Pub Date : 2024-11-17DOI: 10.1016/j.nwnano.2024.100061
Xiaolan Luo, Weixiong Li, Liu Yuan, Guangzhong Xie, Yuanjie Su
Pyroelectricity enables autonomous perception and remote detection in the field of infrared sensor, human machine interfacing and virtual reality. However, the low pyroelectric coefficient and inferior thermal conductivity hinders the energy conversion and signal transduction of pyroelectric sensors. Herein, we designed and prepared PZT-CNT/PVDF ternary composite (PTC) capable of infrared sensing and noncontact human machine interfacing (HMI). The incorporation of CNT not only facilitates the photo-thermal energy conversion and the heat transfer toward embedded PZT fillers, but also boost the all-trans conformation of fluoropolymer matrix and thus pyroelectric activity. The influence of CNT doping mass fractions on the pyroelectric noncontacted HMI and infrared detection properties was investigated. It is found that a doping content of 3 wt% gives rise to an optimal proximity sensitivity of 55.78 % and infrared detection optimum value of Fd 6.42 μPa−1/2, which is 13.97 % higher than that of the undoped version. This work provides insight into the interfacial coupling mechanism of pyroelectrics, and offers the new possibility for design of high-performance self-powered sensing devices.
{"title":"Self-powered infrared detector enabled by interfacial anchoring and thermal reinforcement","authors":"Xiaolan Luo, Weixiong Li, Liu Yuan, Guangzhong Xie, Yuanjie Su","doi":"10.1016/j.nwnano.2024.100061","DOIUrl":"10.1016/j.nwnano.2024.100061","url":null,"abstract":"<div><div>Pyroelectricity enables autonomous perception and remote detection in the field of infrared sensor, human machine interfacing and virtual reality. However, the low pyroelectric coefficient and inferior thermal conductivity hinders the energy conversion and signal transduction of pyroelectric sensors. Herein, we designed and prepared PZT-CNT/PVDF ternary composite (PTC) capable of infrared sensing and noncontact human machine interfacing (HMI). The incorporation of CNT not only facilitates the photo-thermal energy conversion and the heat transfer toward embedded PZT fillers, but also boost the <em>all-trans</em> conformation of fluoropolymer matrix and thus pyroelectric activity. The influence of CNT doping mass fractions on the pyroelectric noncontacted HMI and infrared detection properties was investigated. It is found that a doping content of 3 wt% gives rise to an optimal proximity sensitivity of 55.78 % and infrared detection optimum value of F<sub>d</sub> 6.42 μPa<sup>−1/2</sup>, which is 13.97 % higher than that of the undoped version. This work provides insight into the interfacial coupling mechanism of pyroelectrics, and offers the new possibility for design of high-performance self-powered sensing devices.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100061"},"PeriodicalIF":0.0,"publicationDate":"2024-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-16DOI: 10.1016/j.nwnano.2024.100060
Tanvir Ahmed
Advancements in cancer immunotherapy have been notable; however, challenges remain regarding precision and the capacity to generate robust immune responses. This review explores the potential of DNA origami, an innovative method for structuring DNA into complex forms, as a platform for advanced cancer vaccines. DNA origami enables precise control over the molecular arrangement on its surface. Researchers can precisely modulate the immune response by conjugating tumor-specific antigens and adjuvants to DNA origami nanocarriers. This targeted approach demonstrates significant promise in overcoming the shortcomings of existing immunotherapies. This may enhance vaccine efficacy by facilitating the efficient delivery of antigens and adjuvants to immune cells. The precise control of adjuvant placement can minimize unnecessary immune stimulation and reduce unwanted side effects. The modular structure of DNA origami facilitates the development of personalized vaccines aimed at targeting specific mutations present in a patient's tumor. This advancement offers significant potential for bringing in a new era of precise cancer therapy. DNA origami nanocarriers demonstrate significant potential in enhancing the safety, efficacy, and precision of cancer immunotherapies.
癌症免疫疗法取得了显著进展,但在精确性和产生强大免疫反应的能力方面仍存在挑战。本综述探讨了 DNA 折纸作为先进癌症疫苗平台的潜力,DNA 折纸是一种将 DNA 结构化为复杂形式的创新方法。DNA 折纸能精确控制其表面的分子排列。研究人员可以通过将肿瘤特异性抗原和佐剂与 DNA 折纸纳米载体结合来精确调节免疫反应。这种有针对性的方法在克服现有免疫疗法的缺陷方面大有可为。这可以促进抗原和佐剂有效地传递到免疫细胞,从而提高疫苗的疗效。精确控制佐剂的放置可最大限度地减少不必要的免疫刺激,降低不必要的副作用。DNA 折纸的模块化结构有助于开发针对患者肿瘤中特定突变的个性化疫苗。这一进步为开创癌症精准治疗的新时代提供了巨大潜力。DNA 折纸纳米载体在提高癌症免疫疗法的安全性、有效性和精确性方面具有巨大潜力。
{"title":"DNA origami-based nano-vaccines for cancer immunotherapy","authors":"Tanvir Ahmed","doi":"10.1016/j.nwnano.2024.100060","DOIUrl":"10.1016/j.nwnano.2024.100060","url":null,"abstract":"<div><div>Advancements in cancer immunotherapy have been notable; however, challenges remain regarding precision and the capacity to generate robust immune responses. This review explores the potential of DNA origami, an innovative method for structuring DNA into complex forms, as a platform for advanced cancer vaccines. DNA origami enables precise control over the molecular arrangement on its surface. Researchers can precisely modulate the immune response by conjugating tumor-specific antigens and adjuvants to DNA origami nanocarriers. This targeted approach demonstrates significant promise in overcoming the shortcomings of existing immunotherapies. This may enhance vaccine efficacy by facilitating the efficient delivery of antigens and adjuvants to immune cells. The precise control of adjuvant placement can minimize unnecessary immune stimulation and reduce unwanted side effects. The modular structure of DNA origami facilitates the development of personalized vaccines aimed at targeting specific mutations present in a patient's tumor. This advancement offers significant potential for bringing in a new era of precise cancer therapy. DNA origami nanocarriers demonstrate significant potential in enhancing the safety, efficacy, and precision of cancer immunotherapies.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100060"},"PeriodicalIF":0.0,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-10DOI: 10.1016/j.nwnano.2024.100059
Rodrigo L.M.S. Oliveira , Lucas Barbosa , Thaís C. Pereira , Luísa R.M. Dona , Thiago G. Tabuti , Dayane B. Tada , Eduardo R. Triboni , Luciane D. de Oliveira , Eliandra S. Trichês
Incorporating nanoparticles into scaffolds with regenerative potential is a promissory strategy to provide them with antimicrobial activity. Bioceramics, such as β-tricalcium phosphate (β-TCP) and bioactive glasses (BGs), stand out among synthetic materials for bone regeneration. In this context, we report the incorporation of zinc oxide (ZnO) and copper oxide/copper nitrate (CuO/Cu2H3NO5) nanoparticles onto the surface of the β-TCP/BG scaffolds. This report addresses the physicochemical characterization of the scaffolds, their antimicrobial activity, and their response to MC3T3-E1 cells. Our findings show that the incorporation of both nanoparticles effectively inhibited S. aureus growth, including its biofilm formation. While the presence of the nanoparticles initially decreased MC3T3-E1 cell viability, cell proliferation improved with prolonged incubation. Overall, the β-TCP/BG_Zn and β-TCP/BG_Cu scaffolds showed an early antimicrobial response, aiding infection eradication, while also supporting cell proliferation over time.
{"title":"Multifunctional scaffolds of β-tricalcium phosphate/bioactive glass coated with zinc oxide and copper oxide nanoparticles","authors":"Rodrigo L.M.S. Oliveira , Lucas Barbosa , Thaís C. Pereira , Luísa R.M. Dona , Thiago G. Tabuti , Dayane B. Tada , Eduardo R. Triboni , Luciane D. de Oliveira , Eliandra S. Trichês","doi":"10.1016/j.nwnano.2024.100059","DOIUrl":"10.1016/j.nwnano.2024.100059","url":null,"abstract":"<div><div>Incorporating nanoparticles into scaffolds with regenerative potential is a promissory strategy to provide them with antimicrobial activity. Bioceramics, such as β-tricalcium phosphate (β-TCP) and bioactive glasses (BGs), stand out among synthetic materials for bone regeneration. In this context, we report the incorporation of zinc oxide (ZnO) and copper oxide/copper nitrate (CuO/Cu<sub>2</sub>H<sub>3</sub>NO<sub>5</sub>) nanoparticles onto the surface of the β-TCP/BG scaffolds. This report addresses the physicochemical characterization of the scaffolds, their antimicrobial activity, and their response to MC3T3-E1 cells. Our findings show that the incorporation of both nanoparticles effectively inhibited <em>S. aureus</em> growth<em>,</em> including its biofilm formation. While the presence of the nanoparticles initially decreased MC3T3-E1 cell viability, cell proliferation improved with prolonged incubation. Overall, the β-TCP/BG_Zn and β-TCP/BG_Cu scaffolds showed an early antimicrobial response, aiding infection eradication, while also supporting cell proliferation over time.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100059"},"PeriodicalIF":0.0,"publicationDate":"2024-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-08DOI: 10.1016/j.nwnano.2024.100058
Patricio G. Márquez , Federico J. Wolman , Romina J. Glisoni
Vaccines represent a cornerstone in global health history, marking one of the most significant scientific achievements. Initially consisting of live or attenuated microorganisms, vaccines have evolved to include subunit vaccines, which offer greater specificity, safety, and production advantages. However, subunit vaccines require adjuvants due to the low immunogenicity of their antigens. These adjuvants include immunostimulatory molecules and particulate systems, which serve as carriers for both antigens and immunostimulants. The nanoscale dimensions of these particulate systems confer distinct advantages. This review comprehensively discusses FDA- and EMA-approved vaccines that incorporate adjuvants, emphasizing the growing use of nanoparticulate adjuvants in enhancing vaccine efficacy and safety. The unique physicochemical properties of nanoscopic systems, such as hydrodynamic size, shape, surface charge, hydrophobicity and degradation profiles are explored, that determine their effectiveness in vaccine formulations.
Furthermore, innovations in production scalability and alternative delivery routes, such as oral or transdermal vaccines, offer promising solutions to global vaccine accessibility challenges, particularly in resource-limited settings. The ongoing integration of nanotechnology platforms thus continues to expand the potential of vaccines, ensuring safer, more effective, and more accessible solutions for global immunization efforts.
疫苗是全球卫生史上的基石,标志着最重要的科学成就之一。疫苗最初由活的或减毒的微生物组成,现在已发展到包括亚单位疫苗在内的疫苗,亚单位疫苗具有更高的特异性、安全性和生产优势。然而,由于亚单位疫苗抗原的免疫原性较低,因此需要使用佐剂。这些佐剂包括免疫刺激分子和微粒系统,可作为抗原和免疫刺激剂的载体。这些微粒系统的纳米级尺寸具有独特的优势。本综述全面讨论了 FDA 和 EMA 批准的含有佐剂的疫苗,强调了纳米颗粒佐剂在提高疫苗功效和安全性方面日益广泛的应用。此外,生产可扩展性和替代给药途径(如口服或透皮疫苗)方面的创新为全球疫苗可及性挑战提供了前景广阔的解决方案,尤其是在资源有限的环境中。因此,纳米技术平台的不断整合将继续扩大疫苗的潜力,确保为全球免疫工作提供更安全、更有效、更易获得的解决方案。
{"title":"Nanotechnology platforms for antigen and immunostimulant delivery in vaccine formulations","authors":"Patricio G. Márquez , Federico J. Wolman , Romina J. Glisoni","doi":"10.1016/j.nwnano.2024.100058","DOIUrl":"10.1016/j.nwnano.2024.100058","url":null,"abstract":"<div><div>Vaccines represent a cornerstone in global health history, marking one of the most significant scientific achievements. Initially consisting of live or attenuated microorganisms, vaccines have evolved to include subunit vaccines, which offer greater specificity, safety, and production advantages. However, subunit vaccines require adjuvants due to the low immunogenicity of their antigens. These adjuvants include immunostimulatory molecules and particulate systems, which serve as carriers for both antigens and immunostimulants. The nanoscale dimensions of these particulate systems confer distinct advantages. This review comprehensively discusses FDA- and EMA-approved vaccines that incorporate adjuvants, emphasizing the growing use of nanoparticulate adjuvants in enhancing vaccine efficacy and safety. The unique physicochemical properties of nanoscopic systems, such as hydrodynamic size, shape, surface charge, hydrophobicity and degradation profiles are explored, that determine their effectiveness in vaccine formulations.</div><div>Furthermore, innovations in production scalability and alternative delivery routes, such as oral or transdermal vaccines, offer promising solutions to global vaccine accessibility challenges, particularly in resource-limited settings. The ongoing integration of nanotechnology platforms thus continues to expand the potential of vaccines, ensuring safer, more effective, and more accessible solutions for global immunization efforts.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100058"},"PeriodicalIF":0.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142703699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-03DOI: 10.1016/j.nwnano.2024.100057
Xindan Hui , Hengyu Guo
Cardiac sounds sensor as a noninvasive instrument plays a pivotal role in the early diagnosis of various heart disease. In recent years, triboelectric nanogenerators (TENGs) have been employed widely for sensing different physiological information benefiting from abundant materials choices, simplicity of construction and low cost. More importantly, the fast saturated constitutive characteristic of the contact-separation mode (C-S) TENG demonstrates ultrahigh sensitivity in the detection of micromechanical quantities than traditional piezoelectric sensing mechanism. This article presents an overview of the C-S TENG enabled self-powered cardiac sounds monitoring, focusing on the working principle, performance comparison between C-S TENG and piezoelectric generator (PEG), and related applications. The challenges and future research directions of cardiac sounds sensor and C-S TENG toward micro-displacement region have also been proposed.
心音传感器作为一种无创仪器,在各种心脏病的早期诊断中发挥着举足轻重的作用。近年来,三电纳米发生器(TENGs)以其材料选择丰富、构造简单、成本低廉等优点被广泛应用于传感不同的生理信息。更重要的是,与传统的压电传感机制相比,接触分离模式(C-S)三电纳米发生器的快速饱和构成特性在检测微机械量方面具有超高灵敏度。本文概述了 C-S TENG 的工作原理、C-S TENG 与压电发生器 (PEG) 的性能比较以及相关应用,并介绍了实现自供电心音监测的 C-S TENG。此外,还提出了心音传感器和 C-S TENG 面向微位移区域的挑战和未来研究方向。
{"title":"Advances in cardiac sounds monitoring enabled by triboelectric sensors","authors":"Xindan Hui , Hengyu Guo","doi":"10.1016/j.nwnano.2024.100057","DOIUrl":"10.1016/j.nwnano.2024.100057","url":null,"abstract":"<div><div>Cardiac sounds sensor as a noninvasive instrument plays a pivotal role in the early diagnosis of various heart disease. In recent years, triboelectric nanogenerators (TENGs) have been employed widely for sensing different physiological information benefiting from abundant materials choices, simplicity of construction and low cost. More importantly, the fast saturated constitutive characteristic of the contact-separation mode (C-S) TENG demonstrates ultrahigh sensitivity in the detection of micromechanical quantities than traditional piezoelectric sensing mechanism. This article presents an overview of the C-S TENG enabled self-powered cardiac sounds monitoring, focusing on the working principle, performance comparison between C-S TENG and piezoelectric generator (PEG), and related applications. The challenges and future research directions of cardiac sounds sensor and C-S TENG toward micro-displacement region have also been proposed.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100057"},"PeriodicalIF":0.0,"publicationDate":"2024-11-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142661329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-15DOI: 10.1016/j.nwnano.2024.100056
Aditya Saran , Shuai Hou , Yinglu Ji
The amplification of signals is dependent upon enzyme/ catalyst. Enzyme activity, specificity, pH condition, enzyme linkers, stability, storage and efficiency are some very important factors that can eventually affect the detection results. We aimed to amplify signals without the assistance of enzyme/ catalyst so that the strategy can be used in the wide range of signal detection including immune-assay. Silver nanocrystals (Ag NCs) grown from self-nucleation are used as chromogens due to their strong plasmon band at ∼ 400 nm. During 140 s of reaction time in presence of 6.10 mM CTAB and 0.61 mM of AgNO3, the 0.57 mM of Ascorbic acid allows Ag over growth on antibody-tagged gold nanospheres (10±0.5 nm) that competes silver atoms from the self-nucleation growth and thus affects the growth kinetics of the latter. By utilizing the opened kinetic window, sensitive detection has been achieved from 6.67 × 10–14 M (1 pg) to 3.33 × 10–9 M (50 ng) using human IgG as a model protein. The non-catalytic plasmonic immunoabsorbant assay we developed herein adds a new possibility of plasmonic NPs for sensitive detection. The detection slope and resolution is higher and better than those via signal amplification through the assistance of enzymes/ catalysts. This work supports the concept that nanoparticles mediated reactions are sensitive enough that they have the potential to go independently without enzymes/ catalyst assistance.
{"title":"A novel non-catalytic plasmonic immunoabsorbant assay amplification mechanism","authors":"Aditya Saran , Shuai Hou , Yinglu Ji","doi":"10.1016/j.nwnano.2024.100056","DOIUrl":"10.1016/j.nwnano.2024.100056","url":null,"abstract":"<div><div>The amplification of signals is dependent upon enzyme/ catalyst. Enzyme activity, specificity, pH condition, enzyme linkers, stability, storage and efficiency are some very important factors that can eventually affect the detection results. We aimed to amplify signals without the assistance of enzyme/ catalyst so that the strategy can be used in the wide range of signal detection including immune-assay. Silver nanocrystals (Ag NCs) grown from self-nucleation are used as chromogens due to their strong plasmon band at ∼ 400 nm. During 140 s of reaction time in presence of 6.10 mM CTAB and 0.61 mM of AgNO<sub>3</sub>, the 0.57 mM of Ascorbic acid allows Ag over growth on antibody-tagged gold nanospheres (10±0.5 nm) that competes silver atoms from the self-nucleation growth and thus affects the growth kinetics of the latter. By utilizing the opened kinetic window, sensitive detection has been achieved from 6.67 × 10<sup>–14</sup> M (1 pg) to 3.33 × 10<sup>–9</sup> M (50 ng) using human IgG as a model protein. The non-catalytic plasmonic immunoabsorbant assay we developed herein adds a new possibility of plasmonic NPs for sensitive detection. The detection slope and resolution is higher and better than those via signal amplification through the assistance of enzymes/ catalysts. This work supports the concept that nanoparticles mediated reactions are sensitive enough that they have the potential to go independently without enzymes/ catalyst assistance.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100056"},"PeriodicalIF":0.0,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142532506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-05DOI: 10.1016/j.nwnano.2024.100055
Da Woon Jin , Hyun Soo Ahn , Dheeraj Kumar , Joo Hyeong Lee , Min Su Kim , Yushin Eom , Ji Ho Youk , Huidrom Hemojit Singh , Jong Hun Kim , Jong Hoon Jung
To date, there have been a lot of efforts to enhance the conversion efficiency of triboelectric nanogenerators (TENGs) via physical and chemical modifications of the polymer surface. Herein, we report that a facile peeling of polymer from a substrate can enhance the triboelectric power output. The peeling of spin-coated polydimethylsiloxane (PDMS) from glass and polytetrafluoroethylene (PTFE) substrates has revealed a considerable increase in interfacial roughness and lateral friction. Surface-sensitive X-ray photoemission spectroscopy and non-contact current measurements have also revealed the transfer of counter-material and interfacial charging. The surface roughness of peeled PDMS is significant for the PTFE substrate, while the surface charge is significant for the glass substrate. The triboelectric output power density for peeled PDMS from the substrate is similar, 10.3 µW/cm2, but significantly larger than that for as-grown PDMS (2.2 µW/cm2). The peeling strength of PDMS significantly increases for glass compared to PTFE after the oxygen plasma treatment of substrates. The triboelectric charge of peeled PDMS from a plasma-treated glass substrate is almost 1.3 times larger than that from a PTFE substrate. This work implies that peeling polymer from a rough substrate with a large adhesion force would be a facile and effective way to increase the triboelectric power output, without any delicate surface treatments.
{"title":"Peeling-induced interfacial roughness and charging for enhanced triboelectric power generation","authors":"Da Woon Jin , Hyun Soo Ahn , Dheeraj Kumar , Joo Hyeong Lee , Min Su Kim , Yushin Eom , Ji Ho Youk , Huidrom Hemojit Singh , Jong Hun Kim , Jong Hoon Jung","doi":"10.1016/j.nwnano.2024.100055","DOIUrl":"10.1016/j.nwnano.2024.100055","url":null,"abstract":"<div><div>To date, there have been a lot of efforts to enhance the conversion efficiency of triboelectric nanogenerators (TENGs) via physical and chemical modifications of the polymer surface. Herein, we report that a facile peeling of polymer from a substrate can enhance the triboelectric power output. The peeling of spin-coated polydimethylsiloxane (PDMS) from glass and polytetrafluoroethylene (PTFE) substrates has revealed a considerable increase in interfacial roughness and lateral friction. Surface-sensitive X-ray photoemission spectroscopy and non-contact current measurements have also revealed the transfer of counter-material and interfacial charging. The surface roughness of peeled PDMS is significant for the PTFE substrate, while the surface charge is significant for the glass substrate. The triboelectric output power density for peeled PDMS from the substrate is similar, 10.3 µW/cm<sup>2</sup>, but significantly larger than that for as-grown PDMS (2.2 µW/cm<sup>2</sup>). The peeling strength of PDMS significantly increases for glass compared to PTFE after the oxygen plasma treatment of substrates. The triboelectric charge of peeled PDMS from a plasma-treated glass substrate is almost 1.3 times larger than that from a PTFE substrate. This work implies that peeling polymer from a rough substrate with a large adhesion force would be a facile and effective way to increase the triboelectric power output, without any delicate surface treatments.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100055"},"PeriodicalIF":0.0,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142417826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-10-02DOI: 10.1016/j.nwnano.2024.100054
Marjun C. Alvarado , Ma. Cristine Concepcion D. Ignacio , Ma. Camille G. Acabal , Anniver Ryan P. Lapuz , Kevin F. Yaptenco
Nanocellulose (NC) shows great potential across industries like food, pharmaceuticals, cosmetics, textiles, electronics, and construction. It can be sustainably extracted from agricultural residues using methods such as mechanical processes, acid hydrolysis, and bacterial biosynthesis. This review emphasizes the use of Response Surface Methodology (RSM) in optimizing NC extraction by examining variables like acid concentration, reaction time, and temperature. While RSM is effective, its assumptions of linear and quadratic relationships limit its accuracy in complex systems. Advanced techniques like artificial neural networks (ANN) offer a better alternative, capturing nonlinear relationships more effectively. However, ANN's application in NC extraction is underexplored, calling for future research to improve model precision. Expanding optimization to include response variables like thermal stability and surface charge is also essential for enhancing NC's industrial applications.
{"title":"Review on nanocellulose production from agricultural residue through response surface methodology and its applications","authors":"Marjun C. Alvarado , Ma. Cristine Concepcion D. Ignacio , Ma. Camille G. Acabal , Anniver Ryan P. Lapuz , Kevin F. Yaptenco","doi":"10.1016/j.nwnano.2024.100054","DOIUrl":"10.1016/j.nwnano.2024.100054","url":null,"abstract":"<div><div>Nanocellulose (NC) shows great potential across industries like food, pharmaceuticals, cosmetics, textiles, electronics, and construction. It can be sustainably extracted from agricultural residues using methods such as mechanical processes, acid hydrolysis, and bacterial biosynthesis. This review emphasizes the use of Response Surface Methodology (RSM) in optimizing NC extraction by examining variables like acid concentration, reaction time, and temperature. While RSM is effective, its assumptions of linear and quadratic relationships limit its accuracy in complex systems. Advanced techniques like artificial neural networks (ANN) offer a better alternative, capturing nonlinear relationships more effectively. However, ANN's application in NC extraction is underexplored, calling for future research to improve model precision. Expanding optimization to include response variables like thermal stability and surface charge is also essential for enhancing NC's industrial applications.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100054"},"PeriodicalIF":0.0,"publicationDate":"2024-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142417762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-29DOI: 10.1016/j.nwnano.2024.100052
David B. Olawade , Abimbola O. Ige , Abimbola G. Olaremu , James O. Ijiwade , Adedapo O. Adeola
The convergence of Artificial Intelligence (AI) and nanotechnology is a transformative frontier, holding vast potential for scientific and technological advancements. This review explores the integration of AI and nanotechnology, aiming to uncover current trends, challenges, and future directions across various domains. A scientometric approach was employed, gathering and analyzing existing literature and research in the fields of AI and nanotechnology. Through a systematic examination of recent studies and developments, we identified key trends, challenges, and potential pathways for future research and applications. Findings from this review highlight the significant impact of AI-driven nanotechnology in materials discovery and design, healthcare, environmental monitoring, energy conversion, and quantum computing. These areas have witnessed remarkable advancements, such as the development of novel nanomaterials, precise drug delivery systems, advanced nanosensors, and efficient energy storage solutions. However, challenges persist, including insufficient interdisciplinary collaboration, data quality, ethical concerns, and regulatory frameworks. While challenges require careful consideration and mitigation, the potential for innovation and progress in diverse domains is undeniable. This review underscores the importance of responsible AI use and ongoing research to unlock the full potential of this convergence, ultimately shaping the future of science and technology.
{"title":"The synergy of artificial intelligence and nanotechnology towards advancing innovation and sustainability - A mini-review","authors":"David B. Olawade , Abimbola O. Ige , Abimbola G. Olaremu , James O. Ijiwade , Adedapo O. Adeola","doi":"10.1016/j.nwnano.2024.100052","DOIUrl":"10.1016/j.nwnano.2024.100052","url":null,"abstract":"<div><div>The convergence of Artificial Intelligence (AI) and nanotechnology is a transformative frontier, holding vast potential for scientific and technological advancements. This review explores the integration of AI and nanotechnology, aiming to uncover current trends, challenges, and future directions across various domains. A scientometric approach was employed, gathering and analyzing existing literature and research in the fields of AI and nanotechnology. Through a systematic examination of recent studies and developments, we identified key trends, challenges, and potential pathways for future research and applications. Findings from this review highlight the significant impact of AI-driven nanotechnology in materials discovery and design, healthcare, environmental monitoring, energy conversion, and quantum computing. These areas have witnessed remarkable advancements, such as the development of novel nanomaterials, precise drug delivery systems, advanced nanosensors, and efficient energy storage solutions. However, challenges persist, including insufficient interdisciplinary collaboration, data quality, ethical concerns, and regulatory frameworks. While challenges require careful consideration and mitigation, the potential for innovation and progress in diverse domains is undeniable. This review underscores the importance of responsible AI use and ongoing research to unlock the full potential of this convergence, ultimately shaping the future of science and technology.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100052"},"PeriodicalIF":0.0,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142417761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-09-28DOI: 10.1016/j.nwnano.2024.100053
Yiqin Wang , Xianfa Cai , Yufeng Guo , Zhi Chen , Yunqi Cao , Wangdi Du , Tian Xia , Nelson Sepulveda , Wei Li
Ferroelectret nanogenerators (FENGs), recognized for their porous structures that facilitate charge retention, thereby creating giant electric dipoles and exhibiting remarkable piezoelectric properties, are utilized in the development of various flexible transducers. However, despite their flexibility, most developed ferroelectret nanogenerators lack adequate stretchability and satisfactory transverse piezoelectric properties, significantly inhibiting their widespread deployment in wearable or skin-mounted electronics. Here, we introduce a highly stretchable ferroelectret nanogenerator (HS-FENG) built from laser-induced graphene (LIG), Ecoflex and anhydrous ethanol, demonstrating exceptional flexibility and stretchability, along with longitudinal and transverse piezoelectric effects. The stretchability of HS-FENG can reach a record of 468 %, while the quasi-static piezoelectric coefficients d33 and d31 are approximately 120 pC/N and 70 pC/N, respectively. To our knowledge, this is the first demonstration of the developed FENG with remarkably high stretchability. Furthermore, leveraging the performance of the created HS-FENG, we construct a skin-mounted intelligent kinesiology tape capable of effectively monitoring motion signals from human muscles and joints, thereby offering a deeper understanding of movement for users across different levels of physical activity, from professional athletes to individuals undergoing rehabilitation. The development of intelligent kinesiology tape exemplifies the potential of HS-FENG technology in enhancing professional athletic training and personalized healthcare. It contributes to the advancement of inconspicuous skin-mounted biomechanical feedback systems and human-machine interfaces, marking progress in the field.
{"title":"Self-powered highly stretchable ferroelectret nanogenerator towards intelligent sports","authors":"Yiqin Wang , Xianfa Cai , Yufeng Guo , Zhi Chen , Yunqi Cao , Wangdi Du , Tian Xia , Nelson Sepulveda , Wei Li","doi":"10.1016/j.nwnano.2024.100053","DOIUrl":"10.1016/j.nwnano.2024.100053","url":null,"abstract":"<div><div>Ferroelectret nanogenerators (FENGs), recognized for their porous structures that facilitate charge retention, thereby creating giant electric dipoles and exhibiting remarkable piezoelectric properties, are utilized in the development of various flexible transducers. However, despite their flexibility, most developed ferroelectret nanogenerators lack adequate stretchability and satisfactory transverse piezoelectric properties, significantly inhibiting their widespread deployment in wearable or skin-mounted electronics. Here, we introduce a highly stretchable ferroelectret nanogenerator (HS-FENG) built from laser-induced graphene (LIG), Ecoflex and anhydrous ethanol, demonstrating exceptional flexibility and stretchability, along with longitudinal and transverse piezoelectric effects. The stretchability of HS-FENG can reach a record of 468 %, while the quasi-static piezoelectric coefficients <em>d</em><sub>33</sub> and <em>d</em><sub>31</sub> are approximately 120 pC/N and 70 pC/N, respectively. To our knowledge, this is the first demonstration of the developed FENG with remarkably high stretchability. Furthermore, leveraging the performance of the created HS-FENG, we construct a skin-mounted intelligent kinesiology tape capable of effectively monitoring motion signals from human muscles and joints, thereby offering a deeper understanding of movement for users across different levels of physical activity, from professional athletes to individuals undergoing rehabilitation. The development of intelligent kinesiology tape exemplifies the potential of HS-FENG technology in enhancing professional athletic training and personalized healthcare. It contributes to the advancement of inconspicuous skin-mounted biomechanical feedback systems and human-machine interfaces, marking progress in the field.</div></div>","PeriodicalId":100942,"journal":{"name":"Nano Trends","volume":"8 ","pages":"Article 100053"},"PeriodicalIF":0.0,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142444643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}