The aging population of the world is increasing. Aging leads to risks for frailty and other chronic diseases and health systems must focus more on prevention to guarantee healthy aging. The primary objective was to estimate the efficacy of the POSITIVE-(The Maintaining and imPrOving the intrinSIc capaciTy Involving Primary Care and caregiVErs) system in improving frailty during a 6-month follow-up period.
A randomized controlled, assessor-blinded pilot study (RCT) with 50 individual < 70 years, pre-frail or frail was recruited from a primary care center in Stockholm Region. All participants received a drug review, nutritional recommendations, and a Vivifrail physical exercise program. In addition, the intervention group received POSITIVE including a tablet, an application, and portable measurement devices. The intervention group was monitored remotely by a primary care nurse at the primary health care centre during a six-month follow-up period.
At baseline there was a significance between the groups regarding the FTS-5 scale, and significantly more obese participants in the intervention group. The drug reviews showed that three of 43 participants got a review and new diseases were discovered. The test of interactions showed a tendency for significant differences over time between the groups in frailty measured by Fried Frailty Phenotype's and FTS-5 scales.
Frailty status over time in the intervention group not differed significantly from the controls. Including individuals to the project even through a pandemic showing that the design is possible for future studies to show effects of new ways of preventing frailty at home.
ClinicalTrials.gov. Registration number: NCT04592146. October 19, 2020. https://clinicaltrials.gov/ct2/show/NCT04592146?term=positive&draw=2&rank=7
We aim to evaluate trends in Cerebrovascular Diseases (CVD) and pelvic and hip fractures (PHF)-related deaths among adults (≥ 65 years) in the US from 1999 to 2020, highlighting the differences based on demographics.
We analyzed death certificates from the CDC WONDER (Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research) database spanning 1999 to 2020, related to CVD and PHF in people aged ≥65 years. Age-Adjusted Mortality Rates (AAMRs) per 100,000 persons and annual percent change (APC) were computed using Joinpoint software. The analysis was organized by year, sex, race/ethnicity, and geographic distribution (states, census regions, metropolitan/non-metropolitan areas).
The AAMR for CVD and PHF decreased from 4.5 in 1999 to 2.2 in 2020. Similar pattern was observed for AAMR in females and males. Highest overall AAMR was noted in Non-Hispanic (NH) White adults (3.2) and lowest in African Americans (1.2). States of Wyoming, Alaska, North Dakota, Oregon, and Minnesota were in the top 90th percentile of AAMR while Florida, District of Columbia, Nevada, Arizona, and New York were in lower 10th percentile. Highest AAMRs were observed in Midwestern census region, followed by Western, Southern and Northeastern regions (3.8,2.8,2.7, and 1.9 respectively). Nonmetropolitan areas had a higher AAMR (4.4 vs 2.5) than metropolitan areas.
The CVDs and PHF related mortality rate increased steadily after 2014. NH white females were found to be at increased risk. A research-based management plan needs to be devised for post stroke pelvic and hip fractures in elderly.
The objective of this study was to identify shifts in older adults’ well-being over the first two years of the COVID-19 pandemic. Between March 2020 and April 2022, 76 adults aged 65+ from the upper Midwest participated in telephone interviews across five timepoints. Quantitative and qualitative questions focused on perceptions of QOL, physical health and mental health, as well as changes over the two years of interviews. Repeated measures ANOVAs indicated significant changes in self-reported QOL over time, but no significant changes to self-reported physical or mental health. Thematic content analysis revealed relevant themes for each content area. Findings provided a longitudinal view of changes in perceived QOL and health among older adults during the COVID-19 pandemic. Despite quantitative improvements in QOL and stability in health, qualitative themes indicated nuances impacts including challenges to physical activity and fluctuations in mental health and QOL.
Despite rapid population ageing in Africa, research on frailty in the region remains limited and fragmented. This systematic review aimed at summarising the available data to determine the prevalence of frailty in Africa.
Original research articles that reported the prevalence and associated factors of frailty in older people were included. The PubMed, Web of Science, SCOPUS, CINAHL, Science Direct, African Index Medicus, African Journals Online, WHO Global Health Library, and HINARI databases were searched between July 30 and September 30, 2022. Eleven studies were selected based on predefined eligibility criteria. To ensure methodological quality, the included studies were independently assessed by two authors. Data were extracted using a standardised data extraction checklist. Due to high heterogeneity among the studies, data were systematically examined using a narrative review.
This review included a sample of 4,112 older people from different regions in Africa. Of the 11 included studies, five (45.5%) recruited study participants from community settings whereas two studies were from nursing homes. A variety of frailty measurement instruments were employed across the studies. The prevalence of frailty considerably varies across the studies: ranging from 9.25% to 77.1%. Increasing age, multimorbidity, nutritional problems, depression, and physical inactivity were identified as risk factors for frailty.
The findings revealed a varying degree of frailty among older people in Africa. It is recommended that institutions provide opportunities for physical activity, ensure adequate nutrition, promote social interaction, and manage chronic illnesses to mitigate frailty.
PROSPERO ID of CRD42021272920.
Previously, we have shown that movement path distance and displacement during a 20-sec stepping test (ST) discriminates between independent and dependent-living older adults. The present study aims to determine whether movement and displacement characteristics during ST are an indicator of risk of falling in independent-living, community-dwelling older women
Independent-living older women recruited for this cross-sectional study were divided into a fall (F: n = 154) or no fall (NF: n = 847) history group. Each participant completed one trial of an eyes open, ST. ST outcome measures included head total movement distance (TMD), maximum movement displacement of the head (MMD), total knee movement distance (KMD), maximum height of the left and right knees (MKH), and step number (STEP) as determined with a KINECTTM infrared depth sensor. Ratio of KMD/TMD was calculated to index upper- body sway relative to the lower-body.
Age, height, body mass, and BMI were not different between groups. KMD (F: median: 4.812 m, interquartile range (IQR): 3.720–7.718 m; NF: 5.309 m, 4.266–6.600 m), TMD / KMD (F: 0.145 m, 0.107–0.196 m; NF: 0.127 m, 0.100–0.170 m) and MKH (F: 0.073 m, 0.052–0.106 m, NF: 0.091 m, 0.060–0.135 m) were different between F and NF (Mann-Whitney, P < 0.05). Logistic regression revealed an association between falls and KMD (OR 1.232, 95 % CI 1.108–1.370).
Characteristics of ST movement and displacement assessed with KinectTM provide useful indicators for fall risk assessment among independent-living, community-dwelling older women.
This study aimed to investigate the determinants of decline in activities of daily living (ADL) among people with dementia following the onset of the coronavirus disease of 2019 (COVID-19).
A retrospective analysis was performed, including 37 individuals with dementia residing in group and nursing homes. The study cohort experienced a resurgence in facility admissions following COVID-19 outbreak, spanning from September to December 2022. Multivariate generalized linear mixed-effects models were employed to assess the Barthel Index at the time of readmission, which served as the dependent variable. Demographic variables before contracting COVID-19 were considered independent predictors if they were significantly associated with the Barthel Index at the time of readmission. Random intercepts were applied to account for variations among facilities in which individuals resided before contracting COVID-19.
Care level, degree of independent living for disabled older adults, and the ability to perform daily ambulatory movements were significantly associated with the Barthel Index at the time of readmission. When used as independent variables, both daily ambulatory movement (beta = 0.350) and care level (beta = -0.347) showed significant associations with the Barthel Index at the time of readmission. Whereas using daily ambulatory movements and the degree of independent living for disabled older adults as independent variables, only the degree of independent living for disabled older adults (beta = -0.757) was significantly associated with the Barthel Index at the time of readmission.
The ability to engage in daily ambulatory movement affects the decline in ADLs due to COVID-19.