中华临床营养杂志最新文献

{"title":"Radiation induced mucositis and its relationship with nutritional status in head and neck cancer patients treated with radiotherapy","authors":"Lichuan Zhang, Yujie Wang, B. Zhuang, Hongmei Li, L. Gong, Yanli Wang, Yu Fang, Yan Sun, S. Xiao, B. Zheng","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.06.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.06.007","url":null,"abstract":"Objective \u0000To describe the characteristics of radiation induced mucositis in patients with head and neck cancer (HNC) during radiotherapy, and analyze the effect of radiation induced mucositis on diet patterns and weight change and the influencing factors for radiation induced mucositis. \u0000 \u0000 \u0000Methods \u0000Patients with HNC treated with radiotherapy in one cancer hospital were recruited. Data were collected before, during and at the end of the radiotherapy, which included radiation induced oral and pharyngeal mucositis, pain during eating, diet patterns and weight. \u0000 \u0000 \u0000Results \u0000Two hundred and two patients were completely investigated and 43.5% and 34.2% of the patients suffered from moderate to severe(≥grade 2) oral mucositis and pharyngeal mucositis, respectively during the radiotherapy. At the end of radiotherapy, 53.5% and 51.5% of the patients suffered from moderate to severe oral mucositis and pharyngeal mucositis (≥grade 2), respectively. Oral and pharyngeal mucositis were significantly correlated with pain during eating, diet patterns and weight(P<0.05). Tumor site was the main reason that affected the severity of mucositis(Wald χ2=26.033, 14.216; P<0.001). \u0000 \u0000 \u0000Conclusion \u0000Radiation induced mucositis was gradually aggravated with radiotherapy progress, which is closely related to pain during eating, change of diet patterns and weight loss. The severity of mucositis is related to the tumor site. Measures should be taken to strengthen the management of adverse reactions and nutritional status of patients. \u0000 \u0000 \u0000Key words: \u0000Head and Neck Cancer; Radiation Induced Mucositis; Pain; Diet Pattern; Weight","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41502268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of comprehensive feeding intervention on feeding intolerance of premature infants","authors":"Du Qinxia, Lihua Luo, Dong-Dong Liu, Qian-qian Wu, Xinya Zhu","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.008","url":null,"abstract":"Objective \u0000To investigate the effect of comprehensive feeding intervention on feeding quality and weight gain of premature infants. \u0000 \u0000 \u0000Methods \u0000Eighty-one premature infants admitted to the neonatal intensive care unit (NICU) of our hospital from September 2016 to December 2018 were selected and randomly divided into the intervention group (n=41) and the control group (n=40). Infants in the control group received routine nursing and infants in the intervention group were given comprehensive feeding intervention on the basis of routine nursing includingimproved Y type gastric tube, gravity tube feeding in prone position, oral movement intervention, colostrum oral immunotherapy and kangaroo nursing. The changes of feeding process were compared between the two groups and the occurrence of feeding intolerance in the two groups was observed. \u0000 \u0000 \u0000Results \u0000The duration of tube feeding and hospital stay were lower in the intervention group than in the control group (P 0.05), but the average daily weight growth rate [g/(kg·d) ] after 1 week and the milk volume [ml/(kg·d)] at 1 week were higher in the intervention group than in the control group(P<0.05). The incidence of gastric retention, abdominal distension and vomiting in the intervention group was lower than that in the control group, but only the difference in the incidence of gastric retention (24.4% vs 47.5%) was statistically significant (P<0.05). The incidence of feeding intolerance was significantly lower in the intervention group than in the control group (24.39% vs 47.50%, P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Comprehensive nursing intervention can shorten the tube feeding time of premature infants, promote the weight growth of premature infants, improve the feeding quality, reduce the incidence of feeding intolerance, and reduce the hospital stay of premature infants, so as to reduce the hospitalization cost, improve the quality of life of premature infants, and increase the satisfaction of parents. \u0000 \u0000 \u0000Key words: \u0000Comprehensive nursing intervention; Premature infant; Feeding intolerance","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43742562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of micronutrients supplementation on plasma homocysteine level and global cognitive function among older adults in long-term care facilities: a randomized controlled study","authors":"Min Zhao, Zhuo Li, Zhuming Jiang, W. Kang, Kang Yu, Q. Lu, Xiaoxi Li, Xianna Zhang, Hai Fang, Yang Wang, Wei Li, Shenggao Han, R. Jing, Zhenshu Li, Dali Sun, Bin Zhao","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.001","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.001","url":null,"abstract":"Objective \u0000To investigate the effects of micronutrient supplementation for the elderly on plasma homocysteine level and cognitive function in institutional older adults. \u0000 \u0000 \u0000Methods \u0000A total of 98 older adults with the score≤11 by mini nutritional assessment short-form aged 65-100 years were enrolled and assigned to either intervention group or control group (n=49 each), with either a package of micronutrient pack or placebo daily, for three months. Fasting blood samples were collected both at baseline and the end of study to detect serum vitamin B12, folate and plasma homocysteine (Hcy) concentrations. Global cognitive function was assessed using the mini-mental state examination (MMSE). The paired t test was used to compare the continuous variables between the two groups after intervention. The relationship between changes in MMSE score and changes in plasma Hcy concentrations was examined by least-squares linear regression. \u0000 \u0000 \u0000Results \u0000Eighty-two patients completed the study, and 17 patients withdrew from the study due to diarrhea and hospital discharge with the drop rate of 17.3%. Compared to the control group, concentrations of serum vitamin B12 (128.8±34.8 vs 13.3±16.0 pmol/L, P=0.003) and folate (21.1±1.6 vs 0.6±0.5 nmol/L, P<0.01) significantly increased in the intervention group over 3-month supplementation, while plasma Hcy levels were remarkably reduced (-5.3±0.7 vs 1.7±0.3 μmol/L, P<0.01). The incidences of deficiency of folate, deficiency of serum vitamin B12and high Hcy all decreased in intervention group. Although individual item scores in MMSE were not changed markedly, change of total MMSE score in intervention group were higher than that in the control group (1.2±3.0 vs -0.2±2.5, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000The supplementation of the micronutrient pack in long-term care facilities can reduce the incidence of hyperhomocysteinemia, and improve the total MMSE score. \u0000 \u0000 \u0000Key words: \u0000Micronutrient; Older adults; Homocysteine; Cognitive function","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48651772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative weight loss and its influencing factors in patients with colorectal cancer","authors":"Yaqin Chu, Jian Zhao, Zhiwei Jiang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.006","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.006","url":null,"abstract":"Objective \u0000To investigate the perioperative weight loss and its influencing factors in patients with colorectal cancer, and to provide evidence for the development and management of perioperative nutritional support strategies. \u0000 \u0000 \u0000Methods \u0000Ninety-one patients with colorectal cancer were enrolled and divided into observation group (n=61) with the degree of weight loss less than 5% of preoperative weight and control group (n=30) with the degree of weight loss more than 5% of preoperative weight. Change of body composition and factors of weight loss in patients with colorectal cancer were compared between the two groups by single factor and multivariate analysis. \u0000 \u0000 \u0000Results \u0000Ninety-one patients with colorectal cancer had the average weight loss of 2.0 kg. Of perioperative changes in body composition, the degree of body fat, muscle mass and protein group decreased statistically (P<0.05). Univariate analysis showed that the age, intraoperative blood loss and postoperative oral nutrition intake compliance were the risk factors for the degree of weight loss in patients with colorectal cancer after the operation. Multivariate logistic regression analysis showed that the intraoperative blood loss was an independent influencing factor for the degree of postoperative weight loss in patients with colorectal cancer (P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Age, intraoperative blood loss and postoperative oral nutritional intake compliance may affect the degree of weight loss during perioperative period. Intraoperative blood loss is an independent risk factor affecting the degree of weight loss during perioperative period. In future clinical research and practice, minimally invasive and accurate surgical treatment should be strengthened, the amount of intraoperative blood loss and surgical trauma should be reduced, and the postoperative oral nutrition intake of patients should be paid attention, especially for elderly patients. Personalized dietary guidance and management for different groups should be conducted, and perioperative nutritional status of patients should be improved. \u0000 \u0000 \u0000Key words: \u0000Colorectal cancer; Weight loss; Body composition; Enhanced recovery after surgery","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46988119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corresponding Application of quality control circle in reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy","authors":"Q. Mou, Hongjuan Li, Li Linjuan","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.003","url":null,"abstract":"Objective \u0000To explore the effect of quality control circle(QCC)on reducing the incidence of moderate or severe malnutrition in gastric cancer patients under chemotherapy. \u0000 \u0000 \u0000Methods \u0000Before the activity (February to March 2016), 146 gastric cancer patients under chemotherapy were selected as the control group, and regular nutrition nursing (dietary guidance and regular nutrition-related health lectures) was given. After the activity (February to March 2017), 139 gastric cancer patients under chemotherapy were selected as QCC group, and the standard intervention of quality control circle was implemented. The nutritional status of patients before and after improvement was compared. \u0000 \u0000 \u0000Results \u0000After finding the cause and formulating and implementing the measures, the 24-hour consultation rate, the incomplete remission rate of nausea/vomiting, the incidence of cancer anorexia, and the rate of missed visits in QCC group were significantly different with those in control group (P<0.05). The incidence of moderate or severe malnutrition was 16.55% in QCC group and 65.07% in control group, and the difference was statistically significant (P<0.01). \u0000 \u0000 \u0000Conclusions \u0000The quality control circle activity can effectively reduce the incidence of moderate or severe malnutrition and improve the quality of life in gastric cancer patients under chemotherapy. It can also improve the self-discipline and initiative of medical staff and improve the quality of medical care. \u0000 \u0000 \u0000Key words: \u0000Quality control circle; Gastric cancer; Chemotherapy; Moderate or severe malnutrition","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43789624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practice of linear quality control on manually compounded total nutrient admixtures","authors":"Zhang Jianzhong, Lao Donghui, Yao Bangxin, Jiang-hua Yi, Yang Chun, Wu Guohao, Lv Qianzhou","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.010","url":null,"abstract":"Objective \u0000To establish a quality control model ensuring good stability and compatibility of manually compounded total nutrient admixtures (TNA). \u0000 \u0000 \u0000Methods \u0000A parenteral nutrition medication order entry system was establish for standardizing nutritional medication usage and supporting physician's TNA prescribing. TNA medication orders were reviewed by pharmacists for validating the stability and compatibility. TNAs were compounded by pharmacists in a standard way following \"four factors of sterile compounding\" . The goal of quality control was achieved by establishment of the preliminary standard. \u0000 \u0000 \u0000Results \u0000The quality of manually compounded total nutrient admixtures achieved the goal since pharmacy intravenous admixture service (PIVAS) started on 2003. \u0000 \u0000 \u0000Conclusions \u0000The quality of TNA is well assured while manually compounded by pharmacists in PIVAS. \u0000 \u0000 \u0000Key words: \u0000Total nutrient admixtures; Pharmacist; Pharmacy intravenous admixture service","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49277515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of oral nutritional supplements on body weight and life qualityin post-discharge patients with gastricor colorectal cancer: A prospective randomized controlled clinical trial","authors":"Yi Jiang, Q. Meng, Shanjun Tan, Qi Zhang, Zhen Yu, Xinping Zhang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.002","url":null,"abstract":"Objective \u0000To investigate the effect of oral nutritional supplements(ONS) on body weight loss and life quality in post-discharge patients with gastric and colorectal cancer. \u0000 \u0000 \u0000Methods \u0000All the enrolled post-operative gastric or colorectal cancer patients were randomly divided into ONS group and control group. Body weight loss, middle arm circumference, triceps skinfold thickness and right-hand grip strength were measured and the Karnofsky score, ECOG score and QOL score were calculated 3 months after the discharge. \u0000 \u0000 \u0000Results \u0000The body weight loss of gastric cancer patients was lower in ONS group than in control group since 2 months after discharge.(2 months after discharge: 1.65±2.11vs. 2.70±1.90 kg, t=-2.385 3, P=0.019 3; 3 months after discharge: 1.95±2.75vs. 3.67±2.29 kg, t=-3.134 7, P=0.002 4), There was no difference of body weight loss between two groups in colorectal cancer patients. The middle arm circumference, triceps skinfold thicknessand right-hand grip strength showed no statistic difference between two groups both in gastric and colorectal cancer patients. The Karnofsky score(56.82±13.65%vs. 51.71±9.72%, t=2.014 8, P=0.047 2) and QOL score(41.91±6.92 vs. 38.39±8.77, t=2.059 7, P=0.042 6) were higher in ONS group than in control group in gastric cancer patients. While all 3 types of scores had no difference between two groups in colorectal cancer patients. \u0000 \u0000 \u0000Conclusion \u0000ONS can efficiently reduce the body weight loss and improve the performance status and life qualityin post-discharge gastric cancer patients, but not in colorectal cancer patients. \u0000 \u0000 \u0000Key words: \u0000Oral nutritional supplement; Gastric malignancy; Colorectal malignancy","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41746270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease","authors":"Caiyun Liu, Hongdi Du, Wei Li, Xiaoxuan Liu","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.05.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.05.005","url":null,"abstract":"Objective \u0000To explore the effect of nutritional support based on clinical nursing pathway on nutritional status and quality of life among elderly inpatients with Alzheimer disease (AD). \u0000 \u0000 \u0000Methods \u0000A total of 101 elderly inpatients with AD who met the criteria of the protocol were consecutively enrolled and randomly divided to study group receiving nutritional support based on clinical nursing pathway for two months (n=51) and control group receiving routine nutritional management for 2 months (n=50). Nutritional risk and quality of life were measured by nutritional risk screening 2002 (NRS 2002) and Quality of Life-Alzheimer's Disease Scale (QOL-AD) respectively before and after nutritional support. \u0000 \u0000 \u0000Results \u0000Baseline data were comparable between the two groups (all P>0.05). After 2-month nutritional support, compared to the control, the incidence of nutritional risk (36.0% vs 17.6%, P=0.037) and undernutrition (26.0% vs 9.8%, P=0.033) decreased significantly in study group. The score of quality of life in study group were significant higher than that of control group (35.73±5.85 vs 30.76±6.14, P=0.023). \u0000 \u0000 \u0000Conclusion \u0000The nutritional support based on clinical nursing pathway is helpful to improve the nutritional status and quality of life in elderly hospitalized patients with AD. \u0000 \u0000 \u0000Key words: \u0000Alzheimer disease; Elderly inpatients; Clinical nursing pathway; Nutritional support; Nutritional risk screening; Quality of life","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49509695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of sarcopenia on the risks of osteoporosis and fragility fractures among community-dwelling middle and old age people: a systematic review and meta-analysis","authors":"Min Cui, Kang Yu, Chun-wei Li, Fang Wang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.04.002","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.04.002","url":null,"abstract":"Objective \u0000To explore the relationship between sarcopenia and the risks of osteoporosis and fragility fractures among community-dwelling middle and old people (≥50 years). \u0000 \u0000 \u0000Methods \u0000OVID/Medline, Pubmed, EMBASE, Cochrane Library, Web of Science (SCI), China National Knowledge Infrastructure (CNKI), and Chinese WanFang Database were searched systematically for literatures related to the relationship between sarcopenia and osteoporosis and fragility fractures from January 1987 to July 2018. The searched literatures were screened based on the inclusion and exclusion criteria. The quality of the literatures were evaluated by using the risk assessment tool NOS (Newcastle-Ottawa Scale) and AHRQ (Agency for Healthcare Research and Quality). Meta-regression analysis was used to explore the cause of heterogeneity between studies. The subgroup analysis was used to assess the differences in the risk of osteoporosis based on the important characteristic variables, such as gender, ethnicity, age, diagnostic criteria of sarcopenia, and outcome type. Sensitivity analysis and trim and fill method were conducted to test the stability of the results of this Meta-analysis. Data collected and summarized by Stata 12.2 software. \u0000 \u0000 \u0000Results \u0000A total of 23 studies in line with quality requirements were included eventually, including 56, 544 subjects. The results of this Meta-analysis were relatively robust. Compared with non-sarcopenia, the relative risk (RR) for osteoporosis among subjects with sarcopenia was 1.61 (95% CI: 1.42~1.82, P<0.000 01). Especially, compared with postmenopausal women RR=1.37 (95% CI: 1.23-1.53, P<0.000 1) and yellow race RR=1.53 (95% CI: 1.34-1.75, P<0.000 1), sarcopenia had a higher impact trend on the risk of osteoporosis in older men RR=2.26 (95% CI: 1.71-2.98, P<0.000 1) and Caucasian RR=2.03 (95% CI: 1.46-2.81, P<0.000 1). \u0000 \u0000 \u0000Conclusion \u0000Among community-dwelling middle and old aged people(≥50 year), sarcopenia increases the risk of osteoporosis and fragility fracture by 61% and 59% -61% significantly, respectively. Middle and old aged people should be prevented and screened early for sarcopenia, which attributes to identify high risk groups of fragile fractures and reduce the risk of adverse outcomes. \u0000 \u0000 \u0000Key words: \u0000Sarcopenia; Osteoporosis; Fragility fractures; Meta-analysis","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42850756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study of the respiratory indirect calorimetry and HB coefficient method for the guidance of the target energy in patients with sepsis","authors":"Xiaojuan Yang, Jun Zhang, Lijuan Wang","doi":"10.3760/CMA.J.ISSN.1674-635X.2019.04.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.1674-635X.2019.04.007","url":null,"abstract":"Objective \u0000To explore the effects of nutritional supports following target energy measured by respiratory indirect calorimetry and HB coefficient method respectively on the nutrition and immune indexes of patients with sepsis. \u0000 \u0000 \u0000Methods \u0000A prospective comparative study of 60 patients with sepsis who was suitable for nutritional support and respiratory indirect calorimetry in the intensive care unit (ICU) of the hospital from January 2015 to October 2015 was conducted. Resting Energy Expenditure (REE) was measured simultaneously by respiratory indirect calorimetry (n=30) and HB coefficient (Harris-Benedict formula×stress coefficient, n=30) in patients with sepsis and the nutritional support was given according to the MREE measured by the two methods. The nutritional and immune indexes were obtained at 0 day, 3 day, 7 day, and 14 day after nutritional support. The nutritional and immune indexes at 0 day were considered as the baseline and the differences in the nutritional and immune indexes between the baseline and 3 day, 7 day and 14 day were expressed as a \"Δ\". Values of Δ were compared between the two goups. \u0000 \u0000 \u0000Results \u0000With nutritional support for 3 days, Δalbumin, Δ prealbumin, Δthe total T lymphocytes, Δassist/induction of T cells and ΔIgG were higher in the respiratory indirect calorimetry group than in the HB coefficient group (P<0.05). With nutritional support for 7 days, Δalbumin, ΔT lymphocytes, ΔIgM were higher in the respiratory indirect calorimetry group than in the HB coefficient group (P<0.05). With nutritional support for 14 days, Δtransferrin, Δsuppression/cytotoxic T cells, ΔIgG, ΔIgA, ΔC3 andΔC4 were higher in the respiratory indirect calorimetry group than in the HB coefficient group(P<0.05). \u0000 \u0000 \u0000Conclusion \u0000Nutritional support with REE measured by respiratory indirect calorimetry in patients with sepsis is more effective on nutritional and immune related indexes improvement have different degrees of improvement, thus respiratory indirect calorimetry is more suitable to guide the target energy of sepsis patients. \u0000 \u0000 \u0000Key words: \u0000Sepsis; Target energy; Respiratory indirect calorimetry; HB coefficient; Nutrition","PeriodicalId":9877,"journal":{"name":"Chinese Journal of Clinical Nutrition","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42818382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}