首页 > 最新文献

Central Plains Medical Journal最新文献

英文 中文
Effects of endoscopic modified total laminoplasty on symptomatic lumbar spinal stenosis 内镜下改良全椎板成形术治疗症状性腰椎管狭窄的疗效
Pub Date : 2020-03-10 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.016
W. Du, Jue Wang, Yuan Lianjing, W. Qi, Luo Zhixiang
Objective To summarize the operation procedure and experience of endoscopic modified total laminoplasty (EMTL), and to investigate its short-term therapeutic effects on symptomatic lumbar spinal stenosis. Methods The clinical data of 22 patients with lumbar spinal stenosis who underwent EMTL in the First Affiliated Hospital of Zhengzhou University from August 2016 to August 2017 were retrospectively analyzed. The age, hospital stay, prior and posterior diameters in sagittal plane, bleeding volume, operation time, incision length, intraoperative and postoperative complications of the two groups were recorded. The effects of operation were evaluated by the visual analogue scale (VAS) of lumbago and lower extremity pain, Oswestry disability index (ODI) and Japan Orthopedic Association (JOA) score before and 1 year after operation. Results Among the 22 patients, 8 males and 14 females were included in the study, mean age (59.3 ± 9.6) years. All patients had neurogenic intermittent claudication with a distance of (339± 130)m. Eight patients showed spondylolisthesis or instability according to preoperative digital radiography (DR), computed tomography (CT) and magnetic resonance imaging (MRI). The VAS, ODI and JOA scores of lumbago and lower extremity pain 1 year after operation were significantly different from those before operation (P<0.05). The mean differences (95% confidence interval) of lumbago VAS, lower extremity VAS, ODI score and JOA score were 5.0 (4.3, 5.6), 4.1 (3.3, 4.8), 38.6 (35.7, 1.5), -14.2 (-16.2, -12.2), respectively, which were significantly improved, compared with those before operation. There was 1 case of dural injury during the operation, and 1 case of replantation without fusion determined by postoperative reexamination. And there was no other complications. Conclusions EMTL is effective in the treatment of symptomatic lumbar spinal stenosis. It can alleviate the symptoms of patients, improve their quality of life and satisfaction, with good safety. Key words: Laminoplasty; Total laminectomy; Minimally invasive; Endoscopy
目的总结内镜下改良全椎板成形术(EMTL)的手术方法和经验,探讨其治疗症状性腰椎管狭窄症的近期疗效。方法回顾性分析2016年8月至2017年8月郑州大学第一附属医院行EMTL治疗的22例腰椎管狭窄症患者的临床资料。记录两组患者的年龄、住院时间、前后矢状面直径、出血量、手术时间、切口长度、术中及术后并发症。采用术前、术后1年腰痛、下肢疼痛视觉模拟评分(VAS)、Oswestry残疾指数(ODI)、日本骨科协会(JOA)评分评价手术效果。结果22例患者中,男性8例,女性14例,平均年龄(59.3±9.6)岁。所有患者均有神经源性间歇性跛行,跛行距离为(339±130)m。根据术前数字x线摄影(DR),计算机断层扫描(CT)和磁共振成像(MRI), 8例患者表现为脊柱滑脱或不稳定。术后1年腰痛、下肢疼痛VAS、ODI、JOA评分与术前比较差异有统计学意义(P<0.05)。腰痛VAS、下肢VAS、ODI评分、JOA评分的平均差异(95%可信区间)分别为5.0(4.3,5.6)、4.1(3.3,4.8)、38.6(35.7,1.5)、-14.2(-16.2,-12.2),与术前比较均有显著改善。术中出现硬脑膜损伤1例,术后复查确定无融合再植1例。而且没有其他并发症。结论EMTL是治疗症状性腰椎管狭窄症的有效方法。可以缓解患者的症状,提高患者的生活质量和满意度,具有良好的安全性。关键词:椎板成形术;全椎板切除术;微创;内窥镜检查
{"title":"Effects of endoscopic modified total laminoplasty on symptomatic lumbar spinal stenosis","authors":"W. Du, Jue Wang, Yuan Lianjing, W. Qi, Luo Zhixiang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.016","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.016","url":null,"abstract":"Objective \u0000To summarize the operation procedure and experience of endoscopic modified total laminoplasty (EMTL), and to investigate its short-term therapeutic effects on symptomatic lumbar spinal stenosis. \u0000 \u0000 \u0000Methods \u0000The clinical data of 22 patients with lumbar spinal stenosis who underwent EMTL in the First Affiliated Hospital of Zhengzhou University from August 2016 to August 2017 were retrospectively analyzed. The age, hospital stay, prior and posterior diameters in sagittal plane, bleeding volume, operation time, incision length, intraoperative and postoperative complications of the two groups were recorded. The effects of operation were evaluated by the visual analogue scale (VAS) of lumbago and lower extremity pain, Oswestry disability index (ODI) and Japan Orthopedic Association (JOA) score before and 1 year after operation. \u0000 \u0000 \u0000Results \u0000Among the 22 patients, 8 males and 14 females were included in the study, mean age (59.3 ± 9.6) years. All patients had neurogenic intermittent claudication with a distance of (339± 130)m. Eight patients showed spondylolisthesis or instability according to preoperative digital radiography (DR), computed tomography (CT) and magnetic resonance imaging (MRI). The VAS, ODI and JOA scores of lumbago and lower extremity pain 1 year after operation were significantly different from those before operation (P<0.05). The mean differences (95% confidence interval) of lumbago VAS, lower extremity VAS, ODI score and JOA score were 5.0 (4.3, 5.6), 4.1 (3.3, 4.8), 38.6 (35.7, 1.5), -14.2 (-16.2, -12.2), respectively, which were significantly improved, compared with those before operation. There was 1 case of dural injury during the operation, and 1 case of replantation without fusion determined by postoperative reexamination. And there was no other complications. \u0000 \u0000 \u0000Conclusions \u0000EMTL is effective in the treatment of symptomatic lumbar spinal stenosis. It can alleviate the symptoms of patients, improve their quality of life and satisfaction, with good safety. \u0000 \u0000 \u0000Key words: \u0000Laminoplasty; Total laminectomy; Minimally invasive; Endoscopy","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"98 1","pages":"53-56"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76543342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Curative effects of emergency cervical cerclage on cervical incompetence and related factors influencing prognosis 急诊宫颈环切术治疗宫颈功能不全的疗效及影响预后的相关因素
Pub Date : 2020-03-10 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.011
Li Peng, Guiping Zhang, Xinyi Dan
Objective To investigate the curative effects of emergency cervical cerclage (ECC) on cervical incompetence (CIC), and to analyze the related factors influencing prognosis. Methods The clinical and pathological data from 36 CIC patients treated by ECC in Nanyang First People’s Hospital from June 2016 to June 2018 were retrospectively collected. The curative effects were analyzed. The pregnancy outcomes were compared among patients with different cervical dilatation degrees, and the related factors influencing prognosis were analyzed. Results After ECC, gestational weeks of 36 CIC patients were prolonged by (8.55±4.86)weeks, and the neonatal survival rate was 83.33%(30/36). Compared to cervical dilatation degree>6.0 cm group, cervical dilatation degree≤6.0 cm group had longer prolongation time of gestational week, less abortion cases and better neonatal weight, and the difference between the two groups was significant (P 2.5 cm group had longer prolongation time of gestational week, less abortion cases, better neonatal weight, and the difference between the two groups was significant (P 6.0 cm were independent risk factors influencing pregnancy outcomes (P<0.05). Conclusions The perinatal outcomes are relatively better in CIC patients with cervical dilatation degree ≤6.0 cm and cervical length >2.5 cm. The cervical length ≤2.5 cm and cervical dilatation degree >6.0 cm are independent risk factors of pregnancy outcomes. Key words: Cerclage, cervical; Cervical incompetence; Prognosis; Influencing factor
目的探讨急诊宫颈环切术(ECC)治疗宫颈功能不全(CIC)的疗效,并分析影响预后的相关因素。方法回顾性收集2016年6月至2018年6月南阳市第一人民医院ECC治疗的36例CIC患者的临床和病理资料。并对其疗效进行分析。比较不同宫颈扩张程度患者的妊娠结局,分析影响预后的相关因素。结果36例CIC患者经ECC后妊娠周延长(8.55±4.86)周,新生儿存活率为83.33%(30/36)。与宫颈扩张度>6.0 cm组相比,宫颈扩张度≤6.0 cm组妊娠周延长时间更长,流产例数较少,新生儿体重较好,两组差异有统计学意义(P2.5 cm组妊娠周延长时间更长,流产例数较少,新生儿体重较好,两组差异有统计学意义(p6.0 cm是影响妊娠结局的独立危险因素(P2.5 cm);宫颈长度≤2.5 cm、宫颈扩张度>6.0 cm是妊娠结局的独立危险因素。关键词:环扎术;宫颈;颈无能;预后;影响因素
{"title":"Curative effects of emergency cervical cerclage on cervical incompetence and related factors influencing prognosis","authors":"Li Peng, Guiping Zhang, Xinyi Dan","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.011","url":null,"abstract":"Objective \u0000To investigate the curative effects of emergency cervical cerclage (ECC) on cervical incompetence (CIC), and to analyze the related factors influencing prognosis. \u0000 \u0000 \u0000Methods \u0000The clinical and pathological data from 36 CIC patients treated by ECC in Nanyang First People’s Hospital from June 2016 to June 2018 were retrospectively collected. The curative effects were analyzed. The pregnancy outcomes were compared among patients with different cervical dilatation degrees, and the related factors influencing prognosis were analyzed. \u0000 \u0000 \u0000Results \u0000After ECC, gestational weeks of 36 CIC patients were prolonged by (8.55±4.86)weeks, and the neonatal survival rate was 83.33%(30/36). Compared to cervical dilatation degree>6.0 cm group, cervical dilatation degree≤6.0 cm group had longer prolongation time of gestational week, less abortion cases and better neonatal weight, and the difference between the two groups was significant (P 2.5 cm group had longer prolongation time of gestational week, less abortion cases, better neonatal weight, and the difference between the two groups was significant (P 6.0 cm were independent risk factors influencing pregnancy outcomes (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The perinatal outcomes are relatively better in CIC patients with cervical dilatation degree ≤6.0 cm and cervical length >2.5 cm. The cervical length ≤2.5 cm and cervical dilatation degree >6.0 cm are independent risk factors of pregnancy outcomes. \u0000 \u0000 \u0000Key words: \u0000Cerclage, cervical; Cervical incompetence; Prognosis; Influencing factor","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"06 1","pages":"37-40"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85945992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia on advanced cervical cancer 放化疗、腔内近距离放疗和热疗三联疗法治疗晚期宫颈癌的疗效观察
Pub Date : 2020-03-10 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.015
Jia Li, F. Ma
Objective To investigate the effects of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia in the treatment of advanced cervical cancer. Methods A total of 400 patients with advanced cervical cancer admitted to Shanxi Cancer Hospital from July 2011 to June 2016 were selected as the research subjects. They were divided into study group and control group according to the random number table method. Patients in the control group were treated by conventional chemoradiotherapy and intracavitary brachytherapy, and patients in the study group were treated by hyperthermia on the basis of treatment for control group. The curative effects and the changes of leptin and insulin like growth factor 2 (IGF2) in cervical cancer cells before and after treatment were compared between the two groups. After treatment, patients in the two groups were followed up for 3 years, and the tumor-free survival and death of the two groups were recorded. Results The short-term total effective rate of the study group was 74.00% (148/200), higher than the 53.00% (106/200) of the control group (P 0.05). After treatment, the levels of IGF2 and leptin in the study group were lower than those in the control group (P<0.05). During the 3-year follow-up period, the tumor-free survival rate (62.00%, 124/200) and case fatality rate (5.00%, 10/200) in the study group were significantly lower than the 30.50% (61/200) and 17.00%(34/200) in the control group(P<0.05). Conclusions Triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia is effective in the treatment of advanced cervical cancer, which is beneficial to the short-term and long-term clinical effect. Key words: Chemoradiotherapy; Advanced cervical cancer; Intraluminal brachytherapy; Hyperthermia
目的探讨放化疗、腔内近距离放疗和热疗三联疗法治疗晚期宫颈癌的疗效。方法选取2011年7月至2016年6月山西省肿瘤医院收治的400例晚期宫颈癌患者作为研究对象。采用随机数字表法将患者分为研究组和对照组。对照组患者采用常规放化疗和腔内近距离放疗,研究组患者在对照组治疗的基础上采用热疗治疗。比较两组患者治疗前后宫颈癌细胞中瘦素、胰岛素样生长因子2 (IGF2)的变化及疗效。治疗结束后,两组患者随访3年,记录两组患者的无瘤生存和死亡情况。结果研究组短期总有效率为74.00%(148/200),高于对照组53.00% (106/200)(P < 0.05)。治疗后,研究组IGF2、瘦素水平均低于对照组(P<0.05)。3年随访期间,研究组无瘤生存率(62.00%,124/200)和病死率(5.00%,10/200)显著低于对照组的30.50%(61/200)和17.00%(34/200),差异有统计学意义(P<0.05)。结论放化疗+腔内近距离放疗+热疗三联疗法治疗晚期宫颈癌是有效的,有利于近期和远期临床疗效。关键词:放化疗;晚期子宫颈癌;管腔内的近距离放射疗法;高热
{"title":"Effect of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia on advanced cervical cancer","authors":"Jia Li, F. Ma","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.015","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.015","url":null,"abstract":"Objective \u0000To investigate the effects of triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia in the treatment of advanced cervical cancer. \u0000 \u0000 \u0000Methods \u0000A total of 400 patients with advanced cervical cancer admitted to Shanxi Cancer Hospital from July 2011 to June 2016 were selected as the research subjects. They were divided into study group and control group according to the random number table method. Patients in the control group were treated by conventional chemoradiotherapy and intracavitary brachytherapy, and patients in the study group were treated by hyperthermia on the basis of treatment for control group. The curative effects and the changes of leptin and insulin like growth factor 2 (IGF2) in cervical cancer cells before and after treatment were compared between the two groups. After treatment, patients in the two groups were followed up for 3 years, and the tumor-free survival and death of the two groups were recorded. \u0000 \u0000 \u0000Results \u0000The short-term total effective rate of the study group was 74.00% (148/200), higher than the 53.00% (106/200) of the control group (P 0.05). After treatment, the levels of IGF2 and leptin in the study group were lower than those in the control group (P<0.05). During the 3-year follow-up period, the tumor-free survival rate (62.00%, 124/200) and case fatality rate (5.00%, 10/200) in the study group were significantly lower than the 30.50% (61/200) and 17.00%(34/200) in the control group(P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Triple therapy of chemoradiotherapy, intracavitary brachytherapy and hyperthermia is effective in the treatment of advanced cervical cancer, which is beneficial to the short-term and long-term clinical effect. \u0000 \u0000 \u0000Key words: \u0000Chemoradiotherapy; Advanced cervical cancer; Intraluminal brachytherapy; Hyperthermia","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"9 1","pages":"50-53"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87204015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Danzhi Xiaoyao powder on late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels 丹栀逍遥散治疗胎经络不和致迟发性青春期后痤疮的疗效观察
Pub Date : 2020-03-10 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.029
Xinfen Xu
Objective To investigate the clinical effects of Danzhi Xiaoyao powder in the treatment of late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. Methods A retrospective analysis was performed on the clinical data of 72 patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels admitted to Heze Hospital of Traditional Chinese Medicine from March 2016 to September 2018. All patients were divided into two groups according to treatment methods, with 36 cases in each group. Patients in the control group were treated with conventional western medicine, and patients in the observation group were treated with Danzhi Xiaoyao powder. The levels of serum sex hormone, improvement of skin rash and clinical therapeutic effect were compared between the two groups. Results Compared with the preoperative indexes, the serum sex hormone levels and global acne grading system (GAGS) scores in the two groups were lower after treatment, and the indexes in observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The total effective rate of the observation group was 94.44% (34/36), higher than the 72.22% (26/36) of the control group, and the difference was statistically significant (P<0.05). Conclusions Danzhi Xiaoyao powder can effectively reduce the serum sex hormone level and improve the skin rash in the patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. Key words: Delayed acne after puberty caused by disharmony of Conception and Thoroughfare Vessels; Danzhi Xiaoyao powder; Serum sex hormone level; Rash situation
目的观察丹栀逍遥散治疗胎通不整型迟发性青春期后痤疮的临床疗效。方法回顾性分析2016年3月至2018年9月菏泽中医院收治的72例胎通不和谐致迟发性青春期后痤疮患者的临床资料。所有患者根据治疗方法分为两组,每组36例。对照组采用西药常规治疗,观察组采用丹栀逍遥散治疗。比较两组患者血清性激素水平、皮疹改善情况及临床治疗效果。结果与术前指标比较,治疗后两组患者血清性激素水平及痤疮总体评分(GAGS)均降低,且观察组均低于对照组,差异有统计学意义(P<0.05)。观察组总有效率为94.44%(34/36),高于对照组的72.22%(26/36),差异有统计学意义(P<0.05)。结论丹栀逍遥散能有效降低胎通失调型迟发性青春期后痤疮患者血清性激素水平,改善皮疹症状。【关键词】经脉不和致青春期后迟发性痤疮;丹栀逍遥散;血清性激素水平;皮疹情况
{"title":"Effects of Danzhi Xiaoyao powder on late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels","authors":"Xinfen Xu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.029","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.029","url":null,"abstract":"Objective \u0000To investigate the clinical effects of Danzhi Xiaoyao powder in the treatment of late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. \u0000 \u0000 \u0000Methods \u0000A retrospective analysis was performed on the clinical data of 72 patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels admitted to Heze Hospital of Traditional Chinese Medicine from March 2016 to September 2018. All patients were divided into two groups according to treatment methods, with 36 cases in each group. Patients in the control group were treated with conventional western medicine, and patients in the observation group were treated with Danzhi Xiaoyao powder. The levels of serum sex hormone, improvement of skin rash and clinical therapeutic effect were compared between the two groups. \u0000 \u0000 \u0000Results \u0000Compared with the preoperative indexes, the serum sex hormone levels and global acne grading system (GAGS) scores in the two groups were lower after treatment, and the indexes in observation group were lower than those in the control group, and the difference was statistically significant (P<0.05). The total effective rate of the observation group was 94.44% (34/36), higher than the 72.22% (26/36) of the control group, and the difference was statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Danzhi Xiaoyao powder can effectively reduce the serum sex hormone level and improve the skin rash in the patients with late-onset post-pubertal acne caused by disharmony of Conception and Thoroughfare Vessels. \u0000 \u0000 \u0000Key words: \u0000Delayed acne after puberty caused by disharmony of Conception and Thoroughfare Vessels; Danzhi Xiaoyao powder; Serum sex hormone level; Rash situation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"82 1","pages":"97-99"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79963784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Drug resistance and genotypes of Mycobacterium tuberculosis in Datong area 大同地区结核分枝杆菌耐药性及基因型分析
Pub Date : 2020-03-10 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.05.012
C. Wei, Yueping Wang, Shuping Li
Objective To analyze the drug resistance and genotypes of Mycobacterium tuberculosis in Datong area. Methods A total of 120 strains of Mycobacterium tuberculosis isolated in the Fourth People’s Hospital of Datong from January 2018 to January 2019 were collected. Drug sensitivity tests were carried out by proportional method. The genotypes of 120 strains of Mycobacterium tuberculosis were analyzed by polymerase chain reaction (PCR) and spacer oligonucleotide typing (spoligotyping). Results Of the 120 strains of Mycobacterium tuberculosis, 78 strains were sensitive to isoniazid, rifampicin, ethambutol and streptomycin, and 42 strains were resistant to these drugs, with the drug resistance rate of 35.00%. Eighty-three strains (69.17%) were Beijing genotype, 37 strains (30.83%) were non-Beijing genotype. Gender, age, affected lung, history of tuberculosis treatment, strain source, genotyping had no significant effect on drug resistance or genotype of tuberculosis strains (P>0.05). Conclusions Beijing genotype Mycobacterium tuberculosis is a major epidemic strain in Datong region, and no significant correlation is found between drug resistance and genotype of Mycobacterium tuberculosis in Datong area. Key words: Mycobacterium tuberculosis; Drug resistance; Genotype; Analysis
目的分析大同地区结核分枝杆菌的耐药情况及基因型。方法收集2018年1月至2019年1月在大同市第四人民医院分离的120株结核分枝杆菌。采用比例法进行药敏试验。采用聚合酶链反应(PCR)和间隔寡核苷酸分型(spoligotyping)对120株结核分枝杆菌进行基因型分析。结果120株结核分枝杆菌中,异烟肼、利福平、乙胺丁醇、链霉素敏感78株,耐药42株,耐药率为35.00%;北京基因型83株(69.17%),非北京基因型37株(30.83%)。性别、年龄、患肺、结核治疗史、菌株来源、基因分型对结核菌株耐药和基因分型均无显著影响(P>0.05)。结论北京基因型结核分枝杆菌是大同地区主要流行菌株,大同地区结核分枝杆菌耐药与基因型无显著相关性。关键词:结核分枝杆菌;耐药;基因型;分析
{"title":"Drug resistance and genotypes of Mycobacterium tuberculosis in Datong area","authors":"C. Wei, Yueping Wang, Shuping Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.05.012","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.05.012","url":null,"abstract":"Objective \u0000To analyze the drug resistance and genotypes of Mycobacterium tuberculosis in Datong area. \u0000 \u0000 \u0000Methods \u0000A total of 120 strains of Mycobacterium tuberculosis isolated in the Fourth People’s Hospital of Datong from January 2018 to January 2019 were collected. Drug sensitivity tests were carried out by proportional method. The genotypes of 120 strains of Mycobacterium tuberculosis were analyzed by polymerase chain reaction (PCR) and spacer oligonucleotide typing (spoligotyping). \u0000 \u0000 \u0000Results \u0000Of the 120 strains of Mycobacterium tuberculosis, 78 strains were sensitive to isoniazid, rifampicin, ethambutol and streptomycin, and 42 strains were resistant to these drugs, with the drug resistance rate of 35.00%. Eighty-three strains (69.17%) were Beijing genotype, 37 strains (30.83%) were non-Beijing genotype. Gender, age, affected lung, history of tuberculosis treatment, strain source, genotyping had no significant effect on drug resistance or genotype of tuberculosis strains (P>0.05). \u0000 \u0000 \u0000Conclusions \u0000Beijing genotype Mycobacterium tuberculosis is a major epidemic strain in Datong region, and no significant correlation is found between drug resistance and genotype of Mycobacterium tuberculosis in Datong area. \u0000 \u0000 \u0000Key words: \u0000Mycobacterium tuberculosis; Drug resistance; Genotype; Analysis","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"11 1","pages":"41-43"},"PeriodicalIF":0.0,"publicationDate":"2020-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84558024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower limbs 腰椎交感神经节射频热凝治疗下肢神经性疼痛的疗效观察
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.026
Baohui Zhang
Objective To study the clinical effect of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower extremity. Methods A total of 44 cases of patients with neuropathic pain of lower extremity treated in Linfen People’s Hospital from January 2017 to February 2019 were selected as research objects.They were divided into observation group and control group based on single random equalization method, with 22 cases in each group. The control group was treated with conventional chemical mutilation, while the observation group was treated with radiofrequency thermocoagulation of lumbar sympathetic nerve. Preoperative and postoperative pain scores, postoperative quality of life scores and preoperative and postoperative skin temperature changes of lower limbs were compared between the two groups. Results There was no significant difference in skin temperature of lower limbs between the two groups before treatment (P>0.05); at 1, 2 and 3 months after treatment, there was a significant difference in skin temperature of lower limbs (P 0.05). VAS pain scores in the observation group were lower than those in the control group at 1, 2 and 3 months after treatment (P<0.05). Conclusions Radiofrequency thermocoagulation of lumbar sympathetic nerve can relieve pain of patients with neuropathic pain of lower extremity, which is safe. Key words: Sympathetic ganglion; Radiofrequency thermocoagulation; Lower limbs; Neuropathic pain
目的探讨腰交感神经节射频热凝治疗下肢神经性疼痛的临床疗效。方法选取2017年1月至2019年2月临汾市人民医院收治的下肢神经性疼痛患者44例为研究对象。采用单次随机均衡法将患者分为观察组和对照组,每组22例。对照组采用常规化学毁伤治疗,观察组采用腰交感神经射频热凝治疗。比较两组患者术前、术后疼痛评分、术后生活质量评分及术前、术后下肢皮肤温度变化。结果两组患者治疗前下肢皮肤温度比较,差异无统计学意义(P>0.05);治疗后1、2、3个月,两组患者下肢皮肤温度差异有统计学意义(P < 0.05)。观察组患者治疗后1、2、3个月VAS疼痛评分均低于对照组(P<0.05)。结论腰交感神经射频热凝治疗可减轻下肢神经性疼痛,安全可靠。关键词:交感神经节;射频热凝固术;下肢;神经性疼痛
{"title":"Effects of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower limbs","authors":"Baohui Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.026","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.026","url":null,"abstract":"Objective \u0000To study the clinical effect of radiofrequency thermocoagulation of lumbar sympathetic ganglion in the treatment of neuropathic pain of lower extremity. \u0000 \u0000 \u0000Methods \u0000A total of 44 cases of patients with neuropathic pain of lower extremity treated in Linfen People’s Hospital from January 2017 to February 2019 were selected as research objects.They were divided into observation group and control group based on single random equalization method, with 22 cases in each group. The control group was treated with conventional chemical mutilation, while the observation group was treated with radiofrequency thermocoagulation of lumbar sympathetic nerve. Preoperative and postoperative pain scores, postoperative quality of life scores and preoperative and postoperative skin temperature changes of lower limbs were compared between the two groups. \u0000 \u0000 \u0000Results \u0000There was no significant difference in skin temperature of lower limbs between the two groups before treatment (P>0.05); at 1, 2 and 3 months after treatment, there was a significant difference in skin temperature of lower limbs (P 0.05). VAS pain scores in the observation group were lower than those in the control group at 1, 2 and 3 months after treatment (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Radiofrequency thermocoagulation of lumbar sympathetic nerve can relieve pain of patients with neuropathic pain of lower extremity, which is safe. \u0000 \u0000 \u0000Key words: \u0000Sympathetic ganglion; Radiofrequency thermocoagulation; Lower limbs; Neuropathic pain","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"70 1","pages":"85-87"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79936257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of efficacy and safety of laparoscopic versus retropubic radical prostatectomy in the treatment of localized prostate cancer 腹腔镜与耻骨后根治性前列腺切除术治疗局限性前列腺癌的疗效和安全性比较
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.011
Jun Fang, Xin Jiang, Zhenpu Wang, Hongli Zhang
Objective To compare the efficacy and safety of radical prostatectomy by laparoscopic approach and retropubic approach in patients with localized prostate cancer. Methods Thirty-seven patients with localized prostate cancer treated in Zhengzhou People’s Hospital from January 2013 to June 2018 were divided into two groups according to different surgical approaches. Twenty-two cases in control group were treated by posterior pubic approach, and 15 cases in observation group were treated by laparoscopy. The perioperative indexes such as operation time, indwelling catheter time, hospitalization time, intraoperative bleeding volume and pain score were recorded and compared between the two groups. The incidence of complications such as urinary incontinence, anastomotic stricture, urinary leakage and erectile dysfunction in the two groups were higher than those of the two groups. Results After treatment, the observation group had shorter hospital stay compared with the control group, significantly reduced intraoperative bleeding, lower pain score, but longer operation time (P 0.05). Conclusions In the treatment of radical prostatectomy, laparoscopic approach can achieve the effect similar to that of the retropubic approach, and it has minimally invasive advantage, which is beneficial to the postoperative recovery of the patients. Key words: Prostate cancer; Laparoscopy; Radical resection
目的比较腹腔镜根治性前列腺切除术与耻骨后入路治疗局限性前列腺癌的疗效和安全性。方法选取2013年1月至2018年6月郑州市人民医院收治的局限性前列腺癌患者37例,根据手术入路不同分为两组。对照组22例采用耻骨后入路治疗,观察组15例采用腹腔镜治疗。记录两组患者手术时间、留置导尿管时间、住院时间、术中出血量、疼痛评分等围手术期指标并进行比较。两组患者尿失禁、吻合口狭窄、尿漏、勃起功能障碍等并发症发生率均高于两组。结果观察组患者治疗后住院时间短于对照组,术中出血量明显减少,疼痛评分明显降低,但手术时间较对照组延长(P < 0.05)。结论在根治性前列腺切除术的治疗中,腹腔镜入路可达到与耻骨后入路相似的效果,且具有微创优势,有利于患者术后恢复。关键词:前列腺癌;腹腔镜检查;彻底的切除
{"title":"Comparison of efficacy and safety of laparoscopic versus retropubic radical prostatectomy in the treatment of localized prostate cancer","authors":"Jun Fang, Xin Jiang, Zhenpu Wang, Hongli Zhang","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.011","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.011","url":null,"abstract":"Objective \u0000To compare the efficacy and safety of radical prostatectomy by laparoscopic approach and retropubic approach in patients with localized prostate cancer. \u0000 \u0000 \u0000Methods \u0000Thirty-seven patients with localized prostate cancer treated in Zhengzhou People’s Hospital from January 2013 to June 2018 were divided into two groups according to different surgical approaches. Twenty-two cases in control group were treated by posterior pubic approach, and 15 cases in observation group were treated by laparoscopy. The perioperative indexes such as operation time, indwelling catheter time, hospitalization time, intraoperative bleeding volume and pain score were recorded and compared between the two groups. The incidence of complications such as urinary incontinence, anastomotic stricture, urinary leakage and erectile dysfunction in the two groups were higher than those of the two groups. \u0000 \u0000 \u0000Results \u0000After treatment, the observation group had shorter hospital stay compared with the control group, significantly reduced intraoperative bleeding, lower pain score, but longer operation time (P 0.05). \u0000 \u0000 \u0000Conclusions \u0000In the treatment of radical prostatectomy, laparoscopic approach can achieve the effect similar to that of the retropubic approach, and it has minimally invasive advantage, which is beneficial to the postoperative recovery of the patients. \u0000 \u0000 \u0000Key words: \u0000Prostate cancer; Laparoscopy; Radical resection","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"102 1","pages":"35-37"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89153345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of capsule endoscopy in the diagnosis of unexplained gastrointestinal bleeding 胶囊内镜在不明原因消化道出血诊断中的价值
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.021
Ji-ye Li
Objective To investigute the diagnostic value of capsule endoscopy (CE) for unexplained gastrointestinal bleeding (OGIB). Methods Sixty patients with OGIB in General Hospital of Jinmei Group from January 2014 to February 2018 were divided into group A (n=28) and group B (n=32) according to bleeding stop time. The patients in group A underwent CE examination within 3 day stoping bleeding, while the patients in group B 3 d after stoping bleeding. Results The total positive rate of CE in 60 patients was 90%. The proportion of vascular malformation, multiple ulcers or erosion were higher than other types (P<0.05). The positive detection rate of group A was 100%, the posttive detection of group B rate was 81.25%, the difference was significant (P<0.05); the average hospital stay in group A was shorter than that in group B (P<0.05). Conclusions The positive rate of OGIB diagnosis in CE is higher, and performing examination earlier, can get better diagnosis effect, which can provide guidance for clinical treatment, reduce blood transfusion and shorten hospitalization time. Key words: Gastrointestinal bleeding; Capsule endoscopy; Vascular malformation
目的探讨胶囊内镜(CE)对不明原因消化道出血(OGIB)的诊断价值。方法选取2014年1月~ 2018年2月金梅集团总医院收治的60例OGIB患者,根据止血时间分为A组(28例)和B组(32例)。A组患者在止血后3天内行CE检查,B组患者在止血后3天行CE检查。结果60例患者CE总阳性率为90%。血管畸形、多发溃疡或糜烂的比例高于其他类型(P<0.05)。A组阳性检出率为100%,B组阳性检出率为81.25%,差异有统计学意义(P<0.05);A组患者平均住院时间短于B组(P<0.05)。结论CE OGIB诊断阳性率较高,早期检查可获得较好的诊断效果,可指导临床治疗,减少输血,缩短住院时间。关键词:消化道出血;胶囊内窥镜;血管畸形
{"title":"Value of capsule endoscopy in the diagnosis of unexplained gastrointestinal bleeding","authors":"Ji-ye Li","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.021","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.021","url":null,"abstract":"Objective \u0000To investigute the diagnostic value of capsule endoscopy (CE) for unexplained gastrointestinal bleeding (OGIB). \u0000 \u0000 \u0000Methods \u0000Sixty patients with OGIB in General Hospital of Jinmei Group from January 2014 to February 2018 were divided into group A (n=28) and group B (n=32) according to bleeding stop time. The patients in group A underwent CE examination within 3 day stoping bleeding, while the patients in group B 3 d after stoping bleeding. \u0000 \u0000 \u0000Results \u0000The total positive rate of CE in 60 patients was 90%. The proportion of vascular malformation, multiple ulcers or erosion were higher than other types (P<0.05). The positive detection rate of group A was 100%, the posttive detection of group B rate was 81.25%, the difference was significant (P<0.05); the average hospital stay in group A was shorter than that in group B (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The positive rate of OGIB diagnosis in CE is higher, and performing examination earlier, can get better diagnosis effect, which can provide guidance for clinical treatment, reduce blood transfusion and shorten hospitalization time. \u0000 \u0000 \u0000Key words: \u0000Gastrointestinal bleeding; Capsule endoscopy; Vascular malformation","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"10 1","pages":"69-71"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89306024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Value of MRI in the diagnosis of shoulder injury MRI在肩关节损伤诊断中的价值
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.002
Guohui Yang, Yuquan Liang, Tao Li, Jinzhao Jiang, Xinping Shen
Objective To explore the value of MRI in the diagnosis of shoulder joint injury. Methods Fifteen patients with shoulder joint injury confirmed by shoulder arthroscopy admitted to Shenzhen Hospital of Hong Kong University from January 2015 to December 2018 were selected, the clinical data of preoperative routine MRI and Mr shoulder arthrography (MRA) were analyzed retrospectively. Results Arthroscopic results showed that in 15 patients with shoulder joint injury, there were 2 full-thickness rotator cuff tears, 10 partial rotator cuff tears and 3 glenoid lip injuries. The results of MRA were 2 cases, 10 cases and 3 cases, which were consistent with arthroscopic results. Routine MRI diagnosis results: 1 case of rotator cuff full-thickness tear (correct diagnosis rate was 93.3%, missed diagnosis rate was 50.0%, misdiagnosis rate was 0), 12 cases of rotator cuff partial tear (correct diagnosis rate was 86.7%, missed diagnosis rate was 0, misdiagnosis rate was 40.0%), 2 cases of rotator cuff tear complicated with glenoid lip injury (positive diagnosis rate was 93.3%, missed diagnosis rate 33.3%, misdiagnosis rate was 0), of which 2 cases were misdiagnosed as rotator cuff partial tear MRA and arthroscopy showed 1 case of full-thickness rotator cuff tear and 1 case of glenoid lip injury caused by rotator cuff tear. Conclusions Compared with conventional MRI, MR arthrography can improve the diagnosis accuracy of shoulder joint injury and has clinical application value. Key words: Shoulder arthrography; Magnetic resonance imaging; Glenoid lip; Rotator cuff; Injury
目的探讨MRI对肩关节损伤的诊断价值。方法选取2015年1月至2018年12月香港大学深圳医院收治的经肩关节镜确诊的肩关节损伤患者15例,回顾性分析术前常规MRI及Mr肩关节造影(MRA)的临床资料。结果关节镜检查结果显示,15例肩关节损伤患者中,肩袖全层撕裂2例,部分肩袖撕裂10例,肩胛唇损伤3例。MRA结果分别为2例、10例和3例,与关节镜结果一致。MRI常规诊断结果:肩袖全层撕裂1例(正诊率93.3%,漏诊率50.0%,误诊率0),肩袖部分撕裂12例(正诊率86.7%,漏诊率0,误诊率40.0%),肩袖撕裂合并盂唇损伤2例(阳性诊断率93.3%,漏诊率33.3%,误诊率0)。其中2例误诊为肩袖部分撕裂,MRA和关节镜显示1例肩袖全层撕裂,1例肩袖撕裂致肩胛唇损伤。结论与常规MRI相比,MR关节造影能提高肩关节损伤的诊断准确率,具有临床应用价值。关键词:肩关节造影术;磁共振成像;关节窝的唇;肌腱套;受伤
{"title":"Value of MRI in the diagnosis of shoulder injury","authors":"Guohui Yang, Yuquan Liang, Tao Li, Jinzhao Jiang, Xinping Shen","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.002","url":null,"abstract":"Objective \u0000To explore the value of MRI in the diagnosis of shoulder joint injury. \u0000 \u0000 \u0000Methods \u0000Fifteen patients with shoulder joint injury confirmed by shoulder arthroscopy admitted to Shenzhen Hospital of Hong Kong University from January 2015 to December 2018 were selected, the clinical data of preoperative routine MRI and Mr shoulder arthrography (MRA) were analyzed retrospectively. \u0000 \u0000 \u0000Results \u0000Arthroscopic results showed that in 15 patients with shoulder joint injury, there were 2 full-thickness rotator cuff tears, 10 partial rotator cuff tears and 3 glenoid lip injuries. The results of MRA were 2 cases, 10 cases and 3 cases, which were consistent with arthroscopic results. Routine MRI diagnosis results: 1 case of rotator cuff full-thickness tear (correct diagnosis rate was 93.3%, missed diagnosis rate was 50.0%, misdiagnosis rate was 0), 12 cases of rotator cuff partial tear (correct diagnosis rate was 86.7%, missed diagnosis rate was 0, misdiagnosis rate was 40.0%), 2 cases of rotator cuff tear complicated with glenoid lip injury (positive diagnosis rate was 93.3%, missed diagnosis rate 33.3%, misdiagnosis rate was 0), of which 2 cases were misdiagnosed as rotator cuff partial tear MRA and arthroscopy showed 1 case of full-thickness rotator cuff tear and 1 case of glenoid lip injury caused by rotator cuff tear. \u0000 \u0000 \u0000Conclusions \u0000Compared with conventional MRI, MR arthrography can improve the diagnosis accuracy of shoulder joint injury and has clinical application value. \u0000 \u0000 \u0000Key words: \u0000Shoulder arthrography; Magnetic resonance imaging; Glenoid lip; Rotator cuff; Injury","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"52 1","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87474085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of efficacy of caffeine citrate versus aminophylline in the treatment of premature infants with apnea 枸橼酸咖啡因与氨茶碱治疗早产儿呼吸暂停的疗效比较
Pub Date : 2020-02-25 DOI: 10.3760/CMA.J.ISSN.1674-4756.2020.04.034
Jian-ping Zhu
Objective To compare the effect of caffeine citrate and aminophylline in the treatment of premature apnea. Methods A total of 230 premature infants with apnea admitted to Linfen People’s Hospital from January 2013 to December 2018 were randomly divided into two groups according to the random number table method, with 115 cases in each group. Caffeine citrate group was treated with caffeine citrate, and aminophylline group was treated with aminophylline. The related clinical indicators, mental development index score (MDI score), psychomotor development index score (PDI score), complications and adverse reactions were compared between the two groups. Results Respiratory support time, total assisted ventilation time, mechanical ventilation time, nasal intermittent positive pressure ventilation (NIPPV) time, nasal continuous positive airway pressure (nCPAP) time, oxygen therapy time, medication time, hospitalization time and hospitalization cost in the citrate caffeine group were significantly lower than those in the aminophylline group. The corrected MDI scores and PDI scores at 6 months and 12 months were significantly higher than those in the aminophylline group; the incidence of bronchopulmonary dysplasia (BPD), patent ductus arteriosus (PDA) and brain injury was significantly lower than those of the aminophylline group; feeding intolerance, and the incidence of polyuria and hypokalemia were significantly lower than those of the aminophylline group, and the difference were statistically significant (P<0.05). Conclusions Compared with aminophylline, caffeine citrate has more stable effect and higher safety on premature apnea. Key words: Caffeine citrate; Aminophylline; Premature infant; Apnea
目的比较枸橼酸咖啡因与氨茶碱治疗过早呼吸暂停的疗效。方法选取临汾市人民医院2013年1月至2018年12月收治的呼吸暂停早产儿230例,按随机数字表法随机分为两组,每组115例。枸橼酸咖啡因组用枸橼酸咖啡因治疗,氨茶碱组用氨茶碱治疗。比较两组患者相关临床指标、精神发展指数评分(MDI)、精神运动发展指数评分(PDI)、并发症及不良反应情况。结果枸橼酸咖啡因组呼吸支持时间、总辅助通气时间、机械通气时间、鼻间歇正压通气(NIPPV)时间、鼻持续气道正压通气(nCPAP)时间、氧疗时间、用药时间、住院时间、住院费用均显著低于氨茶碱组。6个月和12个月校正后的MDI评分和PDI评分均显著高于氨茶碱组;支气管肺发育不良(BPD)、动脉导管未闭(PDA)及脑损伤发生率显著低于氨茶碱组;喂养不耐受、多尿、低钾血症发生率均显著低于氨茶碱组,差异均有统计学意义(P<0.05)。结论与氨茶碱相比,枸橼酸咖啡因对早期呼吸暂停的疗效更稳定,安全性更高。关键词:枸橼酸咖啡因;氨茶碱;早产儿;呼吸暂停
{"title":"Comparison of efficacy of caffeine citrate versus aminophylline in the treatment of premature infants with apnea","authors":"Jian-ping Zhu","doi":"10.3760/CMA.J.ISSN.1674-4756.2020.04.034","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-4756.2020.04.034","url":null,"abstract":"Objective \u0000To compare the effect of caffeine citrate and aminophylline in the treatment of premature apnea. \u0000 \u0000 \u0000Methods \u0000A total of 230 premature infants with apnea admitted to Linfen People’s Hospital from January 2013 to December 2018 were randomly divided into two groups according to the random number table method, with 115 cases in each group. Caffeine citrate group was treated with caffeine citrate, and aminophylline group was treated with aminophylline. The related clinical indicators, mental development index score (MDI score), psychomotor development index score (PDI score), complications and adverse reactions were compared between the two groups. \u0000 \u0000 \u0000Results \u0000Respiratory support time, total assisted ventilation time, mechanical ventilation time, nasal intermittent positive pressure ventilation (NIPPV) time, nasal continuous positive airway pressure (nCPAP) time, oxygen therapy time, medication time, hospitalization time and hospitalization cost in the citrate caffeine group were significantly lower than those in the aminophylline group. The corrected MDI scores and PDI scores at 6 months and 12 months were significantly higher than those in the aminophylline group; the incidence of bronchopulmonary dysplasia (BPD), patent ductus arteriosus (PDA) and brain injury was significantly lower than those of the aminophylline group; feeding intolerance, and the incidence of polyuria and hypokalemia were significantly lower than those of the aminophylline group, and the difference were statistically significant (P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Compared with aminophylline, caffeine citrate has more stable effect and higher safety on premature apnea. \u0000 \u0000 \u0000Key words: \u0000Caffeine citrate; Aminophylline; Premature infant; Apnea","PeriodicalId":9667,"journal":{"name":"Central Plains Medical Journal","volume":"3 1","pages":"110-113"},"PeriodicalIF":0.0,"publicationDate":"2020-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86447524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Central Plains Medical Journal
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1