Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.015
Baohua Li, Huanhuan Liu, Xu Wang
Objective To investigate the effect and complications of elastic intramedullary nail in the treatment of long bone fracture of limbs in children. Methods A total of 98 children with long bone fracture of extremities who were treated by surgery in Luoyang Orthopedic-Traumatological Hospital from March 2016 to May 2019 were selected and divided into control group and observation group according to random numble table, with 49 cases in each group. The control group was treated by plate internal fixation and the observation group was treated by elastic intramedullary nail internal fixation. The operation time, incision length, intraoperative bleeding volume and postoperative drainage volume were compared between the two groups. The curative effect, time of fracture healing, start time of weight-bearing, treatment time in hospital and other prognosis related indexes of the two groups, complications of the two groups were compared. Results The operation time, incision length, intraoperative bleeding volume and postoperative drainage volume in the observation group were better than those in the control group, (39.23±7.20)min vs.(56.54±8.39)min, (2.56±0.94)cm vs.(10.92±2.34)cm, (37.43±10.12)ml vs.(115.64±16.56)ml, (16.23±6.39)ml vs.(49.09±8.28)ml, the differences were statistically significant (P 0.05). Conclusions Elastic intramedullary nail in the treatment of long bone fracture in children can effectively reduce the surgical trauma, improve the intraoperative hemorrhage, shorten the time of fracture healing and treatment time in hospital, and it is helpful to speed up the process of postoperative rehabilitation of children and has high safety. Key words: Elastic intramedullary nail; Internal fixation; Long bone fracture of limbs; Children
{"title":"Effect and complications of elastic intramedullary nailing in the treatment of long bone fracture of limbs in children","authors":"Baohua Li, Huanhuan Liu, Xu Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.015","url":null,"abstract":"Objective \u0000To investigate the effect and complications of elastic intramedullary nail in the treatment of long bone fracture of limbs in children. \u0000 \u0000 \u0000Methods \u0000A total of 98 children with long bone fracture of extremities who were treated by surgery in Luoyang Orthopedic-Traumatological Hospital from March 2016 to May 2019 were selected and divided into control group and observation group according to random numble table, with 49 cases in each group. The control group was treated by plate internal fixation and the observation group was treated by elastic intramedullary nail internal fixation. The operation time, incision length, intraoperative bleeding volume and postoperative drainage volume were compared between the two groups. The curative effect, time of fracture healing, start time of weight-bearing, treatment time in hospital and other prognosis related indexes of the two groups, complications of the two groups were compared. \u0000 \u0000 \u0000Results \u0000The operation time, incision length, intraoperative bleeding volume and postoperative drainage volume in the observation group were better than those in the control group, (39.23±7.20)min vs.(56.54±8.39)min, (2.56±0.94)cm vs.(10.92±2.34)cm, (37.43±10.12)ml vs.(115.64±16.56)ml, (16.23±6.39)ml vs.(49.09±8.28)ml, the differences were statistically significant (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Elastic intramedullary nail in the treatment of long bone fracture in children can effectively reduce the surgical trauma, improve the intraoperative hemorrhage, shorten the time of fracture healing and treatment time in hospital, and it is helpful to speed up the process of postoperative rehabilitation of children and has high safety. \u0000 \u0000 \u0000Key words: \u0000Elastic intramedullary nail; Internal fixation; Long bone fracture of limbs; Children","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"26 1","pages":"48-51"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83599531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.024
Yanling Gao
Objective To compare the differences in peripherally inserted central catheter (PICC) complications in patients with heart failure in different age groups and to provide strategies for reducing complications of PICC. Methods A total of 136 patients with heart failure who underwent PICC in Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2017 to December 2018 were enrolled in the study. They were divided into elderly group (≥60 years old, n=79) and non-elderly group (<60 years old, n=57). The differences in the incidence of oozing, catheterization, phlebitis, catheter blockage, infection, and venous thrombosis after PICC were compared. Results The total incidence of complication in the elderly group(12.09%, 15/79) was higher than that in the non-elderly group (6.50%, 5/57), P<0.05. Conclusions The incidence of complications of PICC in elderly patient with heart failure is higher, which suggests that medical staff should strengthen the propaganda of various complications of PICC in elderly patients, adopt different nursing strategies, and effectively reduce the related complications after PICC. Key words: Peripherally inserted central catheter; Heart failure; Complication
{"title":"Complications of PICC in patients with heart failure in different age groups","authors":"Yanling Gao","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.024","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.024","url":null,"abstract":"Objective \u0000To compare the differences in peripherally inserted central catheter (PICC) complications in patients with heart failure in different age groups and to provide strategies for reducing complications of PICC. \u0000 \u0000 \u0000Methods \u0000A total of 136 patients with heart failure who underwent PICC in Zhengzhou Central Hospital Affiliated to Zhengzhou University from January 2017 to December 2018 were enrolled in the study. They were divided into elderly group (≥60 years old, n=79) and non-elderly group (<60 years old, n=57). The differences in the incidence of oozing, catheterization, phlebitis, catheter blockage, infection, and venous thrombosis after PICC were compared. \u0000 \u0000 \u0000Results \u0000The total incidence of complication in the elderly group(12.09%, 15/79) was higher than that in the non-elderly group (6.50%, 5/57), P<0.05. \u0000 \u0000 \u0000Conclusions \u0000The incidence of complications of PICC in elderly patient with heart failure is higher, which suggests that medical staff should strengthen the propaganda of various complications of PICC in elderly patients, adopt different nursing strategies, and effectively reduce the related complications after PICC. \u0000 \u0000 \u0000Key words: \u0000Peripherally inserted central catheter; Heart failure; Complication","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"44 1","pages":"79-81"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90049241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.019
Chunwang Yang, Linghong Wang
Objective To evaluate the effect of ST segment elevation in lead aVR of electrocardiogram in the assessment of coronary artery stenosis and cardiac function of patients with myocardial infarction. Methods The clinical data of 75 patients with myocardial infarction admitted to the Third People’s Hospital of Liaocheng from January 2018 to January 2019 were analyzed retrospectively, according to the ST segment elevation of aVR lead, the participants were divided into ST segment elevation group (n=26) and non ST segment elevation group (n=49), the location of coronary artery stenosis, cardiac function index and the occurrence of cardiovascular events were compared between the two groups. Results According to the examination, the proportion of coronary artery stenosis in the left main trunk and the proximal part of left anterior descending artery in ST segment elevation group was higher than that in non ST segment elevation group, and the proportion of the distal part of left anterior descending artery was lower than that in non ST segment elevation group (P<0.05); 6-minute walking distance of ST segment elevation group was shorter than that of non ST segment elevation group (P<0.05); left ventricular ejection fraction (LVEF) was lower than that of non ST elevation group (P<0.05); the values of left ventricular end systolic diameter (LVESD) and left ventricular end diastolic diameter (LVEDd) in ST segment elevation group were significantly higher than those in non ST segment elevation group (P<0.05); the total incidence of cardiovascular events in ST elevation group was higher than that in non ST elevation group (P<0.05). Conclusions ST segment elevation in lead aVR of ECG can effectively judge the location of coronary artery stenosis in patients with myocardial infarction, and provide effective reference for clinical diagnosis and treatment. Key words: Myocardial infarction; Electrocardiogram; ST segment elevation; aVR lead
{"title":"Value of ST segment elevation in lead aVR of electrocardiogram in the assessment of coronary artery stenosis and cardiac function of patients with myocardial infarction","authors":"Chunwang Yang, Linghong Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.019","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.019","url":null,"abstract":"Objective \u0000To evaluate the effect of ST segment elevation in lead aVR of electrocardiogram in the assessment of coronary artery stenosis and cardiac function of patients with myocardial infarction. \u0000 \u0000 \u0000Methods \u0000The clinical data of 75 patients with myocardial infarction admitted to the Third People’s Hospital of Liaocheng from January 2018 to January 2019 were analyzed retrospectively, according to the ST segment elevation of aVR lead, the participants were divided into ST segment elevation group (n=26) and non ST segment elevation group (n=49), the location of coronary artery stenosis, cardiac function index and the occurrence of cardiovascular events were compared between the two groups. \u0000 \u0000 \u0000Results \u0000According to the examination, the proportion of coronary artery stenosis in the left main trunk and the proximal part of left anterior descending artery in ST segment elevation group was higher than that in non ST segment elevation group, and the proportion of the distal part of left anterior descending artery was lower than that in non ST segment elevation group (P<0.05); 6-minute walking distance of ST segment elevation group was shorter than that of non ST segment elevation group (P<0.05); left ventricular ejection fraction (LVEF) was lower than that of non ST elevation group (P<0.05); the values of left ventricular end systolic diameter (LVESD) and left ventricular end diastolic diameter (LVEDd) in ST segment elevation group were significantly higher than those in non ST segment elevation group (P<0.05); the total incidence of cardiovascular events in ST elevation group was higher than that in non ST elevation group (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000ST segment elevation in lead aVR of ECG can effectively judge the location of coronary artery stenosis in patients with myocardial infarction, and provide effective reference for clinical diagnosis and treatment. \u0000 \u0000 \u0000Key words: \u0000Myocardial infarction; Electrocardiogram; ST segment elevation; aVR lead","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"6 1","pages":"61-64"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75653748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.003
Y. Miao, Xin-Jian Gao, Ya-Wen Zheng, Zhihong Zhao, Y. Liu
Objective To investigate the relationship between the gene mutation of epidermal growth factor receptor (EGFR) and the clinical characteristics of lung adenocarcinoma. Methods The clinical data of 194 patients with lung adenocarcinoma diagnosed by surgical resection (pulmonary resection, wedge resection, or lobectomy) in the First Affiliated Hospital of Zhengzhou University from January 2017 to January 2019 were collected. The relationship between EGFR gene mutation and clinicopathological characteristics including sex, age, smoking history, tumor markers, adenocarcinoma pathological classification, extent of differentiation in patients with lung adenocarcinoma were analyzed, further searched for factors that predicted the mutations of EGFR. Results In the 194 patients with lung adenocarcinoma, there were 120 cases (61.86%) with EGFR gene mutation, the mutation rate of female was higher than that of male (χ2=10.746, P=0.001), the mutation rate of EGFR gene in patients of age≥60 was higher than that in patients of age 0.05). Among the main pathological types of lung adenocarcinoma, the proportion of acinar type was the highest in EGFR mutation group(63.9%, 124/194), the others were solid type, papillary type, adherent type, mucinous adenocarcinoma, the differences between the main pathological types and EGFR gene mutation, the differentiation degree of each excised lesion were statistically significant (χ2=10.275, 17.131; P=0.001, 0.001). There were more exons 19 and exon 21 in EGFR mutants, further analysis showed that there was significant difference between different pathological sub-types and mutations of exon 19 and exon 21(χ2=18.613, P=0.001). Conclusions EGFR gene mutation is related to sex, age, smoking history, main pathological types and tumor differentiation degrees, but it is not related to tumor marker. Mutations of exon 19 and exon 21 are related to main pathological types. Key words: Lung adenocarcinoma; Epidermal growth factor; Receptor; Pathology
{"title":"Relationship between gene mutation of epidermal growth factor receptor and clinical characteristics of lung adenocarcinoma","authors":"Y. Miao, Xin-Jian Gao, Ya-Wen Zheng, Zhihong Zhao, Y. Liu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.003","url":null,"abstract":"Objective \u0000To investigate the relationship between the gene mutation of epidermal growth factor receptor (EGFR) and the clinical characteristics of lung adenocarcinoma. \u0000 \u0000 \u0000Methods \u0000The clinical data of 194 patients with lung adenocarcinoma diagnosed by surgical resection (pulmonary resection, wedge resection, or lobectomy) in the First Affiliated Hospital of Zhengzhou University from January 2017 to January 2019 were collected. The relationship between EGFR gene mutation and clinicopathological characteristics including sex, age, smoking history, tumor markers, adenocarcinoma pathological classification, extent of differentiation in patients with lung adenocarcinoma were analyzed, further searched for factors that predicted the mutations of EGFR. \u0000 \u0000 \u0000Results \u0000In the 194 patients with lung adenocarcinoma, there were 120 cases (61.86%) with EGFR gene mutation, the mutation rate of female was higher than that of male (χ2=10.746, P=0.001), the mutation rate of EGFR gene in patients of age≥60 was higher than that in patients of age 0.05). Among the main pathological types of lung adenocarcinoma, the proportion of acinar type was the highest in EGFR mutation group(63.9%, 124/194), the others were solid type, papillary type, adherent type, mucinous adenocarcinoma, the differences between the main pathological types and EGFR gene mutation, the differentiation degree of each excised lesion were statistically significant (χ2=10.275, 17.131; P=0.001, 0.001). There were more exons 19 and exon 21 in EGFR mutants, further analysis showed that there was significant difference between different pathological sub-types and mutations of exon 19 and exon 21(χ2=18.613, P=0.001). \u0000 \u0000 \u0000Conclusions \u0000EGFR gene mutation is related to sex, age, smoking history, main pathological types and tumor differentiation degrees, but it is not related to tumor marker. Mutations of exon 19 and exon 21 are related to main pathological types. \u0000 \u0000 \u0000Key words: \u0000Lung adenocarcinoma; Epidermal growth factor; Receptor; Pathology","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"40 1","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74927825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.012
R. Jia
Objective To investigate the value of human papillomavirus (HPV) test combined with colposcopy in the diagnosis of distribution of patients with cervical atypical squamous cells (ASCUS). Methods A total of 214 patients with ASCUS who had cervical cytology examinations from January 2015 to January 2019 in Datong Integrated Hospital of Traditional Chinese and Western Medicine were selected. All patients underwent cervical cytology, high risk human papilloma virus(HR-HPV), colposcope and biopsy pathology examination, and the results were analyzed. Results The results of histopathological examination in 214 patients with ASCUS were as follows: 135 cases of inflammation, 24 cases of condyloma, 17 cases of cervical intraepithelial neoplasia (CIN Ⅰ), 20 cases of CIN Ⅱ, 15 cases of CIN Ⅲ, 1 case of invasive cancer, 1 case of adenocarcinoma, 1 case with high degree of glandular epithelium abnormality and 0 case with low degree of glandular epithelium abnormality. Among the 214 patients with ASCUS, 173 cases were positive and 41 cases were negative by HR-HPV. The number of HR-HPV positive cases in patients with inflammation, genital warts, CINI, CINII, CINIII, invasive carcinoma, adenocarcinoma, and high glandular epithelial abnormalities were 120 cases, 10 cases, 14 cases, 9 cases, 10 cases, 0 case, 0 case, 1 case. The number of HR-HPV negative cases in patients with inflammation, genital warts, CIN I, CIN II, CIN III, invasive carcinoma, adenocarcinoma, and high glandular epithelial abnormalities were 15 cases, 4 cases, 3 cases, 11 cases, 5 cases, 1 case, 1 case, 0 case. Histopathological examination results showed that there were a total of 141 cases of high CIN, 3 points and above in patients with inflammation, genital warts and CINI. There were 27 cases of high CIN in CIN II and CIN III.There were 2 cases of high CIN in invasive carcinoma, adenocarcinoma, high glandular epithelial abnormality, and low grade glandular epithelial abnormalities. The difference between the two was significant (Z=-24.621, P<0.05). Conclusions HPV combined with colposcopy can reduce ASCUS false positive, which is beneficial for clinical of hig-risk ASCUS patients. Key words: Human papillomavirus; Cervical cytology; Atypical squamous cells; Colposcopy
{"title":"Significance of HPV test combined with colposcopy in distribution of patients with cervical atypical squamous cells","authors":"R. Jia","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.012","url":null,"abstract":"Objective \u0000To investigate the value of human papillomavirus (HPV) test combined with colposcopy in the diagnosis of distribution of patients with cervical atypical squamous cells (ASCUS). \u0000 \u0000 \u0000Methods \u0000A total of 214 patients with ASCUS who had cervical cytology examinations from January 2015 to January 2019 in Datong Integrated Hospital of Traditional Chinese and Western Medicine were selected. All patients underwent cervical cytology, high risk human papilloma virus(HR-HPV), colposcope and biopsy pathology examination, and the results were analyzed. \u0000 \u0000 \u0000Results \u0000The results of histopathological examination in 214 patients with ASCUS were as follows: 135 cases of inflammation, 24 cases of condyloma, 17 cases of cervical intraepithelial neoplasia (CIN Ⅰ), 20 cases of CIN Ⅱ, 15 cases of CIN Ⅲ, 1 case of invasive cancer, 1 case of adenocarcinoma, 1 case with high degree of glandular epithelium abnormality and 0 case with low degree of glandular epithelium abnormality. Among the 214 patients with ASCUS, 173 cases were positive and 41 cases were negative by HR-HPV. The number of HR-HPV positive cases in patients with inflammation, genital warts, CINI, CINII, CINIII, invasive carcinoma, adenocarcinoma, and high glandular epithelial abnormalities were 120 cases, 10 cases, 14 cases, 9 cases, 10 cases, 0 case, 0 case, 1 case. The number of HR-HPV negative cases in patients with inflammation, genital warts, CIN I, CIN II, CIN III, invasive carcinoma, adenocarcinoma, and high glandular epithelial abnormalities were 15 cases, 4 cases, 3 cases, 11 cases, 5 cases, 1 case, 1 case, 0 case. Histopathological examination results showed that there were a total of 141 cases of high CIN, 3 points and above in patients with inflammation, genital warts and CINI. There were 27 cases of high CIN in CIN II and CIN III.There were 2 cases of high CIN in invasive carcinoma, adenocarcinoma, high glandular epithelial abnormality, and low grade glandular epithelial abnormalities. The difference between the two was significant (Z=-24.621, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000HPV combined with colposcopy can reduce ASCUS false positive, which is beneficial for clinical of hig-risk ASCUS patients. \u0000 \u0000 \u0000Key words: \u0000Human papillomavirus; Cervical cytology; Atypical squamous cells; Colposcopy","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"43 1","pages":"38-40"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86030931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.025
Hui-fen Liu, Dandan Yang, C. Hou
Objective To discuss the effect of butorphanol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section. Methods A total of 120 women who underwent cesarean delivery in Luoyang Maternal and Child Health Hospital from January 2017 to January 2019 were screened. The patients were divided into reference group and observation group by random number table method, 60 cases in each group. The reference group was given intravenous injection of buprenorphine in uterine body, the observation group was treated with butorphanol and dexamethasone on the basis of the control group. The incidences of adverse reactions in the two groups were compared. The sedation scores of the two groups of women were observed and compared before operation, 10 minutes after uterine body injection, and after completion of operation. The hemodynamic index levels of the two groups of women were recorded before operation, 40 minutes after uterine body injection, and after operation. Results Compared with reference group, the incidence of adverse reactions such as vomiting, nausea, chest tightness, facial flushing, hypertension, chills and tachycardia in the observation group showed a significant downward trend(P 0.05). Ten minutes after uterine body injection, the sedation score of control group showed a significant downward trend, while that of observation group showed a significant upward trend (P 0.05). Forty minutes after uterine body injection, the heart rate, mean arterial pressure and respiratory rate of the two groups were significantly increased, but the increasing range of observation group was lower than that of control group (P<0.05). Conclusions The clinical effect of budesonol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section is ideal, which can effectively alleviate various discomforts of maternal and reduce the incidence of various adverse reactions. Key words: Butorphanol; Dexamethasone; Cesarean section; Carprostol
{"title":"Effect of butorphanol combined with dexamethasone on prevention of adverse reactions of carprost in cesarean section","authors":"Hui-fen Liu, Dandan Yang, C. Hou","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.025","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.025","url":null,"abstract":"Objective \u0000To discuss the effect of butorphanol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section. \u0000 \u0000 \u0000Methods \u0000A total of 120 women who underwent cesarean delivery in Luoyang Maternal and Child Health Hospital from January 2017 to January 2019 were screened. The patients were divided into reference group and observation group by random number table method, 60 cases in each group. The reference group was given intravenous injection of buprenorphine in uterine body, the observation group was treated with butorphanol and dexamethasone on the basis of the control group. The incidences of adverse reactions in the two groups were compared. The sedation scores of the two groups of women were observed and compared before operation, 10 minutes after uterine body injection, and after completion of operation. The hemodynamic index levels of the two groups of women were recorded before operation, 40 minutes after uterine body injection, and after operation. \u0000 \u0000 \u0000Results \u0000Compared with reference group, the incidence of adverse reactions such as vomiting, nausea, chest tightness, facial flushing, hypertension, chills and tachycardia in the observation group showed a significant downward trend(P 0.05). Ten minutes after uterine body injection, the sedation score of control group showed a significant downward trend, while that of observation group showed a significant upward trend (P 0.05). Forty minutes after uterine body injection, the heart rate, mean arterial pressure and respiratory rate of the two groups were significantly increased, but the increasing range of observation group was lower than that of control group (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The clinical effect of budesonol combined with dexamethasone in preventing adverse reactions of carprost in cesarean section is ideal, which can effectively alleviate various discomforts of maternal and reduce the incidence of various adverse reactions. \u0000 \u0000 \u0000Key words: \u0000Butorphanol; Dexamethasone; Cesarean section; Carprostol","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"35 1","pages":"81-84"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82128432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective To understand the cervical human papillomavirus (HPV)infection of women in the family of esophageal cancer patients, and preliminarily explore the relationship between the cervical HPV infection and esophageal cancer. Methods The 300 female esophageal cancer patients or first-degree relatives of esophageal cancer patients in the high incidence area of esophageal cancer in Henan Province were selected, and they were examined for free cervical cancer screening. Another 300 healthy females who underwent cervical cancer screening in the First Affiliated Hospital of Zhengzhou University during the same period. A cross-sectional controlled study was performed to analyze the results of cervical cancer screening. Results The age of 300 female esophageal cancer patients or the first-degree relatives of esophageal cancer patients in the high incidence area of esophageal cancer in henan province was 24-73 years old and the median age was 47 years old, of which HPV infection rate was 18.0%(54/300), it was slightly higher than that in healthy women (14.0%, 42/300), but the difference was not significant (χ2=1.786, P=0.181). The thinprep cytologic test(TCT)results of female esophageal cancer patients or their first-degree female relatives showed that theproportion of patients with cervical lesions (2.0%, 6/300) compared with those of abnormal in health checkups (3.0%, 9/300), there was no significant difference (χ2=0.615, P=0.433). Conclusions The infection rate of cervical HPV in the family of esophageal cancer patients is slightly higher than that in the general population, so we should be paid attention to the primary prevention, providing certain basis for future research on the relationship between esophageal cancer and cervical cancer. Key words: Human papillomavirus; Esophageal cancer; Cervical cancer
{"title":"A cross-sectional survey of cervical human papillomavirus infection in family of esophageal cancer patients","authors":"Yun Zhong, Jiamin Sun, Li-Yi Liu, Wei Cui, Xiaoming Liu, Yidan Yuan, Li-ping Han","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.001","url":null,"abstract":"Objective \u0000To understand the cervical human papillomavirus (HPV)infection of women in the family of esophageal cancer patients, and preliminarily explore the relationship between the cervical HPV infection and esophageal cancer. \u0000 \u0000 \u0000Methods \u0000The 300 female esophageal cancer patients or first-degree relatives of esophageal cancer patients in the high incidence area of esophageal cancer in Henan Province were selected, and they were examined for free cervical cancer screening. Another 300 healthy females who underwent cervical cancer screening in the First Affiliated Hospital of Zhengzhou University during the same period. A cross-sectional controlled study was performed to analyze the results of cervical cancer screening. \u0000 \u0000 \u0000Results \u0000The age of 300 female esophageal cancer patients or the first-degree relatives of esophageal cancer patients in the high incidence area of esophageal cancer in henan province was 24-73 years old and the median age was 47 years old, of which HPV infection rate was 18.0%(54/300), it was slightly higher than that in healthy women (14.0%, 42/300), but the difference was not significant (χ2=1.786, P=0.181). The thinprep cytologic test(TCT)results of female esophageal cancer patients or their first-degree female relatives showed that theproportion of patients with cervical lesions (2.0%, 6/300) compared with those of abnormal in health checkups (3.0%, 9/300), there was no significant difference (χ2=0.615, P=0.433). \u0000 \u0000 \u0000Conclusions \u0000The infection rate of cervical HPV in the family of esophageal cancer patients is slightly higher than that in the general population, so we should be paid attention to the primary prevention, providing certain basis for future research on the relationship between esophageal cancer and cervical cancer. \u0000 \u0000 \u0000Key words: \u0000Human papillomavirus; Esophageal cancer; Cervical cancer","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"5 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81799478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.028
Jun-tao Shi, Shu-yuan Xu, Jun Wang
Objective To study the efficacy and safety of surgical resection of parotid benign tumor with small incision under earlobe. Methods A total of 84 cases of parotid benign tumor treated in the Second Affiliated Hospital of Henan University of Science and Technology from January 2015 to December 2018. The patients were divided into observation group and control group according to random number table method, with 42 cases in each group. The observation group was treated with small-incision tumor resection under earlobe, while the control group was treated with traditional operation. The operative indexes, complications were compared between the two groups. Results After operation, the observation group were superior to the control group in operation time, hospitalization time, incision length, intraoperative blood loss and total postoperative drainage, the differences were significant (P 0.05). Conclusions Compared to conventional surgery, parotid benign tumor resection has small incision under earlobe and less complication. Key words: Parotid gland; Small-incision resection under earlobe; Benign tumor; Complications
{"title":"Efficacy and safety of surgical resection of parotid benign tumor with small incision under earlobe","authors":"Jun-tao Shi, Shu-yuan Xu, Jun Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.028","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.028","url":null,"abstract":"Objective \u0000To study the efficacy and safety of surgical resection of parotid benign tumor with small incision under earlobe. \u0000 \u0000 \u0000Methods \u0000A total of 84 cases of parotid benign tumor treated in the Second Affiliated Hospital of Henan University of Science and Technology from January 2015 to December 2018. The patients were divided into observation group and control group according to random number table method, with 42 cases in each group. The observation group was treated with small-incision tumor resection under earlobe, while the control group was treated with traditional operation. The operative indexes, complications were compared between the two groups. \u0000 \u0000 \u0000Results \u0000After operation, the observation group were superior to the control group in operation time, hospitalization time, incision length, intraoperative blood loss and total postoperative drainage, the differences were significant (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Compared to conventional surgery, parotid benign tumor resection has small incision under earlobe and less complication. \u0000 \u0000 \u0000Key words: \u0000Parotid gland; Small-incision resection under earlobe; Benign tumor; Complications","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"14 1","pages":"91-93"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80382820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.029
X. Duan, Cong Ma, J. Hua
Objective To investigate the clinical efficacy of thalidomide combined with CHOP in the treatment of peripheral T-cell lymphoma. Methods A total of 72 patients with peripheral T-cell lymphoma treated in Liaocheng People’s Hospital from January 2017 to January 2019 were selected, and were divided into observation group (36 cases) and control group (36 cases) according to the random number table. CHOP was used in the control group, while thalidomide was used in the observation group. Three weeks was one course of treatment, and both groups received 8 consecutive courses of treatment. The clinical curative effect and levels of arginase 1 (Arg-1), vascular endothelial growth factor (VEGF), induce nitric oxide synthase (iNOS) compared before and after the two groups and the adverse reactions during the treatment of (gastrointestinal reaction, liver damage, bone marrow suppression, neurotoxicity, hair loss, skin rash) were compared between the two groups. Results After treatment, the total effective rate of observation group (86.11%) was higher than that of the control group (63.89%), the difference was statistically significant (P 0.05). Conclusions Thalidomide combined with CHOP has significant clinical effect in the treatment of peripheral T-cell lymphoma. It can effectively reduce Arg-1, VEGF and iNOS levels, without increasing the incidence of adverse reactions. Key words: Lymphoma, T-cell, peripheral; CHOP plan; Thalidomide
{"title":"Effect of thalidomide combined with CHOP on patients with peripheral T-cell lymphoma","authors":"X. Duan, Cong Ma, J. Hua","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.029","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.029","url":null,"abstract":"Objective \u0000To investigate the clinical efficacy of thalidomide combined with CHOP in the treatment of peripheral T-cell lymphoma. \u0000 \u0000 \u0000Methods \u0000A total of 72 patients with peripheral T-cell lymphoma treated in Liaocheng People’s Hospital from January 2017 to January 2019 were selected, and were divided into observation group (36 cases) and control group (36 cases) according to the random number table. CHOP was used in the control group, while thalidomide was used in the observation group. Three weeks was one course of treatment, and both groups received 8 consecutive courses of treatment. The clinical curative effect and levels of arginase 1 (Arg-1), vascular endothelial growth factor (VEGF), induce nitric oxide synthase (iNOS) compared before and after the two groups and the adverse reactions during the treatment of (gastrointestinal reaction, liver damage, bone marrow suppression, neurotoxicity, hair loss, skin rash) were compared between the two groups. \u0000 \u0000 \u0000Results \u0000After treatment, the total effective rate of observation group (86.11%) was higher than that of the control group (63.89%), the difference was statistically significant (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Thalidomide combined with CHOP has significant clinical effect in the treatment of peripheral T-cell lymphoma. It can effectively reduce Arg-1, VEGF and iNOS levels, without increasing the incidence of adverse reactions. \u0000 \u0000 \u0000Key words: \u0000Lymphoma, T-cell, peripheral; CHOP plan; Thalidomide","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"4 1","pages":"94-97"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89887003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-02-25DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.014
Yongqi Shi, Huaili Deng, Binhong Wang
Objective To investigate the relationship between intestinal flora and serum levels of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor α(TNF-α) in patients with untereated first-episode schizophrenia. Methods A total of 268 patients with untreated first-episode schizophrenia in Taiyuan Psychiatric Hospital from January 2016 to January 2018 were selected as the observation group, and 110 healthy people in the same period were selected as the control group. The levels of IL-6, IL-10 and TNF-α were detected by enzyme-linked immunosorbent assay (ELISA) in the two groups. The composition of Lactobacillus, Bifidobacterium, Bacteroides and Enterococcus were compared. The relationship between the composition of intestinal flora and the levels of IL-6, IL-10 and TNF-α was analyzed by Pearson correlation. Results The levels of IL-6, IL-10 and TNF-α in the observation group were higher than those in the control group (P<0.05); the number of Lactobacilli and Bifidobacteria in the intestinal flora of the observation group was lower than that of the control group (P<0.05). The numbers of Bacteroides and Enterococcus were higher than those of the control group (P<0.05). Lactobacillus/Bacteroides, Lactobacillus/Enterococcus, Bifidobacterium/Bacteroides and Bifidobacterium/Enterococcus in the observation group were lower than those in the control group (P<0.05). Lactobacilli/Bacteroides, Lactobacilli/Enterococcus, Bifidobacteria/Bacteroides, Bifidobacteria/Enterococcus were negatively correlated with the levels of IL-6, IL-10, TNF-α (r<0, P<0.05). Conclusions The levels of IL-6, IL-10 and TNF-α in serum of patients with first-episode schizophrenia were increased, and the imbalance of intestinal flora was closely related to the change of serum inflammatory factors, both of which played important roles in the development of schizophrenia. Key words: Schizophrenia; Untreated; Intestinal flora; Inflammatory factors
{"title":"Intestinal flora of patients untreated first-episode schizophrenia and its relationship with levels of IL-6, IL-10 and TNF-α in serum","authors":"Yongqi Shi, Huaili Deng, Binhong Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.014","url":null,"abstract":"Objective \u0000To investigate the relationship between intestinal flora and serum levels of interleukin-6 (IL-6), interleukin-10 (IL-10), tumor necrosis factor α(TNF-α) in patients with untereated first-episode schizophrenia. \u0000 \u0000 \u0000Methods \u0000A total of 268 patients with untreated first-episode schizophrenia in Taiyuan Psychiatric Hospital from January 2016 to January 2018 were selected as the observation group, and 110 healthy people in the same period were selected as the control group. The levels of IL-6, IL-10 and TNF-α were detected by enzyme-linked immunosorbent assay (ELISA) in the two groups. The composition of Lactobacillus, Bifidobacterium, Bacteroides and Enterococcus were compared. The relationship between the composition of intestinal flora and the levels of IL-6, IL-10 and TNF-α was analyzed by Pearson correlation. \u0000 \u0000 \u0000Results \u0000The levels of IL-6, IL-10 and TNF-α in the observation group were higher than those in the control group (P<0.05); the number of Lactobacilli and Bifidobacteria in the intestinal flora of the observation group was lower than that of the control group (P<0.05). The numbers of Bacteroides and Enterococcus were higher than those of the control group (P<0.05). Lactobacillus/Bacteroides, Lactobacillus/Enterococcus, Bifidobacterium/Bacteroides and Bifidobacterium/Enterococcus in the observation group were lower than those in the control group (P<0.05). Lactobacilli/Bacteroides, Lactobacilli/Enterococcus, Bifidobacteria/Bacteroides, Bifidobacteria/Enterococcus were negatively correlated with the levels of IL-6, IL-10, TNF-α (r<0, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The levels of IL-6, IL-10 and TNF-α in serum of patients with first-episode schizophrenia were increased, and the imbalance of intestinal flora was closely related to the change of serum inflammatory factors, both of which played important roles in the development of schizophrenia. \u0000 \u0000 \u0000Key words: \u0000Schizophrenia; Untreated; Intestinal flora; Inflammatory factors","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"346 1","pages":"44-47"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75467141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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