Pub Date : 2025-12-08DOI: 10.1016/j.aggp.2025.100236
Raghunath Mandi, Dhananjay W Bansod PhD, Amit Kumar Goyal
India experienced considerable changes in social structure and family institutions, which have tremendous implications on the caregiving structure for older adults, especially for those who, due to physical disability, are unable to care for themselves. As India navigates the complexities of an aging population, rethinking family care is crucial to ensuring the well-being and dignity of older adults. Using data from the Longitudinal Ageing Study in India (LASI), this study examined the pattern of family care provisions, with specific to the role of living arrangements, the impact of spousal presence, and children’s proximity on caregiving choices using logistic regression. Findings highlighted only one-fourth of older adults receive care from families. Spouses continued to play a major role in caregiving, even if they were co-residing with children. The presence of extended family members & proximity to children reduces the complete dependence on children for care. Family dynamics in care provision are shaped by various interconnected factors. These factors influence the type, intensity, and emotional appearance of caregiving. Understanding these dynamics is crucial for families and policymakers in addressing the challenges and ensuring that older adults receive the care and support they need.
{"title":"Rethinking family care: How changing family dynamics are reshaping support for older adults in india?","authors":"Raghunath Mandi, Dhananjay W Bansod PhD, Amit Kumar Goyal","doi":"10.1016/j.aggp.2025.100236","DOIUrl":"10.1016/j.aggp.2025.100236","url":null,"abstract":"<div><div>India experienced considerable changes in social structure and family institutions, which have tremendous implications on the caregiving structure for older adults, especially for those who, due to physical disability, are unable to care for themselves. As India navigates the complexities of an aging population, rethinking family care is crucial to ensuring the well-being and dignity of older adults. Using data from the Longitudinal Ageing Study in India (LASI), this study examined the pattern of family care provisions, with specific to the role of living arrangements, the impact of spousal presence, and children’s proximity on caregiving choices using logistic regression. Findings highlighted only one-fourth of older adults receive care from families. Spouses continued to play a major role in caregiving, even if they were co-residing with children. The presence of extended family members & proximity to children reduces the complete dependence on children for care. Family dynamics in care provision are shaped by various interconnected factors. These factors influence the type, intensity, and emotional appearance of caregiving. Understanding these dynamics is crucial for families and policymakers in addressing the challenges and ensuring that older adults receive the care and support they need.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100236"},"PeriodicalIF":0.0,"publicationDate":"2025-12-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145737649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.aggp.2025.100226
Madhusmita Tipiria M.A. , Ujjwal Das Ph.D.
Background
Hypertension is one of the major causes of premature death and one of the leading risk factors for multi-morbidity. Multi-morbidity with hypertension is more prevalent in older adults as compare to younger people. This study aims to assess the prevalence and risk factors of multi-morbidity among older adults with hypertension in India.
Methods
The study using the data from the Longitudinal Ageing Study in India (LASI) conducted in 2017-18. Multi-nominal regression models were used to examine the association between multi-morbidity and various socio-demographic factors among older adults with hypertension. Additionally, Structural Equation Model was employed to identify the direct effects of exogeneous factors on Multi-morbidity with Hypertension.
Results
The finding represents that the risk of multi-morbidity with hypertension is higher at the age of 75 and above (RRR= 8.23) as compared to young age people. The prevalence of multi-morbidity with hypertension increases with age, economic status, education. Gender difference indicates that females had 39 % lower risk of multimorbidity than males. SEM result shows that among all the exogenous factor age, social group, education and MPCE of the respondent showed the highest direct effect on multi-morbidity with hypertension. The prevalence of multi-morbidity with Hypertension is higher in the state Punjab (41.92 %) and followed by Jammu & Kashmir, and the lower prevalence of multi-morbidity with Hypertension in the state Nagaland (12.57 %).
Conclusion
This research provides valuable insights into the healthcare needs of older adults with hypertension and inform policy interventions for better management of chronic diseases in aging populations.
{"title":"Coexisting morbidities among older adults with hypertension in India: Prevalence and risk analysis","authors":"Madhusmita Tipiria M.A. , Ujjwal Das Ph.D.","doi":"10.1016/j.aggp.2025.100226","DOIUrl":"10.1016/j.aggp.2025.100226","url":null,"abstract":"<div><h3>Background</h3><div>Hypertension is one of the major causes of premature death and one of the leading risk factors for multi-morbidity. Multi-morbidity with hypertension is more prevalent in older adults as compare to younger people. This study aims to assess the prevalence and risk factors of multi-morbidity among older adults with hypertension in India.</div></div><div><h3>Methods</h3><div>The study using the data from the Longitudinal Ageing Study in India (LASI) conducted in 2017-18. Multi-nominal regression models were used to examine the association between multi-morbidity and various socio-demographic factors among older adults with hypertension. Additionally, Structural Equation Model was employed to identify the direct effects of exogeneous factors on Multi-morbidity with Hypertension.</div></div><div><h3>Results</h3><div>The finding represents that the risk of multi-morbidity with hypertension is higher at the age of 75 and above (RRR= 8.23) as compared to young age people. The prevalence of multi-morbidity with hypertension increases with age, economic status, education. Gender difference indicates that females had 39 % lower risk of multimorbidity than males. SEM result shows that among all the exogenous factor age, social group, education and MPCE of the respondent showed the highest direct effect on multi-morbidity with hypertension. The prevalence of multi-morbidity with Hypertension is higher in the state Punjab (41.92 %) and followed by Jammu & Kashmir, and the lower prevalence of multi-morbidity with Hypertension in the state Nagaland (12.57 %).</div></div><div><h3>Conclusion</h3><div>This research provides valuable insights into the healthcare needs of older adults with hypertension and inform policy interventions for better management of chronic diseases in aging populations.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100226"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.aggp.2025.100227
Liang-Kung Chen MD, PhD
{"title":"The AWGS 2025 update: From sarcopenia diagnosis to life-course muscle health promotion","authors":"Liang-Kung Chen MD, PhD","doi":"10.1016/j.aggp.2025.100227","DOIUrl":"10.1016/j.aggp.2025.100227","url":null,"abstract":"","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100227"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.aggp.2025.100231
Neelesh Benet, Vijay Kumar, Srikar Vijayasarthy
Introduction
Mild Cognitive Impairment (MCI) represents an intermediate stage between normal aging and dementia. Emerging evidence suggests that central auditory processing (CAP) deficits may appear even earlier and serve as sensitive indicators of cognitive decline.
Objective
The literature was reviewed to examine the CAP abilities in individuals with MCI. It also examines existing MCI diagnostic guidelines from various countries to assess how CAP assessments are currently integrated in clinical protocols.
Method
A systematic literature search was conducted using PubMed/Medline, Cochrane Library, Scopus and Google Scholar (Jan 2014–Dec 2024). Key search terms included “temporal resolution,” “dichotic,” “speech-in-noise,” “auditory working memory,” “central auditory processing disorder,” “auditory scene analysis,” “temporal gap detection,” “auditory discrimination,” and “mild cognitive impairment.” Only those studies were shortlisted if they investigated CAP in elderly individuals with MCI. Articles outlining MCI diagnostic guidelines were also considered.
Result
Twenty-nine articles met the inclusion criteria. Twenty-three indicated a significant CAP deficit in persons with MCI. Studies consistently show MCI is associated with CAP impairments. Tests like Gap Detection Threshold, Dichotic Digit Test, Sentence-in-Noise, and Digits Backward effectively distinguish MCI patients from healthy controls. Six articles focused on diagnostic guidelines from various countries. Despite many studies showing CAP deficits in MCI, leading diagnostic guidelines do not include CAP tests.
Conclusion
CAP tests hold promise for the early detection of MCI. Integrating them into clinical guidelines can improve diagnostic sensitivity which may delay its progression to Alzheimer’s disease. Despite their diagnostic utility, such tests are not included in the MCI diagnostic frameworks.
{"title":"Auditory-cognitive markers of mild cognitive impairment: Evidence from a systematic review","authors":"Neelesh Benet, Vijay Kumar, Srikar Vijayasarthy","doi":"10.1016/j.aggp.2025.100231","DOIUrl":"10.1016/j.aggp.2025.100231","url":null,"abstract":"<div><h3>Introduction</h3><div>Mild Cognitive Impairment (MCI) represents an intermediate stage between normal aging and dementia. Emerging evidence suggests that central auditory processing (CAP) deficits may appear even earlier and serve as sensitive indicators of cognitive decline.</div></div><div><h3>Objective</h3><div>The literature was reviewed to examine the CAP abilities in individuals with MCI. It also examines existing MCI diagnostic guidelines from various countries to assess how CAP assessments are currently integrated in clinical protocols.</div></div><div><h3>Method</h3><div>A systematic literature search was conducted using PubMed/Medline, Cochrane Library, Scopus and Google Scholar (Jan 2014–Dec 2024). Key search terms included “temporal resolution,” “dichotic,” “speech-in-noise,” “auditory working memory,” <strong>“central auditory processing disorder,” “auditory scene analysis,” “temporal gap detection,” “auditory discrimination,”</strong> and “mild cognitive impairment.” Only those studies were shortlisted if they investigated CAP in elderly individuals with MCI. Articles outlining MCI diagnostic guidelines were also considered.</div></div><div><h3>Result</h3><div>Twenty-nine articles met the inclusion criteria. Twenty-three indicated a significant CAP deficit in persons with MCI. Studies consistently show MCI is associated with CAP impairments. Tests like Gap Detection Threshold, Dichotic Digit Test, Sentence-in-Noise, and Digits Backward effectively distinguish MCI patients from healthy controls. Six articles focused on diagnostic guidelines from various countries. Despite many studies showing CAP deficits in MCI, leading diagnostic guidelines do not include CAP tests.</div></div><div><h3>Conclusion</h3><div>CAP tests hold promise for the early detection of MCI. Integrating them into clinical guidelines can improve diagnostic sensitivity which may delay its progression to Alzheimer’s disease. Despite their diagnostic utility, such tests are not included in the MCI diagnostic frameworks.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100231"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145617839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-12-01DOI: 10.1016/j.aggp.2025.100210
Ayumi Honda , Yin Liu , Mayo Ono , Takahiro Nishida , Tatsuya Tsukigi , Elizabeth B. Fauth , Sumihisa Honda
{"title":"Corrigendum to “Restrictions in community-based care services and the effect on family caregivers during the COVID-19 pandemic: A mixed-methods study” [Archives of Gerontology and Geriatrics Plus, Volume 2, Issue 4 (2025), Article 100205]","authors":"Ayumi Honda , Yin Liu , Mayo Ono , Takahiro Nishida , Tatsuya Tsukigi , Elizabeth B. Fauth , Sumihisa Honda","doi":"10.1016/j.aggp.2025.100210","DOIUrl":"10.1016/j.aggp.2025.100210","url":null,"abstract":"","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100210"},"PeriodicalIF":0.0,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145684223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preventing the deterioration of health of older adults who need preventive care services from the “support level” to the “care level” in the long-term care insurance (LTCI) system in Japan is an important issue. This study aimed to explore the risk factors related to the deterioration of health among service users at the support level of LTCI.
Methods
The participants were 200 Japanese community-dwelling older adults aged ≥ 65 years who were newly certificated as “support level” and used preventive care services. The users’ physical and cognitive conditions were assessed based on the primary doctor’s opinion and the Kihon checklist. The outcome event was defined as certification at care level 1 or higher. Cox models were used to assess the risk of health deterioration, with adjustments for age, sex, family composition, body mass index, frailty, stroke, dementia status, baseline support level, and social participation in community support projects in the LTCI system.
Results
The 5-year support level maintenance rate was 49.1 %. Male gender (hazard ratio [HR] = 1.7), support level 2 (HR = 2.1), and dementia (HR = 2.1) were identified as factors associated with an adverse outcome, whereas social participation was identified as a preventive outcome (HR = 0.4).
Conclusions
Male gender, support level 2, and dementia were associated with health deterioration among users from the support level to the care level in the LTCI system in Japan. On the other hand, social participation in community support projects may delay deterioration of health.
{"title":"Risk factors for older people utilizing care services in the long-term care insurance system","authors":"Takahiro Nishida , Ayumi Honda , Kenichiro Fukuda , Yoshihiko Ide , Sumihisa Honda","doi":"10.1016/j.aggp.2025.100235","DOIUrl":"10.1016/j.aggp.2025.100235","url":null,"abstract":"<div><h3>Background</h3><div>Preventing the deterioration of health of older adults who need preventive care services from the “support level” to the “care level” in the long-term care insurance (LTCI) system in Japan is an important issue. This study aimed to explore the risk factors related to the deterioration of health among service users at the support level of LTCI.</div></div><div><h3>Methods</h3><div>The participants were 200 Japanese community-dwelling older adults aged ≥ 65 years who were newly certificated as “support level” and used preventive care services. The users’ physical and cognitive conditions were assessed based on the primary doctor’s opinion and the Kihon checklist. The outcome event was defined as certification at care level 1 or higher. Cox models were used to assess the risk of health deterioration, with adjustments for age, sex, family composition, body mass index, frailty, stroke, dementia status, baseline support level, and social participation in community support projects in the LTCI system.</div></div><div><h3>Results</h3><div>The 5-year support level maintenance rate was 49.1 %. Male gender (hazard ratio [HR] = 1.7), support level 2 (HR = 2.1), and dementia (HR = 2.1) were identified as factors associated with an adverse outcome, whereas social participation was identified as a preventive outcome (HR = 0.4).</div></div><div><h3>Conclusions</h3><div>Male gender, support level 2, and dementia were associated with health deterioration among users from the support level to the care level in the LTCI system in Japan. On the other hand, social participation in community support projects may delay deterioration of health.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100235"},"PeriodicalIF":0.0,"publicationDate":"2025-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145685278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to investigate the association between serum high-sensitivity C-reactive protein (hs-CRP) levels, cognitive function, and brain structure in community-dwelling older adults aged 65 years and older. Given the role of inflammation in neurodegeneration, we hypothesized that higher hs-CRP levels would be associated with hippocampal volume and cognitive performance.
Methods
This cross-sectional study included 93 participants (25 men, 68 women) from Kurokawa-cho, Japan. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), and Clinical Dementia Rating (CDR). Serum hs-CRP levels were measured using an enzyme-linked immunosorbent assay. Brain structural analysis was conducted using voxel-based morphometry (VBM) on MRI scans. Multiple regression analyses were performed, adjusting for age, sex, years of education, and total intracranial volume.
Results
Serum hs-CRP levels were not significantly associated with cognitive function scores. However, VBM analysis revealed a significant negative association between hs-CRP levels and brain volume in the region including the right hippocampus (P < 0.05, corrected for multiple comparisons using family-wise error and false discovery rate corrections). A similar negative association was observed in the region including the left hippocampus, though it did not reach statistical significance.
Conclusions
These findings suggest that systemic inflammation, as indicated by hs-CRP levels, may be linked to smaller hippocampal volume in older adults, independent of cognitive function. This potential association highlights the role of inflammation in brain aging and underscores the importance of preventive healthcare strategies aimed at mitigating inflammation-related neurodegeneration.
{"title":"Brain health and inflammation in older adults: Preventive care insights from the association between high-sensitivity CRP and hippocampal volume","authors":"Ryuzo Orihashi , Narumi Fujino , Yoshito Mizoguchi","doi":"10.1016/j.aggp.2025.100233","DOIUrl":"10.1016/j.aggp.2025.100233","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to investigate the association between serum high-sensitivity C-reactive protein (hs-CRP) levels, cognitive function, and brain structure in community-dwelling older adults aged 65 years and older. Given the role of inflammation in neurodegeneration, we hypothesized that higher hs-CRP levels would be associated with hippocampal volume and cognitive performance.</div></div><div><h3>Methods</h3><div>This cross-sectional study included 93 participants (25 men, 68 women) from Kurokawa-cho, Japan. Cognitive function was assessed using the Mini-Mental State Examination (MMSE), Frontal Assessment Battery (FAB), and Clinical Dementia Rating (CDR). Serum hs-CRP levels were measured using an enzyme-linked immunosorbent assay. Brain structural analysis was conducted using voxel-based morphometry (VBM) on MRI scans. Multiple regression analyses were performed, adjusting for age, sex, years of education, and total intracranial volume.</div></div><div><h3>Results</h3><div>Serum hs-CRP levels were not significantly associated with cognitive function scores. However, VBM analysis revealed a significant negative association between hs-CRP levels and brain volume in the region including the right hippocampus (<em>P</em> < 0.05, corrected for multiple comparisons using family-wise error and false discovery rate corrections). A similar negative association was observed in the region including the left hippocampus, though it did not reach statistical significance.</div></div><div><h3>Conclusions</h3><div>These findings suggest that systemic inflammation, as indicated by hs-CRP levels, may be linked to smaller hippocampal volume in older adults, independent of cognitive function. This potential association highlights the role of inflammation in brain aging and underscores the importance of preventive healthcare strategies aimed at mitigating inflammation-related neurodegeneration.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100233"},"PeriodicalIF":0.0,"publicationDate":"2025-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145685384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In super-aged societies, preventing frailty is a key public health priority to ensure longer, healthier lives. Locomotive syndrome (LS), defined as impaired mobility because of musculoskeletal dysfunction, is a modifiable risk factor for frailty. However, the association between LS severity and pre-frailty has not yet been fully elucidated. This study sought to clarify whether the degree of LS is related to pre-frailty among community-dwelling older adults.
Methods
This cross-sectional analysis included data from the DETECt-L cohort (2021–2024). The severity of LS was evaluated in adults aged 65 years and older using three measures: the two-step test, the stand-up test, and the 25-item Geriatric Locomotive Function Scale. Pre-frailty was assessed using the Japanese adaptation of the Cardiovascular Health Study criteria. The association between LS severity and pre-frailty was analyzed using binary logistic regression, with adjustments for age, sex, body mass index, back and knee pain, and history of falls.
Results
Among 512 participants, the prevalence of pre-frailty increased with LS severity. Compared with participants in the non-LS, the proportion of pre-frailty was higher in LS stage 2 (OR: 2.184, 95% CI: 1.094–4.358, P = 0.027), and the same was true for LS stage 3 (OR: 2.254, 95% CI: 1.032–4.922, P = 0.041).
Conclusions
In independently living older adults, LS stage 2 or higher was significantly associated with pre-frailty. Preventing the transition from stage 1 to stage 2 may help reduce pre-frailty risk and support healthy aging. Early orthopedic management of LS could serve as a strategic approach to mitigate frailty in super-aged societies.
在超老龄化社会，预防虚弱是确保更长寿、更健康生活的一项关键公共卫生优先事项。机车综合征（LS），被定义为由于肌肉骨骼功能障碍而导致的活动能力受损，是一种可改变的脆弱危险因素。然而，LS严重程度与前期虚弱之间的关系尚未完全阐明。本研究旨在澄清在社区居住的老年人中，LS的程度是否与前期虚弱有关。方法本横断面分析包括来自DETECt-L队列（2021-2024）的数据。采用两步测试、站立测试和25项老年机车功能量表对65岁及以上成人的LS严重程度进行评估。采用日本心血管健康研究标准对虚弱前期进行评估。使用二元logistic回归分析LS严重程度与前期虚弱之间的关系，并调整年龄、性别、体重指数、背部和膝盖疼痛以及跌倒史。结果在512名参与者中，随着LS严重程度的增加，虚弱前期的患病率增加。与非LS的参与者相比，LS第2期的预衰弱比例更高（OR: 2.184, 95% CI: 1.094-4.358, P = 0.027）， LS第3期也是如此（OR: 2.254, 95% CI: 1.032-4.922, P = 0.041）。结论在独立生活的老年人中，LS 2期及以上与虚弱前期显著相关。防止从第一阶段过渡到第二阶段可能有助于减少脆弱前风险，并支持健康老龄化。LS的早期矫形管理可以作为一种战略方法来减轻超高龄社会的脆弱性。
{"title":"Association between locomotive syndrome and pre-frailty in community-dwelling older adults: A cross-sectional study","authors":"Junji Nishimoto , Kazuaki Hamada , Naoki Deguchi , Ryo Tanaka","doi":"10.1016/j.aggp.2025.100230","DOIUrl":"10.1016/j.aggp.2025.100230","url":null,"abstract":"<div><h3>Background</h3><div>In super-aged societies, preventing frailty is a key public health priority to ensure longer, healthier lives. Locomotive syndrome (LS), defined as impaired mobility because of musculoskeletal dysfunction, is a modifiable risk factor for frailty. However, the association between LS severity and pre-frailty has not yet been fully elucidated. This study sought to clarify whether the degree of LS is related to pre-frailty among community-dwelling older adults.</div></div><div><h3>Methods</h3><div>This cross-sectional analysis included data from the DETECt-L cohort (2021–2024). The severity of LS was evaluated in adults aged 65 years and older using three measures: the two-step test, the stand-up test, and the 25-item Geriatric Locomotive Function Scale. Pre-frailty was assessed using the Japanese adaptation of the Cardiovascular Health Study criteria. The association between LS severity and pre-frailty was analyzed using binary logistic regression, with adjustments for age, sex, body mass index, back and knee pain, and history of falls.</div></div><div><h3>Results</h3><div>Among 512 participants, the prevalence of pre-frailty increased with LS severity. Compared with participants in the non-LS, the proportion of pre-frailty was higher in LS stage 2 (OR: 2.184, 95% CI: 1.094–4.358, <em>P</em> = 0.027), and the same was true for LS stage 3 (OR: 2.254, 95% CI: 1.032–4.922, <em>P</em> = 0.041).</div></div><div><h3>Conclusions</h3><div>In independently living older adults, LS stage 2 or higher was significantly associated with pre-frailty. Preventing the transition from stage 1 to stage 2 may help reduce pre-frailty risk and support healthy aging. Early orthopedic management of LS could serve as a strategic approach to mitigate frailty in super-aged societies.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100230"},"PeriodicalIF":0.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-11-17DOI: 10.1016/j.aggp.2025.100232
Neelu Jain Gupta , Priyanka Grover , Nisha Singh
The present study depicts differences in sleep behavior, activity, and light exposure of homemakers and office-going women of urban India using a questionnaire survey, actigraphy, and urinary melatonin assay. Self-reported surveys filled by 1316 office-going and 1393 homemaker women (ages 18–79 years) comprised 7 brief questions, viz. body mass index (BMI), work-hours, sleep characteristics etc. We predicted that differences in sleep timings and daily activity patterns of urban Indian women were related to occupational routines, specifically among office-going and homemaker women. Results suggested associativity and relative risk for altered sleep length and recreation with age and occupation. Sleep onset in young and old office-going women was delayed, not in the middle-aged. Objective measurement of sleep, daily activity, and light exposure suggested disrupted Sunday activity than weekdays. Externally managed work-rest cycles in office-goers during weekdays consolidated daily activity patterns. During weekdays, homemakers exhibited greater intraday activity variability. Photometric luminance data using actigraphy revealed homemakers experienced greater exposure to brighter morning light intensities compared to office-going women, although urinary melatonin levels did not differ among groups. The variation in associativity of light-activity during weekdays depicted better light-activity coupling in homemakers. Our observation of delayed sleep onset, in office-goers needs attention because it is an established risk factor to various lifestyle disorders.. Using multimodal methodology of subjective and objective measures, our study validates age-related sleep onset timing, a hidden factor in contemporary health issues.
{"title":"Sleep timing worsening with age? Visit outdoor-light daily: A cross-sectional study of homemakers and office-going women","authors":"Neelu Jain Gupta , Priyanka Grover , Nisha Singh","doi":"10.1016/j.aggp.2025.100232","DOIUrl":"10.1016/j.aggp.2025.100232","url":null,"abstract":"<div><div>The present study depicts differences in sleep behavior, activity, and light exposure of homemakers and office-going women of urban India using a questionnaire survey, actigraphy, and urinary melatonin assay. Self-reported surveys filled by 1316 office-going and 1393 homemaker women (ages 18–79 years) comprised 7 brief questions, viz. body mass index (BMI), work-hours, sleep characteristics etc. We predicted that differences in sleep timings and daily activity patterns of urban Indian women were related to occupational routines, specifically among office-going and homemaker women. Results suggested associativity and relative risk for altered sleep length and recreation with age and occupation. Sleep onset in young and old office-going women was delayed, not in the middle-aged. Objective measurement of sleep, daily activity, and light exposure suggested disrupted Sunday activity than weekdays. Externally managed work-rest cycles in office-goers during weekdays consolidated daily activity patterns. During weekdays, homemakers exhibited greater intraday activity variability. Photometric luminance data using actigraphy revealed homemakers experienced greater exposure to brighter morning light intensities compared to office-going women, although urinary melatonin levels did not differ among groups. The variation in associativity of light-activity during weekdays depicted better light-activity coupling in homemakers. Our observation of delayed sleep onset, in office-goers needs attention because it is an established risk factor to various lifestyle disorders.. Using multimodal methodology of subjective and objective measures, our study validates age-related sleep onset timing, a hidden factor in contemporary health issues.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"3 1","pages":"Article 100232"},"PeriodicalIF":0.0,"publicationDate":"2025-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145618484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aims to determine whether frailty, assessed using the simple multidimensional frailty assessment tool, the Kihon Checklist (KCL), is associated with future fractures and, if so, to identify which frailty subtypes exhibit the strongest association with fracture incidence.
Methods
This study recruited local residents who visited government-organized examination sites for specific health check-ups for older adults, conducted over a three-day period each year and 468 community-dwelling older adults from 2014 to 2023 in Hino Town, Tottori Prefecture, Japan. Characteristics, physical structure and performance, and frailty were assessed at the baseline assessment. Frailty was assessed using KCL and categorized into six subtypes: lower motor function, malnutritional, lower oral function, housebound, reduced cognitive function, and possible depression. Self-Reported incidence fracture was determined through annual follow-up surveys. Kaplan-Meier survival analysis and Cox proportional hazards models were used to evaluate the association between frailty subtypes and fracture incidence.
Results
A total of 352 participants were followed for fracture incidence over a mean period of 6.9 years. During the follow-up period, 41 participants experienced at least one fracture, resulting in an incidence rate of 1.69 per 100 person-years. Both lower motor function and housebound were significantly associated with fracture incidence. However, after adjusting for previous fall history, and lower bone mass, housebound (HR = 2.436, 95 % CI: 1.125–5.271) remained significantly associated with fracture incidence.
Conclusions
Unlike previous studies emphasizing musculoskeletal frailty, our findings highlight housebound status as a factor associated with fractures. Fracture prevention strategies should integrate social engagement interventions alongside conventional musculoskeletal management.
{"title":"Social frailty reflected by housebound status as an independent predictor of self-reported incidence fracture in community-dwelling older adults: A longitudinal cohort study","authors":"Hiromi Matsumoto , Chika Tanimura , Yuki Kitsuda , Takashi Wada , Shinji Tanishima , Hiroshi Hagino","doi":"10.1016/j.aggp.2025.100229","DOIUrl":"10.1016/j.aggp.2025.100229","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aims to determine whether frailty, assessed using the simple multidimensional frailty assessment tool, the Kihon Checklist (KCL), is associated with future fractures and, if so, to identify which frailty subtypes exhibit the strongest association with fracture incidence.</div></div><div><h3>Methods</h3><div>This study recruited local residents who visited government-organized examination sites for specific health check-ups for older adults, conducted over a three-day period each year and 468 community-dwelling older adults from 2014 to 2023 in Hino Town, Tottori Prefecture, Japan. Characteristics, physical structure and performance, and frailty were assessed at the baseline assessment. Frailty was assessed using KCL and categorized into six subtypes: lower motor function, malnutritional, lower oral function, housebound, reduced cognitive function, and possible depression. Self-Reported incidence fracture was determined through annual follow-up surveys. Kaplan-Meier survival analysis and Cox proportional hazards models were used to evaluate the association between frailty subtypes and fracture incidence.</div></div><div><h3>Results</h3><div>A total of 352 participants were followed for fracture incidence over a mean period of 6.9 years. During the follow-up period, 41 participants experienced at least one fracture, resulting in an incidence rate of 1.69 per 100 person-years. Both lower motor function and housebound were significantly associated with fracture incidence. However, after adjusting for previous fall history, and lower bone mass, <em>housebound</em> (HR = 2.436, 95 % CI: 1.125–5.271) remained significantly associated with fracture incidence.</div></div><div><h3>Conclusions</h3><div>Unlike previous studies emphasizing musculoskeletal frailty, our findings highlight housebound status as a factor associated with fractures. Fracture prevention strategies should integrate social engagement interventions alongside conventional musculoskeletal management.</div></div>","PeriodicalId":100119,"journal":{"name":"Archives of Gerontology and Geriatrics Plus","volume":"2 4","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2025-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145571450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号