Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.006
Chaoyang Sun, Y. Hou, Deqi Yan, Shifeng Li, Zhong-jian Li
Objective To study the clinical efficacy and safety of transesophageal atrial pacing in the suppression and termination of paroxysmal supraventricular tachycardia (PSVT) in pregnancy. Methods Thirty-one pregnant women with PSVT treated in the Second Affiliated Hospital of Zhengzhou University from May 2004 to December 2018 were selected as research objects. All patients were stimulated by S1S1 for 2-5 times at a frequency of 30-50 times/minute faster than PSVT, and the initial voltage was 20 V. If the PSVT could not be stopped, the stimulation frequency, number of stimulation and output voltage could be increased properly for repeated S1S1 stimulation. If above methods could not work, RS2 stimulation should be used to terminate PSVT. Results PSVT in all patients were terminated by transesophageal atrial pacing. Of them, 28 cases were terminated after the stimulation of S1S1, and 3 cases were terminated after the stimulation of RS2, additionally. The clinical recovery rate was 100%. There was no adverse reaction in the treatment, and the heart rates of fetus were not affected. Conclusions Transesophageal atrial tachycardia is a safe, rapid and repeatable method for termination of PSVT in pregnancy. Key words: Pregnancy; Esophageal atrial pacing; Paroxysmal supraventricular tachycardia
{"title":"Transesophageal atrial pacing in the treatment of paroxysmal supraventricular tachycardia in pregnancy","authors":"Chaoyang Sun, Y. Hou, Deqi Yan, Shifeng Li, Zhong-jian Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.006","url":null,"abstract":"Objective \u0000To study the clinical efficacy and safety of transesophageal atrial pacing in the suppression and termination of paroxysmal supraventricular tachycardia (PSVT) in pregnancy. \u0000 \u0000 \u0000Methods \u0000Thirty-one pregnant women with PSVT treated in the Second Affiliated Hospital of Zhengzhou University from May 2004 to December 2018 were selected as research objects. All patients were stimulated by S1S1 for 2-5 times at a frequency of 30-50 times/minute faster than PSVT, and the initial voltage was 20 V. If the PSVT could not be stopped, the stimulation frequency, number of stimulation and output voltage could be increased properly for repeated S1S1 stimulation. If above methods could not work, RS2 stimulation should be used to terminate PSVT. \u0000 \u0000 \u0000Results \u0000PSVT in all patients were terminated by transesophageal atrial pacing. Of them, 28 cases were terminated after the stimulation of S1S1, and 3 cases were terminated after the stimulation of RS2, additionally. The clinical recovery rate was 100%. There was no adverse reaction in the treatment, and the heart rates of fetus were not affected. \u0000 \u0000 \u0000Conclusions \u0000Transesophageal atrial tachycardia is a safe, rapid and repeatable method for termination of PSVT in pregnancy. \u0000 \u0000 \u0000Key words: \u0000Pregnancy; Esophageal atrial pacing; Paroxysmal supraventricular tachycardia","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"24 1","pages":"19-21"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75513165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.008
Jilan Zhang, Lidan Wang
Objective To investigate the application value of high-frequency ultrasound in the diagnosis of diabetic lower extremity vascular diseases. Methods Fifty-two diabetic patients admitted to Yangquan Fourth People’s Hospital from March 2017 to May 2019 were selected as the observation group, and 52 healthy people who underwent physical examination during the same period were selected as the control group. All the participants underwent high-frequency ultrasound examination. And the lower extremity vascular lesion site, lower extremity vascular lesion type, vascular media thickness, vessel inner diameter and blood flow velocity of the two groups were compared. The characteristics of lower extremity artery sonogram were analyzed. Results The lower extremity vascular lesion rate in the observation group was 90.38%(47/52), higher than the 34.62%(18/52) in the control group, and the difference was statistically significant (P<0.05). There were significant differences between the observation group and control group in the incidences of plaque (50.00% vs. 19.23%), stenosis (51.92% vs. 28.85%) and occlusion (28.85% vs. 0), P< 0.05. In the observation group, the film thickness was higher than that in the control group, and the blood vessel diameter and blood flow velocity was lower than that in the control group, with statistically significant differences (P<0.05). Conclusions High-frequency ultrasound can be used in the early diagnosis of diabetic lower extremity vascular diseases. It can effectively identify the location, type and characteristics of lower extremity vascular diseases, and analyze vascular media thicknesses of different vessels, inner diameters and blood flow velocities, so as to provide a reliable reference to clinical diagnosis. Key words: Diabetes mellitus; Lower extremity vascular disease; High frequency ultrasound; Diagnostic value
目的探讨高频超声在糖尿病下肢血管疾病诊断中的应用价值。方法选取2017年3月至2019年5月阳泉市第四人民医院收治的糖尿病患者52例作为观察组，同期健康体检者52例作为对照组。所有的参与者都接受了高频超声检查。比较两组患者下肢血管病变部位、下肢血管病变类型、血管中膜厚度、血管内径及血流速度。分析了下肢动脉超声的特点。结果观察组下肢血管病变率为90.38%(47/52)，高于对照组的34.62%(18/52)，差异有统计学意义(P<0.05)。观察组与对照组斑块发生率(50.00% vs. 19.23%)、狭窄发生率(51.92% vs. 28.85%)、闭塞发生率(28.85% vs. 0)差异均有统计学意义(P< 0.05)。观察组膜厚高于对照组，血管直径、血流速度低于对照组，差异均有统计学意义(P<0.05)。结论高频超声可用于糖尿病下肢血管疾病的早期诊断。可有效识别下肢血管疾病的部位、类型和特征，分析不同血管的血管介质厚度、内径和血流速度，为临床诊断提供可靠参考。关键词:糖尿病;下肢血管疾病;高频超声;诊断价值
{"title":"Application value of high-frequency ultrasound in the diagnosis of diabetic lower extremity vascular diseases","authors":"Jilan Zhang, Lidan Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.008","url":null,"abstract":"Objective \u0000To investigate the application value of high-frequency ultrasound in the diagnosis of diabetic lower extremity vascular diseases. \u0000 \u0000 \u0000Methods \u0000Fifty-two diabetic patients admitted to Yangquan Fourth People’s Hospital from March 2017 to May 2019 were selected as the observation group, and 52 healthy people who underwent physical examination during the same period were selected as the control group. All the participants underwent high-frequency ultrasound examination. And the lower extremity vascular lesion site, lower extremity vascular lesion type, vascular media thickness, vessel inner diameter and blood flow velocity of the two groups were compared. The characteristics of lower extremity artery sonogram were analyzed. \u0000 \u0000 \u0000Results \u0000The lower extremity vascular lesion rate in the observation group was 90.38%(47/52), higher than the 34.62%(18/52) in the control group, and the difference was statistically significant (P<0.05). There were significant differences between the observation group and control group in the incidences of plaque (50.00% vs. 19.23%), stenosis (51.92% vs. 28.85%) and occlusion (28.85% vs. 0), P< 0.05. In the observation group, the film thickness was higher than that in the control group, and the blood vessel diameter and blood flow velocity was lower than that in the control group, with statistically significant differences (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000High-frequency ultrasound can be used in the early diagnosis of diabetic lower extremity vascular diseases. It can effectively identify the location, type and characteristics of lower extremity vascular diseases, and analyze vascular media thicknesses of different vessels, inner diameters and blood flow velocities, so as to provide a reliable reference to clinical diagnosis. \u0000 \u0000 \u0000Key words: \u0000Diabetes mellitus; Lower extremity vascular disease; High frequency ultrasound; Diagnostic value","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"25-28"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74234235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.028
A. Kang, S. Cheng
Objective To study the efficacy and safety of anilek in the treatment of postpartum hemorrhage due to uterine inertia. Methods A total of 70 patients with postpartum hemorrhage due to uterine inertia admitted to Linfen Maternal and Child Health Hospital from January 2016 to December 2018 were enrolled in the study. The patients were divided into misoprostol group and anilek group by the random number table method, with 35 cases in each group. The patients in misoprostol group were treated with misoprostol, the patients in anilek group were treated with intramuscular or intrauterine injection of anilek. The clinical effects of the two groups were evaluated, and the amount of bleeding and adverse reactions were recorded at 2 and 24 h after delivery. Results The total effective rate of hemostasis of the patients in the anilek group (94.29%, 33/35) was significantly higher than that in the misoprostol group (82.86%, 29/35), P 0.05). Conclusions Using anilek in the treatment of postpartum hemorrhage due to uterine inertia can achieve good clinical results and reduce the amount of postpartum hemorrhage, with high safety. Key words: Uterine inertia; Postpartum hemorrhage; Anilek; Misoprostol; Efficacy; Safety
{"title":"Efficacy and safety of anilek in the treatment of postpartum hemorrhage due to uterine inertia","authors":"A. Kang, S. Cheng","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.028","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.028","url":null,"abstract":"Objective \u0000To study the efficacy and safety of anilek in the treatment of postpartum hemorrhage due to uterine inertia. \u0000 \u0000 \u0000Methods \u0000A total of 70 patients with postpartum hemorrhage due to uterine inertia admitted to Linfen Maternal and Child Health Hospital from January 2016 to December 2018 were enrolled in the study. The patients were divided into misoprostol group and anilek group by the random number table method, with 35 cases in each group. The patients in misoprostol group were treated with misoprostol, the patients in anilek group were treated with intramuscular or intrauterine injection of anilek. The clinical effects of the two groups were evaluated, and the amount of bleeding and adverse reactions were recorded at 2 and 24 h after delivery. \u0000 \u0000 \u0000Results \u0000The total effective rate of hemostasis of the patients in the anilek group (94.29%, 33/35) was significantly higher than that in the misoprostol group (82.86%, 29/35), P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Using anilek in the treatment of postpartum hemorrhage due to uterine inertia can achieve good clinical results and reduce the amount of postpartum hemorrhage, with high safety. \u0000 \u0000 \u0000Key words: \u0000Uterine inertia; Postpartum hemorrhage; Anilek; Misoprostol; Efficacy; Safety","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"75 1","pages":"94-96"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78087420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.001
Qianhai Huang, Qianjin Liu, Huakun Zhang, Lu Ma, Zhaoyun Cheng
Objective To study the incidence and risk factors of perioperative stroke in patients with coronary heart disease complicated with carotid artery stenosis during coronary artery bypass grafting (CABG). Methods One hundred and twenty-four patients with coronary heart disease complicated with carotid artery stenosis admitted to Henan Provincial People’s Hospital from January 2017 to December 2017 were selected. All patients were treated by CABG but without carotid endarterectomy or carotid artery stent implantation at the same time. According to the results of preoperative color Doppler echocardiography, patients were divided into mild stenosis group (unilateral or bilateral internal carotid artery stenosis <50%, n=97) and moderate-severe stenosis group (unilateral or bilateral internal carotid artery stenosis ≥50%, n=27). The perioperative stroke incidences were compared between the two groups, and multivariate logistic regression was used to analyze the risk factors for stroke during perioperative period. Results There was no significant difference in the general data between the two groups (P>0.05). The incidence of perioperative stroke in the moderate-severe stenosis group (18.5%, 5/27) was higher than that in the mild stenosis group (3.01%, 3/97), P<0.05. Multivariate logistic regression analysis showed that moderate-severe stenosis of the carotid artery was an independent risk factor for perioperative stroke in patients with CABG (P<0.05). Conclusions Moderate to severe stenosis in unilateral or bilateral carotid arteries can increase the risk of stroke during perioperative period of CABG. The carotid artery revascularization should be performed in CABG, if indicated, to reduce the incidence of stroke. Key words: Coronary disease; Carotid artery stenosis; Coronary artery bypass grafting; Complications; Stroke
{"title":"Risk factors of perioperative stroke in patients with coronary heart disease complicated with carotid artery stenosis","authors":"Qianhai Huang, Qianjin Liu, Huakun Zhang, Lu Ma, Zhaoyun Cheng","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.001","url":null,"abstract":"Objective \u0000To study the incidence and risk factors of perioperative stroke in patients with coronary heart disease complicated with carotid artery stenosis during coronary artery bypass grafting (CABG). \u0000 \u0000 \u0000Methods \u0000One hundred and twenty-four patients with coronary heart disease complicated with carotid artery stenosis admitted to Henan Provincial People’s Hospital from January 2017 to December 2017 were selected. All patients were treated by CABG but without carotid endarterectomy or carotid artery stent implantation at the same time. According to the results of preoperative color Doppler echocardiography, patients were divided into mild stenosis group (unilateral or bilateral internal carotid artery stenosis <50%, n=97) and moderate-severe stenosis group (unilateral or bilateral internal carotid artery stenosis ≥50%, n=27). The perioperative stroke incidences were compared between the two groups, and multivariate logistic regression was used to analyze the risk factors for stroke during perioperative period. \u0000 \u0000 \u0000Results \u0000There was no significant difference in the general data between the two groups (P>0.05). The incidence of perioperative stroke in the moderate-severe stenosis group (18.5%, 5/27) was higher than that in the mild stenosis group (3.01%, 3/97), P<0.05. Multivariate logistic regression analysis showed that moderate-severe stenosis of the carotid artery was an independent risk factor for perioperative stroke in patients with CABG (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Moderate to severe stenosis in unilateral or bilateral carotid arteries can increase the risk of stroke during perioperative period of CABG. The carotid artery revascularization should be performed in CABG, if indicated, to reduce the incidence of stroke. \u0000 \u0000 \u0000Key words: \u0000Coronary disease; Carotid artery stenosis; Coronary artery bypass grafting; Complications; Stroke","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"51 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83091821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.014
You-min Li, Jie Mu, Yanliang Zhang
Objective To investigate the influencing factors of hip pain after hip replacement in the elderly patients. Methods A total of 106 elderly patients who underwent hip replacement in the Second Affiliated Hospital of Henan University of Science and Technology from March 2017 to October 2018 were selected. The incidence of pain within half a year after operation was recorded. The data of gender, age, body mass index, pathological type, operation mode, white blood cell (WBC), C-reactive protein (CRP), prosthesis type and activity time of hip joint were compared between pain group and non pain group. Logistic regression analysis were used to analyze the influencing factors of hip pain after hip replacement. Results The incidence of hip pain after hip replacement was 36.79% (39/106). Age, prosthesis type, postoperative hip joint activity time, postoperative CRP level and postoperative WBC level had statistic difference between pain group and non pain group (P 0.05). Age over 65 years, uncemented prosthesis, postoperative hip joint activity time >2 d, postoperative WBC>10×109/L, and postoperative CRP>10 mg/L were the influencing factors of hip pain after hip replacement. Conclusions Hip pain after hip replacement in the elderly can be affected by many factors, and the main influencing factors are age >65 years, uncemented prosthesis, postoperative hip joint activity time >2 d, postoperative WBC>10×109/L, and postoperative CRP >10 mg/L. Key words: Aged; Hip replacement; Hip pain; Influencing factors
{"title":"Influencing factors of hip pain after hip replacement in the elderly","authors":"You-min Li, Jie Mu, Yanliang Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.014","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.014","url":null,"abstract":"Objective \u0000To investigate the influencing factors of hip pain after hip replacement in the elderly patients. \u0000 \u0000 \u0000Methods \u0000A total of 106 elderly patients who underwent hip replacement in the Second Affiliated Hospital of Henan University of Science and Technology from March 2017 to October 2018 were selected. The incidence of pain within half a year after operation was recorded. The data of gender, age, body mass index, pathological type, operation mode, white blood cell (WBC), C-reactive protein (CRP), prosthesis type and activity time of hip joint were compared between pain group and non pain group. Logistic regression analysis were used to analyze the influencing factors of hip pain after hip replacement. \u0000 \u0000 \u0000Results \u0000The incidence of hip pain after hip replacement was 36.79% (39/106). Age, prosthesis type, postoperative hip joint activity time, postoperative CRP level and postoperative WBC level had statistic difference between pain group and non pain group (P 0.05). Age over 65 years, uncemented prosthesis, postoperative hip joint activity time >2 d, postoperative WBC>10×109/L, and postoperative CRP>10 mg/L were the influencing factors of hip pain after hip replacement. \u0000 \u0000 \u0000Conclusions \u0000Hip pain after hip replacement in the elderly can be affected by many factors, and the main influencing factors are age >65 years, uncemented prosthesis, postoperative hip joint activity time >2 d, postoperative WBC>10×109/L, and postoperative CRP >10 mg/L. \u0000 \u0000 \u0000Key words: \u0000Aged; Hip replacement; Hip pain; Influencing factors","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"114 1","pages":"47-49"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89119716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.022
Qiying Wang, Xiao-Lin Qian, J. Li
Objective To investigate the analgesic effects of ultrasound-guided bilateral erector spinae plane block (ESPB) on patients undergoing endoscopic transforaminal lumbar interbody fusion (TLIF). Methods Eighty-six patients who were going to have TLIF in the Third People’s Hospital of Henan Province from January 2018 to April 2019 were selected, and they were divided into control group and observation group according to random number table method, with 43 cases in each group. The control group received general anesthesia, while the observation group underwent ultrasound-guided bilateral ESPB on the basis of general anesthesia. On 1 hour, 6 hours, 12 hours, 24 hours and 48 hours after operation, visual analogue scale (VAS) scores during rest and overturning, times of self analgesia, times of remedial analgesia and satisfaction of analgesia of the two groups were observed. The incidence of adverse reactions of the two groups, such as drowsiness, nausea, urinary retention, wound infection, itchy skin, within 48 h after operation were recorded. Results At 1 hour, 6 hours, 12 hours, and 24 hours after surgery, the VAS scores during rest of the observation group were lower than those of the control group, allP 0.05). Conclusions Performing ultrasound-guided bilateral ESPB in endoscopic TLIF can provide good analgesic effects and alleviate postoperative pain. Key words: Analgesia; Ultrasound; Erector spinae plane block; Transforaminal lumbar interbody fusion; Adverse reactions; Satisfaction
{"title":"Analgesic effects of ultrasound-guided bilateral erector spinae plane block on patients undergoing endoscopic transforaminal lumbar interbody fusion","authors":"Qiying Wang, Xiao-Lin Qian, J. Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.022","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.022","url":null,"abstract":"Objective \u0000To investigate the analgesic effects of ultrasound-guided bilateral erector spinae plane block (ESPB) on patients undergoing endoscopic transforaminal lumbar interbody fusion (TLIF). \u0000 \u0000 \u0000Methods \u0000Eighty-six patients who were going to have TLIF in the Third People’s Hospital of Henan Province from January 2018 to April 2019 were selected, and they were divided into control group and observation group according to random number table method, with 43 cases in each group. The control group received general anesthesia, while the observation group underwent ultrasound-guided bilateral ESPB on the basis of general anesthesia. On 1 hour, 6 hours, 12 hours, 24 hours and 48 hours after operation, visual analogue scale (VAS) scores during rest and overturning, times of self analgesia, times of remedial analgesia and satisfaction of analgesia of the two groups were observed. The incidence of adverse reactions of the two groups, such as drowsiness, nausea, urinary retention, wound infection, itchy skin, within 48 h after operation were recorded. \u0000 \u0000 \u0000Results \u0000At 1 hour, 6 hours, 12 hours, and 24 hours after surgery, the VAS scores during rest of the observation group were lower than those of the control group, allP 0.05). \u0000 \u0000 \u0000Conclusions \u0000Performing ultrasound-guided bilateral ESPB in endoscopic TLIF can provide good analgesic effects and alleviate postoperative pain. \u0000 \u0000 \u0000Key words: \u0000Analgesia; Ultrasound; Erector spinae plane block; Transforaminal lumbar interbody fusion; Adverse reactions; Satisfaction","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"79 1","pages":"74-76"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72853370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.030
Qiao-yun Wang
Objective To observe the effects of mesalazine combined with Bifidobacterium tetravaccine capsules on ulcerative colitis (UC). Methods A total of 124 patients with UC treated in the Fifth People’s Hospital of Datong from May 2017 to April 2018 were selected as research objects, and they were divided into two groups by the random number table method, with 62 cases in each group. The control group was treated with mesalazine, and the observation group was treated with Bifidobacterium tetravaccine capsules and mesalazine. Clinical efficacy, inflammatory immune response and adverse reactions of the two groups were observed before and after treatment. Results After treatment, the total efficiency of the observation group was 93.55% (58/62), higher the 79.03% (49/62) of the control group, and the difference was statistically significant (P 0.05). After treatment, the levels of IgA, IgG and TNF-a in the observation group were (1.32±0.58)g/L, (8.16±0.54)g/L, (271.59±32.34)ng/L, respectively, lower than the (1.75±0.34)g/L, (10.59±0.47)g/L, (346.65±40.08)ng/L in the control group (P 0.05). Conclusions Methalazine combined with Bifidobacterium tetravaccine capsules in the treatment of UC patients is more helpful to suppress inflammatory response, improve immune function, and it is safe and effective. Key words: Ulcerative colitis; Mesalazine; Bifidobacterium tetravaccine capsules; Inflammatory immune response
{"title":"Effects of mesalazine combined with Bifidobacterium tetravaccine capsules on ulcerative colitis","authors":"Qiao-yun Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.030","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.030","url":null,"abstract":"Objective \u0000To observe the effects of mesalazine combined with Bifidobacterium tetravaccine capsules on ulcerative colitis (UC). \u0000 \u0000 \u0000Methods \u0000A total of 124 patients with UC treated in the Fifth People’s Hospital of Datong from May 2017 to April 2018 were selected as research objects, and they were divided into two groups by the random number table method, with 62 cases in each group. The control group was treated with mesalazine, and the observation group was treated with Bifidobacterium tetravaccine capsules and mesalazine. Clinical efficacy, inflammatory immune response and adverse reactions of the two groups were observed before and after treatment. \u0000 \u0000 \u0000Results \u0000After treatment, the total efficiency of the observation group was 93.55% (58/62), higher the 79.03% (49/62) of the control group, and the difference was statistically significant (P 0.05). After treatment, the levels of IgA, IgG and TNF-a in the observation group were (1.32±0.58)g/L, (8.16±0.54)g/L, (271.59±32.34)ng/L, respectively, lower than the (1.75±0.34)g/L, (10.59±0.47)g/L, (346.65±40.08)ng/L in the control group (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Methalazine combined with Bifidobacterium tetravaccine capsules in the treatment of UC patients is more helpful to suppress inflammatory response, improve immune function, and it is safe and effective. \u0000 \u0000 \u0000Key words: \u0000Ulcerative colitis; Mesalazine; Bifidobacterium tetravaccine capsules; Inflammatory immune response","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"3 1","pages":"100-102"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89637599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.003
R. Guo, Mengling Zhao, Yun Feng, Fen-Fen Chu, Miaomiao Zhang, Qian Wang
Objective To compare the curative effects on high-grade squamous intraepithelial lesion (HSIL) by performing total hysterectomy (LTH) immediately after fast frozen section examination (FSE) and performing total hysterectomy after fast FSE frozen section examination and conventional pathological determination. Methods Eighty-four patients with HSIL diagnosed in Pathology Department of the First Affiliated Hospital of Zhengzhou University from January 2016 to April 2017 who were going to have total hysterectomy operation were divided into two groups by their own willingness on operation. Patients in one-step operation group were given cervical cold knife conization (CKC) for FSE; if patients were diagnosed as non-cancer by FSE, patients underwent total hysterectomy immediately. Patients in two-step group underwent CKC for FSE first; if patients were diagnosed as non-cancer by FSE, clinicians ended the surgery; then, patients experienced routine pathological examination; if the results of pathological examination proved not to be cancer, patients underwent total hysterectomy; if the FSE showed a cancer result, patients underwent the radical operation of cervical cancer. The hospital stay, treatment coast, intraoperative bleeding volume, postoperative complication, anxiety degree and inappropriate rate of operation were compared between the two groups. Results Compared to two-step group, one-step group had shorter hospital stay, less hospital coast, lower anxiety degree and shorter time for the first anal exhaust (P 0.05). Conclusions Performing CKC and total hysterectomy at the same time has more advantages, however, it also has limited accuracy. Therefore, clinicians should attach importance to prevention of inappropriate hysterectomy, and investigation on high-risk of exacerbation of HSIL to guide the formulation of treatment protocol. Key words: Hysterectomy; High-grade intraepithelial lesion; Treatment; Fast frozen section examination; Conventional paraffin pathology
{"title":"Comparison of effects of hysterectomy at two different timings in patients with high-grade squamous intraepithelial lesion","authors":"R. Guo, Mengling Zhao, Yun Feng, Fen-Fen Chu, Miaomiao Zhang, Qian Wang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.003","url":null,"abstract":"Objective \u0000To compare the curative effects on high-grade squamous intraepithelial lesion (HSIL) by performing total hysterectomy (LTH) immediately after fast frozen section examination (FSE) and performing total hysterectomy after fast FSE frozen section examination and conventional pathological determination. \u0000 \u0000 \u0000Methods \u0000Eighty-four patients with HSIL diagnosed in Pathology Department of the First Affiliated Hospital of Zhengzhou University from January 2016 to April 2017 who were going to have total hysterectomy operation were divided into two groups by their own willingness on operation. Patients in one-step operation group were given cervical cold knife conization (CKC) for FSE; if patients were diagnosed as non-cancer by FSE, patients underwent total hysterectomy immediately. Patients in two-step group underwent CKC for FSE first; if patients were diagnosed as non-cancer by FSE, clinicians ended the surgery; then, patients experienced routine pathological examination; if the results of pathological examination proved not to be cancer, patients underwent total hysterectomy; if the FSE showed a cancer result, patients underwent the radical operation of cervical cancer. The hospital stay, treatment coast, intraoperative bleeding volume, postoperative complication, anxiety degree and inappropriate rate of operation were compared between the two groups. \u0000 \u0000 \u0000Results \u0000Compared to two-step group, one-step group had shorter hospital stay, less hospital coast, lower anxiety degree and shorter time for the first anal exhaust (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000Performing CKC and total hysterectomy at the same time has more advantages, however, it also has limited accuracy. Therefore, clinicians should attach importance to prevention of inappropriate hysterectomy, and investigation on high-risk of exacerbation of HSIL to guide the formulation of treatment protocol. \u0000 \u0000 \u0000Key words: \u0000Hysterectomy; High-grade intraepithelial lesion; Treatment; Fast frozen section examination; Conventional paraffin pathology","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"1 1","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77771084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.027
Yaqin Chen
Objective To investigate the efficacy of thioctic acid combined with mecobalamin in the treatment of peripheral neurotoxicity induced by radiochemotherapy in breast cancer patients. Methods A total of 94 breast cancer patients with peripheral neurotoxic adverse reactions induced by radiochemotherapy treated in the First Affiliated Hospital of Zhengzhou University from July 2017 to July 2018 were selected as research objects. And they were divided into control group and research group by random number table method. Patients in the research group (n=47) were treated with thioctic acid and mecobalamin, and patients in the control group (n=47) were treated with vitamin B12. The therapeutic effects of the two groups were analyzed and compared. Results The overall effective rate was 87.23% (41/47) in the research group, higher than the 51.06% (24/47) in the control group, and the difference was statistically significant (χ2=5.068, P<0.05). Conclusions Thioctic acid combined with mecobalamin has better therapeutic effects than vitamin B12 in the treatment of peripheral neurotoxicity caused by radiochemotherapy in breast cancer patients. Key words: Thioctic acid; Mecobalamin; Peripheral neurotoxicity
{"title":"Therapeutic effects of thioctic acid combined with mecobalamin on peripheral neurotoxicity induced by radiochemotherapy in patients with breast cancer","authors":"Yaqin Chen","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.027","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.027","url":null,"abstract":"Objective \u0000To investigate the efficacy of thioctic acid combined with mecobalamin in the treatment of peripheral neurotoxicity induced by radiochemotherapy in breast cancer patients. \u0000 \u0000 \u0000Methods \u0000A total of 94 breast cancer patients with peripheral neurotoxic adverse reactions induced by radiochemotherapy treated in the First Affiliated Hospital of Zhengzhou University from July 2017 to July 2018 were selected as research objects. And they were divided into control group and research group by random number table method. Patients in the research group (n=47) were treated with thioctic acid and mecobalamin, and patients in the control group (n=47) were treated with vitamin B12. The therapeutic effects of the two groups were analyzed and compared. \u0000 \u0000 \u0000Results \u0000The overall effective rate was 87.23% (41/47) in the research group, higher than the 51.06% (24/47) in the control group, and the difference was statistically significant (χ2=5.068, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Thioctic acid combined with mecobalamin has better therapeutic effects than vitamin B12 in the treatment of peripheral neurotoxicity caused by radiochemotherapy in breast cancer patients. \u0000 \u0000 \u0000Key words: \u0000Thioctic acid; Mecobalamin; Peripheral neurotoxicity","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"31 1","pages":"92-93"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81963535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-03-10DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.002
Jing Li, Hua Hong, D. Feng, Guozhu Wu, Ran Sun
Objective To investigate the predictive value of contrast-enhanced ultrasongraphy for rheumatoid arthritis synovitis activeness in clinical remission period. Methods Seventy-four patients (148 wrist joints) with remission rheumatoid arthritis diagnosed in Inner Mongolia People’s Hospital from September 2017 to July 2019 were selected. Of the enrolled patients, wrist joints with thickened synovial membrane were selected, and micro-vessels in synovial membrane were detected by power Doppler ultrasonography and contrast-enhanced ultrasonography. The examination results in synovial thickness, display rate of blood flow signals and blood flow classification of the two methods were compared. Results ①Mean synovial thickness detected by contrast-enhanced ultrasonography was (5.17±2.06)mm, which was better than the (4.89±2.00)mm detected by power Doppler ultrasonography (t=8.765, P<0.001). ② Display rate of blood flow signals determined by contrast-enhanced ultrasonography was 59.5% (69/116), better than the 26.7% (31/116) determined by power Doppler ultrasonography (P<0.001). ③ Contrast-enhanced ultrasonography was superior to power Doppler ultrasonography in classifying blood flow signals (Kappa=0.173, P=0.043). Conclusions Contrast-enhanced ultrasonography could more accurate reflect the rheumatoid arthritis synovitis activeness in clinical remission period, and guide the clinical treatment. Key words: Arthritis, rheumatoid; Clinical remission; Contrast-enhanced ultrasonography; Power Doppler ultrasound; Synovial inflammation
{"title":"Comparison of predictive values of power Doppler ultrasonography versus contrast-enhanced ultrasongraphy for rheumatoid arthritissynovitis activeness in clinical remission period","authors":"Jing Li, Hua Hong, D. Feng, Guozhu Wu, Ran Sun","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.002","url":null,"abstract":"Objective \u0000To investigate the predictive value of contrast-enhanced ultrasongraphy for rheumatoid arthritis synovitis activeness in clinical remission period. \u0000 \u0000 \u0000Methods \u0000Seventy-four patients (148 wrist joints) with remission rheumatoid arthritis diagnosed in Inner Mongolia People’s Hospital from September 2017 to July 2019 were selected. Of the enrolled patients, wrist joints with thickened synovial membrane were selected, and micro-vessels in synovial membrane were detected by power Doppler ultrasonography and contrast-enhanced ultrasonography. The examination results in synovial thickness, display rate of blood flow signals and blood flow classification of the two methods were compared. \u0000 \u0000 \u0000Results \u0000①Mean synovial thickness detected by contrast-enhanced ultrasonography was (5.17±2.06)mm, which was better than the (4.89±2.00)mm detected by power Doppler ultrasonography (t=8.765, P<0.001). ② Display rate of blood flow signals determined by contrast-enhanced ultrasonography was 59.5% (69/116), better than the 26.7% (31/116) determined by power Doppler ultrasonography (P<0.001). ③ Contrast-enhanced ultrasonography was superior to power Doppler ultrasonography in classifying blood flow signals (Kappa=0.173, P=0.043). \u0000 \u0000 \u0000Conclusions \u0000Contrast-enhanced ultrasonography could more accurate reflect the rheumatoid arthritis synovitis activeness in clinical remission period, and guide the clinical treatment. \u0000 \u0000 \u0000Key words: \u0000Arthritis, rheumatoid; Clinical remission; Contrast-enhanced ultrasonography; Power Doppler ultrasound; Synovial inflammation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"225 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76996368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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