Archives of Gerontology and Geriatrics Plus最新文献

英文中文

What is the burden of neurological disorders associated to population aging in Brazil? ecological temporal-trend study 在巴西，与人口老龄化相关的神经系统疾病的负担是什么？生态时间趋势研究

Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-14 DOI: 10.1016/j.aggp.2026.100249

Natan Feter , Marcos Cirilo Sana Monteiro , Leticia Vitória Mourão Meira Pereira , Eduarda da Cunha Policarpo , Samuel Carvalho Dumith

Objectives

Population aging in Brazil has led to a significant increase in the burden of neurological disorders. This study aimed to examine the association of demographic aging with this burden.

Study design

An ecological temporal-trend study.

Methods

This time-series ecological study analyzed neurological disorder burden and population aging across 27 Brazilian states (1991–2023). Data from the Global Burden of Disease (IHME) and Brazilian Institute of Geography and Statistics (IBGE) were used. We calculated annual percentage changes (APCs) for five neurological indicators and population aging. Prais-Winsten regression analyzed aging trends, and linear regression assessed its association with neurological disorders, adjusting for covariates.

Results

The proportion of older adults (≥60 years) in Brazil more than doubled from 6.6% in 1991 to 14.2% in 2022. Concomitantly, all indicators of neurological disorders, including mortality (a 34.6% increase) and disability-adjusted life years (DALYs, a 20.5% increase), exhibited upward trends. Our findings reveal that aging is an independent predictor of worsening health indicators; each one-percentage-point increase in the elderly population was associated with a 2.9% rise in mortality and a 1.8% increase in DALYs.

Conclusion

Population aging is a significant and independent indicator of worsening neurological health in Brazil, posing critical public health challenges that require coordinated action. It is essential to strengthen the Unified Health System (SUS) to address the demand for specialized neurological care.

巴西人口老龄化导致神经系统疾病负担显著增加。本研究旨在探讨人口老龄化与这种负担的关系。研究设计：生态时间趋势研究。方法对1991-2023年巴西27个州的神经系统疾病负担和人口老龄化进行时序生态学研究。数据来自全球疾病负担（IHME）和巴西地理与统计研究所（IBGE）。我们计算了五项神经学指标与人口老龄化的年百分比变化（APCs）。Prais-Winsten回归分析了衰老趋势，线性回归评估了其与神经系统疾病的关系，调整了协变量。结果巴西老年人（≥60岁）的比例从1991年的6.6%增加到2022年的14.2%，增长了一倍多。与此同时，神经系统疾病的所有指标，包括死亡率（增加34.6%）和残疾调整生命年（DALYs，增加20.5%），均呈现上升趋势。我们的研究结果表明，年龄是健康指标恶化的独立预测因子；老年人口每增加一个百分点，死亡率就会增加2.9%，伤残调整生命年增加1.8%。结论人口老龄化是巴西神经系统健康恶化的一个重要而独立的指标，构成了需要协调行动的重大公共卫生挑战。必须加强统一卫生系统（SUS），以满足对神经专科护理的需求。

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引用次数: 0

Association between chronic lung disease and chronic heart disease among middle-aged and older adults in India: A gender-stratified cross-sectional analysis 印度中老年人慢性肺病和慢性心脏病之间的关系：一项性别分层的横断面分析

Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-11 DOI: 10.1016/j.aggp.2026.100245

Hemant Singh Gurjar , Gaurav Sharma , Anjna Kumari

Background

Chronic heart disease (CHD) and chronic lung disease (CLD) are major contributors to morbidity and mortality among ageing populations, often sharing common risk factors and biological pathways. Despite evidence of cardiopulmonary interactions, few studies in India have examined gender differences and effect modification in the association between CLD and CHD using nationally representative data. This study estimates the prevalence of CLD and CHD among Indian adults aged ≥45 years, examines their association, and explores gender differences in the distribution and contribution of BMI, self-rated health, hypertension, diabetes, cancer, stroke, and high cholesterol within this association.

Data and Methods

We analysed cross-sectional data from 60,632 respondents in Wave 1 of the LASI (2017–2018). Weighted descriptive statistics and multivariable logistic regression models assessed associations between CLD and CHD, incorporating interaction terms for key health risk factors. Mediation analysis used the Karlson–Holm–Breen method to decompose total effects into direct and indirect effects.

Results

The prevalence of CHD and CLD was 3.86% and 7.29%, respectively. Females with CLD had higher odds of CHD (AOR=2.89) than males. Significant interaction effect modifications were observed for SRH, hypertension, high BMI, diabetes, cancer, stroke, and high cholesterol, predominantly among females. Mediation decomposition analysis identified SRH as the strongest mediator, explaining 34% of the observed CLD–CHD association overall (52% in males, 24% in females), followed by hypertension (10%) and high cholesterol (5%).

Conclusion

CLD and CHD are more prevalent among middle-aged and older adults in India, with co-occurrence influenced by age, multimorbidity, obesity, poor SRH and cardiometabolic conditions. Gender differences and geographic variation underscore the need for tailored strategies. Recognising CLD–CHD coexistence can inform comprehensive geriatric assessment, risk stratification and coordinated care, while population-level interventions should integrate lifestyle promotion, multimorbidity management and gender-sensitive approaches.

背景：慢性心脏病（CHD）和慢性肺部疾病（CLD）是老年人群发病率和死亡率的主要原因，通常具有共同的危险因素和生物学途径。尽管存在心肺相互作用的证据，但在印度很少有研究使用具有全国代表性的数据来检查CLD和冠心病之间关联的性别差异和效果改变。本研究估计了年龄≥45岁的印度成年人中CLD和冠心病的患病率，研究了它们之间的相关性，并探讨了BMI、自评健康、高血压、糖尿病、癌症、中风和高胆固醇在这一相关性中的分布和贡献的性别差异。数据和方法我们分析了LASI第一波（2017-2018）60,632名受访者的横截面数据。加权描述性统计和多变量逻辑回归模型评估了CLD和冠心病之间的关联，纳入了关键健康风险因素的相互作用项。中介分析采用Karlson-Holm-Breen方法将总效应分解为直接效应和间接效应。结果冠心病和CLD患病率分别为3.86%和7.29%。CLD女性发生冠心病的几率高于男性（AOR=2.89）。在SRH、高血压、高BMI、糖尿病、癌症、中风和高胆固醇中观察到显著的相互作用改变，主要发生在女性中。中介分解分析发现SRH是最强的中介，解释了观察到的CLD-CHD相关的34%（男性52%，女性24%），其次是高血压（10%）和高胆固醇（5%）。结论cld和CHD在印度中老年人群中较为常见，并受年龄、多发病、肥胖、不良SRH和心脏代谢状况的影响。性别差异和地域差异突出表明需要有针对性的战略。认识到慢性阻塞性肺病和冠心病共存可以为全面的老年评估、风险分层和协调护理提供信息，而人群层面的干预措施应结合生活方式促进、多病管理和性别敏感方法。

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引用次数: 0

Kinematic analysis of one-leg standing for locomotive syndrome screening using marker-less motion capture and machine learning: A cross-sectional study 使用无标记运动捕捉和机器学习进行机车综合征筛查的单腿站立运动学分析：一项横断面研究

Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-03 DOI: 10.1016/j.aggp.2026.100244

Kazuaki Hamada B.S. , Yu Inoue Ph.D. , Shigeharu Tanaka Ph.D. , Hungu Jung Ph.D. , Kenta Hirohama M.S. , Ryo Yamasaki B.S. , Koji Ono Ph.D. , Ryo Tanaka Ph.D.

Objectives

Locomotive syndrome (LS), caused by musculoskeletal dysfunction, is a major concern for older adults, contributing to physical decline, increased caregiving needs, and loss of autonomy. This study aimed to develop a novel LS screening method by analyzing kinematic data from the one-leg standing (OLS) test using a marker-less motion capture system combined with machine learning.

Methods

A total of 294 community-dwelling older adults participated, and LS severity was evaluated using the LS risk test. Kinematic data were collected during the OLS test by marker-less motion capture system and analyzed with neural network models to classify LS severity into stage 1 or higher and stage 2 or higher.

Results

The proposed model demonstrated superior classification accuracy compared to conventional OLS time-based assessments, with area under the curve (AUC) values of 0.901 for stage 1 or higher and 0.904 for stage 2 or higher, exceeding the performance reported in previous studies.

Conclusions

This study demonstrates the feasibility of integrating kinematic analysis with machine learning to screen LS. The developed model offers a noninvasive and efficient tool for LS detection, suitable for both telemedicine and community-based applications. By facilitating early detection of LS, this approach has the potential to improve enhance clinical outcomes and reduce caregiving burdens.

机车综合征（LS）是由肌肉骨骼功能障碍引起的，是老年人主要关注的问题，会导致身体衰退、护理需求增加和自主性丧失。本研究旨在开发一种新的LS筛选方法，通过使用无标记运动捕捉系统结合机器学习分析单腿站立（OLS）测试的运动学数据。方法采用LS风险测试对294例社区老年人进行LS严重程度评价。通过无标记运动捕捉系统收集OLS测试过程中的运动学数据，并使用神经网络模型进行分析，将LS严重程度分为1级及以上和2级及以上。结果与传统的OLS时间评价相比，该模型的分类精度更高，第一阶段及以上的曲线下面积（AUC）为0.901，第二阶段及以上的AUC为0.904，超过了以往研究报告的性能。结论本研究证明了将运动学分析与机器学习相结合来筛选LS的可行性。所开发的模型为LS检测提供了一种无创、高效的工具，适用于远程医疗和社区应用。通过促进LS的早期发现，这种方法有可能改善临床结果并减轻护理负担。

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引用次数: 0

Evaluating the two-minute walk test as a time-efficient alternative to the six-minute walk test in Nigerian older adults: Insights from an exploratory mediation and moderation analysis 评估两分钟步行测试作为时间效率替代六分钟步行测试在尼日利亚老年人：来自探索性调解和适度分析的见解

Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-03 DOI: 10.1016/j.aggp.2026.100243

Michael E. Kalu , Ajayi K. Oladimeji , Israel Adandom , Nusrat S. Nessa , Chigozie L.J. Ugwu , Chukwuebuka P. Onyekere , Francis O. Kolawole , Henrietta Fawole

Purpose

This study aimed to test whether the 2-Minute Walk Test (2MWT) can substitute for the 6-Minute Walk Test (6MWT) when estimating functional capacity in Nigerian older adults and to identify physiological mediators or moderators of that relationship.

Methods

We conducted a cross-sectional study and recruited 409 adults ≥ 60 years who completed both walk tests; gait speed was the primary outcome. Age, sex, body-mass index (BMI), Montreal Cognitive Assessment scores, and estimated VO₂ max were also recorded.

Results

This study indicated that 2MWT gait speed strongly predicted 6MWT gait speed (β = 0.547, p < 0.001), accounting for 35 % of its variance. Age, cognition, BMI, and VO₂ max did not mediate this association, but VO₂ max moderated it (interaction β = 0.0175, p < 0.05). Bland–Altman analysis showed a small systematic underestimation by the 2MWT, with acceptable agreement when mean speeds were 0.7–1.2 m s⁻¹.

Conclusion

We concluded that the 2MWT could offer a time-efficient proxy for the 6MWT in low-resource settings, although clinicians should interpret results cautiously in individuals with low aerobic fitness.

目的本研究旨在测试2分钟步行测试（2MWT）是否可以替代6分钟步行测试（6MWT）来估计尼日利亚老年人的功能能力，并确定这种关系的生理介质或调节因子。方法：我们进行了一项横断面研究，招募了409名≥60岁的成年人，他们完成了两项步行测试；步态速度是主要观察指标。此外，还记录了年龄、性别、身体质量指数（BMI）、蒙特利尔认知能力评价分数、VO₂max预测值等。结果本研究表明，2MWT步态速度对6MWT步态速度有较强的预测作用（β = 0.547, p < 0.001），占方差的35%。年龄、认知、BMI和vo2 max没有介导这种关联，但vo2 max调节了这种关联（交互作用β = 0.0175, p < 0.05）。Bland-Altman分析显示2MWT有一个小的系统性低估，当平均速度为0.7-1.2 m s时，结果是可以接受的。我们的结论是，在低资源环境下，2MWT可以作为6MWT的时间效率代表，尽管临床医生在低有氧适应度的个体中应谨慎解释结果。

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引用次数: 0

Postural instability in the digital age: A scoping review of screen exposure and balance outcomes in community-dwelling older adults 数字时代的姿势不稳定：对社区居住的老年人的屏幕暴露和平衡结果的范围审查

Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-02 DOI: 10.1016/j.aggp.2025.100242

Tamanna Sharma BPT, (MPT) , Nidhi Sharma BPT, MPT, PhD , Simranjeet Kaur BPT, MPT , Parveen Kumar BPT, MPT , Preeti Kapri BPT, MPT

Background

Digital screen use is increasingly common among older adults, yet its implications for balance and postural control are not well defined. Age-related sensory, vestibular and cognitive changes may increase vulnerability to balance disturbances during screen-based activities.

Objective

To map and describe how screen exposure has been explored in relation to balance-related outcomes in community-dwelling adults aged 60 years and older.

Methods

A scoping review was conducted following Joanna Briggs Institute guidance and the PRISMA-ScR framework. Systematic searches of eight electronic databases identified studies published in English between December 2000 and June 2024. Observational and experimental studies assessing any form of digital screen exposure in relation to balance, gait, vestibulo-ocular function, or dizziness in adults aged ≥60 years were eligible. Data were charted descriptively to map exposure types, balance domains, measurement tools, and methodological characteristics.

Results

Five studies met the inclusion criteria. Screen exposures included total daily screen time, smartphone use during walking, sustained near-focus visual tasks, and immersive or visually provocative digital environments. Balance-related outcomes encompassed postural sway, gait parameters, dynamic visual acuity, vestibulo-ocular reflex function, and self-reported dizziness. Substantial heterogeneity was observed across exposure definitions, measurement tools, and study designs. Most evidence was cross-sectional or based on short-duration experimental protocols.

Conclusion

Evidence examining screen exposure and balance in older adults is limited and methodologically diverse. This scoping review provides a structured mapping of the existing literature rather than an assessment of effects or causality, highlighting gaps to inform future research on digital behaviour and balance in ageing populations.

数字屏幕的使用在老年人中越来越普遍，但其对平衡和姿势控制的影响尚未得到很好的定义。与年龄相关的感觉、前庭和认知变化可能会增加屏幕活动中平衡性障碍的易感性。目的绘制并描述如何探索屏幕暴露与60岁及以上社区居住成年人平衡相关结果的关系。方法根据Joanna Briggs研究所的指导和PRISMA-ScR框架进行范围审查。对8个电子数据库进行系统搜索，确定了2000年12月至2024年6月期间用英语发表的研究。在年龄≥60岁的成年人中，评估任何形式的数字屏幕暴露与平衡、步态、前庭-眼功能或头晕相关的观察性和实验性研究均符合条件。将数据绘制成描述性图表，以绘制暴露类型、平衡域、测量工具和方法特征。结果5项研究符合纳入标准。屏幕暴露包括每天总屏幕时间、走路时使用智能手机、持续的近焦视觉任务、沉浸式或视觉刺激的数字环境。平衡相关的结果包括姿势摇摆、步态参数、动态视力、前庭-眼反射功能和自我报告的头晕。在暴露定义、测量工具和研究设计中观察到大量异质性。大多数证据是横断面的或基于短时间的实验方案。结论：检查老年人屏幕暴露和平衡的证据有限，方法多样。这一范围审查提供了现有文献的结构化映射，而不是对影响或因果关系的评估，突出了差距，为未来关于老龄化人口的数字行为和平衡的研究提供了信息。

{"title":"Postural instability in the digital age: A scoping review of screen exposure and balance outcomes in community-dwelling older adults","authors":"Tamanna Sharma BPT, (MPT) , Nidhi Sharma BPT, MPT, PhD , Simranjeet Kaur BPT, MPT , Parveen Kumar BPT, MPT , Preeti Kapri BPT, MPT","doi":"10.1016/j.aggp.2025.100242","DOIUrl":"10.1016/j.aggp.2025.100242","url":null,"abstract":"<div><h3>Background</h3><div>Digital screen use is increasingly common among older adults, yet its implications for balance and postural control are not well defined. Age-related sensory, vestibular and cognitive changes may increase vulnerability to balance disturbances during screen-based activities.</div></div><div><h3>Objective</h3><div>To map and describe how screen exposure has been explored in relation to balance-related outcomes in community-dwelling adults aged 60 years and older.</div></div><div><h3>Methods</h3><div>A scoping review was conducted following Joanna Briggs Institute guidance and the PRISMA-ScR framework. Systematic searches of eight electronic databases identified studies published in English between December 2000 and June 2024. Observational and experimental studies assessing any form of digital screen exposure in relation to balance, gait, vestibulo-ocular function, or dizziness in adults aged ≥60 years were eligible. Data were charted descriptively to map exposure types, balance domains, measurement tools, and methodological characteristics.</div></div><div><h3>Results</h3><div>Five studies met the inclusion criteria. Screen exposures included total daily screen time, smartphone use during walking, sustained near-focus visual tasks, and immersive or visually provocative digital environments. Balance-related outcomes encompassed postural sway, gait parameters, dynamic visual acuity, vestibulo-ocular reflex function, and self-reported dizziness. Substantial heterogeneity was observed across exposure definitions, measurement tools, and study designs. Most evidence was cross-sectional or based on short-duration experimental protocols.</div></div><div><h3>Conclusion</h3><div>Evidence examining screen exposure and balance in older adults is limited and methodologically diverse. This scoping review provides a structured mapping of the existing literature rather than an assessment of effects or causality, highlighting gaps to inform future research on digital behaviour and balance in ageing populations.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100242"},"PeriodicalIF":0.0,"publicationDate":"2026-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145925283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-01

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Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-01

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Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-01

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Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-01

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Archives of Gerontology and Geriatrics Plus

Pub Date : 2026-01-01

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