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Radiation induced mucositis and its relationship with nutritional status in head and neck cancer patients treated with radiotherapy 癌症放疗后头颈部放射性粘膜炎及其与营养状况的关系
Q4 Nursing Pub Date : 2019-12-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.06.007
Lichuan Zhang, Yujie Wang, B. Zhuang, Hongmei Li, L. Gong, Yanli Wang, Yu Fang, Yan Sun, S. Xiao, B. Zheng
Objective To describe the characteristics of radiation induced mucositis in patients with head and neck cancer (HNC) during radiotherapy, and analyze the effect of radiation induced mucositis on diet patterns and weight change and the influencing factors for radiation induced mucositis. Methods Patients with HNC treated with radiotherapy in one cancer hospital were recruited. Data were collected before, during and at the end of the radiotherapy, which included radiation induced oral and pharyngeal mucositis, pain during eating, diet patterns and weight. Results Two hundred and two patients were completely investigated and 43.5% and 34.2% of the patients suffered from moderate to severe(≥grade 2) oral mucositis and pharyngeal mucositis, respectively during the radiotherapy. At the end of radiotherapy, 53.5% and 51.5% of the patients suffered from moderate to severe oral mucositis and pharyngeal mucositis (≥grade 2), respectively. Oral and pharyngeal mucositis were significantly correlated with pain during eating, diet patterns and weight(P<0.05). Tumor site was the main reason that affected the severity of mucositis(Wald χ2=26.033, 14.216; P<0.001). Conclusion Radiation induced mucositis was gradually aggravated with radiotherapy progress, which is closely related to pain during eating, change of diet patterns and weight loss. The severity of mucositis is related to the tumor site. Measures should be taken to strengthen the management of adverse reactions and nutritional status of patients. Key words: Head and Neck Cancer; Radiation Induced Mucositis; Pain; Diet Pattern; Weight
目的探讨癌症头颈部放疗过程中放射性粘膜炎的特点,分析放射性粘膜炎对饮食结构、体重变化的影响及影响因素。方法选择癌症某医院接受放射治疗的HNC患者。在放射治疗之前、期间和结束时收集数据,包括放射诱导的口腔和咽部粘膜炎、进食过程中的疼痛、饮食模式和体重。结果对222例患者进行了全面的调查,放疗中口腔黏膜炎和咽黏膜炎的发生率分别为43.5%和34.2%。放疗结束时,53.5%和51.5%的患者分别患有中重度口腔粘膜炎和咽粘膜炎(≥2级)。口咽粘膜炎与进食疼痛、饮食方式和体重显著相关(P<0.05)。肿瘤部位是影响粘膜炎严重程度的主要原因(Waldχ2=26.033,14.216;P<0.001),改变饮食模式和减肥。粘膜炎的严重程度与肿瘤部位有关。应采取措施加强对患者不良反应和营养状况的管理。关键词:癌症;辐射引起的粘膜炎;疼痛;饮食模式;重量
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引用次数: 0
Effect of comprehensive feeding intervention on feeding intolerance of premature infants 综合喂养干预对早产儿喂养不耐受的影响
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.008
Du Qinxia, Lihua Luo, Dong-Dong Liu, Qian-qian Wu, Xinya Zhu
Objective To investigate the effect of comprehensive feeding intervention on feeding quality and weight gain of premature infants. Methods Eighty-one premature infants admitted to the neonatal intensive care unit (NICU) of our hospital from September 2016 to December 2018 were selected and randomly divided into the intervention group (n=41) and the control group (n=40). Infants in the control group received routine nursing and infants in the intervention group were given comprehensive feeding intervention on the basis of routine nursing includingimproved Y type gastric tube, gravity tube feeding in prone position, oral movement intervention, colostrum oral immunotherapy and kangaroo nursing. The changes of feeding process were compared between the two groups and the occurrence of feeding intolerance in the two groups was observed. Results The duration of tube feeding and hospital stay were lower in the intervention group than in the control group (P 0.05), but the average daily weight growth rate [g/(kg·d) ] after 1 week and the milk volume [ml/(kg·d)] at 1 week were higher in the intervention group than in the control group(P<0.05). The incidence of gastric retention, abdominal distension and vomiting in the intervention group was lower than that in the control group, but only the difference in the incidence of gastric retention (24.4% vs 47.5%) was statistically significant (P<0.05). The incidence of feeding intolerance was significantly lower in the intervention group than in the control group (24.39% vs 47.50%, P<0.05). Conclusion Comprehensive nursing intervention can shorten the tube feeding time of premature infants, promote the weight growth of premature infants, improve the feeding quality, reduce the incidence of feeding intolerance, and reduce the hospital stay of premature infants, so as to reduce the hospitalization cost, improve the quality of life of premature infants, and increase the satisfaction of parents. Key words: Comprehensive nursing intervention; Premature infant; Feeding intolerance
目的探讨综合喂养干预对早产儿喂养质量和体重增加的影响。方法选择2016年9月至2018年12月在我院新生儿重症监护病房(NICU)住院的早产儿81例,随机分为干预组(n=41)和对照组(n=40)。对照组患儿给予常规护理,干预组患儿在常规护理的基础上给予改良Y型胃管、俯卧位重力管喂养、口腔运动干预、初乳口服免疫治疗及袋鼠式护理等综合喂养干预。比较两组小鼠摄食过程的变化,观察两组小鼠摄食不耐受的发生情况。结果干预组的管饲时间和住院时间均低于对照组(P<0.05),但干预组1周后平均日增重速率[g/(kg·d)]和1周泌乳量[ml/(kg·d)]均高于对照组(P<0.05)。干预组胃潴留、腹胀、呕吐发生率均低于对照组,仅胃潴留发生率(24.4% vs 47.5%)差异有统计学意义(P<0.05)。干预组喂养不耐受发生率明显低于对照组(24.39% vs 47.50%, P<0.05)。结论综合护理干预可缩短早产儿管饲时间,促进早产儿体重增长,提高喂养质量,减少喂养不耐受发生率,减少早产儿住院时间,从而降低住院费用,提高早产儿的生活质量,提高家长满意度。关键词:综合护理干预;早产儿;喂养不耐受
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引用次数: 0
Effects of micronutrients supplementation on plasma homocysteine level and global cognitive function among older adults in long-term care facilities: a randomized controlled study 补充微量营养素对长期护理机构中老年人血浆同型半胱氨酸水平和整体认知功能的影响:一项随机对照研究
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.001
Min Zhao, Zhuo Li, Zhuming Jiang, W. Kang, Kang Yu, Q. Lu, Xiaoxi Li, Xianna Zhang, Hai Fang, Yang Wang, Wei Li, Shenggao Han, R. Jing, Zhenshu Li, Dali Sun, Bin Zhao
Objective To investigate the effects of micronutrient supplementation for the elderly on plasma homocysteine level and cognitive function in institutional older adults. Methods A total of 98 older adults with the score≤11 by mini nutritional assessment short-form aged 65-100 years were enrolled and assigned to either intervention group or control group (n=49 each), with either a package of micronutrient pack or placebo daily, for three months. Fasting blood samples were collected both at baseline and the end of study to detect serum vitamin B12, folate and plasma homocysteine (Hcy) concentrations. Global cognitive function was assessed using the mini-mental state examination (MMSE). The paired t test was used to compare the continuous variables between the two groups after intervention. The relationship between changes in MMSE score and changes in plasma Hcy concentrations was examined by least-squares linear regression. Results Eighty-two patients completed the study, and 17 patients withdrew from the study due to diarrhea and hospital discharge with the drop rate of 17.3%. Compared to the control group, concentrations of serum vitamin B12 (128.8±34.8 vs 13.3±16.0 pmol/L, P=0.003) and folate (21.1±1.6 vs 0.6±0.5 nmol/L, P<0.01) significantly increased in the intervention group over 3-month supplementation, while plasma Hcy levels were remarkably reduced (-5.3±0.7 vs 1.7±0.3 μmol/L, P<0.01). The incidences of deficiency of folate, deficiency of serum vitamin B12and high Hcy all decreased in intervention group. Although individual item scores in MMSE were not changed markedly, change of total MMSE score in intervention group were higher than that in the control group (1.2±3.0 vs -0.2±2.5, P<0.05). Conclusions The supplementation of the micronutrient pack in long-term care facilities can reduce the incidence of hyperhomocysteinemia, and improve the total MMSE score. Key words: Micronutrient; Older adults; Homocysteine; Cognitive function
目的探讨老年人补充微量营养素对住院老年人血浆同型半胱氨酸水平和认知功能的影响。方法将98名年龄在65-100岁的老年人纳入干预组或对照组(每组49人),每天服用一包微量营养素包或安慰剂,为期三个月。在基线和研究结束时采集空腹血样,以检测血清维生素B12、叶酸和血浆同型半胱氨酸(Hcy)浓度。使用简易精神状态检查(MMSE)评估整体认知功能。配对t检验用于比较干预后两组之间的连续变量。MMSE评分的变化与血浆Hcy浓度的变化之间的关系通过最小二乘线性回归进行检验。结果82例患者完成了研究,17例患者因腹泻和出院退出研究,下降率为17.3%。与对照组相比,干预组的血清维生素B12浓度(128.8±34.8 vs 13.3±16.0 pmol/L,P=0.003)和叶酸浓度(21.1±1.6 vs 0.6±0.5 nmol/L,P<0.01)在补充3个月后显著升高,干预组血浆Hcy水平显著降低(-5.3±0.7 vs 1.7±0.3μmol/L,P<0.01)。虽然MMSE单项评分变化不大,但干预组MMSE总分变化明显高于对照组(1.2±3.0 vs-0.2±2.5,P<0.05)。结论长期护理机构补充微量营养素包可降低高同型半胱氨酸血症的发生率,提高MMSE总分。关键词:微量营养素;老年人;同型半胱氨酸;认知功能
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引用次数: 0
Perioperative weight loss and its influencing factors in patients with colorectal cancer 结直肠癌患者围手术期体重减轻及其影响因素
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.006
Yaqin Chu, Jian Zhao, Zhiwei Jiang
Objective To investigate the perioperative weight loss and its influencing factors in patients with colorectal cancer, and to provide evidence for the development and management of perioperative nutritional support strategies. Methods Ninety-one patients with colorectal cancer were enrolled and divided into observation group (n=61) with the degree of weight loss less than 5% of preoperative weight and control group (n=30) with the degree of weight loss more than 5% of preoperative weight. Change of body composition and factors of weight loss in patients with colorectal cancer were compared between the two groups by single factor and multivariate analysis. Results Ninety-one patients with colorectal cancer had the average weight loss of 2.0 kg. Of perioperative changes in body composition, the degree of body fat, muscle mass and protein group decreased statistically (P<0.05). Univariate analysis showed that the age, intraoperative blood loss and postoperative oral nutrition intake compliance were the risk factors for the degree of weight loss in patients with colorectal cancer after the operation. Multivariate logistic regression analysis showed that the intraoperative blood loss was an independent influencing factor for the degree of postoperative weight loss in patients with colorectal cancer (P<0.05). Conclusion Age, intraoperative blood loss and postoperative oral nutritional intake compliance may affect the degree of weight loss during perioperative period. Intraoperative blood loss is an independent risk factor affecting the degree of weight loss during perioperative period. In future clinical research and practice, minimally invasive and accurate surgical treatment should be strengthened, the amount of intraoperative blood loss and surgical trauma should be reduced, and the postoperative oral nutrition intake of patients should be paid attention, especially for elderly patients. Personalized dietary guidance and management for different groups should be conducted, and perioperative nutritional status of patients should be improved. Key words: Colorectal cancer; Weight loss; Body composition; Enhanced recovery after surgery
目的探讨癌症患者围手术期体重减轻及其影响因素,为围手术期营养支持策略的制定和管理提供依据。方法将90例癌症患者分为观察组(n=61)和对照组(n=30),观察组体重减轻程度小于术前体重的5%。采用单因素和多因素分析方法,比较两组大肠癌患者的身体成分变化和体重减轻因素。结果9例癌症患者平均体重减轻2.0kg,围手术期身体成分变化中,体脂、肌肉、蛋白质组含量均明显下降(P<0.05),术中出血量和术后口服营养摄入依从性是影响癌症患者术后体重减轻程度的危险因素。多因素logistic回归分析显示术中出血量是影响癌症患者术后体重减轻程度的独立因素(P<0.05)。术中失血是影响围手术期体重减轻程度的独立危险因素。在未来的临床研究和实践中,应加强微创精确的手术治疗,减少术中失血量和手术创伤,并注意患者术后口腔营养的摄入,尤其是老年患者。应针对不同人群进行个性化的饮食指导和管理,改善患者围手术期的营养状况。关键词:结直肠癌癌症;减肥;身体成分;术后恢复增强
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引用次数: 0
Corresponding Application of quality control circle in reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy 相应的品管圈在降低胃癌化疗患者中重度营养不良发生率中的应用
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.003
Q. Mou, Hongjuan Li, Li Linjuan
Objective To explore the effect of quality control circle(QCC)on reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy. Methods Before the activity (February to March 2016), 146 gastric cancer patients under chemotherapy were selected as the control group, and regular nutrition nursing (dietary guidance and regular nutrition-related health lectures) was given. After the activity (February to March 2017), 139 gastric cancer patients under chemotherapy were selected as QCC group, and the standard intervention of quality control circle was implemented. The nutritional status of patients before and after improvement was compared. Results After finding the cause and formulating and implementing the measures, the 24-hour consultation rate, the incomplete remission rate of nausea/vomiting, the incidence of cancer anorexia, and the rate of missed visits in QCC group were significantly different with those in control group (P<0.05). The incidence of moderate or severe malnutrition was 16.55% in QCC group and 65.07% in control group, and the difference was statistically significant (P<0.01). Conclusions The quality control circle activity can effectively reduce the incidence of moderate or severe malnutrition and improve the quality of life in gastric cancer patients under chemotherapy. It can also improve the self-discipline and initiative of medical staff and improve the quality of medical care. Key words: Quality control circle; Gastric cancer; Chemotherapy; Moderate or severe malnutrition
目的探讨质量控制圈(QCC)对降低胃癌化疗患者中重度营养不良发生率的作用。方法选取活动前(2016年2月至3月)146例胃癌化疗患者作为对照组,给予定期营养护理(饮食指导及定期营养相关健康讲座)。活动结束后(2017年2月至3月),选取139例正在化疗的胃癌患者作为QCC组,实施品管圈标准干预。比较改善前后患者的营养状况。结果发现原因并制定实施措施后,QCC组患者24小时问诊率、恶心/呕吐不完全缓解率、癌性厌食症发生率、漏诊率与对照组比较差异均有统计学意义(P<0.05)。QCC组中重度营养不良发生率为16.55%,对照组为65.07%,差异有统计学意义(P<0.01)。结论质控圈活动可有效降低胃癌化疗患者中、重度营养不良发生率,提高患者生活质量。提高医务人员的自律性和主动性,提高医疗服务质量。关键词:品管圈;胃癌;化疗;中度或重度营养不良
{"title":"Corresponding Application of quality control circle in reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy","authors":"Q. Mou, Hongjuan Li, Li Linjuan","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.003","url":null,"abstract":"Objective \u0000To explore the effect of quality control circle(QCC)on reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy. \u0000 \u0000 \u0000Methods \u0000Before the activity (February to March 2016), 146 gastric cancer patients under chemotherapy were selected as the control group, and regular nutrition nursing (dietary guidance and regular nutrition-related health lectures) was given. After the activity (February to March 2017), 139 gastric cancer patients under chemotherapy were selected as QCC group, and the standard intervention of quality control circle was implemented. The nutritional status of patients before and after improvement was compared. \u0000 \u0000 \u0000Results \u0000After finding the cause and formulating and implementing the measures, the 24-hour consultation rate, the incomplete remission rate of nausea/vomiting, the incidence of cancer anorexia, and the rate of missed visits in QCC group were significantly different with those in control group (P<0.05). The incidence of moderate or severe malnutrition was 16.55% in QCC group and 65.07% in control group, and the difference was statistically significant (P<0.01). \u0000 \u0000 \u0000Conclusions \u0000The quality control circle activity can effectively reduce the incidence of moderate or severe malnutrition and improve the quality of life in gastric cancer patients under chemotherapy. It can also improve the self-discipline and initiative of medical staff and improve the quality of medical care. \u0000 \u0000 \u0000Key words: \u0000Quality control circle; Gastric cancer; Chemotherapy; Moderate or severe malnutrition","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"27 1","pages":"276-280"},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43789624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice of linear quality control on manually compounded total nutrient admixtures 人工配制全营养外加剂线性质量控制的实践
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.010
Zhang Jianzhong, Lao Donghui, Yao Bangxin, Jiang-hua Yi, Yang Chun, Wu Guohao, Lv Qianzhou
Objective To establish a quality control model ensuring good stability and compatibility of manually compounded total nutrient admixtures (TNA). Methods A parenteral nutrition medication order entry system was establish for standardizing nutritional medication usage and supporting physician's TNA prescribing. TNA medication orders were reviewed by pharmacists for validating the stability and compatibility. TNAs were compounded by pharmacists in a standard way following "four factors of sterile compounding" . The goal of quality control was achieved by establishment of the preliminary standard. Results The quality of manually compounded total nutrient admixtures achieved the goal since pharmacy intravenous admixture service (PIVAS) started on 2003. Conclusions The quality of TNA is well assured while manually compounded by pharmacists in PIVAS. Key words: Total nutrient admixtures; Pharmacist; Pharmacy intravenous admixture service
目的建立确保人工配制的全营养掺合料具有良好稳定性和相容性的质量控制模型。方法建立肠外营养医嘱录入系统,规范营养用药,支持医师开具TNA处方。药剂师对TNA医嘱进行审查,以验证其稳定性和兼容性。TNA由药剂师按照“无菌配制的四个因素”的标准方式配制。质量控制的目标是通过建立初步标准来实现的。结果自2003年开始提供静脉药物掺合剂服务以来,人工配制的全营养掺合剂的质量达到了预期目标。结论药剂师在PIVAS中手工配制TNA,可保证TNA的质量。关键词:全营养外加剂;药剂师;药房静脉混合用药服务
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引用次数: 0
Effects of oral nutritional supplements on body weight and life qualityin post-discharge patients with gastricor colorectal cancer: A prospective randomized controlled clinical trial 口服营养补充剂对胃大肠癌癌症出院后患者体重和生活质量的影响:一项前瞻性随机对照临床试验
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.002
Yi Jiang, Q. Meng, Shanjun Tan, Qi Zhang, Zhen Yu, Xinping Zhang
Objective To investigate the effect of oral nutritional supplements(ONS) on body weight loss and life quality in post-discharge patients with gastric and colorectal cancer. Methods All the enrolled post-operative gastric or colorectal cancer patients were randomly divided into ONS group and control group. Body weight loss, middle arm circumference, triceps skinfold thickness and right-hand grip strength were measured and the Karnofsky score, ECOG score and QOL score were calculated 3 months after the discharge. Results The body weight loss of gastric cancer patients was lower in ONS group than in control group since 2 months after discharge.(2 months after discharge: 1.65±2.11vs. 2.70±1.90 kg, t=-2.385 3, P=0.019 3; 3 months after discharge: 1.95±2.75vs. 3.67±2.29 kg, t=-3.134 7, P=0.002 4), There was no difference of body weight loss between two groups in colorectal cancer patients. The middle arm circumference, triceps skinfold thicknessand right-hand grip strength showed no statistic difference between two groups both in gastric and colorectal cancer patients. The Karnofsky score(56.82±13.65%vs. 51.71±9.72%, t=2.014 8, P=0.047 2) and QOL score(41.91±6.92 vs. 38.39±8.77, t=2.059 7, P=0.042 6) were higher in ONS group than in control group in gastric cancer patients. While all 3 types of scores had no difference between two groups in colorectal cancer patients. Conclusion ONS can efficiently reduce the body weight loss and improve the performance status and life qualityin post-discharge gastric cancer patients, but not in colorectal cancer patients. Key words: Oral nutritional supplement; Gastric malignancy; Colorectal malignancy
目的探讨口服营养补充剂(ONS)对癌症患者出院后体重减轻和生活质量的影响。方法所有入选的癌症术后患者随机分为ONS组和对照组。出院后3个月测量体重减轻、中臂围、三头肌皮褶厚度和右手握力,并计算Karnofsky评分、ECOG评分和QOL评分。结果自出院2个月以来,ONS组癌症患者的体重减轻明显低于对照组。(出院后2个月:1.65±2.11vs.270±1.90kg,t=-2.3853,P=0.019 3;出院后3个月:1.95±2.75vs3.67±2.29kg,t=-3.1347,P=0.002 4),癌症患者两组体重减轻无差异。癌症组和结直肠癌组的中臂围、三角肌皮褶厚度和右手握力无统计学差异。癌症患者的Karnofsky评分(56.82±13.65%对51.71±9.72%,t=2.014 8,P=0.047 2)和QOL评分(41.91±6.92对38.39±8.77,t=2.059 7,P=0.042 6)高于对照组。而癌症患者的3种评分在两组之间没有差异。结论ONS能有效地减轻癌症患者出院后的体重减轻,改善患者的工作状态和生活质量,但对癌症患者无效。关键词:口服营养补充剂;胃恶性肿瘤;结肠恶性肿瘤
{"title":"Effects of oral nutritional supplements on body weight and life qualityin post-discharge patients with gastricor colorectal cancer: A prospective randomized controlled clinical trial","authors":"Yi Jiang, Q. Meng, Shanjun Tan, Qi Zhang, Zhen Yu, Xinping Zhang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.002","url":null,"abstract":"Objective \u0000To investigate the effect of oral nutritional supplements(ONS) on body weight loss and life quality in post-discharge patients with gastric and colorectal cancer. \u0000 \u0000 \u0000Methods \u0000All the enrolled post-operative gastric or colorectal cancer patients were randomly divided into ONS group and control group. Body weight loss, middle arm circumference, triceps skinfold thickness and right-hand grip strength were measured and the Karnofsky score, ECOG score and QOL score were calculated 3 months after the discharge. \u0000 \u0000 \u0000Results \u0000The body weight loss of gastric cancer patients was lower in ONS group than in control group since 2 months after discharge.(2 months after discharge: 1.65±2.11vs. 2.70±1.90 kg, t=-2.385 3, P=0.019 3; 3 months after discharge: 1.95±2.75vs. 3.67±2.29 kg, t=-3.134 7, P=0.002 4), There was no difference of body weight loss between two groups in colorectal cancer patients. The middle arm circumference, triceps skinfold thicknessand right-hand grip strength showed no statistic difference between two groups both in gastric and colorectal cancer patients. The Karnofsky score(56.82±13.65%vs. 51.71±9.72%, t=2.014 8, P=0.047 2) and QOL score(41.91±6.92 vs. 38.39±8.77, t=2.059 7, P=0.042 6) were higher in ONS group than in control group in gastric cancer patients. While all 3 types of scores had no difference between two groups in colorectal cancer patients. \u0000 \u0000 \u0000Conclusion \u0000ONS can efficiently reduce the body weight loss and improve the performance status and life qualityin post-discharge gastric cancer patients, but not in colorectal cancer patients. \u0000 \u0000 \u0000Key words: \u0000Oral nutritional supplement; Gastric malignancy; Colorectal malignancy","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"27 1","pages":"271-275"},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41746270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease 基于临床护理路径的营养支持对老年阿尔茨海默病住院患者营养状况和生活质量的影响
Q4 Nursing Pub Date : 2019-10-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.05.005
Caiyun Liu, Hongdi Du, Wei Li, Xiaoxuan Liu
Objective To explore the effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease (AD). Methods A total of 101 elderly inpatients with AD who met the criteria of the protocol were consecutively enrolled and randomly divided to study group receiving nutritional support based on clinical nursing pathway for two months (n=51) and control group receiving routine nutritional management for 2 months (n=50). Nutritional risk and quality of life were measured by nutritional risk screening 2002 (NRS 2002) and Quality of Life-Alzheimer's Disease Scale (QOL-AD) respectively before and after nutritional support. Results Baseline data were comparable between the two groups (all P>0.05). After 2-month nutritional support, compared to the control, the incidence of nutritional risk (36.0% vs 17.6%, P=0.037) and undernutrition (26.0% vs 9.8%, P=0.033) decreased significantly in study group. The score of quality of life in study group were significant higher than that of control group (35.73±5.85 vs 30.76±6.14, P=0.023). Conclusion The nutritional support based on clinical nursing pathway is helpful to improve the nutritional status and quality of life in elderly hospitalized patients with AD. Key words: Alzheimer disease; Elderly inpatients; Clinical nursing pathway; Nutritional support; Nutritional risk screening; Quality of life
目的探讨基于临床护理路径的营养支持对老年阿尔茨海默病住院患者营养状况和生活质量的影响。方法将符合本方案标准的101例老年AD住院患者随机分为研究组(n=51)和对照组(n=50),研究组接受基于临床护理路径的营养支持2个月,对照组接受常规营养管理2个月。分别在营养支持前后通过营养风险筛查2002(NRS 2002)和生活质量阿尔茨海默病量表(QOL-AD)测量营养风险和生活质量。结果两组的基线数据具有可比性(均P>0.05)。与对照组相比,营养支持2个月后,研究组的营养风险发生率(36.0%vs 17.6%,P=0.037)和营养不良发生率(26.0%vs 9.8%,P=0.033)显著下降。研究组的生活质量评分显著高于对照组(35.73±5.85 vs 30.76±6.14,P=0.023)。结论基于临床护理路径的营养支持有助于改善老年住院AD患者的营养状况和生活质量;老年住院患者;临床护理路径;营养支持;营养风险筛查;生活质量
{"title":"Effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease","authors":"Caiyun Liu, Hongdi Du, Wei Li, Xiaoxuan Liu","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.005","url":null,"abstract":"Objective \u0000To explore the effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease (AD). \u0000 \u0000 \u0000Methods \u0000A total of 101 elderly inpatients with AD who met the criteria of the protocol were consecutively enrolled and randomly divided to study group receiving nutritional support based on clinical nursing pathway for two months (n=51) and control group receiving routine nutritional management for 2 months (n=50). Nutritional risk and quality of life were measured by nutritional risk screening 2002 (NRS 2002) and Quality of Life-Alzheimer's Disease Scale (QOL-AD) respectively before and after nutritional support. \u0000 \u0000 \u0000Results \u0000Baseline data were comparable between the two groups (all P>0.05). After 2-month nutritional support, compared to the control, the incidence of nutritional risk (36.0% vs 17.6%, P=0.037) and undernutrition (26.0% vs 9.8%, P=0.033) decreased significantly in study group. The score of quality of life in study group were significant higher than that of control group (35.73±5.85 vs 30.76±6.14, P=0.023). \u0000 \u0000 \u0000Conclusion \u0000The nutritional support based on clinical nursing pathway is helpful to improve the nutritional status and quality of life in elderly hospitalized patients with AD. \u0000 \u0000 \u0000Key words: \u0000Alzheimer disease; Elderly inpatients; Clinical nursing pathway; Nutritional support; Nutritional risk screening; Quality of life","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":"27 1","pages":"287-292"},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49509695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Effects of sarcopenia on the risks of osteoporosis and fragility fractures among community-dwelling middle and old age people: a systematic review and meta-analysis 少肌症对社区中老年人骨质疏松和脆性骨折风险的影响:一项系统综述和荟萃分析
Q4 Nursing Pub Date : 2019-08-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.04.002
Min Cui, Kang Yu, Chun-wei Li, Fang Wang
Objective To explore the relationship between sarcopenia and the risks of osteoporosis and fragility fractures among community-dwelling middle and old people (≥50 years). Methods OVID/Medline, Pubmed, EMBASE, Cochrane Library, Web of Science (SCI), China National Knowledge Infrastructure (CNKI), and Chinese WanFang Database were searched systematically for literatures related to the relationship between sarcopenia and osteoporosis and fragility fractures from January 1987 to July 2018. The searched literatures were screened based on the inclusion and exclusion criteria. The quality of the literatures were evaluated by using the risk assessment tool NOS (Newcastle-Ottawa Scale) and AHRQ (Agency for Healthcare Research and Quality). Meta-regression analysis was used to explore the cause of heterogeneity between studies. The subgroup analysis was used to assess the differences in the risk of osteoporosis based on the important characteristic variables, such as gender, ethnicity, age, diagnostic criteria of sarcopenia, and outcome type. Sensitivity analysis and trim and fill method were conducted to test the stability of the results of this Meta-analysis. Data collected and summarized by Stata 12.2 software. Results A total of 23 studies in line with quality requirements were included eventually, including 56, 544 subjects. The results of this Meta-analysis were relatively robust. Compared with non-sarcopenia, the relative risk (RR) for osteoporosis among subjects with sarcopenia was 1.61 (95% CI: 1.42~1.82, P<0.000 01). Especially, compared with postmenopausal women RR=1.37 (95% CI: 1.23-1.53, P<0.000 1) and yellow race RR=1.53 (95% CI: 1.34-1.75, P<0.000 1), sarcopenia had a higher impact trend on the risk of osteoporosis in older men RR=2.26 (95% CI: 1.71-2.98, P<0.000 1) and Caucasian RR=2.03 (95% CI: 1.46-2.81, P<0.000 1). Conclusion Among community-dwelling middle and old aged people(≥50 year), sarcopenia increases the risk of osteoporosis and fragility fracture by 61% and 59% -61% significantly, respectively. Middle and old aged people should be prevented and screened early for sarcopenia, which attributes to identify high risk groups of fragile fractures and reduce the risk of adverse outcomes. Key words: Sarcopenia; Osteoporosis; Fragility fractures; Meta-analysis
目的探讨社区中老年人(≥50岁)少肌症与骨质疏松和脆性骨折风险的关系。方法系统检索1987年1月至2018年7月期间,OVID/Medline、Pubmed、EMBASE、Cochrane Library、Web of Science(SCI)、中国知网(CNKI)和中国万方数据库中有关少肌症与骨质疏松和脆性骨折关系的文献。根据纳入和排除标准对检索到的文献进行筛选。使用风险评估工具NOS(Newcastle Ottawa量表)和AHRQ(Agency for Healthcare Research and quality)对文献质量进行评估。Meta回归分析用于探讨研究之间异质性的原因。亚组分析用于根据重要的特征变量,如性别、种族、年龄、少肌症的诊断标准和结果类型,评估骨质疏松症风险的差异。采用敏感性分析和修剪填充法来检验该荟萃分析结果的稳定性。Stata 12.2软件收集和汇总的数据。结果最终纳入符合质量要求的23项研究,包括56444名受试者。该荟萃分析的结果相对稳健。与非少肌症相比,少肌症受试者患骨质疏松症的相对风险(RR)为1.61(95%CI:1.42~1.82,P<0.01)。特别是,与绝经后女性RR=1.37(95%CI:1.23-1.53,P<0.0001)和黄种RR=1.53(95%CI:1.34-1.75,P<0.0001。结论在社区居住的中老年人(≥50岁)中,少肌症可使骨质疏松症和脆性骨折的风险分别显著增加61%和59%-61%。中老年人应尽早预防和筛查少肌症,这有助于识别脆弱骨折的高危人群并降低不良后果的风险。关键词:Sarcopenia;骨质疏松症;脆性骨折;Meta分析
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引用次数: 0
A comparative study of the respiratory indirect calorimetry and HB coefficient method for the guidance of the target energy in patients with sepsis 呼吸间接量热法和HB系数法指导败血症患者靶能量的比较研究
Q4 Nursing Pub Date : 2019-08-30 DOI: 10.3760/CMA.J.ISSN.1674-635X.2019.04.007
Xiaojuan Yang, Jun Zhang, Lijuan Wang
Objective To explore the effects of nutritional supports following target energy measured by respiratory indirect calorimetry and HB coefficient method respectively on the nutrition and immune indexes of patients with sepsis. Methods A prospective comparative study of 60 patients with sepsis who was suitable for nutritional support and respiratory indirect calorimetry in the intensive care unit (ICU) of the hospital from January 2015 to October 2015 was conducted. Resting Energy Expenditure (REE) was measured simultaneously by respiratory indirect calorimetry (n=30) and HB coefficient (Harris-Benedict formula×stress coefficient, n=30) in patients with sepsis and the nutritional support was given according to the MREE measured by the two methods. The nutritional and immune indexes were obtained at 0 day, 3 day, 7 day, and 14 day after nutritional support. The nutritional and immune indexes at 0 day were considered as the baseline and the differences in the nutritional and immune indexes between the baseline and 3 day, 7 day and 14 day were expressed as a "Δ". Values of Δ were compared between the two goups. Results With nutritional support for 3 days, Δalbumin, Δ prealbumin, Δthe total T lymphocytes, Δassist/induction of T cells and ΔIgG were higher in the respiratory indirect calorimetry group than in the HB coefficient group (P<0.05). With nutritional support for 7 days, Δalbumin, ΔT lymphocytes, ΔIgM were higher in the respiratory indirect calorimetry group than in the HB coefficient group (P<0.05). With nutritional support for 14 days, Δtransferrin, Δsuppression/cytotoxic T cells, ΔIgG, ΔIgA, ΔC3 andΔC4 were higher in the respiratory indirect calorimetry group than in the HB coefficient group(P<0.05). Conclusion Nutritional support with REE measured by respiratory indirect calorimetry in patients with sepsis is more effective on nutritional and immune related indexes improvement have different degrees of improvement, thus respiratory indirect calorimetry is more suitable to guide the target energy of sepsis patients. Key words: Sepsis; Target energy; Respiratory indirect calorimetry; HB coefficient; Nutrition
目的探讨呼吸间接量热法和HB系数法分别测定目标能量后给予营养支持对脓毒症患者营养和免疫指标的影响。方法对2015年1月至2015年10月在该院重症监护室(ICU)收治的60例适合营养支持及呼吸间接量热法治疗的脓毒症患者进行前瞻性比较研究。采用呼吸间接量热法(n=30)和HB系数(Harris-Benedict formula×stress系数,n=30)同时测量脓毒症患者的静息能量消耗(REE),并根据两种方法测得的REE给予营养支持。分别于营养支持后第0天、第3天、第7天和第14天测定各组的营养和免疫指标。以第0天的营养和免疫指标为基线,将基线与第3天、第7天、第14天的营养和免疫指标差异用“Δ”表示。比较两组间Δ值。结果营养支持3 d时,呼吸间接量热组患者Δalbumin、Δ前白蛋白、Δthe总T淋巴细胞、Δassist/诱导T细胞和ΔIgG均高于HB系数组(P<0.05)。营养支持7 d时,呼吸间接量热组Δalbumin、ΔT淋巴细胞、ΔIgM高于HB系数组(P<0.05)。营养支持14 d时,呼吸间接量热组患者的Δtransferrin、Δsuppression/细胞毒性T细胞、ΔIgG、ΔIgA、ΔC3 andΔC4均高于HB系数组(P<0.05)。结论呼吸间接量热法测量REE对脓毒症患者的营养支持更有效,对其营养及免疫相关指标的改善均有不同程度的改善,因此呼吸间接量热法更适合指导脓毒症患者的目标能量。关键词:脓毒症;目标能量;呼吸间接量热法;HB系数;营养
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引用次数: 0
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中华临床营养杂志
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