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Bedřich Smetana's hearing loss could be caused by chronic mercury intoxication. Bedřich Smetana的听力损失可能是由慢性汞中毒引起的。
Q4 Medicine Pub Date : 2024-01-01
Ctibor Povýšil, Martin Kaňa, Jan Kučera

Bedřich Smetana's illness associated with complete hearing loss has been linked to various diseases in a long-running discussion. Senile dementia, atherosclerosis, progressive paralysis in lues are mentioned, while the ototoxicity of mercury is neglected. Its high concentration in the composer's skeletal remains was demonstrated by the authors of this article immunohistochemically and especially by the neutron activation analysis (NAA) method 23 years ago. The significance of this find has been neglected in connection with the dominant effort to prove the composer's venereal disease, the diagnosis of which, however, has not yet been unequivocally verified. Therefore, the existing results of the osteological examination were revised and the available sample was supplemented with an immunohistochemical examination using an antibody against treponemes and a silvering method with a negative result. On the other hand, an expert literature search focused on mercury ototoxicity confirmed our assumption that chronic intoxication with this metal, which was probably part of ointments applied not only in childhood but also later in adulthood, could contribute to hearing loss. This metal, until recently used in dermatology as a component of ointments, is resorbed and, as has recently been proven, causes various neuropsychic disorders, including disorders and even hearing loss. With this communication, we would like to initiate a new discussion on all aspects of the composer's illness.

Bedřich Smetana的疾病与完全听力丧失有关,在长期的讨论中与各种疾病联系在一起。老年性痴呆、动脉粥样硬化、进行性麻痹被提及,而汞的耳毒性被忽视。23年前,本文作者通过免疫组织化学特别是中子活化分析(NAA)方法证实了其在作曲家骨骼遗骸中的高浓度。这一发现的重要性被忽视了,因为人们一直在努力证明作曲家患有性病,然而,这种疾病的诊断还没有得到明确的证实。因此,对现有的骨学检查结果进行了修订,并对可用样本进行了免疫组织化学检查,使用抗梅毒抗体和银法进行了阴性结果。另一方面,一项专注于汞耳毒性的专家文献检索证实了我们的假设,即这种金属的慢性中毒可能会导致听力丧失,这种金属可能是儿童和成年后使用的软膏的一部分。这种金属,直到最近才被用作皮肤病学软膏的成分,被吸收,并且,正如最近被证明的那样,导致各种神经精神障碍,包括障碍甚至听力丧失。通过这次交流,我们想就作曲家病情的各个方面展开新的讨论。
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引用次数: 0
Modern approaches in multidisciplinary treatment of cleft lip and palate. 唇腭裂多学科治疗的现代方法。
Q4 Medicine Pub Date : 2024-01-01
Olga Košková, Michaela Richtrová, Petr Marcián, Libor Borák, Libor Streit, Tereza Bönischová, Radim Šabata, Alena Bryšová, Petr Štourač

Cleft lip and cleft palate are among the most common congenital defects of the head. The treatment of clefts is centralized, multidisciplinary, and involves a plastic surgeon, orthodontist, anesthesiologist, clinical speech therapist, and other specialists. While the incidence of cleft lip and cleft palate remains approximately unchanged, the approach to their treatment is evolving. Modern treatment methods increasingly include 3D printing and the associated therapeutic and educational possibilities.

唇裂和腭裂是最常见的先天性头部缺陷。唇裂的治疗是集中的、多学科的,包括整形外科医生、正畸医生、麻醉师、临床语言治疗师和其他专家。虽然唇裂和腭裂的发病率大致保持不变,但其治疗方法正在发展。现代治疗方法越来越多地包括3D打印和相关的治疗和教育的可能性。
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引用次数: 0
Bert Sakmann (1942-).
Q4 Medicine Pub Date : 2024-01-01
Pavel Čech
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引用次数: 0
Palliative versus intensive care from the perspective of the medical rescue service. 从医疗救援服务的角度看姑息治疗与重症监护。
Q4 Medicine Pub Date : 2024-01-01
Jiří Knor, Ladislav Kabelka, Jaroslav Pekara, Marek Slabý, Ladislav Dušek

According to surveys conducted over the last 10 years, more than 80 % of our population want to live with their loved ones at the end of life. With the ageing of the population and the success of medicine in the early stages of terminal illness, the trajectory and needs at the end of life are gradually changing. The need for health care support is increasing, and for most patients this means the need for 24/7 availability of health care, in this context in the home environment of the terminally ill patient. The question of how palliative care should be organised in an appropriate, meaningful and effective way, the role of specialised health care teams (mobile specialised palliative care), the role of general practitioners, and if, when and how the medical rescue service should/could/should effectively intervene in care, is becoming increasingly urgent. The article combines the experiences and views of an emergency physician and a doctor specialising in geriatrics and palliative medicine.

根据过去 10 年进行的调查,我国 80% 以上的人希望在生命终结时与亲人生活在一起。随着人口老龄化和医学在绝症早期阶段的成功,生命末期的轨迹和需求正在逐渐发生变化。对医疗保健支持的需求日益增加,对大多数病人来说,这意味着需要全天候的医疗保健服务,在这种情况下,需要在临终病人的家庭环境中提供医疗保健服务。如何以适当、有意义和有效的方式组织姑息关怀,专业医疗团队(移动式专业姑息关怀)的作用,全科医生的作用,以及医疗救援服务是否应该/能够/应该在何时以及如何有效地介入关怀,这些问题正变得日益紧迫。文章结合了一名急诊医生和一名老年病学与姑息治疗专科医生的经验和观点。
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引用次数: 0
Ethical dimensions in telemedicine - balancing technology, responsible care, and patient protection. 远程医疗中的伦理问题--平衡技术、负责任的护理和患者保护。
Q4 Medicine Pub Date : 2024-01-01
Anetta Jedličková

Telemedicine, defined as the practice of delivering healthcare services remotely using information and communications technologies, raises a plethora of ethical considerations. As telemedicine evolves, its ethical dimensions play an increasingly pivotal role in balancing the benefits of advanced technologies, ensuring responsible healthcare practices within telemedicine environments, and safeguarding patient rights. Healthcare providers, patients, policymakers, and technology developers involved in telemedicine encounter numerous ethical challenges that need to be addressed. Key ethical topics include prioritizing the protection of patient rights and privacy, which entails ensuring equitable access to remote healthcare services and maintaining the doctor-patient relationship in virtual settings. Additional areas of focus encompass data security concerns and the quality of healthcare delivery, underscoring the importance of upholding ethical standards in the digital realm. A critical examination of these ethical dimensions highlights the necessity of establishing binding ethical guidelines and legal regulations. These measures could assist stakeholders in formulating effective strategies and methodologies to navigate the complex telemedicine landscape, ensuring adherence to the highest ethical standards and promoting patient welfare. A balanced approach to telemedicine ethics should integrate the benefits of telemedicine with proactive measures to address emerging ethical challenges and should be grounded in a well-prepared and respected ethical framework.

远程医疗被定义为利用信息和通信技术远程提供医疗保健服务的做法,它提出了大量伦理方面的考虑。随着远程医疗的发展,其伦理层面在平衡先进技术的益处、确保远程医疗环境中负责任的医疗实践以及保障患者权利方面发挥着越来越关键的作用。参与远程医疗的医疗服务提供者、患者、政策制定者和技术开发者遇到了许多需要解决的伦理挑战。关键的伦理问题包括优先保护患者的权利和隐私,这就需要确保公平获得远程医疗服务,并在虚拟环境中保持医患关系。其他重点领域包括数据安全问题和医疗保健服务的质量,强调了在数字领域坚持伦理标准的重要性。对这些伦理层面的批判性研究凸显了制定具有约束力的伦理准则和法律法规的必要性。这些措施可以帮助利益相关方制定有效的战略和方法,驾驭复杂的远程医疗环境,确保遵守最高的道德标准,促进患者福利。一种平衡的远程医疗伦理方法应将远程医疗的益处与应对新出现的伦理挑战的积极措施相结合,并应以准备充分、受人尊重的伦理框架为基础。
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引用次数: 0
Trends in the representation of specialties caring for patients with diabetes in the Czech Republic. 捷克共和国糖尿病患者专科分布趋势。
Q4 Medicine Pub Date : 2024-01-01
Milan Kvapil, Martina Nováková, Klára Benešová, Jiří Jarkovský, Ladislav Dušek

The increasing prevalence of diabetes mellitus (DM) leads to the differentiation of the registration of diabetics in individual specialties. Objective of this paper was the evaluation of changes in the representation of expertise providing care for patients with DM (pDM) in the Czech Republic, based on data analysis from the National Register of Paid Health Services (NRHZS) 2010-2021. In the entire pDM group, the number of patients treated by a diabetologist (DIA) increased from 491,490 (57.0 %) to 537,430 (50.4 %), with a general practitioner (GP) from 27,719 (3.2 %) to 181,330 (17.0 %) and by internist (INT) from 172,918 (20.0 %) to 161,291 (15.1 %). In 2021, 57.9 % DIA, 17 % GP, 12.2 % INT were treated from the group treated with antidiabetics (813,873). In 2021, 84,345 were treated with insulin alone (87.2 % DIA), 129,127 were treated with a combination of insulin and non-insulin antidiabetics; 115,604 (91.6 %) in DIA, 322 (0.3 %) in GP and 7,983 (6.3 %) in INT. 603,331 treated only with non-insulin antidiabetic drugs, of which 281,929 (46.7 %) DIA, 137,744 (22.8 %) GP and 85,273 (14.1 %) INT. For other specialties, 98,385 (16.3 %) persons. 185,838 patients without reported DIA/GP/INT control, of which 80,144 without therapy. The increasing prevalence of DM and changes in reimbursement conditions are reflected in the dynamic development of the distribution of diabetes care by individual specialties.

糖尿病(DM)发病率的不断上升导致了糖尿病患者在各个专科登记情况的不同。本文的目的是根据2010-2021年国家付费医疗服务登记册(NRHZS)的数据分析,评估捷克共和国为糖尿病患者(pDM)提供医疗服务的专业代表性的变化。在整个糖尿病患者群体中,接受糖尿病专家(DIA)治疗的患者人数从 491 490 人(57.0%)增加到 537 430 人(50.4%),接受全科医生(GP)治疗的患者人数从 27 719 人(3.2%)增加到 181 330 人(17.0%),接受内科医生(INT)治疗的患者人数从 172 918 人(20.0%)增加到 161 291 人(15.1%)。2021 年,在接受抗糖尿病药物治疗的人群(813 873 人)中,57.9%接受了内科医生治疗,17%接受了全科医生治疗,12.2%接受了内科医生治疗。2021 年,84 345 人只接受胰岛素治疗(87.2% DIA),129 127 人接受胰岛素和非胰岛素抗糖尿病药物联合治疗;其中 115 604 人(91.6%)接受 DIA 治疗,322 人(0.3%)接受 GP 治疗,7 983 人(6.3%)接受 INT 治疗。603 331 人只接受了非胰岛素抗糖尿病药物治疗,其中 281 929 人(46.7%)接受了 DIA 治疗,137 744 人(22.8%)接受了 GP 治疗,85 273 人(14.1%)接受了 INT 治疗。其他专科患者为 98,385 人(16.3%)。185,838名患者未报告DIA/GP/INT控制情况,其中80,144人未接受治疗。糖尿病发病率的增加和报销条件的变化反映在各专科糖尿病治疗分布的动态发展上。
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引用次数: 0
30 let Společnosti pro léčbu závislosti na tabáku (SLZT). 烟草依赖治疗学会(STD)成立 30 周年。
Q4 Medicine Pub Date : 2024-01-01
Eva Králíková, Alexandra Pánková, Lenka Štěpánková, Kamila Zvolská, Kateřina Křenková

History and main activities of the Society for the Treatment of Tobacco Dependence (SLZT) over its 30 years of activity are aimed at pre/postgraduate education of physicians, nurses and pharmacists, it has been involved in the publication of first smoking cessation recommendations, then in 2005, 2015 and 2022 guidelines for treatment of tobacco dependence, has supported payment codes for medical interventions for tobacco dependence treatment and at least minimal contributions from health insurance companies for tobacco dependence medications, and was at the birth of the smoking cessation helpline. SLZT has published and disseminated dozens of patient leaflets focusing on different clinical areas of the impact of smoking, lobbied for better tobacco control legislation, and is involved in the international smoke-free hospitals project (GNTH - The Global Network for Tobacco Free Healthcare Services). It annually awards the SLZT Prize for the dissemination of tobacco dependence treatment in the field. It collaborates with other clinically oriented professional societies as well as the Working Group on Prevention and Treatment of Tobacco Dependence of the Czech Medical Association of J. E. Purkyně.

烟草依赖治疗协会(SLZT)30 年来的历史和主要活动旨在对医生、护士和药剂师进行毕业前/毕业后教育,参与发布了第一份戒烟建议,随后又于 2005 年、2015 年和 2022 年发布了烟草依赖治疗指南,支持为烟草依赖治疗的医疗干预制定支付规范,支持医疗保险公司至少为烟草依赖药物提供最低限度的缴费,并参与了戒烟帮助热线的诞生。SLZT 出版发行了数十种针对不同临床领域吸烟影响的患者宣传单,游说制定更好的烟草控制立法,并参与了国际无烟医院项目(GNTH - 无烟医疗服务全球网络)。它每年都会为烟草依赖治疗领域的传播颁发 SLZT 奖。它与其他临床专业协会以及 J. E. Purkyně 捷克医学协会的烟草依赖预防和治疗工作组开展合作。
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引用次数: 0
The topic of not initiating resuscitation from the perspective of Czech law not only in the context of palliative care. 从捷克法律的角度来看,不启动复苏的话题不仅适用于姑息治疗。
Q4 Medicine Pub Date : 2024-01-01
David Bláha, Pavel Böhm

In the age of advanced modern medicine, prolonging the lives of patients is becoming easier and easier. Science is even going so far that some authors are beginning to see the need to advocate for the patient's right to die. The authors of the recommended resuscitation procedures themselves state that prolonging the inevitable dying process should be considered a harm (dysthanasia). The issue of not initiating urgent resuscitation is part of not only clinical practice, but also the study of physicians and other health professionals. The various criteria, indications, and contraindications for this action are repeatedly discussed in the course of study and practice, but rarely does this discussion go into significant detail. The teaching is limited to their enumeration or description of some of the more clearly understood ones, which are, for example, certain signs of death and their presence. The terminal stage of an incurable chronic disease is only marginally mentioned as a contraindication to urgent resuscitation, perhaps due to its ethical and legal overlap. The article includes an analysis of the sources of regulation of this issue, focusing mainly on legal and professional sources and their relationship. It also describes the actual process of decision making about the initiation of palliative care, decision making about end-of-life care, including the issue of not initiating urgent resuscitation.

在现代医学发达的时代,延长病人的生命变得越来越容易。科学甚至发展到一些作者开始认为有必要倡导病人的死亡权利。推荐复苏程序的作者自己也表示,延长不可避免的死亡过程应被视为一种伤害(dysthanasia)。不启动紧急复苏的问题不仅是临床实践的一部分,也是医生和其他医疗专业人员研究的一部分。在学习和实践过程中,人们反复讨论这一行动的各种标准、适应症和禁忌症,但很少有详细的讨论。教学内容仅限于列举或描述一些比较明确的内容,例如,死亡的某些征兆及其存在。不治慢性病的晚期作为紧急复苏的禁忌症只是略有提及,这可能是由于其在伦理和法律上的重叠性。文章分析了这一问题的监管来源,主要侧重于法律和专业来源及其关系。文章还描述了关于启动姑息治疗的实际决策过程、关于临终关怀的决策过程,包括不启动紧急复苏的问题。
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引用次数: 0
Culturally sensitive health care - cultural specifics of Roma patients. 对文化敏感的医疗保健--罗姆病人的文化特点。
Q4 Medicine Pub Date : 2024-01-01
Helena Hnilicová

Globally increasing ethnic diversity of patients brings new challenges for physicians regarding the provision of medical care to patients with different ethnic backgrounds. The starting point is the postulate that it is above all a certain culture that shapes the environment in which the patient meets and communicates with medical professionals, and this is reflected in the relationship between doctors and patients and their mutual communication. The article describes the cultural specifics of Roma patients and defines the most important principles of providing culturally sensitive health care to this unique group, which differs from the major population in many respects. The described principles and recommendations can also be used within the framework of health care for migrants and refugees, whose representation among our patients is increasing.

在全球范围内,病人的种族多样性日益增加,这给医生为不同种族背景的病人提供医疗服务带来了新的挑战。本文的出发点是这样一种假设,即首先是某种文化塑造了病人与医务人员会面和交流的环境,这一点也反映在医生与病人之间的关系以及他们之间的相互交流中。文章描述了罗姆病人的文化特点,并确定了为这一独特群体提供文化敏感性医疗保健服务的最重要原则。所述原则和建议也可用于移民和难民的医疗保健框架,因为他们在我们的病人中所占的比例越来越大。
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引用次数: 0
Ortner's syndrome in interdisciplinary collaboration. 跨学科合作中的奥特纳综合症。
Q4 Medicine Pub Date : 2024-01-01
Ivan Kalivoda, Jakub Konečný

Ortner's syndrome, also known as cardiovocal syndrome, is a rare cause of hoarseness due to compression of the left recurrent laryngeal nerve caused by pathology of cardiovascular structures in the mediastinum. It was first described by Norbert Ortner in 1897, who associated the syndrome with mitral stenosis. It typically presents as paresis of the left recurrent laryngeal nerve, which is mechanically compressed in the area of the aortic arch. The case report describes an 81-year-old non-smoker who was examined for two months of hoarseness. Laryngoscopic examination revealed paralysis of the left vocal cord, and CT of the neck and mediastinum with contrast showed ectasia of the ascending aorta and aneurysm of the aortic arch. The patient was consulted by both a cardiothoracic surgeon and an interventional radiologist, but due to his age and the incidental nature of the finding, neither surgical nor endovascular treatment was recommended. The patient was discharged home, where he later passed away surrounded by his family. The prognosis of these patients depends on prompt diagnosis and treatment. Early intervention can improve or restore vocal function. Regular monitoring and interdisciplinary collaboration are also crucial factors for optimal patient care.

Ortner's综合征,也称为心声综合征,是一种罕见的声音嘶哑的原因,是由纵隔心血管结构病理引起的左喉返神经压迫。1897年,诺伯特·奥特纳(Norbert Ortner)首次描述了该综合征,并将其与二尖瓣狭窄联系起来。典型表现为左喉返神经轻瘫,该神经在主动脉弓区域受到机械压迫。该病例报告描述了一位81岁的非吸烟者,他被检查了两个月的声音嘶哑。喉镜检查显示左声带麻痹,颈部及纵隔CT造影显示升主动脉及主动脉弓动脉瘤扩张。该患者接受了心胸外科医生和介入放射科医生的咨询,但由于他的年龄和发现的偶发性质,不建议手术或血管内治疗。病人出院回家,后来在家人的陪伴下去世。这些患者的预后取决于及时的诊断和治疗。早期干预可以改善或恢复声带功能。定期监测和跨学科合作也是最佳患者护理的关键因素。
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引用次数: 0
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