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Impact of eating window and diet composition on obesity: a comparative study of adults in the USA and South Korea. 饮食窗口和饮食构成对肥胖的影响:美国和韩国成年人的比较研究。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf089
Li-Juan Tan, Jialei Fu, Sangah Shin

Background: Dietary habits influence weight management and metabolic health. This study examined trends in eating window and diet composition, and their correlation with obesity among adults.

Methods: Data from the U.S. National Health and Nutrition Examination Surveys (NHANES) and South Korea's Korean National Health and Nutrition Examination Survey (KNHANES) (2007-2020) were analyzed. The study assessed eating window, diet composition, and obesity. The eating window was defined from the first energy intake after waking up to the last before bed. Diet composition was linked to respective national food databases.

Results: Both countries saw increased snack consumption and body mass index (BMI) over 14 years. Korean adults showed the lowest obesity rates with an 8-9 hour eating window, while U.S. adults had the lowest rates with an 8-11 hour window. Macronutrient analysis revealed Korean breakfasts were carbohydrate-rich, while dinners included higher protein and alcohol intake.

Conclusions: Koreans have shorter eating windows and lower BMI than U.S. adults. This suggests the potential benefits of time-restricted eating but highlights the need for personalized interventions and further research on individual, cultural, and environmental factors.

背景:饮食习惯影响体重管理和代谢健康。这项研究调查了成年人饮食窗口和饮食构成的趋势,以及它们与肥胖的关系。方法:分析美国国家健康与营养检查调查(NHANES)和韩国国家健康与营养检查调查(KNHANES)(2007-2020)的数据。该研究评估了饮食窗口、饮食构成和肥胖。进食窗口是从醒来后的第一次能量摄入到睡觉前的最后一次能量摄入。饮食组成与各自的国家食品数据库相关联。结果:14年来,这两个国家的零食消费量和体重指数(BMI)都有所增加。韩国成年人的肥胖率以8-9小时为限,而美国成年人的肥胖率以8-11小时为限。宏量营养素分析显示,韩国早餐富含碳水化合物,而晚餐则含有较高的蛋白质和酒精摄入量。结论:韩国人的进食时间比美国人短,身体质量指数也比美国人低。这表明了限时饮食的潜在好处,但也强调了个性化干预和对个人、文化和环境因素的进一步研究的必要性。
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引用次数: 0
Understanding the social burden of multiple sclerosis patients in Georgia: a comprehensive analysis of quality of life and sociodemographic factors. 了解格鲁吉亚多发性硬化症患者的社会负担:对生活质量和社会人口因素的综合分析。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf018
Natalia Khutsishvili, Nino Ganugrava, Marina Janelidze, Tamar Vashadze, Marina Kiziria, Marika Megrelishvili, Alexander Tsiskaridze

Background and objectives: Multiple sclerosis (MS) is a chronic autoimmune disorder that significantly impacts individuals' quality of life and imposes a substantial social burden on patients and society. Despite its global socioeconomic implications, limited research has focused on the social burden of MS. This study aimed to assess the social burden of MS in Georgia by evaluating the health-related quality of life of MS patients and exploring the correlation between disease burden and quality of life.

Methodology: This cross-sectional study was performed to assess the social burden of the disease by evaluating the impact of the disease on the quality of life of 384 patients with MS. The Multiple Sclerosis Quality of Life-54 questionnaire was administered to assess quality of life.

Results: The Expanded Disability Status Scale score was significantly negatively correlated with the physical health composite score (r = -0.249, P < .001) and the general quality of life score (r = -0.220, P < .001). The quality of life was highly associated with gender, employment status, living/residence place, and moderately with age.

Conclusions and implications: This study revealed the intricate interplay between disability, quality of life, and sociodemographic factors among Georgian MS patients. The results of the study highlight the need for specialized therapies, networks of support, and public health initiatives to lessen the societal cost of MS.

背景与目的:多发性硬化症(MS)是一种慢性自身免疫性疾病,严重影响个体的生活质量,给患者和社会带来沉重的社会负担。尽管其具有全球社会经济意义,但有限的研究集中在MS的社会负担上。本研究旨在通过评估MS患者与健康相关的生活质量来评估格鲁吉亚MS的社会负担,并探讨疾病负担与生活质量之间的相关性。方法:本横断面研究通过评估疾病对384例ms患者生活质量的影响来评估疾病的社会负担。采用多发性硬化症生活质量问卷(Multiple Sclerosis quality of life -54)评估生活质量。结果:扩展残疾状态量表得分与身体健康综合得分呈显著负相关(r = -0.249, P)。结论和意义:本研究揭示了格鲁吉亚多发性硬化症患者残疾、生活质量和社会人口学因素之间复杂的相互作用。研究结果强调需要专门的治疗方法、支持网络和公共卫生倡议来减少MS的社会成本。
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引用次数: 0
Effects of the COVID-19 pandemic and 'Find Cancer Early' campaign on cancer symptom knowledge in regional Western Australia. COVID-19大流行和“早期发现癌症”运动对西澳大利亚地区癌症症状知识的影响。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf083
Ying Ru Feng, Derrick Lopez, Sarah V Ward, Cassandra Clayforth, Clover Maitland, Hussam Al-Hakimi, Melissa Ledger, Elizabeth Sorial, David B Preen

Background: Awareness of cancer and its symptoms may have declined in 2020 following the onset of the COVID-19 pandemic. We examined the effect of the COVID-19 pandemic and awareness of the 'Find Cancer Early' mass media campaign on the knowledge of common cancer symptoms in regional Western Australian (WA) residents aged 40 years and over.

Methods: Campaign materials from 'Find Cancer Early' included the 'Rural Doctors' video advertisement and the 'Yellow Checklist'. Multivariable log-binomial regression analyses were undertaken using data from the annual post-campaign evaluations surveys between 2018 and 2020, which included information on campaign awareness, cancer symptom knowledge, and sociodemographic factors.

Results: The number of cancer symptoms recalled (mean (M): 1.32 vs 1.72; P < .001) and the proportion of participants with better cancer symptom knowledge (16.9% vs 25.7%; P < .001) were lower in 2020 than the pre-pandemic time-period. Campaign awareness (prevalence ratio (PR) = 1.99; P < .001) and females (PR = 1.28; P = .002) were associated with better cancer symptom knowledge, while the pandemic time-period (PR = 0.59; P < .001), older age (PR = 0.57; P < .001), and a previous cancer diagnosis (PR = 0.76; P = .007) were associated with poorer knowledge.

Conclusions: Despite the ongoing pandemic, campaign awareness was associated with better knowledge of common cancer symptoms in regional WA. Regional subpopulations, including males and older adults, should be targeted for future campaigns.

背景:在2019冠状病毒病大流行爆发后,2020年人们对癌症及其症状的认识可能有所下降。我们研究了COVID-19大流行和“早期发现癌症”大众媒体运动对西澳大利亚州40岁及以上地区居民常见癌症症状知识的影响。方法:“早期发现癌症”的宣传材料包括“乡村医生”视频广告和“黄色清单”。使用2018年至2020年年度竞选后评估调查的数据进行多变量对数二项回归分析,其中包括竞选意识、癌症症状知识和社会人口因素的信息。结果:癌症症状回忆次数(平均(M): 1.32 vs 1.72;结论:尽管正在发生大流行,但在西澳大利亚地区,提高宣传意识与更好地了解常见癌症症状有关。区域亚人群,包括男性和老年人,应成为未来运动的目标。
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引用次数: 0
Where do adults see alcohol marketing? Insight from a cross-sectional survey in the United Kingdom. 成年人如何看待酒类营销?来自英国横断面调查的见解。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf118
Nathan Critchlow, Anne Marie MacKintosh, Allison Ford

Background: There is limited insight about the reach of alcohol marketing among adults in the United Kingdom (UK). We therefore examined awareness across a range of marketing activities and sources and how this differed by degree of alcohol use.

Method: An online cross-sectional survey with a nonprobability adult sample (18+) in the UK (n = 6021). Participants self-reported past-month awareness of alcohol marketing and special price deals from companies/brands, off-trade shops (e.g. supermarkets), online retailers, and on-trade venues (e.g. pubs/bars). Alcohol use was assessed using the AUDIT-C (coded: nondrinkers, lower-risk drinkers, higher-risk drinkers, not stated).

Results: For alcohol companies/brands, 65.9% had seen advertising (e.g. on TV) and 79.5% had seen wider marketing (e.g. sponsorship). For off-trade shops, 86.8% had seen marketing (e.g. product displays) and 76.6% had seen special price deals (e.g. multi-buy discounts). For online retailers, 30.8% had seen marketing (e.g. leaflets/flyers) and 52.4% had seen special price offers. For on-trade venues, 69.0% had seen marketing (e.g. posters/leaflets/flyers) and 52.1% had seen special price offers. The odds of reporting awareness were generally lower among nondrinkers and higher among higher-risk drinkers (vs. lower-risk).

Conclusion: Adults see alcohol marketing through various activities and sources, with awareness generally increasing with degree of alcohol use.

背景:关于英国成人酒精营销的影响范围的见解有限。因此,我们研究了一系列营销活动和来源的意识,以及这种意识如何因酒精使用程度而不同。方法:在英国对非概率成人样本(18岁以上)进行在线横断面调查(n = 6021)。参与者自我报告了过去一个月对酒类营销和来自公司/品牌、场外商店(如超市)、在线零售商和场内场所(如酒吧/酒吧)的特价优惠的了解程度。使用AUDIT-C评估酒精使用情况(编码:不饮酒者、低风险饮酒者、高风险饮酒者,未说明)。结果:对于酒类公司/品牌,65.9%的人看到过广告(如电视),79.5%的人看到过更广泛的营销(如赞助)。对于非交易商店,86.8%的人看到了市场营销(例如产品展示),76.6%的人看到了特价交易(例如多次购买折扣)。在网上零售商中,30.8%的人看到过促销活动(例如传单/传单),52.4%的人看到过特价。在业内场地,69.0%的场地看到了市场推广(例如海报/单张/传单),52.1%的场地看到了特价优惠。一般来说,不饮酒者报告意识的几率较低,而高风险饮酒者报告意识的几率较高(相对于低风险)。结论:成年人通过各种活动和渠道看到酒精营销,随着酒精使用程度的提高,意识普遍增强。
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引用次数: 0
Can workplace charters reduce health inequalities for employees: a qualitive analysis of employer interviews in West Yorkshire, England. 工作场所特许能减少雇员的健康不平等吗:对英国西约克郡雇主访谈的定性分析。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf072
Sulia Celebi

Background: Increasing the number of good quality jobs is a priority to reduce widening health inequalities. In England, workplace charters are becoming increasingly popular; however, there is limited knowledge on how this intervention works. This study explored employers' perspectives of workplace charters to understand the potential for charters to reduce health inequalities for employees.

Methods: Semi-structured qualitative interviews were conducted with 12 employers in West Yorkshire, England between August and September 2022. Employers were purposively recruited. Interviews were analysed using reflexive thematic analysis.

Results: Employers perceived charters to improve workplace practices by providing a benchmark; facilitating a business community; opening a dialogue with partners; and being a credible badge for fair employers. Using a social determinants of health framework, a novel logic model was developed from these mechanisms, illustrating how charters can reduce health inequalities. Key emergent barriers to charter effectiveness were also identified.

Conclusions: This study has identified that employers' perceptions of workplace charters support the view that charters can reduce health inequalities. However, emergent barriers to charter effectiveness highlighted that charters could equally generate inequalities by excluding organisations. If policy makers reconcile this tension, workplace charters could potentially be a timely and meaningful intervention to reduce health inequalities.

背景:增加高质量工作的数量是减少日益扩大的卫生不平等的优先事项。在英国,工作场所特许正变得越来越受欢迎;然而,关于这种干预如何起作用的知识有限。本研究探讨了雇主对工作场所章程的看法,以了解章程在减少雇员健康不平等方面的潜力。方法:于2022年8月至9月对英国西约克郡的12名雇主进行半结构化定性访谈。雇主是有目的地被招募的。访谈采用反身性专题分析进行分析。结果:雇主认为章程通过提供基准来改善工作场所的做法;促进商界的发展;与合作伙伴开展对话;成为公平雇主的可靠标志。利用健康的社会决定因素框架,从这些机制中开发了一个新的逻辑模型,说明了宪章如何能够减少健康不平等。还确定了影响包机效力的主要新障碍。结论:本研究已经确定,雇主对工作场所章程的看法支持了章程可以减少健康不平等的观点。然而,宪章效力面临的新障碍突出表明,宪章排除组织也可能产生不平等。如果政策制定者能够调和这种紧张关系,工作场所特许可能成为减少健康不平等的及时而有意义的干预措施。
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引用次数: 0
Rural-urban differences in healthcare utilization across different outcomes in Portugal. 葡萄牙不同结果的城乡医疗保健利用差异。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf123
Júlia Martinho, Andreia Leite

Background: Urbanization influences healthcare access and utilization, contributing to health disparities. This study aims to assess the effect of degree of urbanization on healthcare utilization in Portugal, where urbanization levels are above global average.

Methods: Utilizing data from the 2019 National Health Survey, this cross-sectional study analyzed the association between degree of urbanization and outcomes including general and specialist consultations, flu vaccination, colonoscopy, and wait times. Adjusted prevalence ratios (aPR) were estimated using Poisson regression models.

Results: Less populated areas had increased wait times (aPR = 1.54; 95% confidence intervals [95% CI]: 1.06-2.24) and lower colonoscopy utilization (aPR = 0.86; 95% CI: 0.78-0.95). Flu vaccination rates were higher in rural (aPR = 1.15; 95% CI: 1.03-1.30) and suburban areas (aPR = 1.16; 95% CI: 1.04-1.30). No significant association was found for general/specialist consultations or excessive wait times.

Conclusions: Geographic constraints limit healthcare access in less populated areas. Urban areas showed suboptimal flu vaccination rates, suggesting a need for improved immunization strategies. Addressing geographical disparities is crucial for ensuring equitable healthcare access across Portugal.

背景:城市化影响医疗服务的获取和利用,导致健康差异。本研究旨在评估城市化程度对葡萄牙医疗保健利用的影响,葡萄牙的城市化水平高于全球平均水平。方法:利用2019年全国健康调查的数据,这项横断面研究分析了城市化程度与结果之间的关系,包括普通和专科咨询、流感疫苗接种、结肠镜检查和等待时间。校正患病率(aPR)采用泊松回归模型估计。结果:人口较少地区的等待时间增加(aPR = 1.54; 95%可信区间[95% CI]: 1.06-2.24),结肠镜使用率较低(aPR = 0.86; 95% CI: 0.78-0.95)。流感疫苗接种率在农村(aPR = 1.15; 95% CI: 1.03-1.30)和郊区(aPR = 1.16; 95% CI: 1.04-1.30)较高。没有发现与普通/专家咨询或过度等待时间有显著关联。结论:地理限制限制了人口较少地区的医疗服务可及性。城市地区的流感疫苗接种率并不理想,这表明需要改进免疫策略。解决地域差异对于确保葡萄牙各地公平获得医疗保健至关重要。
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引用次数: 0
Patient and public involvement in a randomized study: a qualitative study of participants' experiences in a Mediterranean Diet trial. 患者和公众参与一项随机研究:地中海饮食试验中参与者经历的定性研究。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf108
Naomi Cano-Ibáñez, Virginia Martínez-Ruiz, Carmen Amezcua-Prieto, Amira Bouzalmate-Hajjaj, Aurora Bueno-Cavanillas, Paloma Masso-Guijarro

Background: Randomized clinical trials (RCTs) based on Mediterranean Diet (MedDiet) have reported that higher adherence is associated with better health outcomes. Our aim was to describe the perspectives and experiences of older adults in a MedDiet RCT for cardiovascular disease prevention.

Methods: Three focus groups on 25 participants from a MedDiet RCT, aged from 63 to 76 years old, were conducted after a conference on patient and public involvement in research at the University of Granada (Spain). Each focus group, comprising 8-10 participants, was audio-recorded, transcribed, and thematically analysed.

Results: Participants were motivated by research team commitment during follow-up, improved health status and chronic disease management, weight loss, and enhanced health literacy. Health benefits among cohabitants were highlighted by female participants. A more personalized counselling and transparency with disclosure of the results of their tests and on-going study findings were missed. Participants were willing to collaborate in the dissemination of findings. Involving patients in RCTs would align the interventions with their needs and health conditions.

Conclusion: In the context of an RCT, participants could join the research team, identifying key questions, planning study design, contributing to the intervention protocol, and helping disseminate results by selecting the best platforms for sharing findings.

背景:基于地中海饮食(MedDiet)的随机临床试验(rct)已经报道,更高的依从性与更好的健康结果相关。我们的目的是描述MedDiet随机对照试验中老年人预防心血管疾病的观点和经验。方法:在西班牙格拉纳达大学(University of Granada)举行的患者和公众参与研究会议后,对来自MedDiet随机对照试验的25名参与者进行了三个焦点小组,年龄从63岁到76岁。每个焦点小组由8-10名参与者组成,录音、转录并进行主题分析。结果:参与者在随访期间受到研究团队承诺的激励,健康状况和慢性疾病管理得到改善,体重减轻,健康素养得到提高。女性参与者强调了同居者的健康益处。他们错过了更加个性化的咨询和透明度,披露了他们的测试结果和正在进行的研究结果。与会者愿意在传播调查结果方面进行合作。让患者参与随机对照试验将使干预措施与他们的需求和健康状况保持一致。结论:在随机对照试验的背景下,参与者可以加入研究团队,确定关键问题,规划研究设计,参与干预方案,并通过选择最佳平台来分享结果,帮助传播结果。
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引用次数: 0
The effects of the COVID-19 pandemic on wellbeing up to 2.5 years from its outbreak in Switzerland. 2019冠状病毒病大流行在瑞士爆发2.5年后对健康的影响。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf107
Dawid Gondek, Marieke Voorpostel, Núria Sánchez-Mira, Teuta Mehmeti

Background: This article examined to what extent pandemic-related exposures were associated with negative affect up to 2.5 years from the outbreak of the pandemic in Switzerland.

Methods: We drew on longitudinal data from five waves (2018-22) of the Swiss Household Panel, including the pandemic questionnaire collected in May-June 2020 (n = 5657). Our outcome, negative affect (e.g. frequency of negative emotions such as anxiety or sadness), was measured in 2020, 2021, and 2022.

Results: Our study showed that a higher frequency of psychosomatic symptoms (e.g. sweating), greater worries (e.g. lifestyle), and concerns about perceived financial risk were strongly and persistently associated with higher negative affect up to 2.5 years after the outbreak of the pandemic. Worsened relationships with neighbours and a deteriorated financial situation were associated with higher negative affect during the pandemic, but not postpandemic. Finally, an increase in physical activity (but not an absolute frequency of exercising) was linked to lower negative affect in the short-term.

Conclusion: The findings emphasize the importance of mitigating pandemic-related worries and stress, as these can have long-lasting postcrisis consequences on people's wellbeing. Moreover, preventing a decline in the financial situation and relationships within the community as well as adopting a healthy lifestyle may have protective effects.

Highlights:

背景:本文研究了与大流行相关的暴露在多大程度上与瑞士大流行爆发2.5年后的负面影响相关。方法:我们利用瑞士家庭小组五波(2018-22)的纵向数据,包括2020年5月至6月收集的大流行问卷(n = 5657)。我们的结果,负面影响(例如焦虑或悲伤等负面情绪的频率),在2020年、2021年和2022年进行了测量。结果:我们的研究表明,心身症状(如出汗)、更大的担忧(如生活方式)和对感知到的财务风险的担忧的频率较高,与大流行爆发后2.5年的较高负面影响密切相关。大流行期间,与邻国关系恶化和财政状况恶化与较高的负面影响有关,但大流行后则不然。最后,体育活动的增加(但不是运动的绝对频率)与短期内较低的负面影响有关。结论:研究结果强调了减轻与大流行相关的担忧和压力的重要性,因为这些担忧和压力可能对危机后人们的福祉产生长期影响。此外,防止财务状况和社区内关系的恶化以及采取健康的生活方式可能具有保护作用。亮点:
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引用次数: 0
Correction to: Clicks, likes, and mental strikes: the health industry's response to social media challenges. 更正:点击、点赞和精神打击:健康行业对社交媒体挑战的回应。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf119
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引用次数: 0
Potential influence of cancer history on mesothelioma incidence: an ecologic analysis in the U.S. population. 癌症病史对间皮瘤发病率的潜在影响:美国人群的生态学分析。
IF 3.1 Pub Date : 2025-12-01 DOI: 10.1093/pubmed/fdaf110
Callan F Krevanko, Ashley M Hernandez, Alison M Gauthier, Moin S Vahora, Ryan C Lewis, Jennifer S Pierce

Background: There is a demand for population level research on the potential genetic-basis of mesothelioma (e.g. BRCA1-associated protein-1 [BAP1]) independent of other risk factors, such as amphibole asbestos exposure. By surrogate, another primary cancer history can be used to explore this issue, including in the USA, where the incidence rates (IRs) in men, but not women, are temporally aligned with historical asbestos consumption.

Methods: We computed age-adjusted IRs of mesothelioma in females and males stratified by other primary cancer history using publicly available U.S. cancer data from 1975 to 2021. To facilitate comparison with other cancers associated with BAP1, we calculated age-adjusted IRs for female breast cancer and melanoma.

Results: Similar to breast cancer and melanoma, ~ 25% of females with mesothelioma had a history of at least one other primary cancer. While IRs of mesothelioma in males without a history of other primary cancers were temporally aligned with historical asbestos consumption trends in the USA, IRs of mesothelioma among males with other primary cancer histories showed no relationship with asbestos consumption trends.

Conclusions: Our findings suggest that a genetic predisposition for malignancy contributes to U.S. mesothelioma rates and is a distinct risk factor independent of asbestos exposure.

背景:对于间皮瘤的潜在遗传基础(如brca1相关蛋白-1 [BAP1])的人群水平研究的需求独立于其他危险因素,如角洞石棉暴露。通过替代,可以使用另一种原发癌症史来探讨这一问题,包括在美国,男性的发病率(IRs)与历史石棉消费时间一致,而不是女性。方法:我们使用1975年至2021年美国公开的癌症数据,根据其他原发癌症病史,计算了年龄调整后的女性和男性间皮瘤的IRs。为了便于与其他与BAP1相关的癌症进行比较,我们计算了女性乳腺癌和黑色素瘤的年龄调整后的IRs。结果:与乳腺癌和黑色素瘤相似,约25%的间皮瘤女性患者有至少一种其他原发癌症病史。在美国,没有其他原发癌症病史的男性间皮瘤的ir与石棉消费趋势在时间上是一致的,而有其他原发癌症病史的男性间皮瘤的ir与石棉消费趋势没有关系。结论:我们的研究结果表明,恶性肿瘤的遗传易感性有助于美国间皮瘤的发病率,并且是独立于石棉暴露的一个明显的危险因素。
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引用次数: 0
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Journal of public health (Oxford, England)
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