4 estimates and Bland-Altman plots5 were used to assess test – retest reliability. Coefficient of variation (CV)6 tested the within session reliability. Preliminary results for the beakers showed a total percentage deviation from the target area and volume of 0.03 (SD 0.59) and 0.72 (SD 0.81), respectively. The linear regression showed a linear agreement between estimated and target value with R2=0.99. Preliminary results of test – retest reliability per movement outcome variable showed moderate to excellent reliability according to ICC-classification4. The limits of agreement between test and retest session presented with Bland-Altman plots showed good agreement between first and second measurement. The intra individual movement variability expressed as CV showed good repeatability. Jaw movements including the horizontal directions displayed widest ICC 95% confidence interval and highest CV values. (Fig. 1. Coefficient of variation - box plots).Download : Download high-res image (67KB)Download : Download full-size image This study addressed reliability of kinematic parameters of maximum jaw movements and its geometrics. The preliminary main findings indicate high accuracy of the novel method for estimations of volume and area. The agreement between sessions was considered good as well as consistency in repeated movements. Moreover, the more complex movement, the lower reliability and higher variability was seen. In future research of jaw-neck motor function the presented method is suggested to enables valid analysis of jaw movement perf
颌骨和颈部感觉运动系统在颌骨功能中是功能整合的1,2。下颌边界运动包括最大开口、向左右侧挤、前突和后缩3。三维(3D)运动学运动分析提供了区分自然运动模式和适应疼痛和功能障碍的运动模式的数据。因此,运动学的可靠性对于评估综合颌颈运动能力的运动变异性至关重要。我们能否确保用于估计最大下颌运动和几何特征(面积和体积)的新方法的高精度?对于一组健康的参与者进行最大的下颌运动,是否存在高的重测信度和个体内一致性?采用三维运动学分析进行运动识别。第一部分包括三个不同大小的玻璃烧杯,体积已知,横截面积用几何算法估计。计算了目标值与估计值之间的百分比偏差,并进行了线性回归检验。第二部分纳入17名健康受试者(25.37岁±2.36岁)。在预先确定的运动模式下进行最大下颌运动,以跟踪下颌和头部部分的反射标记位置。分析运动幅度、幅度、面积和体积。用类内相关系数(ICC)4估计和Bland-Altman图5评估检验-重测信度。变异系数(CV)6检验了会话内信度。初步结果表明,烧杯与目标面积和体积的总偏差百分比分别为0.03 (SD 0.59)和0.72 (SD 0.81)。线性回归表明估计值与目标值线性一致,R2=0.99。根据icc分类,每个运动结果变量的测试-重测信度的初步结果显示中等至优异的信度。用Bland-Altman图表示的测试和复测之间的一致性界限表明第一次和第二次测量之间的一致性很好。以CV表示的个体内运动变异性具有良好的重复性。包括水平方向在内的下颌运动显示出最宽的ICC 95%置信区间和最高的CV值。(图1所示。变异系数(箱形图)。下载:下载高分辨率图像(67KB)下载:下载全尺寸图像本研究解决了最大下颌运动及其几何参数的可靠性问题。初步结果表明,该方法具有较高的体积和面积估算精度。两次训练之间的一致性和重复动作的一致性被认为是好的。运动越复杂,可靠性越低,变异率越高。在今后对颌颈运动功能的研究中,提出了一种有效分析下颌运动性能的方法。
{"title":"Reliability of 3D kinematic recording of jaw and head movements","authors":"Evelina Nilsson, Helena Grip, Catharina Österlund","doi":"10.1016/j.gaitpost.2023.07.171","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.171","url":null,"abstract":"The jaw and neck sensorimotor systems are functionally integrated during jaw functions1,2. The jaw border movements include maximum opening, laterotrusion to left and right, protrusion and retrusion3. Three-dimensional (3D) kinematic movement analysis provide data to distinguish natural movement patterns from those adapted to pain and dysfunction. Therefore, the reliability of kinematics is crucial to assess movement variability of integrated jaw-neck motor capacity. Can we ensure a high accuracy of the novel method intended to use for estimation of maximum jaw movements and geometric characterization (area and volume)? Is there a high test-retest reliability and intraindividual consistency for a group of healthy participants performing maximum jaw movements? 3D kinematic analysis was used for movement recognition. The first part included three glass beakers of different sizes, with known volumes and the cross-sectional area was estimated with a geometrical algorithm. The percentage deviation between target values and estimated values was calculated and to test the agreement a linear regression was made. The second part included 17 healthy participants (25.37 years ± 2.36). Maximum jaw movements were performed in a pre-determined movement pattern to track reflective marker positions of jaw and head segments. Movement amplitudes, magnitudes, areas, and volumes were analyzed. Intraclass correlation coefficient (ICC)4 estimates and Bland-Altman plots5 were used to assess test – retest reliability. Coefficient of variation (CV)6 tested the within session reliability. Preliminary results for the beakers showed a total percentage deviation from the target area and volume of 0.03 (SD 0.59) and 0.72 (SD 0.81), respectively. The linear regression showed a linear agreement between estimated and target value with R2=0.99. Preliminary results of test – retest reliability per movement outcome variable showed moderate to excellent reliability according to ICC-classification4. The limits of agreement between test and retest session presented with Bland-Altman plots showed good agreement between first and second measurement. The intra individual movement variability expressed as CV showed good repeatability. Jaw movements including the horizontal directions displayed widest ICC 95% confidence interval and highest CV values. (Fig. 1. Coefficient of variation - box plots).Download : Download high-res image (67KB)Download : Download full-size image This study addressed reliability of kinematic parameters of maximum jaw movements and its geometrics. The preliminary main findings indicate high accuracy of the novel method for estimations of volume and area. The agreement between sessions was considered good as well as consistency in repeated movements. Moreover, the more complex movement, the lower reliability and higher variability was seen. In future research of jaw-neck motor function the presented method is suggested to enables valid analysis of jaw movement perf","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135299063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of perturbation on hip kinematics of transtibial amputees 摄动对经胫截肢者髋关节运动学的影响
Pub Date : 2023-09-01 DOI: 10.1016/j.gaitpost.2023.07.229
Nimet Sermenli Aydın, İlke Kurt, Halit Selçuk, Sinem Salar, Sezer Ulukaya, Hilal Keklicek
Gait adaptation to perturbations is essential for safe interaction with the physical environment and therefore it is important to understand how people with lower-limb amputation adapt their gait to changing conditions (1). Previous studies tried to find some deviation patterns and understand the kinematic strategies of amputee's gait (2). However, there is limited information available on the hip kinematics of amputees during gait and there is no study has yet investigated the effect of the perturbation on the hip kinematics of amputees. How does unpredictable continuous perturbation during gait affect the hip kinematics of unilateral transtibial amputees? Individuals with unilateral trans-tibial amputations and using prostheses with an active vacuum plus carbon foot combination were included in to study. Kinematic data of the hip were collected from 11 amputees and 10 healthy controls during walking on two different ground conditions. Participants walked at least 512 steps at their preferred speed on a motorized treadmill’s (ReaxRun Pro) flat ground condition and then the gait analysis was repeated on a perturbed (5% unpredictable perturbation) ground condition. RehaGait- Pro system was used for evaluation of the kinematics of the hip(min-max hip angles and variability of the hip min-max angles) during gait. Negative values indicated hip hyperextension, positive values indicated hip flexion. The statistical analysis was performed by pairing the residual limbs of amputees with the non-dominant side of the healthy group (RL side), and the sound limbs with the dominant side of the healthy group (HL side). It was observed that the hip hyperextension angle on the sound limb side was bigger in the amputees than in the control group on flat (d=0.462; p=0.034) and perturbated ground (d=0.584; p=0.007). The effect size was larger on the perturbed ground. There was no difference in the maximum hip angles and variability of max-min hip angles between the groups in both ground conditions (p>0.05). The results showed in Table.Download : Download high-res image (142KB)Download : Download full-size image Amputation-related changes were observed in hip kinematics during walking under both ground conditions. However, this change was more prominent on the perturbated ground. The reason for the higher hip hyperextension values in amputees is thought to be due to their efforts to compensate for the ankle (exp. strong plantar flexion) movements. On the unpredictable perturbation ground, the limitation of ankle movements, which is one of the first adaptive mechanisms in adaptation to the ground (exp. subtalar rotations plus plantarflexion), may have made the situation more evident. Future studies may focus on the effect of gait training on perturbed surfaces on gait kinematics, which is an indicator of adaptation to variable conditions.
对扰动的步态适应对于与物理环境的安全交互至关重要,因此了解下肢截肢者如何适应变化的条件非常重要(1)。先前的研究试图找到一些偏差模式并了解截肢者的步态运动学策略(2)。关于截肢者步态时髋关节运动学的信息有限,目前还没有研究调查摄动对截肢者髋关节运动学的影响。步态中不可预测的连续扰动如何影响单侧经胫截肢者的髋关节运动学?单侧经胫骨截肢和使用主动真空加碳足组合假体的个体被纳入研究。收集了11名截肢者和10名健康对照者在两种不同地面条件下行走时的髋关节运动学数据。参与者在电动跑步机(ReaxRun Pro)的平坦地面条件下以他们喜欢的速度行走至少512步,然后在扰动(5%不可预测的扰动)的地面条件下重复步态分析。使用RehaGait- Pro系统评估步态过程中髋关节的运动学(髋最小最大角度和髋最小最大角度的可变性)。阴性值表示髋关节过伸,阳性值表示髋关节屈曲。将截肢者残肢与健康组非优势侧配对(RL侧),健全肢与健康组优势侧配对(HL侧)进行统计分析。结果显示,截肢者的健全肢侧髋关节过伸角在平面上大于对照组(d=0.462;P =0.034)和扰动地面(d=0.584;p = 0.007)。扰动地面的效应值更大。两种地面条件下各组最大臀角和最大-最小臀角变异性均无显著差异(p>0.05)。结果见表。下载:下载高分辨率图像(142KB)下载:下载全尺寸图像在两种地面条件下行走时,观察到与截肢相关的髋关节运动学变化。然而,这种变化在受扰动的地面上更为明显。截肢者髋关节超伸值较高的原因被认为是由于他们努力补偿踝关节(例如强烈的足底屈曲)运动。在不可预测的扰动地面上,脚踝运动的限制,这是适应地面的第一个适应机制之一(例如,距下旋转和跖屈),可能使情况更加明显。未来的研究可能会集中在摄动表面上的步态训练对步态运动学的影响,这是适应可变条件的指标。
{"title":"The effect of perturbation on hip kinematics of transtibial amputees","authors":"Nimet Sermenli Aydın, İlke Kurt, Halit Selçuk, Sinem Salar, Sezer Ulukaya, Hilal Keklicek","doi":"10.1016/j.gaitpost.2023.07.229","DOIUrl":"https://doi.org/10.1016/j.gaitpost.2023.07.229","url":null,"abstract":"Gait adaptation to perturbations is essential for safe interaction with the physical environment and therefore it is important to understand how people with lower-limb amputation adapt their gait to changing conditions (1). Previous studies tried to find some deviation patterns and understand the kinematic strategies of amputee's gait (2). However, there is limited information available on the hip kinematics of amputees during gait and there is no study has yet investigated the effect of the perturbation on the hip kinematics of amputees. How does unpredictable continuous perturbation during gait affect the hip kinematics of unilateral transtibial amputees? Individuals with unilateral trans-tibial amputations and using prostheses with an active vacuum plus carbon foot combination were included in to study. Kinematic data of the hip were collected from 11 amputees and 10 healthy controls during walking on two different ground conditions. Participants walked at least 512 steps at their preferred speed on a motorized treadmill’s (ReaxRun Pro) flat ground condition and then the gait analysis was repeated on a perturbed (5% unpredictable perturbation) ground condition. RehaGait- Pro system was used for evaluation of the kinematics of the hip(min-max hip angles and variability of the hip min-max angles) during gait. Negative values indicated hip hyperextension, positive values indicated hip flexion. The statistical analysis was performed by pairing the residual limbs of amputees with the non-dominant side of the healthy group (RL side), and the sound limbs with the dominant side of the healthy group (HL side). It was observed that the hip hyperextension angle on the sound limb side was bigger in the amputees than in the control group on flat (d=0.462; p=0.034) and perturbated ground (d=0.584; p=0.007). The effect size was larger on the perturbed ground. There was no difference in the maximum hip angles and variability of max-min hip angles between the groups in both ground conditions (p>0.05). The results showed in Table.Download : Download high-res image (142KB)Download : Download full-size image Amputation-related changes were observed in hip kinematics during walking under both ground conditions. However, this change was more prominent on the perturbated ground. The reason for the higher hip hyperextension values in amputees is thought to be due to their efforts to compensate for the ankle (exp. strong plantar flexion) movements. On the unpredictable perturbation ground, the limitation of ankle movements, which is one of the first adaptive mechanisms in adaptation to the ground (exp. subtalar rotations plus plantarflexion), may have made the situation more evident. Future studies may focus on the effect of gait training on perturbed surfaces on gait kinematics, which is an indicator of adaptation to variable conditions.","PeriodicalId":94018,"journal":{"name":"Gait & posture","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135297885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Gait & posture
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1