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Lessons from the Department of Veterans Affairs: A continuum of age-friendly care for older adults. 退伍军人事务部的经验教训:为老年人提供持续的老年友好护理。
Pub Date : 2024-10-18 DOI: 10.1111/jgs.19228
Kimberly A Wozneak, Shivani K Jindal, Shannon Munro, Courtney A Huhn, Tonya Page, Thomas E Edes, Scotte R Hartronft

With almost 90% of Americans expressing a desire to age in place in their home, many health systems and communities are challenged to provide the right resources, at the right time, to support What Matters to older adults. In the Department of Veterans Affairs (VA), approximately 50% of Veterans enrolled in VA health care are aged 65 and older, driving an imperative to provide timely, Age-Friendly care through a broad continuum of services. VA has taken a multifaceted approach to shift Long-Term Services and Supports to promote aging in place through innovation pilots, expansion of Home and Community Based Services (HCBS) and adoption of Age-Friendly Health Systems (AFHS) practices [or "framework"]. VA is spreading geriatrics knowledge throughout the clinician and trainee workforce, improving skills and practices across all disciplines and care settings. The framework of AFHS creates a shared language to support transitions across ambulatory, hospital, emergency department, home care, and nursing home settings. Through these efforts, VA is reimagining geriatrics, providing an example of the type of care all older adults want and deserve. Since March 2020, 375 care settings across 132/139 (95%) VA parent facilities have earned AFHS recognition. By incorporating AFHS into the infrastructure of the healthcare system, clinicians are prepared to address What Matters across clinical settings and address common geriatric syndromes. Leaders in a variety of health systems can learn from VA efforts to provide a continuum of Age-Friendly programs and services that promote independence, function, well-being and aging in place.

近 90% 的美国人表示希望在家中安享晚年,许多医疗系统和社区都面临着在适当的时间提供适当的资源以支持老年人的重要事项的挑战。在退伍军人事务部(VA),约 50%接受退伍军人医疗保健服务的退伍军人年龄在 65 岁及以上,因此必须通过广泛的连续性服务提供及时、适合老年人的医疗保健服务。退伍军人事务部采取了多方面的方法来转变长期服务和支持,通过创新试点、扩大家庭和社区服务(HCBS)以及采用老龄友好医疗系统(AFHS)实践[或 "框架"]来促进居家养老。退伍军人事务部正在整个临床医生和受训人员队伍中传播老年医学知识,提高所有学科和护理环境的技能和实践。AFHS 框架创造了一种共享语言,以支持门诊、医院、急诊科、家庭护理和疗养院环境之间的过渡。通过这些努力,退伍军人事务部正在重新构想老年医学,为所有老年人想要和应该得到的护理类型提供了一个范例。自 2020 年 3 月以来,132/139(95%)个退伍军人事务部上级机构中的 375 个护理机构获得了 AFHS 认证。通过将 AFHS 纳入医疗保健系统的基础设施,临床医生已准备好在各种临床环境中处理 "重要事项",并应对常见的老年综合症。各种医疗系统的领导者都可以从退伍军人事务部的努力中汲取经验,以提供一系列 "爱老计划 "和服务,促进独立、功能、幸福和居家养老。
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引用次数: 0
Hierarchical endpoints analyzed using the win-ratio method as a practical innovation for deprescribing trials. 使用胜率法分析分层终点是去药方试验的一项实用创新。
Pub Date : 2024-10-17 DOI: 10.1111/jgs.19224
Parag Goyal, Samprit Banerjee, Michael A Steinman, Andrew P Ambrosy
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引用次数: 0
Predictors of advance care planning in 11 high-income nations. 11 个高收入国家预先护理规划的预测因素。
Pub Date : 2024-10-17 DOI: 10.1111/jgs.19226
Preshit N Ambade, Zachary T Hoffman, Kaamya Mehra, Neil J MacKinnon

Background: Elderly population is increasing in high-income countries. For instance, by 2050, 21.4% of the United States population is expected to be 65+, thus making advance care planning (ACP) increasingly important. We aim to identify predictors of ACP completion in 11 high-income countries and explore relationships between ACP and utilization factors.

Method: Using the 2021 International Health Policy (IHP) survey data, we assessed the relationship between sociodemographic factors, healthcare utilization, and ACP. The primary outcome variable was a composite of three ACP activities. A generalized linear mixed model (GLMM) was used to identify predictors of ACP completion.

Results: Analyses included 18,677 older adults who answered at least one ACP question. Only 5126 (27.4%) reported completion of three ACP activities. Germany (64.7%) showed the highest completion rates, while Sweden (5.0%) and France (5.0%) showed the lowest completion rates. Predictors of ACP completion identified in the GLMM were: increasing age (incidence rate ratio [IRR] range between 1.2 and 1.5), completion of high school education or more (IRR: 1.1, 95% CI: 1.1-1.1), higher income (IRR: 1.1, 95% CI: 1.1-1.2), presence of two or more health conditions (IRR: 1.1, 95% CI: 1.0-1.1), hospital stay in the past 2 years (IRR: 1.1, 95% CI: 1.1-1.1), and access to quality primary care (IRR: 1.0, 95% CI: 1.0-1.1). Male gender (IRR: 0.9, 95% CI: 0.8-0.9) had a negative association with ACP activity completion.

Conclusion: Several patient-specific and health system utilization factors were identified as predictors of ACP activity completion, which clinicians and policymakers could use to enhance ACP completion.

背景:在高收入国家,老年人口正在不断增加。例如,到 2050 年,美国 21.4% 的人口预计将达到 65 岁以上,这使得预先护理计划(ACP)变得越来越重要。我们旨在确定 11 个高收入国家完成 ACP 的预测因素,并探讨 ACP 与利用因素之间的关系:利用 2021 年国际卫生政策(IHP)调查数据,我们评估了社会人口因素、医疗保健利用率和 ACP 之间的关系。主要结果变量是 ACP 三项活动的综合结果。我们使用广义线性混合模型(GLMM)来确定完成 ACP 的预测因素:分析包括 18677 名至少回答了一个 ACP 问题的老年人。只有 5126 人(27.4%)报告完成了三项 ACP 活动。德国(64.7%)的完成率最高,而瑞典(5.0%)和法国(5.0%)的完成率最低。在 GLMM 中确定的完成 ACP 的预测因素有:年龄增加(发病率比 [IRR] 范围在 1.2 和 1.5 之间)、完成高中或以上教育(IRR:1.1,95% CI:1.1-1.1)、收入增加(IRR:1.1,95% CI:1.1-1.2)、有两种或两种以上健康状况(IRR:1.1,95% CI:1.0-1.1)、过去 2 年住院(IRR:1.1,95% CI:1.1-1.1)以及获得优质初级医疗服务(IRR:1.0,95% CI:1.0-1.1)。男性性别(IRR:0.9,95% CI:0.8-0.9)与完成 ACP 活动呈负相关:结论:几项患者特异性因素和医疗系统使用因素被认为是 ACP 活动完成度的预测因素,临床医生和政策制定者可以利用这些因素来提高 ACP 活动的完成度。
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引用次数: 0
A public health/hospital partnership to improve Emergency Department transitions of care for vulnerable older adults. 公共卫生与医院合作,改善急诊科对弱势老年人的过渡护理。
Pub Date : 2024-10-17 DOI: 10.1111/jgs.19227
Lauren T Southerland, Carolyn Dixon, Shameka Turner, Kalih M West, Tameka Hairston, Tony Rosen, Caroline Rankin

Background: Community-dwelling older adults are at high risk for unmet social service needs. We describe a novel partnership embedding county services case managers in the Emergency Department (ED) to connect older adults to community services alongside their medical care.

Methods: Setting: A medium-sized urban ED with 55,000 patient visits a year.

Intervention: Case managers from the Franklin County, Ohio Office on Aging (OA) were embedded within the ED. The OA team worked with the ED social work team to identify community-dwelling older patients, perform an in-person intake assessment, and initiate needed community services (including home-delivered meals, emergency response systems, house repairs, and transportation). Program logic model and development are reported in detail.

Results: From June to December 2023, there were 7284 ED visits for adults ≥60 years old. Referrals to the OA case manager ranged from 1 to 13 per day. The OA case managers performed 252 full intake assessments on unique patients. The population was 51% men. Only 11% (n = 28) were currently connected to OA services, and of those already connected 29% (n = 8) needed increased services. Of the remaining unconnected patients (n = 224), 8% (n = 20) were not county residents and the OA team connected them with other county OAs. Half 53% (n = 120) were accepting of services and had services from the OA or other community health programs initiated during the ED visit. The OA team made three new Adult Protective Services referrals and one referral to the long-term care ombudsman. The program did not increase ED length of stay or hospital admission rates.

Conclusions: Embedding county service enrollment within a community ED is a cost neutral intervention that reached a population without previous services. Future plans include expansion of the program and evaluation of the program's ability to detect elder mistreatment and self-neglect.

背景:居住在社区的老年人是社会服务需求得不到满足的高危人群。我们介绍了一种新颖的合作方式,即在急诊科(ED)中设置县级服务机构的个案经理,在为老年人提供医疗服务的同时,将他们与社区服务联系起来:环境:干预措施:干预措施:俄亥俄州富兰克林县老龄化办公室(OA)的个案经理被派驻到急诊科。OA 团队与急诊室社工团队合作,识别居住在社区的老年患者,进行上门入院评估,并启动所需的社区服务(包括送餐上门、应急响应系统、房屋维修和交通)。详细报告了计划逻辑模型和发展情况:从 2023 年 6 月到 12 月,≥60 岁的成年人共接受了 7284 次急诊室就诊。转介给 OA 个案经理的人数从每天 1 人到 13 人不等。OA 个案经理共对 252 名患者进行了全面的入院评估。其中 51% 为男性。目前只有 11%(n = 28)的患者获得了 OA 服务,而在已经获得 OA 服务的患者中,29%(n = 8)的患者需要更多服务。在其余未连接的患者(n = 224)中,8%(n = 20)不是本县居民,OA 小组将他们连接到了本县其他 OA。半数 53%(n = 120)的患者接受了服务,并在急诊室就诊期间接受了 OA 或其他社区健康计划提供的服务。OA 小组新转介了 3 名成人保护服务人员和 1 名长期护理监察员。该计划并未增加急诊室的住院时间或入院率:在社区急诊室内嵌入县级服务登记是一项成本中立的干预措施,可惠及以前未接受过服务的人群。未来的计划包括扩展该计划并评估该计划检测虐待老人和自我忽视的能力。
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引用次数: 0
Experiences of older surgical patients and care partners during COVID-19: Lessons for future care. 老年手术患者和护理伙伴在 COVID-19 期间的经历:对未来护理的启示。
Pub Date : 2024-10-16 DOI: 10.1111/jgs.19212
Mark Iskandar, C Ann Vitous, Lillian Min, Pasithorn A Suwanabol, Alexandra Norcott
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引用次数: 0
Comparison of targeted web-based advertising versus traditional methods for recruiting older adults into clinical trials. 在招募老年人参与临床试验方面,基于网络的定向广告与传统方法的比较。
Pub Date : 2024-10-16 DOI: 10.1111/jgs.19225
Kathryn Baldyga, Ike Iloputaife, George Taffet, Nicole LaGanke, Brad Manor, Lewis A Lipsitz, Courtney L Millar

Background: Recruiting older adults into clinical trials can be particularly challenging. Our objective was to determine if targeted web-based advertising is an effective recruitment strategy.

Methods: We compared the recruitment rates of traditional and targeted web-based methods for three representative clinical trials involving older adults. All studies utilized traditional recruitment methods initially, but shifted toward primarily targeted web-based advertising after experiencing slow recruitment rates.

Results: We found that web-based advertising reached more individuals compared to traditional methods. Compared to traditional methods, web-based methods also had at least twice the rate of expressed interest, completion of telephone and in-person screening, eligibility, and enrollment. Additionally, the proportion of individuals excluded after the telephone screening did not differ according to whether targeted web-based advertising (STAMINA: 51%; Berries and Steps: 62%; ISTIM: 20%) or traditional methods (STAMINA: 48%; Berries and Steps: 69%; ISTIM: 23%) were used within each study. Those recruited using web-based advertisements tended to be younger compared to traditional methods, but were similar in racial distribution and education.

Conclusion: Targeted web-based advertisements may be more effective in recruiting older adults for clinical trials at a faster rate than traditional recruitment methods, but need further evaluation of compatible study designs, potential population bias, and cost-effectiveness.

背景:招募老年人参与临床试验尤其具有挑战性。我们的目的是确定有针对性的网络广告是否是一种有效的招募策略:我们比较了三项有代表性的涉及老年人的临床试验中传统方法和有针对性的网络方法的招募率。所有研究最初都采用了传统的招募方法,但在经历了缓慢的招募率之后,主要转向了有针对性的网络广告:结果:我们发现,与传统方法相比,网络广告的受众更多。与传统方法相比,基于网络的方法在表达兴趣、完成电话和面对面筛选、资格审查和注册方面的比率也至少是传统方法的两倍。此外,电话筛查后被排除在外的人员比例并没有因每项研究中使用了有针对性的网络广告(STAMINA:51%;Berry and Steps:62%;ISTIM:20%)还是传统方法(STAMINA:48%;Berry and Steps:69%;ISTIM:23%)而有所不同。与传统方法相比,使用网络广告招募到的人往往更年轻,但在种族分布和教育程度方面相似:与传统招募方法相比,有针对性的网络广告在招募老年人参与临床试验方面可能更有效,但还需要进一步评估研究设计的兼容性、潜在的人群偏差以及成本效益。
{"title":"Comparison of targeted web-based advertising versus traditional methods for recruiting older adults into clinical trials.","authors":"Kathryn Baldyga, Ike Iloputaife, George Taffet, Nicole LaGanke, Brad Manor, Lewis A Lipsitz, Courtney L Millar","doi":"10.1111/jgs.19225","DOIUrl":"https://doi.org/10.1111/jgs.19225","url":null,"abstract":"<p><strong>Background: </strong>Recruiting older adults into clinical trials can be particularly challenging. Our objective was to determine if targeted web-based advertising is an effective recruitment strategy.</p><p><strong>Methods: </strong>We compared the recruitment rates of traditional and targeted web-based methods for three representative clinical trials involving older adults. All studies utilized traditional recruitment methods initially, but shifted toward primarily targeted web-based advertising after experiencing slow recruitment rates.</p><p><strong>Results: </strong>We found that web-based advertising reached more individuals compared to traditional methods. Compared to traditional methods, web-based methods also had at least twice the rate of expressed interest, completion of telephone and in-person screening, eligibility, and enrollment. Additionally, the proportion of individuals excluded after the telephone screening did not differ according to whether targeted web-based advertising (STAMINA: 51%; Berries and Steps: 62%; ISTIM: 20%) or traditional methods (STAMINA: 48%; Berries and Steps: 69%; ISTIM: 23%) were used within each study. Those recruited using web-based advertisements tended to be younger compared to traditional methods, but were similar in racial distribution and education.</p><p><strong>Conclusion: </strong>Targeted web-based advertisements may be more effective in recruiting older adults for clinical trials at a faster rate than traditional recruitment methods, but need further evaluation of compatible study designs, potential population bias, and cost-effectiveness.</p>","PeriodicalId":94112,"journal":{"name":"Journal of the American Geriatrics Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mary Poppins: A cinematic phenomenological exploration of life-course journey and inter-generational connections. 玛丽-波平斯对生命历程和代际联系的电影现象学探索。
Pub Date : 2024-10-14 DOI: 10.1111/jgs.19231
Hermine Lenoir
{"title":"Mary Poppins: A cinematic phenomenological exploration of life-course journey and inter-generational connections.","authors":"Hermine Lenoir","doi":"10.1111/jgs.19231","DOIUrl":"https://doi.org/10.1111/jgs.19231","url":null,"abstract":"","PeriodicalId":94112,"journal":{"name":"Journal of the American Geriatrics Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physician-reported barriers and facilitators to thyroid hormone deprescribing in older adults. 医生报告的老年人停用甲状腺激素的障碍和促进因素。
Pub Date : 2024-10-11 DOI: 10.1111/jgs.19219
Brandon Moretti, Rachel Livecchi, Stephanie R Taylor, Susan C Pitt, Brittany L Gay, Megan R Haymart, Arti Bhan, Jennifer Perkins, Maria Papaleontiou

Background: Thyroid hormone is one of the most commonly prescribed medications in the United States. Misuse of and overtreatment with thyroid hormone is common in older adults and can lead to cardiovascular and skeletal adverse events. Even though deprescribing can reduce inappropriate care, no studies have yet explored specific barriers and facilitators to guide thyroid hormone deprescribing in older adults (defined as discontinuation of thyroid hormone when initiated without an appropriate indication or dose reduction in those overtreated).

Methods: We conducted semi-structured interviews with 19 endocrinologists, geriatricians, and primary care physicians who prescribe thyroid hormone. Interviews were completed between July 2020 and December 2021 via two-way video conferencing. We used both an inductive and deductive content analysis guided by the Theoretical Domains Framework to evaluate transcribed and coded participant responses. Thematic analysis characterized themes related to barriers and facilitators to thyroid hormone deprescribing practices in older adults.

Results: The most commonly reported barriers to thyroid hormone deprescribing were related to patient-level factors, followed by physician- and system-level factors. Patient factors included patients' perceived need for thyroid hormone use and patient anxiety/concerns about potential side effects related to thyroid hormone dose reduction, patient lack of knowledge, and misinformation regarding deprescribing. Physician- and system-level barriers included clinic visit time constraints, physician inertia, physician lack of knowledge about deprescribing, perceived lack of sufficient patient follow-up, and electronic health record limitations. The most prominent physician-reported facilitators to thyroid hormone deprescribing were effective physician-to-patient communication, and positive physician-patient relationship, including patients' trust in their treating physician.

Conclusion: Barriers and facilitators to thyroid hormone deprescribing in older adults were reported at multiple levels including patient-, physician-, and system-level factors. Interventions to improve thyroid hormone deprescribing in older adults should aim to improve patient education and expectations, increase multidisciplinary physician awareness, and overcome physician inertia.

背景:甲状腺激素是美国最常用的处方药之一:甲状腺激素是美国最常用的处方药之一。甲状腺激素的滥用和过度治疗在老年人中很常见,可导致心血管和骨骼不良事件。尽管停用甲状腺激素可以减少不适当的治疗,但目前还没有研究探讨指导老年人停用甲状腺激素的具体障碍和促进因素(指在没有适当适应症的情况下停用甲状腺激素,或在过度治疗的情况下减少剂量):我们对 19 名开具甲状腺激素处方的内分泌科医生、老年病科医生和初级保健医生进行了半结构化访谈。访谈于 2020 年 7 月至 2021 年 12 月期间通过双向视频会议完成。在理论领域框架的指导下,我们采用了归纳和演绎内容分析的方法来评估转录和编码的参与者回答。主题分析描述了与老年人甲状腺激素处方障碍和促进因素相关的主题:最常报告的甲状腺激素处方障碍与患者层面的因素有关,其次是医生和系统层面的因素。患者因素包括患者对使用甲状腺激素的需求感知、患者对甲状腺激素剂量减少可能产生的副作用的焦虑/担忧、患者缺乏相关知识以及有关停药的错误信息。医生和系统层面的障碍包括门诊时间限制、医生惰性、医生对减量用药缺乏了解、认为缺乏足够的患者随访以及电子健康记录的限制。在医生的报告中,甲状腺激素处方最主要的促进因素是医生与患者之间的有效沟通以及积极的医患关系,包括患者对主治医生的信任:老年人停用甲状腺激素的障碍和促进因素涉及多个层面,包括患者、医生和系统层面的因素。改善老年人甲状腺激素处方的干预措施应着眼于改善对患者的教育和期望,提高多学科医生的认识,并克服医生的惰性。
{"title":"Physician-reported barriers and facilitators to thyroid hormone deprescribing in older adults.","authors":"Brandon Moretti, Rachel Livecchi, Stephanie R Taylor, Susan C Pitt, Brittany L Gay, Megan R Haymart, Arti Bhan, Jennifer Perkins, Maria Papaleontiou","doi":"10.1111/jgs.19219","DOIUrl":"https://doi.org/10.1111/jgs.19219","url":null,"abstract":"<p><strong>Background: </strong>Thyroid hormone is one of the most commonly prescribed medications in the United States. Misuse of and overtreatment with thyroid hormone is common in older adults and can lead to cardiovascular and skeletal adverse events. Even though deprescribing can reduce inappropriate care, no studies have yet explored specific barriers and facilitators to guide thyroid hormone deprescribing in older adults (defined as discontinuation of thyroid hormone when initiated without an appropriate indication or dose reduction in those overtreated).</p><p><strong>Methods: </strong>We conducted semi-structured interviews with 19 endocrinologists, geriatricians, and primary care physicians who prescribe thyroid hormone. Interviews were completed between July 2020 and December 2021 via two-way video conferencing. We used both an inductive and deductive content analysis guided by the Theoretical Domains Framework to evaluate transcribed and coded participant responses. Thematic analysis characterized themes related to barriers and facilitators to thyroid hormone deprescribing practices in older adults.</p><p><strong>Results: </strong>The most commonly reported barriers to thyroid hormone deprescribing were related to patient-level factors, followed by physician- and system-level factors. Patient factors included patients' perceived need for thyroid hormone use and patient anxiety/concerns about potential side effects related to thyroid hormone dose reduction, patient lack of knowledge, and misinformation regarding deprescribing. Physician- and system-level barriers included clinic visit time constraints, physician inertia, physician lack of knowledge about deprescribing, perceived lack of sufficient patient follow-up, and electronic health record limitations. The most prominent physician-reported facilitators to thyroid hormone deprescribing were effective physician-to-patient communication, and positive physician-patient relationship, including patients' trust in their treating physician.</p><p><strong>Conclusion: </strong>Barriers and facilitators to thyroid hormone deprescribing in older adults were reported at multiple levels including patient-, physician-, and system-level factors. Interventions to improve thyroid hormone deprescribing in older adults should aim to improve patient education and expectations, increase multidisciplinary physician awareness, and overcome physician inertia.</p>","PeriodicalId":94112,"journal":{"name":"Journal of the American Geriatrics Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142402476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of home-based isometric training on blood pressure in older adults with high normal BP or stage I hypertension: A randomized controlled trial. 家庭等长肌力训练对血压正常或 I 期高血压老年人血压的影响:随机对照试验。
Pub Date : 2024-10-11 DOI: 10.1111/jgs.19213
Diogo Pinto, Nuno Dias, Catarina Garcia, Manuel Teixeira, Maria J Marques, Teresa Amaral, Leonor Amaral, Ricardo Abreu, Daniela Figueiredo, Jorge Polónia, José Mesquita-Bastos, João L Viana, Linda S Pescatello, Fernando Ribeiro, Alberto J Alves

Objective: This trial analyzes the effects of home-based isometric handgrip training (IHT) and aerobic exercise training (AET) on ambulatory and office blood pressure (BP) in older adults with high normal to established hypertension.

Methods: This randomized controlled trial included 84 participants (46 women, 71.1 ± 3.6 years, systolic BP [SBP] 137.1 ± 13.8 mmHg, diastolic BP [DBP] 80.8 ± 8.3 mmHg). Participants were randomized into IHT (n = 28), AET (n = 28), or usual medical care plus lifestyle advice (UC, n = 28). Participants performed IHT or AET three times/week for 8 weeks. IHT consisted of 4 × 45 s bilateral contractions at 50% of maximum voluntary contraction with 1-min rest between sets. AET consisted of walking 30 min at 50%-70% of estimated maximum oxygen consumption. UC received standardized medical care including lifestyle advice.

Results: Seventy-six participants completed the intervention: 27 in IHT, 26 in AET, and 23 in UC. At baseline, BP values were similar among groups. No differences were observed in 24-h ambulatory, daytime, and nighttime SBP and DBP in any group (p > 0.05). IHT and AET reduced office SBP (-8.0 ± 13.4 mmHg; p = 0.004; -5.6 ± 12.2 mmHg; p = 0.027, respectively). IHT reduced office DBP (-3.3 ± 7.4 mmHg; p = 0.024), but AET did not. No differences occurred in office BP in UC. There was no difference in office BP among groups (p > 0.05).

Conclusions: An 8-week home-based IHT and AET failed to reduce ambulatory SBP, while office SBP was reduced by 8/5 mmHg. Only IHT reduced office DBP by 3 mmHg. Thus, IHT and AET may be effective for lowering office BP in older adults with high normal to established hypertension.

目的:本试验分析了在家进行的等长手握训练(IHT)和有氧运动训练(AET)对患有高血压的正常老年人的活动血压和办公室血压的影响:本试验分析了家庭等长手握训练(IHT)和有氧运动训练(AET)对高血压正常或已确诊的老年人活动血压和办公室血压(BP)的影响:这项随机对照试验包括 84 名参与者(46 名女性,71.1 ± 3.6 岁,收缩压 [SBP] 137.1 ± 13.8 mmHg,舒张压 [DBP] 80.8 ± 8.3 mmHg)。参与者被随机分为 IHT(28 人)、AET(28 人)或常规医疗护理加生活方式建议(UC,28 人)。参与者每周进行三次 IHT 或 AET,持续 8 周。IHT 包括 4 × 45 秒的双侧收缩,收缩量为最大自主收缩量的 50%,每组之间休息 1 分钟。AET包括以估计最大耗氧量的50%-70%步行30分钟。UC 接受标准化医疗护理,包括生活方式建议:结果:76 名参与者完成了干预:27 人参加了 IHT,26 人参加了 AET,23 人参加了 UC。各组基线血压值相似。各组 24 小时流动血压、白天和夜间 SBP 和 DBP 均无差异(P > 0.05)。IHT 和 AET 可降低办公室 SBP(分别为 -8.0 ± 13.4 mmHg; p = 0.004; -5.6 ± 12.2 mmHg; p = 0.027)。IHT 降低了办公室 DBP(-3.3 ± 7.4 mmHg;p = 0.024),但 AET 没有降低。UC 的办公室血压没有差异。各组间的办公室血压没有差异(p > 0.05):结论:为期 8 周的家庭 IHT 和 AET 未能降低流动 SBP,而办公室 SBP 则降低了 8/5 mmHg。只有 IHT 能将办公室 DBP 降低 3 mmHg。因此,IHT 和 AET 可有效降低高血压正常或已确诊的老年人的办公室血压。
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引用次数: 0
Neuropsychiatric presentations of common dementia syndromes: A concise review for primary care team members. 常见痴呆综合征的神经精神表现:面向初级医疗团队成员的简明综述。
Pub Date : 2024-10-10 DOI: 10.1111/jgs.19211
Zoë Bell, Maureen K O'Connor, Lauren R Moo

Dementia is a syndrome characterized by cognitive changes which interfere with daily functioning. Neuropsychiatric symptoms (NPS) are also pervasive and may even occur prior to any noticeable cognitive decline. Still, NPS are less associated with the early stages of the disease course, despite mounting research evidence that NPS present early and often in several dementia syndromes, even in the absence of cognitive decline (i.e., mild behavioral impairment [MBI]). Primary care teams are at the forefront of dementia care, yet they frequently report insufficient training in dementia diagnosis and management. This poses a serious problem considering that timely diagnosis of dementia is critical for optimal outcomes and maximum efficacy of intervention. We provide a concise narrative review of four dementia syndromes (Alzheimer's disease, vascular dementia, dementia with Lewy bodies, and behavioral variant frontotemporal dementia) and their associated neuropsychiatric presentations, as well as at-a-glance clinical guides, to help primary care team members recognize possible prodromal neurodegenerative disease and to prompt further workup. We also review next steps in the management of dementia and symptoms of MBI for primary care team members. As evidenced by the NPS profiles of these dementia syndromes, subacute new onset of psychiatric symptoms in an older adult should prompt consideration of an emerging dementia process and possible further workup of such, even in the absence of cognitive decline.

痴呆症是一种以认知改变为特征的综合症,会影响日常功能。神经精神症状(NPS)也很普遍,甚至可能在认知能力明显下降之前就已出现。尽管有越来越多的研究证据表明,神经精神症状在几种痴呆综合症中出现得较早且频繁,甚至在认知能力没有下降的情况下也会出现(即轻度行为障碍 [MBI]),但神经精神症状与病程早期阶段的关联仍然较少。基层医疗团队是痴呆症护理的前沿阵地,但他们经常报告在痴呆症诊断和管理方面接受的培训不足。考虑到及时诊断痴呆症对于获得最佳疗效和最大干预效果至关重要,这就构成了一个严重的问题。我们简要回顾了四种痴呆综合征(阿尔茨海默病、血管性痴呆、路易体痴呆和行为变异性额颞叶痴呆)及其相关的神经精神表现,并提供了一目了然的临床指南,以帮助初级医疗团队成员识别可能的神经退行性疾病前兆,并提示进一步的检查。我们还为初级医疗团队成员回顾了痴呆症和 MBI 症状管理的下一步措施。正如这些痴呆综合征的 NPS 特征所证明的那样,即使没有认知功能衰退,老年人亚急性新发精神症状也应提示考虑正在出现的痴呆过程,并可能对其进行进一步检查。
{"title":"Neuropsychiatric presentations of common dementia syndromes: A concise review for primary care team members.","authors":"Zoë Bell, Maureen K O'Connor, Lauren R Moo","doi":"10.1111/jgs.19211","DOIUrl":"https://doi.org/10.1111/jgs.19211","url":null,"abstract":"<p><p>Dementia is a syndrome characterized by cognitive changes which interfere with daily functioning. Neuropsychiatric symptoms (NPS) are also pervasive and may even occur prior to any noticeable cognitive decline. Still, NPS are less associated with the early stages of the disease course, despite mounting research evidence that NPS present early and often in several dementia syndromes, even in the absence of cognitive decline (i.e., mild behavioral impairment [MBI]). Primary care teams are at the forefront of dementia care, yet they frequently report insufficient training in dementia diagnosis and management. This poses a serious problem considering that timely diagnosis of dementia is critical for optimal outcomes and maximum efficacy of intervention. We provide a concise narrative review of four dementia syndromes (Alzheimer's disease, vascular dementia, dementia with Lewy bodies, and behavioral variant frontotemporal dementia) and their associated neuropsychiatric presentations, as well as at-a-glance clinical guides, to help primary care team members recognize possible prodromal neurodegenerative disease and to prompt further workup. We also review next steps in the management of dementia and symptoms of MBI for primary care team members. As evidenced by the NPS profiles of these dementia syndromes, subacute new onset of psychiatric symptoms in an older adult should prompt consideration of an emerging dementia process and possible further workup of such, even in the absence of cognitive decline.</p>","PeriodicalId":94112,"journal":{"name":"Journal of the American Geriatrics Society","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142484435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Journal of the American Geriatrics Society
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