肿瘤研究与临床最新文献

{"title":"Efficacy comparison between gastrectomy combined with chemotherapy and chemotherapy alone for treatment of advanced gastric cancer with abdominal para-aortic lymph node metastasis","authors":"Xue Wang, Jiqing Wang, Song Liu","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.009","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.009","url":null,"abstract":"Objective \u0000To investigate the therapeutic effect and prognosis of gastrectomy combined with chemotherapy and chemotherapy alone for treatment of advanced gastric cancer with abdominal para-aortic (the 16th) lymph node metastasis. \u0000 \u0000 \u0000Methods \u0000The clinical data of 236 patients with advanced gastric cancer with abdominal para-aortic (the 16th) lymph node metastasis in Jincheng People's Hospital of Shanxi Province from January 2003 to December 2012 were retrospectively analyzed. According to the treatment method, the patients were divided into chemotherapy alone group (121 cases) and gastrectomy + chemotherapy group (115 cases), and mFOLFOX6 regimen was used for chemotherapy. The efficacy and adverse reactions of the two groups were compared. \u0000 \u0000 \u0000Results \u0000The incidence of upper gastrointestinal adverse events in the gastrectomy+chemotherapy group was higher than that in the chemotherapy alone group [8.7% (10/115) vs. 1.7% (2/121)], and the difference between the two groups was statistically significant (χ 2 = 3.881, P = 0.049). The median overall survival was 14.8 months (10.9-17.8 months) in the chemotherapy alone group and 11.7 months (9.8-15.6 months) in the gastrectomy+chemotherapy group, and there was no significant difference between the two groups (P > 0.05). The 2-year overall survival rate was 32.3% in the chemotherapy alone group and 24.3% in the gastrectomy+chemotherapy group, and there was no significant difference between the two groups (χ 2 = 3.105, P = 0.078). The 2-year progression-free survival rate was 16.5% in the chemotherapy alone group and 20.0% in the gastrectomy+chemotherapy group, and the difference between the two groups was statistically significant (χ 2 = 3.917, P = 0.047). \u0000 \u0000 \u0000Conclusion \u0000Compared with chemotherapy alone, advanced gastric cancer patients with abdominal para-aortic (the 16th) lymph node metastasis could not benefit from gastrectomy combined with chemotherapy. \u0000 \u0000 \u0000Key words: \u0000Stomach neoplasms; Drug therapy, combination; Gastrectomy","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"760-763"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44566158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical efficacy of surgical resection after conversion therapy for advanced gastric cancer","authors":"Kai Jia, Liwei Wang, Junjie Ma, Jinfeng Ma, Jun Xu","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.008","url":null,"abstract":"Objective \u0000To observe the clinical effect of surgical resection after conversion therapy for patients with advanced gastric cancer. \u0000 \u0000 \u0000Methods \u0000The clinical data of 23 patients with advanced gastric cancer who were admitted to Shanxi Provincial Cancer Hospital from January 2015 to October 2017 were retrospectively analyzed. All patients underwent multi-disciplinary treatment(MDT)-directed conversion therapy, and D2 radical gastrectomy was performed after the disappearance of non-healing factors. The remission of patients after conversion therapy and the related intraoperative and postoperative indicators were analyzed. \u0000 \u0000 \u0000Results \u0000After the conversion therapy, there were 2 cases (8.7%) of complete remission, 13 cases (56.5%) of partial remission and 8 cases (34.8%) of stable disease. The remission rate of the conversion therapy was 65.2% (15/23). In all 23 cases, the surgical time was (135.5±32.1) min, the intraoperative blood loss was (356.7±101.3) ml, the number of lymph nodes resected was 35.5±10.3. The time of gastric tube indwelling was (70.5±29.6) h, the time to first liquid intake was (85.0±21.5) h, the time of drainage tube placement was (196.2±36.2) h and the postoperative hospital stay was (10.7±3.2) d. After surgery, two cases had grade ⅢA post-operative complications and 2 had gradeⅡ. All patients were followed up, the median progression-free survival time was 13.5 months and the median overall survival time was 21.9 months. \u0000 \u0000 \u0000Conclusion \u0000The survival time of patients with advanced gastric cancer can be prolonged by D2 radical gastrectomy after the MDT-guided conversion therapy. \u0000 \u0000 \u0000Key words: \u0000Gastric neoplasms; Surgical procedures, operative; Conversion therapy; Multi-disciplinary team","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"756-759"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49139416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Progress of biological characteristics of stress granules and their relationship with tumors","authors":"Xianying Li, Dalong Yin, Lianxin Liu","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.016","url":null,"abstract":"Eukaryotes inhibit the translation of mRNA under stress conditions and form particles-stress granules (stress granules). At present, stress granules have been proved to be related to the occurrence and development of a variety of diseases, including tumors. The production of stress granules is promoted by microenvironment such as hypoxia and hyperactive oxygen in tumor cells, while stress granules-related proteins such as G3BP1, RACK1, YB-1 and mammalian target of rapamycin (mTOR) can promote the occurrence and metastasis of tumors, but the mechanism is not yet clear. In addition, studies have linked the formation of stress granules to the survival of tumor cells during chemotherapy, and believe that stress granules play a role in the treatment of tumors by different anti-tumor drugs. This review introduces the biological characteristics of stress granules and their relationship with tumors. \u0000 \u0000 \u0000Key words: \u0000Neoplasms; Stress granules; Antineoplastic drugs","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"778-782"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42627554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation of the human papillomavirus infection status and genotyping with the result of liquid-based thin-layer cytology of cervix in the female physical examiners in Xi'an","authors":"Hongyun Chang, Xiaofeng Li, Yuanyuan Wang, P. Nan, Xiao-meng Zhao","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.001","url":null,"abstract":"Objective \u0000To investigate the correlation of human papillomavirus (HPV) infection status and genotyping characteristics with the result of liquid-based thin-layer cytology (TCT) of the cervix in the female physical examiners in Xi'an. \u0000 \u0000 \u0000Methods \u0000The data of 5 163 female physical examiners who underwent HPV and TCT screening simultaneously in the First Affiliated Hospital of Xi'an Jiaotong University From June 2017 to June 2018 were collected to analyze HPV infection, genotyping and their relationship with TCT. \u0000 \u0000 \u0000Results \u0000Among the 5 163 examiners, 527 (10.21%) were HPV-positive, and the infection rate in the examiners over 60 years old was the highest [12.26% (57/465)]. Among HPV-positive examiners, the infection rate of single genotype was higher than that of multiple genotypes infection [75.90% (400/527) vs. 24.10% (127/527), P 0.05]. Among 50 examiners with positive results of HPV and TCT tests, the top four genotypes were type 58, 52, 53 and 16, and they were in consistence with the overall HPV infection genotyping. \u0000 \u0000 \u0000Conclusions \u0000The HPV infection in the female physical examiners in Xi'an is dominated by the single genotype infection, and the main genotypes of HPV infection are type 52, 58, 53 and 16. The combined detection of HPV genotyping and TCT can improve the effectiveness of cervical lesions screening. \u0000 \u0000 \u0000Key words: \u0000Human papillomavirus; Genotype; Cervical intraepithelial neoplasia; Liquid-based cytology; Xi'an","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"721-724"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47232090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grade IV myelosuppression induced by gemcitabine combined with cisplatin: report of one case and review of literature","authors":"H. Zemin, Liu Keting, Yu Nanbin","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.011","url":null,"abstract":"目的 \u0000提高对吉西他滨致骨髓抑制的识别。 \u0000 \u0000 \u0000方法 \u0000回顾性分析自贡市第三人民医院收治的1例肺鳞状细胞癌患者在化疗时发生骨髓抑制的诊治过程，并复习相关文献。 \u0000 \u0000 \u0000结果 \u0000该患者以咳嗽伴咯血入院，行支气管镜病理诊断为右肺下叶肺鳞状细胞癌伴右侧胸膜转移，患者予多西他赛、奈达铂化疗后未见明显好转，改为吉西他滨、顺铂化疗，后出现Ⅳ级骨髓抑制，给予规范化治疗后骨髓抑制得到纠正。 \u0000 \u0000 \u0000结论 \u0000对于老年晚期癌症患者，应注意吉西他滨使用剂量；出现骨髓抑制后，在后续化疗方案中应注意调整剂量或推迟使用。","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"766-768"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41626711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of modified tracking components in CyberKnife treatment of thoracic and abdominal tumors","authors":"Guo-Quan Li, Yi Yu, Junping Cheng, Zhi-wen Liang, Xiao-le Zhu, S. Zhang, Zhen-jun Peng","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.002","url":null,"abstract":"Objective \u0000To improve synchrony tracking components of CyberKnife (tracking vest and tracking markers) and to analyze the clinical application value of the improved tracking components in CyberKnife treatment of thoracic and abdominal tumors. \u0000 \u0000 \u0000Methods \u0000The tracking apron was made of knitted four-side elastic spandex cloth and suture design of Velcro, which was used to stick the tracking markers on the chest and abdomen of patients. The tracking markers added a 2 cm thick light foam block to the bottom of the original markers, and then the hook face of the Velcro was fixed to the bottom of the light foam. The improved trace component (the improved component) and the original component (the vendor component) were applied to the lung tracking treatment model, and the manufacturer components were included in the reference group. Adoption of improved components into the observation group; 20 different types of respiratory waveforms were simulated and applied to the same mold plan. After treatment, the coverage rate, mean standard deviation, maximum standard deviation and the slope of XYZ-axis vs. R correlation graph were recorded. The relevant parameters of Synchrony model and wearable time of two components were compared, and the application significances of the improved tracking component in the breathing tracking process of the CyberKnife were evaluated. \u0000 \u0000 \u0000Results \u0000The maximum slope [median(interquartile range)] of XYZ-axis vs. R related graph in the reference group was 0.73 (3.89), 0.27 (0.49) and 0.34 (1.02), respectively. The maximum slope of XYZ-axis vs. R related graph in the observation group was 0.70 (2.78), 0.31 (0.30) and 0.36 (0.75), respectively. There was no statistically significant difference in the slope of XYZ-axis vs. R between the reference group and the observation group (all P > 0.05). There was no significant difference in the average standard error and maximum standard error between the reference group and the observation group [(1.7±0.4) mm vs. (1.7±0.5) mm, t=-0.382, P= 0.710; (2.0±0.6) mm vs. (1.7±0.5) mm, t=-0.877, P= 0.401], and the difference of the model coverage rate between the two groups was statistically significant [(48±18)% vs. (60±22)%, t= 2.762, P= 0.042]. The setup time of tracking components in the observation group was less than that in the reference group, and the difference was statistically significant [(44±24) s vs. (81±15) s, t=-4.310, P= 0.001]. \u0000 \u0000 \u0000Conclusions \u0000The improved tracking components are comparable to the manufacturer tracking components in the standard error of the Synchrony model. The improved components shorten the wear time and appropriately improve the coverage of the Synchrony model. \u0000 \u0000 \u0000Key words: \u0000Thoracic neoplasms; Abdominal neoplasms; CyberKnife; Stereotactic body radiation therapy; Standard error; Synchrony model","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"725-728"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48784801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of Erastin in ferroptosis","authors":"Yuechen Zhao, Lili Zhong, Yinlong Zhao","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.11.017","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.11.017","url":null,"abstract":"Ferroptosis is a newly discovered form of cell death in recent years. Its essence is the cell peroxidation death caused by the accumulation of intracellular lipid reactive oxygen species (L-ROS) in a iron-dependent manner. As a highly efficient ferroptosis inducer, Erastin mediates ferroptosis through multiple molecules, such as cystine-glutamate transport receptor, voltage-dependent anion channel and p53. More importantly, Erastin can enhance the sensitivity of cancer cells to chemotherapy and radiotherapy, so it can be used as a new type of anticancer drug. This article reviews the discovery of Erastin, the pathways of ferroptosis, the pathways of Erastin-induced ferroptosis, the anti-tumor characteristics of Erastin, and the latest domestic and international research results. \u0000 \u0000 \u0000Key words: \u0000Cell death; Antineoplastic combined chemotherapy protocols; Erastin; Ferroptosis","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"782-786"},"PeriodicalIF":0.0,"publicationDate":"2019-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45558770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bisphosphonate-related osteonecrosis of the jaw in malignant tumor patients with bone metastases: clinical analysis of six cases","authors":"Pengfei Xin, Z. Tian, G. Xue","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.10.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.10.006","url":null,"abstract":"Objective \u0000To analyze the clinical manifestation, imaging characteristics and prevention of medication-related osteonecrosis of the jaw (MRONJ) after intravenous bisphosphonate (BP) for cancer patients with bone metastases. \u0000 \u0000 \u0000Methods \u0000The clinical data and radiographic findings of 6 primary breast cancer patients with bone metastases diagnosed as MRONJ from January 2014 to April 2018 in Shanxi Dayi Hospital were retrospectively analyzed. \u0000 \u0000 \u0000Results \u0000All 6 patients were female, with the median age of 65.5 years old. All patients had no history of systemic application of hormone therapy, no history of diabetes, no history of radiation therapy, no history of metastasis of the jaw, and no history of infection. The average usage time of BP was 28 months. MRONJ occurred in 2 cases on maxilla and 4 cases on mandible. There were 2 patients with tooth extractions history in BP treatment. Clinical symptoms included maxillofacial pain, loosened teeth, fistula suppuration, and exposed sequestrum. Radiographic findings included osteolysis and bone sclerosis or the mixed manifestation of both, with or without periosteal reaction. In addition, nonhealing tooth sockets and sequestrum separation imaging were also included. \u0000 \u0000 \u0000Conclusions \u0000Tooth extraction is considered as an increased risk for MRONJ in patients with malignant bone metastases after BP therapy. MRONJ is more likely to appear in the mandible, but it can also appear in the maxilla. Early screening and initiation of appropriate dental care are necessary for the patients before using BP therapy. \u0000 \u0000 \u0000Key words: \u0000Neoplasm metastasis; Diphosphonates; Skeleton; Medication-related osteonecrosis of the jaw","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"670-674"},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41398774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angioimmunoblastic T-cell lymphoma with high expression of CD20: clinical characteristics and prognosis analysis of five cases","authors":"Shao-jing Yang, Xiqing Chen, Zhuo Chen","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.10.013","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.10.013","url":null,"abstract":"目的 \u0000探讨CD20阳性血管免疫母细胞性T细胞淋巴瘤（AITL）的临床病理学特征。 \u0000 \u0000 \u0000方法 \u0000对广东省佛山市第一人民医院诊治的1例及文献报道的4例CD20阳性AITL患者的临床病理学特征及预后进行分析。 \u0000 \u0000 \u0000结果 \u00005例AITL患者中，男性4例，女性1例，平均年龄61岁。3例初诊时CD20阴性，复发时才表达CD20。3例出现误诊，其中2例误诊为非特指型外周T细胞淋巴瘤，1例误诊为弥漫大B细胞淋巴瘤。3例接受利妥昔单抗治疗，2例有效，1例无法评估疗效。 \u0000 \u0000 \u0000结论 \u0000CD20阳性AITL患者的临床病理特征易与B细胞淋巴瘤混淆，病理形态学、免疫组织化学及TCR基因重排检测等可减少误诊。利妥昔单抗是否有益尚不明确，应积极寻找有效的治疗方案，提高治愈率，改善患者预后。","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"700-703"},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41552804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application value of artificial intelligence-assisted diagnosis model in ultrasound diagnosis of breast nodules","authors":"H. Ji, Qiang Zhu, Conggui Gan, Shuai Zhou, Yun Cheng, Mingchang Zhao","doi":"10.3760/CMA.J.ISSN.1006-9801.2019.10.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1006-9801.2019.10.001","url":null,"abstract":"Objective \u0000To explore the application value of the convolutional neural network (CNN)-based artificial intelligence-assisted diagnosis model in the ultrasound differentiation diagnosis of benign and malignant breast nodules. \u0000 \u0000 \u0000Methods \u0000A total of 7 334 ultrasound images from 1 351 patients with breast nodules including 807 benign cases and 544 malignant cases were retrieved by using the CNN-based artificial intelligence-assisted diagnosis model from Beijing Tongren Hospital of Capital Medical University ultrasound images database between December 2006 and July 2017. The study included training subset (6 162 images), verification subset (555 images), and test subset (617 images), which were performed in the artificial intelligence-assisted diagnosis model. The outcome results of test subset in diagnosis model were compared with the pathological results. The sensitivity, specificity and accuracy of the artificial intelligence-assisted diagnosis model were calculated. \u0000 \u0000 \u0000Results \u0000After the test of 617 images, the model diagnostic results could be automatically output with a rectangular frame indicating the nodule position, benign and malignant diagnosis, benign and malignant probability values. The diagnosis time was approximately 4 seconds for each nodule. The sensitivity, specificity and accuracy of the diagnostic model in differentiating benign and malignant breast nodules were 84.1%, 95.0% and 91.2% , respectively. \u0000 \u0000 \u0000Conclusion \u0000The CNN-based artificial intelligence-assisted diagnosis model has satisfactory results in the differentiation diagnosis of the benign breast nodules and the malignant ones, which indicating the promising application prospect. \u0000 \u0000 \u0000Key words: \u0000Breast neoplasms; Convolutional neural network; Artificial intelligence; Auxiliary diagnosis","PeriodicalId":9505,"journal":{"name":"Cancer Research and Clinic","volume":"31 1","pages":"649-652"},"PeriodicalIF":0.0,"publicationDate":"2019-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45020627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}